Name

TLR7 Gene

toll-like receptor 7

The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is predominantly expressed in lung, placenta, and spleen, and lies in close proximity to another family member, TLR8, on chromosome X. [provided by RefSeq, Jul 2008]

tlr7 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term tlr7 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

TLR7 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for TLR7 from the Pathway Commons Protein-Protein Interactions dataset.

tlr78mediated Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term tlr78mediated in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

tlr79mediated Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term tlr79mediated in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

tlr7dependent Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term tlr7dependent in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

tlr7stimulated Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term tlr7stimulated in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

tlr79dependent Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term tlr79dependent in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

tlr78 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term tlr78 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

tlr7induced Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term tlr7induced in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

tlr79 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term tlr79 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

tlr78induced Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term tlr78induced in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation Gene Set

From Reactome Pathways

proteins participating in the TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation pathway from the Reactome Pathways dataset.

TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling Gene Set

From Reactome Pathways

proteins participating in the TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling pathway from the Reactome Pathways dataset.

IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation Gene Set

From Reactome Pathways

proteins participating in the IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation pathway from the Reactome Pathways dataset.

Toll Like Receptor 7/8 (TLR7/8) Cascade Gene Set

From Reactome Pathways

proteins participating in the Toll Like Receptor 7/8 (TLR7/8) Cascade pathway from the Reactome Pathways dataset.

IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation Gene Set

From Reactome Pathways

proteins participating in the IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation pathway from the Reactome Pathways dataset.