Name

TGFBR1 Gene

transforming growth factor, beta receptor 1

The protein encoded by this gene forms a heteromeric complex with type II TGF-beta receptors when bound to TGF-beta, transducing the TGF-beta signal from the cell surface to the cytoplasm. The encoded protein is a serine/threonine protein kinase. Mutations in this gene have been associated with Loeys-Dietz aortic aneurysm syndrome (LDAS). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]

tgfbr1 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term tgfbr1 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

TGFBR1 Gene Set

From Hub Proteins Protein-Protein Interactions

interacting proteins for hub protein TGFBR1 from the curated Hub Proteins Protein-Protein Interactions dataset.

TGFBR1 Gene Set

From KEA Substrates of Kinases

substrates of the kinase TGFBR1 from the curated KEA Substrates of Kinases dataset.

TGFBR1 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for TGFBR1 from the Pathway Commons Protein-Protein Interactions dataset.

TGFBR1 Gene Set

From PhosphoSitePlus Substrates of Kinases

substrates of the kinase TGFBR1 from the curated PhosphoSitePlus Substrates of Kinases dataset.

tgfbr1pten Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term tgfbr1pten in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

tgfbr1smad23 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term tgfbr1smad23 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

tgfbr16a Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term tgfbr16a in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

tgfbr12 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term tgfbr12 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

TGFBR1_activemutant_291_GSE14523 Gene Set

From GEO Signatures of Differentially Expressed Genes for Kinase Perturbations

genes differentially expressed following the TGFBR1_activemutant_291_GSE14523 kinase perturbation from the GEO Signatures of Differentially Expressed Genes for Kinase Perturbations dataset.

TGFBR1_knockdown_102_GSE27869 Gene Set

From GEO Signatures of Differentially Expressed Genes for Kinase Perturbations

genes differentially expressed following the TGFBR1_knockdown_102_GSE27869 kinase perturbation from the GEO Signatures of Differentially Expressed Genes for Kinase Perturbations dataset.

TGFBR1 KD Mutants in Cancer Gene Set

From Reactome Pathways

proteins participating in the TGFBR1 KD Mutants in Cancer pathway from the Reactome Pathways dataset.

Loss of Function of TGFBR1 in Cancer Gene Set

From Reactome Pathways

proteins participating in the Loss of Function of TGFBR1 in Cancer pathway from the Reactome Pathways dataset.

TGFBR1 LBD Mutants in Cancer Gene Set

From Reactome Pathways

proteins participating in the TGFBR1 LBD Mutants in Cancer pathway from the Reactome Pathways dataset.