Name

TDP2 Gene

tyrosyl-DNA phosphodiesterase 2

This gene encodes a member of a superfamily of divalent cation-dependent phosphodiesterases. The encoded protein associates with CD40, tumor necrosis factor (TNF) receptor-75 and TNF receptor associated factors (TRAFs), and inhibits nuclear factor-kappa-B activation. This protein has sequence and structural similarities with APE1 endonuclease, which is involved in both DNA repair and the activation of transcription factors. [provided by RefSeq, Jul 2008]

tdp2 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term tdp2 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

TDP2 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for TDP2 from the Pathway Commons Protein-Protein Interactions dataset.