Name

TNFRSF10B Gene

tumor necrosis factor receptor superfamily, member 10b

The protein encoded by this gene is a member of the TNF-receptor superfamily, and contains an intracellular death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces an apoptosis signal. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. Two transcript variants encoding different isoforms and one non-coding transcript have been found for this gene. [provided by RefSeq, Mar 2009]

tnfrsf10b Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term tnfrsf10b in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

TNFRSF10B Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for TNFRSF10B from the Pathway Commons Protein-Protein Interactions dataset.