Snf2-related CREBBP activator protein

This gene encodes the core catalytic component of the multiprotein chromatin-remodeling SRCAP complex. The encoded protein is an ATPase that is necessary for the incorporation of the histone variant H2A.Z into nucleosomes. It can function as a transcriptional activator in Notch-mediated, CREB-mediated and steroid receptor-mediated transcription. Mutations in this gene cause Floating-Harbor syndrome, a rare disorder characterized by short stature, language deficits and dysmorphic facial features. [provided by RefSeq, Feb 2012]

srcap Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term srcap in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

SRCAP Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for SRCAP from the Pathway Commons Protein-Protein Interactions dataset.

SRCAP-associated chromatin remodeling complex Gene Set

From CORUM Protein Complexes

proteins in the SRCAP-associated chromatin remodeling complex protein complex from the CORUM Protein Complexes dataset.