transforming growth factor, beta receptor III

This locus encodes the transforming growth factor (TGF)-beta type III receptor. The encoded receptor is a membrane proteoglycan that often functions as a co-receptor with other TGF-beta receptor superfamily members. Ectodomain shedding produces soluble TGFBR3, which may inhibit TGFB signaling. Decreased expression of this receptor has been observed in various cancers. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.[provided by RefSeq, Sep 2010]


transforming growth factor, beta receptor III-like

tgfbr3 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term tgfbr3 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

TGFBR3 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for TGFBR3 from the Pathway Commons Protein-Protein Interactions dataset.