ABCA2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. This protein is highly expressed in brain tissue and may play a role in macrophage lipid metabolism and neural development. Two transcript variants encoding different isoforms have been found for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1axon ensheathment in central nervous system (GO:0032291)6.60365657
2central nervous system myelination (GO:0022010)6.60365657
3synaptic vesicle maturation (GO:0016188)5.07519863
4positive regulation of synapse maturation (GO:0090129)4.88305191
5locomotory exploration behavior (GO:0035641)4.59251325
6neuronal action potential propagation (GO:0019227)4.43976013
7positive regulation of calcium ion-dependent exocytosis (GO:0045956)4.42721261
8regulation of short-term neuronal synaptic plasticity (GO:0048172)4.38071696
9positive regulation of excitatory postsynaptic membrane potential (GO:2000463)4.24199322
10glycine transport (GO:0015816)4.19877731
11L-amino acid import (GO:0043092)4.15470440
12gamma-aminobutyric acid transport (GO:0015812)4.15304769
13ensheathment of neurons (GO:0007272)4.06704192
14axon ensheathment (GO:0008366)4.06704192
15myelination (GO:0042552)4.06147544
16cellular potassium ion homeostasis (GO:0030007)3.95235171
17sodium ion export (GO:0071436)3.88321423
18synaptic vesicle exocytosis (GO:0016079)3.85379144
19ionotropic glutamate receptor signaling pathway (GO:0035235)3.82599923
20regulation of synapse maturation (GO:0090128)3.82160060
21cell communication by electrical coupling (GO:0010644)3.72841681
22vocalization behavior (GO:0071625)3.71996073
23regulation of synaptic vesicle exocytosis (GO:2000300)3.70573589
24glutamate secretion (GO:0014047)3.68744247
25synaptic vesicle endocytosis (GO:0048488)3.67066388
26adult walking behavior (GO:0007628)3.60388565
27regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)3.56218441
28potassium ion import (GO:0010107)3.54312261
29fatty acid elongation (GO:0030497)3.53348911
30membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.52045960
31neuromuscular process controlling posture (GO:0050884)3.51451226
32transmission of nerve impulse (GO:0019226)3.51336253
33regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act3.47804759
34postsynaptic membrane organization (GO:0001941)3.46745452
35cerebellar granule cell differentiation (GO:0021707)3.46007245
36neurotransmitter secretion (GO:0007269)3.44240290
37regulation of neuronal synaptic plasticity (GO:0048168)3.42343223
38positive regulation of dendritic spine development (GO:0060999)3.38065683
39neuronal ion channel clustering (GO:0045161)3.36849089
40regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)3.36761497
41neuron cell-cell adhesion (GO:0007158)3.35760279
42cerebellar Purkinje cell differentiation (GO:0021702)3.34275871
43glutamate receptor signaling pathway (GO:0007215)3.33327590
44regulation of neurotransmitter secretion (GO:0046928)3.31850387
45synaptic transmission, glutamatergic (GO:0035249)3.31673677
46peptidyl-tyrosine autophosphorylation (GO:0038083)3.31353549
47layer formation in cerebral cortex (GO:0021819)3.28149767
48myelin maintenance (GO:0043217)3.23711457
49long-chain fatty acid biosynthetic process (GO:0042759)3.23271179
50positive regulation of potassium ion transmembrane transporter activity (GO:1901018)3.23063735
51G-protein coupled acetylcholine receptor signaling pathway (GO:0007213)3.21384734
52long-term memory (GO:0007616)3.21259845
53regulation of synaptic vesicle transport (GO:1902803)3.19305025
54regulation of long-term neuronal synaptic plasticity (GO:0048169)3.18937998
55response to methylmercury (GO:0051597)3.18881629
56negative regulation of neurotransmitter transport (GO:0051589)3.18340305
57dendritic spine morphogenesis (GO:0060997)3.16822025
58neuromuscular process controlling balance (GO:0050885)3.15471233
59neuron-neuron synaptic transmission (GO:0007270)3.15440318
60regulation of glutamate receptor signaling pathway (GO:1900449)3.13493816
61establishment of mitochondrion localization (GO:0051654)3.13327269
62negative regulation of dendrite morphogenesis (GO:0050774)3.12638515
63regulation of vesicle fusion (GO:0031338)3.12623432
64long-term synaptic potentiation (GO:0060291)3.11790453
65amino acid import (GO:0043090)3.11560887
66regulation of synapse structural plasticity (GO:0051823)3.10892626
67exploration behavior (GO:0035640)3.09939725
68potassium ion homeostasis (GO:0055075)3.09637470
69cerebellar Purkinje cell layer development (GO:0021680)3.06212635
70neurotransmitter transport (GO:0006836)3.03497733
71mating behavior (GO:0007617)3.02348979
72presynaptic membrane organization (GO:0097090)3.02176901
73neurotransmitter uptake (GO:0001504)3.01568561
74negative regulation of protein localization to cell surface (GO:2000009)3.00700676
75regulation of neurotransmitter transport (GO:0051588)2.99782757
76nerve growth factor signaling pathway (GO:0038180)2.99536334
77positive regulation of Rap GTPase activity (GO:0032854)2.98786192
78dendrite morphogenesis (GO:0048813)2.98418496
79negative regulation of neurotransmitter secretion (GO:0046929)2.97894065
80positive regulation of neurotransmitter secretion (GO:0001956)2.97253150
81positive regulation of membrane potential (GO:0045838)2.97143915
82protein localization to synapse (GO:0035418)2.95552874
83membrane hyperpolarization (GO:0060081)2.94218348
84positive regulation of neurotransmitter transport (GO:0051590)2.93887102
85regulation of ARF protein signal transduction (GO:0032012)2.93879755
86regulation of excitatory postsynaptic membrane potential (GO:0060079)2.91966554
87auditory behavior (GO:0031223)2.88105241
88activation of protein kinase A activity (GO:0034199)2.86503457
89positive regulation of dendrite development (GO:1900006)2.85494184
90regulation of synaptic transmission (GO:0050804)2.83952800
91gamma-aminobutyric acid signaling pathway (GO:0007214)2.83879758
92cytoskeletal anchoring at plasma membrane (GO:0007016)2.83405714
93regulation of voltage-gated calcium channel activity (GO:1901385)2.83327632
94cell communication involved in cardiac conduction (GO:0086065)2.83145200
95regulation of neurotransmitter levels (GO:0001505)2.82395942
96positive regulation of synaptic transmission, dopaminergic (GO:0032226)2.82037328
97negative regulation of amyloid precursor protein catabolic process (GO:1902992)2.81865918
98dendritic spine organization (GO:0097061)2.81015453
99cell communication by electrical coupling involved in cardiac conduction (GO:0086064)2.80788087
100synaptic vesicle docking involved in exocytosis (GO:0016081)2.80229444
101prepulse inhibition (GO:0060134)2.79344238
102membrane tubulation (GO:0097320)2.78994188
103negative regulation of synaptic transmission, GABAergic (GO:0032229)2.76517394
104regulation of postsynaptic membrane potential (GO:0060078)2.74990935
105creatine metabolic process (GO:0006600)2.74719474
106regulation of dendritic spine development (GO:0060998)2.74201262
107regulation of inhibitory postsynaptic membrane potential (GO:0060080)2.73890772
108regulation of dendritic spine morphogenesis (GO:0061001)2.73261854
109neuron recognition (GO:0008038)2.71720370
110dicarboxylic acid transport (GO:0006835)2.71160935
111signal complex assembly (GO:0007172)2.70276753
112regulation of Rap GTPase activity (GO:0032317)2.69942233
113cell differentiation in hindbrain (GO:0021533)2.69875068
114cellular sodium ion homeostasis (GO:0006883)2.69460853
115cell migration in hindbrain (GO:0021535)2.69290233
116negative regulation of synaptic transmission, glutamatergic (GO:0051967)2.69140384
117regulation of ventricular cardiac muscle cell membrane repolarization (GO:0060307)2.68791690
118vesicle docking involved in exocytosis (GO:0006904)2.68789716
119neurotransmitter-gated ion channel clustering (GO:0072578)2.67128064
120positive regulation of potassium ion transport (GO:0043268)2.66963438
121G-protein coupled glutamate receptor signaling pathway (GO:0007216)2.66771409
122regulation of synaptic plasticity (GO:0048167)2.66473172
123presynaptic membrane assembly (GO:0097105)2.63891970
124membrane depolarization during action potential (GO:0086010)2.63885225
125acidic amino acid transport (GO:0015800)2.63557761
126positive regulation of potassium ion transmembrane transport (GO:1901381)2.63485183
127response to auditory stimulus (GO:0010996)2.61963910
128L-glutamate transport (GO:0015813)2.60404291
129regulation of respiratory gaseous exchange by neurological system process (GO:0002087)2.59516272
130negative regulation of axonogenesis (GO:0050771)2.58884618

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human4.33778008
2SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.86586969
3DROSHA_22980978_ChIP-Seq_HELA_Human2.82832683
4SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.77360933
5GBX2_23144817_ChIP-Seq_PC3_Human2.69864898
6JARID2_20064375_ChIP-Seq_MESCs_Mouse2.60857740
7MTF2_20144788_ChIP-Seq_MESCs_Mouse2.51732185
8RNF2_18974828_ChIP-Seq_MESCs_Mouse2.51064624
9EZH2_18974828_ChIP-Seq_MESCs_Mouse2.51064624
10RARB_27405468_Chip-Seq_BRAIN_Mouse2.47324015
11* SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.43537868
12MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human2.35023571
13LXR_22292898_ChIP-Seq_THP-1_Human2.34818676
14SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.26389032
15JARID2_20075857_ChIP-Seq_MESCs_Mouse2.25732749
16REST_21632747_ChIP-Seq_MESCs_Mouse2.22096316
17SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.20897941
18EZH2_27294783_Chip-Seq_ESCs_Mouse2.16402434
19SUZ12_27294783_Chip-Seq_ESCs_Mouse2.15972502
20SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.15215645
21EZH2_27304074_Chip-Seq_ESCs_Mouse2.03270059
22RNF2_27304074_Chip-Seq_ESCs_Mouse1.93747607
23REST_18959480_ChIP-ChIP_MESCs_Mouse1.92855201
24* EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.91440985
25AR_21572438_ChIP-Seq_LNCaP_Human1.90182972
26EED_16625203_ChIP-ChIP_MESCs_Mouse1.87650116
27KDM2B_26808549_Chip-Seq_DND41_Human1.81100498
28ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.77426021
29ZFP281_27345836_Chip-Seq_ESCs_Mouse1.77122355
30IKZF1_21737484_ChIP-ChIP_HCT116_Human1.76233050
31VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.66399174
32RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.62761871
33KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.57388991
34SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.56977819
35SMC4_20622854_ChIP-Seq_HELA_Human1.54382281
36DNAJC2_21179169_ChIP-ChIP_NT2_Human1.50095367
37ERG_21242973_ChIP-ChIP_JURKAT_Human1.49380471
38* TCF7_22412390_ChIP-Seq_EML_Mouse1.48838786
39SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.47544254
40SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.46276878
41RACK7_27058665_Chip-Seq_MCF-7_Human1.44470928
42KDM2B_26808549_Chip-Seq_JURKAT_Human1.41526038
43TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.39253924
44WT1_25993318_ChIP-Seq_PODOCYTE_Human1.36598278
45CREB1_26743006_Chip-Seq_LNCaP_Human1.34815511
46NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.34036766
47CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.33156149
48ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.32409140
49KDM2B_26808549_Chip-Seq_K562_Human1.32012385
50P68_20966046_ChIP-Seq_HELA_Human1.31954537
51SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.31365045
52GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.31253601
53TAF15_26573619_Chip-Seq_HEK293_Human1.30519092
54NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.24161187
55DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.23851076
56CDX2_19796622_ChIP-Seq_MESCs_Mouse1.22303682
57SMAD4_21799915_ChIP-Seq_A2780_Human1.21971166
58PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.21325840
59SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.21249765
60OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.20856846
61RARG_19884340_ChIP-ChIP_MEFs_Mouse1.20220255
62UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.20217744
63OCT4_19829295_ChIP-Seq_ESCs_Human1.19799807
64CREB1_26743006_Chip-Seq_LNCaP-abl_Human1.19326231
65PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.15783534
66GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.15510593
67WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.15460925
68RING1B_27294783_Chip-Seq_ESCs_Mouse1.15288441
69STAT3_23295773_ChIP-Seq_U87_Human1.14787174
70NR3C1_23031785_ChIP-Seq_PC12_Mouse1.14473430
71SOX2_21211035_ChIP-Seq_LN229_Gbm1.14175519
72ESR1_21235772_ChIP-Seq_MCF-7_Human1.11435714
73CTBP1_25329375_ChIP-Seq_LNCAP_Human1.11130916
74SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.10982535
75* EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.09386928
76CTBP2_25329375_ChIP-Seq_LNCAP_Human1.09258882
77SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.08006075
78AR_19668381_ChIP-Seq_PC3_Human1.07484979
79KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.07416750
80TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.06175411
81SA1_27219007_Chip-Seq_ERYTHROID_Human1.05866231
82RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.05286304
83ESR2_21235772_ChIP-Seq_MCF-7_Human1.05282311
84ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.04920186
85CTCF_27219007_Chip-Seq_ERYTHROID_Human1.04677567
86SMAD3_21741376_ChIP-Seq_EPCs_Human1.04337592
87ZNF217_24962896_ChIP-Seq_MCF-7_Human1.03422801
88PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.02084253
89ELK3_25401928_ChIP-Seq_HUVEC_Human1.02057381
90RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.01993625
91AHR_22903824_ChIP-Seq_MCF-7_Human1.01814716
92TET1_21451524_ChIP-Seq_MESCs_Mouse1.01153184
93ESR1_22446102_ChIP-Seq_UTERUS_Mouse0.99882197
94ARNT_22903824_ChIP-Seq_MCF-7_Human0.99735970
95CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human0.99592031
96PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse0.98234268
97TCF4_23295773_ChIP-Seq_U87_Human0.97745661
98CTNNB1_20460455_ChIP-Seq_HCT116_Human0.97275669
99GATA1_19941827_ChIP-Seq_MEL_Mouse0.97147356
100PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse0.96843788
101TP53_23651856_ChIP-Seq_MEFs_Mouse0.96638340
102TRIM28_21343339_ChIP-Seq_HEK293_Human0.96303295
103P53_22127205_ChIP-Seq_FIBROBLAST_Human0.95662528
104SMAD4_21741376_ChIP-Seq_HESCs_Human0.95296276
105TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human0.95135834
106THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse0.95101030
107P300_27058665_Chip-Seq_ZR-75-30cells_Human0.94506614
108RING1B_27294783_Chip-Seq_NPCs_Mouse0.94400977
109TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.94088087
110CTCF_27219007_Chip-Seq_Bcells_Human0.93816132
111TET1_21490601_ChIP-Seq_MESCs_Mouse0.93639952
112MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.93611641
113EP300_21415370_ChIP-Seq_HL-1_Mouse0.92190034
114TFAP2A_17053090_ChIP-ChIP_MCF-7_Human0.91543858
115MYCN_27167114_Chip-Seq_NEUROBLASTOMA_Human0.91371268
116TP53_16413492_ChIP-PET_HCT116_Human0.91222732
117BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.90612760
118PIAS1_25552417_ChIP-Seq_VCAP_Human0.90606086
119* VDR_21846776_ChIP-Seq_THP-1_Human0.89906508
120GATA1_19941826_ChIP-Seq_K562_Human0.89778236
121RUNX1_27514584_Chip-Seq_MCF-7_Human0.89363607
122ESR1_20079471_ChIP-ChIP_T-47D_Human0.89065163
123ZNF274_21170338_ChIP-Seq_K562_Hela0.88035107
124KDM2B_26808549_Chip-Seq_SUP-B15_Human0.88020397
125KLF4_19829295_ChIP-Seq_ESCs_Human0.86933529
126FOXA2_19822575_ChIP-Seq_HepG2_Human0.86304134
127NR0B1_18358816_ChIP-ChIP_MESCs_Mouse0.85321210
128SMAD3_21741376_ChIP-Seq_ESCs_Human0.85147903
129ZFP281_18757296_ChIP-ChIP_E14_Mouse0.84182202
130DPY_21335234_ChIP-Seq_ESCs_Mouse0.83701930
131SETDB1_19884255_ChIP-Seq_MESCs_Mouse0.83246166
132TP63_22573176_ChIP-Seq_HFKS_Human0.83080808
133MITF_21258399_ChIP-Seq_MELANOMA_Human0.82977364
134ZFP57_27257070_Chip-Seq_ESCs_Mouse0.82697644
135TP63_17297297_ChIP-ChIP_HaCaT_Human0.82400743
136ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse0.81774191
137NR3C1_21868756_ChIP-Seq_MCF10A_Human0.81262965
138* OLIG2_26023283_ChIP-Seq_AINV15_Mouse0.81204439
139AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human0.80886585
140YAP1_20516196_ChIP-Seq_MESCs_Mouse0.80847384
141P300_19829295_ChIP-Seq_ESCs_Human0.80759634
142SMAD4_21741376_ChIP-Seq_EPCs_Human0.80520881
143SMAD3_21741376_ChIP-Seq_HESCs_Human0.80086934
144EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse0.79991585
145AR_25329375_ChIP-Seq_VCAP_Human0.79903094
146PRDM14_20953172_ChIP-Seq_ESCs_Human0.78300830

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity5.36735765
2MP0003880_abnormal_central_pattern3.97940597
3MP0004270_analgesia3.66822757
4MP0003635_abnormal_synaptic_transmissio3.56962345
5MP0000920_abnormal_myelination3.39234727
6MP0009046_muscle_twitch3.22774784
7MP0002064_seizures3.16623296
8MP0009745_abnormal_behavioral_response3.04193966
9MP0002272_abnormal_nervous_system3.02792163
10MP0005423_abnormal_somatic_nervous2.92582820
11MP0003329_amyloid_beta_deposits2.77784019
12MP0002822_catalepsy2.71162653
13MP0002063_abnormal_learning/memory/cond2.63887055
14* MP0001486_abnormal_startle_reflex2.61656016
15MP0003690_abnormal_glial_cell2.57406048
16MP0004885_abnormal_endolymph2.49076484
17MP0008569_lethality_at_weaning2.48278594
18MP0002734_abnormal_mechanical_nocicepti2.40133392
19* MP0002572_abnormal_emotion/affect_behav2.29233535
20MP0001968_abnormal_touch/_nociception2.16544954
21MP0004142_abnormal_muscle_tone1.94413076
22MP0001501_abnormal_sleep_pattern1.92611143
23MP0001970_abnormal_pain_threshold1.88853143
24MP0001440_abnormal_grooming_behavior1.86814335
25MP0002067_abnormal_sensory_capabilities1.86417265
26MP0002733_abnormal_thermal_nociception1.83205605
27MP0003633_abnormal_nervous_system1.78317319
28MP0003634_abnormal_glial_cell1.74145133
29MP0004742_abnormal_vestibular_system1.70842759
30MP0000955_abnormal_spinal_cord1.69236228
31MP0000778_abnormal_nervous_system1.67914117
32MP0005386_behavior/neurological_phenoty1.67179635
33MP0004924_abnormal_behavior1.67179635
34MP0003123_paternal_imprinting1.66088651
35MP0002735_abnormal_chemical_nociception1.65359870
36MP0003631_nervous_system_phenotype1.62667243
37MP0002229_neurodegeneration1.61516384
38MP0001529_abnormal_vocalization1.61168453
39MP0009780_abnormal_chondrocyte_physiolo1.60582564
40MP0003632_abnormal_nervous_system1.57325589
41MP0002736_abnormal_nociception_after1.54174813
42* MP0002066_abnormal_motor_capabilities/c1.51884232
43MP0004043_abnormal_pH_regulation1.50485579
44MP0000604_amyloidosis1.49006784
45MP0001905_abnormal_dopamine_level1.46849045
46MP0003705_abnormal_hypodermis_morpholog1.45438418
47* MP0002882_abnormal_neuron_morphology1.42670420
48MP0004811_abnormal_neuron_physiology1.42113064
49MP0002184_abnormal_innervation1.38854581
50MP0004145_abnormal_muscle_electrophysio1.38314632
51MP0002557_abnormal_social/conspecific_i1.33673639
52MP0001485_abnormal_pinna_reflex1.33629420
53MP0002909_abnormal_adrenal_gland1.28781289
54MP0004858_abnormal_nervous_system1.27994245
55MP0005646_abnormal_pituitary_gland1.22248824
56MP0000747_muscle_weakness1.18851526
57MP0001502_abnormal_circadian_rhythm1.17015501
58MP0005409_darkened_coat_color1.13115743
59MP0005551_abnormal_eye_electrophysiolog1.03809980
60MP0003950_abnormal_plasma_membrane1.03343766
61MP0001346_abnormal_lacrimal_gland1.03304047
62MP0002249_abnormal_larynx_morphology1.02864766
63MP0001177_atelectasis1.01930171
64MP0000751_myopathy1.01282481
65MP0008874_decreased_physiological_sensi1.00782184
66MP0005645_abnormal_hypothalamus_physiol0.99776718
67MP0002152_abnormal_brain_morphology0.99454202
68MP0003879_abnormal_hair_cell0.96145745
69MP0003075_altered_response_to0.95716702
70MP0000579_abnormal_nail_morphology0.95351253
71MP0008872_abnormal_physiological_respon0.91581513
72MP0000566_synostosis0.90769678
73MP0003172_abnormal_lysosome_physiology0.89936915
74MP0001299_abnormal_eye_distance/0.89908722
75MP0001963_abnormal_hearing_physiology0.88746844
76MP0000013_abnormal_adipose_tissue0.85708939
77MP0005535_abnormal_body_temperature0.85130004
78MP0008260_abnormal_autophagy0.83733184
79MP0002069_abnormal_eating/drinking_beha0.83432179
80MP0003122_maternal_imprinting0.81069129
81MP0005410_abnormal_fertilization0.81059100
82MP0002752_abnormal_somatic_nervous0.80409703
83MP0003137_abnormal_impulse_conducting0.79979135
84MP0005167_abnormal_blood-brain_barrier0.79959756
85MP0004085_abnormal_heartbeat0.79385605
86MP0004036_abnormal_muscle_relaxation0.79094809
87MP0003283_abnormal_digestive_organ0.78793460
88MP0002089_abnormal_postnatal_growth/wei0.78707617
89MP0001984_abnormal_olfaction0.78649736
90MP0010234_abnormal_vibrissa_follicle0.78093129
91MP0008961_abnormal_basal_metabolism0.77800294
92MP0005623_abnormal_meninges_morphology0.77675873
93MP0002090_abnormal_vision0.73811921
94MP0000003_abnormal_adipose_tissue0.73476661
95MP0005171_absent_coat_pigmentation0.73376022
96MP0006276_abnormal_autonomic_nervous0.70995318
97MP0003045_fibrosis0.69459694
98MP0001849_ear_inflammation0.69286176
99MP0004147_increased_porphyrin_level0.69102050
100MP0000681_abnormal_thyroid_gland0.68519623
101MP0004510_myositis0.67681856
102MP0005058_abnormal_lysosome_morphology0.66265169
103MP0003787_abnormal_imprinting0.66153056
104MP0001958_emphysema0.64884183
105MP0005166_decreased_susceptibility_to0.62057635
106MP0004130_abnormal_muscle_cell0.59055755
107MP0003183_abnormal_peptide_metabolism0.58966101
108MP0003195_calcinosis0.58514639
109MP0001348_abnormal_lacrimal_gland0.56065448
110MP0001943_abnormal_respiration0.55460956
111MP0010678_abnormal_skin_adnexa0.54577246
112MP0001986_abnormal_taste_sensitivity0.54319177
113MP0010769_abnormal_survival0.54273381
114MP0001765_abnormal_ion_homeostasis0.54193653
115MP0005584_abnormal_enzyme/coenzyme_acti0.53504721
116MP0002133_abnormal_respiratory_system0.53493397
117MP0005388_respiratory_system_phenotype0.53493397
118MP0001731_abnormal_postnatal_growth0.51566488
119MP0000639_abnormal_adrenal_gland0.51236314
120MP0010768_mortality/aging0.50069038
121MP0003191_abnormal_cellular_cholesterol0.49672146
122MP0010770_preweaning_lethality0.49616511
123MP0002082_postnatal_lethality0.48971321

Predicted human phenotypes

RankGene SetZ-score
1Myokymia (HP:0002411)5.96827439
2Neurofibrillary tangles (HP:0002185)5.03071280
3Focal motor seizures (HP:0011153)4.97723702
4Action tremor (HP:0002345)4.89456959
5Obstructive sleep apnea (HP:0002870)4.89206144
6Supranuclear gaze palsy (HP:0000605)4.79988427
7Focal seizures (HP:0007359)4.22133909
8Ankle clonus (HP:0011448)4.18527791
9Intention tremor (HP:0002080)4.17405860
10Degeneration of the lateral corticospinal tracts (HP:0002314)4.12759103
11Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)4.12759103
12Abnormality of the corticospinal tract (HP:0002492)4.10139567
13Dysmetria (HP:0001310)4.09483903
14Cerebral inclusion bodies (HP:0100314)4.02477022
15Spastic gait (HP:0002064)3.92950163
16Scanning speech (HP:0002168)3.83790631
17Peripheral hypomyelination (HP:0007182)3.79098901
18Annular pancreas (HP:0001734)3.60520249
19Onion bulb formation (HP:0003383)3.60495658
20Visual hallucinations (HP:0002367)3.59966567
21Progressive cerebellar ataxia (HP:0002073)3.47319159
22Termporal pattern (HP:0011008)3.31794907
23Insidious onset (HP:0003587)3.31794907
24Dysdiadochokinesis (HP:0002075)3.19472792
25Postural instability (HP:0002172)3.11550880
26Atonic seizures (HP:0010819)3.08708884
27Gaze-evoked nystagmus (HP:0000640)3.08405858
28Urinary urgency (HP:0000012)2.96743159
29Broad-based gait (HP:0002136)2.93965498
30Epileptic encephalopathy (HP:0200134)2.93312186
31Truncal ataxia (HP:0002078)2.86744309
32Urinary bladder sphincter dysfunction (HP:0002839)2.81624875
33Hemiplegia (HP:0002301)2.76844051
34Slow saccadic eye movements (HP:0000514)2.75513538
35Depression (HP:0000716)2.74510495
36Pheochromocytoma (HP:0002666)2.73255067
37Anxiety (HP:0000739)2.73181103
38Clonus (HP:0002169)2.71397490
39Abnormality of saccadic eye movements (HP:0000570)2.67207685
40Generalized tonic-clonic seizures (HP:0002069)2.64945470
41Neuronal loss in central nervous system (HP:0002529)2.64915796
42Poor eye contact (HP:0000817)2.62442836
43Lower limb muscle weakness (HP:0007340)2.62110485
44Absence seizures (HP:0002121)2.61739611
45Impaired vibration sensation in the lower limbs (HP:0002166)2.61465093
46Impaired social interactions (HP:0000735)2.58423943
47Abnormal social behavior (HP:0012433)2.58423943
48Dialeptic seizures (HP:0011146)2.57996519
49Sleep apnea (HP:0010535)2.56355965
50Hyperacusis (HP:0010780)2.53047172
51Spastic tetraparesis (HP:0001285)2.52044667
52Abnormality of binocular vision (HP:0011514)2.51613598
53Diplopia (HP:0000651)2.51613598
54Abnormal eating behavior (HP:0100738)2.51277169
55Cerebral hypomyelination (HP:0006808)2.51068939
56Sensory axonal neuropathy (HP:0003390)2.47378561
57Megalencephaly (HP:0001355)2.46505958
58Increased circulating renin level (HP:0000848)2.45447850
59Cerebral aneurysm (HP:0004944)2.43017265
60Torticollis (HP:0000473)2.42480526
61Lower limb amyotrophy (HP:0007210)2.39076979
62Distal upper limb amyotrophy (HP:0007149)2.37303014
63Upper limb amyotrophy (HP:0009129)2.37303014
64Apathy (HP:0000741)2.34911740
65Abnormal auditory evoked potentials (HP:0006958)2.32510824
66Bronchomalacia (HP:0002780)2.31843884
67Hemiparesis (HP:0001269)2.31436797
68Postural tremor (HP:0002174)2.29932186
69Mutism (HP:0002300)2.28692982
70Hammertoe (HP:0001765)2.23611155
71Neuroendocrine neoplasm (HP:0100634)2.23137973
72Febrile seizures (HP:0002373)2.22303615
73Abnormality of the lower motor neuron (HP:0002366)2.22196554
74Dysmetric saccades (HP:0000641)2.19518449
75Rigidity (HP:0002063)2.18810922
76Spinal canal stenosis (HP:0003416)2.18417994
77Lower limb asymmetry (HP:0100559)2.15857918
78Shallow orbits (HP:0000586)2.14653034
79Insomnia (HP:0100785)2.13952497
80Turricephaly (HP:0000262)2.12312667
81Focal dystonia (HP:0004373)2.12178459
82Status epilepticus (HP:0002133)2.11367710
83Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)2.11082771
84Alacrima (HP:0000522)2.11061137
85Impaired smooth pursuit (HP:0007772)2.10853982
86Stridor (HP:0010307)2.10774005
87Pointed chin (HP:0000307)2.09985836
88Psychosis (HP:0000709)2.09729990
89Stereotypic behavior (HP:0000733)2.09388609
90Limb dystonia (HP:0002451)2.08874863
91Delusions (HP:0000746)2.08703871
92Diminished motivation (HP:0000745)2.08317521
93Choreoathetosis (HP:0001266)2.08070730
94Progressive inability to walk (HP:0002505)2.07815274
95Papilledema (HP:0001085)2.07414256
96Genetic anticipation (HP:0003743)2.06631352
97Bundle branch block (HP:0011710)2.03937141
98Craniofacial dystonia (HP:0012179)2.02341067
99Aplasia involving bones of the upper limbs (HP:0009823)2.01359415
100Aplasia of the phalanges of the hand (HP:0009802)2.01359415
101Aplasia involving bones of the extremities (HP:0009825)2.01359415
102Morphological abnormality of the pyramidal tract (HP:0002062)2.01041485
103Metabolic alkalosis (HP:0200114)1.99742322
104Cerebral hemorrhage (HP:0001342)1.99556307
105Abnormality of the periventricular white matter (HP:0002518)1.98796271
106Slow progression (HP:0003677)1.98530181
107Hand muscle atrophy (HP:0009130)1.98482148
108Rapidly progressive (HP:0003678)1.97741348
109Ventricular fibrillation (HP:0001663)1.96937083
110Gait ataxia (HP:0002066)1.96316356
111Foot dorsiflexor weakness (HP:0009027)1.96053635
112Clumsiness (HP:0002312)1.95982272
113Tetraplegia (HP:0002445)1.94674163
114Bradykinesia (HP:0002067)1.94593712
115Akinesia (HP:0002304)1.93690985
116Retinal dysplasia (HP:0007973)1.91891808
117Decreased motor nerve conduction velocity (HP:0003431)1.90595473
118Abnormality of ocular smooth pursuit (HP:0000617)1.90586612
119CNS hypomyelination (HP:0003429)1.88979548
120Difficulty running (HP:0009046)1.88749999
121Epileptiform EEG discharges (HP:0011182)1.87942236
122Distal sensory impairment (HP:0002936)1.86809968
123Generalized myoclonic seizures (HP:0002123)1.86790608
124Macroorchidism (HP:0000053)1.86144298
125Bowel incontinence (HP:0002607)1.83780903
126Broad face (HP:0000283)1.82329386
127Abnormality of the foot musculature (HP:0001436)1.76679057

Predicted kinase interactions (KEA)

RankGene SetZ-score
1STK393.36876257
2NTRK32.88542328
3OXSR12.76944117
4EPHA42.62015129
5TRIB32.44945650
6PAK62.40826598
7MAP3K92.35620159
8NTRK12.32518970
9WNK12.11041050
10EPHB12.08775620
11NTRK21.98077985
12UHMK11.97405761
13MARK11.94592227
14PRKD31.91989424
15CDK191.84367557
16PKN11.82652421
17MAP3K41.77200515
18TNIK1.70433245
19KSR21.70208920
20MAPKAPK51.69999594
21TYRO31.67682926
22MINK11.65072549
23SIK11.58268548
24SGK4941.57938889
25SGK2231.57938889
26PRPF4B1.57168190
27DAPK21.55680422
28FGFR21.51523203
29WNK41.51362700
30CDK51.48672956
31CAMKK11.41046137
32PNCK1.40578516
33PRKCH1.39294853
34LATS21.38940906
35PHKG11.33179909
36PHKG21.33179909
37CAMK2B1.31826439
38MARK21.25808069
39FES1.19562064
40CAMK1G1.18019301
41MAP3K131.17838013
42ROCK21.14898031
43NEK61.10567439
44ICK1.09386662
45MAP2K41.07374649
46CSNK1G21.03883180
47CAMK2D1.03855990
48EEF2K1.02416208
49STK111.02200905
50MAPK121.00989757
51CAMKK20.99119462
52MAP3K20.98583108
53PDPK10.98496158
54DAPK10.98073526
55ALK0.97806035
56CAMK2G0.93627604
57MAP2K70.93147253
58CSNK1A1L0.92677349
59PAK30.92572039
60SMG10.91363931
61RET0.91185283
62RIPK10.89156533
63CAMK2A0.89013601
64CDK150.89000685
65PINK10.88989905
66STK380.88469538
67PRKD10.87215113
68CSNK1G30.86359544
69MAPK130.85842692
70LIMK10.84648588
71PDK10.83990242
72CDK180.82893153
73CDK140.82802962
74MAP3K70.81216770
75TNK20.81080953
76SIK20.80222010
77CAMK10.80170319
78LMTK20.79758272
79SGK20.79515060
80RIPK40.78000025
81MAP3K110.77336953
82CDK11A0.76597968
83BCR0.76065189
84MUSK0.74007770
85FYN0.73882821
86PRKCG0.71686517
87GRK50.67590617
88FGR0.66712684
89PDGFRA0.66518725
90MET0.66187019
91BRSK10.65517925
92SGK30.64411627
93PLK20.64224817
94SGK10.63489675
95TESK10.62225989
96CDC42BPA0.61854720
97DMPK0.60591339
98CAMK1D0.59890840
99ERN10.59162292
100MAP3K10.58775669
101CSNK1G10.58419510
102PRKCQ0.57978583
103FGFR40.55640608
104RPS6KA30.55256919
105IRAK20.54869656
106TAOK10.54356181
107CAMK40.54289647
108MAPK100.51915058
109BMX0.51620026
110PRKD20.51334234
111PRKG20.51190118
112PRKCE0.50763893
113HIPK20.50316387
114PKN20.49643861
115RPS6KA20.48553910
116CLK10.48438224
117PRKG10.47618114
118CDK120.47253530
119JAK10.45223274
120DAPK30.43644561
121BRAF0.43597701
122DYRK1A0.43559424
123ARAF0.43051173
124CASK0.42658665
125PRKCZ0.42559844
126PTK20.40338400
127ERBB20.38722295
128RAF10.38457792

Predicted pathways (KEGG)

RankGene SetZ-score
1Nitrogen metabolism_Homo sapiens_hsa009103.02144031
2Nicotine addiction_Homo sapiens_hsa050332.58971345
3GABAergic synapse_Homo sapiens_hsa047272.53807267
4Glutamatergic synapse_Homo sapiens_hsa047242.45323186
5Synaptic vesicle cycle_Homo sapiens_hsa047212.32724821
6Circadian entrainment_Homo sapiens_hsa047132.25963860
7Morphine addiction_Homo sapiens_hsa050322.19629700
8Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.18769991
9Salivary secretion_Homo sapiens_hsa049701.98385316
10Olfactory transduction_Homo sapiens_hsa047401.96819369
11Long-term potentiation_Homo sapiens_hsa047201.92392840
12Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.92102497
13Gastric acid secretion_Homo sapiens_hsa049711.84508889
14Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.75570940
15Amphetamine addiction_Homo sapiens_hsa050311.70917273
16Dopaminergic synapse_Homo sapiens_hsa047281.66555024
17Insulin secretion_Homo sapiens_hsa049111.63323284
18Long-term depression_Homo sapiens_hsa047301.62401088
19Cholinergic synapse_Homo sapiens_hsa047251.59651806
20Cocaine addiction_Homo sapiens_hsa050301.57672530
21Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.53718320
22Aldosterone synthesis and secretion_Homo sapiens_hsa049251.51783867
23Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.48496170
24Fatty acid elongation_Homo sapiens_hsa000621.46452647
25Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.40951644
26Serotonergic synapse_Homo sapiens_hsa047261.37834946
27Renin secretion_Homo sapiens_hsa049241.37114605
28Taste transduction_Homo sapiens_hsa047421.36859480
29Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.29120084
30Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.27063470
31Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050141.25865552
32Axon guidance_Homo sapiens_hsa043601.25612846
33Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.24107356
34Regulation of lipolysis in adipocytes_Homo sapiens_hsa049231.21115727
35Calcium signaling pathway_Homo sapiens_hsa040201.19798414
36Oxytocin signaling pathway_Homo sapiens_hsa049211.19543720
37Type II diabetes mellitus_Homo sapiens_hsa049301.18368084
38Phosphatidylinositol signaling system_Homo sapiens_hsa040701.16605275
39cAMP signaling pathway_Homo sapiens_hsa040241.16363648
40Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.12241785
41Gap junction_Homo sapiens_hsa045401.11335249
42Steroid biosynthesis_Homo sapiens_hsa001001.11025815
43Phospholipase D signaling pathway_Homo sapiens_hsa040721.07897489
44GnRH signaling pathway_Homo sapiens_hsa049121.07026509
45Pancreatic secretion_Homo sapiens_hsa049721.06464588
46Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.06358620
47Butanoate metabolism_Homo sapiens_hsa006501.04594494
48Thyroid hormone signaling pathway_Homo sapiens_hsa049191.03881794
49Dorso-ventral axis formation_Homo sapiens_hsa043201.02165903
50Histidine metabolism_Homo sapiens_hsa003400.99943067
51Ether lipid metabolism_Homo sapiens_hsa005650.98467500
52Bile secretion_Homo sapiens_hsa049760.97972582
53Vascular smooth muscle contraction_Homo sapiens_hsa042700.96497405
54Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.96338575
55Estrogen signaling pathway_Homo sapiens_hsa049150.88590724
56cGMP-PKG signaling pathway_Homo sapiens_hsa040220.85186982
57Thyroid hormone synthesis_Homo sapiens_hsa049180.84586051
58ErbB signaling pathway_Homo sapiens_hsa040120.83651426
59Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.83448158
60Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.81398102
61mTOR signaling pathway_Homo sapiens_hsa041500.79512142
62Cardiac muscle contraction_Homo sapiens_hsa042600.77224241
63Collecting duct acid secretion_Homo sapiens_hsa049660.74710294
64Endocytosis_Homo sapiens_hsa041440.72290240
65Sphingolipid signaling pathway_Homo sapiens_hsa040710.72000704
66Fatty acid biosynthesis_Homo sapiens_hsa000610.71137166
67Carbohydrate digestion and absorption_Homo sapiens_hsa049730.70886349
68Dilated cardiomyopathy_Homo sapiens_hsa054140.70814162
69Non-small cell lung cancer_Homo sapiens_hsa052230.70805204
70Glucagon signaling pathway_Homo sapiens_hsa049220.70473964
71Endometrial cancer_Homo sapiens_hsa052130.69555222
72Choline metabolism in cancer_Homo sapiens_hsa052310.68922237
73Longevity regulating pathway - mammal_Homo sapiens_hsa042110.67521099
74Renal cell carcinoma_Homo sapiens_hsa052110.66880510
75Insulin signaling pathway_Homo sapiens_hsa049100.66731445
76Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.66590849
77Glycerophospholipid metabolism_Homo sapiens_hsa005640.66352787
78Melanogenesis_Homo sapiens_hsa049160.65649072
79Glioma_Homo sapiens_hsa052140.64403173
80AMPK signaling pathway_Homo sapiens_hsa041520.62865470
81Arginine biosynthesis_Homo sapiens_hsa002200.62216084
82Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.61877491
83Inositol phosphate metabolism_Homo sapiens_hsa005620.61331224
84Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.60350280
85Arginine and proline metabolism_Homo sapiens_hsa003300.58700726
86MAPK signaling pathway_Homo sapiens_hsa040100.57651556
87Ovarian steroidogenesis_Homo sapiens_hsa049130.57177904
88Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.57033331
89Ras signaling pathway_Homo sapiens_hsa040140.56045848
90Vibrio cholerae infection_Homo sapiens_hsa051100.54970142
91Oocyte meiosis_Homo sapiens_hsa041140.54427538
92Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.52839059
93Fatty acid metabolism_Homo sapiens_hsa012120.52478136
94Notch signaling pathway_Homo sapiens_hsa043300.51760752
95Vitamin B6 metabolism_Homo sapiens_hsa007500.51047927
96Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.49916480
97Chronic myeloid leukemia_Homo sapiens_hsa052200.49504084
98Central carbon metabolism in cancer_Homo sapiens_hsa052300.49325444
99Rap1 signaling pathway_Homo sapiens_hsa040150.45044629
100Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.42686192
101SNARE interactions in vesicular transport_Homo sapiens_hsa041300.42093760
102Chemokine signaling pathway_Homo sapiens_hsa040620.41945256
103HIF-1 signaling pathway_Homo sapiens_hsa040660.41388093
104VEGF signaling pathway_Homo sapiens_hsa043700.41175778
105Prion diseases_Homo sapiens_hsa050200.40559567
106beta-Alanine metabolism_Homo sapiens_hsa004100.39169896
107Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.38733922
108Tight junction_Homo sapiens_hsa045300.37881362
109Glycerolipid metabolism_Homo sapiens_hsa005610.37450018
110Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.35253710
111Acute myeloid leukemia_Homo sapiens_hsa052210.35107307
112Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.34790021
113Prolactin signaling pathway_Homo sapiens_hsa049170.34733612
114Mineral absorption_Homo sapiens_hsa049780.34724358
115Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.34110295
116Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.34021764
117AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.33972988
118Adipocytokine signaling pathway_Homo sapiens_hsa049200.33851000
119Neurotrophin signaling pathway_Homo sapiens_hsa047220.32653771
120Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.32634709
121Sphingolipid metabolism_Homo sapiens_hsa006000.32386989
122Amoebiasis_Homo sapiens_hsa051460.32134858
123Leukocyte transendothelial migration_Homo sapiens_hsa046700.32101479
124B cell receptor signaling pathway_Homo sapiens_hsa046620.31067064
125Phototransduction_Homo sapiens_hsa047440.30832026
126Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.29880988
127Platelet activation_Homo sapiens_hsa046110.29426891

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