A1BG

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: The protein encoded by this gene is a plasma glycoprotein of unknown function. The protein shows sequence similarity to the variable regions of some immunoglobulin supergene family member proteins. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1exogenous drug catabolic process (GO:0042738)8.77738200
2omega-hydroxylase P450 pathway (GO:0097267)8.15141215
3epoxygenase P450 pathway (GO:0019373)7.84689291
4erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222)7.80150608
5L-phenylalanine catabolic process (GO:0006559)7.80150608
6erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221)7.41832323
7L-phenylalanine metabolic process (GO:0006558)7.41832323
8triglyceride-rich lipoprotein particle remodeling (GO:0034370)7.04094503
9aromatic amino acid family catabolic process (GO:0009074)6.70824544
10high-density lipoprotein particle remodeling (GO:0034375)6.21824550
11oxidative demethylation (GO:0070989)6.19276658
12indole-containing compound catabolic process (GO:0042436)5.74169115
13indolalkylamine catabolic process (GO:0046218)5.74169115
14tryptophan catabolic process (GO:0006569)5.74169115
15alpha-linolenic acid metabolic process (GO:0036109)5.68262638
16kynurenine metabolic process (GO:0070189)5.67470198
17negative regulation of fibrinolysis (GO:0051918)5.63677527
18sulfur amino acid catabolic process (GO:0000098)5.57213720
19cysteine metabolic process (GO:0006534)5.56682842
20urea cycle (GO:0000050)5.54361286
21urea metabolic process (GO:0019627)5.54361286
22bile acid biosynthetic process (GO:0006699)5.49349669
23peptidyl-glutamic acid carboxylation (GO:0017187)5.46584236
24protein carboxylation (GO:0018214)5.46584236
25serine family amino acid catabolic process (GO:0009071)5.45304536
26regulation of cholesterol esterification (GO:0010872)5.44517027
27tryptophan metabolic process (GO:0006568)5.44511440
28glyoxylate metabolic process (GO:0046487)5.39897723
29regulation of fibrinolysis (GO:0051917)5.31968308
30reverse cholesterol transport (GO:0043691)5.27701539
31regulation of plasminogen activation (GO:0010755)5.18491499
32protein-lipid complex remodeling (GO:0034368)5.15318251
33macromolecular complex remodeling (GO:0034367)5.15318251
34plasma lipoprotein particle remodeling (GO:0034369)5.15318251
35S-adenosylmethionine metabolic process (GO:0046500)5.11090939
36negative regulation of sterol transport (GO:0032372)5.10241352
37negative regulation of cholesterol transport (GO:0032375)5.10241352
38nitrogen cycle metabolic process (GO:0071941)5.09230469
39bile acid metabolic process (GO:0008206)5.05586653
40phospholipid efflux (GO:0033700)5.02558259
41tyrosine metabolic process (GO:0006570)4.99982606
42protein activation cascade (GO:0072376)4.92877408
43cellular ketone body metabolic process (GO:0046950)4.88932711
44ethanol metabolic process (GO:0006067)4.87705739
45aromatic amino acid family metabolic process (GO:0009072)4.86288581
46plasma lipoprotein particle clearance (GO:0034381)4.83330931
47phenylpropanoid metabolic process (GO:0009698)4.73515193
48acylglycerol homeostasis (GO:0055090)4.70166697
49triglyceride homeostasis (GO:0070328)4.70166697
50alpha-amino acid catabolic process (GO:1901606)4.69406901
51low-density lipoprotein particle remodeling (GO:0034374)4.67462066
52complement activation (GO:0006956)4.66036214
53regulation of triglyceride catabolic process (GO:0010896)4.64435086
54amino-acid betaine metabolic process (GO:0006577)4.63575067
55alkaloid metabolic process (GO:0009820)4.62607398
56homocysteine metabolic process (GO:0050667)4.58321654
57complement activation, classical pathway (GO:0006958)4.56479025
58glycine metabolic process (GO:0006544)4.55780833
59imidazole-containing compound metabolic process (GO:0052803)4.46732105
60drug catabolic process (GO:0042737)4.46495068
61cholesterol efflux (GO:0033344)4.44314566
62fatty acid beta-oxidation using acyl-CoA oxidase (GO:0033540)4.43888618
63bile acid and bile salt transport (GO:0015721)4.43037763
64regulation of protein activation cascade (GO:2000257)4.37542608
65acute-phase response (GO:0006953)4.35626222
66regulation of humoral immune response (GO:0002920)4.33999833
67glutamate metabolic process (GO:0006536)4.33097729
68lysine catabolic process (GO:0006554)4.32306432
69lysine metabolic process (GO:0006553)4.32306432
70plasma lipoprotein particle assembly (GO:0034377)4.32186988
71cellular amino acid catabolic process (GO:0009063)4.31788893
72complement activation, alternative pathway (GO:0006957)4.31747889
73ketone body metabolic process (GO:1902224)4.23019168
74negative regulation of hemostasis (GO:1900047)4.21929954
75negative regulation of blood coagulation (GO:0030195)4.21929954
76cytolysis (GO:0019835)4.21888455
77serine family amino acid metabolic process (GO:0009069)4.21479065
78cellular glucuronidation (GO:0052695)4.20611395
79serine family amino acid biosynthetic process (GO:0009070)4.18097379
80benzene-containing compound metabolic process (GO:0042537)4.09652995
81indolalkylamine metabolic process (GO:0006586)4.08357364
82short-chain fatty acid metabolic process (GO:0046459)4.07906169
83negative regulation of lipase activity (GO:0060192)4.07618612
84negative regulation of protein activation cascade (GO:2000258)4.07401107
85ethanol oxidation (GO:0006069)4.07218632
86coenzyme catabolic process (GO:0009109)4.06710203
87drug metabolic process (GO:0017144)4.06299589
88arginine metabolic process (GO:0006525)4.03997294
89cellular biogenic amine catabolic process (GO:0042402)4.03899825
90amine catabolic process (GO:0009310)4.03899825
91aldehyde catabolic process (GO:0046185)4.01600830
92dicarboxylic acid biosynthetic process (GO:0043650)4.01349321
93cellular modified amino acid catabolic process (GO:0042219)4.00194220
94very-low-density lipoprotein particle assembly (GO:0034379)3.99854471
95disruption of cells of other organism involved in symbiotic interaction (GO:0051818)3.98612816
96killing of cells in other organism involved in symbiotic interaction (GO:0051883)3.98612816
97regulation of complement activation (GO:0030449)3.93961319
98protein-lipid complex assembly (GO:0065005)3.89242583
99fibrinolysis (GO:0042730)3.88737345
100plasma lipoprotein particle organization (GO:0071827)3.86472590
101positive regulation of lipid catabolic process (GO:0050996)3.84650184
102negative regulation of coagulation (GO:0050819)3.83355739
103organic acid catabolic process (GO:0016054)3.81538788
104carboxylic acid catabolic process (GO:0046395)3.81538788
105positive regulation of hemostasis (GO:1900048)3.81412018
106positive regulation of blood coagulation (GO:0030194)3.81412018
107cholesterol homeostasis (GO:0042632)3.80717544
108flavonoid metabolic process (GO:0009812)3.78220474
109blood coagulation, intrinsic pathway (GO:0007597)3.75930858
110positive regulation of lipoprotein lipase activity (GO:0051006)3.75918354
111positive regulation of triglyceride lipase activity (GO:0061365)3.75918354
112positive regulation of heterotypic cell-cell adhesion (GO:0034116)3.75015749
113sterol homeostasis (GO:0055092)3.74383208
114negative regulation of wound healing (GO:0061045)3.74280466
115uronic acid metabolic process (GO:0006063)3.71826208
116glucuronate metabolic process (GO:0019585)3.71826208
117cofactor catabolic process (GO:0051187)3.65963285
118regulation of cholesterol homeostasis (GO:2000188)3.65283833
119protein-lipid complex subunit organization (GO:0071825)3.64486445
120phospholipid homeostasis (GO:0055091)3.61797715
121regulation of bile acid biosynthetic process (GO:0070857)3.59902382
122arginine catabolic process (GO:0006527)3.59727735
123opsonization (GO:0008228)3.58830378
124monocarboxylic acid catabolic process (GO:0072329)3.54787174
125lipoprotein metabolic process (GO:0042157)3.54504878
126positive regulation of fatty acid beta-oxidation (GO:0032000)3.53263361
127intestinal cholesterol absorption (GO:0030299)3.47655700
128positive regulation of coagulation (GO:0050820)3.45456208
129positive regulation of fatty acid biosynthetic process (GO:0045723)3.44558933
130peptidyl-glutamic acid modification (GO:0018200)3.40335881
131negative regulation of complement activation (GO:0045916)3.38285398

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1* RXR_22158963_ChIP-Seq_LIVER_Mouse8.46586189
2* PPARA_22158963_ChIP-Seq_LIVER_Mouse7.14469935
3EGR1_23403033_ChIP-Seq_LIVER_Mouse6.74607461
4* LXR_22158963_ChIP-Seq_LIVER_Mouse6.54834692
5FOXO1_23066095_ChIP-Seq_LIVER_Mouse5.12722622
6CEBPA_23403033_ChIP-Seq_LIVER_Mouse5.08676432
7PPARG_19300518_ChIP-PET_3T3-L1_Mouse5.03197432
8CEBPB_23403033_ChIP-Seq_LIVER_Mouse3.90032340
9NR1I2_20693526_ChIP-Seq_LIVER_Mouse3.87474336
10ZNF274_21170338_ChIP-Seq_K562_Hela2.20446226
11TCF7L2_21901280_ChIP-Seq_H4IIE_Rat2.03792443
12ESR1_17901129_ChIP-ChIP_LIVER_Mouse11.7980826
13HNF4A_19761587_ChIP-ChIP_CACO-2_Human1.96115959
14TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.85320315
15VDR_22108803_ChIP-Seq_LS180_Human1.79540395
16GBX2_23144817_ChIP-Seq_PC3_Human1.78300981
17NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.71598732
18IGF1R_20145208_ChIP-Seq_DFB_Human1.65534623
19POU3F2_20337985_ChIP-ChIP_501MEL_Human1.65037180
20GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.60339555
21FOXA2_19822575_ChIP-Seq_HepG2_Human1.59583934
22HTT_18923047_ChIP-ChIP_STHdh_Human1.56251250
23IRF1_19129219_ChIP-ChIP_H3396_Human1.54469764
24CLOCK_20551151_ChIP-Seq_293T_Human1.53904963
25ER_23166858_ChIP-Seq_MCF-7_Human1.48533217
26CTBP1_25329375_ChIP-Seq_LNCAP_Human1.45515057
27ETV2_25802403_ChIP-Seq_MESCs_Mouse1.38023942
28* HNF4A_19822575_ChIP-Seq_HepG2_Human1.37204258
29ZFP57_27257070_Chip-Seq_ESCs_Mouse1.33179390
30THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.28628648
31CTBP2_25329375_ChIP-Seq_LNCAP_Human1.27824270
32GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.23017881
33PIAS1_25552417_ChIP-Seq_VCAP_Human1.20578915
34NFE2_27457419_Chip-Seq_LIVER_Mouse1.18379232
35MYC_19829295_ChIP-Seq_ESCs_Human1.18014029
36STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.15701871
37RXRA_24833708_ChIP-Seq_LIVER_Mouse1.15435024
38ESR1_15608294_ChIP-ChIP_MCF-7_Human1.14935777
39IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.14077595
40PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.11553347
41EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.10475483
42GATA1_22025678_ChIP-Seq_K562_Human1.09693285
43FOXA1_27270436_Chip-Seq_PROSTATE_Human1.09621082
44FOXA1_25329375_ChIP-Seq_VCAP_Human1.09621082
45NANOG_19829295_ChIP-Seq_ESCs_Human1.08541051
46SOX2_19829295_ChIP-Seq_ESCs_Human1.08541051
47FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.07431827
48EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.05622866
49CBP_20019798_ChIP-Seq_JUKART_Human1.05254723
50IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.05254723
51NCOR_22424771_ChIP-Seq_293T_Human1.05204730
52PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.04171883
53UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.03920699
54* ERA_21632823_ChIP-Seq_H3396_Human1.02689278
55GATA3_21878914_ChIP-Seq_MCF-7_Human1.02613427
56EZH2_27294783_Chip-Seq_NPCs_Mouse1.02598256
57RAC3_21632823_ChIP-Seq_H3396_Human1.01054487
58LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.00953621
59PCGF2_27294783_Chip-Seq_NPCs_Mouse1.00865238
60KLF5_20875108_ChIP-Seq_MESCs_Mouse0.99824756
61ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse0.99286871
62SUZ12_27294783_Chip-Seq_NPCs_Mouse0.99176996
63STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse0.98893513
64P300_19829295_ChIP-Seq_ESCs_Human0.98681888
65EBNA1_20929547_Chip-Seq_RAJI-cells_Human0.97507935
66FOXH1_21741376_ChIP-Seq_EPCs_Human0.95984738
67AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human0.95826036
68ZNF652_21678463_ChIP-ChIP_ZR75-1_Human0.94562606
69TCF4_22108803_ChIP-Seq_LS180_Human0.93455298
70ZNF263_19887448_ChIP-Seq_K562_Human0.92681195
71CRX_20693478_ChIP-Seq_RETINA_Mouse0.92651013
72OCT4_20526341_ChIP-Seq_ESCs_Human0.92580971
73PHF8_20622853_ChIP-Seq_HELA_Human0.92185298
74REST_21632747_ChIP-Seq_MESCs_Mouse0.92045865
75STAT3_23295773_ChIP-Seq_U87_Human0.91752233
76FLI1_27457419_Chip-Seq_LIVER_Mouse0.91436494
77AR_25329375_ChIP-Seq_VCAP_Human0.91272801
78TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse0.90915113
79NANOG_20526341_ChIP-Seq_ESCs_Human0.89716196
80TP53_22573176_ChIP-Seq_HFKS_Human0.89139495
81TCF4_23295773_ChIP-Seq_U87_Human0.89131957
82FOXA1_21572438_ChIP-Seq_LNCaP_Human0.89081794
83CDX2_21074721_ChIP-Seq_CACO-2_Mouse0.87455685
84BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.87278698
85RARG_19884340_ChIP-ChIP_MEFs_Mouse0.85723314
86AUTS2_25519132_ChIP-Seq_293T-REX_Human0.85487824
87KAP1_22055183_ChIP-Seq_ESCs_Mouse0.85406166
88SMAD4_21741376_ChIP-Seq_EPCs_Human0.85054687
89DROSHA_22980978_ChIP-Seq_HELA_Human0.84594810
90HNFA_21074721_ChIP-Seq_CACO-2_Human0.84349045
91EZH2_22144423_ChIP-Seq_EOC_Human0.82953899
92MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human0.82534883
93GATA4_25053715_ChIP-Seq_YYC3_Human0.82532698
94E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse0.82333433
95SOX2_27498859_Chip-Seq_STOMACH_Mouse0.82269816
96ESRRB_18555785_ChIP-Seq_MESCs_Mouse0.82044954
97ERG_20517297_ChIP-Seq_VCAP_Human0.81711684
98FOXH1_21741376_ChIP-Seq_ESCs_Human0.81676585
99ETV1_20927104_ChIP-Seq_GIST48_Human0.81084644
100IRF8_22096565_ChIP-ChIP_GC-B_Human0.80711297
101RUNX2_22187159_ChIP-Seq_PCA_Human0.80404974
102NFYA_21822215_ChIP-Seq_K562_Human0.79931679
103POU5F1_26923725_Chip-Seq_MESODERM_Mouse0.79642486
104TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.79642486
105GATA6_21074721_ChIP-Seq_CACO-2_Human0.79556695
106NR3C1_21868756_ChIP-Seq_MCF10A_Human0.78755373
107ESR2_21235772_ChIP-Seq_MCF-7_Human0.72886173
108SREBP1_19666523_ChIP-Seq_LIVER_Mouse0.72483231
109RARA_24833708_ChIP-Seq_LIVER_Mouse0.70827591
110NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human0.70335996
111Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse0.69523241
112SREBP2_21459322_ChIP-Seq_LIVER_Mouse0.69037267
113BMI1_19503595_ChIP-Seq_MEFsC_Mouse0.68086245
114CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse0.65925171
115SALL4_18804426_ChIP-ChIP_XEN_Mouse0.63758697
116AR_21915096_ChIP-Seq_LNCaP-1F5_Human0.63647366
117NR0B1_18358816_ChIP-ChIP_MESCs_Mouse0.62795198
118LXR_22292898_ChIP-Seq_THP-1_Human0.62159586
119NFE2L2_20460467_ChIP-Seq_MEFs_Mouse0.61919660
120NRF2_20460467_ChIP-Seq_MEFs_Mouse0.61919660
121RARB_24833708_ChIP-Seq_LIVER_Mouse0.61713247
122PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse0.60290414
123RAD21_21589869_ChIP-Seq_MESCs_Mouse0.59694731
124GATA1_19941826_ChIP-Seq_K562_Human0.58505129
125RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human0.56552507
126ERG_21242973_ChIP-ChIP_JURKAT_Human0.55542047
127CEBPB_22108803_ChIP-Seq_LS180_Human0.54637022
128ESET_19884257_ChIP-Seq_ESCs_Mouse0.53612452
129STAT1_17558387_ChIP-Seq_HELA_Human0.52597466
130MYC_19915707_ChIP-ChIP_AK7_Human0.51943068
131FOXA1_25552417_ChIP-Seq_VCAP_Human0.50766429
132EGR1_19032775_ChIP-ChIP_M12_Human0.47788980
133GATA1_19941827_ChIP-Seq_MEL_Mouse0.46949075
134BCAT_22108803_ChIP-Seq_LS180_Human0.46944512
135FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human0.46242609
136P53_21459846_ChIP-Seq_SAOS-2_Human0.45322397
137CBP_21632823_ChIP-Seq_H3396_Human0.45303906
138GATA2_19941826_ChIP-Seq_K562_Human0.45164350
139PPAR_26484153_Chip-Seq_NCI-H1993_Human0.44468234
140SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.44170071
141ESR1_20079471_ChIP-ChIP_T-47D_Human0.44169319
142PPARD_23208498_ChIP-Seq_MDA-MB-231_Human0.43569154
143* PPARG_20887899_ChIP-Seq_3T3-L1_Mouse0.43159956
144TAF15_26573619_Chip-Seq_HEK293_Human0.43037534
145PBX1_22567123_ChIP-ChIP_OVCAR3_Human0.42964402
146GLI1_17442700_ChIP-ChIP_MESCs_Mouse0.42330792
147AR_20517297_ChIP-Seq_VCAP_Human0.42216254
148LUZP1_20508642_ChIP-Seq_ESCs_Mouse0.40963398
149FOXA1_26743006_Chip-Seq_LNCaP-abl_Human0.40000764
150CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse0.39909661
151MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human0.39823007
152MYC_27129775_Chip-Seq_CORNEA_Mouse0.39092770
153CDX2_20551321_ChIP-Seq_CACO-2_Human0.38079443
154STAT3_1855785_ChIP-Seq_MESCs_Mouse0.37647072
155TAF2_19829295_ChIP-Seq_ESCs_Human0.36836977
156FOXO3_23340844_ChIP-Seq_DLD1_Human0.36166704
157SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.36081796
158SMAD2/3_21741376_ChIP-Seq_ESCs_Human0.35527743
159STAT3_19079543_ChIP-ChIP_MESCs_Mouse0.34593286
160SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse0.34579197
161CTCF_27219007_Chip-Seq_Bcells_Human0.34210739
162CEBPB_26923725_Chip-Seq_MACROPHAGESS_Mouse0.34156083
163SOX3_22085726_ChIP-Seq_MUSCLE_Mouse0.33924024
164CDX2_22108803_ChIP-Seq_LS180_Human0.33914498
165GATA6_25053715_ChIP-Seq_YYC3_Human0.33901053
166ESR1_21235772_ChIP-Seq_MCF-7_Human0.33693047

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002139_abnormal_hepatobiliary_system8.56991599
2MP0005360_urolithiasis7.59142047
3MP0005085_abnormal_gallbladder_physiolo6.08788248
4MP0005365_abnormal_bile_salt6.02034518
5MP0008875_abnormal_xenobiotic_pharmacok5.38384985
6MP0003806_abnormal_nucleotide_metabolis4.26074684
7MP0010329_abnormal_lipoprotein_level3.71057871
8MP0009840_abnormal_foam_cell3.67137785
9MP0003252_abnormal_bile_duct3.51930086
10MP0005083_abnormal_biliary_tract3.36681334
11MP0003195_calcinosis3.15913287
12MP0005332_abnormal_amino_acid2.78807132
13MP0001666_abnormal_nutrient_absorption2.41321494
14MP0004019_abnormal_vitamin_homeostasis2.19890128
15MP0002118_abnormal_lipid_homeostasis2.12071498
16MP0000609_abnormal_liver_physiology2.11528041
17MP0003191_abnormal_cellular_cholesterol2.11374662
18MP0005451_abnormal_body_composition1.93810244
19MP0002138_abnormal_hepatobiliary_system1.77638050
20MP0005319_abnormal_enzyme/_coenzyme1.76111492
21MP0009697_abnormal_copulation1.68750996
22MP0003868_abnormal_feces_composition1.68689375
23MP0005584_abnormal_enzyme/coenzyme_acti1.59982196
24MP0001764_abnormal_homeostasis1.59463695
25MP0000604_amyloidosis1.31689463
26MP0003011_delayed_dark_adaptation1.26376907
27MP0003186_abnormal_redox_activity1.24183404
28MP0003705_abnormal_hypodermis_morpholog1.23649088
29MP0006292_abnormal_olfactory_placode1.21220802
30MP0009643_abnormal_urine_homeostasis1.20890062
31MP0003656_abnormal_erythrocyte_physiolo1.12060504
32MP0000598_abnormal_liver_morphology1.11542402
33MP0001986_abnormal_taste_sensitivity1.06997077
34MP0002282_abnormal_trachea_morphology1.05297549
35MP0005551_abnormal_eye_electrophysiolog1.02456200
36MP0009764_decreased_sensitivity_to1.01258959
37MP0005647_abnormal_sex_gland1.00848036
38MP0009763_increased_sensitivity_to1.00707957
39MP0005646_abnormal_pituitary_gland0.95628055
40MP0010368_abnormal_lymphatic_system0.94103426
41MP0002254_reproductive_system_inflammat0.92615107
42MP0005636_abnormal_mineral_homeostasis0.88320997
43MP0009642_abnormal_blood_homeostasis0.87186733
44MP0003329_amyloid_beta_deposits0.86615328
45MP0005408_hypopigmentation0.85738286
46MP0003879_abnormal_hair_cell0.85604568
47MP0002078_abnormal_glucose_homeostasis0.81724972
48MP0006036_abnormal_mitochondrial_physio0.81594483
49MP0008469_abnormal_protein_level0.81333982
50MP0002132_abnormal_respiratory_system0.80094355
51MP0001661_extended_life_span0.79114999
52MP0002876_abnormal_thyroid_physiology0.77777957
53MP0003690_abnormal_glial_cell0.77514244
54MP0005376_homeostasis/metabolism_phenot0.76775122
55MP0002971_abnormal_brown_adipose0.76609782
56MP0009765_abnormal_xenobiotic_induced0.75677733
57MP0004142_abnormal_muscle_tone0.75584584
58MP0009053_abnormal_anal_canal0.74188703
59MP0009785_altered_susceptibility_to0.71348778
60MP0002638_abnormal_pupillary_reflex0.69401616
61MP0005334_abnormal_fat_pad0.69149280
62MP0005084_abnormal_gallbladder_morpholo0.67642249
63MP0004043_abnormal_pH_regulation0.65797125
64MP0000639_abnormal_adrenal_gland0.65698251
65MP0005448_abnormal_energy_balance0.64381988
66MP0002822_catalepsy0.63250343
67MP0009745_abnormal_behavioral_response0.62397051
68MP0004130_abnormal_muscle_cell0.62380480
69MP0005535_abnormal_body_temperature0.60633167
70MP0005464_abnormal_platelet_physiology0.60251730
71MP0005266_abnormal_metabolism0.59086452
72MP0001756_abnormal_urination0.58170627
73MP0003646_muscle_fatigue0.56876813
74MP0005220_abnormal_exocrine_pancreas0.56825114
75MP0002837_dystrophic_cardiac_calcinosis0.56625045
76MP0001984_abnormal_olfaction0.56250743
77MP0002909_abnormal_adrenal_gland0.55662852
78MP0008874_decreased_physiological_sensi0.55307220
79MP0002249_abnormal_larynx_morphology0.55198674
80MP0005645_abnormal_hypothalamus_physiol0.53586607
81MP0003880_abnormal_central_pattern0.53005686
82MP0002102_abnormal_ear_morphology0.52749239
83MP0005248_abnormal_Harderian_gland0.52632863
84MP0003638_abnormal_response/metabolism_0.51925904
85MP0005395_other_phenotype0.51151591
86MP0002653_abnormal_ependyma_morphology0.50744840
87MP0002234_abnormal_pharynx_morphology0.50291206
88MP0001501_abnormal_sleep_pattern0.49405247
89MP0006035_abnormal_mitochondrial_morpho0.48833800
90MP0004133_heterotaxia0.48374998
91MP0003075_altered_response_to0.48016064
92MP0003718_maternal_effect0.47523613
93MP0004782_abnormal_surfactant_physiolog0.46121312
94MP0003436_decreased_susceptibility_to0.45964812
95MP0005670_abnormal_white_adipose0.45649570
96MP0001944_abnormal_pancreas_morphology0.45321191
97MP0001968_abnormal_touch/_nociception0.45205918
98MP0006082_CNS_inflammation0.44572993
99MP0008873_increased_physiological_sensi0.44554019
100MP0003953_abnormal_hormone_level0.44321808
101MP0003136_yellow_coat_color0.44225500
102MP0006276_abnormal_autonomic_nervous0.43989153
103MP0002136_abnormal_kidney_physiology0.43942710
104MP0000249_abnormal_blood_vessel0.42645157
105MP0009672_abnormal_birth_weight0.42518144
106MP0010386_abnormal_urinary_bladder0.42026382
107MP0005253_abnormal_eye_physiology0.40820416
108MP0004883_abnormal_blood_vessel0.40748292
109MP0008872_abnormal_physiological_respon0.39546887
110MP0002064_seizures0.37681810
111MP0002168_other_aberrant_phenotype0.35628094
112MP0005167_abnormal_blood-brain_barrier0.35610216
113MP0005386_behavior/neurological_phenoty0.35543867
114MP0004924_abnormal_behavior0.35543867
115MP0001243_abnormal_dermal_layer0.34945058
116MP0003633_abnormal_nervous_system0.34810148
117MP0002736_abnormal_nociception_after0.34479672
118MP0003724_increased_susceptibility_to0.34243150
119MP0002928_abnormal_bile_duct0.33806444
120MP0009115_abnormal_fat_cell0.31584038
121MP0002970_abnormal_white_adipose0.31402204
122MP0000230_abnormal_systemic_arterial0.30319025
123MP0001853_heart_inflammation0.29728402
124MP0005187_abnormal_penis_morphology0.28305431
125MP0005666_abnormal_adipose_tissue0.27618628
126MP0005595_abnormal_vascular_smooth0.27306629
127MP0005164_abnormal_response_to0.27057225
128MP0001845_abnormal_inflammatory_respons0.25112170
129MP0005166_decreased_susceptibility_to0.24387687
130MP0002090_abnormal_vision0.24382150
131MP0001881_abnormal_mammary_gland0.23918487
132MP0002269_muscular_atrophy0.23553798
133MP0002295_abnormal_pulmonary_circulatio0.20104397
134MP0005379_endocrine/exocrine_gland_phen0.17738812

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of aromatic amino acid family metabolism (HP:0004338)7.72248820
2Deep venous thrombosis (HP:0002625)7.67764457
3Intrahepatic cholestasis (HP:0001406)6.93045561
4Hypobetalipoproteinemia (HP:0003563)6.88769815
5Abnormality of monocarboxylic acid metabolism (HP:0010996)6.67559170
6Prolonged partial thromboplastin time (HP:0003645)6.49896814
7Xanthomatosis (HP:0000991)6.32429511
8Hyperlipoproteinemia (HP:0010980)6.16072190
9Joint hemorrhage (HP:0005261)5.08904624
10Hypolipoproteinemia (HP:0010981)4.97831097
11Hyperammonemia (HP:0001987)4.69524833
12Hyperglycinemia (HP:0002154)4.63397447
13Abnormality of the level of lipoprotein cholesterol (HP:0010979)4.56711589
14Abnormality of sulfur amino acid metabolism (HP:0004339)4.29434215
15Ketosis (HP:0001946)4.28920056
16Abnormality of the common coagulation pathway (HP:0010990)4.28714353
17Abnormality of methionine metabolism (HP:0010901)4.27331668
18Epidermoid cyst (HP:0200040)4.24802872
19Hyperglycinuria (HP:0003108)4.23382199
20Abnormality of serine family amino acid metabolism (HP:0010894)4.20440908
21Abnormality of glycine metabolism (HP:0010895)4.20440908
22Hypoalphalipoproteinemia (HP:0003233)4.19957314
23Abnormality of glutamine family amino acid metabolism (HP:0010902)4.18485714
24Abnormality of aspartate family amino acid metabolism (HP:0010899)4.06440483
25Hypoglycemic coma (HP:0001325)3.92886574
26Recurrent gram-negative bacterial infections (HP:0005420)3.88862803
27Hypercholesterolemia (HP:0003124)3.84755714
28Fat malabsorption (HP:0002630)3.81349089
29Abnormality of pyrimidine metabolism (HP:0004353)3.78722107
30Abnormality of the intrinsic pathway (HP:0010989)3.64275277
31Complement deficiency (HP:0004431)3.58660511
32Conjugated hyperbilirubinemia (HP:0002908)3.52342954
33Hyperbilirubinemia (HP:0002904)3.39070317
34Delayed CNS myelination (HP:0002188)3.36260522
35Abnormality of fatty-acid metabolism (HP:0004359)3.34306151
36Abnormality of long-chain fatty-acid metabolism (HP:0010964)3.28058106
37Ketoacidosis (HP:0001993)3.15549933
38Abnormality of serum amino acid levels (HP:0003112)3.08217189
39Abnormality of nucleobase metabolism (HP:0010932)3.07369081
40Fair hair (HP:0002286)3.07044125
41Vascular calcification (HP:0004934)3.01158321
42Myocardial infarction (HP:0001658)2.94548005
43Hepatocellular carcinoma (HP:0001402)2.92683303
44Metabolic acidosis (HP:0001942)2.88228607
45Steatorrhea (HP:0002570)2.75661119
46Spontaneous abortion (HP:0005268)2.75246790
47Dicarboxylic aciduria (HP:0003215)2.75077464
48Abnormality of dicarboxylic acid metabolism (HP:0010995)2.75077464
49Abnormality of purine metabolism (HP:0004352)2.71692568
50Glomerulonephritis (HP:0000099)2.68968721
51Cardiovascular calcification (HP:0011915)2.68784337
52Hypochromic microcytic anemia (HP:0004840)2.67573157
53Lethargy (HP:0001254)2.65275637
54Skin nodule (HP:0200036)2.63725798
55Abnormality of complement system (HP:0005339)2.59970588
56Malnutrition (HP:0004395)2.56979266
57Mitral stenosis (HP:0001718)2.54369240
58Hypoglycemic seizures (HP:0002173)2.46233537
59Spastic diplegia (HP:0001264)2.45601706
60Acanthocytosis (HP:0001927)2.45401514
61Menorrhagia (HP:0000132)2.42215906
62Abnormal gallbladder morphology (HP:0012437)2.40075545
63Cerebral edema (HP:0002181)2.39013248
64Irritability (HP:0000737)2.37985276
65Amyloidosis (HP:0011034)2.32585802
66Cholelithiasis (HP:0001081)2.31208691
67Bile duct proliferation (HP:0001408)2.31117520
68Abnormal biliary tract physiology (HP:0012439)2.31117520
69Gout (HP:0001997)2.30060931
70Esophageal varix (HP:0002040)2.27677799
71Neonatal onset (HP:0003623)2.20744692
72Late onset (HP:0003584)2.20035995
73Arthropathy (HP:0003040)2.19624071
74Generalized hypopigmentation of hair (HP:0011358)2.19031602
75Purpura (HP:0000979)2.16835220
76Neonatal hypoglycemia (HP:0001998)2.14308255
77Glycosuria (HP:0003076)2.14238910
78Abnormality of urine glucose concentration (HP:0011016)2.14238910
79Vomiting (HP:0002013)2.12441761
80Pancreatitis (HP:0001733)2.09644673
81Gingival bleeding (HP:0000225)2.08222888
82Abnormal gallbladder physiology (HP:0012438)2.06934885
83Cholecystitis (HP:0001082)2.06934885
84Hydroxyprolinuria (HP:0003080)2.06804683
85Abnormality of proline metabolism (HP:0010907)2.06804683
86Generalized aminoaciduria (HP:0002909)2.05991266
87Thrombophlebitis (HP:0004418)2.05515455
88Brushfield spots (HP:0001088)2.05161531
89Opisthotonus (HP:0002179)2.04181297
90Abnormality of alanine metabolism (HP:0010916)2.03633999
91Hyperalaninemia (HP:0003348)2.03633999
92Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.03633999
93Hemorrhage of the eye (HP:0011885)2.02994992
94Enlarged kidneys (HP:0000105)2.01657664
95Hyperinsulinemic hypoglycemia (HP:0000825)1.99731853
96Poikilocytosis (HP:0004447)1.98609849
97Alkalosis (HP:0001948)1.96732937
98Hyperphosphaturia (HP:0003109)1.93694309
99Nephritis (HP:0000123)1.91646075
100Hypophosphatemic rickets (HP:0004912)1.91408809
101Cerebral palsy (HP:0100021)1.90750624
102Abnormality of iron homeostasis (HP:0011031)1.90069359
103Sensorimotor neuropathy (HP:0007141)1.89797555
104Abnormality of the gallbladder (HP:0005264)1.86897436
105Abnormality of transition element cation homeostasis (HP:0011030)1.86643924
106Rickets (HP:0002748)1.86433327
107Abnormal cartilage morphology (HP:0002763)1.86338316
108Systemic lupus erythematosus (HP:0002725)1.85961938
109Hyperventilation (HP:0002883)1.85931247
110Gangrene (HP:0100758)1.82522564
111Decreased central vision (HP:0007663)1.81173085
112Pulmonary embolism (HP:0002204)1.80784053
113Status epilepticus (HP:0002133)1.79837719
114Renal cortical cysts (HP:0000803)1.78752724
115Chronic hepatic failure (HP:0100626)1.78375886
116Abnormality of the Achilles tendon (HP:0005109)1.77758933
117Congenital stationary night blindness (HP:0007642)1.77218386
118Abnormality of vitamin metabolism (HP:0100508)1.76204914
119Hypothermia (HP:0002045)1.76022867
120Reticulocytosis (HP:0001923)1.75945537
121Osteomalacia (HP:0002749)1.74218262
122Stroke (HP:0001297)1.73335199
123Pancreatic cysts (HP:0001737)1.70583053
124Reduced antithrombin III activity (HP:0001976)1.70312742
125Increased serum ferritin (HP:0003281)1.67153120
126Blue irides (HP:0000635)1.60952989
127Joint swelling (HP:0001386)1.60636216
128Acute encephalopathy (HP:0006846)1.60214918
129Mesangial abnormality (HP:0001966)1.48907173
130Potter facies (HP:0002009)1.48447102
131Facial shape deformation (HP:0011334)1.48447102
132Abnormality of the renal cortex (HP:0011035)1.46233672

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BCKDK7.45819942
2SIK15.34778472
3FGFR44.58781046
4ERN13.72662810
5PKN23.30160572
6ADRBK23.20078289
7MAP4K22.93791274
8TAOK32.92432657
9WNK32.74503610
10INSRR2.54397742
11BMPR1B2.52686419
12TLK12.36657935
13FLT32.33489091
14PIK3CG2.30711731
15MAP2K42.29168088
16TRIB32.27704782
17ZAK2.19585172
18DAPK22.19468308
19WNK42.03763168
20ACVR1B1.98641943
21MST1R1.91678762
22TYK21.84258296
23NUAK11.73583213
24PTK61.60823671
25TXK1.54070096
26KDR1.53705835
27MAPK131.51640993
28ABL21.44875514
29NTRK31.39028807
30PIK3CA1.36007539
31DYRK21.35000588
32FGFR21.33167378
33CASK1.29753443
34LATS11.28016522
35CAMKK21.26936232
36ERBB41.23486401
37MAP3K41.22950698
38PINK11.17969419
39MAPKAPK31.17139253
40TNK21.14985495
41MAPK111.14510633
42FRK1.13946677
43ADRBK11.13073171
44JAK21.12211433
45MUSK1.08232602
46MAP2K31.07186236
47TNIK1.05891871
48PRKAA21.04843445
49TBK11.00876055
50MAPK40.99213593
51IKBKB0.98779154
52GRK60.97404664
53JAK10.96745682
54MAP3K70.95235613
55EPHA40.92897251
56PRKCZ0.91450580
57OXSR10.91212582
58NEK90.88900229
59TIE10.88105384
60MAP3K110.87175794
61CDK60.86803417
62MAP3K100.86155660
63EPHB10.85345971
64CSK0.84426722
65DYRK1B0.84097841
66PRKCE0.83457578
67MAPK120.82704306
68MAP3K140.79442783
69KIT0.78636236
70MET0.77460586
71PRKACG0.76012688
72PRKG10.70501917
73MAP3K30.70090402
74CSNK1G10.69745517
75MAP2K70.68699853
76TGFBR10.68240250
77VRK10.67660486
78RIPK10.67325630
79GSK3A0.66792618
80CHUK0.65191816
81TGFBR20.65097989
82CAMK1D0.64983603
83PTK20.64472761
84MAP4K10.64453972
85RPS6KA50.64230143
86MAP2K60.63341315
87PKN10.63142436
88AKT30.62550292
89FER0.62182626
90GRK70.60847360
91CSF1R0.60389678
92SIK20.60110597
93CSNK1A10.59799764
94PRKCQ0.59525050
95NLK0.58854284
96PRKAA10.58552365
97MARK10.58383657
98CSNK1D0.58352965
99SGK30.58248832
100CSNK1G30.57740824
101MAP3K130.57382684
102RET0.57298213
103PDPK10.55453522
104CSNK1G20.55451687
105MAPK150.53893759
106STK160.53509654
107STK38L0.52666726
108MAPKAPK50.52247683
109ERBB20.51547710
110DYRK1A0.51400839
111SYK0.49613985
112MAPK70.49465714
113PRKCG0.49246966
114CSNK1A1L0.47586672
115PHKG10.45397523
116PHKG20.45397523
117CAMKK10.44557832
118STK390.44429182
119GRK10.43792098
120TEC0.43676395
121CAMK2G0.43462048
122IKBKE0.43300125
123SGK20.43195181
124PDK10.43192946
125MAP2K10.42537478
126CAMK2A0.41843588
127IGF1R0.41386666
128EPHA30.41074265
129CSNK2A10.40563292
130MAP3K60.39778748
131FGFR30.39675715
132TAOK20.39303662
133CDK40.38715758
134SGK2230.37857390
135SGK4940.37857390
136ICK0.37166213
137PRKCB0.36483112
138LYN0.36336760
139PDK20.36306919
140LATS20.36136257
141PRKACB0.34754523
142BRSK20.33528708
143CAMK40.31424037
144MTOR0.29976799
145MAP3K10.27368787
146KSR20.26433891
147PAK30.26431259
148MAP3K50.26229183
149PRKCA0.25504237
150PBK0.24311490
151BLK0.23314973
152RPS6KA30.21349367
153PDK40.21070941
154PDK30.21070941
155MAP2K20.20845448
156FGFR10.20503736
157PRKACA0.20096988

Predicted pathways (KEGG)

RankGene SetZ-score
1Primary bile acid biosynthesis_Homo sapiens_hsa001203.99772076
2Nitrogen metabolism_Homo sapiens_hsa009103.73956328
3Ascorbate and aldarate metabolism_Homo sapiens_hsa000533.72606769
4Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004003.21295720
5Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010403.01491340
6Arginine biosynthesis_Homo sapiens_hsa002202.99991597
7Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006302.66924156
8Tryptophan metabolism_Homo sapiens_hsa003802.55551982
9Glycine, serine and threonine metabolism_Homo sapiens_hsa002602.49637555
10Complement and coagulation cascades_Homo sapiens_hsa046102.46829784
11Fatty acid degradation_Homo sapiens_hsa000712.46549133
12Pentose and glucuronate interconversions_Homo sapiens_hsa000402.44056247
13Valine, leucine and isoleucine degradation_Homo sapiens_hsa002802.41445143
14Drug metabolism - cytochrome P450_Homo sapiens_hsa009822.37197291
15Butanoate metabolism_Homo sapiens_hsa006502.22795525
16Chemical carcinogenesis_Homo sapiens_hsa052042.17502447
17Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009802.14847976
18Propanoate metabolism_Homo sapiens_hsa006402.00610251
19Steroid hormone biosynthesis_Homo sapiens_hsa001401.99886131
20Histidine metabolism_Homo sapiens_hsa003401.98932619
21Peroxisome_Homo sapiens_hsa041461.96056266
22Drug metabolism - other enzymes_Homo sapiens_hsa009831.92133042
23Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.84100181
24Fatty acid metabolism_Homo sapiens_hsa012121.83892918
25PPAR signaling pathway_Homo sapiens_hsa033201.82805501
26Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002501.78153163
27beta-Alanine metabolism_Homo sapiens_hsa004101.77352086
28Staphylococcus aureus infection_Homo sapiens_hsa051501.76747277
29Retinol metabolism_Homo sapiens_hsa008301.75731312
30Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.61074402
31Selenocompound metabolism_Homo sapiens_hsa004501.60885211
32Phenylalanine metabolism_Homo sapiens_hsa003601.56255390
33Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.55423469
34Bile secretion_Homo sapiens_hsa049761.53964104
35Caffeine metabolism_Homo sapiens_hsa002321.48599385
36Sulfur metabolism_Homo sapiens_hsa009201.48200122
372-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.45817032
38Tyrosine metabolism_Homo sapiens_hsa003501.39749926
39Fatty acid elongation_Homo sapiens_hsa000621.35715719
40Pyruvate metabolism_Homo sapiens_hsa006201.33315244
41Steroid biosynthesis_Homo sapiens_hsa001001.28702221
42Cysteine and methionine metabolism_Homo sapiens_hsa002701.24258086
43Starch and sucrose metabolism_Homo sapiens_hsa005001.24008997
44Biosynthesis of amino acids_Homo sapiens_hsa012301.17049353
45ABC transporters_Homo sapiens_hsa020101.16861270
46Folate biosynthesis_Homo sapiens_hsa007901.15369233
47Cyanoamino acid metabolism_Homo sapiens_hsa004601.14171284
48Carbon metabolism_Homo sapiens_hsa012001.11531877
49Fat digestion and absorption_Homo sapiens_hsa049751.10879344
50Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008601.04458884
51Arginine and proline metabolism_Homo sapiens_hsa003301.03836120
52Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.92506707
53Sulfur relay system_Homo sapiens_hsa041220.88883386
54Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.87497936
55Maturity onset diabetes of the young_Homo sapiens_hsa049500.87325570
56Vitamin digestion and absorption_Homo sapiens_hsa049770.82571262
57Lysine degradation_Homo sapiens_hsa003100.80466537
58One carbon pool by folate_Homo sapiens_hsa006700.77144490
59Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.75605647
60Glycerolipid metabolism_Homo sapiens_hsa005610.70553061
61Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.68292837
62Glutathione metabolism_Homo sapiens_hsa004800.59086134
63Vitamin B6 metabolism_Homo sapiens_hsa007500.58164434
64Fatty acid biosynthesis_Homo sapiens_hsa000610.55429768
65Pentose phosphate pathway_Homo sapiens_hsa000300.54652076
66Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.44569407
67Metabolic pathways_Homo sapiens_hsa011000.44347389
68Systemic lupus erythematosus_Homo sapiens_hsa053220.39181138
69Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.33137226
70Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.29291141
71Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.28927902
72Phototransduction_Homo sapiens_hsa047440.27063231
73alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.25448794
74Linoleic acid metabolism_Homo sapiens_hsa005910.24314118
75Oxidative phosphorylation_Homo sapiens_hsa001900.24044286
76Serotonergic synapse_Homo sapiens_hsa047260.20688002
77Insulin resistance_Homo sapiens_hsa049310.20643410
78Galactose metabolism_Homo sapiens_hsa000520.20619902
79Adipocytokine signaling pathway_Homo sapiens_hsa049200.19582762
80Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.19151313
81Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.16950819
82Fructose and mannose metabolism_Homo sapiens_hsa000510.15147217
83Glycerophospholipid metabolism_Homo sapiens_hsa005640.12213377
84Mineral absorption_Homo sapiens_hsa049780.09879779
85Parkinsons disease_Homo sapiens_hsa050120.06289889
86Protein export_Homo sapiens_hsa030600.05788991
87Glucagon signaling pathway_Homo sapiens_hsa049220.05356657
88Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.00860602
89Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014-0.2552304
90Longevity regulating pathway - mammal_Homo sapiens_hsa04211-0.2496747
91Type II diabetes mellitus_Homo sapiens_hsa04930-0.2484876
92Regulation of autophagy_Homo sapiens_hsa04140-0.2447917
93Pertussis_Homo sapiens_hsa05133-0.2443373
94Hepatitis C_Homo sapiens_hsa05160-0.2386614
95Ether lipid metabolism_Homo sapiens_hsa00565-0.2330748
96Longevity regulating pathway - multiple species_Homo sapiens_hsa04213-0.2285940
97Carbohydrate digestion and absorption_Homo sapiens_hsa04973-0.2166738
98Arachidonic acid metabolism_Homo sapiens_hsa00590-0.1997861
99Glycosaminoglycan degradation_Homo sapiens_hsa00531-0.1954701
100Renin-angiotensin system_Homo sapiens_hsa04614-0.1905425
101Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520-0.1851091
102Thyroid hormone synthesis_Homo sapiens_hsa04918-0.1760365
103Central carbon metabolism in cancer_Homo sapiens_hsa05230-0.1652026
104Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604-0.1615114
105African trypanosomiasis_Homo sapiens_hsa05143-0.1383111
106Insulin signaling pathway_Homo sapiens_hsa04910-0.1198217
107Intestinal immune network for IgA production_Homo sapiens_hsa04672-0.1034101
108Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534-0.0835507
109Circadian rhythm_Homo sapiens_hsa04710-0.0653778
110Prion diseases_Homo sapiens_hsa05020-0.0518051
111Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932-0.0425466
112Ovarian steroidogenesis_Homo sapiens_hsa04913-0.0372147
113GABAergic synapse_Homo sapiens_hsa04727-0.0359161
114AMPK signaling pathway_Homo sapiens_hsa04152-0.0095041
115Nicotine addiction_Homo sapiens_hsa05033-0.0044350

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