Name

ST6GALNAC1 Gene

ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1

Glycosylation of proteins affects cell-cell interaction, interactions with the matrix, and the functions of intracellular molecules. ST6GALNAC1 transfers a sialic acid, N-acetylneuraminic acid (NeuAc), in an alpha-2,6 linkage to O-linked GalNAc residues. The cancer-associated sialyl-Tn (sTn) antigen is formed by ST6GALNAC1-catalyzed sialylation of GalNAc residues on mucins (Ikehara et al., 1999 [PubMed 10536037]; Sewell et al., 2006 [PubMed 16319059]).[supplied by OMIM, Mar 2008]

st6galnac1 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term st6galnac1 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

ST6GALNAC1 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for ST6GALNAC1 from the Pathway Commons Protein-Protein Interactions dataset.