Rank | Gene Set | Z-score |
---|---|---|
1 | prostate gland growth (GO:0060736) | 8.97607428 |
2 | ovulation from ovarian follicle (GO:0001542) | 7.07309218 |
3 | mammary gland epithelial cell differentiation (GO:0060644) | 7.06063772 |
4 | epithelial cell maturation (GO:0002070) | 6.80256749 |
5 | iron ion import (GO:0097286) | 6.75931566 |
6 | Golgi transport vesicle coating (GO:0048200) | 6.34306051 |
7 | COPI coating of Golgi vesicle (GO:0048205) | 6.34306051 |
8 | short-chain fatty acid metabolic process (GO:0046459) | 6.09009407 |
9 | activation of transmembrane receptor protein tyrosine kinase activity (GO:0007171) | 6.07387174 |
10 | biotin metabolic process (GO:0006768) | 6.05778624 |
11 | mammary gland alveolus development (GO:0060749) | 5.92998776 |
12 | intestinal epithelial cell development (GO:0060576) | 5.15520898 |
13 | negative regulation of platelet-derived growth factor receptor signaling pathway (GO:0010642) | 4.85737327 |
14 | regulation of water loss via skin (GO:0033561) | 4.69546253 |
15 | diol metabolic process (GO:0034311) | 4.49055172 |
16 | regulation of cytokine production involved in inflammatory response (GO:1900015) | 4.41573366 |
17 | establishment of skin barrier (GO:0061436) | 4.13411576 |
18 | sphingoid metabolic process (GO:0046519) | 4.09194539 |
19 | carnitine metabolic process (GO:0009437) | 4.08855359 |
20 | benzene-containing compound metabolic process (GO:0042537) | 3.92964030 |
21 | growth hormone receptor signaling pathway (GO:0060396) | 3.85823461 |
22 | cardiac right ventricle morphogenesis (GO:0003215) | 3.70819135 |
23 | regulation of hippo signaling (GO:0035330) | 3.69297432 |
24 | fatty acid beta-oxidation using acyl-CoA oxidase (GO:0033540) | 3.66969363 |
25 | regulation of platelet-derived growth factor receptor signaling pathway (GO:0010640) | 3.64895732 |
26 | multicellular organismal water homeostasis (GO:0050891) | 3.63757262 |
27 | COPII vesicle coating (GO:0048208) | 3.62235812 |
28 | desmosome organization (GO:0002934) | 3.62003696 |
29 | insulin-like growth factor receptor signaling pathway (GO:0048009) | 3.58634162 |
30 | branching involved in mammary gland duct morphogenesis (GO:0060444) | 3.50983795 |
31 | valine metabolic process (GO:0006573) | 3.50319076 |
32 | NLS-bearing protein import into nucleus (GO:0006607) | 3.46403050 |
33 | regulation of establishment or maintenance of cell polarity (GO:0032878) | 3.45833341 |
34 | keratinocyte development (GO:0003334) | 3.45037240 |
35 | prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis (GO:006052 | 3.42571796 |
36 | water homeostasis (GO:0030104) | 3.40643367 |
37 | positive regulation of keratinocyte differentiation (GO:0045618) | 3.39904879 |
38 | peptidyl-lysine dimethylation (GO:0018027) | 3.38168527 |
39 | regulation of lipoprotein metabolic process (GO:0050746) | 3.37138456 |
40 | regulation of protein localization to cell surface (GO:2000008) | 3.32073025 |
41 | regulation of female receptivity (GO:0045924) | 3.31209357 |
42 | cellular response to growth hormone stimulus (GO:0071378) | 3.30787003 |
43 | amino-acid betaine metabolic process (GO:0006577) | 3.29942314 |
44 | amino-acid betaine transport (GO:0015838) | 3.29325395 |
45 | carnitine transport (GO:0015879) | 3.29325395 |
46 | regulation of clathrin-mediated endocytosis (GO:2000369) | 3.26614059 |
47 | positive regulation of transcription from RNA polymerase III promoter (GO:0045945) | 3.23197210 |
48 | trivalent inorganic anion homeostasis (GO:0072506) | 3.22566391 |
49 | phosphate ion homeostasis (GO:0055062) | 3.22566391 |
50 | ovulation (GO:0030728) | 3.22154937 |
51 | lung lobe morphogenesis (GO:0060463) | 3.18932977 |
52 | glucocorticoid metabolic process (GO:0008211) | 3.18453235 |
53 | retrograde vesicle-mediated transport, Golgi to ER (GO:0006890) | 3.18321022 |
54 | bundle of His cell to Purkinje myocyte communication (GO:0086069) | 3.16198853 |
55 | face development (GO:0060324) | 3.13011149 |
56 | renal system development (GO:0072001) | 3.11106213 |
57 | endocrine hormone secretion (GO:0060986) | 3.08941083 |
58 | regulation of peroxisome proliferator activated receptor signaling pathway (GO:0035358) | 3.04978240 |
59 | branched-chain amino acid metabolic process (GO:0009081) | 3.04847953 |
60 | G1 DNA damage checkpoint (GO:0044783) | 3.02450981 |
61 | cellular modified amino acid catabolic process (GO:0042219) | 3.00702961 |
62 | mitotic G1 DNA damage checkpoint (GO:0031571) | 2.99147281 |
63 | autophagic vacuole fusion (GO:0000046) | 2.97996057 |
64 | branched-chain amino acid catabolic process (GO:0009083) | 2.96994134 |
65 | branching involved in prostate gland morphogenesis (GO:0060442) | 2.94672477 |
66 | surfactant homeostasis (GO:0043129) | 2.94578467 |
67 | exocrine pancreas development (GO:0031017) | 2.93734368 |
68 | lung secretory cell differentiation (GO:0061140) | 2.92651738 |
69 | RNA-dependent DNA replication (GO:0006278) | 2.92472145 |
70 | dicarboxylic acid catabolic process (GO:0043649) | 2.87642490 |
71 | proline metabolic process (GO:0006560) | 2.87009875 |
72 | sex differentiation (GO:0007548) | 2.85620735 |
73 | chemical homeostasis within a tissue (GO:0048875) | 2.84700390 |
74 | embryo implantation (GO:0007566) | 2.83214975 |
75 | carnitine shuttle (GO:0006853) | 2.82657544 |
76 | regulation of fatty acid beta-oxidation (GO:0031998) | 2.82632921 |
77 | regulation of Arp2/3 complex-mediated actin nucleation (GO:0034315) | 2.82323299 |
78 | JAK-STAT cascade involved in growth hormone signaling pathway (GO:0060397) | 2.82258260 |
79 | O-glycan processing (GO:0016266) | 2.82253346 |
80 | sphingosine metabolic process (GO:0006670) | 2.81090715 |
81 | regulation of Golgi to plasma membrane protein transport (GO:0042996) | 2.79130576 |
82 | retina homeostasis (GO:0001895) | 2.77631213 |
83 | ER overload response (GO:0006983) | 2.77501124 |
84 | very long-chain fatty acid metabolic process (GO:0000038) | 2.74997084 |
85 | primary alcohol catabolic process (GO:0034310) | 2.74293502 |
86 | quaternary ammonium group transport (GO:0015697) | 2.74140912 |
87 | dichotomous subdivision of an epithelial terminal unit (GO:0060600) | 2.70934314 |
88 | heparin metabolic process (GO:0030202) | 2.70559849 |
89 | heparin biosynthetic process (GO:0030210) | 2.70559849 |
90 | female mating behavior (GO:0060180) | 2.69582055 |
91 | tight junction assembly (GO:0070830) | 2.69404687 |
92 | linoleic acid metabolic process (GO:0043651) | 2.66842757 |
93 | oocyte development (GO:0048599) | 2.65321534 |
94 | endothelial cell chemotaxis (GO:0035767) | 2.64806080 |
95 | cranial suture morphogenesis (GO:0060363) | 2.64569796 |
96 | copper ion transport (GO:0006825) | 2.64342017 |
97 | ear development (GO:0043583) | 2.62315302 |
98 | vesicle coating (GO:0006901) | 2.58397348 |
99 | lung epithelial cell differentiation (GO:0060487) | 2.58278993 |
100 | DNA methylation involved in gamete generation (GO:0043046) | 2.57367933 |
Rank | Gene Set | Z-score |
---|---|---|
1 | ESR1_21235772_ChIP-Seq_MCF-7_Human | 4.88373957 |
2 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 4.52754869 |
3 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 4.47962227 |
4 | ESR1_15608294_ChIP-ChIP_MCF-7_Human | 4.05488713 |
5 | ELF5_23300383_ChIP-Seq_T47D_Human | 3.84753840 |
6 | ZNF217_24962896_ChIP-Seq_MCF-7_Human | 3.26969918 |
7 | ZNF652_21678463_ChIP-ChIP_ZR75-1_Human | 2.96271412 |
8 | ZNF263_19887448_ChIP-Seq_K562_Human | 2.82837166 |
9 | * GATA3_24758297_ChIP-Seq_MCF-7_Human | 2.69416489 |
10 | KDM5A_27292631_Chip-Seq_BREAST_Human | 2.52731573 |
11 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 2.51718995 |
12 | AR_21909140_ChIP-Seq_LNCAP_Human | 2.50244424 |
13 | RUNX1_27514584_Chip-Seq_MCF-7_Human | 2.45715398 |
14 | FOXM1_26456572_ChIP-Seq_MCF-7_Human | 2.40122847 |
15 | AHR_22903824_ChIP-Seq_MCF-7_Human | 2.37553675 |
16 | TFAP2C_20629094_ChIP-Seq_MCF-7_Human | 2.32729509 |
17 | FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 2.31989539 |
18 | * ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 2.23483472 |
19 | ARNT_22903824_ChIP-Seq_MCF-7_Human | 2.20595962 |
20 | * FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human | 2.15749660 |
21 | * ESR1_20079471_ChIP-ChIP_T-47D_Human | 11.7075179 |
22 | TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse | 1.94237874 |
23 | HOXB7_26014856_ChIP-Seq_BT474_Human | 1.86023149 |
24 | ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse | 1.79259178 |
25 | SOX2_27498859_Chip-Seq_STOMACH_Mouse | 1.78363101 |
26 | FOXA1_25552417_ChIP-Seq_VCAP_Human | 1.76928226 |
27 | * RACK7_27058665_Chip-Seq_MCF-7_Human | 1.75384450 |
28 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 1.74915915 |
29 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.70450223 |
30 | HIF1A_21447827_ChIP-Seq_MCF-7_Human | 1.69636139 |
31 | CHD1_26751641_Chip-Seq_LNCaP_Human | 1.67816831 |
32 | STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse | 1.63735406 |
33 | TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.60395450 |
34 | ESR1_17901129_ChIP-ChIP_LIVER_Mouse | 1.60144072 |
35 | GATA6_25053715_ChIP-Seq_YYC3_Human | 1.59770648 |
36 | * GATA4_25053715_ChIP-Seq_YYC3_Human | 1.58986334 |
37 | FOXO1_23066095_ChIP-Seq_LIVER_Mouse | 1.55224140 |
38 | AR_21915096_ChIP-Seq_LNCaP-1F5_Human | 1.53783891 |
39 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 1.53457157 |
40 | PPARA_22158963_ChIP-Seq_LIVER_Mouse | 1.53346901 |
41 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.50491389 |
42 | RXR_22158963_ChIP-Seq_LIVER_Mouse | 1.32486073 |
43 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.29183701 |
44 | * FOXA1_26743006_Chip-Seq_LNCaP-abl_Human | 1.24214183 |
45 | PKCTHETA_26484144_Chip-Seq_BREAST_Human | 1.12397103 |
46 | PRDM5_23873026_ChIP-Seq_MEFs_Mouse | 1.10748941 |
47 | CLOCK_20551151_ChIP-Seq_293T_Human | 1.07943237 |
48 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.04468732 |
49 | LXR_22158963_ChIP-Seq_LIVER_Mouse | 1.02813312 |
50 | KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.02745142 |
51 | CBP_21632823_ChIP-Seq_H3396_Human | 1.02154012 |
52 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 1.01693116 |
53 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 1.00887925 |
54 | FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human | 0.99469595 |
55 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 0.97689116 |
56 | FOXO3_23340844_ChIP-Seq_DLD1_Human | 0.94960318 |
57 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 0.93413675 |
58 | EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 0.93108845 |
59 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 0.92412193 |
60 | CDX2_20551321_ChIP-Seq_CACO-2_Human | 0.90467771 |
61 | CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human | 0.87904105 |
62 | KLF5_25053715_ChIP-Seq_YYC3_Human | 0.87903418 |
63 | PPAR_26484153_Chip-Seq_NCI-H1993_Human | 0.83128160 |
64 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 0.82606124 |
65 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 0.79348868 |
66 | CREB1_26743006_Chip-Seq_LNCaP-abl_Human | 0.77829505 |
67 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 0.77791085 |
68 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 0.77467509 |
69 | DACH1_20351289_ChIP-Seq_MDA-MB-231_Human | 0.77435267 |
70 | CDX2_22108803_ChIP-Seq_LS180_Human | 0.75525712 |
71 | SREBP2_21459322_ChIP-Seq_LIVER_Mouse | 0.75098623 |
72 | NEUROD2_26341353_ChIP-Seq_CORTEX_Mouse | 0.74740756 |
73 | TRIM28_21343339_ChIP-Seq_HEK293_Human | 0.73861133 |
74 | HTT_18923047_ChIP-ChIP_STHdh_Human | 0.73263776 |
75 | MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human | 0.72934777 |
76 | ATF3_27146783_Chip-Seq_COLON_Human | 0.72528763 |
77 | BCAT_22108803_ChIP-Seq_LS180_Human | 0.72297570 |
78 | SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse | 0.71022017 |
79 | MYCN_18555785_ChIP-Seq_MESCs_Mouse | 0.70569619 |
80 | CREM_20920259_ChIP-Seq_GC1-SPG_Mouse | 0.69666222 |
81 | SOX2_20726797_ChIP-Seq_SW620_Human | 0.69389325 |
82 | P63_26484246_Chip-Seq_KERATINOCYTES_Human | 0.68962748 |
83 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 0.67569206 |
84 | CREB1_26743006_Chip-Seq_LNCaP_Human | 0.67513902 |
85 | KLF4_18555785_Chip-Seq_ESCs_Mouse | 0.67237535 |
86 | AR_21572438_ChIP-Seq_LNCaP_Human | 0.66420709 |
87 | AR_20517297_ChIP-Seq_VCAP_Human | 0.65960250 |
88 | ELK1_19687146_ChIP-ChIP_HELA_Human | 0.64748685 |
89 | KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 0.64544711 |
90 | ZFX_18555785_ChIP-Seq_MESCs_Mouse | 0.63708697 |
91 | ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human | 0.62944841 |
92 | DCP1A_22483619_ChIP-Seq_HELA_Human | 0.62106891 |
93 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 0.61774656 |
94 | SOX17_20123909_ChIP-Seq_XEN_Mouse | 0.61757594 |
95 | NR1I2_20693526_ChIP-Seq_LIVER_Mouse | 0.60526141 |
96 | CTCF_18555785_Chip-Seq_ESCs_Mouse | 0.60207009 |
97 | * FOXA2_19822575_ChIP-Seq_HepG2_Human | 0.59966605 |
98 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 0.59959376 |
99 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 0.59918666 |
100 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 0.59918666 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0002254_reproductive_system_inflammat | 6.87461710 |
2 | MP0001346_abnormal_lacrimal_gland | 5.39725755 |
3 | MP0005248_abnormal_Harderian_gland | 5.01956826 |
4 | MP0004264_abnormal_extraembryonic_tissu | 3.86292924 |
5 | MP0003183_abnormal_peptide_metabolism | 3.79264120 |
6 | MP0010234_abnormal_vibrissa_follicle | 3.59855208 |
7 | MP0005379_endocrine/exocrine_gland_phen | 3.51500407 |
8 | MP0001919_abnormal_reproductive_system | 3.24128759 |
9 | MP0003191_abnormal_cellular_cholesterol | 3.13981595 |
10 | MP0005408_hypopigmentation | 3.06606677 |
11 | MP0002009_preneoplasia | 2.96478218 |
12 | MP0000427_abnormal_hair_cycle | 2.77709934 |
13 | MP0000566_synostosis | 2.71039515 |
14 | MP0005083_abnormal_biliary_tract | 2.70338570 |
15 | MP0001881_abnormal_mammary_gland | 2.64602922 |
16 | MP0000537_abnormal_urethra_morphology | 2.59659991 |
17 | MP0002796_impaired_skin_barrier | 2.51492703 |
18 | MP0003941_abnormal_skin_development | 2.50128185 |
19 | MP0000627_abnormal_mammary_gland | 2.46149697 |
20 | MP0002098_abnormal_vibrissa_morphology | 2.32972173 |
21 | MP0002166_altered_tumor_susceptibility | 2.15709451 |
22 | MP0009780_abnormal_chondrocyte_physiolo | 2.11478777 |
23 | MP0004782_abnormal_surfactant_physiolog | 2.09900231 |
24 | MP0009384_cardiac_valve_regurgitation | 1.90561938 |
25 | MP0002282_abnormal_trachea_morphology | 1.80836096 |
26 | MP0005389_reproductive_system_phenotype | 1.76228762 |
27 | MP0010678_abnormal_skin_adnexa | 1.72742413 |
28 | MP0004233_abnormal_muscle_weight | 1.68106198 |
29 | MP0001666_abnormal_nutrient_absorption | 1.66082942 |
30 | MP0003936_abnormal_reproductive_system | 1.63286574 |
31 | MP0001727_abnormal_embryo_implantation | 1.58573297 |
32 | MP0000383_abnormal_hair_follicle | 1.51794085 |
33 | MP0001765_abnormal_ion_homeostasis | 1.44152148 |
34 | MP0000579_abnormal_nail_morphology | 1.43104209 |
35 | MP0001873_stomach_inflammation | 1.42826558 |
36 | MP0003315_abnormal_perineum_morphology | 1.42352821 |
37 | MP0002006_tumorigenesis | 1.40785251 |
38 | MP0000681_abnormal_thyroid_gland | 1.38440311 |
39 | MP0002909_abnormal_adrenal_gland | 1.36116205 |
40 | MP0005310_abnormal_salivary_gland | 1.33496453 |
41 | MP0005501_abnormal_skin_physiology | 1.32582333 |
42 | MP0005636_abnormal_mineral_homeostasis | 1.30335049 |
43 | MP0000377_abnormal_hair_follicle | 1.23582896 |
44 | MP0002822_catalepsy | 1.20541001 |
45 | MP0002896_abnormal_bone_mineralization | 1.14007343 |
46 | MP0003638_abnormal_response/metabolism_ | 1.04801532 |
47 | MP0005410_abnormal_fertilization | 1.04131902 |
48 | MP0000613_abnormal_salivary_gland | 1.02081931 |
49 | MP0005075_abnormal_melanosome_morpholog | 0.96848405 |
50 | MP0001216_abnormal_epidermal_layer | 0.89828466 |
51 | MP0003693_abnormal_embryo_hatching | 0.88563029 |
52 | MP0001177_atelectasis | 0.86379954 |
53 | MP0001944_abnormal_pancreas_morphology | 0.85664361 |
54 | MP0002160_abnormal_reproductive_system | 0.84304105 |
55 | MP0002877_abnormal_melanocyte_morpholog | 0.82882969 |
56 | MP0008872_abnormal_physiological_respon | 0.75392191 |
57 | MP0002168_other_aberrant_phenotype | 0.75227445 |
58 | MP0008875_abnormal_xenobiotic_pharmacok | 0.73100712 |
59 | MP0002876_abnormal_thyroid_physiology | 0.72640644 |
60 | MP0001664_abnormal_digestion | 0.71131043 |
61 | MP0003868_abnormal_feces_composition | 0.70240673 |
62 | MP0001661_extended_life_span | 0.70231116 |
63 | MP0004019_abnormal_vitamin_homeostasis | 0.69361173 |
64 | MP0002653_abnormal_ependyma_morphology | 0.67059475 |
65 | MP0010329_abnormal_lipoprotein_level | 0.66804351 |
66 | MP0005647_abnormal_sex_gland | 0.65128502 |
67 | MP0001756_abnormal_urination | 0.64877540 |
68 | MP0002938_white_spotting | 0.63379922 |
69 | MP0009053_abnormal_anal_canal | 0.61610541 |
70 | MP0005365_abnormal_bile_salt | 0.61264310 |
71 | MP0004381_abnormal_hair_follicle | 0.60868137 |
72 | MP0005085_abnormal_gallbladder_physiolo | 0.60200852 |
73 | MP0000678_abnormal_parathyroid_gland | 0.58789047 |
74 | MP0005187_abnormal_penis_morphology | 0.57613401 |
75 | MP0005395_other_phenotype | 0.57280438 |
76 | MP0001929_abnormal_gametogenesis | 0.56801487 |
77 | MP0010030_abnormal_orbit_morphology | 0.56468615 |
78 | MP0000371_diluted_coat_color | 0.56193134 |
79 | MP0002693_abnormal_pancreas_physiology | 0.55787882 |
80 | MP0002090_abnormal_vision | 0.54609398 |
81 | MP0000653_abnormal_sex_gland | 0.53975974 |
82 | MP0010352_gastrointestinal_tract_polyps | 0.52907853 |
83 | MP0000367_abnormal_coat/_hair | 0.52655308 |
84 | MP0000647_abnormal_sebaceous_gland | 0.52327800 |
85 | MP0000467_abnormal_esophagus_morphology | 0.51893841 |
86 | MP0003195_calcinosis | 0.51674053 |
87 | MP0001145_abnormal_male_reproductive | 0.51586227 |
88 | MP0003698_abnormal_male_reproductive | 0.49835824 |
89 | MP0000538_abnormal_urinary_bladder | 0.49820356 |
90 | MP0001186_pigmentation_phenotype | 0.49192115 |
91 | MP0006276_abnormal_autonomic_nervous | 0.48171333 |
92 | MP0000762_abnormal_tongue_morphology | 0.47865283 |
93 | MP0010771_integument_phenotype | 0.47173281 |
94 | MP0005220_abnormal_exocrine_pancreas | 0.46966447 |
95 | MP0005058_abnormal_lysosome_morphology | 0.46748965 |
96 | MP0004147_increased_porphyrin_level | 0.45912944 |
97 | MP0005275_abnormal_skin_tensile | 0.44994705 |
98 | MP0003938_abnormal_ear_development | 0.44597680 |
99 | MP0005646_abnormal_pituitary_gland | 0.43953317 |
100 | MP0003699_abnormal_female_reproductive | 0.42072318 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Sparse lateral eyebrow (HP:0005338) | 7.20876816 |
2 | Concave nail (HP:0001598) | 6.87374853 |
3 | Oligomenorrhea (HP:0000876) | 6.22661283 |
4 | Abnormality of nail color (HP:0100643) | 5.30984840 |
5 | Abnormality of the proximal phalanges of the hand (HP:0009834) | 4.77362979 |
6 | Flat capital femoral epiphysis (HP:0003370) | 4.34009097 |
7 | Pili torti (HP:0003777) | 4.31765888 |
8 | Right ventricular cardiomyopathy (HP:0011663) | 3.91448575 |
9 | Testicular atrophy (HP:0000029) | 3.90960580 |
10 | Deep philtrum (HP:0002002) | 3.79784202 |
11 | Infertility (HP:0000789) | 3.72116079 |
12 | Curly hair (HP:0002212) | 3.67434463 |
13 | Ependymoma (HP:0002888) | 3.56795717 |
14 | Menorrhagia (HP:0000132) | 3.52409179 |
15 | Infantile muscular hypotonia (HP:0008947) | 3.49105123 |
16 | Lip pit (HP:0100267) | 3.26895310 |
17 | Flat acetabular roof (HP:0003180) | 3.04586596 |
18 | Exostoses (HP:0100777) | 3.01595411 |
19 | Tubulointerstitial nephritis (HP:0001970) | 3.00010794 |
20 | Abnormality of the epiphyses of the phalanges of the hand (HP:0005920) | 2.94669584 |
21 | Spontaneous abortion (HP:0005268) | 2.86405011 |
22 | Astrocytoma (HP:0009592) | 2.84850690 |
23 | Abnormality of the astrocytes (HP:0100707) | 2.84850690 |
24 | Congenital ichthyosiform erythroderma (HP:0007431) | 2.77396305 |
25 | Septate vagina (HP:0001153) | 2.70239419 |
26 | Germ cell neoplasia (HP:0100728) | 2.62191801 |
27 | Abnormal tarsal ossification (HP:0008369) | 2.61945596 |
28 | Hyperglycinuria (HP:0003108) | 2.59651434 |
29 | Ectropion (HP:0000656) | 2.54289080 |
30 | Abnormality of the epiphyses of the hand (HP:0005924) | 2.54255374 |
31 | Hypoplastic labia majora (HP:0000059) | 2.54059025 |
32 | Partial duplication of thumb phalanx (HP:0009944) | 2.50136941 |
33 | Glioma (HP:0009733) | 2.49945949 |
34 | Abnormal hair laboratory examination (HP:0003328) | 2.44829868 |
35 | Azoospermia (HP:0000027) | 2.43478565 |
36 | Abnormality involving the epiphyses of the upper limbs (HP:0003839) | 2.40898080 |
37 | Back pain (HP:0003418) | 2.37887497 |
38 | Hyperkalemia (HP:0002153) | 2.34449058 |
39 | Abnormal cartilage morphology (HP:0002763) | 2.33812923 |
40 | Gonadotropin excess (HP:0000837) | 2.26501455 |
41 | Prostate neoplasm (HP:0100787) | 2.25356551 |
42 | Aplasia cutis congenita (HP:0001057) | 2.19421592 |
43 | Abnormality of the labia majora (HP:0012881) | 2.19376313 |
44 | Cystic liver disease (HP:0006706) | 2.14298612 |
45 | Abnormality of the phalanges of the hallux (HP:0010057) | 2.12415191 |
46 | Bifid scrotum (HP:0000048) | 2.11452625 |
47 | Amelogenesis imperfecta (HP:0000705) | 2.10045820 |
48 | Partial duplication of the phalanx of hand (HP:0009999) | 2.09742518 |
49 | Cone-shaped epiphyses of the phalanges of the hand (HP:0010230) | 2.09577152 |
50 | Hypotension (HP:0002615) | 2.07729723 |
51 | Abnormality of the distal phalanges of the toes (HP:0010182) | 2.07715016 |
52 | Severe Myopia (HP:0011003) | 2.06490810 |
53 | Testicular neoplasm (HP:0010788) | 2.04747680 |
54 | Hyperammonemia (HP:0001987) | 2.01228192 |
55 | Abnormality of the dental root (HP:0006486) | 2.00843720 |
56 | Taurodontia (HP:0000679) | 2.00843720 |
57 | Abnormality of permanent molar morphology (HP:0011071) | 2.00843720 |
58 | Abnormality of serine family amino acid metabolism (HP:0010894) | 2.00016601 |
59 | Abnormality of glycine metabolism (HP:0010895) | 2.00016601 |
60 | Congenital glaucoma (HP:0001087) | 1.96701159 |
61 | Insidious onset (HP:0003587) | 1.96067683 |
62 | Termporal pattern (HP:0011008) | 1.96067683 |
63 | Abnormality of the renal cortex (HP:0011035) | 1.96011601 |
64 | Pulmonary artery stenosis (HP:0004415) | 1.94543926 |
65 | Cone-rod dystrophy (HP:0000548) | 1.93861661 |
66 | Abnormality of the parathyroid morphology (HP:0011766) | 1.93746094 |
67 | Abnormality of secondary sexual hair (HP:0009888) | 1.91698603 |
68 | Abnormality of the axillary hair (HP:0100134) | 1.91698603 |
69 | Epiphyseal stippling (HP:0010655) | 1.91502042 |
70 | Hypotrichosis (HP:0001006) | 1.91047081 |
71 | Short 1st metacarpal (HP:0010034) | 1.89942019 |
72 | Aplasia/Hypoplasia of the 1st metacarpal (HP:0010026) | 1.89942019 |
73 | Thin bony cortex (HP:0002753) | 1.89362179 |
74 | Capillary hemangiomas (HP:0005306) | 1.88315213 |
75 | Gout (HP:0001997) | 1.87916180 |
76 | Microretrognathia (HP:0000308) | 1.86839609 |
77 | Abnormality of molar (HP:0011077) | 1.85774818 |
78 | Abnormality of molar morphology (HP:0011070) | 1.85774818 |
79 | Renal salt wasting (HP:0000127) | 1.81726545 |
80 | Abnormality of hair growth rate (HP:0011363) | 1.80429189 |
81 | Slow-growing hair (HP:0002217) | 1.80429189 |
82 | Unilateral renal agenesis (HP:0000122) | 1.77349625 |
83 | Abnormality of the labia minora (HP:0012880) | 1.77091367 |
84 | Abdominal distention (HP:0003270) | 1.76519750 |
85 | Chronic sinusitis (HP:0011109) | 1.76160788 |
86 | Abnormal spermatogenesis (HP:0008669) | 1.75884159 |
87 | Abnormality of the dental pulp (HP:0006479) | 1.74975464 |
88 | Hypoplasia of dental enamel (HP:0006297) | 1.74934851 |
89 | Woolly hair (HP:0002224) | 1.72981421 |
90 | Abnormal foot bone ossification (HP:0010675) | 1.71565266 |
91 | Pigmentary retinal degeneration (HP:0001146) | 1.71307071 |
92 | Neonatal death (HP:0003811) | 1.70085441 |
93 | Bell-shaped thorax (HP:0001591) | 1.69098189 |
94 | Calf muscle hypertrophy (HP:0008981) | 1.65726459 |
95 | Hyperactive renin-angiotensin system (HP:0000841) | 1.63041105 |
96 | Progressive cerebellar ataxia (HP:0002073) | 1.61603586 |
97 | Birth length less than 3rd percentile (HP:0003561) | 1.60576397 |
98 | Sparse eyelashes (HP:0000653) | 1.58239392 |
99 | Autoamputation (HP:0001218) | 1.58094771 |
100 | Abnormality of the 1st metacarpal (HP:0010009) | 1.55890104 |
Rank | Gene Set | Z-score |
---|---|---|
1 | TESK1 | 5.32259977 |
2 | EIF2AK1 | 3.95011536 |
3 | FER | 3.54062808 |
4 | LATS1 | 3.13924405 |
5 | PKN2 | 2.98994959 |
6 | STK38L | 2.94928666 |
7 | TSSK6 | 2.83511268 |
8 | TNK2 | 2.67969515 |
9 | EPHA2 | 2.62361735 |
10 | TRIB3 | 2.51719204 |
11 | PNCK | 2.45889055 |
12 | MAPKAPK3 | 2.38272545 |
13 | AKT3 | 2.33362033 |
14 | MATK | 2.01434122 |
15 | EIF2AK3 | 1.98433194 |
16 | BRSK2 | 1.98394197 |
17 | WEE1 | 1.85386505 |
18 | FGFR4 | 1.84401958 |
19 | PRKCI | 1.74099357 |
20 | CDK7 | 1.69045843 |
21 | SIK1 | 1.63357210 |
22 | CDK12 | 1.61372568 |
23 | MET | 1.59444106 |
24 | MST4 | 1.50693043 |
25 | JAK2 | 1.48336994 |
26 | LIMK1 | 1.48233871 |
27 | MST1R | 1.46141053 |
28 | SCYL2 | 1.42919380 |
29 | LATS2 | 1.28467249 |
30 | RIPK1 | 1.25211591 |
31 | ERBB2 | 1.21331793 |
32 | NEK9 | 1.18935663 |
33 | STK39 | 1.17516716 |
34 | RPS6KB2 | 1.14877070 |
35 | INSRR | 0.98927990 |
36 | GRK6 | 0.95435606 |
37 | STK38 | 0.95350579 |
38 | TAF1 | 0.93096273 |
39 | PDGFRB | 0.92418885 |
40 | PRKAA2 | 0.90165120 |
41 | PBK | 0.88675481 |
42 | STK3 | 0.87187160 |
43 | EPHA3 | 0.85078926 |
44 | PTK2 | 0.84587643 |
45 | TAOK3 | 0.83899926 |
46 | CSNK1E | 0.80539167 |
47 | WNK4 | 0.80098475 |
48 | ERBB3 | 0.79269407 |
49 | EEF2K | 0.78193485 |
50 | PAK3 | 0.75222010 |
51 | MUSK | 0.73584272 |
52 | CASK | 0.73180434 |
53 | BMPR2 | 0.72527564 |
54 | ALK | 0.71745133 |
55 | YES1 | 0.69942073 |
56 | MAPK15 | 0.69517261 |
57 | LRRK2 | 0.65955365 |
58 | CHUK | 0.65527355 |
59 | BRSK1 | 0.63719964 |
60 | CAMK1D | 0.60692649 |
61 | SGK2 | 0.58648446 |
62 | MAP2K6 | 0.57199420 |
63 | FRK | 0.56552146 |
64 | AKT2 | 0.56544858 |
65 | MTOR | 0.56500183 |
66 | PTK6 | 0.55830114 |
67 | CAMK1G | 0.55350871 |
68 | TTK | 0.55051012 |
69 | MINK1 | 0.52991626 |
70 | DMPK | 0.52458021 |
71 | NUAK1 | 0.51286764 |
72 | CDK3 | 0.50365191 |
73 | RET | 0.49946998 |
74 | NEK6 | 0.48692544 |
75 | MAP3K3 | 0.48012559 |
76 | ZAP70 | 0.44368462 |
77 | PRKAA1 | 0.43794291 |
78 | NME1 | 0.41100632 |
79 | SGK3 | 0.40117088 |
80 | PRKD1 | 0.37145569 |
81 | PDGFRA | 0.36555196 |
82 | CSNK2A2 | 0.34794911 |
83 | HIPK2 | 0.34052557 |
84 | TESK2 | 0.33028105 |
85 | ILK | 0.32158690 |
86 | OXSR1 | 0.30711819 |
87 | SRPK1 | 0.30578193 |
88 | IGF1R | 0.30340888 |
89 | ATR | 0.29623604 |
90 | CSNK1A1 | 0.28302046 |
91 | SGK1 | 0.27070410 |
92 | MAPK8 | 0.25240474 |
93 | CDK1 | 0.24232023 |
94 | PAK2 | 0.23892670 |
95 | JAK1 | 0.23370200 |
96 | GSK3B | 0.23009043 |
97 | MAP2K1 | 0.22395051 |
98 | ERBB4 | 0.22280126 |
99 | MAPK10 | 0.21975256 |
100 | PAK4 | 0.21813499 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 5.88840708 |
2 | Protein export_Homo sapiens_hsa03060 | 3.16419819 |
3 | Butanoate metabolism_Homo sapiens_hsa00650 | 2.81708702 |
4 | * ABC transporters_Homo sapiens_hsa02010 | 2.79410508 |
5 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 2.75512660 |
6 | Fatty acid elongation_Homo sapiens_hsa00062 | 2.63885620 |
7 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 2.55847020 |
8 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 2.52456995 |
9 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 2.50326007 |
10 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 2.25227276 |
11 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 2.11522001 |
12 | Histidine metabolism_Homo sapiens_hsa00340 | 2.01864084 |
13 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 1.98202801 |
14 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 1.97271783 |
15 | Fatty acid metabolism_Homo sapiens_hsa01212 | 1.92303438 |
16 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.76813593 |
17 | Peroxisome_Homo sapiens_hsa04146 | 1.75290890 |
18 | Sulfur metabolism_Homo sapiens_hsa00920 | 1.73891277 |
19 | Mismatch repair_Homo sapiens_hsa03430 | 1.68837724 |
20 | Homologous recombination_Homo sapiens_hsa03440 | 1.68769573 |
21 | Tyrosine metabolism_Homo sapiens_hsa00350 | 1.65892264 |
22 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 1.61954996 |
23 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 1.53240166 |
24 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.51932319 |
25 | Fatty acid degradation_Homo sapiens_hsa00071 | 1.51544365 |
26 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 1.43785332 |
27 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.40775976 |
28 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.27816609 |
29 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 1.27228522 |
30 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.26871341 |
31 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 1.26741657 |
32 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 1.18947297 |
33 | Steroid biosynthesis_Homo sapiens_hsa00100 | 1.11032918 |
34 | Tryptophan metabolism_Homo sapiens_hsa00380 | 1.06721255 |
35 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 1.05800895 |
36 | Prostate cancer_Homo sapiens_hsa05215 | 1.03688326 |
37 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.02685563 |
38 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.99437830 |
39 | Endometrial cancer_Homo sapiens_hsa05213 | 0.98311724 |
40 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.95852694 |
41 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 0.93762920 |
42 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.93448831 |
43 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.90700789 |
44 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.89956286 |
45 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.89081680 |
46 | Mineral absorption_Homo sapiens_hsa04978 | 0.88732202 |
47 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.87510304 |
48 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 0.86871164 |
49 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.86599400 |
50 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.86379724 |
51 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 0.86212948 |
52 | AMPK signaling pathway_Homo sapiens_hsa04152 | 0.79745177 |
53 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 0.79686760 |
54 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.79677873 |
55 | Circadian rhythm_Homo sapiens_hsa04710 | 0.79269149 |
56 | Bladder cancer_Homo sapiens_hsa05219 | 0.75227587 |
57 | Thyroid cancer_Homo sapiens_hsa05216 | 0.74395680 |
58 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.73630463 |
59 | PPAR signaling pathway_Homo sapiens_hsa03320 | 0.71774004 |
60 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.54610551 |
61 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.53315785 |
62 | RNA transport_Homo sapiens_hsa03013 | 0.53155309 |
63 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 0.49907772 |
64 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.49452133 |
65 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.48860164 |
66 | Metabolic pathways_Homo sapiens_hsa01100 | 0.48037119 |
67 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.47217474 |
68 | Endocytosis_Homo sapiens_hsa04144 | 0.46622580 |
69 | Arginine biosynthesis_Homo sapiens_hsa00220 | 0.46556370 |
70 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.45488186 |
71 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.45158160 |
72 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.44121110 |
73 | Retinol metabolism_Homo sapiens_hsa00830 | 0.42550329 |
74 | Other glycan degradation_Homo sapiens_hsa00511 | 0.40266684 |
75 | Insulin resistance_Homo sapiens_hsa04931 | 0.37993504 |
76 | Lysosome_Homo sapiens_hsa04142 | 0.37924577 |
77 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.36962770 |
78 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 0.36720687 |
79 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.36304188 |
80 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.36275649 |
81 | Sulfur relay system_Homo sapiens_hsa04122 | 0.36269378 |
82 | Renin-angiotensin system_Homo sapiens_hsa04614 | 0.36188363 |
83 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.33171340 |
84 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.33074894 |
85 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 0.32868311 |
86 | Insulin signaling pathway_Homo sapiens_hsa04910 | 0.32192442 |
87 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.32147308 |
88 | DNA replication_Homo sapiens_hsa03030 | 0.30446365 |
89 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 0.30027005 |
90 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.29092182 |
91 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.28005126 |
92 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.27161399 |
93 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.25458602 |
94 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.25237208 |
95 | Lysine degradation_Homo sapiens_hsa00310 | 0.25228410 |
96 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.24756024 |
97 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 0.24402893 |
98 | Hepatitis C_Homo sapiens_hsa05160 | 0.23760735 |
99 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.23015768 |
100 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.22781210 |