AARSD1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1DNA strand elongation involved in DNA replication (GO:0006271)5.30975110
2establishment of protein localization to mitochondrial membrane (GO:0090151)5.23141194
3telomere maintenance via semi-conservative replication (GO:0032201)5.11460463
4DNA strand elongation (GO:0022616)5.08812619
5DNA deamination (GO:0045006)5.02926811
6DNA replication initiation (GO:0006270)4.91670423
7chaperone-mediated protein transport (GO:0072321)4.76351400
8nucleobase biosynthetic process (GO:0046112)4.70995054
9purine nucleobase biosynthetic process (GO:0009113)4.47572844
10DNA unwinding involved in DNA replication (GO:0006268)4.39691653
11telomere maintenance via recombination (GO:0000722)4.37711430
12mitochondrial electron transport, NADH to ubiquinone (GO:0006120)4.37360695
13DNA replication checkpoint (GO:0000076)4.17289424
14deoxyribonucleoside monophosphate metabolic process (GO:0009162)4.12750179
15cullin deneddylation (GO:0010388)4.10574726
16mitotic recombination (GO:0006312)4.09880706
17ribosomal small subunit assembly (GO:0000028)3.98850203
18protein deneddylation (GO:0000338)3.91761949
19negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)3.90624028
20telomere maintenance via telomere lengthening (GO:0010833)3.90074529
21respiratory electron transport chain (GO:0022904)3.88279760
22IMP biosynthetic process (GO:0006188)3.88024193
23formation of translation preinitiation complex (GO:0001731)3.85662099
24electron transport chain (GO:0022900)3.82603215
25respiratory chain complex IV assembly (GO:0008535)3.79536629
26proteasome assembly (GO:0043248)3.78893681
27ribosome biogenesis (GO:0042254)3.74448531
28mitochondrial ATP synthesis coupled proton transport (GO:0042776)3.70194950
29anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:03.69284094
30regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)3.67883082
31nucleotide-excision repair, DNA gap filling (GO:0006297)3.67446503
32pseudouridine synthesis (GO:0001522)3.66200563
33positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)3.64633469
34negative regulation of ligase activity (GO:0051352)3.58219636
35negative regulation of ubiquitin-protein transferase activity (GO:0051444)3.58219636
36maturation of SSU-rRNA (GO:0030490)3.58091044
37spliceosomal snRNP assembly (GO:0000387)3.56136147
38folic acid-containing compound biosynthetic process (GO:0009396)3.48685214
39L-methionine biosynthetic process from methylthioadenosine (GO:0019509)3.47903572
40establishment of integrated proviral latency (GO:0075713)3.47243107
41DNA replication-dependent nucleosome organization (GO:0034723)3.45610120
42DNA replication-dependent nucleosome assembly (GO:0006335)3.45610120
43protein targeting to mitochondrion (GO:0006626)3.45139843
44water-soluble vitamin biosynthetic process (GO:0042364)3.43425352
45cytochrome complex assembly (GO:0017004)3.43348498
46RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)3.42765397
47tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)3.42765397
48energy coupled proton transport, down electrochemical gradient (GO:0015985)3.42668714
49ATP synthesis coupled proton transport (GO:0015986)3.42668714
50behavioral response to nicotine (GO:0035095)3.41002814
51CENP-A containing nucleosome assembly (GO:0034080)3.40549863
52ribonucleoprotein complex biogenesis (GO:0022613)3.40398367
53peptidyl-histidine modification (GO:0018202)3.40054152
54regulation of cellular amino acid metabolic process (GO:0006521)3.39149604
55chromatin remodeling at centromere (GO:0031055)3.36276003
56protein localization to kinetochore (GO:0034501)3.36091617
57regulation of mitochondrial translation (GO:0070129)3.35124052
58establishment of protein localization to mitochondrion (GO:0072655)3.32777431
59DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:003.32544967
60IMP metabolic process (GO:0046040)3.31375002
61viral mRNA export from host cell nucleus (GO:0046784)3.30613492
62transcription-coupled nucleotide-excision repair (GO:0006283)3.30400359
63deoxyribonucleotide biosynthetic process (GO:0009263)3.30303962
64protein-cofactor linkage (GO:0018065)3.29304634
65signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)3.28535800
66intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)3.28535800
67rRNA processing (GO:0006364)3.28180199
68oxidative phosphorylation (GO:0006119)3.27462404
69mitochondrial respiratory chain complex I biogenesis (GO:0097031)3.27044790
70mitochondrial respiratory chain complex I assembly (GO:0032981)3.27044790
71NADH dehydrogenase complex assembly (GO:0010257)3.27044790
72protein localization to mitochondrion (GO:0070585)3.26617862
73signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)3.26202315
74signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)3.26202315
75signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)3.26202315
76G1/S transition of mitotic cell cycle (GO:0000082)3.24966172
77cell cycle G1/S phase transition (GO:0044843)3.24966172
78transcription elongation from RNA polymerase III promoter (GO:0006385)3.23457239
79termination of RNA polymerase III transcription (GO:0006386)3.23457239
80signal transduction involved in DNA integrity checkpoint (GO:0072401)3.20799846
81signal transduction involved in DNA damage checkpoint (GO:0072422)3.20799846
82protein neddylation (GO:0045116)3.20704813
83synapsis (GO:0007129)3.19915100
84mitotic metaphase plate congression (GO:0007080)3.19786315
85rRNA modification (GO:0000154)3.18081988
86histone H2A acetylation (GO:0043968)3.16576694
87signal transduction involved in cell cycle checkpoint (GO:0072395)3.16531940
88DNA replication-independent nucleosome organization (GO:0034724)3.16343920
89DNA replication-independent nucleosome assembly (GO:0006336)3.16343920
90rRNA metabolic process (GO:0016072)3.14442921
912-deoxyribonucleotide biosynthetic process (GO:0009265)3.12777432
92deoxyribose phosphate biosynthetic process (GO:0046385)3.12777432
93mitochondrial respiratory chain complex assembly (GO:0033108)3.12099801
94positive regulation of ubiquitin-protein transferase activity (GO:0051443)3.12065314
95cellular component biogenesis (GO:0044085)3.12016905
96spliceosomal complex assembly (GO:0000245)3.11786407
97nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)3.11738159
98viral transcription (GO:0019083)3.11713617
99exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 3.11024330
100guanosine-containing compound biosynthetic process (GO:1901070)3.10843684
101translational elongation (GO:0006414)3.09146411
102ribosomal small subunit biogenesis (GO:0042274)3.07703448
103ubiquinone biosynthetic process (GO:0006744)3.07700628
104translational termination (GO:0006415)3.07477119
105maturation of 5.8S rRNA (GO:0000460)3.06966980
106pyrimidine deoxyribonucleotide catabolic process (GO:0009223)3.06030221
107mitotic sister chromatid segregation (GO:0000070)3.05444385
108protein complex biogenesis (GO:0070271)3.04672004
109somatic diversification of immune receptors via somatic mutation (GO:0002566)3.04495252
110somatic hypermutation of immunoglobulin genes (GO:0016446)3.04495252
111* amino acid activation (GO:0043038)3.04225461
112* tRNA aminoacylation (GO:0043039)3.04225461
113* tRNA aminoacylation for protein translation (GO:0006418)3.04014625
114iron-sulfur cluster assembly (GO:0016226)3.03079566
115metallo-sulfur cluster assembly (GO:0031163)3.03079566
1167-methylguanosine mRNA capping (GO:0006370)3.00501952
117ribosome assembly (GO:0042255)3.00163496
118positive regulation of ligase activity (GO:0051351)2.99138089
119DNA damage response, detection of DNA damage (GO:0042769)2.98143149
1207-methylguanosine RNA capping (GO:0009452)2.97712623
121DNA double-strand break processing (GO:0000729)2.96760232
122ribosomal large subunit biogenesis (GO:0042273)2.93675677
123positive regulation of mitochondrial fission (GO:0090141)2.92842619
124intracellular protein transmembrane import (GO:0044743)2.91794546
125ubiquinone metabolic process (GO:0006743)2.91752558
126inner mitochondrial membrane organization (GO:0007007)2.91684311
127replication fork processing (GO:0031297)2.89399321
128tRNA processing (GO:0008033)2.88581607
129rRNA methylation (GO:0031167)2.85921295
130preassembly of GPI anchor in ER membrane (GO:0016254)2.81362000
131resolution of meiotic recombination intermediates (GO:0000712)2.80592196
132purine nucleoside triphosphate biosynthetic process (GO:0009145)2.79571002
133ATP biosynthetic process (GO:0006754)2.79274052
134purine ribonucleoside triphosphate biosynthetic process (GO:0009206)2.78139747
135* tRNA metabolic process (GO:0006399)2.75271830
136GTP biosynthetic process (GO:0006183)2.74547781
137protein polyglutamylation (GO:0018095)2.73323508
138translation (GO:0006412)2.71188360
139base-excision repair, AP site formation (GO:0006285)2.67621761
140histone exchange (GO:0043486)2.66534601
141DNA catabolic process, exonucleolytic (GO:0000738)2.65199410
142hydrogen ion transmembrane transport (GO:1902600)2.64997347
143ribonucleoside triphosphate biosynthetic process (GO:0009201)2.63867927
144regulation of mitotic spindle checkpoint (GO:1903504)2.63343328
145regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)2.63343328

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human7.83161746
2MYC_18555785_ChIP-Seq_MESCs_Mouse4.43282265
3* EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse4.41311104
4KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human4.01321543
5* JARID1A_20064375_ChIP-Seq_MESCs_Mouse3.64470235
6EST1_17652178_ChIP-ChIP_JURKAT_Human3.58484226
7HCFC1_20581084_ChIP-Seq_MESCs_Mouse3.42745647
8NOTCH1_17114293_ChIP-ChIP_T-ALL_Human3.42025732
9E2F4_17652178_ChIP-ChIP_JURKAT_Human3.38618196
10ETS1_20019798_ChIP-Seq_JURKAT_Human3.34954423
11GABP_17652178_ChIP-ChIP_JURKAT_Human3.29710305
12MYC_18358816_ChIP-ChIP_MESCs_Mouse3.22081324
13* MYC_19030024_ChIP-ChIP_MESCs_Mouse2.92185628
14MYC_19079543_ChIP-ChIP_MESCs_Mouse2.91112465
15CREB1_15753290_ChIP-ChIP_HEK293T_Human2.87853933
16THAP11_20581084_ChIP-Seq_MESCs_Mouse2.71275880
17FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.58466584
18ZNF274_21170338_ChIP-Seq_K562_Hela2.51448752
19FOXM1_23109430_ChIP-Seq_U2OS_Human2.50892674
20HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.50308299
21XRN2_22483619_ChIP-Seq_HELA_Human2.46825746
22CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.44596791
23VDR_23849224_ChIP-Seq_CD4+_Human2.42831950
24ELF1_17652178_ChIP-ChIP_JURKAT_Human2.36574174
25NELFA_20434984_ChIP-Seq_ESCs_Mouse2.28325321
26* E2F1_18555785_ChIP-Seq_MESCs_Mouse2.25370326
27YY1_21170310_ChIP-Seq_MESCs_Mouse2.22485991
28FOXP3_21729870_ChIP-Seq_TREG_Human2.21519336
29DCP1A_22483619_ChIP-Seq_HELA_Human2.17571620
30* GABP_19822575_ChIP-Seq_HepG2_Human2.13346378
31E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.13228066
32SOX9_22984422_ChIP-ChIP_TESTIS_Rat2.10765937
33PDX1_19855005_ChIP-ChIP_MIN6_Mouse2.10109607
34SRF_21415370_ChIP-Seq_HL-1_Mouse2.01880023
35ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.95436446
36* TTF2_22483619_ChIP-Seq_HELA_Human1.93591575
37MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.89507011
38MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.87307632
39POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.83548935
40YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.82393547
41CIITA_25753668_ChIP-Seq_RAJI_Human1.81740244
42PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.79961860
43MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.79422769
44MYCN_18555785_ChIP-Seq_MESCs_Mouse1.78644318
45CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.78225999
46VDR_22108803_ChIP-Seq_LS180_Human1.70732356
47E2F1_21310950_ChIP-Seq_MCF-7_Human1.68734745
48* FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.67796442
49NANOG_18555785_ChIP-Seq_MESCs_Mouse1.67488656
50IGF1R_20145208_ChIP-Seq_DFB_Human1.62694860
51* ZFX_18555785_ChIP-Seq_MESCs_Mouse1.61852203
52SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.61789550
53NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.60536637
54HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.58961328
55TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.52431396
56RBPJ_22232070_ChIP-Seq_NCS_Mouse1.51041034
57AR_21909140_ChIP-Seq_LNCAP_Human1.50184123
58ELK1_19687146_ChIP-ChIP_HELA_Human1.49644825
59HOXB4_20404135_ChIP-ChIP_EML_Mouse1.47894723
60CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.43685222
61FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.38436908
62* KDM5A_27292631_Chip-Seq_BREAST_Human1.35038993
63ERG_20887958_ChIP-Seq_HPC-7_Mouse1.31341224
64POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.30970735
65SIN3A_21632747_ChIP-Seq_MESCs_Mouse1.29822571
66EZH2_22144423_ChIP-Seq_EOC_Human1.29624974
67EWS_26573619_Chip-Seq_HEK293_Human1.29485996
68PADI4_21655091_ChIP-ChIP_MCF-7_Human1.27971248
69FUS_26573619_Chip-Seq_HEK293_Human1.24058632
70FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.21858798
71SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.20936675
72DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.15881735
73E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.13588771
74MYC_18940864_ChIP-ChIP_HL60_Human1.12496128
75BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.12492026
76POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.12144354
77KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.12109066
78TP53_22573176_ChIP-Seq_HFKS_Human1.10097390
79* IRF1_19129219_ChIP-ChIP_H3396_Human1.09711813
80EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.08263063
81SOX2_16153702_ChIP-ChIP_HESCs_Human1.07740341
82SOX2_18555785_ChIP-Seq_MESCs_Mouse1.06189625
83CTBP1_25329375_ChIP-Seq_LNCAP_Human1.03389029
84POU5F1_16153702_ChIP-ChIP_HESCs_Human1.02012472
85FLI1_27457419_Chip-Seq_LIVER_Mouse1.00841195
86MYC_22102868_ChIP-Seq_BL_Human1.00347862
87CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.98654538
88CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat0.98213105
89CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.97854279
90TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat0.97000417
91MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human0.96896534
92CEBPA_23403033_ChIP-Seq_LIVER_Mouse0.96862534
93STAT3_1855785_ChIP-Seq_MESCs_Mouse0.96797010
94KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.95665762
95GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.94937469
96NANOG_16153702_ChIP-ChIP_HESCs_Human0.92847012
97* CEBPB_24764292_ChIP-Seq_MC3T3_Mouse0.92625697
98ESRRB_18555785_ChIP-Seq_MESCs_Mouse0.91957602
99CTCF_18555785_ChIP-Seq_MESCs_Mouse0.91607356
100CTBP2_25329375_ChIP-Seq_LNCAP_Human0.91602688
101TFEB_21752829_ChIP-Seq_HELA_Human0.90800491
102DACH1_20351289_ChIP-Seq_MDA-MB-231_Human0.90525341
103* ASH2L_23239880_ChIP-Seq_MESCs_Mouse0.90398987
104CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons0.89897493
105PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse0.89776696
106NOTCH1_21737748_ChIP-Seq_TLL_Human0.88634249
107CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.86901879
108CEBPB_23403033_ChIP-Seq_LIVER_Mouse0.85924242
109FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse0.85521522
110SMAD1_18555785_ChIP-Seq_MESCs_Mouse0.84096886
111CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse0.83876378
112KLF4_18555785_ChIP-Seq_MESCs_Mouse0.83768261
113* ELK1_22589737_ChIP-Seq_MCF10A_Human0.82750342
114NCOR_22424771_ChIP-Seq_293T_Human0.80859396
115BMI1_23680149_ChIP-Seq_NPCS_Mouse0.79726667
116YY1_22570637_ChIP-Seq_MALME-3M_Human0.79273732
117GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.78987285
118SIN3B_21632747_ChIP-Seq_MESCs_Mouse0.78757349
119GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse0.78465867
120FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.78132223
121CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human0.77649952
122EBNA2_21746931_ChIP-Seq_IB4-LCL_Human0.77542738
123ZFP57_27257070_Chip-Seq_ESCs_Mouse0.77231590
124* FOXP1_21924763_ChIP-Seq_HESCs_Human0.75307305
125OCT4_18692474_ChIP-Seq_MEFs_Mouse0.74316216
126CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse0.73057055
127ASXL1_24218140_ChIP-Seq_BMDM_Mouse0.73011446
128FOXA1_27270436_Chip-Seq_PROSTATE_Human0.72808593
129FOXA1_25329375_ChIP-Seq_VCAP_Human0.72808593
130* TBX5_21415370_ChIP-Seq_HL-1_Mouse0.70825090

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching4.73328528
2MP0010094_abnormal_chromosome_stability4.63574075
3MP0004957_abnormal_blastocyst_morpholog4.26921095
4MP0003111_abnormal_nucleus_morphology4.09699889
5MP0008057_abnormal_DNA_replication3.70535249
6MP0003077_abnormal_cell_cycle3.58960032
7MP0008058_abnormal_DNA_repair3.40670011
8MP0008932_abnormal_embryonic_tissue2.69074099
9MP0001529_abnormal_vocalization2.67051906
10MP0008877_abnormal_DNA_methylation2.64819612
11MP0003123_paternal_imprinting2.55923732
12MP0002837_dystrophic_cardiac_calcinosis2.44910291
13MP0006036_abnormal_mitochondrial_physio2.40955001
14MP0008007_abnormal_cellular_replicative2.38048683
15MP0006035_abnormal_mitochondrial_morpho2.26897973
16MP0003806_abnormal_nucleotide_metabolis2.25144662
17MP0002102_abnormal_ear_morphology2.14092682
18MP0004147_increased_porphyrin_level2.08583147
19MP0002822_catalepsy1.94871610
20MP0006292_abnormal_olfactory_placode1.89662824
21MP0001730_embryonic_growth_arrest1.88631283
22MP0009379_abnormal_foot_pigmentation1.87354986
23MP0003646_muscle_fatigue1.85722744
24MP0002396_abnormal_hematopoietic_system1.79268763
25MP0003786_premature_aging1.78816538
26MP0000372_irregular_coat_pigmentation1.71759670
27MP0004145_abnormal_muscle_electrophysio1.70831085
28MP0003880_abnormal_central_pattern1.65691570
29MP0000350_abnormal_cell_proliferation1.56928333
30MP0003718_maternal_effect1.51096230
31MP0003186_abnormal_redox_activity1.50782469
32MP0008995_early_reproductive_senescence1.50395391
33MP0002653_abnormal_ependyma_morphology1.50001800
34MP0001485_abnormal_pinna_reflex1.44395624
35MP0003121_genomic_imprinting1.42918813
36MP0005551_abnormal_eye_electrophysiolog1.42657239
37MP0003656_abnormal_erythrocyte_physiolo1.42591937
38MP0005084_abnormal_gallbladder_morpholo1.42210470
39MP0001905_abnormal_dopamine_level1.41077330
40MP0000358_abnormal_cell_content/1.39517463
41MP0000049_abnormal_middle_ear1.35675971
42MP0002736_abnormal_nociception_after1.34724197
43MP0002938_white_spotting1.32351082
44MP0001968_abnormal_touch/_nociception1.27662285
45MP0005075_abnormal_melanosome_morpholog1.27416656
46MP0002080_prenatal_lethality1.27252801
47MP0002638_abnormal_pupillary_reflex1.26635937
48MP0004142_abnormal_muscle_tone1.25301298
49MP0005253_abnormal_eye_physiology1.25147724
50MP0003011_delayed_dark_adaptation1.23166305
51MP0000313_abnormal_cell_death1.22678239
52MP0001697_abnormal_embryo_size1.19136859
53MP0001764_abnormal_homeostasis1.18147955
54MP0006276_abnormal_autonomic_nervous1.17784965
55MP0000631_abnormal_neuroendocrine_gland1.14504287
56MP0005266_abnormal_metabolism1.14350749
57MP0009697_abnormal_copulation1.12435893
58MP0001293_anophthalmia1.11660919
59MP0008872_abnormal_physiological_respon1.08435231
60MP0002132_abnormal_respiratory_system1.07444939
61MP0009745_abnormal_behavioral_response1.06177587
62MP0000490_abnormal_crypts_of1.05372531
63MP0003635_abnormal_synaptic_transmissio1.04708119
64MP0002160_abnormal_reproductive_system1.03903385
65MP0004133_heterotaxia1.03848360
66MP0004859_abnormal_synaptic_plasticity1.03827731
67MP0005394_taste/olfaction_phenotype1.03244045
68MP0005499_abnormal_olfactory_system1.03244045
69MP0003787_abnormal_imprinting1.01081996
70MP0002064_seizures1.01042614
71MP0001188_hyperpigmentation1.01014041
72MP0002019_abnormal_tumor_incidence1.00627526
73MP0001984_abnormal_olfaction1.00234164
74MP0002272_abnormal_nervous_system0.99518875
75MP0003890_abnormal_embryonic-extraembry0.96551508
76MP0003698_abnormal_male_reproductive0.96322820
77MP0002735_abnormal_chemical_nociception0.95127673
78MP0003567_abnormal_fetal_cardiomyocyte0.94893566
79MP0006054_spinal_hemorrhage0.94290637
80MP0005367_renal/urinary_system_phenotyp0.93833121
81MP0000516_abnormal_urinary_system0.93833121
82MP0005646_abnormal_pituitary_gland0.93539464
83MP0008789_abnormal_olfactory_epithelium0.91940765
84MP0001672_abnormal_embryogenesis/_devel0.91579647
85MP0005380_embryogenesis_phenotype0.91579647
86MP0005645_abnormal_hypothalamus_physiol0.90385760
87MP0003119_abnormal_digestive_system0.88785956
88MP0002557_abnormal_social/conspecific_i0.88140672
89MP0005423_abnormal_somatic_nervous0.87642378
90MP0005397_hematopoietic_system_phenotyp0.87408584
91MP0001545_abnormal_hematopoietic_system0.87408584
92MP0003136_yellow_coat_color0.86414125
93MP0002063_abnormal_learning/memory/cond0.85692031
94MP0000778_abnormal_nervous_system0.85205416
95MP0002085_abnormal_embryonic_tissue0.84789493
96MP0002752_abnormal_somatic_nervous0.83512816
97MP0003122_maternal_imprinting0.83351758
98MP0003937_abnormal_limbs/digits/tail_de0.83265677
99MP0008260_abnormal_autophagy0.82720645
100MP0002210_abnormal_sex_determination0.82411632
101MP0004811_abnormal_neuron_physiology0.82231625
102MP0002734_abnormal_mechanical_nocicepti0.82200672
103MP0005410_abnormal_fertilization0.81419066
104MP0002067_abnormal_sensory_capabilities0.80907046
105MP0002184_abnormal_innervation0.80898243
106MP0000015_abnormal_ear_pigmentation0.80522560
107MP0002572_abnormal_emotion/affect_behav0.80426137
108MP0005195_abnormal_posterior_eye0.80316445
109MP0005409_darkened_coat_color0.80028762
110MP0003221_abnormal_cardiomyocyte_apopto0.79888638
111MP0001145_abnormal_male_reproductive0.79441582
112MP0004215_abnormal_myocardial_fiber0.79193621
113MP0006072_abnormal_retinal_apoptosis0.78416063
114MP0001486_abnormal_startle_reflex0.78351405
115MP0002751_abnormal_autonomic_nervous0.77251768
116MP0000749_muscle_degeneration0.76905009
117MP0003984_embryonic_growth_retardation0.76439657
118MP0009046_muscle_twitch0.76368292
119MP0005174_abnormal_tail_pigmentation0.72045875
120MP0003315_abnormal_perineum_morphology0.71835695
121MP0002088_abnormal_embryonic_growth/wei0.70983135
122MP0005389_reproductive_system_phenotype0.70299602
123MP0002095_abnormal_skin_pigmentation0.69792794
124MP0001929_abnormal_gametogenesis0.69029489
125MP0005384_cellular_phenotype0.68884759
126MP0005386_behavior/neurological_phenoty0.67978234
127MP0004924_abnormal_behavior0.67978234
128MP0001970_abnormal_pain_threshold0.67784670
129MP0002876_abnormal_thyroid_physiology0.67099941
130MP0001986_abnormal_taste_sensitivity0.66896282
131MP0002084_abnormal_developmental_patter0.66561266
132MP0000653_abnormal_sex_gland0.64621845
133MP0002163_abnormal_gland_morphology0.64308990
134MP0005376_homeostasis/metabolism_phenot0.62263293

Predicted human phenotypes

RankGene SetZ-score
1Birth length less than 3rd percentile (HP:0003561)4.35362246
2Acute necrotizing encephalopathy (HP:0006965)4.32147711
3Abnormality of cells of the erythroid lineage (HP:0012130)4.24336293
4Abnormal number of erythroid precursors (HP:0012131)4.19539412
5Abnormal mitochondria in muscle tissue (HP:0008316)4.18550044
6Hepatocellular necrosis (HP:0001404)4.01054241
7Mitochondrial inheritance (HP:0001427)3.86926306
8Increased CSF lactate (HP:0002490)3.86823083
9Abnormality of the heme biosynthetic pathway (HP:0010472)3.74957213
10Cerebral hypomyelination (HP:0006808)3.71783988
11Acute encephalopathy (HP:0006846)3.59974035
12Hepatic necrosis (HP:0002605)3.57055012
13Increased serum lactate (HP:0002151)3.56843748
14Abnormality of glycolysis (HP:0004366)3.49282179
15Increased serum pyruvate (HP:0003542)3.49282179
16Decreased activity of mitochondrial respiratory chain (HP:0008972)3.40774192
17Abnormal activity of mitochondrial respiratory chain (HP:0011922)3.40774192
18Progressive macrocephaly (HP:0004481)3.32504277
19Agnosia (HP:0010524)3.22078898
20Oral leukoplakia (HP:0002745)3.17140395
21Aplastic anemia (HP:0001915)3.02524961
22Breast hypoplasia (HP:0003187)2.94596145
23Methylmalonic acidemia (HP:0002912)2.91921180
24Lactic acidosis (HP:0003128)2.90535895
25Reticulocytopenia (HP:0001896)2.88559710
26Microvesicular hepatic steatosis (HP:0001414)2.83664531
27Pancreatic fibrosis (HP:0100732)2.82421658
283-Methylglutaconic aciduria (HP:0003535)2.79240998
29Ependymoma (HP:0002888)2.74870096
30Methylmalonic aciduria (HP:0012120)2.74203187
31Pancreatic cysts (HP:0001737)2.72099503
32Abnormality of midbrain morphology (HP:0002418)2.68973111
33Molar tooth sign on MRI (HP:0002419)2.68973111
34Emotional lability (HP:0000712)2.67552750
35Rough bone trabeculation (HP:0100670)2.54777416
36Unsteady gait (HP:0002317)2.54551717
37Nephronophthisis (HP:0000090)2.51609134
38Exercise intolerance (HP:0003546)2.51235824
39Macrocytic anemia (HP:0001972)2.47390060
40Abnormality of the labia minora (HP:0012880)2.47166595
41Type I transferrin isoform profile (HP:0003642)2.46886714
42Pendular nystagmus (HP:0012043)2.46805802
43True hermaphroditism (HP:0010459)2.44569914
44CNS hypomyelination (HP:0003429)2.44050137
45Degeneration of anterior horn cells (HP:0002398)2.42493818
46Abnormality of the anterior horn cell (HP:0006802)2.42493818
47Microretrognathia (HP:0000308)2.41823043
48Medulloblastoma (HP:0002885)2.41312916
49Respiratory failure (HP:0002878)2.40956377
50CNS demyelination (HP:0007305)2.38752953
51Cerebral edema (HP:0002181)2.37268877
52Hypoplasia of the pons (HP:0012110)2.36441741
53Increased muscle lipid content (HP:0009058)2.34992371
54Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.34630191
55Carpal bone hypoplasia (HP:0001498)2.32927185
56Renal Fanconi syndrome (HP:0001994)2.32844821
57Chromosomal breakage induced by crosslinking agents (HP:0003221)2.32450491
58Stenosis of the external auditory canal (HP:0000402)2.30990058
59Delusions (HP:0000746)2.28271941
60Increased hepatocellular lipid droplets (HP:0006565)2.26938135
61Colon cancer (HP:0003003)2.26243837
62Hyperglycinemia (HP:0002154)2.25223044
63Leukodystrophy (HP:0002415)2.22676725
64Horseshoe kidney (HP:0000085)2.19841501
65Muscle abnormality related to mitochondrial dysfunction (HP:0003800)2.19318204
66Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.18811481
67Abnormality of alanine metabolism (HP:0010916)2.18811481
68Hyperalaninemia (HP:0003348)2.18811481
69Abnormality of the preputium (HP:0100587)2.18686054
70Type 2 muscle fiber atrophy (HP:0003554)2.18517208
71Abnormality of the pons (HP:0007361)2.17807266
72Premature graying of hair (HP:0002216)2.17337472
73Megaloblastic anemia (HP:0001889)2.13981618
74Hypoplasia of the capital femoral epiphysis (HP:0003090)2.13423991
75Abnormality of the ileum (HP:0001549)2.11636757
76Bone marrow hypocellularity (HP:0005528)2.10505255
77Abnormality of the renal collecting system (HP:0004742)2.10345214
78Lipid accumulation in hepatocytes (HP:0006561)2.09813459
79Selective tooth agenesis (HP:0001592)2.09642094
80Congenital stationary night blindness (HP:0007642)2.08264671
81Pallor (HP:0000980)2.07560889
82Severe visual impairment (HP:0001141)2.07529144
83Postnatal microcephaly (HP:0005484)2.06747791
84Medial flaring of the eyebrow (HP:0010747)2.06743906
85Atrophy/Degeneration involving motor neurons (HP:0007373)2.03814824
86Abnormality of chromosome stability (HP:0003220)2.03437809
87Patellar aplasia (HP:0006443)2.02422576
88Optic disc pallor (HP:0000543)2.02348815
89Lethargy (HP:0001254)2.01990730
90Meckel diverticulum (HP:0002245)2.00288542
91Gliosis (HP:0002171)1.98449119
92Ectopic kidney (HP:0000086)1.98279151
93Duplicated collecting system (HP:0000081)1.97438283
94Abnormality of DNA repair (HP:0003254)1.97072357
95Pancytopenia (HP:0001876)1.96873983
96Abnormal number of incisors (HP:0011064)1.95019157
97Retinal dysplasia (HP:0007973)1.94916530
98Muscle fiber atrophy (HP:0100295)1.93745283
99Type II lissencephaly (HP:0007260)1.93089891
100Sclerocornea (HP:0000647)1.92444842
101Aplasia/Hypoplasia of the uvula (HP:0010293)1.91267113
102Small intestinal stenosis (HP:0012848)1.91110738
103Duodenal stenosis (HP:0100867)1.91110738
104Increased intramyocellular lipid droplets (HP:0012240)1.90821152
105Myelodysplasia (HP:0002863)1.89798100
106Tongue fasciculations (HP:0001308)1.88792588
107Cellular immunodeficiency (HP:0005374)1.87457166
108Aplasia/Hypoplasia of the sacrum (HP:0008517)1.87323619
109Abnormal lung lobation (HP:0002101)1.86599648
110Poor suck (HP:0002033)1.85935120
111Rhabdomyosarcoma (HP:0002859)1.85677193
112Testicular atrophy (HP:0000029)1.85014534
113Aplasia/Hypoplasia of the patella (HP:0006498)1.84458957
114Abnormality of the renal medulla (HP:0100957)1.84425319
115Ragged-red muscle fibers (HP:0003200)1.83756884
116Chromsome breakage (HP:0040012)1.83325801
117Optic nerve coloboma (HP:0000588)1.83249212
118Absent thumb (HP:0009777)1.81966852
119Neuroblastoma (HP:0003006)1.81798348
120Primitive neuroectodermal tumor (HP:0030065)1.81798348
121Neuroblastic tumors (HP:0004376)1.81798348
122Peripheral primitive neuroectodermal neoplasm (HP:0030067)1.81798348
123Multiple enchondromatosis (HP:0005701)1.81237831
124Abolished electroretinogram (ERG) (HP:0000550)1.80560591
12511 pairs of ribs (HP:0000878)1.78909823
126Gait imbalance (HP:0002141)1.78220902
127Abnormality of glycine metabolism (HP:0010895)1.78072714
128Abnormality of serine family amino acid metabolism (HP:0010894)1.78072714
129Abnormal protein glycosylation (HP:0012346)1.77016155
130Abnormal glycosylation (HP:0012345)1.77016155
131Abnormal isoelectric focusing of serum transferrin (HP:0003160)1.77016155
132Abnormal protein N-linked glycosylation (HP:0012347)1.77016155
133Aplasia/hypoplasia of the uterus (HP:0008684)1.75426288
134Abnormality of serum amino acid levels (HP:0003112)1.74404831
135Hyperglycinuria (HP:0003108)1.73234581
136Myokymia (HP:0002411)1.71547724
137Congenital primary aphakia (HP:0007707)1.70875537
138Sloping forehead (HP:0000340)1.70799918
139Impulsivity (HP:0100710)1.70786363
140Dicarboxylic aciduria (HP:0003215)1.69659596
141Abnormality of dicarboxylic acid metabolism (HP:0010995)1.69659596
142Limb dystonia (HP:0002451)1.68283314
143Exertional dyspnea (HP:0002875)1.67485380

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BUB15.02174368
2WEE13.83351714
3VRK23.53563060
4STK163.53374447
5TSSK63.43468320
6CDC73.31011189
7EIF2AK13.11123331
8CCNB12.98844227
9NEK12.83289174
10WNK32.57264901
11EIF2AK32.39842816
12VRK12.30290990
13SRPK12.13450743
14MAP4K22.12143221
15NME22.05065001
16ACVR1B2.01929649
17GRK11.99978262
18MAP3K121.98998645
19DAPK11.96553115
20BRSK11.94594708
21TRIM281.90177368
22NUAK11.85755032
23BMPR1B1.73774114
24PASK1.70416027
25SCYL21.62903267
26WNK41.62558399
27PLK31.61098463
28BRSK21.60138939
29PLK11.56715829
30NME11.53248338
31CASK1.50246505
32CDK191.48273889
33PDK21.43727440
34NEK21.42722950
35BCKDK1.40327190
36AURKA1.37016114
37TESK21.36535273
38ATR1.36320534
39BRAF1.35640627
40TTK1.35522390
41CSNK1G21.32140812
42FRK1.28900185
43MKNK11.24763150
44CSNK1G11.23032074
45PHKG11.19271853
46PHKG21.19271853
47PLK41.18604612
48PBK1.17632022
49DYRK31.16509506
50CSNK1A1L1.08465409
51AURKB1.08189616
52CDK71.03170541
53TAF11.03153444
54CHEK21.01253720
55TNIK1.00496062
56ARAF0.96434253
57SIK30.90271476
58STK390.88489350
59OXSR10.87874364
60UHMK10.86361570
61AKT30.85873441
62TLK10.84603039
63PDK40.84479675
64PDK30.84479675
65CHEK10.81564550
66MAP2K70.81280573
67OBSCN0.81114063
68CDK80.80358363
69RPS6KA50.79699247
70MKNK20.78920770
71GRK60.78680925
72RPS6KB20.76112702
73MINK10.73005206
74CSNK2A20.69776042
75PIM20.69503135
76CSNK2A10.68509067
77LIMK10.66607981
78CDK180.64626973
79EIF2AK20.64121216
80NTRK30.63140642
81MAPKAPK30.62690201
82KDR0.62515337
83CDK40.61747014
84DYRK20.61680214
85DAPK20.59768582
86CDK150.59635429
87PLK20.59464020
88CDK11A0.58173867
89RPS6KA40.57692414
90CSNK1A10.57186432
91INSRR0.56688044
92ZAK0.56680839
93CDK20.55780529
94PAK40.55497751
95MAP3K80.53954700
96BCR0.53673442
97MAPK130.52982036
98ALK0.52700581
99CDK140.52609545
100PRKCI0.52544262
101ATM0.47426541
102PAK10.47420696
103ERBB30.47298810
104PRKCE0.46110111
105EPHA40.46081152
106PINK10.46069479
107PRKCG0.46000130
108TGFBR10.45392967
109CDK10.44990019
110MAP2K30.44713912
111STK38L0.43730175
112PNCK0.43220664
113MUSK0.42367709
114PAK30.42213589
115FLT30.41327854
116CAMK2A0.40694233
117MAPKAPK50.39531758
118AKT20.39068638
119ADRBK20.36262434
120ADRBK10.35827453
121DAPK30.34417371
122MAP3K110.34132316
123MST40.33831275
124MAP2K60.33107924
125MARK10.31203159
126RPS6KL10.31185631
127RPS6KC10.31185631
128GRK50.30347022
129RPS6KB10.30167626
130YES10.28606575
131ABL20.28322640
132RAF10.28091666
133MAP3K40.27744743
134CSNK1G30.27228850
135CSNK1E0.26832671
136TAOK20.26411867
137SYK0.25457360
138MYLK0.24428556

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030305.21556552
2Mismatch repair_Homo sapiens_hsa034304.32751458
3Proteasome_Homo sapiens_hsa030504.20867884
4Ribosome_Homo sapiens_hsa030103.33190032
5Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030083.11126737
6RNA polymerase_Homo sapiens_hsa030203.08085891
7Spliceosome_Homo sapiens_hsa030402.94608533
8Homologous recombination_Homo sapiens_hsa034402.89096322
9Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009702.74319782
10Base excision repair_Homo sapiens_hsa034102.71048493
11Nucleotide excision repair_Homo sapiens_hsa034202.70287619
12Pyrimidine metabolism_Homo sapiens_hsa002402.57964462
13RNA transport_Homo sapiens_hsa030132.39447986
14Oxidative phosphorylation_Homo sapiens_hsa001902.38507451
15Parkinsons disease_Homo sapiens_hsa050122.33044930
16One carbon pool by folate_Homo sapiens_hsa006702.25068578
17Citrate cycle (TCA cycle)_Homo sapiens_hsa000202.08542564
18Cell cycle_Homo sapiens_hsa041101.92040222
19Fanconi anemia pathway_Homo sapiens_hsa034601.82872862
20Huntingtons disease_Homo sapiens_hsa050161.75651953
21Protein export_Homo sapiens_hsa030601.66193824
22RNA degradation_Homo sapiens_hsa030181.63546240
232-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.63497654
24Purine metabolism_Homo sapiens_hsa002301.53842882
25Non-homologous end-joining_Homo sapiens_hsa034501.53237011
26Cysteine and methionine metabolism_Homo sapiens_hsa002701.47930452
27Biosynthesis of amino acids_Homo sapiens_hsa012301.38580385
28Alzheimers disease_Homo sapiens_hsa050101.36011499
29Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.35360823
30Basal transcription factors_Homo sapiens_hsa030221.31336410
31Butanoate metabolism_Homo sapiens_hsa006501.28163514
32Cyanoamino acid metabolism_Homo sapiens_hsa004601.17755267
33mRNA surveillance pathway_Homo sapiens_hsa030151.13398130
34Folate biosynthesis_Homo sapiens_hsa007901.10573865
35Carbon metabolism_Homo sapiens_hsa012001.08593468
36Sulfur relay system_Homo sapiens_hsa041221.08492743
37Steroid biosynthesis_Homo sapiens_hsa001000.97137468
38Synaptic vesicle cycle_Homo sapiens_hsa047210.96877445
39Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.96874702
40Pentose phosphate pathway_Homo sapiens_hsa000300.96637968
41Pyruvate metabolism_Homo sapiens_hsa006200.94595103
42Oocyte meiosis_Homo sapiens_hsa041140.93500326
43Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.93293700
44Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.91122892
45Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.90797035
46Vitamin B6 metabolism_Homo sapiens_hsa007500.89833011
47Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.83851367
48Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.83744782
49Collecting duct acid secretion_Homo sapiens_hsa049660.81961441
50Nitrogen metabolism_Homo sapiens_hsa009100.81682086
51Drug metabolism - other enzymes_Homo sapiens_hsa009830.79811641
52Epstein-Barr virus infection_Homo sapiens_hsa051690.77596600
53Systemic lupus erythematosus_Homo sapiens_hsa053220.73181067
54Tryptophan metabolism_Homo sapiens_hsa003800.72211105
55beta-Alanine metabolism_Homo sapiens_hsa004100.71258636
56Fructose and mannose metabolism_Homo sapiens_hsa000510.68246313
57Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.67710459
58Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.67036940
59p53 signaling pathway_Homo sapiens_hsa041150.66358186
60N-Glycan biosynthesis_Homo sapiens_hsa005100.63896209
61Sulfur metabolism_Homo sapiens_hsa009200.63804064
62Metabolic pathways_Homo sapiens_hsa011000.60792784
63Cardiac muscle contraction_Homo sapiens_hsa042600.60439880
64Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.60426165
65Nicotine addiction_Homo sapiens_hsa050330.58749772
66Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.58267822
67Alcoholism_Homo sapiens_hsa050340.56999612
68Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.56461015
69Vibrio cholerae infection_Homo sapiens_hsa051100.55854224
70Glutathione metabolism_Homo sapiens_hsa004800.55134443
71Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.54962498
72Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.53585589
73Fatty acid metabolism_Homo sapiens_hsa012120.52719125
74Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.52481930
75Galactose metabolism_Homo sapiens_hsa000520.47859726
76Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.47817823
77Fatty acid degradation_Homo sapiens_hsa000710.47658826
78Maturity onset diabetes of the young_Homo sapiens_hsa049500.45742442
79Linoleic acid metabolism_Homo sapiens_hsa005910.43605695
80Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.41173365
81Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.40350412
82Chemical carcinogenesis_Homo sapiens_hsa052040.38029755
83Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.36565426
84Caffeine metabolism_Homo sapiens_hsa002320.34889757
85Arginine and proline metabolism_Homo sapiens_hsa003300.34311354
86Primary immunodeficiency_Homo sapiens_hsa053400.34251286
87Primary bile acid biosynthesis_Homo sapiens_hsa001200.32420590
88Selenocompound metabolism_Homo sapiens_hsa004500.30887913
89Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.29478621
90Regulation of autophagy_Homo sapiens_hsa041400.27540694
91Morphine addiction_Homo sapiens_hsa050320.27148449
92SNARE interactions in vesicular transport_Homo sapiens_hsa041300.26911912
93Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.26308643
94alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.25829090
95Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.25813219
96Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.25534009
97Retinol metabolism_Homo sapiens_hsa008300.24986987
98Pentose and glucuronate interconversions_Homo sapiens_hsa000400.23838374
99Tyrosine metabolism_Homo sapiens_hsa003500.23323191
100Antigen processing and presentation_Homo sapiens_hsa046120.23057194
101Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.21848687
102Phenylalanine metabolism_Homo sapiens_hsa003600.21826271
103Fatty acid elongation_Homo sapiens_hsa000620.20965999
104Viral carcinogenesis_Homo sapiens_hsa052030.19299389
105Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.18906978
106Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.18316384
107Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.17621093
108Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.15145593
109Amphetamine addiction_Homo sapiens_hsa050310.14412540
110Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.13369823
111Taste transduction_Homo sapiens_hsa047420.12767672
112Legionellosis_Homo sapiens_hsa051340.11303233
113Propanoate metabolism_Homo sapiens_hsa006400.11017622
114Dopaminergic synapse_Homo sapiens_hsa047280.10542079
115Herpes simplex infection_Homo sapiens_hsa051680.08929857
116Type I diabetes mellitus_Homo sapiens_hsa049400.08194165
117GABAergic synapse_Homo sapiens_hsa047270.07475938
118Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.06889850
119Peroxisome_Homo sapiens_hsa041460.06783631
120Olfactory transduction_Homo sapiens_hsa047400.06532172
121Thyroid cancer_Homo sapiens_hsa052160.06256223
122Renin-angiotensin system_Homo sapiens_hsa046140.06153304
123Phototransduction_Homo sapiens_hsa047440.03526980
124HTLV-I infection_Homo sapiens_hsa051660.01968162
125Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.01703165
126Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.00781775

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