ABHD14A

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1ribosomal small subunit assembly (GO:0000028)6.48467303
2DNA deamination (GO:0045006)5.91753732
3viral transcription (GO:0019083)5.37970399
4ribosomal small subunit biogenesis (GO:0042274)5.22613258
5translational termination (GO:0006415)5.19691892
6mitochondrial ATP synthesis coupled proton transport (GO:0042776)5.11440093
7SRP-dependent cotranslational protein targeting to membrane (GO:0006614)4.96148574
8cotranslational protein targeting to membrane (GO:0006613)4.92700576
9protein targeting to ER (GO:0045047)4.85071320
10ATP synthesis coupled proton transport (GO:0015986)4.78544318
11energy coupled proton transport, down electrochemical gradient (GO:0015985)4.78544318
12NADH dehydrogenase complex assembly (GO:0010257)4.75871802
13mitochondrial respiratory chain complex I biogenesis (GO:0097031)4.75871802
14mitochondrial respiratory chain complex I assembly (GO:0032981)4.75871802
15translational elongation (GO:0006414)4.71651746
16protein localization to endoplasmic reticulum (GO:0070972)4.66171052
17establishment of protein localization to endoplasmic reticulum (GO:0072599)4.56884359
18L-methionine biosynthetic process from methylthioadenosine (GO:0019509)4.55597248
19maturation of SSU-rRNA (GO:0030490)4.51776921
20protein complex biogenesis (GO:0070271)4.51071668
21pyrimidine nucleobase catabolic process (GO:0006208)4.46349959
22chaperone-mediated protein transport (GO:0072321)4.44853105
23mitochondrial respiratory chain complex assembly (GO:0033108)4.32200728
24behavioral response to nicotine (GO:0035095)4.29544887
25pseudouridine synthesis (GO:0001522)4.23422735
26GTP biosynthetic process (GO:0006183)4.22069868
27cellular protein complex disassembly (GO:0043624)4.17859732
28viral life cycle (GO:0019058)4.13269218
29oxidative phosphorylation (GO:0006119)4.07924831
30respiratory chain complex IV assembly (GO:0008535)4.07132233
31establishment of integrated proviral latency (GO:0075713)4.03531523
32DNA strand elongation involved in DNA replication (GO:0006271)3.99664135
33termination of RNA polymerase III transcription (GO:0006386)3.95773396
34transcription elongation from RNA polymerase III promoter (GO:0006385)3.95773396
35telomere maintenance via semi-conservative replication (GO:0032201)3.95200035
36translational initiation (GO:0006413)3.95079417
37nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)3.94185958
38guanosine-containing compound biosynthetic process (GO:1901070)3.91263412
39UTP biosynthetic process (GO:0006228)3.88896497
40translation (GO:0006412)3.85445507
41cullin deneddylation (GO:0010388)3.83811706
42DNA strand elongation (GO:0022616)3.82467723
43protein deneddylation (GO:0000338)3.77285761
44ribosomal large subunit biogenesis (GO:0042273)3.75363236
45synaptic vesicle maturation (GO:0016188)3.71922326
46mitochondrial electron transport, NADH to ubiquinone (GO:0006120)3.71392946
47respiratory electron transport chain (GO:0022904)3.71177891
48electron transport chain (GO:0022900)3.67523003
49proteasome assembly (GO:0043248)3.66872962
50nucleobase catabolic process (GO:0046113)3.66419944
51CTP metabolic process (GO:0046036)3.65145915
52CTP biosynthetic process (GO:0006241)3.65145915
53protein complex disassembly (GO:0043241)3.63860418
54deoxyribonucleoside monophosphate metabolic process (GO:0009162)3.61780696
55UTP metabolic process (GO:0046051)3.57374818
56cellular component biogenesis (GO:0044085)3.56704695
57ribonucleoprotein complex biogenesis (GO:0022613)3.50416315
58macromolecular complex disassembly (GO:0032984)3.49587084
59protein targeting to mitochondrion (GO:0006626)3.48812985
60pyrimidine nucleoside triphosphate metabolic process (GO:0009147)3.48315347
61positive regulation of mitochondrial fission (GO:0090141)3.47579184
62synaptic vesicle exocytosis (GO:0016079)3.45177020
63pyrimidine ribonucleoside triphosphate biosynthetic process (GO:0009209)3.44613706
64positive regulation of calcium ion-dependent exocytosis (GO:0045956)3.43207397
65DNA replication initiation (GO:0006270)3.41795405
66pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148)3.41438146
67tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)3.41272677
68RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)3.41272677
69metallo-sulfur cluster assembly (GO:0031163)3.40919503
70iron-sulfur cluster assembly (GO:0016226)3.40919503
71negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)3.40544149
72regulation of short-term neuronal synaptic plasticity (GO:0048172)3.38726489
73postsynaptic membrane organization (GO:0001941)3.35113196
74establishment of protein localization to mitochondrion (GO:0072655)3.31646814
75cytochrome complex assembly (GO:0017004)3.31086471
76regulation of cellular amino acid metabolic process (GO:0006521)3.30804239
77platelet dense granule organization (GO:0060155)3.30292912
78formation of translation preinitiation complex (GO:0001731)3.29765857
79L-methionine salvage (GO:0071267)3.28264733
80L-methionine biosynthetic process (GO:0071265)3.28264733
81amino acid salvage (GO:0043102)3.28264733
82establishment of mitochondrion localization (GO:0051654)3.27789903
83protein localization to synapse (GO:0035418)3.27371788
84peptidyl-histidine modification (GO:0018202)3.27066991
85nucleobase biosynthetic process (GO:0046112)3.26953341
86mannosylation (GO:0097502)3.26548615
87pyrimidine deoxyribonucleotide catabolic process (GO:0009223)3.24539429
88pyrimidine ribonucleoside triphosphate metabolic process (GO:0009208)3.23740121
89protein targeting to membrane (GO:0006612)3.22684324
90neuron cell-cell adhesion (GO:0007158)3.20380513
91nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)3.20066198
92negative regulation of ubiquitin-protein transferase activity (GO:0051444)3.19403447
93negative regulation of ligase activity (GO:0051352)3.19403447
94exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 3.18797118
95establishment of viral latency (GO:0019043)3.18657620
96ubiquinone biosynthetic process (GO:0006744)3.15234939
97rRNA processing (GO:0006364)3.13593263
98aerobic respiration (GO:0009060)3.13084442
99protein neddylation (GO:0045116)3.12763088
100negative regulation of telomere maintenance (GO:0032205)3.12631129
101purine ribonucleoside triphosphate biosynthetic process (GO:0009206)3.12310972
102telomere maintenance via recombination (GO:0000722)3.11816436
103protein localization to cilium (GO:0061512)3.11597676
104purine nucleoside triphosphate biosynthetic process (GO:0009145)3.10933183
105DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:003.10791704
106GDP-mannose metabolic process (GO:0019673)3.08062053
107gamma-aminobutyric acid transport (GO:0015812)3.07280524
108regulation of cilium movement (GO:0003352)3.05529124
109inner mitochondrial membrane organization (GO:0007007)3.04857790
110hydrogen ion transmembrane transport (GO:1902600)3.04760662
111positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)3.04664900
112establishment of protein localization to mitochondrial membrane (GO:0090151)3.04406516
113signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)3.03265060
114intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)3.03265060
115viral mRNA export from host cell nucleus (GO:0046784)3.02542650
116regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)3.02226076
117GMP metabolic process (GO:0046037)3.01386179
118spliceosomal snRNP assembly (GO:0000387)3.00278150
119ubiquinone metabolic process (GO:0006743)2.97548835
120synaptic transmission, glutamatergic (GO:0035249)2.96160708
121regulation of mitochondrial translation (GO:0070129)2.94209729
122energy coupled proton transmembrane transport, against electrochemical gradient (GO:0015988)2.93786248
123ATP hydrolysis coupled proton transport (GO:0015991)2.93786248
124sequestering of actin monomers (GO:0042989)2.92267181
125regulation of inhibitory postsynaptic membrane potential (GO:0060080)2.89272473
126ATP biosynthetic process (GO:0006754)2.86931195
127membrane depolarization during cardiac muscle cell action potential (GO:0086012)2.86145446
128proton transport (GO:0015992)2.85638702
129hydrogen transport (GO:0006818)2.82458187
130dendritic spine morphogenesis (GO:0060997)2.80231127
131negative regulation of synaptic transmission, GABAergic (GO:0032229)2.80156150
132transmission of nerve impulse (GO:0019226)2.78035242
133preassembly of GPI anchor in ER membrane (GO:0016254)2.75796530
134neurotransmitter-gated ion channel clustering (GO:0072578)2.74791149
135neurotransmitter secretion (GO:0007269)2.73497874
136positive regulation of amino acid transport (GO:0051957)2.72530491
137glutamate secretion (GO:0014047)2.72477384
138protein-cofactor linkage (GO:0018065)2.71507777
139regulation of synapse structural plasticity (GO:0051823)2.69657149
140neuronal action potential propagation (GO:0019227)2.67801849
141protein polyglutamylation (GO:0018095)2.67558130
142nonmotile primary cilium assembly (GO:0035058)2.64642713
143positive regulation of TOR signaling (GO:0032008)2.61686958
144neuromuscular synaptic transmission (GO:0007274)2.61375840
145regulation of synaptic vesicle exocytosis (GO:2000300)2.60293851
146GPI anchor metabolic process (GO:0006505)2.56529096
147neuron-neuron synaptic transmission (GO:0007270)2.55844223
148water-soluble vitamin biosynthetic process (GO:0042364)2.55731298
149C-terminal protein lipidation (GO:0006501)2.54174197
150G-protein coupled glutamate receptor signaling pathway (GO:0007216)2.54026007
151establishment of mitochondrion localization, microtubule-mediated (GO:0034643)2.53937320
152mitochondrion transport along microtubule (GO:0047497)2.53937320
153epithelial cilium movement (GO:0003351)2.53140710
154opioid receptor signaling pathway (GO:0038003)2.52663641
155retinal ganglion cell axon guidance (GO:0031290)2.52520266
156regulation of synaptic vesicle transport (GO:1902803)2.51261991
157GPI anchor biosynthetic process (GO:0006506)2.49178372
158regulation of feeding behavior (GO:0060259)2.47943445
159glycosphingolipid biosynthetic process (GO:0006688)2.46826098
160neurofilament cytoskeleton organization (GO:0060052)2.45847495
161axoneme assembly (GO:0035082)2.45720600
162auditory behavior (GO:0031223)2.45616522
163quinone biosynthetic process (GO:1901663)2.45120708
164aggressive behavior (GO:0002118)2.44708715
165regulation of neurotransmitter levels (GO:0001505)2.41791849
166C4-dicarboxylate transport (GO:0015740)2.40161418
167synaptic transmission, cholinergic (GO:0007271)2.39686782
168C-terminal protein amino acid modification (GO:0018410)2.38310700
169ribonucleoside triphosphate biosynthetic process (GO:0009201)2.38215954

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human4.83468625
2MYC_18555785_ChIP-Seq_MESCs_Mouse4.55336836
3EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse4.28703807
4NOTCH1_17114293_ChIP-ChIP_T-ALL_Human4.26339421
5KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human4.12078586
6E2F7_22180533_ChIP-Seq_HELA_Human4.07179682
7JARID1A_20064375_ChIP-Seq_MESCs_Mouse3.98111047
8GABP_17652178_ChIP-ChIP_JURKAT_Human3.93288249
9EST1_17652178_ChIP-ChIP_JURKAT_Human3.89156138
10HCFC1_20581084_ChIP-Seq_MESCs_Mouse3.88577747
11NR4A2_19515692_ChIP-ChIP_MN9D_Mouse3.72154490
12SOX9_22984422_ChIP-ChIP_TESTIS_Rat3.66494200
13ETS1_20019798_ChIP-Seq_JURKAT_Human3.46880020
14* MYC_18358816_ChIP-ChIP_MESCs_Mouse3.42702974
15HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human3.05878699
16ELF1_17652178_ChIP-ChIP_JURKAT_Human2.98184491
17ZNF274_21170338_ChIP-Seq_K562_Hela2.93651748
18CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.91343918
19CREB1_15753290_ChIP-ChIP_HEK293T_Human2.89145332
20MYC_19030024_ChIP-ChIP_MESCs_Mouse2.82654014
21MYC_19079543_ChIP-ChIP_MESCs_Mouse2.68405260
22* SRF_21415370_ChIP-Seq_HL-1_Mouse2.63726412
23THAP11_20581084_ChIP-Seq_MESCs_Mouse2.57871663
24CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons2.51173129
25VDR_23849224_ChIP-Seq_CD4+_Human2.46243021
26CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.45682561
27YY1_21170310_ChIP-Seq_MESCs_Mouse2.44088157
28XRN2_22483619_ChIP-Seq_HELA_Human2.43127163
29PDX1_19855005_ChIP-ChIP_MIN6_Mouse2.39847198
30E2F1_18555785_ChIP-Seq_MESCs_Mouse2.35261247
31DCP1A_22483619_ChIP-Seq_HELA_Human2.32278682
32REST_18959480_ChIP-ChIP_MESCs_Mouse2.22069030
33REST_21632747_ChIP-Seq_MESCs_Mouse2.20971608
34FOXP3_21729870_ChIP-Seq_TREG_Human2.16292985
35GBX2_23144817_ChIP-Seq_PC3_Human2.10558136
36RBPJ_22232070_ChIP-Seq_NCS_Mouse2.10405695
37GABP_19822575_ChIP-Seq_HepG2_Human2.07875406
38* TTF2_22483619_ChIP-Seq_HELA_Human2.06966681
39IGF1R_20145208_ChIP-Seq_DFB_Human2.06763491
40GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.04152997
41* ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.99232687
42FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.96255309
43TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.94015676
44FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.91164622
45MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.89369034
46SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.84288241
47CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.82752489
48NELFA_20434984_ChIP-Seq_ESCs_Mouse1.81480880
49SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.75483804
50HOXB4_20404135_ChIP-ChIP_EML_Mouse1.74982324
51IKZF1_21737484_ChIP-ChIP_HCT116_Human1.74902459
52ERG_20887958_ChIP-Seq_HPC-7_Mouse1.70691987
53E2F4_17652178_ChIP-ChIP_JURKAT_Human1.65868957
54MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.60930252
55CBX2_27304074_Chip-Seq_ESCs_Mouse1.59991587
56JARID2_20064375_ChIP-Seq_MESCs_Mouse1.56860853
57SUZ12_27294783_Chip-Seq_ESCs_Mouse1.56746109
58YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.56425249
59EZH2_27294783_Chip-Seq_ESCs_Mouse1.56369678
60ZFX_18555785_ChIP-Seq_MESCs_Mouse1.55432456
61POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.54870563
62CTBP2_25329375_ChIP-Seq_LNCAP_Human1.52514337
63MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.52036382
64FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.51424633
65PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.50666009
66VDR_22108803_ChIP-Seq_LS180_Human1.49703609
67ELK1_19687146_ChIP-ChIP_HELA_Human1.48949058
68MYCN_18555785_ChIP-Seq_MESCs_Mouse1.47947980
69ZFP57_27257070_Chip-Seq_ESCs_Mouse1.46595721
70TP53_22573176_ChIP-Seq_HFKS_Human1.46172113
71SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.40884960
72EZH2_27304074_Chip-Seq_ESCs_Mouse1.39713826
73CTBP1_25329375_ChIP-Seq_LNCAP_Human1.39019088
74CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.37537467
75E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.37389620
76EED_16625203_ChIP-ChIP_MESCs_Mouse1.37170085
77RNF2_27304074_Chip-Seq_NSC_Mouse1.36712889
78BMI1_23680149_ChIP-Seq_NPCS_Mouse1.35644855
79SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.34523129
80CTCF_18555785_ChIP-Seq_MESCs_Mouse1.32395655
81CIITA_25753668_ChIP-Seq_RAJI_Human1.31979493
82SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.31794699
83JARID2_20075857_ChIP-Seq_MESCs_Mouse1.31366611
84DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.30324650
85SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.28886090
86SIN3A_21632747_ChIP-Seq_MESCs_Mouse1.26159415
87SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.25753478
88PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse1.22444823
89EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.20881486
90NOTCH1_21737748_ChIP-Seq_TLL_Human1.18448384
91MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.17940580
92ETV2_25802403_ChIP-Seq_MESCs_Mouse1.17303920
93MYC_18940864_ChIP-ChIP_HL60_Human1.15144463
94HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.15075337
95MTF2_20144788_ChIP-Seq_MESCs_Mouse1.14597188
96ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.12995998
97GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.12623437
98ERA_21632823_ChIP-Seq_H3396_Human1.10208636
99TAF2_19829295_ChIP-Seq_ESCs_Human1.08076576
100* BCL6_27268052_Chip-Seq_Bcells_Human1.07732056
101SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.07180095
102RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.06716007
103LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.05804459
104TAF15_26573619_Chip-Seq_HEK293_Human1.05064734
105YY1_22570637_ChIP-Seq_MALME-3M_Human1.03969571
106IRF1_19129219_ChIP-ChIP_H3396_Human1.03922008
107CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.03434046
108BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.02988296
109RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.02024803
110CNOT3_19339689_ChIP-ChIP_MESCs_Mouse1.01776977
111* MYC_19829295_ChIP-Seq_ESCs_Human1.01553405
112CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human1.00689613
113HTT_18923047_ChIP-ChIP_STHdh_Human1.00402153
114NCOR_22424771_ChIP-Seq_293T_Human0.99599529
115NANOG_18555785_ChIP-Seq_MESCs_Mouse0.99343180
116DROSHA_22980978_ChIP-Seq_HELA_Human0.98791853
117EBNA2_21746931_ChIP-Seq_IB4-LCL_Human0.98717626
118POU5F1_18358816_ChIP-ChIP_MESCs_Mouse0.98715425
119ELF1_20517297_ChIP-Seq_JURKAT_Human0.98000716
120ELK1_22589737_ChIP-Seq_MCF10A_Human0.95948557
121CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse0.95517740
122FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse0.95134880
123ESRRB_18555785_ChIP-Seq_MESCs_Mouse0.95069678
124GATA3_21878914_ChIP-Seq_MCF-7_Human0.95066524
125SUZ12_18974828_ChIP-Seq_MESCs_Mouse0.94807308
126E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human0.94688922
127NANOG_20526341_ChIP-Seq_ESCs_Human0.94265984
128* PBX1_22567123_ChIP-ChIP_OVCAR3_Human0.93572530
129RARB_27405468_Chip-Seq_BRAIN_Mouse0.92300548
130P300_19829295_ChIP-Seq_ESCs_Human0.91021690
131PHC1_16625203_ChIP-ChIP_MESCs_Mouse0.90214745
132* KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.90168327
133CTCF_27219007_Chip-Seq_Bcells_Human0.89506737
134EZH2_18974828_ChIP-Seq_MESCs_Mouse0.88985659
135RNF2_18974828_ChIP-Seq_MESCs_Mouse0.88985659
136FUS_26573619_Chip-Seq_HEK293_Human0.88880804
137STAT1_20625510_ChIP-Seq_HELA_Human0.88597110
138GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.87936913
139EBNA1_20929547_Chip-Seq_RAJI-cells_Human0.87915571
140* CTCF_20526341_ChIP-Seq_ESCs_Human0.87629757
141KDM5A_27292631_Chip-Seq_BREAST_Human0.87411165
142CEBPB_23403033_ChIP-Seq_LIVER_Mouse0.87193035
143EWS_26573619_Chip-Seq_HEK293_Human0.87132069
144E2F1_21310950_ChIP-Seq_MCF-7_Human0.87109368
145SRY_22984422_ChIP-ChIP_TESTIS_Rat0.86979288
146CEBPA_26348894_ChIP-Seq_LIVER_Mouse0.86886961
147FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.86163975
148RNF2_27304074_Chip-Seq_ESCs_Mouse0.84963547
149GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse0.84831913
150* SPI1_22096565_ChIP-ChIP_GC-B_Mouse0.83992482
151SCL_19346495_ChIP-Seq_HPC-7_Human0.83390225
152PADI4_21655091_ChIP-ChIP_MCF-7_Human0.83383170
153RBPJ_21746931_ChIP-Seq_IB4-LCL_Human0.82850206
154TBX5_21415370_ChIP-Seq_HL-1_Mouse0.81084045
155HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.77717514
156* FOXP1_21924763_ChIP-Seq_HESCs_Human0.75470450
157TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat0.72689561
158CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.72612211
159TRIM28_19339689_ChIP-ChIP_MESCs_Mouse0.71758472
160SOX2_18555785_ChIP-Seq_MESCs_Mouse0.71141147
161TCFCP2L1_18555785_ChIP-Seq_MESCs_Mouse0.70059067
162KLF4_18555785_ChIP-Seq_MESCs_Mouse0.69522832
163PU.1_20513432_ChIP-Seq_Bcells_Mouse0.68915669

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0009379_abnormal_foot_pigmentation3.91707440
2MP0003806_abnormal_nucleotide_metabolis3.11952599
3MP0001529_abnormal_vocalization2.90528547
4MP0002396_abnormal_hematopoietic_system2.56390755
5MP0005410_abnormal_fertilization2.54326444
6MP0006292_abnormal_olfactory_placode2.51057546
7MP0006036_abnormal_mitochondrial_physio2.49840498
8MP0003693_abnormal_embryo_hatching2.39009919
9MP0008058_abnormal_DNA_repair2.32474576
10MP0001984_abnormal_olfaction2.30128667
11MP0010094_abnormal_chromosome_stability2.27289423
12MP0003880_abnormal_central_pattern2.19036332
13MP0003122_maternal_imprinting2.18378507
14MP0005075_abnormal_melanosome_morpholog2.18031734
15MP0001986_abnormal_taste_sensitivity2.09126702
16MP0001905_abnormal_dopamine_level2.05997037
17MP0004957_abnormal_blastocyst_morpholog2.04387555
18MP0003186_abnormal_redox_activity2.04094274
19MP0004147_increased_porphyrin_level2.01343922
20MP0002736_abnormal_nociception_after1.96614089
21MP0002063_abnormal_learning/memory/cond1.95184073
22MP0005645_abnormal_hypothalamus_physiol1.95155368
23MP0003787_abnormal_imprinting1.95097664
24MP0002102_abnormal_ear_morphology1.94178190
25MP0001968_abnormal_touch/_nociception1.89994519
26MP0008057_abnormal_DNA_replication1.87654055
27MP0001486_abnormal_startle_reflex1.80731856
28MP0002653_abnormal_ependyma_morphology1.78831813
29MP0004142_abnormal_muscle_tone1.75965491
30MP0001188_hyperpigmentation1.74386695
31MP0002160_abnormal_reproductive_system1.73393058
32MP0002938_white_spotting1.73390710
33MP0004133_heterotaxia1.70410993
34MP0003123_paternal_imprinting1.69891822
35MP0003077_abnormal_cell_cycle1.69093445
36MP0008007_abnormal_cellular_replicative1.68529015
37MP0002822_catalepsy1.67370771
38MP0002837_dystrophic_cardiac_calcinosis1.66358781
39MP0003011_delayed_dark_adaptation1.64362906
40MP0001764_abnormal_homeostasis1.60490584
41MP0005409_darkened_coat_color1.60349643
42MP0002067_abnormal_sensory_capabilities1.58863051
43MP0002557_abnormal_social/conspecific_i1.56631578
44MP0002132_abnormal_respiratory_system1.55811299
45MP0008877_abnormal_DNA_methylation1.54338928
46MP0008932_abnormal_embryonic_tissue1.51380570
47MP0002735_abnormal_chemical_nociception1.50012905
48MP0005174_abnormal_tail_pigmentation1.47624311
49MP0003121_genomic_imprinting1.47210331
50MP0001501_abnormal_sleep_pattern1.44273498
51MP0000778_abnormal_nervous_system1.44091487
52MP0004742_abnormal_vestibular_system1.41213099
53MP0006035_abnormal_mitochondrial_morpho1.40690481
54MP0002095_abnormal_skin_pigmentation1.37373436
55MP0002734_abnormal_mechanical_nocicepti1.33119673
56MP0002272_abnormal_nervous_system1.33095138
57MP0000372_irregular_coat_pigmentation1.31768092
58MP0004924_abnormal_behavior1.31276918
59MP0005386_behavior/neurological_phenoty1.31276918
60MP0008875_abnormal_xenobiotic_pharmacok1.25501091
61MP0001929_abnormal_gametogenesis1.25200283
62MP0003698_abnormal_male_reproductive1.25048415
63MP0005253_abnormal_eye_physiology1.23930448
64MP0004145_abnormal_muscle_electrophysio1.23746711
65MP0000490_abnormal_crypts_of1.21166303
66MP0002210_abnormal_sex_determination1.18608085
67MP0002882_abnormal_neuron_morphology1.17264204
68MP0002638_abnormal_pupillary_reflex1.16813958
69MP0000955_abnormal_spinal_cord1.16564524
70MP0000015_abnormal_ear_pigmentation1.15240640
71MP0008872_abnormal_physiological_respon1.14648193
72MP0005646_abnormal_pituitary_gland1.14393260
73MP0003111_abnormal_nucleus_morphology1.13852247
74MP0004885_abnormal_endolymph1.13393153
75MP0000749_muscle_degeneration1.12554691
76MP0008789_abnormal_olfactory_epithelium1.12164770
77MP0001502_abnormal_circadian_rhythm1.10941208
78MP0005397_hematopoietic_system_phenotyp1.10859316
79MP0001545_abnormal_hematopoietic_system1.10859316
80MP0002184_abnormal_innervation1.09034540
81MP0004043_abnormal_pH_regulation1.07485863
82MP0003195_calcinosis1.06756515
83MP0004811_abnormal_neuron_physiology1.06722873
84MP0008569_lethality_at_weaning1.06474149
85MP0002234_abnormal_pharynx_morphology1.06060585
86MP0010386_abnormal_urinary_bladder1.05306119
87MP0003786_premature_aging1.04400646
88MP0005394_taste/olfaction_phenotype1.04196853
89MP0005499_abnormal_olfactory_system1.04196853
90MP0009333_abnormal_splenocyte_physiolog1.02979475
91MP0002089_abnormal_postnatal_growth/wei1.02762756
92MP0005551_abnormal_eye_electrophysiolog1.02584725
93MP0002066_abnormal_motor_capabilities/c1.02538488
94MP0009697_abnormal_copulation1.02504647
95MP0000358_abnormal_cell_content/1.01227436
96MP0003633_abnormal_nervous_system0.99968349
97MP0001440_abnormal_grooming_behavior0.99607619
98MP0001970_abnormal_pain_threshold0.98891861
99MP0001145_abnormal_male_reproductive0.97391919
100MP0006054_spinal_hemorrhage0.97306102
101MP0000049_abnormal_middle_ear0.95692889
102MP0004270_analgesia0.95559730
103MP0001963_abnormal_hearing_physiology0.94053556
104MP0003137_abnormal_impulse_conducting0.93916979
105MP0003136_yellow_coat_color0.93902494
106MP0005379_endocrine/exocrine_gland_phen0.93705334
107MP0000678_abnormal_parathyroid_gland0.90983983
108MP0006276_abnormal_autonomic_nervous0.90505529
109MP0008995_early_reproductive_senescence0.90327917
110MP0003329_amyloid_beta_deposits0.90032248
111MP0005389_reproductive_system_phenotype0.89016266
112MP0003656_abnormal_erythrocyte_physiolo0.87898661
113MP0009046_muscle_twitch0.87566370
114MP0001485_abnormal_pinna_reflex0.87379293
115MP0002163_abnormal_gland_morphology0.87314255
116MP0003879_abnormal_hair_cell0.86689263
117MP0004808_abnormal_hematopoietic_stem0.86165899
118MP0009745_abnormal_behavioral_response0.85831157
119MP0002572_abnormal_emotion/affect_behav0.85623769
120MP0005636_abnormal_mineral_homeostasis0.84815259
121MP0000631_abnormal_neuroendocrine_gland0.84306757
122MP0000681_abnormal_thyroid_gland0.83861947
123MP0002751_abnormal_autonomic_nervous0.83112488
124MP0002064_seizures0.82534545
125MP0005423_abnormal_somatic_nervous0.82466410
126MP0002733_abnormal_thermal_nociception0.82441972
127MP0000653_abnormal_sex_gland0.82207783
128MP0000026_abnormal_inner_ear0.82110882
129MP0002229_neurodegeneration0.81901829
130MP0002909_abnormal_adrenal_gland0.81462434
131MP0005084_abnormal_gallbladder_morpholo0.79981146
132MP0003635_abnormal_synaptic_transmissio0.79442916
133MP0002876_abnormal_thyroid_physiology0.79277704
134MP0002069_abnormal_eating/drinking_beha0.78848435
135MP0006072_abnormal_retinal_apoptosis0.78481299
136MP0003631_nervous_system_phenotype0.76468634
137MP0005266_abnormal_metabolism0.76138738
138MP0000639_abnormal_adrenal_gland0.74711634
139MP0002152_abnormal_brain_morphology0.74161384
140MP0000313_abnormal_cell_death0.72653136
141MP0005195_abnormal_posterior_eye0.72168465
142MP0005535_abnormal_body_temperature0.71816149
143MP0004859_abnormal_synaptic_plasticity0.70074008
144MP0003646_muscle_fatigue0.70057816
145MP0002752_abnormal_somatic_nervous0.68017278
146MP0000920_abnormal_myelination0.67724242
147MP0002161_abnormal_fertility/fecundity0.67562802

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of cells of the erythroid lineage (HP:0012130)5.01905478
2Hepatocellular necrosis (HP:0001404)5.01244279
3Mitochondrial inheritance (HP:0001427)4.86402389
4Abnormal number of erythroid precursors (HP:0012131)4.84887511
5Acute necrotizing encephalopathy (HP:0006965)4.57091374
6Abnormal mitochondria in muscle tissue (HP:0008316)4.48704898
7Increased CSF lactate (HP:0002490)4.37973405
8Hepatic necrosis (HP:0002605)4.32329416
9Abnormal activity of mitochondrial respiratory chain (HP:0011922)4.28498988
10Decreased activity of mitochondrial respiratory chain (HP:0008972)4.28498988
11Myokymia (HP:0002411)4.12539617
12Increased hepatocellular lipid droplets (HP:0006565)4.07369067
13Acute encephalopathy (HP:0006846)3.89562867
14Type I transferrin isoform profile (HP:0003642)3.81984523
15Lipid accumulation in hepatocytes (HP:0006561)3.80630801
16Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)3.76347892
17Increased serum lactate (HP:0002151)3.75353266
18Increased intramyocellular lipid droplets (HP:0012240)3.72015055
193-Methylglutaconic aciduria (HP:0003535)3.71390673
20Focal motor seizures (HP:0011153)3.70441564
21Reticulocytopenia (HP:0001896)3.67905796
22Renal Fanconi syndrome (HP:0001994)3.66714197
23Progressive macrocephaly (HP:0004481)3.55457238
24Increased serum pyruvate (HP:0003542)3.48630834
25Abnormality of glycolysis (HP:0004366)3.48630834
26Aplastic anemia (HP:0001915)3.45307530
27Muscle abnormality related to mitochondrial dysfunction (HP:0003800)3.41804414
28Polyphagia (HP:0002591)3.32475525
29Increased muscle lipid content (HP:0009058)3.25831517
30Lactic acidosis (HP:0003128)3.23045221
31Cerebral hypomyelination (HP:0006808)3.19730581
32Exercise intolerance (HP:0003546)3.13711822
33Abnormal respiratory epithelium morphology (HP:0012253)3.06140926
34Abnormal respiratory motile cilium morphology (HP:0005938)3.06140926
35Abnormality of midbrain morphology (HP:0002418)3.04067287
36Molar tooth sign on MRI (HP:0002419)3.04067287
37Severe visual impairment (HP:0001141)3.01127897
38Macrocytic anemia (HP:0001972)2.97379480
39Exertional dyspnea (HP:0002875)2.94235364
40Abnormal isoelectric focusing of serum transferrin (HP:0003160)2.92282234
41Abnormal protein N-linked glycosylation (HP:0012347)2.92282234
42Abnormal protein glycosylation (HP:0012346)2.92282234
43Abnormal glycosylation (HP:0012345)2.92282234
44Respiratory failure (HP:0002878)2.89845469
45Hyperglycinemia (HP:0002154)2.81139291
46Nephronophthisis (HP:0000090)2.79290709
47Respiratory difficulties (HP:0002880)2.69845450
48Aplasia/Hypoplasia of the sacrum (HP:0008517)2.66280489
49Pallor (HP:0000980)2.66103198
50Thrombocytosis (HP:0001894)2.65915494
51Oral leukoplakia (HP:0002745)2.63425388
52True hermaphroditism (HP:0010459)2.62692816
53Focal seizures (HP:0007359)2.62421671
54Abnormal respiratory motile cilium physiology (HP:0012261)2.51058278
55Abnormality of renal resorption (HP:0011038)2.50649339
56Type II lissencephaly (HP:0007260)2.50533615
57Optic disc pallor (HP:0000543)2.50495530
58Pancreatic fibrosis (HP:0100732)2.50264934
59Leukodystrophy (HP:0002415)2.49811929
60Microvesicular hepatic steatosis (HP:0001414)2.49267938
61Abnormal ciliary motility (HP:0012262)2.48686234
62Pancytopenia (HP:0001876)2.47373048
63Abnormal eating behavior (HP:0100738)2.45861320
64Decreased electroretinogram (ERG) amplitude (HP:0000654)2.45525492
65Nephrogenic diabetes insipidus (HP:0009806)2.42326283
66Epileptic encephalopathy (HP:0200134)2.41399174
67Medial flaring of the eyebrow (HP:0010747)2.41212183
68Reduced antithrombin III activity (HP:0001976)2.40750243
69Abnormality of the heme biosynthetic pathway (HP:0010472)2.40546350
70Respiratory insufficiency due to defective ciliary clearance (HP:0200073)2.40287670
71Birth length less than 3rd percentile (HP:0003561)2.39991435
72Gait imbalance (HP:0002141)2.39336237
73Emotional lability (HP:0000712)2.38188523
74Dynein arm defect of respiratory motile cilia (HP:0012255)2.37797511
75Absent/shortened dynein arms (HP:0200106)2.37797511
76Limb dystonia (HP:0002451)2.36355985
77Failure to thrive in infancy (HP:0001531)2.33296116
78Absent rod-and cone-mediated responses on ERG (HP:0007688)2.32104545
79Hemiparesis (HP:0001269)2.32028581
80Congenital primary aphakia (HP:0007707)2.31566989
81Febrile seizures (HP:0002373)2.29862765
82CNS demyelination (HP:0007305)2.28238456
83Rhinitis (HP:0012384)2.26591696
84Cerebral edema (HP:0002181)2.24581896
85Progressive microcephaly (HP:0000253)2.22582611
86Abnormality of the renal medulla (HP:0100957)2.22430933
87Congenital stationary night blindness (HP:0007642)2.20070455
88Progressive cerebellar ataxia (HP:0002073)2.15813329
89Postnatal microcephaly (HP:0005484)2.14810578
90Agitation (HP:0000713)2.14438889
91Lethargy (HP:0001254)2.13436011
92Abnormality of alanine metabolism (HP:0010916)2.11537466
93Hyperalaninemia (HP:0003348)2.11537466
94Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.11537466
95Abnormality of the pons (HP:0007361)2.10636268
96Lissencephaly (HP:0001339)2.08888598
97Microretrognathia (HP:0000308)2.07985634
98Generalized tonic-clonic seizures (HP:0002069)2.07636670
99CNS hypomyelination (HP:0003429)2.05318452
100Ragged-red muscle fibers (HP:0003200)2.05239190
101Cystic liver disease (HP:0006706)2.04477813
102Opisthotonus (HP:0002179)2.03806475
103Methylmalonic aciduria (HP:0012120)2.02942175
104Pancreatic cysts (HP:0001737)2.00249161
105Ketoacidosis (HP:0001993)1.99265953
106Visual hallucinations (HP:0002367)1.97826469
107Amblyopia (HP:0000646)1.96917636
108Neuroendocrine neoplasm (HP:0100634)1.95630180
109Retinal dysplasia (HP:0007973)1.95005233
110Severe muscular hypotonia (HP:0006829)1.94895575
111Methylmalonic acidemia (HP:0002912)1.93691914
112Abolished electroretinogram (ERG) (HP:0000550)1.92913952
113Ketosis (HP:0001946)1.92463665
114Degeneration of anterior horn cells (HP:0002398)1.91851482
115Abnormality of the anterior horn cell (HP:0006802)1.91851482
116Inability to walk (HP:0002540)1.88259402
117Abnormal rod and cone electroretinograms (HP:0008323)1.87680391
118Delayed CNS myelination (HP:0002188)1.87591759
119Petechiae (HP:0000967)1.85581302
120Dialeptic seizures (HP:0011146)1.84616047
121Hypsarrhythmia (HP:0002521)1.83126322
122Rough bone trabeculation (HP:0100670)1.82826240
123Epileptiform EEG discharges (HP:0011182)1.82319417
124Absent speech (HP:0001344)1.81638748
125EEG with generalized epileptiform discharges (HP:0011198)1.80149896
126Hypothermia (HP:0002045)1.79660583
127Supernumerary spleens (HP:0009799)1.78938426
128Absence seizures (HP:0002121)1.78587435
129Hypoplasia of the pons (HP:0012110)1.78209129
130Congenital hepatic fibrosis (HP:0002612)1.78112647
131Specific learning disability (HP:0001328)1.77749450
132Muscular hypotonia of the trunk (HP:0008936)1.77027690
133Hyperphosphaturia (HP:0003109)1.76998660
134Premature graying of hair (HP:0002216)1.76734277
135Decreased central vision (HP:0007663)1.76625877
136Mutism (HP:0002300)1.75902745
137Attenuation of retinal blood vessels (HP:0007843)1.74914762
138Anencephaly (HP:0002323)1.74814528
139Dicarboxylic aciduria (HP:0003215)1.73851763
140Abnormality of dicarboxylic acid metabolism (HP:0010995)1.73851763
141Pachygyria (HP:0001302)1.73710318
142Spastic tetraplegia (HP:0002510)1.73704873
143Unsteady gait (HP:0002317)1.72387408
144Delusions (HP:0000746)1.71338276
145Sclerocornea (HP:0000647)1.69980831
146IgM deficiency (HP:0002850)1.69595885
147Vaginal atresia (HP:0000148)1.69121526
14811 pairs of ribs (HP:0000878)1.67873223
149Poor suck (HP:0002033)1.66347670
150Genital tract atresia (HP:0001827)1.64197268
151Pheochromocytoma (HP:0002666)1.62726182
152Postaxial foot polydactyly (HP:0001830)1.61578214

Predicted kinase interactions (KEA)

RankGene SetZ-score
1STK163.50266448
2MAP4K23.33922004
3VRK13.33798199
4TNIK3.14616305
5BUB13.06013355
6CDK192.90925961
7MARK12.79287689
8WEE12.68708670
9NME22.65580911
10EIF2AK12.61503493
11PINK12.46521147
12PIM22.44175544
13EIF2AK32.30291210
14VRK22.25334876
15MAP3K122.20559885
16TSSK62.19886179
17TAOK32.18018906
18EPHA42.13725249
19CCNB12.07352853
20NME11.99459595
21CASK1.77861575
22CSNK1G21.71139497
23TESK21.68589342
24PAK61.63479193
25MUSK1.62389163
26TRIM281.61660347
27MAP2K71.59118397
28PHKG21.58481830
29PHKG11.58481830
30FLT31.57406150
31TGFBR11.57210674
32DAPK11.54390059
33SCYL21.54107645
34CSNK1A1L1.52286398
35OXSR11.49025166
36CSNK1G11.44910896
37BCKDK1.38860134
38ADRBK21.34707550
39CDK81.33582781
40CDC71.30845769
41MKNK11.30245887
42ACVR1B1.29786728
43MYLK1.28442536
44NTRK21.21595564
45NUAK11.19690672
46PAK31.17487103
47BMPR1B1.17082111
48MAPKAPK51.14970652
49ARAF1.10323290
50DYRK31.08105805
51PRKCG1.08062891
52FRK1.04883961
53SRPK11.04864066
54STK391.02825639
55MAP2K41.02483080
56TESK11.02260363
57ILK1.00787774
58PASK0.99321308
59BRSK20.97713138
60PDK30.97028252
61PDK40.97028252
62ZAK0.96202388
63CDK70.95527997
64DYRK20.92957388
65TEC0.92572922
66TLK10.92313142
67PBK0.90239651
68MAP3K110.89931321
69SIK20.87762852
70YES10.86234574
71RPS6KB20.85878612
72BTK0.84940150
73MAP2K60.84854662
74MST40.81655398
75GRK70.81119237
76CAMKK20.81066447
77EPHA30.80474431
78TNK20.80458236
79PRPF4B0.80261868
80INSRR0.79774605
81BRAF0.76202603
82CSNK1G30.75975671
83CAMKK10.75698946
84WNK40.74745725
85CAMK2A0.74527883
86LIMK10.73769614
87PRKD30.73637969
88CDK50.73631332
89ERBB30.73127382
90RPS6KA50.71751049
91AURKA0.71722929
92PKN10.70643881
93DYRK1A0.70598966
94PLK30.69318468
95MAPK130.67509113
96BCR0.66937889
97MKNK20.65996365
98BRSK10.65732347
99PLK20.65689151
100KIT0.64267282
101CSNK2A20.64148077
102MAPK150.63281356
103PRKCE0.62850699
104PLK40.62507678
105PAK10.61786556
106GRK50.60879893
107OBSCN0.59407298
108MAP3K40.59270270
109PRKACA0.58917309
110CSNK1A10.58784112
111MINK10.58356977
112CSNK2A10.57799779
113PAK40.56911747
114CDK140.55059468
115KDR0.54943408
116CAMK10.53949237
117CAMK2G0.53843730
118ABL20.53670097
119MAP3K60.53172922
120ATR0.52150458
121WNK30.51184054
122DAPK30.50481277
123PLK10.50359279
124GRK60.47778666
125DYRK1B0.47567716
126CAMK2B0.47557680
127PRKCQ0.47386488
128ADRBK10.46415423
129RPS6KA40.45387790
130PRKCI0.45138980
131CDK150.44764092
132RAF10.43959636
133PKN20.42981355
134NTRK30.41943371
135PRKCA0.41522786
136CAMK2D0.41197569
137EIF2AK20.40125245
138MAPKAPK30.39360009
139GRK10.38246674
140UHMK10.38106941
141TIE10.37663272
142CDK11A0.35878745
143TXK0.35780687
144PTK2B0.35005384
145PRKG10.34905597
146CLK10.34452606
147CHEK20.33700862
148CSF1R0.33412529
149CDK180.33399404
150DAPK20.32642067
151STK110.30473873

Predicted pathways (KEGG)

RankGene SetZ-score
1Ribosome_Homo sapiens_hsa030105.06362654
2DNA replication_Homo sapiens_hsa030303.88519206
3Proteasome_Homo sapiens_hsa030503.80193900
4Oxidative phosphorylation_Homo sapiens_hsa001903.51939087
5RNA polymerase_Homo sapiens_hsa030203.35511653
6Parkinsons disease_Homo sapiens_hsa050123.25087376
7Mismatch repair_Homo sapiens_hsa034303.19757092
8Protein export_Homo sapiens_hsa030602.93693269
9Huntingtons disease_Homo sapiens_hsa050162.53925109
10Pyrimidine metabolism_Homo sapiens_hsa002402.52481443
11Homologous recombination_Homo sapiens_hsa034402.24923991
12Spliceosome_Homo sapiens_hsa030402.23972727
13Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.22952818
14Alzheimers disease_Homo sapiens_hsa050102.19478672
15Nucleotide excision repair_Homo sapiens_hsa034202.16670619
16Base excision repair_Homo sapiens_hsa034102.09225296
17GABAergic synapse_Homo sapiens_hsa047271.71066005
18Purine metabolism_Homo sapiens_hsa002301.69845689
19Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.67771250
20Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.65628514
21Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.65019495
22Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.64518831
23Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.58590396
24Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.56082989
25Morphine addiction_Homo sapiens_hsa050321.50391380
26RNA transport_Homo sapiens_hsa030131.48891100
27Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.48869497
28Basal transcription factors_Homo sapiens_hsa030221.43095379
29Fatty acid elongation_Homo sapiens_hsa000621.42156825
30RNA degradation_Homo sapiens_hsa030181.38780302
31N-Glycan biosynthesis_Homo sapiens_hsa005101.36363453
32Phototransduction_Homo sapiens_hsa047441.32002861
33Insulin secretion_Homo sapiens_hsa049111.29308127
34Non-homologous end-joining_Homo sapiens_hsa034501.26933367
35Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.25337885
36Folate biosynthesis_Homo sapiens_hsa007901.23403454
37Cardiac muscle contraction_Homo sapiens_hsa042601.21807702
38Pyruvate metabolism_Homo sapiens_hsa006201.20476205
39Maturity onset diabetes of the young_Homo sapiens_hsa049501.16357500
40One carbon pool by folate_Homo sapiens_hsa006701.16346591
41Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.15338476
42Primary bile acid biosynthesis_Homo sapiens_hsa001201.14893496
43Cysteine and methionine metabolism_Homo sapiens_hsa002701.13536353
44Glutamatergic synapse_Homo sapiens_hsa047241.12328172
45Sulfur relay system_Homo sapiens_hsa041221.08522468
46Nitrogen metabolism_Homo sapiens_hsa009101.07094578
47Salivary secretion_Homo sapiens_hsa049701.04991588
48Cocaine addiction_Homo sapiens_hsa050301.04030443
49Glutathione metabolism_Homo sapiens_hsa004801.02980393
50Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.02095227
51Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.01100667
52Fanconi anemia pathway_Homo sapiens_hsa034600.99095901
53Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.98049303
54Dopaminergic synapse_Homo sapiens_hsa047280.97121372
55Cyanoamino acid metabolism_Homo sapiens_hsa004600.96522411
56Amphetamine addiction_Homo sapiens_hsa050310.95378744
57Cell cycle_Homo sapiens_hsa041100.88514504
58Biosynthesis of amino acids_Homo sapiens_hsa012300.88472472
59Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.86911785
60Metabolic pathways_Homo sapiens_hsa011000.86250673
61Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.86190151
62Pentose phosphate pathway_Homo sapiens_hsa000300.84529072
63Tryptophan metabolism_Homo sapiens_hsa003800.82566138
64Carbon metabolism_Homo sapiens_hsa012000.81819679
652-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.77797813
66beta-Alanine metabolism_Homo sapiens_hsa004100.75658538
67SNARE interactions in vesicular transport_Homo sapiens_hsa041300.72368265
68Vibrio cholerae infection_Homo sapiens_hsa051100.70800925
69Olfactory transduction_Homo sapiens_hsa047400.69858037
70Fructose and mannose metabolism_Homo sapiens_hsa000510.66192253
71Arachidonic acid metabolism_Homo sapiens_hsa005900.65328240
72Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.63212137
73Glycosaminoglycan degradation_Homo sapiens_hsa005310.62957800
74Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.60526433
75Galactose metabolism_Homo sapiens_hsa000520.57397106
76Collecting duct acid secretion_Homo sapiens_hsa049660.56931320
77Calcium signaling pathway_Homo sapiens_hsa040200.55323037
78Aldosterone synthesis and secretion_Homo sapiens_hsa049250.48041397
79Drug metabolism - other enzymes_Homo sapiens_hsa009830.47972609
80Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.46936045
81Fatty acid degradation_Homo sapiens_hsa000710.46646933
82Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.46210144
83Propanoate metabolism_Homo sapiens_hsa006400.45377070
84Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.44035770
85Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.43355177
86Steroid hormone biosynthesis_Homo sapiens_hsa001400.42389700
87Gastric acid secretion_Homo sapiens_hsa049710.42147246
88Cholinergic synapse_Homo sapiens_hsa047250.41700765
89Phenylalanine metabolism_Homo sapiens_hsa003600.41307488
90Arginine and proline metabolism_Homo sapiens_hsa003300.41280870
91Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.41169255
92Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.41065389
93Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.39919096
94Chemical carcinogenesis_Homo sapiens_hsa052040.39898973
95Oxytocin signaling pathway_Homo sapiens_hsa049210.39430176
96Peroxisome_Homo sapiens_hsa041460.39388516
97Steroid biosynthesis_Homo sapiens_hsa001000.38632221
98Epstein-Barr virus infection_Homo sapiens_hsa051690.37091457
99Long-term depression_Homo sapiens_hsa047300.36657845
100Tyrosine metabolism_Homo sapiens_hsa003500.36275936
101Circadian rhythm_Homo sapiens_hsa047100.35025859
102Alcoholism_Homo sapiens_hsa050340.34004003
103mRNA surveillance pathway_Homo sapiens_hsa030150.33488677
104Synaptic vesicle cycle_Homo sapiens_hsa047210.32220793
105Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.31845293
106Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.31113577
107Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.30301889
108Oocyte meiosis_Homo sapiens_hsa041140.27735963
109cAMP signaling pathway_Homo sapiens_hsa040240.25079013
110Other glycan degradation_Homo sapiens_hsa005110.23306702
111Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.23128730
112Sulfur metabolism_Homo sapiens_hsa009200.22443008
113Ether lipid metabolism_Homo sapiens_hsa005650.21997988
114Butanoate metabolism_Homo sapiens_hsa006500.21235175
115Renin-angiotensin system_Homo sapiens_hsa046140.20012059
116Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.19159584
117alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.15566872
118Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.15501828
119Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.14863384
120Linoleic acid metabolism_Homo sapiens_hsa005910.14009884
121Systemic lupus erythematosus_Homo sapiens_hsa053220.11297772
122Sphingolipid metabolism_Homo sapiens_hsa006000.10589132
123Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.10524287
124Thyroid cancer_Homo sapiens_hsa052160.10345755
125Pentose and glucuronate interconversions_Homo sapiens_hsa000400.09749736
126Nicotine addiction_Homo sapiens_hsa050330.09507286
127Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.07518622
128Serotonergic synapse_Homo sapiens_hsa047260.06962120
129Regulation of autophagy_Homo sapiens_hsa041400.06567351
130Taste transduction_Homo sapiens_hsa047420.06229450
131Fatty acid metabolism_Homo sapiens_hsa012120.06187078
132Circadian entrainment_Homo sapiens_hsa047130.06000013
133Vitamin B6 metabolism_Homo sapiens_hsa007500.05769039

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