Name

TMEFF2 Gene

transmembrane protein with EGF-like and two follistatin-like domains 2

This gene encodes a member of the tomoregulin family of transmembrane proteins. This protein has been shown to function as both an oncogene and a tumor suppressor depending on the cellular context and may regulate prostate cancer cell invasion. Multiple soluble forms of this protein have been identified that arise from both an alternative splice variant and ectodomain shedding. Additionally, this gene has been found to be hypermethylated in multiple cancer types. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2015]

tmeff2 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term tmeff2 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

TMEFF2 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for TMEFF2 from the Pathway Commons Protein-Protein Interactions dataset.