Name

TPH1 Gene

tryptophan hydroxylase 1

This gene encodes a member of the aromatic amino acid hydroxylase family. The encoded protein catalyzes the first and rate limiting step in the biosynthesis of serotonin, an important hormone and neurotransmitter. Mutations in this gene have been associated with an elevated risk for a variety of diseases and disorders, including schizophrenia, somatic anxiety, anger-related traits, bipolar disorder, suicidal behavior, addictions, and others.[provided by RefSeq, Apr 2009]

tph1 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term tph1 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

TPH1 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for TPH1 from the Pathway Commons Protein-Protein Interactions dataset.