Name

UBA2 Gene

ubiquitin-like modifier activating enzyme 2

Posttranslational modification of proteins by the addition of the small protein SUMO (see SUMO1; MIM 601912), or sumoylation, regulates protein structure and intracellular localization. SAE1 (MIM 613294) and UBA2 form a heterodimer that functions as a SUMO-activating enzyme for the sumoylation of proteins (Okuma et al., 1999 [PubMed 9920803]).[supplied by OMIM, Mar 2010]

uba2 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term uba2 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

UBA2 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for UBA2 from the Pathway Commons Protein-Protein Interactions dataset.

SUA1-UBA2 complex Gene Set

From CORUM Protein Complexes

proteins in the SUA1-UBA2 complex protein complex from the CORUM Protein Complexes dataset.

SUMO1-SUA1-UBA2 complex Gene Set

From CORUM Protein Complexes

proteins in the SUMO1-SUA1-UBA2 complex protein complex from the CORUM Protein Complexes dataset.

SUMO is conjugated to E1 (UBA2:SAE1) Gene Set

From Reactome Pathways

proteins participating in the SUMO is conjugated to E1 (UBA2:SAE1) pathway from the Reactome Pathways dataset.