tumor necrosis factor receptor superfamily, member 10a

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL), and thus transduces cell death signal and induces cell apoptosis. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. [provided by RefSeq, Jul 2008]

tnfrsf10a Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term tnfrsf10a in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

TNFRSF10A Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for TNFRSF10A from the Pathway Commons Protein-Protein Interactions dataset.