ABCF1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the GCN20 subfamily. Unlike other members of the superfamily, this protein lacks the transmembrane domains which are characteristic of most ABC transporters. This protein may be regulated by tumor necrosis factor-alpha and play a role in enhancement of protein synthesis and the inflammation process. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1establishment of integrated proviral latency (GO:0075713)4.72626161
2DNA unwinding involved in DNA replication (GO:0006268)4.69713535
3protein localization to kinetochore (GO:0034501)4.44660023
4maturation of SSU-rRNA (GO:0030490)4.43197862
5formation of translation preinitiation complex (GO:0001731)4.25599800
6IMP biosynthetic process (GO:0006188)4.18555907
7heterochromatin organization (GO:0070828)4.18404091
8folic acid-containing compound biosynthetic process (GO:0009396)4.17175380
9nucleobase biosynthetic process (GO:0046112)4.07164276
10viral transcription (GO:0019083)4.03162651
11ribosomal large subunit biogenesis (GO:0042273)3.98411850
12translational termination (GO:0006415)3.92836160
13protein localization to chromosome, centromeric region (GO:0071459)3.89031256
14mitotic nuclear envelope disassembly (GO:0007077)3.85930883
15nuclear pore organization (GO:0006999)3.82882248
16ribosomal small subunit assembly (GO:0000028)3.80297373
17DNA strand elongation involved in DNA replication (GO:0006271)3.76934116
18* translational initiation (GO:0006413)3.73967941
19DNA replication initiation (GO:0006270)3.71440237
20ribosomal small subunit biogenesis (GO:0042274)3.68528493
21nuclear pore complex assembly (GO:0051292)3.67839331
22regulation of translational termination (GO:0006449)3.66954208
23ribosome assembly (GO:0042255)3.66381016
24IMP metabolic process (GO:0046040)3.64280018
25translational elongation (GO:0006414)3.64173996
26establishment of viral latency (GO:0019043)3.63281757
27regulation of translational fidelity (GO:0006450)3.62093751
28DNA strand elongation (GO:0022616)3.58425020
29mitotic metaphase plate congression (GO:0007080)3.58005170
30nuclear envelope disassembly (GO:0051081)3.56276590
31membrane disassembly (GO:0030397)3.56276590
32purine nucleobase biosynthetic process (GO:0009113)3.54026846
33nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)3.53939033
34* ribonucleoprotein complex biogenesis (GO:0022613)3.49146324
35regulation of gene silencing by RNA (GO:0060966)3.49060513
36regulation of posttranscriptional gene silencing (GO:0060147)3.49060513
37regulation of gene silencing by miRNA (GO:0060964)3.49060513
38mitotic sister chromatid segregation (GO:0000070)3.48011022
39protein complex localization (GO:0031503)3.47594630
40DNA topological change (GO:0006265)3.46377542
41regulation of attachment of spindle microtubules to kinetochore (GO:0051988)3.46078474
42mitotic sister chromatid cohesion (GO:0007064)3.43865957
43DNA replication-dependent nucleosome assembly (GO:0006335)3.42141568
44DNA replication-dependent nucleosome organization (GO:0034723)3.42141568
45DNA replication checkpoint (GO:0000076)3.37454186
46chromatin remodeling at centromere (GO:0031055)3.37048568
47CENP-A containing nucleosome assembly (GO:0034080)3.31692180
48* ribosome biogenesis (GO:0042254)3.31367130
49DNA duplex unwinding (GO:0032508)3.28433269
50rRNA processing (GO:0006364)3.28321919
51DNA geometric change (GO:0032392)3.25873529
52regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.25660773
53pre-miRNA processing (GO:0031054)3.25370069
54sister chromatid segregation (GO:0000819)3.23176907
55regulation of spindle organization (GO:0090224)3.21883557
56rRNA modification (GO:0000154)3.21483698
57chromosome condensation (GO:0030261)3.20303445
58negative regulation of mRNA metabolic process (GO:1903312)3.20110179
59rRNA metabolic process (GO:0016072)3.20017472
60mitotic chromosome condensation (GO:0007076)3.18777047
61telomere maintenance via semi-conservative replication (GO:0032201)3.12971385
62spliceosomal tri-snRNP complex assembly (GO:0000244)3.12619797
63DNA replication-independent nucleosome organization (GO:0034724)3.12396249
64DNA replication-independent nucleosome assembly (GO:0006336)3.12396249
65maturation of 5.8S rRNA (GO:0000460)3.12276087
66cellular protein complex disassembly (GO:0043624)3.11821661
67SRP-dependent cotranslational protein targeting to membrane (GO:0006614)3.11321556
68DNA deamination (GO:0045006)3.10989255
69negative regulation of mRNA splicing, via spliceosome (GO:0048025)3.10911542
70dosage compensation (GO:0007549)3.10579865
71positive regulation of chromosome segregation (GO:0051984)3.07910440
72spliceosomal snRNP assembly (GO:0000387)3.04978654
73protein complex disassembly (GO:0043241)3.04778715
74viral life cycle (GO:0019058)3.04356860
75cellular protein complex localization (GO:0034629)3.04004220
76pseudouridine synthesis (GO:0001522)3.03470145
77protein targeting to ER (GO:0045047)3.03467083
78chromatin assembly (GO:0031497)3.02800336
79regulation of helicase activity (GO:0051095)3.01341810
80mitochondrial ATP synthesis coupled proton transport (GO:0042776)3.00615791
81protein localization to chromosome (GO:0034502)2.99767780
82cotranslational protein targeting to membrane (GO:0006613)2.99381224
83metaphase plate congression (GO:0051310)2.99212388
84tRNA aminoacylation for protein translation (GO:0006418)2.98661968
85transcription from mitochondrial promoter (GO:0006390)2.98228840
86regulation of histone H3-K9 methylation (GO:0051570)2.97748382
87regulation of mitotic spindle organization (GO:0060236)2.96434337
88viral mRNA export from host cell nucleus (GO:0046784)2.96248253
89chromosome segregation (GO:0007059)2.96136686
90negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)2.95866294
91establishment of protein localization to mitochondrial membrane (GO:0090151)2.95186051
92amino acid activation (GO:0043038)2.94934257
93tRNA aminoacylation (GO:0043039)2.94934257
94* cellular component biogenesis (GO:0044085)2.90719817
95anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:02.90488486
96establishment of protein localization to endoplasmic reticulum (GO:0072599)2.89738123
97* translation (GO:0006412)2.89277524
98rRNA methylation (GO:0031167)2.88755832
99negative regulation of histone methylation (GO:0031061)2.88605916
100ATP-dependent chromatin remodeling (GO:0043044)2.87918075
101negative regulation of chromosome segregation (GO:0051985)2.87249147
102negative regulation of RNA splicing (GO:0033119)2.87001210
103RNA splicing, via transesterification reactions (GO:0000375)2.85248975
104mRNA splicing, via spliceosome (GO:0000398)2.84140931
105RNA splicing, via transesterification reactions with bulged adenosine as nucleophile (GO:0000377)2.84140931
106regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)2.84107783
107nuclear envelope organization (GO:0006998)2.84107402
108L-serine metabolic process (GO:0006563)2.82941522
109macromolecular complex disassembly (GO:0032984)2.82022195
110pore complex assembly (GO:0046931)2.79548786
111protein localization to endoplasmic reticulum (GO:0070972)2.77725548
112telomere maintenance via recombination (GO:0000722)2.76470889
113telomere maintenance via telomere lengthening (GO:0010833)2.75879678
114mRNA stabilization (GO:0048255)2.74433470
115RNA stabilization (GO:0043489)2.74433470
116chromatin assembly or disassembly (GO:0006333)2.72781328
117positive regulation of histone H3-K4 methylation (GO:0051571)2.72723155
118DNA conformation change (GO:0071103)2.72666664
119nuclear-transcribed mRNA catabolic process (GO:0000956)2.72584517
120mitotic recombination (GO:0006312)2.71024475
121peptidyl-arginine omega-N-methylation (GO:0035247)2.68338476
122RNA catabolic process (GO:0006401)2.65929023
123paraxial mesoderm development (GO:0048339)2.65558962
124regulation of RNA export from nucleus (GO:0046831)2.64523690
125trophectodermal cell differentiation (GO:0001829)2.63430750
126kinetochore organization (GO:0051383)2.63299443
127negative regulation of mRNA processing (GO:0050686)2.62234641
128chaperone-mediated protein complex assembly (GO:0051131)2.61912004
129establishment of chromosome localization (GO:0051303)2.60764248
1303-UTR-mediated mRNA stabilization (GO:0070935)2.60581225
131folic acid metabolic process (GO:0046655)2.60377744
132negative regulation of translational initiation (GO:0045947)2.59851180

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human7.46349403
2FOXM1_23109430_ChIP-Seq_U2OS_Human3.98087166
3MYC_18555785_ChIP-Seq_MESCs_Mouse3.80455097
4* EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.62871381
5MYC_19079543_ChIP-ChIP_MESCs_Mouse2.84969173
6E2F4_17652178_ChIP-ChIP_JURKAT_Human2.84230024
7FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.75427316
8EGR1_19374776_ChIP-ChIP_THP-1_Human2.50387627
9MYC_19030024_ChIP-ChIP_MESCs_Mouse2.43278287
10MYC_22102868_ChIP-Seq_BL_Human2.38503194
11MYC_18358816_ChIP-ChIP_MESCs_Mouse2.37400996
12ETS1_20019798_ChIP-Seq_JURKAT_Human2.29936350
13EST1_17652178_ChIP-ChIP_JURKAT_Human2.13816226
14XRN2_22483619_ChIP-Seq_HELA_Human2.12385488
15CREB1_15753290_ChIP-ChIP_HEK293T_Human2.10756272
16* NELFA_20434984_ChIP-Seq_ESCs_Mouse2.04699989
17JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.93941503
18MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.90821454
19AR_21909140_ChIP-Seq_LNCAP_Human1.85589515
20KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.85060408
21VDR_21846776_ChIP-Seq_THP-1_Human1.69476903
22GABP_17652178_ChIP-ChIP_JURKAT_Human1.69172055
23CIITA_25753668_ChIP-Seq_RAJI_Human1.67434920
24STAT3_1855785_ChIP-Seq_MESCs_Mouse1.67161538
25HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.61306919
26SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.60392870
27* MYCN_18555785_ChIP-Seq_MESCs_Mouse1.60153684
28E2F1_21310950_ChIP-Seq_MCF-7_Human1.59190886
29NANOG_18555785_ChIP-Seq_MESCs_Mouse1.58843265
30POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.56913556
31VDR_23849224_ChIP-Seq_CD4+_Human1.55242427
32POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.54783694
33* E2F1_18555785_ChIP-Seq_MESCs_Mouse1.54763955
34MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.53006763
35KDM5A_27292631_Chip-Seq_BREAST_Human1.52321648
36CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.52143915
37DCP1A_22483619_ChIP-Seq_HELA_Human1.51936694
38KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.50224060
39TTF2_22483619_ChIP-Seq_HELA_Human1.49622208
40* GABP_19822575_ChIP-Seq_HepG2_Human1.49180974
41NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.47558783
42FOXP3_21729870_ChIP-Seq_TREG_Human1.47454800
43TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.46646977
44NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.44652373
45TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.43845203
46PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.43163072
47CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.39931160
48ZFX_18555785_ChIP-Seq_MESCs_Mouse1.39751587
49KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.36720409
50THAP11_20581084_ChIP-Seq_MESCs_Mouse1.35353650
51SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.34704355
52DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.32532107
53KLF4_18555785_ChIP-Seq_MESCs_Mouse1.31706145
54MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.30926287
55YY1_21170310_ChIP-Seq_MESCs_Mouse1.28844497
56ZNF263_19887448_ChIP-Seq_K562_Human1.28017432
57SRF_21415370_ChIP-Seq_HL-1_Mouse1.26543926
58TP63_19390658_ChIP-ChIP_HaCaT_Human1.25798787
59TP63_17297297_ChIP-ChIP_HaCaT_Human1.25407481
60KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.25068012
61KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.25068012
62KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.25068012
63ELF1_17652178_ChIP-ChIP_JURKAT_Human1.23133855
64STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.22516485
65CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.19997208
66PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.19939323
67PADI4_21655091_ChIP-ChIP_MCF-7_Human1.19682106
68ESR1_15608294_ChIP-ChIP_MCF-7_Human1.19644290
69YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.17895988
70ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.17213010
71ATF3_27146783_Chip-Seq_COLON_Human1.14643639
72ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.13079657
73TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.11157960
74ERG_20887958_ChIP-Seq_HPC-7_Mouse1.09535919
75ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.07716197
76CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.07611775
77BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.07298372
78SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.07297752
79ELK3_25401928_ChIP-Seq_HUVEC_Human1.07139824
80POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.06890036
81TFEB_21752829_ChIP-Seq_HELA_Human1.04031165
82DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.03532830
83ELK1_19687146_ChIP-ChIP_HELA_Human1.03360830
84KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.02557483
85SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.02324030
86SREBP1_19666523_ChIP-Seq_LIVER_Mouse1.01724131
87CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.01574093
88TCF3_18692474_ChIP-Seq_MEFs_Mouse1.00988144
89OCT4_18692474_ChIP-Seq_MEFs_Mouse1.00842589
90SOX2_18555785_ChIP-Seq_MESCs_Mouse1.00155756
91CNOT3_19339689_ChIP-ChIP_MESCs_Mouse1.00087612
92STAT6_21828071_ChIP-Seq_BEAS2B_Human0.99106789
93KDM2B_26808549_Chip-Seq_SIL-ALL_Human0.98854231
94UTX_26944678_Chip-Seq_JUKART_Human0.98831746
95E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human0.98040853
96NR0B1_18358816_ChIP-ChIP_MESCs_Mouse0.97233794
97SIN3A_21632747_ChIP-Seq_MESCs_Mouse0.95669659
98HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.95435351
99CHD1_26751641_Chip-Seq_LNCaP_Human0.95337758
100PPARG_19300518_ChIP-PET_3T3-L1_Mouse0.94741274
101TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse0.94726479
102NANOG_21062744_ChIP-ChIP_HESCs_Human0.94192919
103E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse0.93759183
104* PRDM5_23873026_ChIP-Seq_MEFs_Mouse0.93647625
105* CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse0.93123606
106TCF7_22412390_ChIP-Seq_EML_Mouse0.92779118
107MAF_26560356_Chip-Seq_TH1_Human0.91510604
108NOTCH1_21737748_ChIP-Seq_TLL_Human0.91402423
109FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse0.91268848
110HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human0.91259033
111HOXB4_20404135_ChIP-ChIP_EML_Mouse0.90909246
112SOX2_18692474_ChIP-Seq_MEFs_Mouse0.89913944
113* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.89290280
114SOX17_20123909_ChIP-Seq_XEN_Mouse0.87509983
115* CEBPB_24764292_ChIP-Seq_MC3T3_Mouse0.87506730
116KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human0.86702579
117NCOR1_26117541_ChIP-Seq_K562_Human0.85962300
118ASH2L_23239880_ChIP-Seq_MESCs_Mouse0.85934145
119* TBX5_21415370_ChIP-Seq_HL-1_Mouse0.85174905
120* MYC_18940864_ChIP-ChIP_HL60_Human0.85085812

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching4.41046986
2MP0003111_abnormal_nucleus_morphology3.74423243
3MP0004957_abnormal_blastocyst_morpholog3.72948748
4MP0003077_abnormal_cell_cycle3.22428429
5MP0010094_abnormal_chromosome_stability3.16430033
6MP0008057_abnormal_DNA_replication3.04799301
7MP0010352_gastrointestinal_tract_polyps2.78164857
8MP0003705_abnormal_hypodermis_morpholog2.55860863
9MP0001730_embryonic_growth_arrest2.50068584
10MP0000350_abnormal_cell_proliferation2.16764904
11MP0003941_abnormal_skin_development2.09942118
12MP0005076_abnormal_cell_differentiation2.07447617
13MP0008007_abnormal_cellular_replicative2.05161140
14MP0008932_abnormal_embryonic_tissue1.95383735
15MP0003123_paternal_imprinting1.93615244
16MP0010307_abnormal_tumor_latency1.88118202
17MP0001672_abnormal_embryogenesis/_devel1.84273187
18MP0005380_embryogenesis_phenotype1.84273187
19MP0003566_abnormal_cell_adhesion1.83796391
20MP0008058_abnormal_DNA_repair1.79909926
21MP0001697_abnormal_embryo_size1.74514310
22MP0003984_embryonic_growth_retardation1.73902460
23MP0002396_abnormal_hematopoietic_system1.73857840
24MP0001849_ear_inflammation1.72331424
25MP0002088_abnormal_embryonic_growth/wei1.71648010
26MP0006292_abnormal_olfactory_placode1.67868896
27MP0004197_abnormal_fetal_growth/weight/1.62197956
28MP0000490_abnormal_crypts_of1.61207389
29MP0002080_prenatal_lethality1.60011368
30MP0002085_abnormal_embryonic_tissue1.59396149
31MP0002254_reproductive_system_inflammat1.55241881
32MP0002086_abnormal_extraembryonic_tissu1.54044530
33MP0002084_abnormal_developmental_patter1.53550278
34MP0000750_abnormal_muscle_regeneration1.50254642
35MP0008877_abnormal_DNA_methylation1.48801435
36MP0003300_gastrointestinal_ulcer1.48391791
37MP0009379_abnormal_foot_pigmentation1.44388551
38MP0003567_abnormal_fetal_cardiomyocyte1.42907823
39MP0002938_white_spotting1.39949288
40MP0004185_abnormal_adipocyte_glucose1.38166147
41MP0003806_abnormal_nucleotide_metabolis1.33210270
42MP0004233_abnormal_muscle_weight1.30808786
43MP0004808_abnormal_hematopoietic_stem1.28713770
44MP0009840_abnormal_foam_cell1.28584455
45MP0000313_abnormal_cell_death1.27896555
46MP0009278_abnormal_bone_marrow1.27178061
47MP0004264_abnormal_extraembryonic_tissu1.25886281
48MP0000537_abnormal_urethra_morphology1.25778637
49MP0002019_abnormal_tumor_incidence1.22533441
50MP0000733_abnormal_muscle_development1.20900026
51MP0001346_abnormal_lacrimal_gland1.20576549
52MP0003890_abnormal_embryonic-extraembry1.19332123
53MP0005408_hypopigmentation1.18351208
54MP0003786_premature_aging1.16070478
55MP0003221_abnormal_cardiomyocyte_apopto1.15266297
56MP0009053_abnormal_anal_canal1.15231107
57MP0005501_abnormal_skin_physiology1.14433108
58MP0006035_abnormal_mitochondrial_morpho1.13103972
59MP0003186_abnormal_redox_activity1.12659677
60MP0003763_abnormal_thymus_physiology1.11778484
61MP0010030_abnormal_orbit_morphology1.10665102
62MP0003119_abnormal_digestive_system1.09167115
63MP0002089_abnormal_postnatal_growth/wei1.08405793
64MP0005023_abnormal_wound_healing1.06422051
65MP0009333_abnormal_splenocyte_physiolog1.04218327
66MP0003718_maternal_effect1.01708484
67MP0000703_abnormal_thymus_morphology0.97477446
68MP0003878_abnormal_ear_physiology0.96087659
69MP0005377_hearing/vestibular/ear_phenot0.96087659
70MP0003136_yellow_coat_color0.95827960
71MP0001348_abnormal_lacrimal_gland0.95795402
72MP0001545_abnormal_hematopoietic_system0.95773679
73MP0005397_hematopoietic_system_phenotyp0.95773679
74MP0009697_abnormal_copulation0.95556628
75MP0000372_irregular_coat_pigmentation0.95245655
76MP0001286_abnormal_eye_development0.95172219
77MP0009672_abnormal_birth_weight0.94162880
78MP0000477_abnormal_intestine_morphology0.93960686
79MP0010630_abnormal_cardiac_muscle0.92367627
80MP0002210_abnormal_sex_determination0.90675684
81MP0000428_abnormal_craniofacial_morphol0.89779587
82MP0004084_abnormal_cardiac_muscle0.88757788
83MP0006036_abnormal_mitochondrial_physio0.88565334
84MP0002111_abnormal_tail_morphology0.85348881
85MP0003315_abnormal_perineum_morphology0.84471066
86MP0001915_intracranial_hemorrhage0.84221085
87MP0002722_abnormal_immune_system0.83901669
88MP0005666_abnormal_adipose_tissue0.83375279
89MP0001881_abnormal_mammary_gland0.82399888
90MP0003937_abnormal_limbs/digits/tail_de0.81130356
91MP0000858_altered_metastatic_potential0.80271913
92MP0002398_abnormal_bone_marrow0.79568736
93MP0004087_abnormal_muscle_fiber0.79503678
94MP0002092_abnormal_eye_morphology0.78941231
95MP0000358_abnormal_cell_content/0.78556167
96MP0000689_abnormal_spleen_morphology0.77350061
97MP0005257_abnormal_intraocular_pressure0.76839121
98MP0002796_impaired_skin_barrier0.76300116
99MP0003121_genomic_imprinting0.75509352
100MP0002653_abnormal_ependyma_morphology0.73049730
101MP0000579_abnormal_nail_morphology0.72802790
102MP0002697_abnormal_eye_size0.72628430
103MP0006054_spinal_hemorrhage0.72406415
104MP0003950_abnormal_plasma_membrane0.72142988
105MP0005621_abnormal_cell_physiology0.72141170
106MP0005451_abnormal_body_composition0.70871630
107MP0005384_cellular_phenotype0.70640998
108MP0010155_abnormal_intestine_physiology0.70157298
109MP0003866_abnormal_defecation0.69127211
110MP0003453_abnormal_keratinocyte_physiol0.68613608
111MP0003115_abnormal_respiratory_system0.68236720
112MP0002877_abnormal_melanocyte_morpholog0.68210069
113MP0002269_muscular_atrophy0.68103835
114MP0002060_abnormal_skin_morphology0.67945338
115MP0003436_decreased_susceptibility_to0.67407619
116MP0004133_heterotaxia0.67387052
117MP0003861_abnormal_nervous_system0.67026603
118MP0000266_abnormal_heart_morphology0.66660675
119MP0000432_abnormal_head_morphology0.66380564
120MP0003942_abnormal_urinary_system0.65945435
121MP0009703_decreased_birth_body0.65361952
122MP0002925_abnormal_cardiovascular_devel0.65321942
123MP0001661_extended_life_span0.65261136
124MP0010234_abnormal_vibrissa_follicle0.64836195
125MP0001727_abnormal_embryo_implantation0.64735586
126MP0001293_anophthalmia0.64259606
127MP0000627_abnormal_mammary_gland0.63828689
128MP0001186_pigmentation_phenotype0.63389176
129MP0001145_abnormal_male_reproductive0.63365374
130MP0001243_abnormal_dermal_layer0.63015088
131MP0000678_abnormal_parathyroid_gland0.61316333
132MP0001216_abnormal_epidermal_layer0.60833520
133MP0002163_abnormal_gland_morphology0.60155533
134MP0000762_abnormal_tongue_morphology0.59631174
135MP0005083_abnormal_biliary_tract0.59191623
136MP0003755_abnormal_palate_morphology0.59103787
137MP0001929_abnormal_gametogenesis0.58956229

Predicted human phenotypes

RankGene SetZ-score
1Chromosomal breakage induced by crosslinking agents (HP:0003221)4.26269580
2Ependymoma (HP:0002888)4.04558224
3Aplasia/Hypoplasia of the sacrum (HP:0008517)3.51922833
4Proximal placement of thumb (HP:0009623)3.48021948
5Reticulocytopenia (HP:0001896)3.36868624
6Deviation of the thumb (HP:0009603)3.36761006
7Selective tooth agenesis (HP:0001592)3.35917114
8Trismus (HP:0000211)3.32920614
9Multiple enchondromatosis (HP:0005701)3.14927337
10Microvesicular hepatic steatosis (HP:0001414)3.12054381
11Abnormality of cells of the erythroid lineage (HP:0012130)3.07141834
12Degeneration of anterior horn cells (HP:0002398)3.01075481
13Abnormality of the anterior horn cell (HP:0006802)3.01075481
14Meckel diverticulum (HP:0002245)2.92553111
15Abnormality of the preputium (HP:0100587)2.86528456
16Carpal bone hypoplasia (HP:0001498)2.77451654
17Patellar aplasia (HP:0006443)2.76757157
18Oral leukoplakia (HP:0002745)2.76562197
19Impulsivity (HP:0100710)2.74301582
20Astrocytoma (HP:0009592)2.73883022
21Abnormality of the astrocytes (HP:0100707)2.73883022
22Medulloblastoma (HP:0002885)2.72146763
23Abnormality of the ileum (HP:0001549)2.71227011
24Aplasia/Hypoplasia of the patella (HP:0006498)2.71084550
25Cerebral hypomyelination (HP:0006808)2.67938835
26Abnormal number of erythroid precursors (HP:0012131)2.67199837
27Progressive external ophthalmoplegia (HP:0000590)2.62072888
28Abnormality of glycolysis (HP:0004366)2.55051058
29Increased nuchal translucency (HP:0010880)2.47838194
30Rhabdomyosarcoma (HP:0002859)2.47348623
31Colon cancer (HP:0003003)2.45379651
32Neoplasm of the pancreas (HP:0002894)2.42876579
33Overlapping toe (HP:0001845)2.42477406
34Aplasia/Hypoplasia of the uvula (HP:0010293)2.37937456
35Macrocytic anemia (HP:0001972)2.34371373
36Cortical dysplasia (HP:0002539)2.34324713
37Difficulty climbing stairs (HP:0003551)2.32845750
38Acute necrotizing encephalopathy (HP:0006965)2.31275237
39Overriding aorta (HP:0002623)2.30851170
40Atresia of the external auditory canal (HP:0000413)2.30449420
41Increased hepatocellular lipid droplets (HP:0006565)2.30240919
42Volvulus (HP:0002580)2.27431014
43Rough bone trabeculation (HP:0100670)2.27040907
44Increased serum pyruvate (HP:0003542)2.26792477
45Glioma (HP:0009733)2.26337023
46Acute encephalopathy (HP:0006846)2.25089114
47Abnormal number of incisors (HP:0011064)2.22109290
48Abnormal gallbladder physiology (HP:0012438)2.22082033
49Cholecystitis (HP:0001082)2.22082033
50Breast hypoplasia (HP:0003187)2.20974983
51Abnormal mitochondria in muscle tissue (HP:0008316)2.20425302
52Premature ovarian failure (HP:0008209)2.15795116
53Adenoma sebaceum (HP:0009720)2.15782181
54Angiofibromas (HP:0010615)2.15782181
55Basal cell carcinoma (HP:0002671)2.15586600
56Abnormality of the calcaneus (HP:0008364)2.14859753
57Agnosia (HP:0010524)2.13800343
58Increased connective tissue (HP:0009025)2.13403269
59Insomnia (HP:0100785)2.13208467
60Biliary tract neoplasm (HP:0100574)2.13176955
61Renal duplication (HP:0000075)2.12122603
62Hypoplasia of the capital femoral epiphysis (HP:0003090)2.11669362
63Birth length less than 3rd percentile (HP:0003561)2.11667279
64Abnormality of the carotid arteries (HP:0005344)2.11468091
65Ankle contracture (HP:0006466)2.08472160
66Vertebral clefting (HP:0008428)2.08385783
67Thrombocytosis (HP:0001894)2.07713289
68Absent thumb (HP:0009777)2.07628365
6911 pairs of ribs (HP:0000878)2.06019964
70Missing ribs (HP:0000921)2.05936610
71Aplasia/hypoplasia of the humerus (HP:0006507)2.03582700
72Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.02066769
73Cleft eyelid (HP:0000625)2.01560317
74Metaphyseal cupping (HP:0003021)2.01557544
75Myelodysplasia (HP:0002863)2.01295234
76Nephroblastoma (Wilms tumor) (HP:0002667)2.01275107
77Neoplasm of striated muscle (HP:0009728)2.00550998
78Facial cleft (HP:0002006)1.99670657
79Pallor (HP:0000980)1.99176394
80Horseshoe kidney (HP:0000085)1.97936501
81Pelvic girdle muscle weakness (HP:0003749)1.96112083
82Abnormality of reticulocytes (HP:0004312)1.96030553
83Squamous cell carcinoma (HP:0002860)1.94986504
84Lipid accumulation in hepatocytes (HP:0006561)1.93948282
85Ulnar deviation of the wrist (HP:0003049)1.92829955
86Preauricular skin tag (HP:0000384)1.92617762
87Prominent nose (HP:0000448)1.92000555
88Absent radius (HP:0003974)1.91287021
89Sparse eyelashes (HP:0000653)1.90680809
90Spastic diplegia (HP:0001264)1.90457487
91Esophageal atresia (HP:0002032)1.89657248
92Rhabdomyolysis (HP:0003201)1.89160769
93Urethral obstruction (HP:0000796)1.88836968
94Duodenal stenosis (HP:0100867)1.88796342
95Small intestinal stenosis (HP:0012848)1.88796342
96Elfin facies (HP:0004428)1.87019266
97Blepharitis (HP:0000498)1.85339553
98Ulnar bowing (HP:0003031)1.83046426
99Abnormal lung lobation (HP:0002101)1.82915636
100Choanal atresia (HP:0000453)1.82874158
101Increased CSF lactate (HP:0002490)1.82723654
102Absent epiphyses (HP:0010577)1.82209110
103Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)1.82209110
104Skin tags (HP:0010609)1.82185235
105Increased serum lactate (HP:0002151)1.81326586
106Aplasia/Hypoplasia involving the carpal bones (HP:0006502)1.81291711
107Embryonal renal neoplasm (HP:0011794)1.79468966
108Shoulder girdle muscle weakness (HP:0003547)1.79395508
109Ectopic kidney (HP:0000086)1.79279849
110High pitched voice (HP:0001620)1.78461974
111High anterior hairline (HP:0009890)1.78391493
112Nasolacrimal duct obstruction (HP:0000579)1.77722475
113Abnormality of homocysteine metabolism (HP:0010919)1.77453640
114Homocystinuria (HP:0002156)1.77453640
115Hyperacusis (HP:0010780)1.76809737
116Absent forearm bone (HP:0003953)1.76805347
117Aplasia involving forearm bones (HP:0009822)1.76805347
118Amaurosis fugax (HP:0100576)1.76690940
119Abnormality of the labia minora (HP:0012880)1.76672066
120Short thumb (HP:0009778)1.76562007
121Short humerus (HP:0005792)1.76033133
122Atrophy/Degeneration involving motor neurons (HP:0007373)1.75459595
123Myopathic facies (HP:0002058)1.75069158
124Progressive muscle weakness (HP:0003323)1.74805607
125Ventricular tachycardia (HP:0004756)1.74179843
126Respiratory difficulties (HP:0002880)1.73301202
127Glossoptosis (HP:0000162)1.73032261
128Personality changes (HP:0000751)1.72759724
129Muscle fibrillation (HP:0010546)1.71996439
130Abnormality of cochlea (HP:0000375)1.70459744
131Secondary amenorrhea (HP:0000869)1.70309304
132Rib fusion (HP:0000902)1.69734532
133Muscle fiber splitting (HP:0003555)1.69201592
134Increased density of long bones (HP:0006392)1.68876170
135Abnormality of the umbilical cord (HP:0010881)1.68785746
136Cafe-au-lait spot (HP:0000957)1.68768936
137Chromsome breakage (HP:0040012)1.68309007
138Duplication of thumb phalanx (HP:0009942)1.67075877
139Cerebral edema (HP:0002181)1.66104276
140Upper limb muscle weakness (HP:0003484)1.64139528
141Long eyelashes (HP:0000527)1.63008813
142Exercise intolerance (HP:0003546)1.61761059
143Upper limb amyotrophy (HP:0009129)1.60853072
144Distal upper limb amyotrophy (HP:0007149)1.60853072
145Reduced antithrombin III activity (HP:0001976)1.60609701
146Sparse lateral eyebrow (HP:0005338)1.60573535
147Abnormality of chromosome stability (HP:0003220)1.60221616
148Increased intramyocellular lipid droplets (HP:0012240)1.59869634
149Hand muscle atrophy (HP:0009130)1.59627100
150Hypoplastic pelvis (HP:0008839)1.59595635
151Tracheoesophageal fistula (HP:0002575)1.59509083
152Malignant gastrointestinal tract tumors (HP:0006749)1.58046151
153Gastrointestinal carcinoma (HP:0002672)1.58046151
154Short palpebral fissure (HP:0012745)1.57418248
155Pseudobulbar signs (HP:0002200)1.57380344
156Rectal prolapse (HP:0002035)1.57099709
157Premature graying of hair (HP:0002216)1.56010085
158Abnormality of the motor neurons (HP:0002450)1.54645748

Predicted kinase interactions (KEA)

RankGene SetZ-score
1EEF2K4.30255447
2VRK23.47685464
3CDC73.33382953
4CDK123.07834739
5BUB12.93740443
6SMG12.88542811
7NEK22.59359562
8MAP3K102.57356007
9PKN22.52465617
10TRIB32.41743108
11WEE12.31224795
12RPS6KB22.23811444
13TSSK62.17606186
14NEK11.95812884
15PBK1.88107506
16STK101.87679599
17TAF11.83190553
18IRAK31.82993227
19TTK1.76062676
20CDK41.70864708
21NME21.69228183
22STK38L1.66956344
23SRPK11.66560100
24STK161.59545494
25TTN1.59294669
26NME11.58083299
27MST41.57242023
28TESK21.52793695
29MAPKAPK31.50954683
30EPHA21.46633295
31EIF2AK11.45924301
32AURKB1.44476449
33DMPK1.44261645
34PASK1.43901361
35PLK11.43724016
36PAK41.43147775
37MAP3K81.37432980
38LRRK21.31778990
39CDK71.31482491
40MKNK11.27126149
41MAP4K11.22901521
42ALK1.22481280
43RPS6KA41.18073511
44CHEK11.16211165
45PDK21.16069329
46ATR1.11054342
47NUAK11.09555425
48ILK1.09393910
49MTOR1.08450472
50PNCK1.04814830
51TLK11.04713608
52CDK81.02492237
53MAP2K20.97864214
54SCYL20.97049524
55AURKA0.95247439
56SIK10.93546410
57CDK60.88556010
58PLK30.88385820
59VRK10.88229154
60PLK40.87448952
61MKNK20.87350726
62CLK10.87242148
63STK40.85708805
64FGFR40.85435224
65CDK20.84436907
66CHEK20.84434572
67LATS20.83849542
68PTK60.83530359
69MAP3K70.83203085
70INSRR0.81829671
71PAK10.79687003
72MAP2K30.79479375
73BRD40.79338499
74PAK20.76213764
75ACVR1B0.76090198
76PIM10.75754954
77DYRK30.75336104
78RAF10.75305663
79STK30.74271828
80TGFBR10.70790259
81BRAF0.70769946
82TESK10.69969306
83EIF2AK20.69722313
84BMX0.69326585
85CSNK2A20.67905496
86ERN10.67792306
87ATM0.65516538
88CAMK1D0.65288294
89BRSK20.63914676
90ERBB40.62696587
91PIM20.62679411
92CAMK1G0.61620725
93CDK90.58870258
94TAOK10.58527479
95TEC0.56718755
96LATS10.53974797
97PTK20.53527542
98AKT20.53409049
99GRK60.53327967
100ZAP700.51959737
101FGFR10.51857925
102CDK10.50348198
103* CSNK1E0.49993787
104ZAK0.48906673
105PRKCI0.48846955
106FLT30.48730546
107PIK3CA0.48011521
108TRPM70.47400322
109WNK40.46892158
110EIF2AK30.45431600
111ICK0.45224008
112* CSNK2A10.44541661
113MELK0.42697638
114MAPK140.42631405
115PDK30.41287388
116PDK40.41287388
117RPS6KA10.40355706
118BRSK10.39294598
119MET0.39131416
120TYRO30.38150865
121BCKDK0.36828138
122BTK0.36681280
123TAOK20.36213029
124MAPKAPK20.35326273
125MAPK110.35204766
126EPHB20.35155714
127CSNK1D0.34662171
128PRKDC0.34435298
129CDK11A0.32362308
130GSK3B0.31832586
131MST1R0.31255767
132ABL20.29321150
133MAP3K90.27491057
134PDGFRA0.27426224

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030304.25520141
2Mismatch repair_Homo sapiens_hsa034303.69721705
3Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030083.52169684
4Ribosome_Homo sapiens_hsa030103.45150911
5Spliceosome_Homo sapiens_hsa030403.34756094
6RNA transport_Homo sapiens_hsa030133.27575186
7One carbon pool by folate_Homo sapiens_hsa006702.82509424
8Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009702.67097986
9RNA polymerase_Homo sapiens_hsa030202.56035590
10Base excision repair_Homo sapiens_hsa034102.42272626
11Cell cycle_Homo sapiens_hsa041102.36976113
12Homologous recombination_Homo sapiens_hsa034402.31387303
13Nucleotide excision repair_Homo sapiens_hsa034202.13190998
14Proteasome_Homo sapiens_hsa030501.94404080
15Pyrimidine metabolism_Homo sapiens_hsa002401.85885258
16mRNA surveillance pathway_Homo sapiens_hsa030151.81638579
17Non-homologous end-joining_Homo sapiens_hsa034501.53493893
18p53 signaling pathway_Homo sapiens_hsa041151.43238365
19RNA degradation_Homo sapiens_hsa030181.42271889
20Biosynthesis of amino acids_Homo sapiens_hsa012301.33628409
21Fanconi anemia pathway_Homo sapiens_hsa034601.30618103
22Antigen processing and presentation_Homo sapiens_hsa046121.28000246
23Parkinsons disease_Homo sapiens_hsa050121.26288590
24Oxidative phosphorylation_Homo sapiens_hsa001901.24901784
25Sulfur relay system_Homo sapiens_hsa041221.22510937
26Carbon metabolism_Homo sapiens_hsa012001.20683264
27Epstein-Barr virus infection_Homo sapiens_hsa051691.18880494
28Huntingtons disease_Homo sapiens_hsa050161.16804958
29Basal transcription factors_Homo sapiens_hsa030221.12755220
302-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.12497440
31Pentose phosphate pathway_Homo sapiens_hsa000301.12328304
32Viral carcinogenesis_Homo sapiens_hsa052031.11895223
33Protein export_Homo sapiens_hsa030601.11883911
34Cysteine and methionine metabolism_Homo sapiens_hsa002700.99900500
35Selenocompound metabolism_Homo sapiens_hsa004500.94635116
36Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.93200897
37Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.92227686
38Adherens junction_Homo sapiens_hsa045200.91837766
39Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.91418770
40Steroid biosynthesis_Homo sapiens_hsa001000.89576687
41MicroRNAs in cancer_Homo sapiens_hsa052060.87246273
42Thyroid cancer_Homo sapiens_hsa052160.86483473
43Small cell lung cancer_Homo sapiens_hsa052220.86195575
44Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.85322513
45HTLV-I infection_Homo sapiens_hsa051660.84730052
46Systemic lupus erythematosus_Homo sapiens_hsa053220.84485845
47Herpes simplex infection_Homo sapiens_hsa051680.82729442
48Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.82672591
49Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.81548605
50Purine metabolism_Homo sapiens_hsa002300.81072875
51Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.80755426
52Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.79697347
53Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.79082567
54Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.78584100
55Folate biosynthesis_Homo sapiens_hsa007900.76879078
56Chronic myeloid leukemia_Homo sapiens_hsa052200.76589309
57Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.75237718
58Viral myocarditis_Homo sapiens_hsa054160.74824178
59Notch signaling pathway_Homo sapiens_hsa043300.74717495
60Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.74104479
61Cyanoamino acid metabolism_Homo sapiens_hsa004600.69705214
62Acute myeloid leukemia_Homo sapiens_hsa052210.68218450
63Bladder cancer_Homo sapiens_hsa052190.67604416
64Hippo signaling pathway_Homo sapiens_hsa043900.67504253
65Central carbon metabolism in cancer_Homo sapiens_hsa052300.66214755
66Alzheimers disease_Homo sapiens_hsa050100.65733455
67Drug metabolism - other enzymes_Homo sapiens_hsa009830.65457838
68HIF-1 signaling pathway_Homo sapiens_hsa040660.64945903
69Apoptosis_Homo sapiens_hsa042100.64895611
70Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.63904042
71Lysine degradation_Homo sapiens_hsa003100.63805232
72Pyruvate metabolism_Homo sapiens_hsa006200.62107465
73Legionellosis_Homo sapiens_hsa051340.61313071
74N-Glycan biosynthesis_Homo sapiens_hsa005100.60072272
75Fructose and mannose metabolism_Homo sapiens_hsa000510.60043304
76Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.59457660
77Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.58898073
78Oocyte meiosis_Homo sapiens_hsa041140.58257307
79mTOR signaling pathway_Homo sapiens_hsa041500.57478186
80Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.57019028
81Tight junction_Homo sapiens_hsa045300.56721123
82Galactose metabolism_Homo sapiens_hsa000520.56035475
83Basal cell carcinoma_Homo sapiens_hsa052170.52791126
84Leukocyte transendothelial migration_Homo sapiens_hsa046700.50521585
85Proteoglycans in cancer_Homo sapiens_hsa052050.50498727
86NF-kappa B signaling pathway_Homo sapiens_hsa040640.49382244
87Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.47498867
88Primary immunodeficiency_Homo sapiens_hsa053400.46804564
89Transcriptional misregulation in cancer_Homo sapiens_hsa052020.44921301
90Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.44177736
91Metabolic pathways_Homo sapiens_hsa011000.39607498
92Colorectal cancer_Homo sapiens_hsa052100.39333406
93Fatty acid elongation_Homo sapiens_hsa000620.38306086
94Glutathione metabolism_Homo sapiens_hsa004800.37518083
95Endometrial cancer_Homo sapiens_hsa052130.37481252
96Fat digestion and absorption_Homo sapiens_hsa049750.37296643
97Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.37163461
98Intestinal immune network for IgA production_Homo sapiens_hsa046720.35925120
99Measles_Homo sapiens_hsa051620.35816329
100Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.35668360
101Pathways in cancer_Homo sapiens_hsa052000.35648329
102NOD-like receptor signaling pathway_Homo sapiens_hsa046210.32445907
103Leishmaniasis_Homo sapiens_hsa051400.30935840
104AMPK signaling pathway_Homo sapiens_hsa041520.30766020
105Shigellosis_Homo sapiens_hsa051310.30573862
106Prostate cancer_Homo sapiens_hsa052150.30482560
107Wnt signaling pathway_Homo sapiens_hsa043100.30208410
108TGF-beta signaling pathway_Homo sapiens_hsa043500.28886793
109Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.28810294
110Non-small cell lung cancer_Homo sapiens_hsa052230.28625605
111Hepatitis B_Homo sapiens_hsa051610.28363114
112Vitamin B6 metabolism_Homo sapiens_hsa007500.27694824
113T cell receptor signaling pathway_Homo sapiens_hsa046600.26920138
114Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.26873403
115Propanoate metabolism_Homo sapiens_hsa006400.26666692
116Arginine and proline metabolism_Homo sapiens_hsa003300.26233955
117Toxoplasmosis_Homo sapiens_hsa051450.25612200
118Cardiac muscle contraction_Homo sapiens_hsa042600.25540082
119Focal adhesion_Homo sapiens_hsa045100.24048295
120Vitamin digestion and absorption_Homo sapiens_hsa049770.22498927
121Pancreatic cancer_Homo sapiens_hsa052120.22400228
122Arginine biosynthesis_Homo sapiens_hsa002200.16190896
123Prion diseases_Homo sapiens_hsa050200.13888090

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