Rank | Gene Set | Z-score |
---|---|---|
1 | DNA deamination (GO:0045006) | 5.61911098 |
2 | ribosomal small subunit assembly (GO:0000028) | 5.48979436 |
3 | axonemal dynein complex assembly (GO:0070286) | 5.38877082 |
4 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 5.01662526 |
5 | viral transcription (GO:0019083) | 4.80903624 |
6 | calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules (GO:0016338) | 4.75633543 |
7 | oxidative phosphorylation (GO:0006119) | 4.69522523 |
8 | translational termination (GO:0006415) | 4.64615195 |
9 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 4.47629612 |
10 | ATP synthesis coupled proton transport (GO:0015986) | 4.47629612 |
11 | epithelial cilium movement (GO:0003351) | 4.35982886 |
12 | maturation of SSU-rRNA (GO:0030490) | 4.35360024 |
13 | translational elongation (GO:0006414) | 4.34157968 |
14 | ribosomal small subunit biogenesis (GO:0042274) | 4.33273353 |
15 | cilium movement (GO:0003341) | 4.28225086 |
16 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 4.24030563 |
17 | cotranslational protein targeting to membrane (GO:0006613) | 4.14094520 |
18 | protein targeting to ER (GO:0045047) | 4.10826852 |
19 | protein localization to endoplasmic reticulum (GO:0070972) | 3.98442805 |
20 | nucleobase biosynthetic process (GO:0046112) | 3.89809480 |
21 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 3.87473928 |
22 | behavioral response to nicotine (GO:0035095) | 3.84166167 |
23 | purine nucleobase biosynthetic process (GO:0009113) | 3.82754580 |
24 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.79957559 |
25 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.79957559 |
26 | proteasome assembly (GO:0043248) | 3.78576329 |
27 | translational initiation (GO:0006413) | 3.73829207 |
28 | axoneme assembly (GO:0035082) | 3.71062438 |
29 | respiratory electron transport chain (GO:0022904) | 3.69202590 |
30 | viral life cycle (GO:0019058) | 3.64712297 |
31 | epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287) | 3.64005096 |
32 | motile cilium assembly (GO:0044458) | 3.63387188 |
33 | electron transport chain (GO:0022900) | 3.61489424 |
34 | ribosomal large subunit biogenesis (GO:0042273) | 3.61100905 |
35 | cilium or flagellum-dependent cell motility (GO:0001539) | 3.60743356 |
36 | negative regulation of T cell differentiation in thymus (GO:0033085) | 3.57185189 |
37 | cellular protein complex disassembly (GO:0043624) | 3.56563479 |
38 | translation (GO:0006412) | 3.51208916 |
39 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 3.48485568 |
40 | formation of translation preinitiation complex (GO:0001731) | 3.48008946 |
41 | telomere maintenance via semi-conservative replication (GO:0032201) | 3.45151350 |
42 | GDP-mannose metabolic process (GO:0019673) | 3.43760507 |
43 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 3.43161645 |
44 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 3.42521712 |
45 | NADH dehydrogenase complex assembly (GO:0010257) | 3.42521712 |
46 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 3.42521712 |
47 | ribonucleoprotein complex biogenesis (GO:0022613) | 3.37588355 |
48 | pseudouridine synthesis (GO:0001522) | 3.37496970 |
49 | regulation of cell proliferation involved in kidney development (GO:1901722) | 3.36211742 |
50 | L-methionine biosynthetic process from methylthioadenosine (GO:0019509) | 3.35093630 |
51 | GTP biosynthetic process (GO:0006183) | 3.34320694 |
52 | respiratory chain complex IV assembly (GO:0008535) | 3.33597244 |
53 | primary alcohol catabolic process (GO:0034310) | 3.32692623 |
54 | folic acid metabolic process (GO:0046655) | 3.32343676 |
55 | intestinal epithelial cell development (GO:0060576) | 3.30962061 |
56 | DNA strand elongation involved in DNA replication (GO:0006271) | 3.30918954 |
57 | deoxyribonucleoside monophosphate metabolic process (GO:0009162) | 3.30822175 |
58 | preassembly of GPI anchor in ER membrane (GO:0016254) | 3.29566991 |
59 | keratinocyte development (GO:0003334) | 3.26984080 |
60 | nucleoside transmembrane transport (GO:1901642) | 3.25451293 |
61 | iron-sulfur cluster assembly (GO:0016226) | 3.25298972 |
62 | metallo-sulfur cluster assembly (GO:0031163) | 3.25298972 |
63 | protein-cofactor linkage (GO:0018065) | 3.25015068 |
64 | regulation of mitochondrial translation (GO:0070129) | 3.22566995 |
65 | cornea development in camera-type eye (GO:0061303) | 3.21892128 |
66 | protein complex biogenesis (GO:0070271) | 3.19880243 |
67 | amino acid salvage (GO:0043102) | 3.18693634 |
68 | L-methionine salvage (GO:0071267) | 3.18693634 |
69 | L-methionine biosynthetic process (GO:0071265) | 3.18693634 |
70 | cellular component biogenesis (GO:0044085) | 3.18169570 |
71 | ubiquinone biosynthetic process (GO:0006744) | 3.17757417 |
72 | quinone biosynthetic process (GO:1901663) | 3.17757417 |
73 | DNA strand elongation (GO:0022616) | 3.16194657 |
74 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.15820679 |
75 | sulfur amino acid catabolic process (GO:0000098) | 3.15490646 |
76 | aerobic respiration (GO:0009060) | 3.14752834 |
77 | NADH metabolic process (GO:0006734) | 3.13700089 |
78 | base-excision repair, AP site formation (GO:0006285) | 3.13631183 |
79 | water-soluble vitamin biosynthetic process (GO:0042364) | 3.09627881 |
80 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 3.07143755 |
81 | termination of RNA polymerase III transcription (GO:0006386) | 3.07143755 |
82 | cellular ketone body metabolic process (GO:0046950) | 3.06698728 |
83 | galactose catabolic process (GO:0019388) | 3.05361975 |
84 | regulation of cellular amino acid metabolic process (GO:0006521) | 3.05346994 |
85 | tricarboxylic acid cycle (GO:0006099) | 3.03672038 |
86 | desmosome organization (GO:0002934) | 3.02714960 |
87 | protein complex disassembly (GO:0043241) | 3.01782814 |
88 | inner mitochondrial membrane organization (GO:0007007) | 3.01681414 |
89 | nitric oxide biosynthetic process (GO:0006809) | 2.99988381 |
90 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 2.99760270 |
91 | ribosome biogenesis (GO:0042254) | 2.99181199 |
92 | nucleoside diphosphate phosphorylation (GO:0006165) | 2.99010159 |
93 | rRNA modification (GO:0000154) | 2.98731117 |
94 | trivalent inorganic anion homeostasis (GO:0072506) | 2.97969326 |
95 | phosphate ion homeostasis (GO:0055062) | 2.97969326 |
96 | peptidyl-histidine modification (GO:0018202) | 2.97717551 |
97 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 2.95672910 |
98 | branched-chain amino acid catabolic process (GO:0009083) | 2.95173712 |
99 | chaperone-mediated protein transport (GO:0072321) | 2.94669772 |
100 | glycine metabolic process (GO:0006544) | 2.91651067 |
101 | nucleoside salvage (GO:0043174) | 2.91126522 |
102 | negative regulation of transcription elongation from RNA polymerase II promoter (GO:0034244) | 2.90821891 |
103 | rRNA processing (GO:0006364) | 2.90374693 |
104 | macromolecular complex disassembly (GO:0032984) | 2.90229294 |
105 | UTP biosynthetic process (GO:0006228) | 2.89362593 |
106 | protein localization to cilium (GO:0061512) | 2.87934015 |
107 | telomere maintenance via recombination (GO:0000722) | 2.87550790 |
108 | mesonephros development (GO:0001823) | 2.86559592 |
109 | tRNA modification (GO:0006400) | 2.86086234 |
110 | nucleobase-containing small molecule interconversion (GO:0015949) | 2.85704893 |
111 | ear development (GO:0043583) | 2.85452773 |
112 | pyrimidine nucleoside triphosphate metabolic process (GO:0009147) | 2.84485081 |
113 | C-terminal protein lipidation (GO:0006501) | 2.84333931 |
114 | protein targeting to mitochondrion (GO:0006626) | 2.82407550 |
115 | pteridine-containing compound biosynthetic process (GO:0042559) | 2.82358262 |
116 | valine metabolic process (GO:0006573) | 2.80886651 |
117 | regulation of autophagic vacuole assembly (GO:2000785) | 2.80003782 |
118 | ATP biosynthetic process (GO:0006754) | 2.79731533 |
119 | GPI anchor biosynthetic process (GO:0006506) | 2.79165414 |
120 | rRNA metabolic process (GO:0016072) | 2.79072648 |
121 | regulation of cellular respiration (GO:0043457) | 2.78570117 |
122 | vitamin transmembrane transport (GO:0035461) | 2.78131562 |
123 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO: | 2.77480682 |
124 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 2.76186235 |
125 | establishment of protein localization to mitochondrion (GO:0072655) | 2.75889597 |
126 | L-phenylalanine metabolic process (GO:0006558) | 2.75848646 |
127 | erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221) | 2.75848646 |
128 | mannosylation (GO:0097502) | 2.75491818 |
129 | purine ribonucleoside monophosphate biosynthetic process (GO:0009168) | 2.75355780 |
130 | purine nucleoside monophosphate biosynthetic process (GO:0009127) | 2.75355780 |
131 | hydrogen ion transmembrane transport (GO:1902600) | 2.75003298 |
132 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 2.74932468 |
133 | negative regulation of ligase activity (GO:0051352) | 2.74932468 |
134 | cytochrome complex assembly (GO:0017004) | 2.74377314 |
135 | serine family amino acid biosynthetic process (GO:0009070) | 2.74163540 |
136 | purine nucleoside triphosphate biosynthetic process (GO:0009145) | 2.73411705 |
137 | ubiquinone metabolic process (GO:0006743) | 2.72712795 |
138 | ketone body metabolic process (GO:1902224) | 2.72393973 |
139 | ribonucleoside triphosphate biosynthetic process (GO:0009201) | 2.72078908 |
140 | purine ribonucleoside triphosphate biosynthetic process (GO:0009206) | 2.71099161 |
141 | tRNA processing (GO:0008033) | 2.70664774 |
142 | fucose catabolic process (GO:0019317) | 2.70262576 |
143 | L-fucose metabolic process (GO:0042354) | 2.70262576 |
144 | L-fucose catabolic process (GO:0042355) | 2.70262576 |
145 | nucleoside monophosphate biosynthetic process (GO:0009124) | 2.70027999 |
146 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 2.69889835 |
147 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 2.69889835 |
148 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 2.69800327 |
149 | proton transport (GO:0015992) | 2.69779472 |
150 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 2.69507123 |
151 | regulation of cilium movement (GO:0003352) | 2.69438268 |
152 | cysteine metabolic process (GO:0006534) | 2.68108173 |
153 | left/right pattern formation (GO:0060972) | 2.68103607 |
154 | glutathione derivative biosynthetic process (GO:1901687) | 2.67349329 |
155 | glutathione derivative metabolic process (GO:1901685) | 2.67349329 |
156 | aldehyde catabolic process (GO:0046185) | 2.66157730 |
157 | UTP metabolic process (GO:0046051) | 2.64677000 |
158 | negative regulation of kidney development (GO:0090185) | 2.63945462 |
159 | GPI anchor metabolic process (GO:0006505) | 2.62258677 |
160 | pyrimidine deoxyribonucleotide catabolic process (GO:0009223) | 2.62027336 |
161 | hydrogen transport (GO:0006818) | 2.61184581 |
162 | response to food (GO:0032094) | 2.60404170 |
163 | glutathione biosynthetic process (GO:0006750) | 2.59673212 |
164 | galactose metabolic process (GO:0006012) | 2.59431559 |
165 | nucleoside transport (GO:0015858) | 2.58155357 |
166 | intraciliary transport (GO:0042073) | 2.56305825 |
167 | terpenoid biosynthetic process (GO:0016114) | 2.55285120 |
168 | C-terminal protein amino acid modification (GO:0018410) | 2.54630202 |
169 | pyrimidine-containing compound transmembrane transport (GO:0072531) | 2.53823936 |
170 | multicellular organism reproduction (GO:0032504) | 2.52193305 |
171 | rRNA methylation (GO:0031167) | 2.50611263 |
172 | diterpenoid biosynthetic process (GO:0016102) | 2.49008486 |
173 | platelet dense granule organization (GO:0060155) | 2.47636788 |
174 | guanosine-containing compound biosynthetic process (GO:1901070) | 2.46977975 |
Rank | Gene Set | Z-score |
---|---|---|
1 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 5.71627411 |
2 | * EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 4.15139215 |
3 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 4.09254337 |
4 | E2F7_22180533_ChIP-Seq_HELA_Human | 3.90247380 |
5 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 3.50979401 |
6 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 3.45871785 |
7 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 3.22217894 |
8 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.10833856 |
9 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 3.06049352 |
10 | * MYC_18358816_ChIP-ChIP_MESCs_Mouse | 3.05192082 |
11 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 3.03124453 |
12 | ESR1_21235772_ChIP-Seq_MCF-7_Human | 2.98658873 |
13 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 2.97796436 |
14 | ESR1_17901129_ChIP-ChIP_LIVER_Mouse | 2.76993536 |
15 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.76758797 |
16 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 2.75842402 |
17 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 2.62290153 |
18 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.58552549 |
19 | * MYC_19030024_ChIP-ChIP_MESCs_Mouse | 2.53165297 |
20 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 2.51978848 |
21 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 2.50180012 |
22 | ESR1_20079471_ChIP-ChIP_T-47D_Human | 2.39692658 |
23 | CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human | 2.39232637 |
24 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 2.26895147 |
25 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 2.26264594 |
26 | ESR1_15608294_ChIP-ChIP_MCF-7_Human | 2.24699784 |
27 | * XRN2_22483619_ChIP-Seq_HELA_Human | 2.24283046 |
28 | * E2F1_18555785_ChIP-Seq_MESCs_Mouse | 2.22110855 |
29 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.18541431 |
30 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.16267737 |
31 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.15901383 |
32 | DCP1A_22483619_ChIP-Seq_HELA_Human | 2.10171693 |
33 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 2.08115690 |
34 | * SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.99229776 |
35 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 1.97516551 |
36 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.97388873 |
37 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.95838308 |
38 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.93168227 |
39 | * NELFA_20434984_ChIP-Seq_ESCs_Mouse | 1.92621181 |
40 | * CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 1.91397686 |
41 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.89635882 |
42 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.86802356 |
43 | * TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.84511712 |
44 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.82249138 |
45 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.77269619 |
46 | * RACK7_27058665_Chip-Seq_MCF-7_Human | 1.74899737 |
47 | VDR_22108803_ChIP-Seq_LS180_Human | 1.73757316 |
48 | * PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.72580756 |
49 | ZNF652_21678463_ChIP-ChIP_ZR75-1_Human | 1.71985432 |
50 | PPARA_22158963_ChIP-Seq_LIVER_Mouse | 1.69193799 |
51 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.66891636 |
52 | * FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 1.63939719 |
53 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.62778792 |
54 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.61360000 |
55 | ERA_21632823_ChIP-Seq_H3396_Human | 1.60198799 |
56 | RXR_22158963_ChIP-Seq_LIVER_Mouse | 1.58015111 |
57 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 1.57369973 |
58 | STAT3_1855785_ChIP-Seq_MESCs_Mouse | 1.55112340 |
59 | * HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.54466648 |
60 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.53513224 |
61 | P68_20966046_ChIP-Seq_HELA_Human | 1.52791323 |
62 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 1.52186227 |
63 | * ERG_20887958_ChIP-Seq_HPC-7_Mouse | 1.50736026 |
64 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 1.50631620 |
65 | TDRD3_21172665_ChIP-Seq_MCF-7_Human | 1.50481821 |
66 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 1.48541719 |
67 | RUNX1_27514584_Chip-Seq_MCF-7_Human | 1.48161647 |
68 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 1.45152012 |
69 | * CDX2_20551321_ChIP-Seq_CACO-2_Human | 1.44347626 |
70 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.44075480 |
71 | ZFX_18555785_ChIP-Seq_MESCs_Mouse | 1.43206871 |
72 | ELF5_23300383_ChIP-Seq_T47D_Human | 1.40638757 |
73 | * HOXB7_26014856_ChIP-Seq_BT474_Human | 1.40359124 |
74 | * FOXP1_21924763_ChIP-Seq_HESCs_Human | 1.38131552 |
75 | PHF8_20622854_ChIP-Seq_HELA_Human | 1.37615395 |
76 | * EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 1.37419379 |
77 | CTCF_20526341_ChIP-Seq_ESCs_Human | 1.33859748 |
78 | E2F1_20622854_ChIP-Seq_HELA_Human | 1.33543525 |
79 | TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.32362371 |
80 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.31743543 |
81 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.31131393 |
82 | BCL3_23251550_ChIP-Seq_MUSCLE_Mouse | 1.31068747 |
83 | NANOG_18555785_ChIP-Seq_MESCs_Mouse | 1.29786335 |
84 | BMI1_19503595_ChIP-Seq_MEFsC_Mouse | 1.29533215 |
85 | MYCN_18555785_ChIP-Seq_MESCs_Mouse | 1.27945255 |
86 | TFAP2C_20629094_ChIP-Seq_MCF-7_Human | 1.27478298 |
87 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.25321962 |
88 | SMAD2/3_21741376_ChIP-Seq_ESCs_Human | 1.24192912 |
89 | TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse | 1.23694725 |
90 | * GATA3_24758297_ChIP-Seq_MCF-7_Human | 1.23548373 |
91 | * ESRRB_18555785_ChIP-Seq_MESCs_Mouse | 1.22233928 |
92 | AR_21909140_ChIP-Seq_LNCAP_Human | 1.20925416 |
93 | STAT1_20625510_ChIP-Seq_HELA_Human | 1.20701963 |
94 | * SIN3B_21632747_ChIP-Seq_MESCs_Mouse | 1.19315364 |
95 | * BCOR_27268052_Chip-Seq_Bcells_Human | 1.18994607 |
96 | GATA6_25053715_ChIP-Seq_YYC3_Human | 1.18158846 |
97 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 1.18137304 |
98 | CTCF_27219007_Chip-Seq_Bcells_Human | 1.16066038 |
99 | * BCL6_27268052_Chip-Seq_Bcells_Human | 1.16043036 |
100 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 1.15110235 |
101 | GATA4_25053715_ChIP-Seq_YYC3_Human | 1.14460790 |
102 | SREBP2_21459322_ChIP-Seq_LIVER_Mouse | 1.13842479 |
103 | NANOG_20526341_ChIP-Seq_ESCs_Human | 1.13752150 |
104 | P53_21459846_ChIP-Seq_SAOS-2_Human | 1.13571970 |
105 | * RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 1.12979703 |
106 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.12835632 |
107 | * CCND1_20090754_ChIP-ChIP_RETINA_Mouse | 1.10508292 |
108 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.10243675 |
109 | DACH1_20351289_ChIP-Seq_MDA-MB-231_Human | 1.09896518 |
110 | RARB_24833708_ChIP-Seq_LIVER_Mouse | 1.09791256 |
111 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 1.09218458 |
112 | POU5F1_18700969_ChIP-ChIP_MESCs_Mouse | 1.09068787 |
113 | * P300_27268052_Chip-Seq_Bcells_Human | 1.08805565 |
114 | KDM5A_27292631_Chip-Seq_BREAST_Human | 1.07374029 |
115 | ZNF263_19887448_ChIP-Seq_K562_Human | 1.07015704 |
116 | SMC4_20622854_ChIP-Seq_HELA_Human | 1.06747019 |
117 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.06431309 |
118 | HIF1A_21447827_ChIP-Seq_MCF-7_Human | 1.06181042 |
119 | OCT4_20526341_ChIP-Seq_ESCs_Human | 1.05002450 |
120 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.04898830 |
121 | LXR_22292898_ChIP-Seq_THP-1_Human | 1.04865740 |
122 | TAF2_19829295_ChIP-Seq_ESCs_Human | 1.04525739 |
123 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.04256363 |
124 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.04256363 |
125 | VDR_21846776_ChIP-Seq_THP-1_Human | 1.03214099 |
126 | CTCF_18555785_ChIP-Seq_MESCs_Mouse | 1.02995024 |
127 | RAC3_21632823_ChIP-Seq_H3396_Human | 1.02620545 |
128 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.02610855 |
129 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.02529840 |
130 | CTCF_26484167_Chip-Seq_Bcells_Mouse | 1.01409377 |
131 | CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human | 1.01022588 |
132 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 1.00850589 |
133 | TBX5_21415370_ChIP-Seq_HL-1_Mouse | 1.00691178 |
134 | SPI1_23547873_ChIP-Seq_NB4_Human | 1.00589128 |
135 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.00480987 |
136 | SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse | 1.00131703 |
137 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 0.99840706 |
138 | GATA1_22383799_ChIP-Seq_G1ME_Mouse | 0.99836412 |
139 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 0.97281772 |
140 | AHR_22903824_ChIP-Seq_MCF-7_Human | 0.96439349 |
141 | RAD21_21589869_ChIP-Seq_MESCs_Mouse | 0.96167198 |
142 | HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse | 0.96061872 |
143 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 0.95646887 |
144 | TP53_22573176_ChIP-Seq_HFKS_Human | 0.95419367 |
145 | KLF4_18555785_ChIP-Seq_MESCs_Mouse | 0.95370806 |
146 | AR_20517297_ChIP-Seq_VCAP_Human | 0.94530378 |
147 | * NR0B1_18358816_ChIP-ChIP_MESCs_Mouse | 0.94327029 |
148 | P63_20808887_ChIP-Seq_KERATINOCYTES_Human | 0.93659154 |
149 | MYC_22102868_ChIP-Seq_BL_Human | 0.93254410 |
150 | ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 0.92737168 |
151 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 0.92382622 |
152 | YY1_22570637_ChIP-Seq_MALME-3M_Human | 0.89960150 |
153 | GATA1_22025678_ChIP-Seq_K562_Human | 0.88727934 |
154 | SRY_22984422_ChIP-ChIP_TESTIS_Rat | 0.88469490 |
155 | GFI1B_20887958_ChIP-Seq_HPC-7_Mouse | 0.88396249 |
156 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 0.87986404 |
157 | OCT4_18692474_ChIP-Seq_MEFs_Mouse | 0.86661095 |
158 | SIN3A_21632747_ChIP-Seq_MESCs_Mouse | 0.85965509 |
159 | CNOT3_19339689_ChIP-ChIP_MESCs_Mouse | 0.85739461 |
160 | TET1_21451524_ChIP-Seq_MESCs_Mouse | 0.83502774 |
161 | * KLF4_18358816_ChIP-ChIP_MESCs_Mouse | 0.83154510 |
162 | FOXO1_23066095_ChIP-Seq_LIVER_Mouse | 0.83123922 |
163 | DMRT1_21621532_ChIP-ChIP_FETAL_Ovary | 0.83044175 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0003806_abnormal_nucleotide_metabolis | 4.88282249 |
2 | MP0003693_abnormal_embryo_hatching | 3.94914255 |
3 | MP0002139_abnormal_hepatobiliary_system | 3.41436834 |
4 | MP0005360_urolithiasis | 3.33405844 |
5 | MP0006036_abnormal_mitochondrial_physio | 3.26824272 |
6 | MP0005085_abnormal_gallbladder_physiolo | 3.06959081 |
7 | MP0005365_abnormal_bile_salt | 3.06100065 |
8 | MP0008875_abnormal_xenobiotic_pharmacok | 3.00513326 |
9 | MP0009780_abnormal_chondrocyte_physiolo | 2.68883778 |
10 | MP0003186_abnormal_redox_activity | 2.68616308 |
11 | MP0004957_abnormal_blastocyst_morpholog | 2.55396388 |
12 | MP0009379_abnormal_foot_pigmentation | 2.53077890 |
13 | MP0002160_abnormal_reproductive_system | 2.52819514 |
14 | MP0003646_muscle_fatigue | 2.48553156 |
15 | MP0004043_abnormal_pH_regulation | 2.23153731 |
16 | MP0009840_abnormal_foam_cell | 2.22021484 |
17 | MP0002396_abnormal_hematopoietic_system | 2.20544244 |
18 | MP0001764_abnormal_homeostasis | 2.18175234 |
19 | MP0005332_abnormal_amino_acid | 2.16056082 |
20 | MP0002876_abnormal_thyroid_physiology | 2.15939035 |
21 | MP0002277_abnormal_respiratory_mucosa | 2.09635307 |
22 | MP0006035_abnormal_mitochondrial_morpho | 2.06791157 |
23 | MP0002098_abnormal_vibrissa_morphology | 2.06567735 |
24 | MP0002653_abnormal_ependyma_morphology | 1.98821461 |
25 | MP0010030_abnormal_orbit_morphology | 1.97776778 |
26 | MP0005646_abnormal_pituitary_gland | 1.96148353 |
27 | MP0005377_hearing/vestibular/ear_phenot | 1.93081693 |
28 | MP0003878_abnormal_ear_physiology | 1.93081693 |
29 | MP0002736_abnormal_nociception_after | 1.90754922 |
30 | MP0001873_stomach_inflammation | 1.89773556 |
31 | MP0005083_abnormal_biliary_tract | 1.85933538 |
32 | MP0010094_abnormal_chromosome_stability | 1.85685032 |
33 | MP0001666_abnormal_nutrient_absorption | 1.82217763 |
34 | MP0000383_abnormal_hair_follicle | 1.81518677 |
35 | MP0000490_abnormal_crypts_of | 1.78497949 |
36 | MP0000427_abnormal_hair_cycle | 1.78430924 |
37 | MP0003718_maternal_effect | 1.74605661 |
38 | MP0001853_heart_inflammation | 1.72226707 |
39 | MP0010234_abnormal_vibrissa_follicle | 1.70651128 |
40 | MP0008058_abnormal_DNA_repair | 1.70001188 |
41 | MP0002909_abnormal_adrenal_gland | 1.69705540 |
42 | MP0003191_abnormal_cellular_cholesterol | 1.67875809 |
43 | MP0004133_heterotaxia | 1.66522327 |
44 | MP0010329_abnormal_lipoprotein_level | 1.64373164 |
45 | MP0008057_abnormal_DNA_replication | 1.64154629 |
46 | MP0008995_early_reproductive_senescence | 1.63796453 |
47 | MP0003656_abnormal_erythrocyte_physiolo | 1.63591829 |
48 | MP0005389_reproductive_system_phenotype | 1.63186368 |
49 | MP0003077_abnormal_cell_cycle | 1.62773772 |
50 | MP0003123_paternal_imprinting | 1.59313748 |
51 | MP0005319_abnormal_enzyme/_coenzyme | 1.58110975 |
52 | MP0003136_yellow_coat_color | 1.52201113 |
53 | MP0001485_abnormal_pinna_reflex | 1.52188762 |
54 | MP0003111_abnormal_nucleus_morphology | 1.51955126 |
55 | MP0009643_abnormal_urine_homeostasis | 1.50809394 |
56 | MP0002938_white_spotting | 1.46574442 |
57 | MP0005266_abnormal_metabolism | 1.45941808 |
58 | MP0001765_abnormal_ion_homeostasis | 1.44753433 |
59 | MP0002249_abnormal_larynx_morphology | 1.44480272 |
60 | MP0002132_abnormal_respiratory_system | 1.44158675 |
61 | MP0010678_abnormal_skin_adnexa | 1.39291594 |
62 | MP0000372_irregular_coat_pigmentation | 1.38902800 |
63 | MP0005584_abnormal_enzyme/coenzyme_acti | 1.38630223 |
64 | MP0005075_abnormal_melanosome_morpholog | 1.37799685 |
65 | MP0005636_abnormal_mineral_homeostasis | 1.36690237 |
66 | MP0005408_hypopigmentation | 1.35056931 |
67 | MP0004019_abnormal_vitamin_homeostasis | 1.34171239 |
68 | MP0004147_increased_porphyrin_level | 1.31703716 |
69 | MP0001968_abnormal_touch/_nociception | 1.31412598 |
70 | MP0002837_dystrophic_cardiac_calcinosis | 1.31354095 |
71 | MP0003183_abnormal_peptide_metabolism | 1.31314321 |
72 | MP0003787_abnormal_imprinting | 1.29379740 |
73 | MP0001919_abnormal_reproductive_system | 1.28726139 |
74 | MP0001664_abnormal_digestion | 1.27529259 |
75 | MP0003763_abnormal_thymus_physiology | 1.24474952 |
76 | MP0009333_abnormal_splenocyte_physiolog | 1.24328757 |
77 | MP0000538_abnormal_urinary_bladder | 1.23396284 |
78 | MP0003724_increased_susceptibility_to | 1.22417444 |
79 | MP0003786_premature_aging | 1.20185485 |
80 | MP0003567_abnormal_fetal_cardiomyocyte | 1.19964739 |
81 | MP0003938_abnormal_ear_development | 1.19632128 |
82 | MP0000647_abnormal_sebaceous_gland | 1.19243133 |
83 | MP0005330_cardiomyopathy | 1.18986472 |
84 | MP0000609_abnormal_liver_physiology | 1.18697167 |
85 | MP0009785_altered_susceptibility_to | 1.18325568 |
86 | MP0002796_impaired_skin_barrier | 1.17657280 |
87 | MP0005551_abnormal_eye_electrophysiolog | 1.16802571 |
88 | MP0001545_abnormal_hematopoietic_system | 1.16696198 |
89 | MP0005397_hematopoietic_system_phenotyp | 1.16696198 |
90 | MP0003879_abnormal_hair_cell | 1.15703164 |
91 | MP0001502_abnormal_circadian_rhythm | 1.15543951 |
92 | MP0005645_abnormal_hypothalamus_physiol | 1.15275484 |
93 | MP0006292_abnormal_olfactory_placode | 1.13959606 |
94 | MP0005376_homeostasis/metabolism_phenot | 1.13609883 |
95 | MP0003195_calcinosis | 1.13273131 |
96 | MP0000358_abnormal_cell_content/ | 1.13223681 |
97 | MP0003936_abnormal_reproductive_system | 1.13219635 |
98 | MP0003011_delayed_dark_adaptation | 1.11651732 |
99 | MP0000678_abnormal_parathyroid_gland | 1.10866125 |
100 | MP0002118_abnormal_lipid_homeostasis | 1.08617218 |
101 | MP0003221_abnormal_cardiomyocyte_apopto | 1.07983043 |
102 | MP0001905_abnormal_dopamine_level | 1.07394830 |
103 | MP0005451_abnormal_body_composition | 1.06620611 |
104 | MP0001529_abnormal_vocalization | 1.06118953 |
105 | MP0008932_abnormal_embryonic_tissue | 1.05516091 |
106 | MP0010386_abnormal_urinary_bladder | 1.03383014 |
107 | MP0000566_synostosis | 1.02263276 |
108 | MP0008469_abnormal_protein_level | 1.01358907 |
109 | MP0005410_abnormal_fertilization | 0.99182818 |
110 | MP0009697_abnormal_copulation | 0.99017860 |
111 | MP0000026_abnormal_inner_ear | 0.97485785 |
112 | MP0001881_abnormal_mammary_gland | 0.97426381 |
113 | MP0002254_reproductive_system_inflammat | 0.97335983 |
114 | MP0008007_abnormal_cellular_replicative | 0.96875272 |
115 | MP0003866_abnormal_defecation | 0.96467216 |
116 | MP0000598_abnormal_liver_morphology | 0.93958261 |
117 | MP0001944_abnormal_pancreas_morphology | 0.93732606 |
118 | MP0001756_abnormal_urination | 0.90339055 |
119 | MP0002269_muscular_atrophy | 0.90179031 |
120 | MP0002019_abnormal_tumor_incidence | 0.86957255 |
121 | MP0006054_spinal_hemorrhage | 0.86941736 |
122 | MP0002163_abnormal_gland_morphology | 0.86428867 |
123 | MP0004782_abnormal_surfactant_physiolog | 0.85519628 |
124 | MP0005670_abnormal_white_adipose | 0.84938133 |
125 | MP0010155_abnormal_intestine_physiology | 0.84812305 |
126 | MP0005464_abnormal_platelet_physiology | 0.84686939 |
127 | MP0005501_abnormal_skin_physiology | 0.84418167 |
128 | MP0000470_abnormal_stomach_morphology | 0.83033125 |
129 | MP0003953_abnormal_hormone_level | 0.82997057 |
130 | MP0000689_abnormal_spleen_morphology | 0.82881631 |
131 | MP0005025_abnormal_response_to | 0.81812435 |
132 | MP0004215_abnormal_myocardial_fiber | 0.81546425 |
133 | MP0000613_abnormal_salivary_gland | 0.81522812 |
134 | MP0002102_abnormal_ear_morphology | 0.81390089 |
135 | MP0000749_muscle_degeneration | 0.80999385 |
136 | MP0005084_abnormal_gallbladder_morpholo | 0.80933975 |
137 | MP0004084_abnormal_cardiac_muscle | 0.80105927 |
138 | MP0008961_abnormal_basal_metabolism | 0.79854717 |
139 | MP0000631_abnormal_neuroendocrine_gland | 0.79812700 |
140 | MP0000467_abnormal_esophagus_morphology | 0.79620141 |
141 | MP0000627_abnormal_mammary_gland | 0.79536236 |
142 | MP0001730_embryonic_growth_arrest | 0.78546585 |
143 | MP0002722_abnormal_immune_system | 0.78422697 |
144 | MP0008872_abnormal_physiological_respon | 0.77651006 |
145 | MP0002693_abnormal_pancreas_physiology | 0.75518867 |
146 | MP0000049_abnormal_middle_ear | 0.75268311 |
147 | MP0002210_abnormal_sex_determination | 0.74976509 |
148 | MP0009642_abnormal_blood_homeostasis | 0.74538391 |
149 | MP0000685_abnormal_immune_system | 0.73497993 |
150 | MP0003942_abnormal_urinary_system | 0.71870966 |
151 | MP0000313_abnormal_cell_death | 0.71070278 |
152 | MP0002429_abnormal_blood_cell | 0.70970609 |
153 | MP0009763_increased_sensitivity_to | 0.70312474 |
154 | MP0000750_abnormal_muscle_regeneration | 0.69982819 |
155 | MP0004036_abnormal_muscle_relaxation | 0.69777932 |
156 | MP0002398_abnormal_bone_marrow | 0.69435399 |
157 | MP0008873_increased_physiological_sensi | 0.67305837 |
158 | MP0000747_muscle_weakness | 0.66117435 |
159 | MP0001845_abnormal_inflammatory_respons | 0.65237162 |
160 | MP0001835_abnormal_antigen_presentation | 0.65153166 |
161 | MP0003436_decreased_susceptibility_to | 0.63721822 |
162 | MP0000858_altered_metastatic_potential | 0.63576559 |
163 | MP0001544_abnormal_cardiovascular_syste | 0.63218066 |
164 | MP0005385_cardiovascular_system_phenoty | 0.63218066 |
165 | MP0004808_abnormal_hematopoietic_stem | 0.62551016 |
166 | MP0004264_abnormal_extraembryonic_tissu | 0.61755716 |
167 | MP0002136_abnormal_kidney_physiology | 0.60913318 |
168 | MP0001663_abnormal_digestive_system | 0.60401623 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Respiratory insufficiency due to defective ciliary clearance (HP:0200073) | 5.24638472 |
2 | Hepatic necrosis (HP:0002605) | 5.14231912 |
3 | Hepatocellular necrosis (HP:0001404) | 4.97471337 |
4 | Abnormality of cells of the erythroid lineage (HP:0012130) | 4.74540874 |
5 | Abnormal number of erythroid precursors (HP:0012131) | 4.53236854 |
6 | Mitochondrial inheritance (HP:0001427) | 4.45683609 |
7 | Acute necrotizing encephalopathy (HP:0006965) | 4.44120982 |
8 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 4.40183171 |
9 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 4.40183171 |
10 | Abnormal mitochondria in muscle tissue (HP:0008316) | 4.31485781 |
11 | Abnormal respiratory motile cilium physiology (HP:0012261) | 4.30727123 |
12 | Abnormal respiratory motile cilium morphology (HP:0005938) | 4.28587874 |
13 | Abnormal respiratory epithelium morphology (HP:0012253) | 4.28587874 |
14 | Acute encephalopathy (HP:0006846) | 4.27502304 |
15 | Increased CSF lactate (HP:0002490) | 4.19029150 |
16 | Absent/shortened dynein arms (HP:0200106) | 4.01668891 |
17 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 4.01668891 |
18 | Chronic bronchitis (HP:0004469) | 3.86073183 |
19 | Abnormal ciliary motility (HP:0012262) | 3.79067291 |
20 | Rhinitis (HP:0012384) | 3.73761560 |
21 | Cerebral edema (HP:0002181) | 3.72788154 |
22 | Lactic acidosis (HP:0003128) | 3.69149599 |
23 | Increased serum lactate (HP:0002151) | 3.65095899 |
24 | Lipid accumulation in hepatocytes (HP:0006561) | 3.60585210 |
25 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 3.58259915 |
26 | Increased muscle lipid content (HP:0009058) | 3.57518926 |
27 | Reticulocytopenia (HP:0001896) | 3.56351420 |
28 | Increased intramyocellular lipid droplets (HP:0012240) | 3.52299745 |
29 | Abnormality of dicarboxylic acid metabolism (HP:0010995) | 3.52076396 |
30 | Dicarboxylic aciduria (HP:0003215) | 3.52076396 |
31 | Increased hepatocellular lipid droplets (HP:0006565) | 3.45785431 |
32 | Progressive macrocephaly (HP:0004481) | 3.45265329 |
33 | Concave nail (HP:0001598) | 3.35579290 |
34 | Abnormality of aromatic amino acid family metabolism (HP:0004338) | 3.28705128 |
35 | Abnormality of fatty-acid metabolism (HP:0004359) | 3.24482542 |
36 | Lethargy (HP:0001254) | 3.14552861 |
37 | Generalized aminoaciduria (HP:0002909) | 3.14072312 |
38 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 3.11510620 |
39 | Pancreatic cysts (HP:0001737) | 3.09659724 |
40 | Chronic hepatic failure (HP:0100626) | 3.09136415 |
41 | Hyperammonemia (HP:0001987) | 3.04741275 |
42 | Macrocytic anemia (HP:0001972) | 3.04632190 |
43 | True hermaphroditism (HP:0010459) | 3.03319381 |
44 | 3-Methylglutaconic aciduria (HP:0003535) | 3.02797771 |
45 | Aplastic anemia (HP:0001915) | 3.01995447 |
46 | Hyperglycinuria (HP:0003108) | 3.01812587 |
47 | Respiratory failure (HP:0002878) | 2.93530059 |
48 | Renal Fanconi syndrome (HP:0001994) | 2.93373611 |
49 | Exercise intolerance (HP:0003546) | 2.91928374 |
50 | Oral leukoplakia (HP:0002745) | 2.88839606 |
51 | Abnormality of glycolysis (HP:0004366) | 2.86932709 |
52 | Increased serum pyruvate (HP:0003542) | 2.86932709 |
53 | Tubular atrophy (HP:0000092) | 2.86259678 |
54 | Pancreatic fibrosis (HP:0100732) | 2.86216306 |
55 | Birth length less than 3rd percentile (HP:0003561) | 2.83562534 |
56 | Hyperglycinemia (HP:0002154) | 2.83071416 |
57 | Abnormality of glycine metabolism (HP:0010895) | 2.78397632 |
58 | Abnormality of serine family amino acid metabolism (HP:0010894) | 2.78397632 |
59 | CNS demyelination (HP:0007305) | 2.76669037 |
60 | Vascular calcification (HP:0004934) | 2.75777545 |
61 | Abnormality of midbrain morphology (HP:0002418) | 2.74251105 |
62 | Molar tooth sign on MRI (HP:0002419) | 2.74251105 |
63 | Respiratory difficulties (HP:0002880) | 2.67795689 |
64 | Large for gestational age (HP:0001520) | 2.66847095 |
65 | Type I transferrin isoform profile (HP:0003642) | 2.63229950 |
66 | Multiple enchondromatosis (HP:0005701) | 2.60273805 |
67 | Ragged-red muscle fibers (HP:0003200) | 2.59850241 |
68 | Nephronophthisis (HP:0000090) | 2.59736932 |
69 | Rhabdomyolysis (HP:0003201) | 2.59232598 |
70 | Hypobetalipoproteinemia (HP:0003563) | 2.58942401 |
71 | Exertional dyspnea (HP:0002875) | 2.58503212 |
72 | Cystic liver disease (HP:0006706) | 2.55646594 |
73 | Hypoglycemic coma (HP:0001325) | 2.54688495 |
74 | Reduced antithrombin III activity (HP:0001976) | 2.53707364 |
75 | Bronchiectasis (HP:0002110) | 2.51427197 |
76 | Nausea (HP:0002018) | 2.50310243 |
77 | Ketosis (HP:0001946) | 2.49240298 |
78 | Abnormality of long-chain fatty-acid metabolism (HP:0010964) | 2.47574806 |
79 | Abnormality of monocarboxylic acid metabolism (HP:0010996) | 2.47210849 |
80 | Abnormality of pyrimidine metabolism (HP:0004353) | 2.47120483 |
81 | Pallor (HP:0000980) | 2.46685581 |
82 | Abnormality of urine glucose concentration (HP:0011016) | 2.46477466 |
83 | Glycosuria (HP:0003076) | 2.46477466 |
84 | Methylmalonic aciduria (HP:0012120) | 2.45349335 |
85 | Occipital encephalocele (HP:0002085) | 2.43911108 |
86 | Metabolic acidosis (HP:0001942) | 2.40492173 |
87 | Thrombocytosis (HP:0001894) | 2.39863560 |
88 | Abnormality of serum amino acid levels (HP:0003112) | 2.36834944 |
89 | Abnormality of the heme biosynthetic pathway (HP:0010472) | 2.32871669 |
90 | Emotional lability (HP:0000712) | 2.32200925 |
91 | Vomiting (HP:0002013) | 2.31151154 |
92 | Pancytopenia (HP:0001876) | 2.31020839 |
93 | Palpitations (HP:0001962) | 2.30408010 |
94 | Tubulointerstitial nephritis (HP:0001970) | 2.27988218 |
95 | Microvesicular hepatic steatosis (HP:0001414) | 2.26676658 |
96 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 2.26116455 |
97 | Abnormality of alanine metabolism (HP:0010916) | 2.25485768 |
98 | Hyperalaninemia (HP:0003348) | 2.25485768 |
99 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 2.25485768 |
100 | Proximal tubulopathy (HP:0000114) | 2.24427978 |
101 | Pendular nystagmus (HP:0012043) | 2.22179509 |
102 | Hyperlipoproteinemia (HP:0010980) | 2.13794521 |
103 | Progressive muscle weakness (HP:0003323) | 2.11678370 |
104 | Abnormality of the renal medulla (HP:0100957) | 2.11070056 |
105 | Cardiovascular calcification (HP:0011915) | 2.09095584 |
106 | Male pseudohermaphroditism (HP:0000037) | 2.09017273 |
107 | Hyperphosphatemia (HP:0002905) | 2.07735522 |
108 | Hyperthyroidism (HP:0000836) | 2.07521699 |
109 | Decreased circulating renin level (HP:0003351) | 2.07518463 |
110 | Hyperactive renin-angiotensin system (HP:0000841) | 2.07173255 |
111 | Sclerocornea (HP:0000647) | 2.06314331 |
112 | Intrahepatic cholestasis (HP:0001406) | 2.05802454 |
113 | Myoglobinuria (HP:0002913) | 2.03863838 |
114 | Microretrognathia (HP:0000308) | 2.03827019 |
115 | Petechiae (HP:0000967) | 2.03582954 |
116 | Aplasia/hypoplasia of the uterus (HP:0008684) | 2.03492754 |
117 | Abnormal rod and cone electroretinograms (HP:0008323) | 2.00723239 |
118 | Testicular atrophy (HP:0000029) | 2.00600921 |
119 | Abnormal urine phosphate concentration (HP:0012599) | 1.98606802 |
120 | Gliosis (HP:0002171) | 1.97587857 |
121 | Ketoacidosis (HP:0001993) | 1.97321595 |
122 | Abnormality of renal resorption (HP:0011038) | 1.97235814 |
123 | Leukodystrophy (HP:0002415) | 1.96918745 |
124 | Optic disc pallor (HP:0000543) | 1.94650832 |
125 | Type II lissencephaly (HP:0007260) | 1.93960596 |
126 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 1.93192230 |
127 | Abnormal protein N-linked glycosylation (HP:0012347) | 1.93192230 |
128 | Abnormal protein glycosylation (HP:0012346) | 1.93192230 |
129 | Abnormal glycosylation (HP:0012345) | 1.93192230 |
130 | Methylmalonic acidemia (HP:0002912) | 1.92632895 |
131 | Cerebral hypomyelination (HP:0006808) | 1.92329417 |
132 | Amelogenesis imperfecta (HP:0000705) | 1.91968099 |
133 | Gout (HP:0001997) | 1.91717180 |
134 | Polydipsia (HP:0001959) | 1.91190265 |
135 | Abnormal drinking behavior (HP:0030082) | 1.91190265 |
136 | Pili torti (HP:0003777) | 1.90470924 |
137 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 1.90202157 |
138 | Rough bone trabeculation (HP:0100670) | 1.89585455 |
139 | Furrowed tongue (HP:0000221) | 1.88956014 |
140 | Hyperbilirubinemia (HP:0002904) | 1.88946307 |
141 | Megaloblastic anemia (HP:0001889) | 1.88644615 |
142 | Abnormality of renal excretion (HP:0011036) | 1.88528707 |
143 | Sparse eyelashes (HP:0000653) | 1.88205431 |
144 | Abnormality of magnesium homeostasis (HP:0004921) | 1.86859582 |
145 | IgM deficiency (HP:0002850) | 1.86673521 |
146 | Delayed CNS myelination (HP:0002188) | 1.86228102 |
147 | Spastic paraparesis (HP:0002313) | 1.83634495 |
148 | Abnormality of methionine metabolism (HP:0010901) | 1.82497975 |
149 | Hypoplasia of the uterus (HP:0000013) | 1.81504837 |
150 | Aplasia/Hypoplasia of the tongue (HP:0010295) | 1.80030373 |
151 | Congenital stationary night blindness (HP:0007642) | 1.75214168 |
152 | Abnormality of the renal cortex (HP:0011035) | 1.73684330 |
153 | Septate vagina (HP:0001153) | 1.73659549 |
154 | Hypomagnesemia (HP:0002917) | 1.71226843 |
155 | Hypokinesia (HP:0002375) | 1.71140804 |
Rank | Gene Set | Z-score |
---|---|---|
1 | BCKDK | 4.39053982 |
2 | NME2 | 4.11594850 |
3 | STK16 | 3.60381927 |
4 | WEE1 | 3.55524659 |
5 | EIF2AK1 | 3.22171262 |
6 | BUB1 | 3.02192845 |
7 | MAPK15 | 2.76939345 |
8 | PIM2 | 2.72836158 |
9 | VRK2 | 2.71968260 |
10 | EIF2AK3 | 2.36517040 |
11 | NME1 | 2.33425663 |
12 | MST1R | 2.14432083 |
13 | VRK1 | 2.08735304 |
14 | MYLK | 2.02388459 |
15 | TRIB3 | 2.00914848 |
16 | GRK1 | 1.98674935 |
17 | FLT3 | 1.93500670 |
18 | FRK | 1.73375164 |
19 | PDK4 | 1.72088801 |
20 | PDK3 | 1.72088801 |
21 | KDR | 1.69089867 |
22 | WNK4 | 1.63511026 |
23 | MAP3K12 | 1.61677654 |
24 | NUAK1 | 1.61022280 |
25 | RPS6KB2 | 1.50238998 |
26 | MAP3K11 | 1.49829027 |
27 | MUSK | 1.47678175 |
28 | SRPK1 | 1.45024885 |
29 | MAP4K1 | 1.41781182 |
30 | TEC | 1.41231026 |
31 | ACVR1B | 1.40964863 |
32 | TSSK6 | 1.39975098 |
33 | PDK2 | 1.39805407 |
34 | TRIM28 | 1.37380629 |
35 | MAP2K3 | 1.37167260 |
36 | SIK1 | 1.37054593 |
37 | BRSK2 | 1.36669814 |
38 | TESK2 | 1.36664272 |
39 | MAPKAPK3 | 1.34483650 |
40 | ERN1 | 1.33944811 |
41 | PKN2 | 1.32355722 |
42 | STK39 | 1.32100768 |
43 | MAP2K7 | 1.31705745 |
44 | EPHA2 | 1.26772149 |
45 | MAP4K2 | 1.26350647 |
46 | ZAK | 1.22795973 |
47 | NEK1 | 1.21510123 |
48 | TESK1 | 1.17284610 |
49 | DYRK3 | 1.16443501 |
50 | MAP2K6 | 1.14699279 |
51 | LRRK2 | 1.13717195 |
52 | TGFBR1 | 1.12743575 |
53 | ZAP70 | 1.10256288 |
54 | MST4 | 1.10132379 |
55 | BTK | 1.06397649 |
56 | CDK7 | 1.02215177 |
57 | CDC7 | 1.00253567 |
58 | KIT | 0.99517625 |
59 | ARAF | 0.99264848 |
60 | BMPR1B | 0.97960815 |
61 | PLK4 | 0.96689816 |
62 | PTK6 | 0.95313149 |
63 | TLK1 | 0.95044816 |
64 | PHKG2 | 0.94738578 |
65 | PHKG1 | 0.94738578 |
66 | PIK3CA | 0.91685425 |
67 | ILK | 0.89818706 |
68 | PRKD3 | 0.85297388 |
69 | OBSCN | 0.84314164 |
70 | CDK8 | 0.81761261 |
71 | ABL2 | 0.80653286 |
72 | NEK6 | 0.80140994 |
73 | NEK2 | 0.78719220 |
74 | AURKB | 0.78453955 |
75 | EIF2AK2 | 0.77707504 |
76 | CDK4 | 0.76502014 |
77 | SMG1 | 0.75588320 |
78 | MAP2K2 | 0.75525915 |
79 | AURKA | 0.75454726 |
80 | CAMK2D | 0.74101528 |
81 | IRAK3 | 0.72005224 |
82 | PLK1 | 0.71993176 |
83 | OXSR1 | 0.69927801 |
84 | INSRR | 0.69668450 |
85 | MAPK4 | 0.69263014 |
86 | CSNK2A2 | 0.69249636 |
87 | MAP3K3 | 0.69175501 |
88 | TAOK2 | 0.68513250 |
89 | PIM1 | 0.67976983 |
90 | CSNK2A1 | 0.67482481 |
91 | PAK4 | 0.67135819 |
92 | BRAF | 0.66299151 |
93 | ADRBK1 | 0.66156927 |
94 | PINK1 | 0.64919910 |
95 | ATR | 0.62522521 |
96 | CCNB1 | 0.61860312 |
97 | SIK3 | 0.61844691 |
98 | CAMK2G | 0.61688739 |
99 | GRK6 | 0.61008846 |
100 | WNK3 | 0.60532668 |
101 | CHUK | 0.60047413 |
102 | TNK2 | 0.59410681 |
103 | FER | 0.58893359 |
104 | MAP3K8 | 0.58638444 |
105 | TTK | 0.57525460 |
106 | TAOK1 | 0.56206756 |
107 | TIE1 | 0.55247195 |
108 | AKT2 | 0.54076857 |
109 | RPS6KA4 | 0.53768885 |
110 | TBK1 | 0.53675095 |
111 | RAF1 | 0.53384103 |
112 | PRKD2 | 0.53093152 |
113 | MAP2K1 | 0.51930779 |
114 | DAPK1 | 0.51632394 |
115 | BRSK1 | 0.51458424 |
116 | CDK19 | 0.51128291 |
117 | TYK2 | 0.50558678 |
118 | SYK | 0.50509270 |
119 | LMTK2 | 0.50248295 |
120 | CSNK1A1 | 0.50159252 |
121 | MATK | 0.48532627 |
122 | PRKCI | 0.48014848 |
123 | STK38L | 0.47736271 |
124 | RPS6KA5 | 0.47480756 |
125 | MAPKAPK2 | 0.47188882 |
126 | MET | 0.46216048 |
127 | DYRK2 | 0.45316264 |
128 | IRAK4 | 0.44268394 |
129 | SCYL2 | 0.43598611 |
130 | PRKG2 | 0.43235091 |
131 | PAK3 | 0.43151981 |
132 | TAOK3 | 0.42687824 |
133 | IKBKB | 0.42685436 |
134 | NLK | 0.42669030 |
135 | LIMK1 | 0.42551764 |
136 | STK24 | 0.40492152 |
137 | RPS6KA6 | 0.39525397 |
138 | DAPK3 | 0.38983964 |
139 | MAP3K6 | 0.37396857 |
140 | MAPK13 | 0.37378305 |
141 | PAK1 | 0.36916814 |
142 | CSNK1G3 | 0.36535693 |
143 | MKNK1 | 0.36227463 |
144 | LYN | 0.34223765 |
145 | ADRBK2 | 0.33818695 |
146 | PRKCE | 0.33527780 |
147 | RPS6KA2 | 0.33403924 |
148 | TXK | 0.32996582 |
149 | PBK | 0.32377146 |
150 | PRKCZ | 0.31877079 |
151 | MAPKAPK5 | 0.26777998 |
152 | PRKCD | 0.26549332 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Ribosome_Homo sapiens_hsa03010 | 3.81914052 |
2 | Proteasome_Homo sapiens_hsa03050 | 2.95449176 |
3 | DNA replication_Homo sapiens_hsa03030 | 2.87856262 |
4 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 2.63364568 |
5 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 2.50818117 |
6 | Parkinsons disease_Homo sapiens_hsa05012 | 2.49183471 |
7 | RNA polymerase_Homo sapiens_hsa03020 | 2.34866058 |
8 | Mismatch repair_Homo sapiens_hsa03430 | 2.18272787 |
9 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 2.16084662 |
10 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 2.13447274 |
11 | Caffeine metabolism_Homo sapiens_hsa00232 | 2.08684739 |
12 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 2.06705380 |
13 | Propanoate metabolism_Homo sapiens_hsa00640 | 2.00287405 |
14 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 1.97925087 |
15 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.85722495 |
16 | Folate biosynthesis_Homo sapiens_hsa00790 | 1.84937461 |
17 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 1.77796588 |
18 | Huntingtons disease_Homo sapiens_hsa05016 | 1.76519944 |
19 | Fatty acid degradation_Homo sapiens_hsa00071 | 1.74413228 |
20 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.72785754 |
21 | Carbon metabolism_Homo sapiens_hsa01200 | 1.72173230 |
22 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 1.71716693 |
23 | Base excision repair_Homo sapiens_hsa03410 | 1.71574541 |
24 | Sulfur relay system_Homo sapiens_hsa04122 | 1.68036928 |
25 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.66883737 |
26 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.64456616 |
27 | Pyruvate metabolism_Homo sapiens_hsa00620 | 1.56982623 |
28 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 1.54697496 |
29 | Alzheimers disease_Homo sapiens_hsa05010 | 1.52624944 |
30 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 1.51041328 |
31 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.49259533 |
32 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 1.47677610 |
33 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 1.47276717 |
34 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 1.44502164 |
35 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 1.42014364 |
36 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.41922341 |
37 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.40561065 |
38 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 1.39792247 |
39 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.38837997 |
40 | Homologous recombination_Homo sapiens_hsa03440 | 1.38512100 |
41 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 1.37860243 |
42 | Peroxisome_Homo sapiens_hsa04146 | 1.37720116 |
43 | Spliceosome_Homo sapiens_hsa03040 | 1.35198662 |
44 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 1.34830721 |
45 | Glutathione metabolism_Homo sapiens_hsa00480 | 1.33518145 |
46 | Protein export_Homo sapiens_hsa03060 | 1.33124231 |
47 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 1.31192469 |
48 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 1.30761578 |
49 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 1.29809746 |
50 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 1.23007202 |
51 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 1.22511982 |
52 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 1.21654053 |
53 | Fatty acid elongation_Homo sapiens_hsa00062 | 1.21335734 |
54 | Selenocompound metabolism_Homo sapiens_hsa00450 | 1.19575020 |
55 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 1.18867753 |
56 | RNA transport_Homo sapiens_hsa03013 | 1.13178884 |
57 | Fatty acid metabolism_Homo sapiens_hsa01212 | 1.10874246 |
58 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 1.10482791 |
59 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 1.08629170 |
60 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 1.07650421 |
61 | Tryptophan metabolism_Homo sapiens_hsa00380 | 1.06846359 |
62 | Purine metabolism_Homo sapiens_hsa00230 | 1.06218782 |
63 | Galactose metabolism_Homo sapiens_hsa00052 | 1.05215164 |
64 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.02690074 |
65 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.02378162 |
66 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 1.00282796 |
67 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.98677992 |
68 | Mineral absorption_Homo sapiens_hsa04978 | 0.97444247 |
69 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.95558040 |
70 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.95229139 |
71 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.94996753 |
72 | Phototransduction_Homo sapiens_hsa04744 | 0.94711091 |
73 | Metabolic pathways_Homo sapiens_hsa01100 | 0.93936014 |
74 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.90571134 |
75 | Histidine metabolism_Homo sapiens_hsa00340 | 0.88132247 |
76 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.84992238 |
77 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 0.83913425 |
78 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.82113884 |
79 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.79623331 |
80 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 0.75919521 |
81 | RNA degradation_Homo sapiens_hsa03018 | 0.75320369 |
82 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.74617248 |
83 | Tight junction_Homo sapiens_hsa04530 | 0.74286541 |
84 | PPAR signaling pathway_Homo sapiens_hsa03320 | 0.71620509 |
85 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 0.71265242 |
86 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 0.70263812 |
87 | Basal transcription factors_Homo sapiens_hsa03022 | 0.67169165 |
88 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.66823654 |
89 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 0.65229750 |
90 | Arginine biosynthesis_Homo sapiens_hsa00220 | 0.64770501 |
91 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.63918757 |
92 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.62836287 |
93 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.60582543 |
94 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.57155345 |
95 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.56135811 |
96 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.53693359 |
97 | Retinol metabolism_Homo sapiens_hsa00830 | 0.51105258 |
98 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.50198437 |
99 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.44363820 |
100 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.42807243 |
101 | Cell cycle_Homo sapiens_hsa04110 | 0.42767837 |
102 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.42112197 |
103 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.40519958 |
104 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.40205614 |
105 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.39703157 |
106 | Taste transduction_Homo sapiens_hsa04742 | 0.37588112 |
107 | Olfactory transduction_Homo sapiens_hsa04740 | 0.34637220 |
108 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.33533702 |
109 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.32273434 |
110 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.31888107 |
111 | Complement and coagulation cascades_Homo sapiens_hsa04610 | 0.30770480 |
112 | Other glycan degradation_Homo sapiens_hsa00511 | 0.27433122 |
113 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.26834571 |
114 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.26780486 |
115 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.24878424 |
116 | Thyroid cancer_Homo sapiens_hsa05216 | 0.23490173 |
117 | Renin-angiotensin system_Homo sapiens_hsa04614 | 0.22329544 |
118 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.19955013 |
119 | ABC transporters_Homo sapiens_hsa02010 | 0.17827824 |