Name

SOX4 Gene

SRY (sex determining region Y)-box 4

This intronless gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins, such as syndecan binding protein (syntenin). The protein may function in the apoptosis pathway leading to cell death as well as to tumorigenesis and may mediate downstream effects of parathyroid hormone (PTH) and PTH-related protein (PTHrP) in bone development. The solution structure has been resolved for the HMG-box of a similar mouse protein. [provided by RefSeq, Jul 2008]

sox4 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term sox4 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

SOX4 Gene Set

From MotifMap Predicted Transcription Factor Targets

target genes of the SOX4 transcription factor predicted using known transcription factor binding site motifs from the MotifMap Predicted Transcription Factor Targets dataset.

SOX4 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for SOX4 from the Pathway Commons Protein-Protein Interactions dataset.

sox40l Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term sox40l in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

SOX4_KD_GDS2193_37_human_adenoid cystic carcinoma derived cells ACC3 Gene Set

From GEO Signatures of Differentially Expressed Genes for Gene Perturbations

genes differentially expressed following the SOX4_KD_GDS2193_37_human_adenoid cystic carcinoma derived cells ACC3 gene perturbation from the GEO Signatures of Differentially Expressed Genes for Gene Perturbations dataset.

sox4_16636670_acc3_lof_human_gpl96_gds2193 Gene Set

From GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations

genes differentially expressed following the sox4_16636670_acc3_lof_human_gpl96_gds2193 transcription factor perturbation from the GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations dataset.