zinc finger, FYVE domain containing 27
This gene encodes a protein with several transmembrane domains, a Rab11-binding domain and a lipid-binding FYVE finger domain. The encoded protein appears to promote neurite formation. A mutation in this gene has been reported to be associated with hereditary spastic paraplegia, however the pathogenicity of the mutation, which may simply represent a polymorphism, is unclear. [provided by RefSeq, Mar 2010]
ZFYVE27 Gene Set
interacting proteins for ZFYVE27 from the Pathway Commons Protein-Protein Interactions dataset.