VAV3 Gene

vav 3 guanine nucleotide exchange factor

This gene is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. This gene product acts as a GEF preferentially for RhoG, RhoA, and to a lesser extent, RAC1, and it associates maximally with the nucleotide-free states of these GTPases. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]

VAV3-AS1 Gene

VAV3 antisense RNA 1

vav3 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term vav3 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

VAV3 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for VAV3 from the Pathway Commons Protein-Protein Interactions dataset.