Rank | Gene Set | Z-score |
---|---|---|
1 | exogenous drug catabolic process (GO:0042738) | 7.99513530 |
2 | erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222) | 7.61064597 |
3 | L-phenylalanine catabolic process (GO:0006559) | 7.61064597 |
4 | erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221) | 7.26566154 |
5 | L-phenylalanine metabolic process (GO:0006558) | 7.26566154 |
6 | aromatic amino acid family catabolic process (GO:0009074) | 6.85986052 |
7 | epoxygenase P450 pathway (GO:0019373) | 6.65500475 |
8 | triglyceride-rich lipoprotein particle remodeling (GO:0034370) | 6.33760193 |
9 | tryptophan catabolic process (GO:0006569) | 6.25798160 |
10 | indole-containing compound catabolic process (GO:0042436) | 6.25798160 |
11 | indolalkylamine catabolic process (GO:0046218) | 6.25798160 |
12 | kynurenine metabolic process (GO:0070189) | 6.13276021 |
13 | omega-hydroxylase P450 pathway (GO:0097267) | 6.02160540 |
14 | bile acid biosynthetic process (GO:0006699) | 5.97371740 |
15 | tryptophan metabolic process (GO:0006568) | 5.88100541 |
16 | glyoxylate metabolic process (GO:0046487) | 5.75110128 |
17 | urea cycle (GO:0000050) | 5.64310907 |
18 | urea metabolic process (GO:0019627) | 5.64310907 |
19 | alpha-linolenic acid metabolic process (GO:0036109) | 5.63520301 |
20 | negative regulation of fibrinolysis (GO:0051918) | 5.60864175 |
21 | high-density lipoprotein particle remodeling (GO:0034375) | 5.55907119 |
22 | regulation of fibrinolysis (GO:0051917) | 5.45412602 |
23 | protein carboxylation (GO:0018214) | 5.40952863 |
24 | peptidyl-glutamic acid carboxylation (GO:0017187) | 5.40952863 |
25 | regulation of protein activation cascade (GO:2000257) | 5.36428282 |
26 | complement activation, alternative pathway (GO:0006957) | 5.30882378 |
27 | cysteine metabolic process (GO:0006534) | 5.28999960 |
28 | sulfur amino acid catabolic process (GO:0000098) | 5.26818688 |
29 | intestinal cholesterol absorption (GO:0030299) | 5.21781066 |
30 | nitrogen cycle metabolic process (GO:0071941) | 5.18447080 |
31 | bile acid metabolic process (GO:0008206) | 5.11821596 |
32 | serine family amino acid catabolic process (GO:0009071) | 5.11388154 |
33 | drug metabolic process (GO:0017144) | 5.02882196 |
34 | regulation of complement activation (GO:0030449) | 5.00024041 |
35 | aromatic amino acid family metabolic process (GO:0009072) | 4.97833530 |
36 | fatty acid beta-oxidation using acyl-CoA oxidase (GO:0033540) | 4.88848778 |
37 | regulation of cholesterol esterification (GO:0010872) | 4.88670854 |
38 | regulation of plasminogen activation (GO:0010755) | 4.86352344 |
39 | reverse cholesterol transport (GO:0043691) | 4.83648333 |
40 | tyrosine metabolic process (GO:0006570) | 4.78729243 |
41 | regulation of triglyceride catabolic process (GO:0010896) | 4.77929746 |
42 | protein-lipid complex remodeling (GO:0034368) | 4.76077080 |
43 | macromolecular complex remodeling (GO:0034367) | 4.76077080 |
44 | plasma lipoprotein particle remodeling (GO:0034369) | 4.76077080 |
45 | oxidative demethylation (GO:0070989) | 4.72783423 |
46 | homocysteine metabolic process (GO:0050667) | 4.72610906 |
47 | alpha-amino acid catabolic process (GO:1901606) | 4.66296006 |
48 | acylglycerol homeostasis (GO:0055090) | 4.63578930 |
49 | triglyceride homeostasis (GO:0070328) | 4.63578930 |
50 | negative regulation of sterol transport (GO:0032372) | 4.63209308 |
51 | negative regulation of cholesterol transport (GO:0032375) | 4.63209308 |
52 | phospholipid efflux (GO:0033700) | 4.58696134 |
53 | lysine metabolic process (GO:0006553) | 4.58337319 |
54 | lysine catabolic process (GO:0006554) | 4.58337319 |
55 | ethanol metabolic process (GO:0006067) | 4.57562602 |
56 | amino-acid betaine metabolic process (GO:0006577) | 4.55693165 |
57 | imidazole-containing compound metabolic process (GO:0052803) | 4.49211664 |
58 | coenzyme catabolic process (GO:0009109) | 4.44911965 |
59 | cellular ketone body metabolic process (GO:0046950) | 4.43862316 |
60 | bile acid and bile salt transport (GO:0015721) | 4.43617957 |
61 | indolalkylamine metabolic process (GO:0006586) | 4.42660177 |
62 | glycine metabolic process (GO:0006544) | 4.41856853 |
63 | plasma lipoprotein particle clearance (GO:0034381) | 4.36516559 |
64 | negative regulation of hemostasis (GO:1900047) | 4.36132764 |
65 | negative regulation of blood coagulation (GO:0030195) | 4.36132764 |
66 | cellular biogenic amine catabolic process (GO:0042402) | 4.34557303 |
67 | amine catabolic process (GO:0009310) | 4.34557303 |
68 | glutamate metabolic process (GO:0006536) | 4.31155605 |
69 | cellular amino acid catabolic process (GO:0009063) | 4.27695314 |
70 | cellular glucuronidation (GO:0052695) | 4.27127815 |
71 | cholesterol efflux (GO:0033344) | 4.25341301 |
72 | negative regulation of protein activation cascade (GO:2000258) | 4.23755736 |
73 | benzene-containing compound metabolic process (GO:0042537) | 4.17160008 |
74 | serine family amino acid metabolic process (GO:0009069) | 4.16347735 |
75 | ethanol oxidation (GO:0006069) | 4.13368457 |
76 | cellular modified amino acid catabolic process (GO:0042219) | 4.08174643 |
77 | phenylpropanoid metabolic process (GO:0009698) | 4.05198521 |
78 | drug catabolic process (GO:0042737) | 4.03787836 |
79 | regulation of humoral immune response (GO:0002920) | 4.03638953 |
80 | fibrinolysis (GO:0042730) | 4.02815322 |
81 | dicarboxylic acid biosynthetic process (GO:0043650) | 4.02730350 |
82 | low-density lipoprotein particle remodeling (GO:0034374) | 4.02098602 |
83 | plasma lipoprotein particle assembly (GO:0034377) | 4.02043057 |
84 | arginine metabolic process (GO:0006525) | 4.01489820 |
85 | serine family amino acid biosynthetic process (GO:0009070) | 4.00603786 |
86 | negative regulation of coagulation (GO:0050819) | 3.99396035 |
87 | flavonoid metabolic process (GO:0009812) | 3.97006281 |
88 | aldehyde catabolic process (GO:0046185) | 3.95351913 |
89 | alkaloid metabolic process (GO:0009820) | 3.92819517 |
90 | S-adenosylmethionine metabolic process (GO:0046500) | 3.91137883 |
91 | positive regulation of hemostasis (GO:1900048) | 3.88576893 |
92 | positive regulation of blood coagulation (GO:0030194) | 3.88576893 |
93 | regulation of bile acid biosynthetic process (GO:0070857) | 3.86712855 |
94 | blood coagulation, intrinsic pathway (GO:0007597) | 3.85958969 |
95 | acute-phase response (GO:0006953) | 3.84321936 |
96 | ketone body metabolic process (GO:1902224) | 3.84136318 |
97 | cofactor catabolic process (GO:0051187) | 3.82186067 |
98 | very-low-density lipoprotein particle assembly (GO:0034379) | 3.80485372 |
99 | negative regulation of wound healing (GO:0061045) | 3.79405493 |
100 | complement activation, classical pathway (GO:0006958) | 3.79079067 |
101 | glucuronate metabolic process (GO:0019585) | 3.78755593 |
102 | uronic acid metabolic process (GO:0006063) | 3.78755593 |
103 | protein-lipid complex subunit organization (GO:0071825) | 3.78400903 |
104 | regulation of cholesterol homeostasis (GO:2000188) | 3.77484891 |
105 | positive regulation of triglyceride lipase activity (GO:0061365) | 3.76463282 |
106 | positive regulation of lipoprotein lipase activity (GO:0051006) | 3.76463282 |
107 | cholesterol homeostasis (GO:0042632) | 3.75071497 |
108 | complement activation (GO:0006956) | 3.74001444 |
109 | phospholipid homeostasis (GO:0055091) | 3.73554366 |
110 | protein activation cascade (GO:0072376) | 3.73248789 |
111 | positive regulation of lipid catabolic process (GO:0050996) | 3.72904988 |
112 | carboxylic acid catabolic process (GO:0046395) | 3.72693599 |
113 | organic acid catabolic process (GO:0016054) | 3.72693599 |
114 | negative regulation of lipase activity (GO:0060192) | 3.72226326 |
115 | regulation of apoptotic cell clearance (GO:2000425) | 3.71636421 |
116 | sterol homeostasis (GO:0055092) | 3.68971771 |
117 | short-chain fatty acid metabolic process (GO:0046459) | 3.68152618 |
118 | acetyl-CoA metabolic process (GO:0006084) | 3.67013757 |
119 | cytolysis (GO:0019835) | 3.63628371 |
120 | plasma lipoprotein particle organization (GO:0071827) | 3.62644190 |
121 | fat-soluble vitamin biosynthetic process (GO:0042362) | 3.60802013 |
122 | protein-lipid complex assembly (GO:0065005) | 3.60117066 |
123 | NAD biosynthetic process (GO:0009435) | 3.59047082 |
124 | opsonization (GO:0008228) | 3.58411776 |
125 | positive regulation of coagulation (GO:0050820) | 3.58173499 |
126 | intestinal absorption (GO:0050892) | 3.58079733 |
127 | negative regulation of complement activation (GO:0045916) | 3.50720680 |
128 | positive regulation of heterotypic cell-cell adhesion (GO:0034116) | 3.45361519 |
129 | positive regulation of fatty acid biosynthetic process (GO:0045723) | 3.44553705 |
130 | heme transport (GO:0015886) | 3.43448778 |
131 | lipoprotein metabolic process (GO:0042157) | 3.41908530 |
132 | drug transmembrane transport (GO:0006855) | 3.33929083 |
Rank | Gene Set | Z-score |
---|---|---|
1 | RXR_22158963_ChIP-Seq_LIVER_Mouse | 8.41582101 |
2 | PPARA_22158963_ChIP-Seq_LIVER_Mouse | 7.22525388 |
3 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 7.02436305 |
4 | * LXR_22158963_ChIP-Seq_LIVER_Mouse | 6.51413121 |
5 | FOXO1_23066095_ChIP-Seq_LIVER_Mouse | 5.32628716 |
6 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 5.06929915 |
7 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 4.77765282 |
8 | * NR1I2_20693526_ChIP-Seq_LIVER_Mouse | 4.01519194 |
9 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 3.99125561 |
10 | TCF7L2_21901280_ChIP-Seq_H4IIE_Rat | 2.05427698 |
11 | ESR1_17901129_ChIP-ChIP_LIVER_Mouse | 11.9675230 |
12 | TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.92482508 |
13 | * HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 1.92098174 |
14 | CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 1.86253871 |
15 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.71821195 |
16 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.61919963 |
17 | * FOXA2_19822575_ChIP-Seq_HepG2_Human | 1.60912716 |
18 | VDR_22108803_ChIP-Seq_LS180_Human | 1.58584745 |
19 | HTT_18923047_ChIP-ChIP_STHdh_Human | 1.56178362 |
20 | CLOCK_20551151_ChIP-Seq_293T_Human | 1.52515090 |
21 | * HNF4A_19822575_ChIP-Seq_HepG2_Human | 1.40959735 |
22 | GATA1_22025678_ChIP-Seq_K562_Human | 1.40515321 |
23 | FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 1.39292307 |
24 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 1.32537030 |
25 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.22655577 |
26 | GBX2_23144817_ChIP-Seq_PC3_Human | 1.21817298 |
27 | RXRA_24833708_ChIP-Seq_LIVER_Mouse | 1.19826592 |
28 | STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse | 1.17987262 |
29 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 1.16181796 |
30 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 1.16063405 |
31 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.10297869 |
32 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.09121262 |
33 | ESR1_15608294_ChIP-ChIP_MCF-7_Human | 1.07317261 |
34 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 1.05839151 |
35 | ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse | 1.04346994 |
36 | ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 1.02726644 |
37 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 1.02502972 |
38 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.01797092 |
39 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.01267265 |
40 | STAT3_23295773_ChIP-Seq_U87_Human | 1.01126063 |
41 | DROSHA_22980978_ChIP-Seq_HELA_Human | 1.00678195 |
42 | MYC_19829295_ChIP-Seq_ESCs_Human | 0.99666971 |
43 | TP53_16413492_ChIP-PET_HCT116_Human | 0.99577915 |
44 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 0.98854050 |
45 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 0.98402257 |
46 | RAC3_21632823_ChIP-Seq_H3396_Human | 0.97761672 |
47 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 0.97631983 |
48 | TCF4_22108803_ChIP-Seq_LS180_Human | 0.96567437 |
49 | TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse | 0.95601082 |
50 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 0.95479169 |
51 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 0.95479169 |
52 | SOX2_27498859_Chip-Seq_STOMACH_Mouse | 0.94100710 |
53 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 0.93925577 |
54 | NANOG_19829295_ChIP-Seq_ESCs_Human | 0.93333430 |
55 | SOX2_19829295_ChIP-Seq_ESCs_Human | 0.93333430 |
56 | ERA_21632823_ChIP-Seq_H3396_Human | 0.93288999 |
57 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 0.92883184 |
58 | EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 0.91714436 |
59 | * CTBP1_25329375_ChIP-Seq_LNCAP_Human | 0.91254505 |
60 | OCT4_20526341_ChIP-Seq_ESCs_Human | 0.91158605 |
61 | IRF1_19129219_ChIP-ChIP_H3396_Human | 0.90836295 |
62 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 0.90724558 |
63 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 0.90245324 |
64 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 0.87860091 |
65 | * TCF4_23295773_ChIP-Seq_U87_Human | 0.87636715 |
66 | NANOG_20526341_ChIP-Seq_ESCs_Human | 0.87416016 |
67 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 0.86855141 |
68 | PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse | 0.86675382 |
69 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 0.86335106 |
70 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 0.86218831 |
71 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 0.86000894 |
72 | CBP_20019798_ChIP-Seq_JUKART_Human | 0.86000894 |
73 | RARG_19884340_ChIP-ChIP_MEFs_Mouse | 0.84968204 |
74 | TCF4_18268006_ChIP-ChIP_LS174T_Human | 0.84881851 |
75 | EBNA1_20929547_Chip-Seq_RAJI-cells_Human | 0.84840082 |
76 | ZNF652_21678463_ChIP-ChIP_ZR75-1_Human | 0.84266254 |
77 | * NCOR_22424771_ChIP-Seq_293T_Human | 0.83221490 |
78 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 0.83131831 |
79 | SOX2_21211035_ChIP-Seq_LN229_Human | 0.82353929 |
80 | GATA4_25053715_ChIP-Seq_YYC3_Human | 0.81539160 |
81 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 0.81310907 |
82 | SMAD4_21741376_ChIP-Seq_EPCs_Human | 0.80833109 |
83 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 0.79428214 |
84 | * AUTS2_25519132_ChIP-Seq_293T-REX_Human | 0.78492293 |
85 | * GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 0.78087185 |
86 | CRX_20693478_ChIP-Seq_RETINA_Mouse | 0.77389456 |
87 | ESRRB_18555785_ChIP-Seq_MESCs_Mouse | 0.77324631 |
88 | EZH2_22144423_ChIP-Seq_EOC_Human | 0.76017130 |
89 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 0.75270386 |
90 | SREBP2_21459322_ChIP-Seq_LIVER_Mouse | 0.75048903 |
91 | * KAP1_22055183_ChIP-Seq_ESCs_Mouse | 0.75022336 |
92 | FOXH1_21741376_ChIP-Seq_ESCs_Human | 0.74926100 |
93 | RARA_24833708_ChIP-Seq_LIVER_Mouse | 0.73851575 |
94 | ZNF263_19887448_ChIP-Seq_K562_Human | 0.73812291 |
95 | AR_25329375_ChIP-Seq_VCAP_Human | 0.73745582 |
96 | * BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human | 0.72382324 |
97 | Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse | 0.71019194 |
98 | CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse | 0.70487711 |
99 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 0.69099058 |
100 | * SREBP1_19666523_ChIP-Seq_LIVER_Mouse | 0.67875103 |
101 | AR_21915096_ChIP-Seq_LNCaP-1F5_Human | 0.67757362 |
102 | NFE2L2_20460467_ChIP-Seq_MEFs_Mouse | 0.63476606 |
103 | NRF2_20460467_ChIP-Seq_MEFs_Mouse | 0.63476606 |
104 | RARB_24833708_ChIP-Seq_LIVER_Mouse | 0.63247091 |
105 | * SALL4_18804426_ChIP-ChIP_XEN_Mouse | 0.62776202 |
106 | RAD21_21589869_ChIP-Seq_MESCs_Mouse | 0.61356081 |
107 | NR0B1_18358816_ChIP-ChIP_MESCs_Mouse | 0.61102675 |
108 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 0.60986472 |
109 | BMI1_19503595_ChIP-Seq_MEFsC_Mouse | 0.60864650 |
110 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 0.59666013 |
111 | * RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 0.58902527 |
112 | CEBPB_22108803_ChIP-Seq_LS180_Human | 0.56936701 |
113 | LXR_22292898_ChIP-Seq_THP-1_Human | 0.55953520 |
114 | PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse | 0.53845157 |
115 | FOXA1_25552417_ChIP-Seq_VCAP_Human | 0.53261383 |
116 | MYC_19915707_ChIP-ChIP_AK7_Human | 0.52009951 |
117 | EGR1_19032775_ChIP-ChIP_M12_Human | 0.51966923 |
118 | FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human | 0.51054171 |
119 | STAT3_1855785_ChIP-Seq_MESCs_Mouse | 0.50747351 |
120 | FOXA1_26743006_Chip-Seq_LNCaP-abl_Human | 0.50497085 |
121 | AR_20517297_ChIP-Seq_VCAP_Human | 0.50295372 |
122 | ESET_19884257_ChIP-Seq_ESCs_Mouse | 0.48973803 |
123 | STAT1_17558387_ChIP-Seq_HELA_Human | 0.48404890 |
124 | CDX2_20551321_ChIP-Seq_CACO-2_Human | 0.48170945 |
125 | CBP_21632823_ChIP-Seq_H3396_Human | 0.47640293 |
126 | P53_21459846_ChIP-Seq_SAOS-2_Human | 0.46642169 |
127 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 0.46396519 |
128 | ESR1_21235772_ChIP-Seq_MCF-7_Human | 0.46057806 |
129 | TAF15_26573619_Chip-Seq_HEK293_Human | 0.44962189 |
130 | PPARG_20887899_ChIP-Seq_3T3-L1_Mouse | 0.44932357 |
131 | FOXO3_23340844_ChIP-Seq_DLD1_Human | 0.44876664 |
132 | GATA1_19941826_ChIP-Seq_K562_Human | 0.44221061 |
133 | PPARD_23208498_ChIP-Seq_MDA-MB-231_Human | 0.43013575 |
134 | GATA1_19941827_ChIP-Seq_MEL_Mouse | 0.42833660 |
135 | SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse | 0.42232784 |
136 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 0.41946331 |
137 | TAF2_19829295_ChIP-Seq_ESCs_Human | 0.41280128 |
138 | FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human | 0.41199842 |
139 | GATA6_25053715_ChIP-Seq_YYC3_Human | 0.40941857 |
140 | ERG_21242973_ChIP-ChIP_JURKAT_Human | 0.40724726 |
141 | GATA2_19941826_ChIP-Seq_K562_Human | 0.40574114 |
142 | CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse | 0.40550380 |
143 | ESR1_20079471_ChIP-ChIP_T-47D_Human | 0.40221709 |
144 | PPAR_26484153_Chip-Seq_NCI-H1993_Human | 0.40156453 |
145 | BCAT_22108803_ChIP-Seq_LS180_Human | 0.39302580 |
146 | MYC_27129775_Chip-Seq_CORNEA_Mouse | 0.38842747 |
147 | STAT3_19079543_ChIP-ChIP_MESCs_Mouse | 0.38763798 |
148 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 0.38504221 |
149 | LUZP1_20508642_ChIP-Seq_ESCs_Mouse | 0.35596595 |
150 | SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse | 0.35414721 |
151 | SPI1_26923725_Chip-Seq_HPCs_Mouse | 0.35122934 |
152 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 0.34940870 |
153 | CEBPB_26923725_Chip-Seq_MACROPHAGESS_Mouse | 0.34123477 |
154 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 0.33726472 |
155 | CDX2_22108803_ChIP-Seq_LS180_Human | 0.32877921 |
156 | SOX3_22085726_ChIP-Seq_MUSCLE_Mouse | 0.32712137 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0002139_abnormal_hepatobiliary_system | 8.41680108 |
2 | MP0005360_urolithiasis | 7.64796199 |
3 | MP0005085_abnormal_gallbladder_physiolo | 6.54121837 |
4 | MP0005365_abnormal_bile_salt | 6.22704526 |
5 | MP0008875_abnormal_xenobiotic_pharmacok | 5.22718210 |
6 | MP0003806_abnormal_nucleotide_metabolis | 4.29112912 |
7 | MP0003252_abnormal_bile_duct | 3.97441968 |
8 | * MP0010329_abnormal_lipoprotein_level | 3.51469041 |
9 | MP0009840_abnormal_foam_cell | 3.30540515 |
10 | MP0005083_abnormal_biliary_tract | 3.16427402 |
11 | * MP0005332_abnormal_amino_acid | 2.67595520 |
12 | MP0001666_abnormal_nutrient_absorption | 2.65945059 |
13 | MP0003191_abnormal_cellular_cholesterol | 2.30864127 |
14 | MP0000609_abnormal_liver_physiology | 2.19106766 |
15 | MP0004019_abnormal_vitamin_homeostasis | 2.14641179 |
16 | * MP0002118_abnormal_lipid_homeostasis | 2.10182891 |
17 | MP0002138_abnormal_hepatobiliary_system | 1.94061488 |
18 | MP0003868_abnormal_feces_composition | 1.89704429 |
19 | MP0005319_abnormal_enzyme/_coenzyme | 1.84272748 |
20 | MP0001764_abnormal_homeostasis | 1.66486321 |
21 | MP0009697_abnormal_copulation | 1.61862486 |
22 | MP0005584_abnormal_enzyme/coenzyme_acti | 1.57310038 |
23 | MP0005451_abnormal_body_composition | 1.45577968 |
24 | * MP0003195_calcinosis | 1.44313968 |
25 | MP0003011_delayed_dark_adaptation | 1.35192790 |
26 | MP0003656_abnormal_erythrocyte_physiolo | 1.26892806 |
27 | MP0009643_abnormal_urine_homeostasis | 1.23756363 |
28 | MP0003186_abnormal_redox_activity | 1.22399776 |
29 | MP0000598_abnormal_liver_morphology | 1.18717638 |
30 | MP0005647_abnormal_sex_gland | 1.18066237 |
31 | MP0003705_abnormal_hypodermis_morpholog | 1.16268844 |
32 | MP0004043_abnormal_pH_regulation | 1.10148681 |
33 | MP0000604_amyloidosis | 1.09321912 |
34 | MP0000566_synostosis | 1.08960084 |
35 | MP0002254_reproductive_system_inflammat | 1.07422114 |
36 | MP0009764_decreased_sensitivity_to | 1.06817926 |
37 | MP0003122_maternal_imprinting | 1.05294125 |
38 | MP0009763_increased_sensitivity_to | 1.02887944 |
39 | MP0010368_abnormal_lymphatic_system | 1.01757476 |
40 | MP0003879_abnormal_hair_cell | 0.97299878 |
41 | MP0005551_abnormal_eye_electrophysiolog | 0.94542683 |
42 | MP0005636_abnormal_mineral_homeostasis | 0.93918017 |
43 | MP0001986_abnormal_taste_sensitivity | 0.89873636 |
44 | MP0008469_abnormal_protein_level | 0.89069233 |
45 | * MP0009642_abnormal_blood_homeostasis | 0.87022443 |
46 | MP0005408_hypopigmentation | 0.86247823 |
47 | MP0005084_abnormal_gallbladder_morpholo | 0.84193449 |
48 | MP0006036_abnormal_mitochondrial_physio | 0.81248878 |
49 | MP0005376_homeostasis/metabolism_phenot | 0.79954089 |
50 | MP0002909_abnormal_adrenal_gland | 0.78999070 |
51 | MP0009765_abnormal_xenobiotic_induced | 0.78649586 |
52 | MP0002078_abnormal_glucose_homeostasis | 0.78634566 |
53 | MP0002876_abnormal_thyroid_physiology | 0.77622710 |
54 | MP0005670_abnormal_white_adipose | 0.76628465 |
55 | MP0003183_abnormal_peptide_metabolism | 0.76369945 |
56 | MP0002971_abnormal_brown_adipose | 0.74814800 |
57 | MP0005220_abnormal_exocrine_pancreas | 0.73631974 |
58 | MP0003878_abnormal_ear_physiology | 0.73337431 |
59 | MP0005377_hearing/vestibular/ear_phenot | 0.73337431 |
60 | MP0009780_abnormal_chondrocyte_physiolo | 0.72965843 |
61 | MP0005334_abnormal_fat_pad | 0.71248198 |
62 | MP0003690_abnormal_glial_cell | 0.68364683 |
63 | MP0004130_abnormal_muscle_cell | 0.67989200 |
64 | MP0005535_abnormal_body_temperature | 0.67953430 |
65 | MP0001661_extended_life_span | 0.67061042 |
66 | MP0003329_amyloid_beta_deposits | 0.66372998 |
67 | MP0009053_abnormal_anal_canal | 0.66070569 |
68 | MP0005266_abnormal_metabolism | 0.65365558 |
69 | MP0005646_abnormal_pituitary_gland | 0.64947678 |
70 | MP0003646_muscle_fatigue | 0.63305345 |
71 | MP0000639_abnormal_adrenal_gland | 0.60300701 |
72 | MP0002282_abnormal_trachea_morphology | 0.59312818 |
73 | MP0001756_abnormal_urination | 0.59149425 |
74 | MP0005448_abnormal_energy_balance | 0.57586130 |
75 | MP0002822_catalepsy | 0.57241332 |
76 | MP0006035_abnormal_mitochondrial_morpho | 0.57190476 |
77 | MP0005464_abnormal_platelet_physiology | 0.53152063 |
78 | MP0002089_abnormal_postnatal_growth/wei | 0.50041597 |
79 | MP0002928_abnormal_bile_duct | 0.48732021 |
80 | MP0003718_maternal_effect | 0.48421673 |
81 | MP0003638_abnormal_response/metabolism_ | 0.48325054 |
82 | MP0008874_decreased_physiological_sensi | 0.47810209 |
83 | MP0001915_intracranial_hemorrhage | 0.47355957 |
84 | MP0001501_abnormal_sleep_pattern | 0.47315499 |
85 | MP0005410_abnormal_fertilization | 0.45838430 |
86 | MP0003724_increased_susceptibility_to | 0.45534349 |
87 | MP0001324_abnormal_eye_pigmentation | 0.45220801 |
88 | MP0003950_abnormal_plasma_membrane | 0.44374123 |
89 | MP0008873_increased_physiological_sensi | 0.44284046 |
90 | MP0004782_abnormal_surfactant_physiolog | 0.44059209 |
91 | MP0003172_abnormal_lysosome_physiology | 0.43740973 |
92 | MP0003436_decreased_susceptibility_to | 0.43365626 |
93 | * MP0002136_abnormal_kidney_physiology | 0.41670804 |
94 | MP0003953_abnormal_hormone_level | 0.41663207 |
95 | MP0003075_altered_response_to | 0.41365337 |
96 | MP0005248_abnormal_Harderian_gland | 0.40919119 |
97 | MP0005379_endocrine/exocrine_gland_phen | 0.40410502 |
98 | MP0004381_abnormal_hair_follicle | 0.40409518 |
99 | MP0005166_decreased_susceptibility_to | 0.39782468 |
100 | MP0000579_abnormal_nail_morphology | 0.39773470 |
101 | MP0008872_abnormal_physiological_respon | 0.39637861 |
102 | MP0002837_dystrophic_cardiac_calcinosis | 0.39601553 |
103 | MP0006292_abnormal_olfactory_placode | 0.39303483 |
104 | MP0004142_abnormal_muscle_tone | 0.39083340 |
105 | MP0004133_heterotaxia | 0.38893426 |
106 | * MP0002168_other_aberrant_phenotype | 0.37176879 |
107 | MP0009672_abnormal_birth_weight | 0.36839962 |
108 | MP0001765_abnormal_ion_homeostasis | 0.36829957 |
109 | MP0001944_abnormal_pancreas_morphology | 0.36237161 |
110 | MP0005666_abnormal_adipose_tissue | 0.35961983 |
111 | * MP0005395_other_phenotype | 0.35295098 |
112 | MP0002796_impaired_skin_barrier | 0.34585407 |
113 | MP0009384_cardiac_valve_regurgitation | 0.34306275 |
114 | MP0009115_abnormal_fat_cell | 0.33770499 |
115 | MP0006082_CNS_inflammation | 0.33583006 |
116 | MP0000249_abnormal_blood_vessel | 0.32847746 |
117 | MP0001243_abnormal_dermal_layer | 0.32442595 |
118 | MP0005058_abnormal_lysosome_morphology | 0.32283184 |
119 | MP0002970_abnormal_white_adipose | 0.31545448 |
120 | MP0000230_abnormal_systemic_arterial | 0.31212530 |
121 | MP0004883_abnormal_blood_vessel | 0.31023889 |
122 | MP0009785_altered_susceptibility_to | 0.30978080 |
123 | MP0001853_heart_inflammation | 0.29906383 |
124 | MP0001881_abnormal_mammary_gland | 0.28796731 |
125 | MP0001845_abnormal_inflammatory_respons | 0.27124509 |
126 | MP0002132_abnormal_respiratory_system | 0.26685597 |
127 | MP0005167_abnormal_blood-brain_barrier | 0.25247165 |
128 | MP0002060_abnormal_skin_morphology | 0.24593550 |
129 | MP0005164_abnormal_response_to | 0.24396781 |
130 | MP0000427_abnormal_hair_cycle | 0.22812504 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Deep venous thrombosis (HP:0002625) | 7.52844162 |
2 | Abnormality of aromatic amino acid family metabolism (HP:0004338) | 7.51015298 |
3 | Intrahepatic cholestasis (HP:0001406) | 7.40088454 |
4 | Abnormality of monocarboxylic acid metabolism (HP:0010996) | 6.75028904 |
5 | Prolonged partial thromboplastin time (HP:0003645) | 6.73235232 |
6 | Hypobetalipoproteinemia (HP:0003563) | 6.50280332 |
7 | Xanthomatosis (HP:0000991) | 6.33200047 |
8 | Hyperlipoproteinemia (HP:0010980) | 5.60188615 |
9 | Complement deficiency (HP:0004431) | 5.42685360 |
10 | Joint hemorrhage (HP:0005261) | 4.89129476 |
11 | Hypolipoproteinemia (HP:0010981) | 4.84416547 |
12 | Hyperammonemia (HP:0001987) | 4.61431608 |
13 | Epidermoid cyst (HP:0200040) | 4.60412011 |
14 | Abnormality of the common coagulation pathway (HP:0010990) | 4.54396283 |
15 | Hyperglycinemia (HP:0002154) | 4.51728040 |
16 | Abnormality of the level of lipoprotein cholesterol (HP:0010979) | 4.41782104 |
17 | Ketosis (HP:0001946) | 4.29692098 |
18 | Abnormality of sulfur amino acid metabolism (HP:0004339) | 4.25428393 |
19 | Abnormality of methionine metabolism (HP:0010901) | 4.25234740 |
20 | Hypoalphalipoproteinemia (HP:0003233) | 4.22505469 |
21 | Fat malabsorption (HP:0002630) | 4.19534709 |
22 | Abnormality of glutamine family amino acid metabolism (HP:0010902) | 4.17894691 |
23 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 4.10027754 |
24 | Abnormality of glycine metabolism (HP:0010895) | 3.99049921 |
25 | Abnormality of serine family amino acid metabolism (HP:0010894) | 3.99049921 |
26 | Hyperglycinuria (HP:0003108) | 3.98886310 |
27 | Abnormality of complement system (HP:0005339) | 3.96178724 |
28 | Hypoglycemic coma (HP:0001325) | 3.90737688 |
29 | Conjugated hyperbilirubinemia (HP:0002908) | 3.88141145 |
30 | Abnormality of pyrimidine metabolism (HP:0004353) | 3.84369709 |
31 | Abnormality of the intrinsic pathway (HP:0010989) | 3.82983560 |
32 | Hypercholesterolemia (HP:0003124) | 3.71621889 |
33 | Hyperbilirubinemia (HP:0002904) | 3.39762962 |
34 | Abnormality of long-chain fatty-acid metabolism (HP:0010964) | 3.35397040 |
35 | Abnormality of fatty-acid metabolism (HP:0004359) | 3.31670741 |
36 | Delayed CNS myelination (HP:0002188) | 3.17080058 |
37 | Spontaneous abortion (HP:0005268) | 3.14910594 |
38 | Steatorrhea (HP:0002570) | 3.14734907 |
39 | Hypochromic microcytic anemia (HP:0004840) | 3.11376725 |
40 | Abnormality of nucleobase metabolism (HP:0010932) | 3.08955664 |
41 | Abnormality of serum amino acid levels (HP:0003112) | 3.07429188 |
42 | Ketoacidosis (HP:0001993) | 3.05996534 |
43 | Hepatocellular carcinoma (HP:0001402) | 3.01080489 |
44 | Skin nodule (HP:0200036) | 2.81490565 |
45 | Systemic lupus erythematosus (HP:0002725) | 2.78655346 |
46 | Metabolic acidosis (HP:0001942) | 2.77152097 |
47 | Abnormality of purine metabolism (HP:0004352) | 2.71248642 |
48 | Osteomalacia (HP:0002749) | 2.69887238 |
49 | Arthropathy (HP:0003040) | 2.67373879 |
50 | Fair hair (HP:0002286) | 2.63476331 |
51 | Acanthocytosis (HP:0001927) | 2.61931743 |
52 | Lethargy (HP:0001254) | 2.59660613 |
53 | Dicarboxylic aciduria (HP:0003215) | 2.56512789 |
54 | Abnormality of dicarboxylic acid metabolism (HP:0010995) | 2.56512789 |
55 | Hypoglycemic seizures (HP:0002173) | 2.56111126 |
56 | Abnormality of urine glucose concentration (HP:0011016) | 2.55269797 |
57 | Glycosuria (HP:0003076) | 2.55269797 |
58 | Abnormal gallbladder morphology (HP:0012437) | 2.52805738 |
59 | Glomerulonephritis (HP:0000099) | 2.48897228 |
60 | Cholelithiasis (HP:0001081) | 2.46950151 |
61 | Spastic diplegia (HP:0001264) | 2.46147587 |
62 | Gout (HP:0001997) | 2.46087964 |
63 | Cerebral edema (HP:0002181) | 2.39181864 |
64 | Cholecystitis (HP:0001082) | 2.38610769 |
65 | Abnormal gallbladder physiology (HP:0012438) | 2.38610769 |
66 | Irritability (HP:0000737) | 2.36939334 |
67 | Neonatal onset (HP:0003623) | 2.36040591 |
68 | Facial shape deformation (HP:0011334) | 2.36006194 |
69 | Potter facies (HP:0002009) | 2.36006194 |
70 | Malnutrition (HP:0004395) | 2.35935976 |
71 | Purpura (HP:0000979) | 2.35317421 |
72 | Amyloidosis (HP:0011034) | 2.33892060 |
73 | Recurrent gram-negative bacterial infections (HP:0005420) | 2.33638169 |
74 | * Rickets (HP:0002748) | 2.27662256 |
75 | Gingival bleeding (HP:0000225) | 2.26340610 |
76 | * Hemorrhage of the eye (HP:0011885) | 2.24830211 |
77 | Esophageal varix (HP:0002040) | 2.24075970 |
78 | Late onset (HP:0003584) | 2.20231011 |
79 | Menorrhagia (HP:0000132) | 2.19713010 |
80 | Hypothermia (HP:0002045) | 2.16763578 |
81 | Brushfield spots (HP:0001088) | 2.16491428 |
82 | * Myocardial infarction (HP:0001658) | 2.15229076 |
83 | Sensorimotor neuropathy (HP:0007141) | 2.14815587 |
84 | Pancreatitis (HP:0001733) | 2.13698939 |
85 | Thrombophlebitis (HP:0004418) | 2.13423251 |
86 | Enlarged kidneys (HP:0000105) | 2.12757970 |
87 | Poikilocytosis (HP:0004447) | 2.10705338 |
88 | Abnormal biliary tract physiology (HP:0012439) | 2.10094177 |
89 | Bile duct proliferation (HP:0001408) | 2.10094177 |
90 | Hyperinsulinemic hypoglycemia (HP:0000825) | 2.08707547 |
91 | Vomiting (HP:0002013) | 2.07389930 |
92 | Opisthotonus (HP:0002179) | 2.07061387 |
93 | Pigmentary retinal degeneration (HP:0001146) | 2.06325248 |
94 | Abnormality of the gallbladder (HP:0005264) | 2.05307894 |
95 | Hyperphosphaturia (HP:0003109) | 2.02715898 |
96 | Generalized aminoaciduria (HP:0002909) | 2.00490551 |
97 | Bifid scrotum (HP:0000048) | 1.98590098 |
98 | Abnormality of iron homeostasis (HP:0011031) | 1.97443097 |
99 | Abnormality of transition element cation homeostasis (HP:0011030) | 1.94723446 |
100 | Proximal tubulopathy (HP:0000114) | 1.93802482 |
101 | Hydroxyprolinuria (HP:0003080) | 1.89915103 |
102 | Abnormality of proline metabolism (HP:0010907) | 1.89915103 |
103 | Abnormal cartilage morphology (HP:0002763) | 1.87301687 |
104 | Generalized hypopigmentation of hair (HP:0011358) | 1.86726810 |
105 | Renal cortical cysts (HP:0000803) | 1.84420206 |
106 | Status epilepticus (HP:0002133) | 1.83568700 |
107 | Abnormal enzyme/coenzyme activity (HP:0012379) | 1.82534404 |
108 | Elevated hepatic transaminases (HP:0002910) | 1.82290597 |
109 | Alkalosis (HP:0001948) | 1.81684760 |
110 | Hypochromic anemia (HP:0001931) | 1.80491059 |
111 | Hyperglycemia (HP:0003074) | 1.80386128 |
112 | Reticulocytosis (HP:0001923) | 1.79432745 |
113 | Nephritis (HP:0000123) | 1.78271964 |
114 | Abnormal urine phosphate concentration (HP:0012599) | 1.77147300 |
115 | Reduced antithrombin III activity (HP:0001976) | 1.75306056 |
116 | Abnormality of vitamin metabolism (HP:0100508) | 1.74277823 |
117 | Gangrene (HP:0100758) | 1.72835139 |
118 | Joint swelling (HP:0001386) | 1.70079746 |
119 | Pulmonary embolism (HP:0002204) | 1.69462937 |
120 | Acute hepatic failure (HP:0006554) | 1.69349467 |
121 | Symptomatic seizures (HP:0011145) | 1.66527319 |
122 | Retinal atrophy (HP:0001105) | 1.65906895 |
123 | Increased purine levels (HP:0004368) | 1.65053291 |
124 | Hyperuricemia (HP:0002149) | 1.65053291 |
125 | Cerebral palsy (HP:0100021) | 1.64847623 |
126 | Increased serum ferritin (HP:0003281) | 1.64845593 |
127 | * Vascular calcification (HP:0004934) | 1.62146009 |
128 | Widely patent fontanelles and sutures (HP:0004492) | 1.55480279 |
129 | Neoplasm of the liver (HP:0002896) | 1.55155036 |
130 | Azoospermia (HP:0000027) | 1.52153673 |
131 | Chronic hepatic failure (HP:0100626) | 1.45131222 |
132 | Abnormality of the renal cortex (HP:0011035) | 1.44365954 |
Rank | Gene Set | Z-score |
---|---|---|
1 | BCKDK | 6.96048262 |
2 | FGFR4 | 4.75166839 |
3 | SIK1 | 4.74680211 |
4 | ERN1 | 4.40261117 |
5 | TAOK3 | 3.35153130 |
6 | WNK4 | 3.29203094 |
7 | INSRR | 3.03742087 |
8 | ERBB4 | 2.94486229 |
9 | ACVR1B | 2.53516157 |
10 | ADRBK2 | 2.43234604 |
11 | MAP2K4 | 2.32136564 |
12 | PKN2 | 2.12992644 |
13 | WNK3 | 2.09261541 |
14 | MST1R | 2.08395890 |
15 | TLK1 | 1.88630977 |
16 | MAPK11 | 1.87761489 |
17 | FLT3 | 1.84020974 |
18 | PIK3CG | 1.80709605 |
19 | TYK2 | 1.70665748 |
20 | TRIB3 | 1.70081450 |
21 | DAPK2 | 1.68684499 |
22 | MAP4K2 | 1.68591845 |
23 | LATS1 | 1.61652972 |
24 | MAPKAPK3 | 1.57512854 |
25 | BMPR1B | 1.57340216 |
26 | PTK6 | 1.52120769 |
27 | NTRK3 | 1.42060686 |
28 | ABL2 | 1.41139844 |
29 | FGFR2 | 1.38156514 |
30 | KDR | 1.37119455 |
31 | FRK | 1.35854603 |
32 | CAMKK2 | 1.30375185 |
33 | NEK9 | 1.28208248 |
34 | JAK2 | 1.24069944 |
35 | MAP3K7 | 1.20578441 |
36 | PRKAA2 | 1.14929891 |
37 | GRK6 | 1.08305261 |
38 | MAPK15 | 1.07384221 |
39 | ERBB2 | 1.07073805 |
40 | CASK | 1.06697675 |
41 | PINK1 | 1.06455289 |
42 | TBK1 | 1.03727148 |
43 | STK39 | 1.03250812 |
44 | MAP2K3 | 1.03157211 |
45 | JAK1 | 1.02710412 |
46 | BCR | 1.00944755 |
47 | FER | 1.00250048 |
48 | MAP3K14 | 0.98862568 |
49 | MAP3K10 | 0.98235939 |
50 | MAP3K4 | 0.97108726 |
51 | MAPK4 | 0.96963571 |
52 | ZAK | 0.92777543 |
53 | PRKCZ | 0.92563329 |
54 | EPHB1 | 0.87649071 |
55 | NLK | 0.87621910 |
56 | WNK1 | 0.87047511 |
57 | SIK2 | 0.86559559 |
58 | OXSR1 | 0.86235442 |
59 | MET | 0.83960728 |
60 | CDK6 | 0.81836792 |
61 | STK38L | 0.81041687 |
62 | MAPK12 | 0.80795252 |
63 | MAP3K3 | 0.78812866 |
64 | DYRK1B | 0.78298028 |
65 | TIE1 | 0.77925310 |
66 | EPHA3 | 0.77261847 |
67 | MAPK13 | 0.76303388 |
68 | PRKG1 | 0.75725671 |
69 | MATK | 0.75347406 |
70 | PRKACG | 0.75062876 |
71 | MAP3K11 | 0.74998574 |
72 | PRKACA | 0.73506210 |
73 | CAMK1D | 0.72592258 |
74 | OBSCN | 0.72116892 |
75 | CSK | 0.71935421 |
76 | TXK | 0.70517837 |
77 | MAP2K6 | 0.70408585 |
78 | CAMK2G | 0.69637352 |
79 | RIPK1 | 0.66975597 |
80 | PRKAA1 | 0.66620500 |
81 | CHUK | 0.66407856 |
82 | GSK3A | 0.66382085 |
83 | IRAK3 | 0.64524721 |
84 | SGK3 | 0.63105236 |
85 | EPHA4 | 0.60664360 |
86 | NUAK1 | 0.60508897 |
87 | ADRBK1 | 0.59798503 |
88 | PDK2 | 0.59682367 |
89 | SGK1 | 0.59398429 |
90 | PRKCE | 0.59295881 |
91 | MAP3K2 | 0.58782876 |
92 | TGFBR2 | 0.58061225 |
93 | PTK2 | 0.57973705 |
94 | MAPK7 | 0.57791767 |
95 | FGFR3 | 0.55098407 |
96 | TNK2 | 0.54135299 |
97 | CSF1R | 0.53683432 |
98 | IKBKE | 0.53218485 |
99 | FGFR1 | 0.52890200 |
100 | MAP3K9 | 0.52488691 |
101 | PDPK1 | 0.50983013 |
102 | PRKCQ | 0.50707391 |
103 | IKBKB | 0.50555377 |
104 | CSNK1D | 0.48904929 |
105 | CSNK1G1 | 0.47175930 |
106 | SGK2 | 0.46806481 |
107 | GRK1 | 0.46135142 |
108 | TAOK2 | 0.45028054 |
109 | MAP3K13 | 0.44947247 |
110 | IGF1R | 0.43089965 |
111 | ICK | 0.43039983 |
112 | BRSK2 | 0.42593742 |
113 | NME1 | 0.42183732 |
114 | RET | 0.41948220 |
115 | PKN1 | 0.41439334 |
116 | MAP3K5 | 0.40941192 |
117 | MAP2K1 | 0.40084338 |
118 | STK16 | 0.39568052 |
119 | CDK4 | 0.39479243 |
120 | PRKCG | 0.38875174 |
121 | CDK12 | 0.38113656 |
122 | MTOR | 0.36658738 |
123 | KIT | 0.35636097 |
124 | MAP3K6 | 0.35348041 |
125 | CSNK1A1 | 0.35045579 |
126 | STK38 | 0.34992189 |
127 | CAMK4 | 0.33824122 |
128 | SGK223 | 0.32699061 |
129 | SGK494 | 0.32699061 |
130 | EGFR | 0.32168996 |
131 | PDK1 | 0.29928718 |
132 | MAP3K1 | 0.29657118 |
133 | CAMK1G | 0.27756502 |
134 | PBK | 0.27051719 |
135 | CSNK1G2 | 0.26890613 |
136 | PRKCA | 0.26197310 |
137 | PIK3CA | 0.25276335 |
138 | LATS2 | 0.24936008 |
139 | CSNK1G3 | 0.23027715 |
140 | IRAK1 | 0.22819262 |
141 | PAK3 | 0.21484115 |
142 | IRAK2 | 0.21112978 |
143 | ABL1 | 0.20788262 |
144 | MAP2K2 | 0.20702960 |
145 | AKT3 | 0.20585807 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 4.54145311 |
2 | Nitrogen metabolism_Homo sapiens_hsa00910 | 3.57125593 |
3 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 3.37996709 |
4 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 3.32982842 |
5 | Arginine biosynthesis_Homo sapiens_hsa00220 | 3.06445119 |
6 | Complement and coagulation cascades_Homo sapiens_hsa04610 | 2.78656221 |
7 | Tryptophan metabolism_Homo sapiens_hsa00380 | 2.71299185 |
8 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 2.71220982 |
9 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 2.63240580 |
10 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 2.54364446 |
11 | Fatty acid degradation_Homo sapiens_hsa00071 | 2.47236550 |
12 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 2.37296921 |
13 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 2.27683896 |
14 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 2.16902893 |
15 | Butanoate metabolism_Homo sapiens_hsa00650 | 2.15636465 |
16 | Peroxisome_Homo sapiens_hsa04146 | 2.06481974 |
17 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 1.97263061 |
18 | Histidine metabolism_Homo sapiens_hsa00340 | 1.95913896 |
19 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 1.94436096 |
20 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 1.93691896 |
21 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.90260038 |
22 | PPAR signaling pathway_Homo sapiens_hsa03320 | 1.85929755 |
23 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 1.79488192 |
24 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 1.78924088 |
25 | Fatty acid metabolism_Homo sapiens_hsa01212 | 1.78513574 |
26 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.75884254 |
27 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 1.73780403 |
28 | Retinol metabolism_Homo sapiens_hsa00830 | 1.72151330 |
29 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 1.70636579 |
30 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 1.65659998 |
31 | Selenocompound metabolism_Homo sapiens_hsa00450 | 1.59301939 |
32 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.59138368 |
33 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 1.54354889 |
34 | Bile secretion_Homo sapiens_hsa04976 | 1.52513061 |
35 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 1.50496803 |
36 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.47522458 |
37 | Tyrosine metabolism_Homo sapiens_hsa00350 | 1.44646671 |
38 | Pyruvate metabolism_Homo sapiens_hsa00620 | 1.35901946 |
39 | Sulfur metabolism_Homo sapiens_hsa00920 | 1.32649690 |
40 | Fatty acid elongation_Homo sapiens_hsa00062 | 1.30090991 |
41 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 1.29109817 |
42 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 1.28275799 |
43 | Folate biosynthesis_Homo sapiens_hsa00790 | 1.21583097 |
44 | Steroid biosynthesis_Homo sapiens_hsa00100 | 1.20423189 |
45 | Fat digestion and absorption_Homo sapiens_hsa04975 | 1.18161683 |
46 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 1.18126699 |
47 | Carbon metabolism_Homo sapiens_hsa01200 | 1.10336123 |
48 | * ABC transporters_Homo sapiens_hsa02010 | 1.08842964 |
49 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 1.05578549 |
50 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 1.03170849 |
51 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 1.02336198 |
52 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.98869309 |
53 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.97774221 |
54 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.96858742 |
55 | Sulfur relay system_Homo sapiens_hsa04122 | 0.92839688 |
56 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 0.86606464 |
57 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.86180457 |
58 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.85993741 |
59 | Lysine degradation_Homo sapiens_hsa00310 | 0.82247413 |
60 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.78255719 |
61 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.69728535 |
62 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.67891490 |
63 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.64660452 |
64 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.53662740 |
65 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.52669892 |
66 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 0.47411177 |
67 | Metabolic pathways_Homo sapiens_hsa01100 | 0.45303214 |
68 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.44567831 |
69 | Mineral absorption_Homo sapiens_hsa04978 | 0.37069091 |
70 | Prion diseases_Homo sapiens_hsa05020 | 0.35132157 |
71 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.30282778 |
72 | Galactose metabolism_Homo sapiens_hsa00052 | 0.26566414 |
73 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.26391379 |
74 | Pertussis_Homo sapiens_hsa05133 | 0.24772167 |
75 | Insulin resistance_Homo sapiens_hsa04931 | 0.24170135 |
76 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.22053269 |
77 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.21842567 |
78 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.21812580 |
79 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 0.21508195 |
80 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.21394570 |
81 | Other glycan degradation_Homo sapiens_hsa00511 | 0.18988165 |
82 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.18082673 |
83 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.16122973 |
84 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.12237118 |
85 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 0.10627191 |
86 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.07292314 |
87 | Circadian rhythm_Homo sapiens_hsa04710 | 0.03551651 |
88 | AMPK signaling pathway_Homo sapiens_hsa04152 | 0.01935614 |
89 | Amoebiasis_Homo sapiens_hsa05146 | -0.2415550 |
90 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | -0.2363150 |
91 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | -0.2339508 |
92 | Bladder cancer_Homo sapiens_hsa05219 | -0.2251976 |
93 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | -0.2112075 |
94 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | -0.2109538 |
95 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | -0.1983032 |
96 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | -0.1883780 |
97 | Renin-angiotensin system_Homo sapiens_hsa04614 | -0.1771542 |
98 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | -0.1733261 |
99 | Hepatitis C_Homo sapiens_hsa05160 | -0.1728701 |
100 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | -0.1581155 |
101 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | -0.1506045 |
102 | Regulation of autophagy_Homo sapiens_hsa04140 | -0.1495666 |
103 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | -0.1449694 |
104 | Taste transduction_Homo sapiens_hsa04742 | -0.1353811 |
105 | African trypanosomiasis_Homo sapiens_hsa05143 | -0.1349163 |
106 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | -0.1278381 |
107 | Insulin signaling pathway_Homo sapiens_hsa04910 | -0.1001649 |
108 | Protein digestion and absorption_Homo sapiens_hsa04974 | -0.0963897 |
109 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | -0.0865740 |
110 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | -0.0862553 |
111 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | -0.0608453 |
112 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | -0.0480514 |
113 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | -0.0462708 |
114 | Phototransduction_Homo sapiens_hsa04744 | -0.0393199 |
115 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | -0.0113823 |