Name

TLL1 Gene

tolloid-like 1

This gene encodes an astacin-like, zinc-dependent, metalloprotease that belongs to the peptidase M12A family. This protease processes procollagen C-propeptides, such as chordin, pro-biglycan and pro-lysyl oxidase. Studies in mice suggest that this gene plays multiple roles in the development of mammalian heart, and is essential for the formation of the interventricular septum. Allelic variants of this gene are associated with atrial septal defect type 6. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2011]

tll1 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term tll1 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

TLL1 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for TLL1 from the Pathway Commons Protein-Protein Interactions dataset.