Name

UGT1A9 Gene

UDP glucuronosyltransferase 1 family, polypeptide A9

This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. The enzyme encoded by this gene is active on phenols. [provided by RefSeq, Jul 2008]

ugt1a9 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term ugt1a9 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

UGT1A9 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for UGT1A9 from the Pathway Commons Protein-Protein Interactions dataset.

ugt1a922 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term ugt1a922 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.