Harmonizome

serine/threonine kinase 11

This gene, which encodes a member of the serine/threonine kinase family, regulates cell polarity and functions as a tumor suppressor. Mutations in this gene have been associated with Peutz-Jeghers syndrome, an autosomal dominant disorder characterized by the growth of polyps in the gastrointestinal tract, pigmented macules on the skin and mouth, and other neoplasms. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq, Jul 2008]

serine/threonine kinase 11 interacting protein

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term stk11 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

From KEA Substrates of Kinases

substrates of the kinase STK11 from the curated KEA Substrates of Kinases dataset.

From Pathway Commons Protein-Protein Interactions

interacting proteins for STK11 from the Pathway Commons Protein-Protein Interactions dataset.

From PhosphoSitePlus Substrates of Kinases

substrates of the kinase STK11 from the curated PhosphoSitePlus Substrates of Kinases dataset.

From GEO Signatures of Differentially Expressed Genes for Kinase Perturbations

genes differentially expressed following the STK11_knockout_278_GSE34866 kinase perturbation from the GEO Signatures of Differentially Expressed Genes for Kinase Perturbations dataset.

From NURSA Protein Complexes

proteins in the BL8936 (STK11IP) protein complex recovered by IP-MS from the NURSA Protein Complexes dataset.

From Pathway Commons Protein-Protein Interactions

interacting proteins for STK11IP from the Pathway Commons Protein-Protein Interactions dataset.