Name

SP1 Gene

Sp1 transcription factor

The protein encoded by this gene is a zinc finger transcription factor that binds to GC-rich motifs of many promoters. The encoded protein is involved in many cellular processes, including cell differentiation, cell growth, apoptosis, immune responses, response to DNA damage, and chromatin remodeling. Post-translational modifications such as phosphorylation, acetylation, glycosylation, and proteolytic processing significantly affect the activity of this protein, which can be an activator or a repressor. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2014]

SP140L Gene

SP140 nuclear body protein-like

SP100 Gene

SP100 nuclear antigen

This gene encodes a subnuclear organelle and major component of the PML (promyelocytic leukemia)-SP100 nuclear bodies. PML and SP100 are covalently modified by the SUMO-1 modifier, which is considered crucial to nuclear body interactions. The encoded protein binds heterochromatin proteins and is thought to play a role in tumorigenesis, immunity, and gene regulation. Alternatively spliced variants have been identified for this gene; one of which encodes a high-mobility group protein. [provided by RefSeq, Aug 2011]

SP140 Gene

SP140 nuclear body protein

SP110 Gene

SP110 nuclear body protein

The nuclear body is a multiprotein complex that may have a role in the regulation of gene transcription. This gene is a member of the SP100/SP140 family of nuclear body proteins and encodes a leukocyte-specific nuclear body component. The protein can function as an activator of gene transcription and may serve as a nuclear hormone receptor coactivator. In addition, it has been suggested that the protein may play a role in ribosome biogenesis and in the induction of myeloid cell differentiation. Alternative splicing has been observed for this gene and three transcript variants, encoding distinct isoforms, have been identified. [provided by RefSeq, Jul 2008]

SP1 Gene Set

From ENCODE Transcription Factor Targets

target genes of the SP1 transcription factor in ChIP-seq datasets from the ENCODE Transcription Factor Targets dataset.

sp1 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term sp1 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

SP1 Gene Set

From Hub Proteins Protein-Protein Interactions

interacting proteins for hub protein SP1 from the curated Hub Proteins Protein-Protein Interactions dataset.

SP1 Gene Set

From JASPAR Predicted Transcription Factor Targets

target genes of the SP1 transcription factor predicted using known transcription factor binding site motifs from the JASPAR Predicted Transcription Factor Targets dataset.

SP1 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for SP1 from the Pathway Commons Protein-Protein Interactions dataset.

SP1 Gene Set

From TRANSFAC Predicted Transcription Factor Targets

target genes of the SP1 transcription factor predicted using known transcription factor binding site motifs from the TRANSFAC Predicted Transcription Factor Targets dataset.

p53-SP1 complex Gene Set

From CORUM Protein Complexes

proteins in the p53-SP1 complex protein complex from the CORUM Protein Complexes dataset.

SP1-MCAF2 complex Gene Set

From CORUM Protein Complexes

proteins in the SP1-MCAF2 complex protein complex from the CORUM Protein Complexes dataset.

SMAD3-SMAD4-SP1 complex Gene Set

From CORUM Protein Complexes

proteins in the SMAD3-SMAD4-SP1 complex protein complex from the CORUM Protein Complexes dataset.

SP1-E2F1 complex Gene Set

From CORUM Protein Complexes

proteins in the SP1-E2F1 complex protein complex from the CORUM Protein Complexes dataset.

SP1049C Gene Set

From DrugBank Drug Targets

interacting proteins for the SP1049C drug from the curated DrugBank Drug Targets dataset.

SP1_HCT116_hg19_1 Gene Set

From ENCODE Transcription Factor Binding Site Profiles

genes with transcription factor binding evidence in the SP1_HCT116_hg19_1 transcription factor binding site profile from the ENCODE Transcription Factor Binding Site Profiles dataset.

SP1_A549_hg19_1 Gene Set

From ENCODE Transcription Factor Binding Site Profiles

genes with transcription factor binding evidence in the SP1_A549_hg19_1 transcription factor binding site profile from the ENCODE Transcription Factor Binding Site Profiles dataset.

SP1_HepG2_hg19_2 Gene Set

From ENCODE Transcription Factor Binding Site Profiles

genes with transcription factor binding evidence in the SP1_HepG2_hg19_2 transcription factor binding site profile from the ENCODE Transcription Factor Binding Site Profiles dataset.

SP1_HepG2_hg19_1 Gene Set

From ENCODE Transcription Factor Binding Site Profiles

genes with transcription factor binding evidence in the SP1_HepG2_hg19_1 transcription factor binding site profile from the ENCODE Transcription Factor Binding Site Profiles dataset.

SP1_GM12878_hg19_2 Gene Set

From ENCODE Transcription Factor Binding Site Profiles

genes with transcription factor binding evidence in the SP1_GM12878_hg19_2 transcription factor binding site profile from the ENCODE Transcription Factor Binding Site Profiles dataset.

SP1_GM12878_hg19_1 Gene Set

From ENCODE Transcription Factor Binding Site Profiles

genes with transcription factor binding evidence in the SP1_GM12878_hg19_1 transcription factor binding site profile from the ENCODE Transcription Factor Binding Site Profiles dataset.

SP1_A549_hg19_2 Gene Set

From ENCODE Transcription Factor Binding Site Profiles

genes with transcription factor binding evidence in the SP1_A549_hg19_2 transcription factor binding site profile from the ENCODE Transcription Factor Binding Site Profiles dataset.

SP1_H1-hESC_hg19_2 Gene Set

From ENCODE Transcription Factor Binding Site Profiles

genes with transcription factor binding evidence in the SP1_H1-hESC_hg19_2 transcription factor binding site profile from the ENCODE Transcription Factor Binding Site Profiles dataset.

SP1_H1-hESC_hg19_1 Gene Set

From ENCODE Transcription Factor Binding Site Profiles

genes with transcription factor binding evidence in the SP1_H1-hESC_hg19_1 transcription factor binding site profile from the ENCODE Transcription Factor Binding Site Profiles dataset.

SP1_HCT116_hg19_2 Gene Set

From ENCODE Transcription Factor Binding Site Profiles

genes with transcription factor binding evidence in the SP1_HCT116_hg19_2 transcription factor binding site profile from the ENCODE Transcription Factor Binding Site Profiles dataset.

SP1_K562_hg19_2 Gene Set

From ENCODE Transcription Factor Binding Site Profiles

genes with transcription factor binding evidence in the SP1_K562_hg19_2 transcription factor binding site profile from the ENCODE Transcription Factor Binding Site Profiles dataset.

SP1_K562_hg19_1 Gene Set

From ENCODE Transcription Factor Binding Site Profiles

genes with transcription factor binding evidence in the SP1_K562_hg19_1 transcription factor binding site profile from the ENCODE Transcription Factor Binding Site Profiles dataset.

sp1like Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term sp1like in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

sp1dependent Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term sp1dependent in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

sp1pomc Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term sp1pomc in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

sp1mediated Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term sp1mediated in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

sp1egr1 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term sp1egr1 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

sp1sp3 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term sp1sp3 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

sp1binding Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term sp1binding in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

sp1phosphorylation Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term sp1phosphorylation in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

sp1deficient Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term sp1deficient in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

sp100 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term sp100 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

sp1egr1repeat Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term sp1egr1repeat in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

sp13 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term sp13 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

sp17 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term sp17 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

sp110b Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term sp110b in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

sp1sp3mediated Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term sp1sp3mediated in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

sp134 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term sp134 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

sp1responsive Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term sp1responsive in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

sp110 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term sp110 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

sp1signalling Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term sp1signalling in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

sp1nfy Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term sp1nfy in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

sp1_22099172_dental_follicle_cell_gof_human_gpl11532_gse31628 Gene Set

From GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations

genes differentially expressed following the sp1_22099172_dental_follicle_cell_gof_human_gpl11532_gse31628 transcription factor perturbation from the GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations dataset.

Sperm surface protein Sp17 Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Sperm surface protein Sp17 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Nuclear body protein SP140 Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Nuclear body protein SP140 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

BL938 (SP1) Gene Set

From NURSA Protein Complexes

proteins in the BL938 (SP1) protein complex recovered by IP-MS from the NURSA Protein Complexes dataset.

SP140L Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for SP140L from the Pathway Commons Protein-Protein Interactions dataset.

SP140 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for SP140 from the Pathway Commons Protein-Protein Interactions dataset.

SP100 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for SP100 from the Pathway Commons Protein-Protein Interactions dataset.

SP110 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for SP110 from the Pathway Commons Protein-Protein Interactions dataset.