Name

TJP2 Gene

tight junction protein 2

This gene encodes a zonula occluden that is a member of the membrane-associated guanylate kinase homolog family. The encoded protein functions as a component of the tight junction barrier in epithelial and endothelial cells and is necessary for proper assembly of tight junctions. Mutations in this gene have been identified in patients with hypercholanemia, and genomic duplication of a 270 kb region including this gene causes autosomal dominant deafness-51. Alternatively spliced transcripts encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011]

tjp2 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term tjp2 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

TJP2 Gene Set

From NURSA Protein-Protein Interactions

interacting proteins for TJP2 from the NURSA Protein-Protein Interactions dataset.

TJP2 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for TJP2 from the Pathway Commons Protein-Protein Interactions dataset.