Name

TMED1 Gene

transmembrane emp24 protein transport domain containing 1

This gene belongs to the TMED (transmembrane emp24 domain-containing) protein family, which is involved in the vesicular trafficking of proteins. The protein encoded by this gene was identified by its interaction with interleukin 1 receptor-like 1 (IL1RL1) and may play a role in innate immunity. This protein lacks any similarity to other interleukin 1 ligands. Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jul 2013]

TMED10P1 Gene

transmembrane emp24-like trafficking protein 10 (yeast) pseudogene 1

TMED10P2 Gene

transmembrane emp24-like trafficking protein 10 (yeast) pseudogene 2

TMED10 Gene

transmembrane emp24-like trafficking protein 10 (yeast)

This gene is a member of the EMP24/GP25L/p24 family and encodes a protein with a GOLD domain. This type I membrane protein is localized to the plasma membrane and golgi cisternae and is involved in vesicular protein trafficking. The protein is also a member of a heteromeric secretase complex and regulates the complex's gamma-secretase activity without affecting its epsilon-secretase activity. Mutations in this gene have been associated with early-onset familial Alzheimer's disease. This gene has a pseudogene on chromosome 8. [provided by RefSeq, Jul 2008]

TMED11P Gene

transmembrane emp24 protein transport domain containing 11, pseudogene

tmed1 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term tmed1 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

TMED1 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for TMED1 from the Pathway Commons Protein-Protein Interactions dataset.

TMED10 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for TMED10 from the Pathway Commons Protein-Protein Interactions dataset.