Name

SLC1A1 Gene

solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1

This gene encodes a member of the high-affinity glutamate transporters that play an essential role in transporting glutamate across plasma membranes. In brain, these transporters are crucial in terminating the postsynaptic action of the neurotransmitter glutamate, and in maintaining extracellular glutamate concentrations below neurotoxic levels. This transporter also transports aspartate, and mutations in this gene are thought to cause dicarboxylicamino aciduria, also known as glutamate-aspartate transport defect. [provided by RefSeq, Mar 2010]

slc1a1 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term slc1a1 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

SLC1A1 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for SLC1A1 from the Pathway Commons Protein-Protein Interactions dataset.