Name

STARD5 Gene

StAR-related lipid transfer (START) domain containing 5

Cholesterol homeostasis is regulated, at least in part, by sterol regulatory element (SRE)-binding proteins (e.g., SREBP1; MIM 184756) and by liver X receptors (e.g., LXRA; MIM 602423). Upon sterol depletion, LXRs are inactive and SREBPs are cleaved, after which they bind promoter SREs and activate genes involved in cholesterol biosynthesis and uptake. Sterol transport is mediated by vesicles or by soluble protein carriers, such as steroidogenic acute regulatory protein (STAR; MIM 600617). STAR is homologous to a family of proteins containing a 200- to 210-amino acid STAR-related lipid transfer (START) domain, including STARD5 (Soccio et al., 2002 [PubMed 12011452]).[supplied by OMIM, Mar 2008]

stard5 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term stard5 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

STARD5 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for STARD5 from the Pathway Commons Protein-Protein Interactions dataset.