Name

TNFRSF9 Gene

tumor necrosis factor receptor superfamily, member 9

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contributes to the clonal expansion, survival, and development of T cells. It can also induce proliferation in peripheral monocytes, enhance T cell apoptosis induced by TCR/CD3 triggered activation, and regulate CD28 co-stimulation to promote Th1 cell responses. The expression of this receptor is induced by lymphocyte activation. TRAF adaptor proteins have been shown to bind to this receptor and transduce the signals leading to activation of NF-kappaB. [provided by RefSeq, Jul 2008]

tnfrsf9 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term tnfrsf9 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

TNFRSF9 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for TNFRSF9 from the Pathway Commons Protein-Protein Interactions dataset.