Name

TINF2 Gene

TERF1 (TRF1)-interacting nuclear factor 2

This gene encodes one of the proteins of the shelterin, or telosome, complex which protects telomeres by allowing the cell to distinguish between telomeres and regions of DNA damage. The protein encoded by this gene is a critical part of shelterin; it interacts with the three DNA-binding proteins of the shelterin complex, and it is important for assembly of the complex. Mutations in this gene cause dyskeratosis congenita (DKC), an inherited bone marrow failure syndrome. [provided by RefSeq, Mar 2010]

tinf2 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term tinf2 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

TINF2 Gene Set

From MSigDB Cancer Gene Co-expression Modules

co-expressed genes for TINF2 from the MSigDB Cancer Gene Co-expression Modules dataset.

TINF2 Gene Set

From NURSA Protein-Protein Interactions

interacting proteins for TINF2 from the NURSA Protein-Protein Interactions dataset.

TINF2 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for TINF2 from the Pathway Commons Protein-Protein Interactions dataset.