Name

TEK Gene

TEK tyrosine kinase, endothelial

This gene encodes a receptor that belongs to the protein tyrosine kinase Tie2 family. The encoded protein possesses a unique extracellular region that contains two immunoglobulin-like domains, three epidermal growth factor (EGF)-like domains and three fibronectin type III repeats. The ligand angiopoietin-1 binds to this receptor and mediates a signaling pathway that functions in embryonic vascular development. Mutations in this gene are associated with inherited venous malformations of the skin and mucous membranes. Alternative splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Feb 2014]

TEKT1 Gene

tektin 1

This gene product belongs to the tektin family of proteins. Tektins comprise a family of filament-forming proteins that are coassembled with tubulins to form ciliary and flagellar microtubules. This gene is predominantly expressed in the testis and in mouse, tektin 1 mRNA was localized to the spermatocytes and round spermatids in the seminiferous tubules, indicating that it may play a role in spermatogenesis. [provided by RefSeq, Jul 2008]

TEKT3 Gene

tektin 3

This gene product belongs to the tektin family of proteins. Tektins comprise a family of filament-forming proteins that are coassembled with tubulins to form ciliary and flagellar microtubules. The exact function of this gene is not known. [provided by RefSeq, Jul 2008]

TEKT2 Gene

tektin 2 (testicular)

This gene product belongs to the tektin family of proteins. Tektins comprise a family of filament-forming proteins that are coassembled with tubulins to form ciliary and flagellar microtubules. This gene is expressed in the testis and its protein is localized to the flagella of the sperms, indicating that it may play a role in spermatogenesis. [provided by RefSeq, Jul 2008]

TEKT5 Gene

tektin 5

TEKT4 Gene

tektin 4

TEKT4P3 Gene

tektin 4 pseudogene 3

TEKT4P2 Gene

tektin 4 pseudogene 2

TEKT4P1 Gene

tektin 4 pseudogene 1

TEK Gene Set

From KEA Substrates of Kinases

substrates of the kinase TEK from the curated KEA Substrates of Kinases dataset.

TEK Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for TEK from the Pathway Commons Protein-Protein Interactions dataset.

TEK Gene Set

From PhosphoSitePlus Substrates of Kinases

substrates of the kinase TEK from the curated PhosphoSitePlus Substrates of Kinases dataset.

tektin Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term tektin in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

TEK_knockdown_122_GSE27869 Gene Set

From GEO Signatures of Differentially Expressed Genes for Kinase Perturbations

genes differentially expressed following the TEK_knockdown_122_GSE27869 kinase perturbation from the GEO Signatures of Differentially Expressed Genes for Kinase Perturbations dataset.

Tektin Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Tektin protein domain from the InterPro Predicted Protein Domain Annotations dataset.

TEKT4 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for TEKT4 from the Pathway Commons Protein-Protein Interactions dataset.

TEKT3 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for TEKT3 from the Pathway Commons Protein-Protein Interactions dataset.