Name

TLR1 Gene

toll-like receptor 1

The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is ubiquitously expressed, and at higher levels than other TLR genes. Different length transcripts presumably resulting from use of alternative polyadenylation site, and/or from alternative splicing, have been noted for this gene. [provided by RefSeq, Jul 2008]

TLR10 Gene

toll-like receptor 10

The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is most highly expressed in lymphoid tissues such as spleen, lymph node, thymus, and tonsil. Multiple alternatively spliced transcript variants which encode different protein isoforms have been found for this gene. [provided by RefSeq, Aug 2010]

TLR12P Gene

toll-like receptor 12, pseudogene

tlr1 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term tlr1 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

TLR1 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for TLR1 from the Pathway Commons Protein-Protein Interactions dataset.

tlr12 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term tlr12 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

tlr12mediated Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term tlr12mediated in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

tlr1016 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term tlr1016 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

tlr1tlr2 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term tlr1tlr2 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

tlr10 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term tlr10 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

tlr16 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term tlr16 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

tlr10tlr1tlr6 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term tlr10tlr1tlr6 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

toll-like receptor tlr1:tlr2 signaling pathway Gene Set

From GO Biological Process Annotations

genes participating in the toll-like receptor tlr1:tlr2 signaling pathway biological process from the curated GO Biological Process Annotations dataset.

TLR10 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for TLR10 from the Pathway Commons Protein-Protein Interactions dataset.

Toll Like Receptor TLR1:TLR2 Cascade Gene Set

From Reactome Pathways

proteins participating in the Toll Like Receptor TLR1:TLR2 Cascade pathway from the Reactome Pathways dataset.

Toll Like Receptor 10 (TLR10) Cascade Gene Set

From Reactome Pathways

proteins participating in the Toll Like Receptor 10 (TLR10) Cascade pathway from the Reactome Pathways dataset.