Name

SOCS6 Gene

suppressor of cytokine signaling 6

The protein encoded by this gene contains a SH2 domain and a CIS homolog domain. The protein thus belongs to the cytokine-induced STAT inhibitor (CIS), also known as suppressor of cytokine signaling (SOCS) or STAT-induced STAT inhibitor (SSI), protein family. CIS family members are known to be cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by GM-CSF and EPO in hematopoietic cells. A high expression level of this gene was found in factor-independent chronic myelogenous leukemia (CML) and erythroleukemia (HEL) cell lines. [provided by RefSeq, Jul 2008]

socs6 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term socs6 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

SOCS6 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for SOCS6 from the Pathway Commons Protein-Protein Interactions dataset.