ABHD17B

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1fatty acid elongation (GO:0030497)8.04145593
2ensheathment of neurons (GO:0007272)7.63696356
3axon ensheathment (GO:0008366)7.63696356
4myelination (GO:0042552)7.61490920
5long-chain fatty acid biosynthetic process (GO:0042759)6.09792982
6negative regulation of neurotransmitter secretion (GO:0046929)5.96945222
7negative regulation of neurotransmitter transport (GO:0051589)5.17430561
8cholesterol biosynthetic process (GO:0006695)5.04161227
9oligodendrocyte differentiation (GO:0048709)5.00859097
10myelin maintenance (GO:0043217)4.88135331
11glycerophospholipid catabolic process (GO:0046475)4.85982823
12presynaptic membrane assembly (GO:0097105)4.60373963
13photoreceptor cell differentiation (GO:0046530)4.56166639
14eye photoreceptor cell differentiation (GO:0001754)4.56166639
15asymmetric protein localization (GO:0008105)4.49792972
16presynaptic membrane organization (GO:0097090)4.49580737
17sterol biosynthetic process (GO:0016126)4.41969760
18astrocyte development (GO:0014002)4.40961371
19apical protein localization (GO:0045176)4.35597439
20positive regulation of oligodendrocyte differentiation (GO:0048714)4.35014009
21L-amino acid import (GO:0043092)4.34336297
22establishment of mitochondrion localization (GO:0051654)4.30162762
23regulation of collateral sprouting (GO:0048670)4.28966980
24negative regulation of peptidyl-threonine phosphorylation (GO:0010801)4.19694026
25regulation of posttranscriptional gene silencing (GO:0060147)4.19608581
26regulation of gene silencing by miRNA (GO:0060964)4.19608581
27regulation of gene silencing by RNA (GO:0060966)4.19608581
28isoprenoid biosynthetic process (GO:0008299)4.19282736
29creatine metabolic process (GO:0006600)4.17444126
30substantia nigra development (GO:0021762)4.09014599
31response to methylmercury (GO:0051597)4.03864390
32pre-miRNA processing (GO:0031054)4.00162790
33virion attachment to host cell (GO:0019062)3.94575728
34adhesion of symbiont to host cell (GO:0044650)3.94575728
35negative regulation of protein localization to cell surface (GO:2000009)3.90267831
36myelination in peripheral nervous system (GO:0022011)3.89866537
37peripheral nervous system axon ensheathment (GO:0032292)3.89866537
38long-chain fatty-acyl-CoA biosynthetic process (GO:0035338)3.89734870
39neuron cell-cell adhesion (GO:0007158)3.80753344
40response to redox state (GO:0051775)3.74646647
41import into cell (GO:0098657)3.73274020
42magnesium ion transport (GO:0015693)3.69771161
43amyloid precursor protein metabolic process (GO:0042982)3.69399681
44activated T cell proliferation (GO:0050798)3.57637063
45long-chain fatty-acyl-CoA metabolic process (GO:0035336)3.56945258
46protein palmitoylation (GO:0018345)3.49675468
47cerebral cortex radially oriented cell migration (GO:0021799)3.47789285
48chromatin remodeling at centromere (GO:0031055)3.46285557
49amino acid import (GO:0043090)3.44937250
50positive regulation of action potential (GO:0045760)3.43032942
51glycosylceramide metabolic process (GO:0006677)3.42730541
52forebrain neuron differentiation (GO:0021879)3.40355987
53regulation of histone H3-K9 methylation (GO:0051570)3.40053552
54response to lipoprotein particle (GO:0055094)3.39286670
55peptidyl-tyrosine autophosphorylation (GO:0038083)3.36005881
56fatty-acyl-CoA biosynthetic process (GO:0046949)3.32638242
57cellular response to epinephrine stimulus (GO:0071872)3.31112848
58pyrimidine nucleobase catabolic process (GO:0006208)3.31100404
59axon development (GO:0061564)3.28636453
60leukocyte migration involved in inflammatory response (GO:0002523)3.28206698
61negative regulation of JUN kinase activity (GO:0043508)3.23911382
62pyrimidine dimer repair (GO:0006290)3.23652640
63GPI anchor biosynthetic process (GO:0006506)3.22032561
64negative regulation of translation involved in gene silencing by miRNA (GO:0035278)3.20819781
65negative regulation of translation, ncRNA-mediated (GO:0040033)3.20819781
66regulation of translation, ncRNA-mediated (GO:0045974)3.20819781
67transmission of nerve impulse (GO:0019226)3.19962786
68regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)3.18295430
69regulation of mitotic spindle checkpoint (GO:1903504)3.18295430
70DNA double-strand break processing (GO:0000729)3.17242757
71regulation of development, heterochronic (GO:0040034)3.17220515
72membrane tubulation (GO:0097320)3.17042992
73CENP-A containing nucleosome assembly (GO:0034080)3.16522394
74protein localization to kinetochore (GO:0034501)3.13376145
75negative regulation of axonogenesis (GO:0050771)3.12111967
76GPI anchor metabolic process (GO:0006505)3.12057561
77limb bud formation (GO:0060174)3.11541198
78nucleotide transmembrane transport (GO:1901679)3.11517344
79fatty-acyl-CoA metabolic process (GO:0035337)3.11031508
80histone H2B ubiquitination (GO:0033523)3.08809168
81regulation of helicase activity (GO:0051095)3.07491617
82very long-chain fatty acid metabolic process (GO:0000038)3.05111445
83regulation of DNA methylation (GO:0044030)3.00185635
84negative regulation of inclusion body assembly (GO:0090084)2.99642946
85response to epinephrine (GO:0071871)2.98829138
86adult walking behavior (GO:0007628)2.97651669
87preassembly of GPI anchor in ER membrane (GO:0016254)2.97587528
88negative regulation of execution phase of apoptosis (GO:1900118)2.97054171
89nuclear pore organization (GO:0006999)2.95046590
90peripheral nervous system development (GO:0007422)2.94986258
91positive regulation of cellular amine metabolic process (GO:0033240)2.93979706
92peptidyl-cysteine modification (GO:0018198)2.93072665
93protein localization to chromosome, centromeric region (GO:0071459)2.89847816
94positive regulation of glial cell differentiation (GO:0045687)2.89677898
95histone exchange (GO:0043486)2.89510870
96cell fate commitment involved in formation of primary germ layer (GO:0060795)2.87405385
97ncRNA catabolic process (GO:0034661)2.86482880
98membrane assembly (GO:0071709)2.85244960
99adhesion of symbiont to host (GO:0044406)2.85173479
100glial cell development (GO:0021782)2.84490014
101amyloid precursor protein catabolic process (GO:0042987)2.83859053
102nerve growth factor signaling pathway (GO:0038180)2.82696028
103behavioral response to nicotine (GO:0035095)2.82687081
104negative regulation of axon extension (GO:0030517)2.82553167
105regulation of timing of cell differentiation (GO:0048505)2.80573055
106regulation of centriole replication (GO:0046599)2.79136691
107generation of neurons (GO:0048699)2.79037986
108regulation of gene silencing (GO:0060968)2.79032933
109Leydig cell differentiation (GO:0033327)2.78716477
110neural nucleus development (GO:0048857)2.78603351
111negative regulation of transcription regulatory region DNA binding (GO:2000678)2.78130781
112olfactory bulb development (GO:0021772)2.77685136
113nuclear pore complex assembly (GO:0051292)2.76662400
114monoubiquitinated protein deubiquitination (GO:0035520)2.74500017
115regulation of lipoprotein metabolic process (GO:0050746)2.73313771
116regulation of cell fate specification (GO:0042659)2.71274678
117negative regulation of DNA recombination (GO:0045910)2.70447506
118somatic hypermutation of immunoglobulin genes (GO:0016446)2.70222862
119somatic diversification of immune receptors via somatic mutation (GO:0002566)2.70222862
120positive regulation of gliogenesis (GO:0014015)2.69513757
121neuron fate determination (GO:0048664)2.69486387
122spinal cord association neuron differentiation (GO:0021527)2.69185343
123DNA replication-independent nucleosome organization (GO:0034724)2.68879688
124DNA replication-independent nucleosome assembly (GO:0006336)2.68879688
125Rap protein signal transduction (GO:0032486)2.67729721
126peptidyl-threonine dephosphorylation (GO:0035970)2.67471009
127single strand break repair (GO:0000012)2.66857176
128mitotic G2/M transition checkpoint (GO:0044818)2.66411917
129organ growth (GO:0035265)2.65336417
130regulation of chromatin silencing (GO:0031935)2.64542610
131positive regulation of interleukin-17 production (GO:0032740)2.63927412
132non-recombinational repair (GO:0000726)2.63750105
133double-strand break repair via nonhomologous end joining (GO:0006303)2.63750105
134glial cell differentiation (GO:0010001)2.63451024
135acyl-CoA biosynthetic process (GO:0071616)2.63066997
136thioester biosynthetic process (GO:0035384)2.63066997
137interleukin-6-mediated signaling pathway (GO:0070102)2.61353192
138somite development (GO:0061053)2.61016634
139nodal signaling pathway (GO:0038092)2.60639015
140microtubule polymerization or depolymerization (GO:0031109)2.60565998
141neuronal action potential propagation (GO:0019227)2.59999055
142atrial cardiac muscle cell action potential (GO:0086014)2.58797524
143primitive streak formation (GO:0090009)2.58120664
144paraxial mesoderm development (GO:0048339)2.57901485
145neuronal stem cell maintenance (GO:0097150)2.57607125
146exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 2.56496520
147regulation of stem cell maintenance (GO:2000036)2.56417689
148nucleobase catabolic process (GO:0046113)2.55965557
149ceramide biosynthetic process (GO:0046513)2.55051652
150cranial nerve development (GO:0021545)2.54643806
151postsynaptic membrane organization (GO:0001941)2.53762955
152positive regulation of RNA splicing (GO:0033120)2.53706545
153ATP-dependent chromatin remodeling (GO:0043044)2.53264368
154mRNA splice site selection (GO:0006376)2.52528856
155L-serine transport (GO:0015825)2.52500445
156nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)2.52141060
157enteric nervous system development (GO:0048484)2.51674302
158DNA replication-dependent nucleosome organization (GO:0034723)2.51245756
159DNA replication-dependent nucleosome assembly (GO:0006335)2.51245756
160regulation of oligodendrocyte differentiation (GO:0048713)2.51188361
161kinetochore organization (GO:0051383)2.51163266
162neuron remodeling (GO:0016322)2.50404394
163positive regulation of mRNA processing (GO:0050685)2.50375321
164negative regulation of myoblast differentiation (GO:0045662)2.50112384
165negative regulation of mitotic metaphase/anaphase transition (GO:0045841)2.49219764
166negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)2.49219764
167negative regulation of mitotic sister chromatid segregation (GO:0033048)2.49219764
168negative regulation of mitotic sister chromatid separation (GO:2000816)2.49219764
169negative regulation of sister chromatid segregation (GO:0033046)2.49219764
170negative regulation of oligodendrocyte differentiation (GO:0048715)2.47506597
171nonmotile primary cilium assembly (GO:0035058)2.47006954
172regulation of growth hormone secretion (GO:0060123)2.44555961
173regulation of mitotic sister chromatid separation (GO:0010965)2.44537278
174regulation of mitotic sister chromatid segregation (GO:0033047)2.44537278
175regulation of sister chromatid segregation (GO:0033045)2.44537278
176heterochromatin organization (GO:0070828)2.44452645
177lung-associated mesenchyme development (GO:0060484)2.42670174
178regulation of non-canonical Wnt signaling pathway (GO:2000050)2.42420945
179positive regulation of histone H3-K4 methylation (GO:0051571)2.42029526
180epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)2.41147442
181establishment of integrated proviral latency (GO:0075713)2.40832765
182response to UV-C (GO:0010225)2.39983378
183negative regulation of chromosome segregation (GO:0051985)2.39773835
184mechanosensory behavior (GO:0007638)2.38895049
185regulation of cell fate commitment (GO:0010453)2.36474214
186negative regulation of DNA-dependent DNA replication (GO:2000104)2.36413943
187somite rostral/caudal axis specification (GO:0032525)2.33325655
188substrate-independent telencephalic tangential interneuron migration (GO:0021843)2.31403713
189substrate-independent telencephalic tangential migration (GO:0021826)2.31403713
190positive regulation of histone methylation (GO:0031062)2.29604292
191central nervous system myelination (GO:0022010)11.4618654
192axon ensheathment in central nervous system (GO:0032291)11.4618654

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1SOX9_22984422_ChIP-ChIP_TESTIS_Rat3.79344066
2E2F7_22180533_ChIP-Seq_HELA_Human3.77097342
3GBX2_23144817_ChIP-Seq_PC3_Human3.43772361
4E2F4_17652178_ChIP-ChIP_JURKAT_Human2.97273544
5SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse2.96699104
6TAF15_26573619_Chip-Seq_HEK293_Human2.90660630
7E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.80779139
8SALL1_21062744_ChIP-ChIP_HESCs_Human2.80753539
9POU5F1_16153702_ChIP-ChIP_HESCs_Human2.69195609
10MYCN_21190229_ChIP-Seq_SHEP-21N_Human2.66901712
11ZNF274_21170338_ChIP-Seq_K562_Hela2.45639518
12RBPJ_22232070_ChIP-Seq_NCS_Mouse2.41111154
13IGF1R_20145208_ChIP-Seq_DFB_Human2.37034781
14SOX2_16153702_ChIP-ChIP_HESCs_Human2.33240258
15OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse2.28576216
16FOXM1_23109430_ChIP-Seq_U2OS_Human2.24451846
17CEBPD_23245923_ChIP-Seq_MEFs_Mouse2.23082443
18VDR_22108803_ChIP-Seq_LS180_Human2.21632305
19CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons2.14480911
20ER_23166858_ChIP-Seq_MCF-7_Human2.11191653
21JARID2_20064375_ChIP-Seq_MESCs_Mouse2.07517133
22ZFP57_27257070_Chip-Seq_ESCs_Mouse2.06883549
23POU3F2_20337985_ChIP-ChIP_501MEL_Human2.06642201
24VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human2.04612562
25SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.03564335
26KDM5B_21448134_ChIP-Seq_MESCs_Mouse2.00323817
27WT1_19549856_ChIP-ChIP_CCG9911_Human1.97295736
28SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.95852421
29TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.93941923
30MYC_18555785_ChIP-Seq_MESCs_Mouse1.90318333
31CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.84975090
32HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.81348748
33CDX2_19796622_ChIP-Seq_MESCs_Mouse1.80395674
34NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.79994438
35TP63_19390658_ChIP-ChIP_HaCaT_Human1.79881557
36FUS_26573619_Chip-Seq_HEK293_Human1.77365439
37SOX2_19030024_ChIP-ChIP_MESCs_Mouse1.76936719
38EZH2_27304074_Chip-Seq_ESCs_Mouse1.76693404
39MTF2_20144788_ChIP-Seq_MESCs_Mouse1.76192172
40ELK1_19687146_ChIP-ChIP_HELA_Human1.74779338
41NANOG_16153702_ChIP-ChIP_HESCs_Human1.73038891
42EZH2_22144423_ChIP-Seq_EOC_Human1.71975678
43SOX2_18555785_ChIP-Seq_MESCs_Mouse1.70580916
44MYC_18940864_ChIP-ChIP_HL60_Human1.70008111
45EST1_17652178_ChIP-ChIP_JURKAT_Human1.69529114
46SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.68890620
47RNF2_18974828_ChIP-Seq_MESCs_Mouse1.67830345
48EZH2_18974828_ChIP-Seq_MESCs_Mouse1.67830345
49FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.66561106
50CTBP1_25329375_ChIP-Seq_LNCAP_Human1.66060046
51SMAD3_21741376_ChIP-Seq_EPCs_Human1.65927740
52CBX2_27304074_Chip-Seq_ESCs_Mouse1.65785859
53KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.65685989
54KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.63980187
55KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.63980187
56KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.63980187
57GATA1_26923725_Chip-Seq_HPCs_Mouse1.63464050
58AR_21572438_ChIP-Seq_LNCaP_Human1.61954256
59GABP_17652178_ChIP-ChIP_JURKAT_Human1.59347171
60SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.57800382
61FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.57104799
62PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.56506717
63STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse1.55640845
64EZH2_27294783_Chip-Seq_ESCs_Mouse1.55403734
65SUZ12_27294783_Chip-Seq_ESCs_Mouse1.54787245
66NOTCH1_21737748_ChIP-Seq_TLL_Human1.52268234
67SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.50440839
68PIAS1_25552417_ChIP-Seq_VCAP_Human1.50428620
69TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.50055621
70EED_16625203_ChIP-ChIP_MESCs_Mouse1.49263974
71CTBP2_25329375_ChIP-Seq_LNCAP_Human1.47051574
72TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.46753632
73POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.46753632
74RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.46560303
75SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.45647180
76P300_19829295_ChIP-Seq_ESCs_Human1.43300808
77HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.41943665
78RNF2_27304074_Chip-Seq_ESCs_Mouse1.41440309
79SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.35807472
80MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.35149888
81CREB1_15753290_ChIP-ChIP_HEK293T_Human1.34950249
82POU5F1_18347094_ChIP-ChIP_MESCs_Mouse1.34139927
83AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.32059547
84SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.31765328
85PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.30479974
86SOX2_18358816_ChIP-ChIP_MESCs_Mouse1.30379387
87JARID2_20075857_ChIP-Seq_MESCs_Mouse1.30263221
88REST_21632747_ChIP-Seq_MESCs_Mouse1.29741508
89GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.29533703
90CMYC_18555785_Chip-Seq_ESCs_Mouse1.29253186
91NANOG_18555785_Chip-Seq_ESCs_Mouse1.28955912
92TAL1_26923725_Chip-Seq_HPCs_Mouse1.28110943
93PADI4_21655091_ChIP-ChIP_MCF-7_Human1.27512659
94POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.26964598
95FOXP3_21729870_ChIP-Seq_TREG_Human1.26719182
96EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.26695231
97VDR_23849224_ChIP-Seq_CD4+_Human1.26026090
98RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.24416645
99TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.23775966
100NRF2_20460467_ChIP-Seq_MEFs_Mouse1.22484332
101NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.22484332
102SUZ12_18555785_Chip-Seq_ESCs_Mouse1.22009972
103FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.21972821
104MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.21923898
105YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.21205027
106DROSHA_22980978_ChIP-Seq_HELA_Human1.20906814
107BMI1_23680149_ChIP-Seq_NPCS_Mouse1.20222312
108RNF2_27304074_Chip-Seq_NSC_Mouse1.20110484
109STAT3_23295773_ChIP-Seq_U87_Human1.20092895
110E2F1_21310950_ChIP-Seq_MCF-7_Human1.20078749
111P300_18555785_Chip-Seq_ESCs_Mouse1.19876246
112NACC1_18358816_ChIP-ChIP_MESCs_Mouse1.19550303
113SOX9_26525672_Chip-Seq_Limbbuds_Mouse1.19307226
114ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.19066380
115MYC_19030024_ChIP-ChIP_MESCs_Mouse1.18922530
116FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse1.18560204
117RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.18557200
118TTF2_22483619_ChIP-Seq_HELA_Human1.15389926
119EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.14487790
120PCGF2_27294783_Chip-Seq_ESCs_Mouse1.13199645
121TOP2B_26459242_ChIP-Seq_MCF-7_Human1.12947798
122LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse1.12362937
123PCGF2_27294783_Chip-Seq_NPCs_Mouse1.12224971
124MYC_19079543_ChIP-ChIP_MESCs_Mouse1.12193944
125NELFA_20434984_ChIP-Seq_ESCs_Mouse1.11770734
126ETS1_20019798_ChIP-Seq_JURKAT_Human1.11548283
127EP300_21415370_ChIP-Seq_HL-1_Mouse1.11187577
128P53_22127205_ChIP-Seq_FIBROBLAST_Human1.10308427
129TCF4_23295773_ChIP-Seq_U87_Human1.09101588
130FLI1_27457419_Chip-Seq_LIVER_Mouse1.07639640
131LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.07352645
132PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.07221221
133HTT_18923047_ChIP-ChIP_STHdh_Human1.07052216
134UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.06404580
135NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.05977741
136CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.05599462
137PRDM14_20953172_ChIP-Seq_ESCs_Human1.05426708
138GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.05231694
139HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.04789581
140SMAD4_21799915_ChIP-Seq_A2780_Human1.04781621
141IRF1_19129219_ChIP-ChIP_H3396_Human1.04589351
142P53_22387025_ChIP-Seq_ESCs_Mouse1.03915647
143EZH2_27294783_Chip-Seq_NPCs_Mouse1.03453612
144SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.03431650
145MYCN_18555785_ChIP-Seq_MESCs_Mouse1.02161740
146MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.01831530
147TCF3_18692474_ChIP-Seq_MESCs_Mouse1.01716424
148EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse1.01209706
149TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.01009201
150CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human1.00315771
151NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human0.99804202
152EWS_26573619_Chip-Seq_HEK293_Human0.99182097
153E2F1_18555785_Chip-Seq_ESCs_Mouse0.98860334
154EOMES_21245162_ChIP-Seq_HESCs_Human0.97341653
155ZNF217_24962896_ChIP-Seq_MCF-7_Human0.97311571
156TRIM28_17542650_ChIP-ChIP_NTERA2_Human0.97202723
157TCF3_18692474_ChIP-Seq_MEFs_Mouse0.96919467
158KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse0.95427958
159TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human0.95127522
160RUNX2_22187159_ChIP-Seq_PCA_Human0.94541006
161RUNX1_27457419_Chip-Seq_LIVER_Mouse0.94163295
162MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.93623094
163NR3C1_21868756_ChIP-Seq_MCF10A_Human0.93266323
164TBL1_22424771_ChIP-Seq_293T_Human0.92868571
165POU5F1_18555785_ChIP-Seq_MESCs_Mouse0.91912694
166XRN2_22483619_ChIP-Seq_HELA_Human0.91761359
167ASH2L_23239880_ChIP-Seq_MESCs_Mouse0.91358710
168SOX9_26525672_Chip-Seq_HEART_Mouse0.91271048
169REST_18959480_ChIP-ChIP_MESCs_Mouse0.90925331

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0000920_abnormal_myelination6.04286035
2MP0006292_abnormal_olfactory_placode4.84029301
3MP0003880_abnormal_central_pattern4.11566598
4MP0003690_abnormal_glial_cell3.42240089
5MP0004270_analgesia3.40645443
6MP0003950_abnormal_plasma_membrane3.38652969
7MP0004742_abnormal_vestibular_system3.04434698
8MP0003787_abnormal_imprinting3.01724299
9MP0003329_amyloid_beta_deposits2.96648555
10MP0004885_abnormal_endolymph2.93865615
11MP0003136_yellow_coat_color2.92952028
12MP0008877_abnormal_DNA_methylation2.74791926
13MP0003890_abnormal_embryonic-extraembry2.72591029
14MP0008789_abnormal_olfactory_epithelium2.66247359
15MP0001905_abnormal_dopamine_level2.58693562
16MP0001293_anophthalmia2.56490302
17MP0001485_abnormal_pinna_reflex2.55746406
18MP0005499_abnormal_olfactory_system2.53331083
19MP0005394_taste/olfaction_phenotype2.53331083
20MP0001529_abnormal_vocalization2.49916620
21MP0005409_darkened_coat_color2.49246176
22MP0003634_abnormal_glial_cell2.46402928
23MP0005410_abnormal_fertilization2.37785845
24MP0001486_abnormal_startle_reflex2.36848285
25MP0002272_abnormal_nervous_system2.35136556
26MP0000778_abnormal_nervous_system2.33280116
27MP0002653_abnormal_ependyma_morphology2.22697673
28MP0005171_absent_coat_pigmentation2.22199944
29MP0001188_hyperpigmentation2.21384336
30MP0004142_abnormal_muscle_tone2.18905115
31MP0004133_heterotaxia2.18722977
32MP0005451_abnormal_body_composition2.00247120
33MP0002064_seizures1.99773989
34MP0003632_abnormal_nervous_system1.97346316
35MP0000462_abnormal_digestive_system1.94458011
36MP0003693_abnormal_embryo_hatching1.94224530
37MP0002229_neurodegeneration1.92000992
38MP0003121_genomic_imprinting1.90061520
39MP0006276_abnormal_autonomic_nervous1.89846608
40MP0001984_abnormal_olfaction1.85816561
41MP0010678_abnormal_skin_adnexa1.85322076
42MP0010094_abnormal_chromosome_stability1.81873400
43MP0008058_abnormal_DNA_repair1.79851400
44MP0003122_maternal_imprinting1.77654309
45MP0009046_muscle_twitch1.72310837
46MP0004134_abnormal_chest_morphology1.69678011
47MP0000383_abnormal_hair_follicle1.69617865
48MP0005423_abnormal_somatic_nervous1.60979742
49MP0000604_amyloidosis1.60619046
50MP0004957_abnormal_blastocyst_morpholog1.60084199
51MP0004381_abnormal_hair_follicle1.58728923
52MP0008932_abnormal_embryonic_tissue1.55146780
53MP0001286_abnormal_eye_development1.51986697
54MP0003119_abnormal_digestive_system1.51616168
55MP0002734_abnormal_mechanical_nocicepti1.50517604
56MP0009745_abnormal_behavioral_response1.48082300
57MP0005551_abnormal_eye_electrophysiolog1.47667634
58MP0003635_abnormal_synaptic_transmissio1.41771372
59MP0000049_abnormal_middle_ear1.40256585
60MP0001963_abnormal_hearing_physiology1.39684774
61MP0003567_abnormal_fetal_cardiomyocyte1.39658483
62MP0001661_extended_life_span1.36167967
63MP0004859_abnormal_synaptic_plasticity1.36158830
64MP0002882_abnormal_neuron_morphology1.36046343
65MP0000955_abnormal_spinal_cord1.35719304
66MP0002638_abnormal_pupillary_reflex1.35689056
67MP0004147_increased_porphyrin_level1.34092134
68MP0002233_abnormal_nose_morphology1.33041403
69MP0005623_abnormal_meninges_morphology1.32522489
70MP0002822_catalepsy1.32346574
71MP0003631_nervous_system_phenotype1.29642895
72MP0008260_abnormal_autophagy1.28773402
73MP0003111_abnormal_nucleus_morphology1.27450194
74MP0003123_paternal_imprinting1.27322901
75MP0001440_abnormal_grooming_behavior1.24669026
76MP0001851_eye_inflammation1.24116396
77MP0002752_abnormal_somatic_nervous1.23996027
78MP0003077_abnormal_cell_cycle1.23669853
79MP0002697_abnormal_eye_size1.23653675
80MP0000537_abnormal_urethra_morphology1.22050554
81MP0002102_abnormal_ear_morphology1.21526218
82MP0003938_abnormal_ear_development1.20231557
83MP0002066_abnormal_motor_capabilities/c1.18305872
84MP0003937_abnormal_limbs/digits/tail_de1.16743487
85MP0002751_abnormal_autonomic_nervous1.13913363
86MP0004924_abnormal_behavior1.13273493
87MP0005386_behavior/neurological_phenoty1.13273493
88MP0002572_abnormal_emotion/affect_behav1.12861297
89MP0009379_abnormal_foot_pigmentation1.12811704
90MP0002084_abnormal_developmental_patter1.12016371
91MP0001299_abnormal_eye_distance/1.11519075
92MP0005195_abnormal_posterior_eye1.10325925
93MP0002067_abnormal_sensory_capabilities1.10157330
94MP0005408_hypopigmentation1.09289545
95MP0003718_maternal_effect1.08559862
96MP0002234_abnormal_pharynx_morphology1.07076606
97MP0004043_abnormal_pH_regulation1.04100893
98MP0003806_abnormal_nucleotide_metabolis1.03220549
99MP0004811_abnormal_neuron_physiology1.03003903
100MP0000747_muscle_weakness1.02675273
101MP0000566_synostosis1.02504828
102MP0008569_lethality_at_weaning1.01577871
103MP0004185_abnormal_adipocyte_glucose1.00017501
104MP0002085_abnormal_embryonic_tissue0.99752653
105MP0003633_abnormal_nervous_system0.98472451
106MP0009672_abnormal_birth_weight0.97898056
107MP0000647_abnormal_sebaceous_gland0.97300712
108MP0002111_abnormal_tail_morphology0.97231048
109MP0000428_abnormal_craniofacial_morphol0.96494514
110MP0001970_abnormal_pain_threshold0.95647967
111MP0003941_abnormal_skin_development0.95385609
112MP0002092_abnormal_eye_morphology0.95380476
113MP0001348_abnormal_lacrimal_gland0.93322694
114MP0002063_abnormal_learning/memory/cond0.92733314
115MP0005391_vision/eye_phenotype0.92373076
116MP0001346_abnormal_lacrimal_gland0.91442718
117MP0001730_embryonic_growth_arrest0.91268194
118MP0010030_abnormal_orbit_morphology0.90964326
119MP0004145_abnormal_muscle_electrophysio0.88725087
120MP0000026_abnormal_inner_ear0.88679072
121MP0002152_abnormal_brain_morphology0.86116973
122MP0003195_calcinosis0.85193107
123MP0000467_abnormal_esophagus_morphology0.83028588
124MP0004197_abnormal_fetal_growth/weight/0.82944733
125MP0002733_abnormal_thermal_nociception0.82732742
126MP0008007_abnormal_cellular_replicative0.81720143
127MP0002163_abnormal_gland_morphology0.81385332
128MP0002938_white_spotting0.80953612
129MP0001672_abnormal_embryogenesis/_devel0.80807396
130MP0005380_embryogenesis_phenotype0.80807396
131MP0002736_abnormal_nociception_after0.80758715
132MP0005058_abnormal_lysosome_morphology0.80180012
133MP0009703_decreased_birth_body0.79592516
134MP0002081_perinatal_lethality0.79376580
135MP0001177_atelectasis0.79143105
136MP0000762_abnormal_tongue_morphology0.78883059
137MP0003755_abnormal_palate_morphology0.78590572
138MP0002160_abnormal_reproductive_system0.77599073
139MP0001697_abnormal_embryo_size0.76825588
140MP0002295_abnormal_pulmonary_circulatio0.76483736
141MP0000465_gastrointestinal_hemorrhage0.75155666
142MP0006072_abnormal_retinal_apoptosis0.74228475
143MP0005253_abnormal_eye_physiology0.72593250
144MP0006082_CNS_inflammation0.71298339
145MP0002133_abnormal_respiratory_system0.69149572
146MP0005388_respiratory_system_phenotype0.69149572
147MP0000631_abnormal_neuroendocrine_gland0.68492100
148MP0003698_abnormal_male_reproductive0.68432745
149MP0001502_abnormal_circadian_rhythm0.67195399
150MP0008057_abnormal_DNA_replication0.67036611
151MP0001727_abnormal_embryo_implantation0.66586461
152MP0009384_cardiac_valve_regurgitation0.64770893
153MP0009250_abnormal_appendicular_skeleto0.63977930
154MP0001340_abnormal_eyelid_morphology0.62234199
155MP0002090_abnormal_vision0.60461198
156MP0002735_abnormal_chemical_nociception0.58672571
157MP0002184_abnormal_innervation0.57448410
158MP0002557_abnormal_social/conspecific_i0.57127115
159MP0001968_abnormal_touch/_nociception0.56502235
160MP0003861_abnormal_nervous_system0.55404481

Predicted human phenotypes

RankGene SetZ-score
1Degeneration of the lateral corticospinal tracts (HP:0002314)7.32633580
2Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)7.32633580
3Neurofibrillary tangles (HP:0002185)6.29590869
4Sensory axonal neuropathy (HP:0003390)5.59594366
5Abnormality of the corticospinal tract (HP:0002492)5.38806435
6Parakeratosis (HP:0001036)5.27615051
7Peripheral hypomyelination (HP:0007182)4.57640504
8Cerebral inclusion bodies (HP:0100314)4.44287929
9Congenital nonbullous ichthyosiform erythroderma (HP:0007479)3.95678974
10Septo-optic dysplasia (HP:0100842)3.89824228
11Colon cancer (HP:0003003)3.83514731
12Insidious onset (HP:0003587)3.73295611
13Termporal pattern (HP:0011008)3.73295611
14Spastic gait (HP:0002064)3.61400955
15Akinesia (HP:0002304)3.46626433
16Onion bulb formation (HP:0003383)3.35603904
17Supranuclear gaze palsy (HP:0000605)3.30318031
18Hepatoblastoma (HP:0002884)3.23412281
19Abnormality of the labia minora (HP:0012880)3.20756470
20Retinal dysplasia (HP:0007973)3.17889991
21Respiratory insufficiency due to defective ciliary clearance (HP:0200073)3.17533626
22Intention tremor (HP:0002080)3.05757376
23Abnormal auditory evoked potentials (HP:0006958)3.04586916
24Abnormality of glycolysis (HP:0004366)3.04192661
25Increased serum pyruvate (HP:0003542)3.04192661
26Dysmetria (HP:0001310)2.96160368
27Cerebral hypomyelination (HP:0006808)2.92272249
28Alacrima (HP:0000522)2.86502358
29Autoamputation (HP:0001218)2.81837379
30Hypoplastic pelvis (HP:0008839)2.80990904
31Scanning speech (HP:0002168)2.79723039
32Congenital ichthyosiform erythroderma (HP:0007431)2.78415370
33Abnormality of abdominal situs (HP:0011620)2.75277199
34Abdominal situs inversus (HP:0003363)2.75277199
35Thickened helices (HP:0000391)2.72200738
36Absent/shortened dynein arms (HP:0200106)2.71075091
37Dynein arm defect of respiratory motile cilia (HP:0012255)2.71075091
38Premature skin wrinkling (HP:0100678)2.67946272
39Leukodystrophy (HP:0002415)2.67386055
40Anteriorly placed anus (HP:0001545)2.64587929
41Partial agenesis of the corpus callosum (HP:0001338)2.63180693
42Cerebral hemorrhage (HP:0001342)2.62159046
43Absent septum pellucidum (HP:0001331)2.60055545
44Stenosis of the external auditory canal (HP:0000402)2.58461055
45Slow saccadic eye movements (HP:0000514)2.56858833
46Supernumerary spleens (HP:0009799)2.55578777
47Spastic paraparesis (HP:0002313)2.53373011
48Stridor (HP:0010307)2.53326510
49Nephroblastoma (Wilms tumor) (HP:0002667)2.52409152
50Neoplasm of the adrenal cortex (HP:0100641)2.51920590
51Adrenal hypoplasia (HP:0000835)2.44210613
52Maternal diabetes (HP:0009800)2.41971765
53Clumsiness (HP:0002312)2.38702379
54Embryonal renal neoplasm (HP:0011794)2.35705804
55Medial flaring of the eyebrow (HP:0010747)2.32142825
56Nephronophthisis (HP:0000090)2.31427766
57Pancreatic fibrosis (HP:0100732)2.30089381
58Decreased lacrimation (HP:0000633)2.29658638
59Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)2.28862643
60Abnormal respiratory motile cilium physiology (HP:0012261)2.28272307
61Abnormality of the phalanges of the 2nd finger (HP:0009541)2.24349937
62Coronal craniosynostosis (HP:0004440)2.23780510
63White forelock (HP:0002211)2.23178611
64Patchy hypopigmentation of hair (HP:0011365)2.22618676
65Cupped ear (HP:0000378)2.22138824
66Abnormal ciliary motility (HP:0012262)2.21343410
67Abnormality of the septum pellucidum (HP:0007375)2.19963521
68Hyperglycinemia (HP:0002154)2.19946788
69Hepatosplenomegaly (HP:0001433)2.19396407
70Increased circulating renin level (HP:0000848)2.18435678
71Optic nerve hypoplasia (HP:0000609)2.17925581
72Reticulocytopenia (HP:0001896)2.17010437
73Genital tract atresia (HP:0001827)2.15792567
74Chin dimple (HP:0010751)2.13978166
75Gait imbalance (HP:0002141)2.13929726
76Hypomagnesemia (HP:0002917)2.11958116
77Synostosis involving the elbow (HP:0003938)2.10433103
78Humeroradial synostosis (HP:0003041)2.10433103
79True hermaphroditism (HP:0010459)2.07847014
80Infantile muscular hypotonia (HP:0008947)2.07608080
81Morphological abnormality of the inner ear (HP:0011390)2.07083914
82Congenital primary aphakia (HP:0007707)2.06806430
83Aplasia/Hypoplasia of the optic nerve (HP:0008058)2.05284529
84Pancreatic cysts (HP:0001737)2.04750198
85Metabolic alkalosis (HP:0200114)2.04741463
86Drooling (HP:0002307)2.04354456
87Barrel-shaped chest (HP:0001552)2.03969214
88Cortical dysplasia (HP:0002539)2.03944678
89Split foot (HP:0001839)2.02665966
90Ankle clonus (HP:0011448)2.01716279
91Abnormal lung lobation (HP:0002101)2.00061917
92Renal Fanconi syndrome (HP:0001994)1.99756087
93Chromosomal breakage induced by crosslinking agents (HP:0003221)1.99685254
94Lower limb muscle weakness (HP:0007340)1.99423836
95Segmental peripheral demyelination/remyelination (HP:0003481)1.96772799
96Abnormality of midbrain morphology (HP:0002418)1.96743875
97Molar tooth sign on MRI (HP:0002419)1.96743875
98Esophageal atresia (HP:0002032)1.96637720
99Chromsome breakage (HP:0040012)1.95873942
100Progressive cerebellar ataxia (HP:0002073)1.95865980
101Widely spaced teeth (HP:0000687)1.95463626
102Myokymia (HP:0002411)1.95308051
103Spastic tetraparesis (HP:0001285)1.93649573
104Pheochromocytoma (HP:0002666)1.92806214
105Generalized myoclonic seizures (HP:0002123)1.92237341
106Chronic bronchitis (HP:0004469)1.91966913
107Type II lissencephaly (HP:0007260)1.91774693
108Hypoplasia of the iris (HP:0007676)1.91686765
109Diminished movement (HP:0002374)1.91658796
110Anophthalmia (HP:0000528)1.91370999
111CNS hypomyelination (HP:0003429)1.90595139
112Growth hormone deficiency (HP:0000824)1.90204560
113Abnormal hair whorl (HP:0010721)1.89752564
114Meckel diverticulum (HP:0002245)1.89490135
115Nephrogenic diabetes insipidus (HP:0009806)1.88849527
116Poor coordination (HP:0002370)1.88137008
117Cerebellar dysplasia (HP:0007033)1.87169678
118Aplasia/Hypoplasia of the sternum (HP:0006714)1.86775823
119Specific learning disability (HP:0001328)1.86560031
120Atonic seizures (HP:0010819)1.86093717
121Abolished electroretinogram (ERG) (HP:0000550)1.86073445
122Chronic hepatic failure (HP:0100626)1.86038586
123Anomalous pulmonary venous return (HP:0010772)1.85943183
124Hypokalemic alkalosis (HP:0001949)1.85240012
125Shoulder girdle muscle weakness (HP:0003547)1.84384046
126Relative macrocephaly (HP:0004482)1.83785866
127Morphological abnormality of the pyramidal tract (HP:0002062)1.82523704
128Abnormal respiratory epithelium morphology (HP:0012253)1.82016187
129Abnormal respiratory motile cilium morphology (HP:0005938)1.82016187
130Excessive salivation (HP:0003781)1.81536264
131Horseshoe kidney (HP:0000085)1.80995673
132Birth length less than 3rd percentile (HP:0003561)1.80984653
133Medulloblastoma (HP:0002885)1.80700917
134Abnormality of chromosome stability (HP:0003220)1.80570868
135Small epiphyses (HP:0010585)1.80564903
136Anencephaly (HP:0002323)1.80250425
137Dandy-Walker malformation (HP:0001305)1.79490443
138Abnormality of the renal medulla (HP:0100957)1.78913187
139Broad foot (HP:0001769)1.77439119
140Poor speech (HP:0002465)1.77286941
141Impaired vibration sensation in the lower limbs (HP:0002166)1.76873302
142Urinary incontinence (HP:0000020)1.76863759
143Erythroderma (HP:0001019)1.76686201
144Tubulointerstitial nephritis (HP:0001970)1.76180882
145Oligodactyly (hands) (HP:0001180)1.75993011
146Rhabdomyosarcoma (HP:0002859)1.75967007
147Partial duplication of thumb phalanx (HP:0009944)1.75307301
148Breast aplasia (HP:0100783)1.74950852
149Abnormality of the ileum (HP:0001549)1.74938621
150Bile duct proliferation (HP:0001408)1.74191325
151Abnormal biliary tract physiology (HP:0012439)1.74191325
152Methylmalonic acidemia (HP:0002912)1.74045866
153Bowel incontinence (HP:0002607)1.72816887
154Steppage gait (HP:0003376)1.72800496
155Papillary thyroid carcinoma (HP:0002895)1.72630107
156Rib fusion (HP:0000902)1.72586823
157Aplasia/Hypoplasia of the uvula (HP:0010293)1.71528967
158Broad-based gait (HP:0002136)1.71110264
159Sclerocornea (HP:0000647)1.70739918
160Optic nerve coloboma (HP:0000588)1.70216483
161Aplasia of the phalanges of the hand (HP:0009802)1.70142653
162Aplasia involving bones of the extremities (HP:0009825)1.70142653
163Aplasia involving bones of the upper limbs (HP:0009823)1.70142653
1643-Methylglutaconic aciduria (HP:0003535)1.70107628
165Focal motor seizures (HP:0011153)1.69831860
166Absent thumb (HP:0009777)1.69815880
167Vaginal atresia (HP:0000148)1.69686401
168Abnormal large intestine physiology (HP:0012700)1.69596849
169Holoprosencephaly (HP:0001360)1.69507284
170Neuroendocrine neoplasm (HP:0100634)1.69396322
171Rimmed vacuoles (HP:0003805)1.69229062
172Lissencephaly (HP:0001339)1.69072778
173Gowers sign (HP:0003391)1.68828890
174Spastic diplegia (HP:0001264)1.68453673
175Myelomeningocele (HP:0002475)1.68419753
176Carpal bone hypoplasia (HP:0001498)1.68056850
177Aplasia/Hypoplasia of the spleen (HP:0010451)1.67282085
178Asplenia (HP:0001746)1.64292488
179Aqueductal stenosis (HP:0002410)1.64290209
180Pelvic girdle muscle weakness (HP:0003749)1.64189963
181Triphalangeal thumb (HP:0001199)1.63759569
182Aplasia/Hypoplasia of the breasts (HP:0010311)1.62666270
183Intestinal atresia (HP:0011100)1.61710731
184Diastasis recti (HP:0001540)1.61333832
185Urinary urgency (HP:0000012)1.61020504
186Abnormality of the musculature of the pelvis (HP:0001469)1.60828033
187Abnormality of the hip-girdle musculature (HP:0001445)1.60828033
188Primary amenorrhea (HP:0000786)1.60245495
189Preaxial hand polydactyly (HP:0001177)1.58145779

Predicted kinase interactions (KEA)

RankGene SetZ-score
1STK396.76080679
2OXSR14.75763080
3EPHB13.77607244
4BRSK23.26105145
5MKNK23.16202724
6TNIK2.82632559
7CDK192.70663878
8CDC72.63207192
9WNK42.58002110
10MAP3K42.55698061
11BCR2.53213684
12WEE12.49342097
13BRD42.48504996
14PBK2.45402279
15SRPK12.41716439
16PKN12.36643416
17DYRK32.28094213
18PNCK2.15713363
19WNK32.11972760
20MET2.01898870
21TAF12.00623968
22WNK12.00262926
23MAPKAPK51.98995736
24EIF2AK31.97858655
25CSNK1G31.89218707
26ICK1.87926796
27FGFR21.84468732
28LIMK11.77751124
29ZAK1.77611351
30CSNK1A1L1.75574871
31MAP2K71.74503784
32NEK61.72713069
33CLK11.68908654
34UHMK11.59716278
35PINK11.57195690
36TRIM281.56077251
37MST41.54962680
38FGR1.52335354
39CSNK1G11.50902714
40MAP3K101.49056034
41TYRO31.43926193
42VRK11.40163690
43PRPF4B1.39658733
44ROCK21.38726749
45CSNK1G21.38628864
46PLK41.34825030
47PLK31.34489042
48NTRK11.32412906
49TTK1.30956365
50CAMKK21.29832054
51MAP3K91.29342507
52PAK61.26198019
53CAMK2B1.25157203
54TSSK61.22605911
55RPS6KA41.20042447
56CASK1.18678223
57ERBB31.16299424
58MINK11.15256252
59PLK11.11005768
60IRAK21.10811306
61EPHA41.08954125
62VRK21.07155457
63BRSK11.07080112
64CAMK2D1.05615706
65TESK21.04866502
66MAPK151.02337370
67IRAK10.96500885
68ERBB40.96198416
69PRKCQ0.95639053
70DYRK20.95466848
71FES0.95303389
72CHEK20.95239220
73BMPR1B0.95189246
74BCKDK0.88307540
75MUSK0.87955295
76PAK30.86622354
77STK240.86053224
78DYRK1B0.85439791
79MARK10.85244089
80ARAF0.83735313
81MAP3K130.81448698
82MARK20.81023871
83CDK140.79046013
84STK30.78659605
85PRKCG0.70750206
86CAMK2G0.70466604
87SGK2230.70083352
88SGK4940.70083352
89ATR0.70003439
90CAMK2A0.69539222
91BRAF0.69196734
92NTRK20.68821109
93BUB10.67241429
94CDK150.67154388
95EIF2AK20.66717748
96MAP4K20.66131593
97PIM10.65173601
98CDK50.64575170
99ATM0.63873452
100PDPK10.62907220
101CDK180.61362058
102CDK11A0.60814468
103MAP2K40.60187721
104NEK10.58839462
105FYN0.57968753
106NEK20.57483019
107CAMK1D0.57309667
108PLK20.56532869
109AURKA0.55969696
110RPS6KA50.55177326
111CAMKK10.54007780
112KSR10.53864330
113TIE10.52863453
114PRKD10.52559349
115CSNK1D0.52059662
116PASK0.50635345
117CSK0.50090947
118CAMK10.48211397
119STK38L0.47738535
120LATS10.47609243
121STK110.46673215
122PDGFRB0.46414809
123PRKCE0.46207443
124ALK0.45510743
125CSNK1E0.44331208
126CAMK40.44161859
127IRAK40.43697359
128TEC0.43590532
129CDK20.42951028
130PRKG10.42311358
131BLK0.42238163
132MAPK130.41664964
133CDK60.41628269
134MELK0.40946274
135KSR20.39979546
136EIF2AK10.39539208
137BMPR20.38869546
138AURKB0.38666265
139ITK0.37414076
140GSK3A0.36848217
141CAMK1G0.36825866
142CDK10.36269210
143MOS0.36194860
144CHEK10.36150820
145TRPM70.34931556
146LCK0.33530173
147PAK10.32927338
148INSR0.32594513
149HIPK20.32141311
150PDK10.31713728
151ADRBK20.31420612
152CSNK1A10.31379846
153MKNK10.31116355
154PRKACB0.28761282
155ABL10.28151425
156STK160.27365564
157PIK3CA0.27111496
158PHKG10.26430891
159PHKG20.26430891
160DYRK1A0.25649621
161MAP2K20.25113511
162CSF1R0.24335656
163NUAK10.23219969
164MAPK70.22342866
165CDK30.20020595
166DMPK0.19889961

Predicted pathways (KEGG)

RankGene SetZ-score
1Terpenoid backbone biosynthesis_Homo sapiens_hsa009005.68974095
2Steroid biosynthesis_Homo sapiens_hsa001004.84277708
3Fatty acid elongation_Homo sapiens_hsa000624.38275380
4Synthesis and degradation of ketone bodies_Homo sapiens_hsa000723.59662588
5Ether lipid metabolism_Homo sapiens_hsa005653.52523297
6Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005632.92658796
7Caffeine metabolism_Homo sapiens_hsa002322.75025056
8Spliceosome_Homo sapiens_hsa030402.57190279
9RNA degradation_Homo sapiens_hsa030182.41763939
10Fanconi anemia pathway_Homo sapiens_hsa034602.32651858
11Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010402.29235888
12Non-homologous end-joining_Homo sapiens_hsa034502.29108964
13RNA transport_Homo sapiens_hsa030132.23429424
14Protein export_Homo sapiens_hsa030602.22949453
15Mismatch repair_Homo sapiens_hsa034302.21264249
16Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.20213105
17Cell cycle_Homo sapiens_hsa041102.15760121
18Sphingolipid metabolism_Homo sapiens_hsa006002.13625924
19mRNA surveillance pathway_Homo sapiens_hsa030152.11286478
20RNA polymerase_Homo sapiens_hsa030202.11029128
21Oxidative phosphorylation_Homo sapiens_hsa001902.07421668
22Sulfur metabolism_Homo sapiens_hsa009202.02102383
23DNA replication_Homo sapiens_hsa030301.97035032
24Ribosome_Homo sapiens_hsa030101.95092379
25Axon guidance_Homo sapiens_hsa043601.92144440
26Homologous recombination_Homo sapiens_hsa034401.83874835
27Selenocompound metabolism_Homo sapiens_hsa004501.73003452
28Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.67731292
29Linoleic acid metabolism_Homo sapiens_hsa005911.66186941
30Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.65859298
31Base excision repair_Homo sapiens_hsa034101.65516501
32Vitamin B6 metabolism_Homo sapiens_hsa007501.59972450
33Cell adhesion molecules (CAMs)_Homo sapiens_hsa045141.59900562
34Histidine metabolism_Homo sapiens_hsa003401.58298364
35p53 signaling pathway_Homo sapiens_hsa041151.56305054
36Cysteine and methionine metabolism_Homo sapiens_hsa002701.54737956
37alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.47858080
38Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045501.46811574
39Basal cell carcinoma_Homo sapiens_hsa052171.45028004
40Alzheimers disease_Homo sapiens_hsa050101.44511634
41Parkinsons disease_Homo sapiens_hsa050121.41446656
42Hippo signaling pathway_Homo sapiens_hsa043901.40046029
43Butanoate metabolism_Homo sapiens_hsa006501.36553525
44Renal cell carcinoma_Homo sapiens_hsa052111.36192890
45Serotonergic synapse_Homo sapiens_hsa047261.22894922
46Oocyte meiosis_Homo sapiens_hsa041141.18083045
47Glutamatergic synapse_Homo sapiens_hsa047241.14120640
48Wnt signaling pathway_Homo sapiens_hsa043101.13292733
49Long-term depression_Homo sapiens_hsa047301.12679224
50Nucleotide excision repair_Homo sapiens_hsa034201.12137940
51Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002501.09985753
52Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.06020376
53Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.03525459
54Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.02330281
55Sphingolipid signaling pathway_Homo sapiens_hsa040710.98102051
56Dorso-ventral axis formation_Homo sapiens_hsa043200.96310397
57Taste transduction_Homo sapiens_hsa047420.95057488
58GABAergic synapse_Homo sapiens_hsa047270.91530326
59Tight junction_Homo sapiens_hsa045300.90504932
60Autoimmune thyroid disease_Homo sapiens_hsa053200.89176695
61Arginine and proline metabolism_Homo sapiens_hsa003300.86449265
62Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.86373802
63Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.83964270
64Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.83383014
65Phospholipase D signaling pathway_Homo sapiens_hsa040720.80684750
66SNARE interactions in vesicular transport_Homo sapiens_hsa041300.80514681
67Vibrio cholerae infection_Homo sapiens_hsa051100.80022273
68Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.79716681
69Circadian rhythm_Homo sapiens_hsa047100.79529805
70Glutathione metabolism_Homo sapiens_hsa004800.78797628
71Nitrogen metabolism_Homo sapiens_hsa009100.78769325
72Purine metabolism_Homo sapiens_hsa002300.78098682
73Colorectal cancer_Homo sapiens_hsa052100.78057150
74Huntingtons disease_Homo sapiens_hsa050160.77973107
75Morphine addiction_Homo sapiens_hsa050320.77776440
76Ovarian steroidogenesis_Homo sapiens_hsa049130.77415725
77Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.76568913
78Rheumatoid arthritis_Homo sapiens_hsa053230.76270815
79Collecting duct acid secretion_Homo sapiens_hsa049660.75275891
80Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.75170432
81Arachidonic acid metabolism_Homo sapiens_hsa005900.75120126
82Ras signaling pathway_Homo sapiens_hsa040140.74022495
83Lysine degradation_Homo sapiens_hsa003100.71829856
84Endocytosis_Homo sapiens_hsa041440.70108115
85Malaria_Homo sapiens_hsa051440.69522521
86Olfactory transduction_Homo sapiens_hsa047400.69220655
87TGF-beta signaling pathway_Homo sapiens_hsa043500.67779733
88Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.67337939
89ErbB signaling pathway_Homo sapiens_hsa040120.66875927
90Long-term potentiation_Homo sapiens_hsa047200.66668454
91Phototransduction_Homo sapiens_hsa047440.66034779
92Pyrimidine metabolism_Homo sapiens_hsa002400.65730624
93beta-Alanine metabolism_Homo sapiens_hsa004100.64638733
94Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.64584929
95Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.63757731
96Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.63393792
97Systemic lupus erythematosus_Homo sapiens_hsa053220.62291412
98Amphetamine addiction_Homo sapiens_hsa050310.61255553
99Cardiac muscle contraction_Homo sapiens_hsa042600.60367590
100Glycerophospholipid metabolism_Homo sapiens_hsa005640.60329944
101Steroid hormone biosynthesis_Homo sapiens_hsa001400.59254437
102Choline metabolism in cancer_Homo sapiens_hsa052310.58860391
103Propanoate metabolism_Homo sapiens_hsa006400.58543991
104Vascular smooth muscle contraction_Homo sapiens_hsa042700.58521583
105Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.57977237
106Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.57851221
107Fatty acid metabolism_Homo sapiens_hsa012120.56855825
108Oxytocin signaling pathway_Homo sapiens_hsa049210.56414932
109Melanogenesis_Homo sapiens_hsa049160.55127614
110Cocaine addiction_Homo sapiens_hsa050300.51929415
111Melanoma_Homo sapiens_hsa052180.51271217
112Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.49779927
113Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.49633483
114MicroRNAs in cancer_Homo sapiens_hsa052060.49340433
115Thyroid cancer_Homo sapiens_hsa052160.49094022
116Phagosome_Homo sapiens_hsa041450.49051399
117Regulation of actin cytoskeleton_Homo sapiens_hsa048100.48905993
118Transcriptional misregulation in cancer_Homo sapiens_hsa052020.46753707
119Cholinergic synapse_Homo sapiens_hsa047250.46086114
120Basal transcription factors_Homo sapiens_hsa030220.46044313
121Pancreatic secretion_Homo sapiens_hsa049720.45937569
122Peroxisome_Homo sapiens_hsa041460.45407913
123Fatty acid biosynthesis_Homo sapiens_hsa000610.45142562
124Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.44296118
125Salivary secretion_Homo sapiens_hsa049700.44018299
126Dopaminergic synapse_Homo sapiens_hsa047280.42093841
127Endometrial cancer_Homo sapiens_hsa052130.41590084
128Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.40860341
129Insulin secretion_Homo sapiens_hsa049110.40412363
130Nicotine addiction_Homo sapiens_hsa050330.39966961
131Hedgehog signaling pathway_Homo sapiens_hsa043400.38842903
132Inositol phosphate metabolism_Homo sapiens_hsa005620.38686978
133FoxO signaling pathway_Homo sapiens_hsa040680.38377709
134ECM-receptor interaction_Homo sapiens_hsa045120.37143288
135Metabolic pathways_Homo sapiens_hsa011000.36396115
136T cell receptor signaling pathway_Homo sapiens_hsa046600.35899614
137Adherens junction_Homo sapiens_hsa045200.35844104
138Lysosome_Homo sapiens_hsa041420.35697449
139Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.35099660
140Viral carcinogenesis_Homo sapiens_hsa052030.34940115
141Circadian entrainment_Homo sapiens_hsa047130.34691867
142B cell receptor signaling pathway_Homo sapiens_hsa046620.34541003
143Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.33321614
144Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.31671305
145Renin secretion_Homo sapiens_hsa049240.30810808
146MAPK signaling pathway_Homo sapiens_hsa040100.30769255
147Prion diseases_Homo sapiens_hsa050200.29876128
148Gastric acid secretion_Homo sapiens_hsa049710.29138230
149Gap junction_Homo sapiens_hsa045400.28534920
150Regulation of autophagy_Homo sapiens_hsa041400.27938529
151Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.27042844
152Mineral absorption_Homo sapiens_hsa049780.26645914
153Prostate cancer_Homo sapiens_hsa052150.26615172
154Chemokine signaling pathway_Homo sapiens_hsa040620.26287579
155Salmonella infection_Homo sapiens_hsa051320.26138201
156cAMP signaling pathway_Homo sapiens_hsa040240.24323717
157PI3K-Akt signaling pathway_Homo sapiens_hsa041510.24178775
158Alcoholism_Homo sapiens_hsa050340.24133889

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »