Name

TLE3 Gene

transducin-like enhancer of split 3

This gene encodes a transcriptional co-repressor protein that belongs to the transducin-like enhancer family of proteins. The members of this family function in the Notch signaling pathway that regulates determination of cell fate during development. Expression of this gene has been associated with a favorable outcome to chemotherapy with taxanes for ovarian carcinoma. Alternate splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Sep 2013]

tle3 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term tle3 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

TLE3 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for TLE3 from the Pathway Commons Protein-Protein Interactions dataset.

tle3-aes complex Gene Set

From COMPARTMENTS Curated Protein Localization Evidence Scores

proteins localized to the tle3-aes complex cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.

Tle3-Aes complex Gene Set

From CORUM Protein Complexes

proteins in the Tle3-Aes complex protein complex from the CORUM Protein Complexes dataset.

tle3-aes complex Gene Set

From GO Cellular Component Annotations

proteins localized to the tle3-aes complex cellular component from the curated GO Cellular Component Annotations dataset.