ABCE1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the OABP subfamily. Alternatively referred to as the RNase L inhibitor, this protein functions to block the activity of ribonuclease L. Activation of ribonuclease L leads to inhibition of protein synthesis in the 2-5A/RNase L system, the central pathway for viral interferon action. Two transcript variants encoding the same protein have been found for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1nuclear pore organization (GO:0006999)6.21136932
2nuclear pore complex assembly (GO:0051292)5.89176671
3DNA unwinding involved in DNA replication (GO:0006268)5.33733924
4establishment of integrated proviral latency (GO:0075713)5.04730207
5folic acid-containing compound biosynthetic process (GO:0009396)4.93114482
6protein localization to kinetochore (GO:0034501)4.92312188
7nucleobase biosynthetic process (GO:0046112)4.87641401
8IMP biosynthetic process (GO:0006188)4.76430627
9mitotic nuclear envelope disassembly (GO:0007077)4.70528740
10nuclear envelope disassembly (GO:0051081)4.43352226
11membrane disassembly (GO:0030397)4.43352226
12purine nucleobase biosynthetic process (GO:0009113)4.37230071
13pore complex assembly (GO:0046931)4.35885308
14DNA replication initiation (GO:0006270)4.33025761
15DNA replication-dependent nucleosome assembly (GO:0006335)4.31600148
16DNA replication-dependent nucleosome organization (GO:0034723)4.31600148
17IMP metabolic process (GO:0046040)4.21290025
18double-strand break repair via nonhomologous end joining (GO:0006303)4.18187198
19non-recombinational repair (GO:0000726)4.18187198
20ribosome assembly (GO:0042255)4.14204972
21mitotic metaphase plate congression (GO:0007080)4.08802252
22DNA strand elongation involved in DNA replication (GO:0006271)4.08244109
23formation of translation preinitiation complex (GO:0001731)4.03013048
24DNA duplex unwinding (GO:0032508)3.96924109
25DNA geometric change (GO:0032392)3.93997404
26protein localization to chromosome, centromeric region (GO:0071459)3.92777082
27DNA strand elongation (GO:0022616)3.88115593
28regulation of translational termination (GO:0006449)3.79789905
29establishment of viral latency (GO:0019043)3.77074389
30regulation of spindle organization (GO:0090224)3.72395385
31DNA ligation (GO:0006266)3.71628728
32mitotic chromosome condensation (GO:0007076)3.64733716
33metaphase plate congression (GO:0051310)3.64614154
34regulation of attachment of spindle microtubules to kinetochore (GO:0051988)3.61682924
35mitotic sister chromatid cohesion (GO:0007064)3.61354377
36DNA topological change (GO:0006265)3.60706322
37DNA double-strand break processing (GO:0000729)3.60245491
38regulation of translational fidelity (GO:0006450)3.59371627
39proteasome assembly (GO:0043248)3.56971684
40sister chromatid segregation (GO:0000819)3.56671557
41negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)3.54397956
42regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450913.53600393
43telomere maintenance via semi-conservative replication (GO:0032201)3.53025943
44ribosome biogenesis (GO:0042254)3.49758444
45tRNA aminoacylation for protein translation (GO:0006418)3.48500958
46regulation of mitotic spindle organization (GO:0060236)3.48184936
47positive regulation of chromosome segregation (GO:0051984)3.47629865
48maturation of SSU-rRNA (GO:0030490)3.46070087
49DNA replication checkpoint (GO:0000076)3.45395002
50tRNA aminoacylation (GO:0043039)3.43761592
51amino acid activation (GO:0043038)3.43761592
52chromatin remodeling at centromere (GO:0031055)3.41631765
53mitotic sister chromatid segregation (GO:0000070)3.39163874
54attachment of spindle microtubules to kinetochore (GO:0008608)3.38880137
55regulation of sister chromatid segregation (GO:0033045)3.37400923
56regulation of mitotic sister chromatid separation (GO:0010965)3.37400923
57regulation of mitotic sister chromatid segregation (GO:0033047)3.37400923
58nuclear envelope organization (GO:0006998)3.37295403
59mitotic recombination (GO:0006312)3.36144939
60chromatin assembly (GO:0031497)3.36134681
61somatic hypermutation of immunoglobulin genes (GO:0016446)3.34057634
62somatic diversification of immune receptors via somatic mutation (GO:0002566)3.34057634
63dosage compensation (GO:0007549)3.33276340
64heterochromatin organization (GO:0070828)3.32395605
65regulation of histone H3-K9 methylation (GO:0051570)3.29962211
66CENP-A containing nucleosome assembly (GO:0034080)3.29795454
67regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)3.29023977
68negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)3.28801182
69regulation of centrosome cycle (GO:0046605)3.28139186
70telomere maintenance via recombination (GO:0000722)3.26845023
71anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:03.26587457
72protein complex localization (GO:0031503)3.25915756
73nucleotide-excision repair, DNA gap filling (GO:0006297)3.23164815
74kinetochore organization (GO:0051383)3.22734802
75establishment of chromosome localization (GO:0051303)3.21584880
76chaperone-mediated protein complex assembly (GO:0051131)3.21102869
77DNA replication-independent nucleosome assembly (GO:0006336)3.21067630
78DNA replication-independent nucleosome organization (GO:0034724)3.21067630
79DNA catabolic process, exonucleolytic (GO:0000738)3.20433923
80maturation of 5.8S rRNA (GO:0000460)3.19675156
81RNA-dependent DNA replication (GO:0006278)3.18281160
82regulation of DNA endoreduplication (GO:0032875)3.17555265
83chromatin assembly or disassembly (GO:0006333)3.16980342
84folic acid metabolic process (GO:0046655)3.15816991
85cellular protein complex localization (GO:0034629)3.15657767
86regulation of centriole replication (GO:0046599)3.14328465
87regulation of gene silencing by RNA (GO:0060966)3.14224330
88regulation of posttranscriptional gene silencing (GO:0060147)3.14224330
89regulation of gene silencing by miRNA (GO:0060964)3.14224330
90mitochondrial RNA metabolic process (GO:0000959)3.10839840
91DNA conformation change (GO:0071103)3.10737129
92spindle checkpoint (GO:0031577)3.09188026
93positive regulation of mitotic metaphase/anaphase transition (GO:0045842)3.09179803
94positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)3.09179803
95positive regulation of mitotic sister chromatid separation (GO:1901970)3.09179803
96pre-miRNA processing (GO:0031054)3.08768984
97regulation of translation in response to stress (GO:0043555)3.08522651
98somatic diversification of immunoglobulins involved in immune response (GO:0002208)3.08100349
99isotype switching (GO:0045190)3.08100349
100somatic recombination of immunoglobulin genes involved in immune response (GO:0002204)3.08100349
101regulation of chromosome segregation (GO:0051983)3.07327032
102postreplication repair (GO:0006301)3.06932004
103chromosome segregation (GO:0007059)3.06125104
104telomere maintenance (GO:0000723)3.05151385
105negative regulation of ubiquitin-protein transferase activity (GO:0051444)3.04331793
106negative regulation of ligase activity (GO:0051352)3.04331793
107negative regulation of histone methylation (GO:0031061)3.03676392
108negative regulation of DNA-dependent DNA replication (GO:2000104)3.03425561
109telomere organization (GO:0032200)3.03221726
110ribonucleoprotein complex biogenesis (GO:0022613)3.02352236
111mitotic spindle checkpoint (GO:0071174)3.01749026
112regulation of mitotic metaphase/anaphase transition (GO:0030071)3.01721882
113mRNA transport (GO:0051028)3.01713740
114regulation of RNA export from nucleus (GO:0046831)3.01634367
115peptidyl-arginine omega-N-methylation (GO:0035247)3.01430935
116spindle assembly checkpoint (GO:0071173)3.01167741
117ribosomal large subunit biogenesis (GO:0042273)3.00848475
118regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.00539326
119regulation of helicase activity (GO:0051095)3.00141875
120negative regulation of chromosome segregation (GO:0051985)2.99361121
121tetrahydrofolate metabolic process (GO:0046653)2.99349530
122regulation of sister chromatid cohesion (GO:0007063)2.97652033
123negative regulation of mitotic sister chromatid separation (GO:2000816)2.96842704
124negative regulation of mitotic sister chromatid segregation (GO:0033048)2.96842704
125negative regulation of mitotic metaphase/anaphase transition (GO:0045841)2.96842704
126negative regulation of sister chromatid segregation (GO:0033046)2.96842704
127mitotic spindle assembly checkpoint (GO:0007094)2.95830397
128telomere maintenance via telomere lengthening (GO:0010833)2.94772744
129spliceosomal tri-snRNP complex assembly (GO:0000244)2.94620148
130histone H2A monoubiquitination (GO:0035518)2.93294734
131negative regulation of mRNA splicing, via spliceosome (GO:0048025)2.93014474
132regulation of metaphase/anaphase transition of cell cycle (GO:1902099)2.92708484
133histone exchange (GO:0043486)2.91730763
134protein localization to chromosome (GO:0034502)2.89143501
135translesion synthesis (GO:0019985)2.86313437

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human9.49398376
2FOXM1_23109430_ChIP-Seq_U2OS_Human4.55836219
3* MYC_18555785_ChIP-Seq_MESCs_Mouse4.27803038
4E2F4_17652178_ChIP-ChIP_JURKAT_Human3.95016757
5* EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.45185174
6* MYC_19079543_ChIP-ChIP_MESCs_Mouse3.06713229
7FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.97782226
8EGR1_19374776_ChIP-ChIP_THP-1_Human2.95454028
9FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.88367498
10* MYC_19030024_ChIP-ChIP_MESCs_Mouse2.78185723
11* KDM5B_21448134_ChIP-Seq_MESCs_Mouse2.63974375
12NELFA_20434984_ChIP-Seq_ESCs_Mouse2.52761798
13AR_21909140_ChIP-Seq_LNCAP_Human2.46689886
14* MYC_18358816_ChIP-ChIP_MESCs_Mouse2.40750328
15EST1_17652178_ChIP-ChIP_JURKAT_Human2.24829390
16E2F1_21310950_ChIP-Seq_MCF-7_Human2.22424185
17KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.19057376
18CREB1_15753290_ChIP-ChIP_HEK293T_Human2.18908594
19MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse2.13943638
20XRN2_22483619_ChIP-Seq_HELA_Human2.11232202
21ETS1_20019798_ChIP-Seq_JURKAT_Human2.09722426
22GABP_17652178_ChIP-ChIP_JURKAT_Human2.07878037
23RBPJ_22232070_ChIP-Seq_NCS_Mouse2.02183492
24* MYBL2_22936984_ChIP-ChIP_MESCs_Mouse2.01407373
25MYCN_18555785_ChIP-Seq_MESCs_Mouse1.97262520
26CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.92355268
27* PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.87415848
28MYC_22102868_ChIP-Seq_BL_Human1.86756078
29VDR_23849224_ChIP-Seq_CD4+_Human1.83953700
30POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.81322797
31* JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.77331976
32SALL1_21062744_ChIP-ChIP_HESCs_Human1.77228932
33ELK1_19687146_ChIP-ChIP_HELA_Human1.77089076
34HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.76936257
35* E2F1_18555785_ChIP-Seq_MESCs_Mouse1.73823659
36* ZFX_18555785_ChIP-Seq_MESCs_Mouse1.70551422
37FOXP3_21729870_ChIP-Seq_TREG_Human1.65349078
38SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.64600771
39POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.58608861
40* YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.58463885
41NANOG_18555785_ChIP-Seq_MESCs_Mouse1.56378981
42NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.52740615
43DCP1A_22483619_ChIP-Seq_HELA_Human1.52359814
44GABP_19822575_ChIP-Seq_HepG2_Human1.49566229
45KDM5A_27292631_Chip-Seq_BREAST_Human1.49530312
46TTF2_22483619_ChIP-Seq_HELA_Human1.47018473
47STAT3_1855785_ChIP-Seq_MESCs_Mouse1.46093626
48ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.42380746
49ELF1_17652178_ChIP-ChIP_JURKAT_Human1.38951496
50ESR1_15608294_ChIP-ChIP_MCF-7_Human1.36693163
51PADI4_21655091_ChIP-ChIP_MCF-7_Human1.34364687
52SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.34305717
53TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.33195374
54SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.33027196
55CIITA_25753668_ChIP-Seq_RAJI_Human1.31515554
56HOXB4_20404135_ChIP-ChIP_EML_Mouse1.30143887
57* SRF_21415370_ChIP-Seq_HL-1_Mouse1.28994136
58E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.28857008
59* THAP11_20581084_ChIP-Seq_MESCs_Mouse1.27768932
60* FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.26138738
61KLF4_18555785_ChIP-Seq_MESCs_Mouse1.25894520
62* ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.24868106
63TFEB_21752829_ChIP-Seq_HELA_Human1.23083139
64SOX2_18555785_ChIP-Seq_MESCs_Mouse1.22077145
65POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.17609754
66NOTCH1_21737748_ChIP-Seq_TLL_Human1.16157217
67CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.12917492
68ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.12456138
69HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.11389580
70KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.10104288
71KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.10104288
72KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.10104288
73CNOT3_19339689_ChIP-ChIP_MESCs_Mouse1.09541200
74SOX17_20123909_ChIP-Seq_XEN_Mouse1.08605144
75* CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.08517671
76PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.07678275
77SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.07101438
78* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.06922452
79ERG_20887958_ChIP-Seq_HPC-7_Mouse1.06607288
80E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.06242026
81TCF3_18692474_ChIP-Seq_MEFs_Mouse1.05924687
82KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.05847464
83HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.05274443
84SOX2_19030024_ChIP-ChIP_MESCs_Mouse1.04650351
85EWS_26573619_Chip-Seq_HEK293_Human1.03563693
86DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.02175931
87NANOG_16153702_ChIP-ChIP_HESCs_Human1.01520016
88NOTCH1_17114293_ChIP-ChIP_T-ALL_Human0.99698321
89NANOG_21062744_ChIP-ChIP_HESCs_Human0.99449572
90TP63_19390658_ChIP-ChIP_HaCaT_Human0.97255822
91CLOCK_20551151_ChIP-Seq_293T_Human0.96817642
92ZFP281_18358816_ChIP-ChIP_MESCs_Mouse0.95005157
93KLF4_18358816_ChIP-ChIP_MESCs_Mouse0.94949844
94NANOG_18700969_ChIP-ChIP_MESCs_Mouse0.94787624
95ZNF263_19887448_ChIP-Seq_K562_Human0.93362308
96MYCN_21190229_ChIP-Seq_SHEP-21N_Human0.93311837
97* CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse0.91385106
98NACC1_18358816_ChIP-ChIP_MESCs_Mouse0.90289546
99YY1_21170310_ChIP-Seq_MESCs_Mouse0.89230934
100PRDM5_23873026_ChIP-Seq_MEFs_Mouse0.89060175
101* CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.88984578
102SALL4_18804426_ChIP-ChIP_MESCs_Mouse0.88351052
103CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human0.88050805
104CHD1_26751641_Chip-Seq_LNCaP_Human0.85504055
105FUS_26573619_Chip-Seq_HEK293_Human0.85000802
106HNF4A_19761587_ChIP-ChIP_CACO-2_Human0.84653700
107HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.84412638
108BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.82184157
109ZIC3_20872845_ChIP-ChIP_MESCs_Mouse0.82058170
110MYC_18940864_ChIP-ChIP_HL60_Human0.81124278
111CEBPB_23403033_ChIP-Seq_LIVER_Mouse0.80272032
112TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse0.80242441
113TCF3_18692474_ChIP-Seq_MESCs_Mouse0.79559749
114* TRIM28_19339689_ChIP-ChIP_MESCs_Mouse0.79542970
115DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.79208634
116GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.78882756
117ELK1_22589737_ChIP-Seq_MCF10A_Human0.76090668
118SOX2_16153702_ChIP-ChIP_HESCs_Human0.75601582
119EOMES_20176728_ChIP-ChIP_TSCs_Mouse0.70537499
120ELF5_23300383_ChIP-Seq_T47D_Human0.69949519
121FLI1_27457419_Chip-Seq_LIVER_Mouse0.68145720
122RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse0.66464174

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching4.21369294
2MP0010094_abnormal_chromosome_stability4.04521557
3MP0004957_abnormal_blastocyst_morpholog3.99008635
4MP0003111_abnormal_nucleus_morphology3.82910320
5MP0003077_abnormal_cell_cycle3.61484516
6MP0010352_gastrointestinal_tract_polyps3.51374266
7MP0008057_abnormal_DNA_replication3.49299094
8MP0009697_abnormal_copulation2.82300987
9MP0010307_abnormal_tumor_latency2.74518978
10MP0006054_spinal_hemorrhage2.73920553
11MP0003705_abnormal_hypodermis_morpholog2.73109648
12MP0003123_paternal_imprinting2.65061662
13MP0008058_abnormal_DNA_repair2.56403577
14MP0001730_embryonic_growth_arrest2.54820735
15MP0008007_abnormal_cellular_replicative2.47916747
16MP0008932_abnormal_embryonic_tissue2.37675627
17MP0000350_abnormal_cell_proliferation2.35515854
18MP0003941_abnormal_skin_development2.34863557
19MP0002396_abnormal_hematopoietic_system2.11070450
20MP0004197_abnormal_fetal_growth/weight/1.99886878
21MP0005380_embryogenesis_phenotype1.99708203
22MP0001672_abnormal_embryogenesis/_devel1.99708203
23MP0003806_abnormal_nucleotide_metabolis1.99416777
24MP0001697_abnormal_embryo_size1.93643226
25MP0003984_embryonic_growth_retardation1.89764947
26MP0005076_abnormal_cell_differentiation1.87611919
27MP0002088_abnormal_embryonic_growth/wei1.86607170
28MP0002084_abnormal_developmental_patter1.81375409
29MP0002086_abnormal_extraembryonic_tissu1.76578226
30MP0002080_prenatal_lethality1.74226386
31MP0002085_abnormal_embryonic_tissue1.66286481
32MP0010234_abnormal_vibrissa_follicle1.55615365
33MP0000537_abnormal_urethra_morphology1.54748046
34MP0003566_abnormal_cell_adhesion1.54238742
35MP0004808_abnormal_hematopoietic_stem1.52795091
36MP0003567_abnormal_fetal_cardiomyocyte1.51683649
37MP0009053_abnormal_anal_canal1.50248325
38MP0003121_genomic_imprinting1.42045790
39MP0000490_abnormal_crypts_of1.40423847
40MP0001293_anophthalmia1.40144833
41MP0008877_abnormal_DNA_methylation1.37850166
42MP0010030_abnormal_orbit_morphology1.36350417
43MP0003950_abnormal_plasma_membrane1.35769784
44MP0003786_premature_aging1.35310417
45MP0001915_intracranial_hemorrhage1.33949829
46MP0003890_abnormal_embryonic-extraembry1.33806655
47MP0008438_abnormal_cutaneous_collagen1.31378196
48MP0006035_abnormal_mitochondrial_morpho1.30777254
49MP0009672_abnormal_birth_weight1.25517050
50MP0002009_preneoplasia1.23659781
51MP0002019_abnormal_tumor_incidence1.22075589
52MP0005023_abnormal_wound_healing1.21454540
53MP0001661_extended_life_span1.20300318
54MP0000313_abnormal_cell_death1.20088452
55MP0009703_decreased_birth_body1.15308275
56MP0003937_abnormal_limbs/digits/tail_de1.11304450
57MP0005623_abnormal_meninges_morphology1.10392281
58MP0005501_abnormal_skin_physiology1.03736139
59MP0002877_abnormal_melanocyte_morpholog1.03612516
60MP0000428_abnormal_craniofacial_morphol1.03409051
61MP0002796_impaired_skin_barrier1.01535795
62MP0000733_abnormal_muscle_development0.99633704
63MP0002111_abnormal_tail_morphology0.95158622
64MP0003186_abnormal_redox_activity0.95124265
65MP0005408_hypopigmentation0.94650299
66MP0003315_abnormal_perineum_morphology0.93899789
67MP0000703_abnormal_thymus_morphology0.90184008
68MP0002092_abnormal_eye_morphology0.89516143
69MP0006036_abnormal_mitochondrial_physio0.89294386
70MP0001849_ear_inflammation0.86923710
71MP0003718_maternal_effect0.86245089
72MP0002006_tumorigenesis0.85141200
73MP0000358_abnormal_cell_content/0.83594283
74MP0001929_abnormal_gametogenesis0.83534663
75MP0000647_abnormal_sebaceous_gland0.83306332
76MP0005384_cellular_phenotype0.82847569
77MP0005621_abnormal_cell_physiology0.82210635
78MP0003119_abnormal_digestive_system0.82181231
79MP0004782_abnormal_surfactant_physiolog0.80216680
80MP0000569_abnormal_digit_pigmentation0.79778412
81MP0003943_abnormal_hepatobiliary_system0.77417407
82MP0000372_irregular_coat_pigmentation0.76065038
83MP0002697_abnormal_eye_size0.76048008
84MP0009333_abnormal_splenocyte_physiolog0.75605959
85MP0002925_abnormal_cardiovascular_devel0.74764209
86MP0006072_abnormal_retinal_apoptosis0.74023677
87MP0005187_abnormal_penis_morphology0.72670599
88MP0002089_abnormal_postnatal_growth/wei0.71428092
89MP0004272_abnormal_basement_membrane0.71152372
90MP0000432_abnormal_head_morphology0.70869297
91MP0002210_abnormal_sex_determination0.70162276
92MP0001243_abnormal_dermal_layer0.70143276
93MP0002722_abnormal_immune_system0.70115183
94MP0003115_abnormal_respiratory_system0.69499534
95MP0003221_abnormal_cardiomyocyte_apopto0.69110657
96MP0001188_hyperpigmentation0.68427517
97MP0001545_abnormal_hematopoietic_system0.68231794
98MP0005397_hematopoietic_system_phenotyp0.68231794
99MP0005275_abnormal_skin_tensile0.67705999
100MP0001145_abnormal_male_reproductive0.67589146
101MP0000858_altered_metastatic_potential0.67544643
102MP0000653_abnormal_sex_gland0.66712961
103MP0002398_abnormal_bone_marrow0.66701838
104MP0003935_abnormal_craniofacial_develop0.66439050
105MP0000477_abnormal_intestine_morphology0.65924498
106MP0004264_abnormal_extraembryonic_tissu0.65788109
107MP0000627_abnormal_mammary_gland0.65756854
108MP0004233_abnormal_muscle_weight0.65427983
109MP0000377_abnormal_hair_follicle0.65116224
110MP0001216_abnormal_epidermal_layer0.64435871
111MP0005395_other_phenotype0.63054247
112MP0001529_abnormal_vocalization0.62918901
113MP0001286_abnormal_eye_development0.62743000
114MP0008770_decreased_survivor_rate0.62438157
115MP0001881_abnormal_mammary_gland0.62271097
116MP0003385_abnormal_body_wall0.61997038
117MP0002282_abnormal_trachea_morphology0.59857497
118MP0002160_abnormal_reproductive_system0.59715332
119MP0000689_abnormal_spleen_morphology0.59511478
120MP0004185_abnormal_adipocyte_glucose0.58145907
121MP0010678_abnormal_skin_adnexa0.57759220
122MP0000598_abnormal_liver_morphology0.57297241
123MP0002166_altered_tumor_susceptibility0.57173614
124MP0000266_abnormal_heart_morphology0.57014153
125MP0001119_abnormal_female_reproductive0.56788752
126MP0002938_white_spotting0.56380563
127MP0003755_abnormal_palate_morphology0.55926164
128MP0002060_abnormal_skin_morphology0.55137298
129MP0001853_heart_inflammation0.54546887
130MP0001177_atelectasis0.54545756
131MP0003448_altered_tumor_morphology0.54358240
132MP0000762_abnormal_tongue_morphology0.54238735
133MP0002233_abnormal_nose_morphology0.53884177
134MP0002234_abnormal_pharynx_morphology0.53638638
135MP0001727_abnormal_embryo_implantation0.53476991
136MP0003091_abnormal_cell_migration0.53465865
137MP0004084_abnormal_cardiac_muscle0.53439121
138MP0003763_abnormal_thymus_physiology0.53394330
139MP0001348_abnormal_lacrimal_gland0.53117157

Predicted human phenotypes

RankGene SetZ-score
1Agnosia (HP:0010524)4.36500464
2Ependymoma (HP:0002888)4.09245051
3Birth length less than 3rd percentile (HP:0003561)3.80611073
4Colon cancer (HP:0003003)3.70287499
5Abnormality of the preputium (HP:0100587)3.65530728
6Medulloblastoma (HP:0002885)3.54028814
7Selective tooth agenesis (HP:0001592)3.52071820
8Nephroblastoma (Wilms tumor) (HP:0002667)3.27343317
9Embryonal renal neoplasm (HP:0011794)3.14508988
10Astrocytoma (HP:0009592)3.11149485
11Abnormality of the astrocytes (HP:0100707)3.11149485
12Abnormal lung lobation (HP:0002101)3.05285979
13Abnormality of glycolysis (HP:0004366)3.03352212
14Cortical dysplasia (HP:0002539)2.99087085
15Rhabdomyosarcoma (HP:0002859)2.91682695
16Increased serum pyruvate (HP:0003542)2.85574615
17Metaphyseal dysplasia (HP:0100255)2.85297346
18Deviation of the thumb (HP:0009603)2.77091571
19Abnormality of methionine metabolism (HP:0010901)2.75909088
20Abnormality of the duodenum (HP:0002246)2.75005303
21Absent frontal sinuses (HP:0002688)2.74951557
22Degeneration of anterior horn cells (HP:0002398)2.74444195
23Abnormality of the anterior horn cell (HP:0006802)2.74444195
24Syringomyelia (HP:0003396)2.73508042
25Spinal cord lesions (HP:0100561)2.73508042
26Biliary tract neoplasm (HP:0100574)2.71491595
27Glioma (HP:0009733)2.68838440
28Chromsome breakage (HP:0040012)2.67970436
29Microvesicular hepatic steatosis (HP:0001414)2.67428159
30Proximal placement of thumb (HP:0009623)2.63420682
31Abnormality of the labia minora (HP:0012880)2.62425113
32Abnormality of chromosome stability (HP:0003220)2.60911016
33Reticulocytopenia (HP:0001896)2.58108959
34Progressive external ophthalmoplegia (HP:0000590)2.57945746
35Breast hypoplasia (HP:0003187)2.54231634
36Short 4th metacarpal (HP:0010044)2.44736023
37Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)2.44736023
38Missing ribs (HP:0000921)2.42160234
39Abnormality of the carotid arteries (HP:0005344)2.41720943
40Basal cell carcinoma (HP:0002671)2.37844339
41Increased nuchal translucency (HP:0010880)2.37603295
42Spastic diplegia (HP:0001264)2.36905762
43Neoplasm of the oral cavity (HP:0100649)2.36694313
44Atrophy/Degeneration involving motor neurons (HP:0007373)2.35705859
45Short middle phalanx of the 5th finger (HP:0004220)2.35078112
46Volvulus (HP:0002580)2.32836657
47Abnormality of the umbilical cord (HP:0010881)2.31666874
48Abnormality of cells of the erythroid lineage (HP:0012130)2.29333558
49Neoplasm of the pancreas (HP:0002894)2.25674160
50Abnormal umbilical cord blood vessels (HP:0011403)2.24726097
51Single umbilical artery (HP:0001195)2.24726097
52Abnormality of the fetal cardiovascular system (HP:0010948)2.24726097
53Amaurosis fugax (HP:0100576)2.23728506
54Abnormality of the calcaneus (HP:0008364)2.23373548
55Cutaneous melanoma (HP:0012056)2.22678055
56Chromosomal breakage induced by crosslinking agents (HP:0003221)2.22224726
57Pelvic girdle muscle weakness (HP:0003749)2.22079794
58Ankle contracture (HP:0006466)2.20332078
59Neoplasm of striated muscle (HP:0009728)2.18586866
60Acute myeloid leukemia (HP:0004808)2.18038177
61Supernumerary bones of the axial skeleton (HP:0009144)2.14757065
62Malignant gastrointestinal tract tumors (HP:0006749)2.13295708
63Gastrointestinal carcinoma (HP:0002672)2.13295708
64Supernumerary ribs (HP:0005815)2.12666322
65Protrusio acetabuli (HP:0003179)2.12645857
66Impulsivity (HP:0100710)2.11587542
67Abnormal number of erythroid precursors (HP:0012131)2.09042274
68Deep philtrum (HP:0002002)2.08809673
69Increased density of long bones (HP:0006392)2.07845312
70Oral leukoplakia (HP:0002745)2.07496226
71Patellar aplasia (HP:0006443)2.07178344
72Microglossia (HP:0000171)2.06919049
73Clubbing of toes (HP:0100760)2.06664298
74High pitched voice (HP:0001620)2.06076940
7511 pairs of ribs (HP:0000878)2.05578410
76Myelodysplasia (HP:0002863)2.04863259
77Multiple enchondromatosis (HP:0005701)2.04840565
78Abnormalities of placenta or umbilical cord (HP:0001194)2.02650035
79Ovarian neoplasm (HP:0100615)2.02008815
80Aplasia/Hypoplasia of the frontal sinuses (HP:0009119)2.01815494
81Neoplasm of the rectum (HP:0100743)2.01784833
82Atresia of the external auditory canal (HP:0000413)2.00230552
83Progressive muscle weakness (HP:0003323)1.99720391
84Neoplasm of the colon (HP:0100273)1.99122638
85Postnatal microcephaly (HP:0005484)1.98996633
86Absent radius (HP:0003974)1.98689870
87Choanal atresia (HP:0000453)1.98209533
88Pancreatic islet-cell hyperplasia (HP:0004510)1.96955455
89Abnormality of pyruvate family amino acid metabolism (HP:0010915)1.96855724
90Abnormality of alanine metabolism (HP:0010916)1.96855724
91Hyperalaninemia (HP:0003348)1.96855724
92Horseshoe kidney (HP:0000085)1.96371261
93Abnormality of pyrimidine metabolism (HP:0004353)1.95029391
94Meckel diverticulum (HP:0002245)1.94977095
95Aplasia/hypoplasia of the humerus (HP:0006507)1.94398065
96Angiofibromas (HP:0010615)1.93664879
97Adenoma sebaceum (HP:0009720)1.93664879
98Amyotrophic lateral sclerosis (HP:0007354)1.93267338
99Squamous cell carcinoma (HP:0002860)1.92929270
100Aplasia/Hypoplasia of the patella (HP:0006498)1.92136063
101Embryonal neoplasm (HP:0002898)1.91339597
102Neoplasm of the small intestine (HP:0100833)1.90982519
103Shoulder girdle muscle weakness (HP:0003547)1.90594362
104Reduced antithrombin III activity (HP:0001976)1.88937767
105Abnormality of the peritoneum (HP:0002585)1.88911738
106Freckling (HP:0001480)1.88137645
107Arteriovenous malformation (HP:0100026)1.87547882
108Abnormal number of incisors (HP:0011064)1.87377803
109Secondary amenorrhea (HP:0000869)1.87062113
110Cafe-au-lait spot (HP:0000957)1.86990045
111Carpal bone hypoplasia (HP:0001498)1.86066136
112Sloping forehead (HP:0000340)1.85291111
113Intestinal polyp (HP:0005266)1.85140609
114Intestinal polyposis (HP:0200008)1.84867506
115Abnormality of aspartate family amino acid metabolism (HP:0010899)1.84484197
116Short humerus (HP:0005792)1.82825874
117Absent forearm bone (HP:0003953)1.80777220
118Aplasia involving forearm bones (HP:0009822)1.80777220
119Aplastic anemia (HP:0001915)1.79988084
120Abnormality of the ileum (HP:0001549)1.79676547
121Short 5th finger (HP:0009237)1.79648544
122Prominent nose (HP:0000448)1.79394869
123Overlapping toe (HP:0001845)1.78141982
124Triphalangeal thumb (HP:0001199)1.78122601
125Abnormality of serum amino acid levels (HP:0003112)1.77767018
126Duodenal stenosis (HP:0100867)1.77387893
127Small intestinal stenosis (HP:0012848)1.77387893
128Uterine neoplasm (HP:0010784)1.77208265
129Sensory axonal neuropathy (HP:0003390)1.76961122
130Breast carcinoma (HP:0003002)1.76956508
131Ectopic kidney (HP:0000086)1.76542676
132Wrist flexion contracture (HP:0001239)1.76467223
133Abnormality of the musculature of the pelvis (HP:0001469)1.76284601
134Abnormality of the hip-girdle musculature (HP:0001445)1.76284601
135Glossoptosis (HP:0000162)1.76033885
136Heterotopia (HP:0002282)1.75417048
137Neuroblastoma (HP:0003006)1.74894952
138Primitive neuroectodermal tumor (HP:0030065)1.74894952
139Neuroblastic tumors (HP:0004376)1.74894952
140Peripheral primitive neuroectodermal neoplasm (HP:0030067)1.74894952
141Aplasia/Hypoplasia of the uvula (HP:0010293)1.74876505
142Premature ovarian failure (HP:0008209)1.73366621
143Abnormality of the 4th metacarpal (HP:0010012)1.71312340
144Slender long bone (HP:0003100)1.70088123
145Abnormal biliary tract morphology (HP:0012440)1.69922454
146Megaloblastic anemia (HP:0001889)1.69322894
147Insidious onset (HP:0003587)1.68494920
148Termporal pattern (HP:0011008)1.68494920
149Increased serum lactate (HP:0002151)1.68309728
150Abnormal auditory evoked potentials (HP:0006958)1.67675949
151Bone marrow hypocellularity (HP:0005528)1.66088029
152Abnormality of placental membranes (HP:0011409)1.62112961
153Amniotic constriction ring (HP:0009775)1.62112961
154Neuroepithelial neoplasm (HP:0030063)1.61897176

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CDC74.26172427
2WEE13.86012218
3BUB13.34899474
4PBK2.99002511
5NEK12.67078101
6EIF2AK12.60877104
7TSSK62.53151604
8NEK22.50506434
9PKN22.49424360
10SCYL22.44285602
11EEF2K2.37811666
12TTK2.29562521
13SRPK12.27812024
14CDK122.15204850
15PASK2.01904715
16BRSK21.97114197
17RPS6KB21.95881160
18MKNK11.95409398
19FLT31.90801912
20EPHA21.90701771
21MAP3K81.90100212
22TRIM281.84198630
23PLK31.78498921
24PLK11.68676791
25ATR1.67172259
26EIF2AK31.60955534
27ACVR1B1.57672217
28STK101.57155537
29AURKB1.56179012
30TAF11.55370357
31VRK21.46607147
32ALK1.36519558
33CDK41.32501102
34RPS6KA41.30504258
35CHEK11.30178275
36TGFBR11.26634005
37CDK71.26026269
38TLK11.24494122
39LATS11.21950619
40TTN1.21262614
41TESK21.19326584
42LRRK21.17418742
43PAK41.14619191
44PLK41.13729789
45CDK61.13435523
46MKNK21.12173597
47CHEK21.08502798
48ZAK1.06773993
49TRIB31.05705847
50NUAK11.05670082
51BCR1.03856450
52STK31.03238345
53MAP3K101.02950758
54ATM1.01476818
55BRD40.99225615
56MST1R0.98116612
57BRSK10.96167971
58NME20.94937247
59FGFR10.93897334
60VRK10.91772758
61CDK20.91734195
62JAK30.90121613
63STK160.89924953
64CLK10.88921317
65AURKA0.84567149
66PDK30.83614990
67PDK40.83614990
68DYRK30.82546327
69PDGFRA0.79034306
70PIM10.78773290
71MTOR0.78737563
72PNCK0.78146782
73SMG10.78060089
74MET0.77975877
75PAK20.77322953
76NME10.76769022
77TESK10.74242529
78STK40.73166351
79BRAF0.72507376
80CDK10.69488862
81MELK0.67593426
82CSNK2A20.66392682
83PTK60.61663825
84NEK90.61203166
85PLK20.59908155
86CSNK1D0.55679798
87CSNK1E0.54153821
88LATS20.53839626
89SIK30.53547034
90TNIK0.53411495
91CDK80.52763273
92CSNK1G10.51874921
93RPS6KB10.50732459
94PRKDC0.47921769
95CSNK1A1L0.43935964
96CDK90.43561708
97AKT20.43294820
98MAP3K120.42958173
99CSNK1G30.42182402
100CSNK2A10.41998008
101RAF10.40521175
102ERBB30.39780460
103MST40.39771493
104PAK10.39710504
105PRKCI0.39358694
106MAP2K30.38703034
107STK390.38079200
108GRK60.37489479
109PDK20.36060258
110BMX0.35903263
111BMPR1B0.35502814
112RPS6KA50.35369950
113MAPK140.34083493
114WNK30.32643059
115DDR20.29723879
116STK240.29256670
117DAPK10.29055535
118BMPR20.27877306
119CDK30.26548940
120ILK0.26179561
121MAPK10.25230114
122FGFR30.24450480
123KSR10.24206549
124LIMK10.24195964
125CDK180.23886500
126MAPKAPK30.23341425
127STK38L0.23233908
128AKT10.22325335
129EIF2AK20.22033325
130ERBB40.21516465
131CCNB10.20966135

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030304.44355262
2Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030083.98555635
3Mismatch repair_Homo sapiens_hsa034303.84300248
4RNA transport_Homo sapiens_hsa030133.52119417
5One carbon pool by folate_Homo sapiens_hsa006703.47149692
6Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009703.25339080
7Spliceosome_Homo sapiens_hsa030403.14227899
8Cell cycle_Homo sapiens_hsa041102.80608593
9Nucleotide excision repair_Homo sapiens_hsa034202.64672470
10Base excision repair_Homo sapiens_hsa034102.47158222
11Homologous recombination_Homo sapiens_hsa034402.23786411
12RNA polymerase_Homo sapiens_hsa030202.22684216
13Systemic lupus erythematosus_Homo sapiens_hsa053222.08800507
14mRNA surveillance pathway_Homo sapiens_hsa030152.06294320
15Protein export_Homo sapiens_hsa030602.05419273
16Proteasome_Homo sapiens_hsa030502.04532570
17Ribosome_Homo sapiens_hsa030102.02656437
18Non-homologous end-joining_Homo sapiens_hsa034501.99858288
19RNA degradation_Homo sapiens_hsa030181.96701880
20Pyrimidine metabolism_Homo sapiens_hsa002401.83511695
21Fanconi anemia pathway_Homo sapiens_hsa034601.78976977
22p53 signaling pathway_Homo sapiens_hsa041151.68768480
23Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.61536085
24Viral carcinogenesis_Homo sapiens_hsa052031.55606823
25Pyruvate metabolism_Homo sapiens_hsa006201.38977795
26Selenocompound metabolism_Homo sapiens_hsa004501.33535926
27Propanoate metabolism_Homo sapiens_hsa006401.32977466
28Biosynthesis of amino acids_Homo sapiens_hsa012301.32902492
29Basal transcription factors_Homo sapiens_hsa030221.31032453
30Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.28764104
31Antigen processing and presentation_Homo sapiens_hsa046121.21187611
32Epstein-Barr virus infection_Homo sapiens_hsa051691.18578469
33Progesterone-mediated oocyte maturation_Homo sapiens_hsa049141.17973895
34Steroid biosynthesis_Homo sapiens_hsa001001.15572019
35Oocyte meiosis_Homo sapiens_hsa041141.15035754
36MicroRNAs in cancer_Homo sapiens_hsa052061.07671522
37Cyanoamino acid metabolism_Homo sapiens_hsa004600.99003582
38HTLV-I infection_Homo sapiens_hsa051660.98535278
39Cysteine and methionine metabolism_Homo sapiens_hsa002700.96350329
40Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.94398974
41Small cell lung cancer_Homo sapiens_hsa052220.92252462
42Herpes simplex infection_Homo sapiens_hsa051680.90577550
432-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.89696371
44Purine metabolism_Homo sapiens_hsa002300.88431617
45Thyroid cancer_Homo sapiens_hsa052160.85620630
46Pentose phosphate pathway_Homo sapiens_hsa000300.85472366
47Drug metabolism - other enzymes_Homo sapiens_hsa009830.85119660
48Fatty acid elongation_Homo sapiens_hsa000620.84243775
49Carbon metabolism_Homo sapiens_hsa012000.82286799
50Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.78868981
51Alcoholism_Homo sapiens_hsa050340.78638946
52Central carbon metabolism in cancer_Homo sapiens_hsa052300.78626749
53Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.76107550
54Adherens junction_Homo sapiens_hsa045200.69746225
55mTOR signaling pathway_Homo sapiens_hsa041500.69535919
56Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.68123066
57Hippo signaling pathway_Homo sapiens_hsa043900.67735076
58Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.67380666
59Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.66007786
60TGF-beta signaling pathway_Homo sapiens_hsa043500.65923543
61Legionellosis_Homo sapiens_hsa051340.65528421
62Chronic myeloid leukemia_Homo sapiens_hsa052200.62741873
63Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.62672430
64Transcriptional misregulation in cancer_Homo sapiens_hsa052020.60720387
65Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.59962146
66Colorectal cancer_Homo sapiens_hsa052100.59851739
67Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.58659453
68Bladder cancer_Homo sapiens_hsa052190.56906916
69Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.56694230
70Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.56644635
71Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.51779754
72HIF-1 signaling pathway_Homo sapiens_hsa040660.50856679
73Proteoglycans in cancer_Homo sapiens_hsa052050.50463189
74Apoptosis_Homo sapiens_hsa042100.49992251
75Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.49666780
76Viral myocarditis_Homo sapiens_hsa054160.49504243
77Hepatitis B_Homo sapiens_hsa051610.45693300
78Vitamin B6 metabolism_Homo sapiens_hsa007500.45223193
79Lysine degradation_Homo sapiens_hsa003100.45028127
80Basal cell carcinoma_Homo sapiens_hsa052170.44050571
81Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.40993000
82Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.39805052
83N-Glycan biosynthesis_Homo sapiens_hsa005100.38390701
84Sulfur metabolism_Homo sapiens_hsa009200.37430262
85Notch signaling pathway_Homo sapiens_hsa043300.36733946
86Metabolic pathways_Homo sapiens_hsa011000.34720696
87Measles_Homo sapiens_hsa051620.34259568
88Prostate cancer_Homo sapiens_hsa052150.34078789
89Focal adhesion_Homo sapiens_hsa045100.33195499
90Pathways in cancer_Homo sapiens_hsa052000.32959800
91Shigellosis_Homo sapiens_hsa051310.32310136
92Huntingtons disease_Homo sapiens_hsa050160.31025764
93Fatty acid metabolism_Homo sapiens_hsa012120.30116162
94Renin-angiotensin system_Homo sapiens_hsa046140.29852170
95Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.29214818
96PI3K-Akt signaling pathway_Homo sapiens_hsa041510.27770573
97Tight junction_Homo sapiens_hsa045300.27636767
98Pancreatic cancer_Homo sapiens_hsa052120.27364774
99Parkinsons disease_Homo sapiens_hsa050120.27213199
100NF-kappa B signaling pathway_Homo sapiens_hsa040640.26894292
101Influenza A_Homo sapiens_hsa051640.25941048
102Leukocyte transendothelial migration_Homo sapiens_hsa046700.24980053
103Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.24678989
104ECM-receptor interaction_Homo sapiens_hsa045120.23813468
105Non-small cell lung cancer_Homo sapiens_hsa052230.23234127
106Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.22983351
107Endometrial cancer_Homo sapiens_hsa052130.22661287
108Folate biosynthesis_Homo sapiens_hsa007900.21289146
109Arginine and proline metabolism_Homo sapiens_hsa003300.20494226
110Glutathione metabolism_Homo sapiens_hsa004800.20403052
111Neurotrophin signaling pathway_Homo sapiens_hsa047220.18231826
112Nitrogen metabolism_Homo sapiens_hsa009100.17616050
113FoxO signaling pathway_Homo sapiens_hsa040680.15657387
114Melanoma_Homo sapiens_hsa052180.15499774
115Acute myeloid leukemia_Homo sapiens_hsa052210.15464216
116Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.15433328
117Sulfur relay system_Homo sapiens_hsa041220.15168061
118Hedgehog signaling pathway_Homo sapiens_hsa043400.13979167
119Wnt signaling pathway_Homo sapiens_hsa043100.13788050
120Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.10741580
121Pentose and glucuronate interconversions_Homo sapiens_hsa000400.04467762
122Fructose and mannose metabolism_Homo sapiens_hsa000510.04245635
123Galactose metabolism_Homo sapiens_hsa000520.03132122

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