ABHD17C

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222)6.00652107
2L-phenylalanine catabolic process (GO:0006559)6.00652107
3erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221)5.95790721
4L-phenylalanine metabolic process (GO:0006558)5.95790721
5aromatic amino acid family catabolic process (GO:0009074)5.68596833
6desmosome organization (GO:0002934)5.44077321
7tryptophan catabolic process (GO:0006569)5.41255832
8indole-containing compound catabolic process (GO:0042436)5.41255832
9indolalkylamine catabolic process (GO:0046218)5.41255832
10cysteine metabolic process (GO:0006534)5.34485563
11kynurenine metabolic process (GO:0070189)5.24719784
12urea cycle (GO:0000050)5.23026092
13urea metabolic process (GO:0019627)5.23026092
14glyoxylate metabolic process (GO:0046487)5.17428490
15tryptophan metabolic process (GO:0006568)5.15023811
16triglyceride-rich lipoprotein particle remodeling (GO:0034370)5.11577840
17sulfur amino acid catabolic process (GO:0000098)4.88724116
18homocysteine metabolic process (GO:0050667)4.70999574
19nitrogen cycle metabolic process (GO:0071941)4.70023998
20lysine catabolic process (GO:0006554)4.68965371
21lysine metabolic process (GO:0006553)4.68965371
22alpha-linolenic acid metabolic process (GO:0036109)4.53614499
23serine family amino acid catabolic process (GO:0009071)4.47771455
24negative regulation of keratinocyte proliferation (GO:0010839)4.45866455
25peptidyl-glutamic acid carboxylation (GO:0017187)4.43836402
26protein carboxylation (GO:0018214)4.43836402
27bile acid biosynthetic process (GO:0006699)4.40155503
28negative regulation of cholesterol transport (GO:0032375)4.30992262
29negative regulation of sterol transport (GO:0032372)4.30992262
30intestinal epithelial cell development (GO:0060576)4.30295507
31drug catabolic process (GO:0042737)4.22075067
32fatty acid beta-oxidation using acyl-CoA oxidase (GO:0033540)4.21392997
33negative regulation of fibrinolysis (GO:0051918)4.20628080
34amino-acid betaine metabolic process (GO:0006577)4.20388238
35skin morphogenesis (GO:0043589)4.13641092
36high-density lipoprotein particle remodeling (GO:0034375)4.07409076
37drug transmembrane transport (GO:0006855)4.07376899
38regulation of triglyceride catabolic process (GO:0010896)4.06657831
39intestinal cholesterol absorption (GO:0030299)4.05270421
40cellular ketone body metabolic process (GO:0046950)4.05162267
41bundle of His cell to Purkinje myocyte communication (GO:0086069)4.01458586
42aromatic amino acid family metabolic process (GO:0009072)4.01395829
43urate metabolic process (GO:0046415)3.99919461
44bile acid metabolic process (GO:0008206)3.90983441
45regulation of fibrinolysis (GO:0051917)3.89920348
46complement activation, alternative pathway (GO:0006957)3.88276174
47flavonoid metabolic process (GO:0009812)3.87679981
48plasma lipoprotein particle clearance (GO:0034381)3.85844222
49cellular glucuronidation (GO:0052695)3.84752356
50serine family amino acid metabolic process (GO:0009069)3.83990402
51phospholipid efflux (GO:0033700)3.81779380
52hemidesmosome assembly (GO:0031581)3.79456599
53cellular modified amino acid catabolic process (GO:0042219)3.79373256
54regulation of protein activation cascade (GO:2000257)3.78706257
55alpha-amino acid catabolic process (GO:1901606)3.78633068
56triglyceride homeostasis (GO:0070328)3.75708258
57acylglycerol homeostasis (GO:0055090)3.75708258
58establishment of planar polarity (GO:0001736)3.71643096
59establishment of tissue polarity (GO:0007164)3.71643096
60bile acid and bile salt transport (GO:0015721)3.71240365
61intestinal absorption (GO:0050892)3.70907542
62indolalkylamine metabolic process (GO:0006586)3.69999161
63positive regulation of heterotypic cell-cell adhesion (GO:0034116)3.69891774
64drug transport (GO:0015893)3.67653828
65glycine metabolic process (GO:0006544)3.66863679
66reverse cholesterol transport (GO:0043691)3.63415491
67regulation of cholesterol homeostasis (GO:2000188)3.60876557
68regulation of cholesterol esterification (GO:0010872)3.60684776
69glutamate metabolic process (GO:0006536)3.60210478
70cellular biogenic amine catabolic process (GO:0042402)3.60035672
71amine catabolic process (GO:0009310)3.60035672
72keratinocyte proliferation (GO:0043616)3.58881568
73plasma lipoprotein particle remodeling (GO:0034369)3.58393416
74protein-lipid complex remodeling (GO:0034368)3.58393416
75macromolecular complex remodeling (GO:0034367)3.58393416
76regulation of keratinocyte proliferation (GO:0010837)3.56911746
77positive regulation of lipid catabolic process (GO:0050996)3.56720297
78serine family amino acid biosynthetic process (GO:0009070)3.56328680
79glucuronate metabolic process (GO:0019585)3.55467579
80uronic acid metabolic process (GO:0006063)3.55467579
81plasma lipoprotein particle assembly (GO:0034377)3.53290862
82cellular amino acid catabolic process (GO:0009063)3.53047891
83planar cell polarity pathway involved in neural tube closure (GO:0090179)3.52679670
84benzene-containing compound metabolic process (GO:0042537)3.52022206
85regulation of complement activation (GO:0030449)3.50845938
86dicarboxylic acid biosynthetic process (GO:0043650)3.47079374
87phospholipid homeostasis (GO:0055091)3.45617473
88response to nitrosative stress (GO:0051409)3.42997239
89regulation of water loss via skin (GO:0033561)3.41673659
90ketone body metabolic process (GO:1902224)3.39908261
91exogenous drug catabolic process (GO:0042738)3.39483824
92branching involved in mammary gland duct morphogenesis (GO:0060444)3.39422266
93apical protein localization (GO:0045176)3.39361537
94aldehyde catabolic process (GO:0046185)3.35986966
95sterol homeostasis (GO:0055092)3.33861170
96tyrosine metabolic process (GO:0006570)3.33214749
97cholesterol efflux (GO:0033344)3.33080501
98acute-phase response (GO:0006953)3.32618671
99regulation of branching involved in prostate gland morphogenesis (GO:0060687)3.32238795
100dichotomous subdivision of an epithelial terminal unit (GO:0060600)3.30680791
101lipoprotein metabolic process (GO:0042157)3.30323799
102cholesterol homeostasis (GO:0042632)3.30147550
103epithelial cell-cell adhesion (GO:0090136)3.29261431
104arginine metabolic process (GO:0006525)3.27659904
105carnitine metabolic process (GO:0009437)3.26768310
106fibrinolysis (GO:0042730)3.24883906
107gap junction assembly (GO:0016264)3.20585444
108positive regulation of lipoprotein lipase activity (GO:0051006)3.19933282
109positive regulation of triglyceride lipase activity (GO:0061365)3.19933282
1102-oxoglutarate metabolic process (GO:0006103)3.19334125
111lateral sprouting from an epithelium (GO:0060601)3.18184896
112protein-lipid complex assembly (GO:0065005)3.17900624
113tight junction assembly (GO:0070830)3.16768676
114multicellular organismal water homeostasis (GO:0050891)3.16452968
115positive regulation of pseudopodium assembly (GO:0031274)3.16198403
116regulation of establishment of planar polarity involved in neural tube closure (GO:0090178)3.15860914
117renal filtration (GO:0097205)3.15240446
118imidazole-containing compound metabolic process (GO:0052803)3.14474335
119regulation of bile acid biosynthetic process (GO:0070857)3.14302135
120calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules (GO:0016338)3.13870226
121valine metabolic process (GO:0006573)3.13861402
122drug metabolic process (GO:0017144)3.11812117
123positive regulation of Cdc42 GTPase activity (GO:0043089)3.10630659
124establishment or maintenance of epithelial cell apical/basal polarity (GO:0045197)3.10621804
125acetyl-CoA metabolic process (GO:0006084)3.08846455
126short-chain fatty acid metabolic process (GO:0046459)3.07564659
127regulation of keratinocyte differentiation (GO:0045616)3.05542477
128organic acid catabolic process (GO:0016054)3.03779463
129regulation of vascular endothelial growth factor signaling pathway (GO:1900746)3.01424618
130glomerular filtration (GO:0003094)2.93072010
131asymmetric protein localization (GO:0008105)2.92775453
132Wnt signaling pathway, planar cell polarity pathway (GO:0060071)2.87101271
133midgut development (GO:0007494)2.86212020
134renal system process involved in regulation of blood volume (GO:0001977)2.84869613
135notochord development (GO:0030903)2.84293999
136limb bud formation (GO:0060174)2.83961779
137protein retention in ER lumen (GO:0006621)2.83777773
138regulation of branching involved in salivary gland morphogenesis (GO:0060693)2.83509339
139epithelial tube branching involved in lung morphogenesis (GO:0060441)2.82857350
140establishment or maintenance of apical/basal cell polarity (GO:0035088)2.82499397
141establishment or maintenance of bipolar cell polarity (GO:0061245)2.82499397
142maintenance of protein localization in endoplasmic reticulum (GO:0035437)2.82474134
143surfactant homeostasis (GO:0043129)2.82115781
144establishment of skin barrier (GO:0061436)2.80307024
145branching involved in salivary gland morphogenesis (GO:0060445)2.79060141
146endothelial cell chemotaxis (GO:0035767)2.78635213
147cochlea morphogenesis (GO:0090103)2.75969999
148positive regulation of epidermal cell differentiation (GO:0045606)2.75888034
149maintenance of gastrointestinal epithelium (GO:0030277)2.74645839
150cell-cell junction assembly (GO:0007043)2.71865611
151cell adhesion mediated by integrin (GO:0033627)2.69589331
152regulation of cellular response to vascular endothelial growth factor stimulus (GO:1902547)2.68502606
153sodium ion export (GO:0071436)2.68437313
154regulation of establishment of planar polarity (GO:0090175)2.67541089
155auditory receptor cell differentiation (GO:0042491)2.67498151
156cellular protein complex localization (GO:0034629)2.66516011
157oligosaccharide biosynthetic process (GO:0009312)2.65332968
158establishment of apical/basal cell polarity (GO:0035089)2.64561921
159negative regulation of epidermal growth factor-activated receptor activity (GO:0007175)2.62750074
160regulation of pseudopodium assembly (GO:0031272)2.61423321
161O-glycan processing (GO:0016266)2.60648101
162regulation of vitamin metabolic process (GO:0030656)2.60432078
163positive regulation of keratinocyte differentiation (GO:0045618)2.60172160
164angiotensin maturation (GO:0002003)2.59694894
165negative regulation of transcription by competitive promoter binding (GO:0010944)2.58800620
166negative regulation of chondrocyte differentiation (GO:0032331)2.55084072
167negative regulation of epidermis development (GO:0045683)2.52537537
168positive regulation of glycoprotein metabolic process (GO:1903020)2.52515606
169semaphorin-plexin signaling pathway (GO:0071526)2.52167872
170water homeostasis (GO:0030104)2.51790498
171ear development (GO:0043583)2.49262160
172polarized epithelial cell differentiation (GO:0030859)2.49130386
173vitamin transmembrane transport (GO:0035461)2.47098309
174trophectodermal cell differentiation (GO:0001829)2.46424448
175regulation of epidermal cell differentiation (GO:0045604)2.46214721
176chemical homeostasis within a tissue (GO:0048875)2.45788066
177negative regulation of epidermal cell differentiation (GO:0045605)2.44908148
178protein complex localization (GO:0031503)2.41137536
179regulation of guanylate cyclase activity (GO:0031282)2.39074202
180COPI coating of Golgi vesicle (GO:0048205)2.38345642
181Golgi transport vesicle coating (GO:0048200)2.38345642
182positive regulation of glycoprotein biosynthetic process (GO:0010560)2.36148135
183membrane protein ectodomain proteolysis (GO:0006509)2.35345356
184adhesion of symbiont to host cell (GO:0044650)2.34595653
185virion attachment to host cell (GO:0019062)2.34595653
186nucleotide-sugar biosynthetic process (GO:0009226)2.34559013
187branching involved in labyrinthine layer morphogenesis (GO:0060670)2.33446830
188amyloid precursor protein catabolic process (GO:0042987)2.33317466
189cytoskeletal anchoring at plasma membrane (GO:0007016)2.33122120
190ectodermal placode formation (GO:0060788)2.29449101
191regulation of systemic arterial blood pressure by renin-angiotensin (GO:0003081)2.28125268
192regulation of epidermis development (GO:0045682)2.27735447
193cellular response to epidermal growth factor stimulus (GO:0071364)2.27601460
194ephrin receptor signaling pathway (GO:0048013)2.27383205
195non-canonical Wnt signaling pathway (GO:0035567)2.26318703
196chronic inflammatory response (GO:0002544)2.25941750
197hippo signaling (GO:0035329)2.25549366
198lens morphogenesis in camera-type eye (GO:0002089)2.24776838

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1ESR1_17901129_ChIP-ChIP_LIVER_Mouse8.90571703
2RXR_22158963_ChIP-Seq_LIVER_Mouse6.56040050
3PPARA_22158963_ChIP-Seq_LIVER_Mouse5.94409870
4LXR_22158963_ChIP-Seq_LIVER_Mouse5.21779138
5EGR1_23403033_ChIP-Seq_LIVER_Mouse4.50118334
6PPARG_19300518_ChIP-PET_3T3-L1_Mouse4.16732898
7FOXO1_23066095_ChIP-Seq_LIVER_Mouse4.12079001
8CEBPA_23403033_ChIP-Seq_LIVER_Mouse3.44862136
9TP63_17297297_ChIP-ChIP_HaCaT_Human3.24606544
10STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse3.09927308
11NR1I2_20693526_ChIP-Seq_LIVER_Mouse3.03737316
12CEBPB_23403033_ChIP-Seq_LIVER_Mouse2.52621405
13NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.45304808
14TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat2.37354701
15HNF4A_19761587_ChIP-ChIP_CACO-2_Human2.34666486
16TFAP2C_20629094_ChIP-Seq_MCF-7_Human2.21500135
17TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse2.19357629
18ZNF217_24962896_ChIP-Seq_MCF-7_Human2.17113150
19IRF8_22096565_ChIP-ChIP_GC-B_Human2.12106860
20SOX2_27498859_Chip-Seq_STOMACH_Mouse2.04042362
21STAT6_21828071_ChIP-Seq_BEAS2B_Human2.01803693
22CLOCK_20551151_ChIP-Seq_293T_Human1.99350253
23STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.97104435
24CDX2_20551321_ChIP-Seq_CACO-2_Human1.96751102
25TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.88708499
26RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.88370497
27BP1_19119308_ChIP-ChIP_Hs578T_Human1.81907758
28TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.67842096
29WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.67327584
30TCF7L2_21901280_ChIP-Seq_H4IIE_Rat1.67066809
31ZNF263_19887448_ChIP-Seq_K562_Human1.66400931
32Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.65644827
33GATA4_25053715_ChIP-Seq_YYC3_Human1.65408550
34KLF5_25053715_ChIP-Seq_YYC3_Human1.61615958
35EGR1_19374776_ChIP-ChIP_THP-1_Human1.58114476
36IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.55913356
37ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.55875988
38RBPJ_22232070_ChIP-Seq_NCS_Mouse1.55591821
39GATA6_25053715_ChIP-Seq_YYC3_Human1.49236711
40PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.47865151
41TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.47290080
42SOX2_18358816_ChIP-ChIP_MESCs_Mouse1.42094508
43SOX9_24532713_ChIP-Seq_HFSC_Mouse1.42030636
44ESR1_21235772_ChIP-Seq_MCF-7_Human1.41662469
45NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.40680957
46EOMES_20176728_ChIP-ChIP_TSCs_Mouse1.39274286
47MYB_21317192_ChIP-Seq_ERMYB_Mouse1.37034480
48ESR2_21235772_ChIP-Seq_MCF-7_Human1.36266639
49AHR_22903824_ChIP-Seq_MCF-7_Human1.35592983
50SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse1.33241222
51FOXA2_19822575_ChIP-Seq_HepG2_Human1.32044769
52NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.29280374
53FOXO3_23340844_ChIP-Seq_DLD1_Human1.28918185
54HNF4A_19822575_ChIP-Seq_HepG2_Human1.28691768
55STAT3_1855785_ChIP-Seq_MESCs_Mouse1.26779327
56SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.25521125
57UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.25308417
58BRD4_27068464_Chip-Seq_AML-cells_Mouse1.23773690
59KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.23359659
60CHD1_26751641_Chip-Seq_LNCaP_Human1.21809928
61ZFP281_18757296_ChIP-ChIP_E14_Mouse1.21637640
62IRF8_21731497_ChIP-ChIP_J774_Mouse1.21566511
63IRF8_27001747_Chip-Seq_BMDM_Mouse1.20430455
64UBF1/2_26484160_Chip-Seq_HMECs_Human1.19356969
65P63_26484246_Chip-Seq_KERATINOCYTES_Human1.18060217
66SALL4_18804426_ChIP-ChIP_XEN_Mouse1.15196049
67KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.14468660
68ERG_21242973_ChIP-ChIP_JURKAT_Human1.13840293
69KDM2B_26808549_Chip-Seq_K562_Human1.13439937
70TCF4_18268006_ChIP-ChIP_LS174T_Human1.13155226
71KLF4_18555785_ChIP-Seq_MESCs_Mouse1.12922398
72KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.10536681
73RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.10061201
74RARG_19884340_ChIP-ChIP_MEFs_Mouse1.10047301
75CREB1_26743006_Chip-Seq_LNCaP-abl_Human1.09442206
76SOX2_20726797_ChIP-Seq_SW620_Human1.08975975
77FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human1.08679399
78RACK7_27058665_Chip-Seq_MCF-7_Human1.07139095
79AR_21909140_ChIP-Seq_LNCAP_Human1.05894657
80SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.04897564
81NACC1_18358816_ChIP-ChIP_MESCs_Mouse1.04860455
82PPAR_26484153_Chip-Seq_NCI-H1993_Human1.04442884
83ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human1.03996644
84CREB1_26743006_Chip-Seq_LNCaP_Human1.03471898
85FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human1.02759448
86GATA1_26923725_Chip-Seq_HPCs_Mouse1.02543452
87TCF3_18692474_ChIP-Seq_MEFs_Mouse1.02028064
88NANOG_18692474_ChIP-Seq_MEFs_Mouse1.00657342
89ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse0.99414517
90CTNNB1_20460455_ChIP-Seq_HCT116_Human0.99154999
91EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse0.97520125
92ATF3_27146783_Chip-Seq_COLON_Human0.97271150
93OCT4_18692474_ChIP-Seq_MEFs_Mouse0.96953255
94NR0B1_18358816_ChIP-ChIP_MESCs_Mouse0.96663283
95TCF3_18692474_ChIP-Seq_MESCs_Mouse0.96618394
96RING1B_27294783_Chip-Seq_NPCs_Mouse0.96538089
97CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse0.96297868
98ARNT_22903824_ChIP-Seq_MCF-7_Human0.92042716
99ZFP281_27345836_Chip-Seq_ESCs_Mouse0.91770324
100PRDM14_21183938_ChIP-Seq_MESCs_Mouse0.91123197
101CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.90502001
102CJUN_26792858_Chip-Seq_BT549_Human0.90307636
103FOXM1_26456572_ChIP-Seq_MCF-7_Human0.89947841
104NANOG_18347094_ChIP-ChIP_MESCs_Mouse0.89788413
105HIF1A_21447827_ChIP-Seq_MCF-7_Human0.89150872
106SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse0.87048672
107CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human0.86609701
108PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.84848911
109STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse0.84711154
110FOXM1_23109430_ChIP-Seq_U2OS_Human0.84595743
111TP53_20018659_ChIP-ChIP_R1E_Mouse0.83942690
112FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human0.83332840
113AR_21915096_ChIP-Seq_LNCaP-1F5_Human0.83028606
114TCF7_22412390_ChIP-Seq_EML_Mouse0.82438595
115FOXA1_26743006_Chip-Seq_LNCaP-abl_Human0.80503402
116LXR_22292898_ChIP-Seq_THP-1_Human0.78952525
117TRIM28_21343339_ChIP-Seq_HEK293_Human0.77351683
118MYC_22102868_ChIP-Seq_BL_Human0.76768858
119ESR1_20079471_ChIP-ChIP_T-47D_Human0.74991215
120EGR1_19032775_ChIP-ChIP_M12_Human0.74321142
121PU_27001747_Chip-Seq_BMDM_Mouse0.73933413
122THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse0.73911453
123ESR1_15608294_ChIP-ChIP_MCF-7_Human0.73873070
124KLF5_18264089_ChIP-ChIP_MESCs_Mouse0.73556396
125KLF4_18264089_ChIP-ChIP_MESCs_Mouse0.73556396
126KLF2_18264089_ChIP-ChIP_MESCs_Mouse0.73556396
127RXRA_24833708_ChIP-Seq_LIVER_Mouse0.73215447
128P300_27058665_Chip-Seq_ZR-75-30cells_Human0.72348211
129GATA3_24758297_ChIP-Seq_MCF-7_Human0.72126682
130SMAD4_19686287_ChIP-ChIP_HaCaT_Human0.71670243
131NANOG_18700969_ChIP-ChIP_MESCs_Mouse0.71445233
132POU5F1_18700969_ChIP-ChIP_MESCs_Mouse0.71095889
133RUNX1_27514584_Chip-Seq_MCF-7_Human0.69764930
134ELK3_25401928_ChIP-Seq_HUVEC_Human0.68534369
135ZIC3_20872845_ChIP-ChIP_MESCs_Mouse0.67451988
136GATA1_22025678_ChIP-Seq_K562_Human0.65661296
137KDM2B_26808549_Chip-Seq_HPB-ALL_Human0.64611842
138SOX2_18692474_ChIP-Seq_MEFs_Mouse0.64038458
139GATA2_19941826_ChIP-Seq_K562_Human0.63793796
140TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse0.63720063
141SMAD3_18955504_ChIP-ChIP_HaCaT_Human0.63531193
142SMAD2_18955504_ChIP-ChIP_HaCaT_Human0.63531193
143FOXA1_25552417_ChIP-Seq_VCAP_Human0.63145930
144GATA2_22383799_ChIP-Seq_G1ME_Mouse0.62519994
145EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse0.62327207
146MAF_26560356_Chip-Seq_TH1_Human0.62160522
147ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human0.60860675
148TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.60841176

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0005360_urolithiasis6.86673889
2MP0002139_abnormal_hepatobiliary_system6.78231278
3MP0005085_abnormal_gallbladder_physiolo4.94250814
4MP0005365_abnormal_bile_salt4.58508190
5MP0000566_synostosis3.92186376
6MP0008875_abnormal_xenobiotic_pharmacok3.76997486
7MP0000537_abnormal_urethra_morphology3.20355896
8MP0003252_abnormal_bile_duct3.19895986
9MP0003806_abnormal_nucleotide_metabolis3.09650545
10MP0003195_calcinosis2.66117791
11MP0001666_abnormal_nutrient_absorption2.65503831
12MP0010329_abnormal_lipoprotein_level2.53508122
13MP0003941_abnormal_skin_development2.47367642
14MP0010678_abnormal_skin_adnexa2.35439636
15MP0005332_abnormal_amino_acid2.33847702
16MP0004019_abnormal_vitamin_homeostasis2.32869591
17MP0009840_abnormal_foam_cell2.31285643
18MP0000762_abnormal_tongue_morphology2.24097198
19MP0002138_abnormal_hepatobiliary_system2.23559420
20MP0005257_abnormal_intraocular_pressure2.21883620
21MP0003191_abnormal_cellular_cholesterol2.16525515
22MP0010030_abnormal_orbit_morphology2.04961908
23MP0005083_abnormal_biliary_tract1.97690432
24MP0010234_abnormal_vibrissa_follicle1.97394886
25MP0000462_abnormal_digestive_system1.97372891
26MP0003303_peritoneal_inflammation1.91425535
27MP0003705_abnormal_hypodermis_morpholog1.90349937
28MP0000467_abnormal_esophagus_morphology1.87304790
29MP0010352_gastrointestinal_tract_polyps1.85057414
30MP0000609_abnormal_liver_physiology1.84602086
31MP0000383_abnormal_hair_follicle1.83616726
32MP0004858_abnormal_nervous_system1.82531680
33MP0005409_darkened_coat_color1.77830082
34MP0002254_reproductive_system_inflammat1.63801136
35MP0003300_gastrointestinal_ulcer1.62450471
36MP0005319_abnormal_enzyme/_coenzyme1.56990464
37MP0002249_abnormal_larynx_morphology1.55663996
38MP0009643_abnormal_urine_homeostasis1.55519311
39MP0002118_abnormal_lipid_homeostasis1.54399436
40MP0001346_abnormal_lacrimal_gland1.54117512
41MP0009780_abnormal_chondrocyte_physiolo1.52163862
42MP0003315_abnormal_perineum_morphology1.50191041
43MP0004264_abnormal_extraembryonic_tissu1.45943319
44MP0003436_decreased_susceptibility_to1.40554822
45MP0002060_abnormal_skin_morphology1.40448548
46MP0003868_abnormal_feces_composition1.39897881
47MP0005451_abnormal_body_composition1.36329069
48MP0001188_hyperpigmentation1.36315861
49MP0010771_integument_phenotype1.35061224
50MP0004272_abnormal_basement_membrane1.33435662
51MP0001664_abnormal_digestion1.32813753
52MP0003186_abnormal_redox_activity1.29805820
53MP0002234_abnormal_pharynx_morphology1.27843196
54MP0005248_abnormal_Harderian_gland1.26997216
55MP0000534_abnormal_ureter_morphology1.23792486
56MP0003755_abnormal_palate_morphology1.21350889
57MP0002896_abnormal_bone_mineralization1.21333606
58MP0004957_abnormal_blastocyst_morpholog1.17700623
59MP0003693_abnormal_embryo_hatching1.16608248
60MP0002697_abnormal_eye_size1.15104605
61MP0001764_abnormal_homeostasis1.14902405
62MP0000049_abnormal_middle_ear1.13609264
63MP0009764_decreased_sensitivity_to1.13437725
64MP0005584_abnormal_enzyme/coenzyme_acti1.12506886
65MP0004185_abnormal_adipocyte_glucose1.11177045
66MP0002796_impaired_skin_barrier1.11171211
67MP0000598_abnormal_liver_morphology1.10037024
68MP0005636_abnormal_mineral_homeostasis1.08743474
69MP0005076_abnormal_cell_differentiation1.04685673
70MP0002089_abnormal_postnatal_growth/wei1.04343798
71MP0004947_skin_inflammation1.01667269
72MP0009379_abnormal_foot_pigmentation1.01185053
73MP0009278_abnormal_bone_marrow1.00487711
74MP0005167_abnormal_blood-brain_barrier0.99631738
75MP0005408_hypopigmentation0.99611392
76MP0008469_abnormal_protein_level0.99454773
77MP0003938_abnormal_ear_development0.99144218
78MP0000778_abnormal_nervous_system0.98807947
79MP0002136_abnormal_kidney_physiology0.98698257
80MP0004270_analgesia0.98275896
81MP0005623_abnormal_meninges_morphology0.98062940
82MP0005275_abnormal_skin_tensile0.97939269
83MP0004782_abnormal_surfactant_physiolog0.97157130
84MP0004043_abnormal_pH_regulation0.96604504
85MP0003937_abnormal_limbs/digits/tail_de0.95672798
86MP0005023_abnormal_wound_healing0.95571259
87MP0010155_abnormal_intestine_physiology0.95379713
88MP0002233_abnormal_nose_morphology0.94574643
89MP0000428_abnormal_craniofacial_morphol0.94221987
90MP0003091_abnormal_cell_migration0.94114755
91MP0002098_abnormal_vibrissa_morphology0.92159980
92MP0000432_abnormal_head_morphology0.91845998
93MP0001849_ear_inflammation0.90108177
94MP0005381_digestive/alimentary_phenotyp0.88168203
95MP0003453_abnormal_keratinocyte_physiol0.87267440
96MP0009053_abnormal_anal_canal0.87163799
97MP0005187_abnormal_penis_morphology0.85749301
98MP0001845_abnormal_inflammatory_respons0.84803019
99MP0002111_abnormal_tail_morphology0.83758416
100MP0009697_abnormal_copulation0.83532737
101MP0009763_increased_sensitivity_to0.82891620
102MP0003115_abnormal_respiratory_system0.81291152
103MP0001756_abnormal_urination0.81137132
104MP0000613_abnormal_salivary_gland0.81126894
105MP0003136_yellow_coat_color0.81015342
106MP0003283_abnormal_digestive_organ0.79302126
107MP0006082_CNS_inflammation0.79243058
108MP0004885_abnormal_endolymph0.78235995
109MP0009642_abnormal_blood_homeostasis0.78165855
110MP0005220_abnormal_exocrine_pancreas0.78031149
111MP0005464_abnormal_platelet_physiology0.77725345
112MP0003724_increased_susceptibility_to0.77158120
113MP0003935_abnormal_craniofacial_develop0.77071099
114MP0009785_altered_susceptibility_to0.76245918
115MP0001881_abnormal_mammary_gland0.76055038
116MP0000647_abnormal_sebaceous_gland0.75963028
117MP0002092_abnormal_eye_morphology0.75652720
118MP0009250_abnormal_appendicular_skeleto0.74501822
119MP0003942_abnormal_urinary_system0.74315680
120MP0005666_abnormal_adipose_tissue0.73641917
121MP0002282_abnormal_trachea_morphology0.73379559
122MP0009672_abnormal_birth_weight0.73356452
123MP0001243_abnormal_dermal_layer0.72350685
124MP0005503_abnormal_tendon_morphology0.72003666
125MP0008932_abnormal_embryonic_tissue0.71823004
126MP0000427_abnormal_hair_cycle0.71575813
127MP0002085_abnormal_embryonic_tissue0.71507974
128MP0002116_abnormal_craniofacial_bone0.71459342
129MP0002877_abnormal_melanocyte_morpholog0.71417634
130MP0000579_abnormal_nail_morphology0.70057144
131MP0005508_abnormal_skeleton_morphology0.69973246
132MP0005025_abnormal_response_to0.69610824
133MP0001216_abnormal_epidermal_layer0.69229590
134MP0005197_abnormal_uvea_morphology0.68825647
135MP0005166_decreased_susceptibility_to0.68742130
136MP0005647_abnormal_sex_gland0.68214846
137MP0000470_abnormal_stomach_morphology0.67565725
138MP0005084_abnormal_gallbladder_morpholo0.67549465
139MP0009384_cardiac_valve_regurgitation0.66771824
140MP0001286_abnormal_eye_development0.66357763
141MP0000678_abnormal_parathyroid_gland0.66244336
142MP0002419_abnormal_innate_immunity0.65977191
143MP0001765_abnormal_ion_homeostasis0.65460575
144MP0001542_abnormal_bone_strength0.64976170
145MP0001873_stomach_inflammation0.64064431
146MP0002078_abnormal_glucose_homeostasis0.64025889
147MP0000490_abnormal_crypts_of0.63934464
148MP0005058_abnormal_lysosome_morphology0.63736924
149MP0009765_abnormal_xenobiotic_induced0.60155791
150MP0004130_abnormal_muscle_cell0.59714124
151MP0001853_heart_inflammation0.59686292
152MP0000604_amyloidosis0.58604825
153MP0000377_abnormal_hair_follicle0.57712680
154MP0000477_abnormal_intestine_morphology0.57458430
155MP0000858_altered_metastatic_potential0.55960935
156MP0001545_abnormal_hematopoietic_system0.55118226
157MP0005397_hematopoietic_system_phenotyp0.55118226
158MP0003890_abnormal_embryonic-extraembry0.52859108
159MP0008873_increased_physiological_sensi0.52008315
160MP0001663_abnormal_digestive_system0.51641770
161MP0001533_abnormal_skeleton_physiology0.51479395
162MP0003075_altered_response_to0.50770287
163MP0005501_abnormal_skin_physiology0.50252433
164MP0010368_abnormal_lymphatic_system0.49454033
165MP0003566_abnormal_cell_adhesion0.49308368
166MP0005376_homeostasis/metabolism_phenot0.48742590
167MP0003221_abnormal_cardiomyocyte_apopto0.48209271
168MP0000627_abnormal_mammary_gland0.46879771
169MP0001915_intracranial_hemorrhage0.46158534
170MP0000538_abnormal_urinary_bladder0.46095117

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of monocarboxylic acid metabolism (HP:0010996)5.61557651
2Abnormality of aromatic amino acid family metabolism (HP:0004338)5.59904911
3Intrahepatic cholestasis (HP:0001406)5.59411475
4Deep venous thrombosis (HP:0002625)5.34838781
5Hypobetalipoproteinemia (HP:0003563)4.86487840
6Abnormality of glutamine family amino acid metabolism (HP:0010902)4.85025668
7Neonatal short-limb short stature (HP:0008921)4.65750011
8Xanthomatosis (HP:0000991)4.60428085
9Hypoglycemic coma (HP:0001325)4.50908370
10Prolonged partial thromboplastin time (HP:0003645)4.30261443
11Epidermoid cyst (HP:0200040)4.06049730
12Hyperammonemia (HP:0001987)3.93230730
13Joint hemorrhage (HP:0005261)3.74939758
14Complement deficiency (HP:0004431)3.67325445
15Ketosis (HP:0001946)3.63516391
16Abnormality of sulfur amino acid metabolism (HP:0004339)3.61385355
17Hyperglycinuria (HP:0003108)3.61076064
18Abnormality of the common coagulation pathway (HP:0010990)3.55826762
19Abnormality of the distal phalanx of the thumb (HP:0009617)3.47367931
20Gout (HP:0001997)3.46510070
21Fat malabsorption (HP:0002630)3.40371980
22Recurrent gram-negative bacterial infections (HP:0005420)3.38589848
23Hypolipoproteinemia (HP:0010981)3.34160321
24Abnormality of purine metabolism (HP:0004352)3.30242664
25Abnormality of nucleobase metabolism (HP:0010932)3.29962883
26Abnormality of pyrimidine metabolism (HP:0004353)3.29403321
27Abnormality of aspartate family amino acid metabolism (HP:0010899)3.28385782
28Hyperlipoproteinemia (HP:0010980)3.26318907
29Conjugated hyperbilirubinemia (HP:0002908)3.21467971
30Abnormality of glycine metabolism (HP:0010895)3.20837211
31Abnormality of serine family amino acid metabolism (HP:0010894)3.20837211
32Ketoacidosis (HP:0001993)3.12359964
33Hepatocellular carcinoma (HP:0001402)3.08710873
34Abnormality of the intrinsic pathway (HP:0010989)3.05910479
35Hypoglycemic seizures (HP:0002173)3.05622297
36Hyperglycinemia (HP:0002154)3.03898882
37Atrophic scars (HP:0001075)3.01830127
38Esophageal varix (HP:0002040)3.00963244
39Flat acetabular roof (HP:0003180)2.98105880
40Abnormality of the level of lipoprotein cholesterol (HP:0010979)2.96555306
41Abnormality of fatty-acid metabolism (HP:0004359)2.91623035
42Abnormality of complement system (HP:0005339)2.89860629
43Systemic lupus erythematosus (HP:0002725)2.89042757
44Myocardial infarction (HP:0001658)2.87145143
45Partial duplication of thumb phalanx (HP:0009944)2.83983914
46Hypercholesterolemia (HP:0003124)2.81266934
47Pili torti (HP:0003777)2.80108878
48Hyperparathyroidism (HP:0000843)2.77135066
49Hyperinsulinemic hypoglycemia (HP:0000825)2.76774646
50Symptomatic seizures (HP:0011145)2.75992993
51Generalized aminoaciduria (HP:0002909)2.73099195
52Aplasia involving bones of the upper limbs (HP:0009823)2.71581490
53Aplasia of the phalanges of the hand (HP:0009802)2.71581490
54Aplasia involving bones of the extremities (HP:0009825)2.71581490
55Vertebral hypoplasia (HP:0008417)2.70191570
56Aplasia/Hypoplasia of the vertebrae (HP:0008515)2.70191570
57Abnormality of proline metabolism (HP:0010907)2.68171533
58Hydroxyprolinuria (HP:0003080)2.68171533
59Proximal tubulopathy (HP:0000114)2.63084066
60Hypoalphalipoproteinemia (HP:0003233)2.59298105
61Malnutrition (HP:0004395)2.53864237
62Bronchomalacia (HP:0002780)2.52511547
63Spastic diplegia (HP:0001264)2.52249907
64Partial duplication of the phalanx of hand (HP:0009999)2.50947022
65Abnormality of methionine metabolism (HP:0010901)2.50514045
66Broad metatarsal (HP:0001783)2.49970209
67Alopecia of scalp (HP:0002293)2.49043839
68Pancreatitis (HP:0001733)2.48398936
69Milia (HP:0001056)2.47886665
70Nausea (HP:0002018)2.45309783
71Abnormality of nail color (HP:0100643)2.45042320
72Curly hair (HP:0002212)2.44033775
73Thrombophlebitis (HP:0004418)2.40505771
74Hyperactive renin-angiotensin system (HP:0000841)2.38805590
75Abnormality of long-chain fatty-acid metabolism (HP:0010964)2.37010319
76Arterial tortuosity (HP:0005116)2.34419481
77Metabolic acidosis (HP:0001942)2.33988486
78Vascular calcification (HP:0004934)2.32043377
79Vascular tortuosity (HP:0004948)2.31897850
80Hemorrhage of the eye (HP:0011885)2.31780539
81Hypochromic microcytic anemia (HP:0004840)2.31618463
82Eczematoid dermatitis (HP:0000976)2.30468137
83Hyperuricemia (HP:0002149)2.29694232
84Increased purine levels (HP:0004368)2.29694232
85Hyperbilirubinemia (HP:0002904)2.28884567
86Abnormality of renin-angiotensin system (HP:0000847)2.28678367
87Spinal cord compression (HP:0002176)2.27722803
88Delayed CNS myelination (HP:0002188)2.27592184
89Steatorrhea (HP:0002570)2.27452084
90Alkalosis (HP:0001948)2.26053177
91Taurodontia (HP:0000679)2.25364627
92Abnormality of permanent molar morphology (HP:0011071)2.25364627
93Abnormality of the dental root (HP:0006486)2.25364627
94Late onset (HP:0003584)2.20305354
95Coronal craniosynostosis (HP:0004440)2.16212283
96Pterygium (HP:0001059)2.15074353
97Abnormal cartilage morphology (HP:0002763)2.13715237
98Chronic bronchitis (HP:0004469)2.13488643
99Renal tubular acidosis (HP:0001947)2.12094119
100Abnormal enzyme/coenzyme activity (HP:0012379)2.11810846
101Glycosuria (HP:0003076)2.09856642
102Abnormality of urine glucose concentration (HP:0011016)2.09856642
103Abnormality of molar (HP:0011077)2.09777729
104Abnormality of molar morphology (HP:0011070)2.09777729
105Right ventricular cardiomyopathy (HP:0011663)2.09721006
106Abnormality of the salivary glands (HP:0010286)2.09366843
107Abnormal ossification of hand bones (HP:0005921)2.09081795
108Down-sloping shoulders (HP:0200021)2.08994652
109Tibial bowing (HP:0002982)2.08451037
110Abnormality of the phalanges of the hallux (HP:0010057)2.06695042
111Spontaneous abortion (HP:0005268)2.06568595
112Fragile skin (HP:0001030)2.05828518
113Dicarboxylic aciduria (HP:0003215)2.05794195
114Abnormality of dicarboxylic acid metabolism (HP:0010995)2.05794195
115Thick nail (HP:0001805)2.05596267
116Hepatoblastoma (HP:0002884)2.05473743
117Irritability (HP:0000737)2.05296630
118Protrusio acetabuli (HP:0003179)2.04856854
119Fragile nails (HP:0001808)2.04587344
120Menorrhagia (HP:0000132)2.03953328
121Abnormality of the gastric mucosa (HP:0004295)2.03304773
122Rickets (HP:0002748)2.03032048
123Glomerulonephritis (HP:0000099)2.02213903
124Aplasia/Hypoplasia of the phalanges of the thumb (HP:0009658)2.01869249
125Abnormal hair laboratory examination (HP:0003328)2.01772774
126Abnormality of carpal bone ossification (HP:0006257)2.01574551
127Abnormality of serum amino acid levels (HP:0003112)2.01311447
128Recurrent bacterial skin infections (HP:0005406)2.00721533
129Vertebral arch anomaly (HP:0008438)2.00227310
130Gingival bleeding (HP:0000225)1.97895775
131Hypoplasia of dental enamel (HP:0006297)1.96761352
132Gastrointestinal infarctions (HP:0005244)1.96659033
133Cardiovascular calcification (HP:0011915)1.96585302
134Abnormality of the dental pulp (HP:0006479)1.96272354
135Absent eyelashes (HP:0000561)1.96231900
136Abdominal distention (HP:0003270)1.94842561
137Nephritis (HP:0000123)1.93778746
138Abnormality of alkaline phosphatase activity (HP:0004379)1.93499211
139Premature rupture of membranes (HP:0001788)1.92874629
140Skin nodule (HP:0200036)1.92303582
141Natal tooth (HP:0000695)1.91949298
142Bifid scrotum (HP:0000048)1.91875932
143Broad face (HP:0000283)1.91814206
144Acute hepatic failure (HP:0006554)1.91492151
145Amyloidosis (HP:0011034)1.91336500
146Hyperaldosteronism (HP:0000859)1.90708681
147Abnormality of the distal phalanges of the toes (HP:0010182)1.90513671
148Hypophosphatemia (HP:0002148)1.90342592
149Abnormality of chloride homeostasis (HP:0011422)1.89862663
150Plantar hyperkeratosis (HP:0007556)1.89008674
151Hereditary nonpolyposis colorectal carcinoma (HP:0006716)1.88407922
152Abnormal hand bone ossification (HP:0010660)1.88340483
153Thin bony cortex (HP:0002753)1.88122075
154Nephrolithiasis (HP:0000787)1.87279606
155Esophageal atresia (HP:0002032)1.87068513
156Lip pit (HP:0100267)1.86835605
157Onycholysis (HP:0001806)1.86702652
158Missing ribs (HP:0000921)1.86603844
159Pulmonary embolism (HP:0002204)1.86342466
160Lethargy (HP:0001254)1.85944422
161Decreased circulating renin level (HP:0003351)1.85900889
162Short nail (HP:0001799)1.85427943
163Abnormal vertebral ossification (HP:0100569)1.85335804
164Sparse lateral eyebrow (HP:0005338)1.85307621
165Metabolic alkalosis (HP:0200114)1.85260609
166Abnormal tarsal ossification (HP:0008369)1.84863771
167Abnormality of transition element cation homeostasis (HP:0011030)1.83902821
168Sensorimotor neuropathy (HP:0007141)1.83759591
169Subacute progressive viral hepatitis (HP:0006572)1.83482212
170Morphological abnormality of the middle ear (HP:0008609)1.82424225
171Vomiting (HP:0002013)1.81788161
172Shallow orbits (HP:0000586)1.80870042
173Selective tooth agenesis (HP:0001592)1.79519057
174Turricephaly (HP:0000262)1.79349919
175Focal segmental glomerulosclerosis (HP:0000097)1.76277506
176Thickened helices (HP:0000391)1.75427053
177Ulnar bowing (HP:0003031)1.74075993
178Genu recurvatum (HP:0002816)1.70908011
179Septate vagina (HP:0001153)1.70042522
180Multiple lipomas (HP:0001012)1.67829961
181Megalencephaly (HP:0001355)1.64910208
182Hyperacusis (HP:0010780)1.63483505
183Flattened epiphyses (HP:0003071)1.63100947
184Abnormal umbilical cord blood vessels (HP:0011403)1.62486377
185Single umbilical artery (HP:0001195)1.62486377
186Abnormality of the fetal cardiovascular system (HP:0010948)1.62486377
187Congenital ichthyosiform erythroderma (HP:0007431)1.60696747
188Breech presentation (HP:0001623)1.59548297
189Osteolytic defects of the hand bones (HP:0009699)1.59282976
190Osteolytic defects of the phalanges of the hand (HP:0009771)1.59282976

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BCKDK3.79527868
2MAP3K103.66575710
3ERN13.56209945
4TRIB33.14889939
5PKN22.98169948
6PNCK2.57745658
7MST1R2.49816451
8ERBB42.46615067
9LATS12.45491156
10STK242.31674515
11IRAK32.27953273
12TNIK2.22698525
13FRK2.20272632
14FGFR42.12613587
15SMG12.09494122
16STK392.01411378
17NTRK12.00828048
18TAOK31.94263273
19CASK1.92769222
20SIK11.92617500
21PTK61.86020838
22LMTK21.82695966
23WEE11.82292331
24MAP3K141.74444221
25CDK61.74437473
26TBK11.62365110
27ABL21.60983036
28RPS6KA41.49774498
29STK101.42355721
30MAP3K31.34162809
31RIPK41.27888339
32NEK11.27166075
33GRK61.27054976
34TXK1.24079484
35MAP3K91.23111952
36EPHA21.22323901
37BMX1.20300266
38INSRR1.19187697
39TYK21.18873631
40JAK21.17007512
41ICK1.14734545
42MAP4K11.14339456
43STK38L1.14028445
44MAP2K21.12635695
45PIK3CA1.10401424
46EPHB21.10350644
47CDK121.09563960
48CSK1.09122219
49EEF2K1.09082855
50MAPK111.08803609
51LRRK21.08047694
52TAF11.06590171
53MAP3K111.05588926
54CHUK1.05102248
55PIM11.04355797
56PBK1.03830082
57DMPK1.02938842
58FLT31.02046639
59ERBB21.01749741
60MST41.01393987
61GSK3A1.01256467
62WNK41.01015765
63BUB11.00005354
64AKT30.99415752
65FGFR30.98215275
66STK30.97873701
67ARAF0.94813380
68BCR0.92526608
69NEK90.92044753
70KDR0.91868781
71PIM20.91566560
72TSSK60.89586921
73TTK0.89305719
74MAP3K120.88208308
75TESK10.87699981
76RPS6KB20.85830137
77MAP3K50.84591597
78MARK30.83686632
79CDK40.82870695
80JAK30.82118192
81VRK20.81669295
82MAP3K20.81468693
83NME20.78860477
84MATK0.78160573
85PRKD30.77443151
86OXSR10.75392290
87YES10.74260567
88MAP2K30.73533871
89MKNK20.73522602
90IKBKB0.71947629
91ZAP700.71842726
92MAP3K60.71234050
93FGFR10.69714779
94RIPK10.67448330
95TGFBR20.67361762
96PTK20.66982389
97MAP3K80.66911790
98DYRK1B0.65488641
99IRAK40.65199054
100MET0.64794165
101EGFR0.64466512
102PRKCZ0.63494121
103LATS20.62868334
104WNK30.62393354
105MAPK40.62071161
106MOS0.59878467
107KSR20.59736775
108PDGFRA0.58977709
109MARK10.58335698
110BRAF0.57483756
111TRIM280.56484241
112BRSK20.56313921
113RPS6KA10.55638237
114MKNK10.55403925
115MTOR0.55090271
116ROCK20.54870972
117BMPR20.54832857
118TYRO30.54493386
119JAK10.53965613
120CDK70.51888520
121ACVR1B0.51686348
122ABL10.51336811
123PRKAA10.51314161
124LIMK10.50514081
125CAMK2D0.50072916
126BLK0.49990217
127TAOK10.49361335
128DYRK30.48928925
129MAP3K70.46829238
130IKBKE0.46569203
131MAPK150.46310009
132KSR10.45854857
133DDR20.45675547
134NEK60.45542894
135ILK0.45402634
136FER0.45036758
137SCYL20.44491622
138MELK0.43639794
139PRKACG0.43515123
140EPHA30.41851547
141PRKG20.41849665
142EPHB10.41822260
143PRKAA20.41337741
144NEK20.40968205
145PDGFRB0.40285803
146PAK40.39855513
147CAMK1G0.39047569
148MAP2K40.38510630
149CAMK2B0.38357658
150MAP2K10.37947022
151RPS6KA20.37647126
152PAK20.36969073
153CAMK2G0.36964898
154CDK90.35725123
155PRKCI0.35711563
156MAPKAPK50.35654403
157CDK180.34923031
158MAP3K10.34813615
159NME10.32770726

Predicted pathways (KEGG)

RankGene SetZ-score
1Nitrogen metabolism_Homo sapiens_hsa009104.14269875
2Ascorbate and aldarate metabolism_Homo sapiens_hsa000533.67145073
3Primary bile acid biosynthesis_Homo sapiens_hsa001203.58951001
4Arginine biosynthesis_Homo sapiens_hsa002202.95202967
5Pentose and glucuronate interconversions_Homo sapiens_hsa000402.63861317
6Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004002.63087731
7Tryptophan metabolism_Homo sapiens_hsa003802.62648462
8Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006302.47835179
9Fatty acid degradation_Homo sapiens_hsa000712.33076841
10Complement and coagulation cascades_Homo sapiens_hsa046102.28603128
11Selenocompound metabolism_Homo sapiens_hsa004502.22762393
12Valine, leucine and isoleucine degradation_Homo sapiens_hsa002802.15416617
13Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005122.13383112
14Glycine, serine and threonine metabolism_Homo sapiens_hsa002602.07513874
15Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006012.02491278
16Staphylococcus aureus infection_Homo sapiens_hsa051501.98363541
17Tight junction_Homo sapiens_hsa045301.96633501
18Peroxisome_Homo sapiens_hsa041461.94046762
19Sulfur metabolism_Homo sapiens_hsa009201.89615932
20Protein digestion and absorption_Homo sapiens_hsa049741.88313994
21Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.87304565
22Butanoate metabolism_Homo sapiens_hsa006501.86742799
23Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.81585973
24Drug metabolism - other enzymes_Homo sapiens_hsa009831.80961757
25Histidine metabolism_Homo sapiens_hsa003401.74429106
26Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.73552743
27Caffeine metabolism_Homo sapiens_hsa002321.71184493
28Chemical carcinogenesis_Homo sapiens_hsa052041.71180072
29beta-Alanine metabolism_Homo sapiens_hsa004101.70528947
30PPAR signaling pathway_Homo sapiens_hsa033201.68524845
31Maturity onset diabetes of the young_Homo sapiens_hsa049501.65136292
32Fat digestion and absorption_Homo sapiens_hsa049751.63337594
332-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.61811873
34Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.52751649
35Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.51726321
36Bile secretion_Homo sapiens_hsa049761.51699051
37Fatty acid metabolism_Homo sapiens_hsa012121.49650323
38Thyroid cancer_Homo sapiens_hsa052161.48617413
39Hippo signaling pathway_Homo sapiens_hsa043901.47112341
40Steroid hormone biosynthesis_Homo sapiens_hsa001401.47076683
41Propanoate metabolism_Homo sapiens_hsa006401.46072024
42Retinol metabolism_Homo sapiens_hsa008301.45297290
43Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.40986575
44Basal cell carcinoma_Homo sapiens_hsa052171.40803877
45Folate biosynthesis_Homo sapiens_hsa007901.40342242
46Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.38507351
47Vitamin digestion and absorption_Homo sapiens_hsa049771.36878372
48Starch and sucrose metabolism_Homo sapiens_hsa005001.36181179
49Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002501.36072749
50Bacterial invasion of epithelial cells_Homo sapiens_hsa051001.33117652
51Notch signaling pathway_Homo sapiens_hsa043301.32891200
52Central carbon metabolism in cancer_Homo sapiens_hsa052301.31957970
53Phenylalanine metabolism_Homo sapiens_hsa003601.19459192
54Cyanoamino acid metabolism_Homo sapiens_hsa004601.17826397
55Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.17187281
56Hedgehog signaling pathway_Homo sapiens_hsa043401.11052290
57Axon guidance_Homo sapiens_hsa043601.09420255
58Vitamin B6 metabolism_Homo sapiens_hsa007501.09403658
59Endometrial cancer_Homo sapiens_hsa052131.09368196
60Proteoglycans in cancer_Homo sapiens_hsa052051.09033892
61MicroRNAs in cancer_Homo sapiens_hsa052061.08664103
62Chronic myeloid leukemia_Homo sapiens_hsa052201.07137878
63Carbon metabolism_Homo sapiens_hsa012001.05147631
64Renal cell carcinoma_Homo sapiens_hsa052111.02759342
65ErbB signaling pathway_Homo sapiens_hsa040121.00558526
66Biosynthesis of amino acids_Homo sapiens_hsa012300.99934180
67Prostate cancer_Homo sapiens_hsa052150.99054919
68Pyruvate metabolism_Homo sapiens_hsa006200.97750727
69Sphingolipid metabolism_Homo sapiens_hsa006000.95570503
70Pancreatic secretion_Homo sapiens_hsa049720.94946837
71Cysteine and methionine metabolism_Homo sapiens_hsa002700.94832791
72Vibrio cholerae infection_Homo sapiens_hsa051100.94032571
73ABC transporters_Homo sapiens_hsa020100.93599050
74Glutathione metabolism_Homo sapiens_hsa004800.92755619
75Lysine degradation_Homo sapiens_hsa003100.92296613
76Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.91797808
77Arginine and proline metabolism_Homo sapiens_hsa003300.90344069
78Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.90035375
79Thyroid hormone synthesis_Homo sapiens_hsa049180.89829189
80Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.88898674
81TGF-beta signaling pathway_Homo sapiens_hsa043500.85535008
82Small cell lung cancer_Homo sapiens_hsa052220.84288060
83ECM-receptor interaction_Homo sapiens_hsa045120.83506481
84Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.82595918
85Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.81658825
86Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.81482384
87Estrogen signaling pathway_Homo sapiens_hsa049150.80561194
88Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.80099858
89One carbon pool by folate_Homo sapiens_hsa006700.79564401
90Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.78191658
91Tyrosine metabolism_Homo sapiens_hsa003500.77781378
92Legionellosis_Homo sapiens_hsa051340.77610703
93Steroid biosynthesis_Homo sapiens_hsa001000.75041103
94Pancreatic cancer_Homo sapiens_hsa052120.73443632
95AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.70912805
96Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.69721864
97Melanogenesis_Homo sapiens_hsa049160.69337136
98Focal adhesion_Homo sapiens_hsa045100.69267965
99Leishmaniasis_Homo sapiens_hsa051400.65262776
100Sulfur relay system_Homo sapiens_hsa041220.64962952
101Wnt signaling pathway_Homo sapiens_hsa043100.62355043
102Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.60150886
103Leukocyte transendothelial migration_Homo sapiens_hsa046700.59221963
104Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.58637950
105Pertussis_Homo sapiens_hsa051330.57839729
106Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.57817170
107Pathways in cancer_Homo sapiens_hsa052000.57051218
108Gap junction_Homo sapiens_hsa045400.55249703
109Pentose phosphate pathway_Homo sapiens_hsa000300.55113774
110Glycerolipid metabolism_Homo sapiens_hsa005610.54637804
111Galactose metabolism_Homo sapiens_hsa000520.54371023
112Melanoma_Homo sapiens_hsa052180.54152945
113Insulin resistance_Homo sapiens_hsa049310.50805315
114Colorectal cancer_Homo sapiens_hsa052100.50762907
115Thyroid hormone signaling pathway_Homo sapiens_hsa049190.46240444
116Prion diseases_Homo sapiens_hsa050200.45909894
117Cocaine addiction_Homo sapiens_hsa050300.45667464
118Glioma_Homo sapiens_hsa052140.43891239
119Fatty acid elongation_Homo sapiens_hsa000620.42155169
120Insulin signaling pathway_Homo sapiens_hsa049100.41314408
121Longevity regulating pathway - mammal_Homo sapiens_hsa042110.41186468
122Renin-angiotensin system_Homo sapiens_hsa046140.41158261
123Rap1 signaling pathway_Homo sapiens_hsa040150.40923882
124Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.40661608
125Fatty acid biosynthesis_Homo sapiens_hsa000610.39393915
126Choline metabolism in cancer_Homo sapiens_hsa052310.38478970
127NOD-like receptor signaling pathway_Homo sapiens_hsa046210.37177753
128Fructose and mannose metabolism_Homo sapiens_hsa000510.35586317
129TNF signaling pathway_Homo sapiens_hsa046680.34036633
130Adipocytokine signaling pathway_Homo sapiens_hsa049200.31117824
131Mineral absorption_Homo sapiens_hsa049780.30943030
132Toll-like receptor signaling pathway_Homo sapiens_hsa046200.28355511
133Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.27565174
134Tuberculosis_Homo sapiens_hsa051520.25622516
135Metabolic pathways_Homo sapiens_hsa011000.23462630
136alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.21584163
137Bladder cancer_Homo sapiens_hsa052190.21279977
138African trypanosomiasis_Homo sapiens_hsa051430.19850614
139NF-kappa B signaling pathway_Homo sapiens_hsa040640.18631320
140Hepatitis C_Homo sapiens_hsa051600.18376533
141Amoebiasis_Homo sapiens_hsa051460.18164150
142Adherens junction_Homo sapiens_hsa045200.16607042
143Osteoclast differentiation_Homo sapiens_hsa043800.16379028
144Carbohydrate digestion and absorption_Homo sapiens_hsa049730.15776203
145Influenza A_Homo sapiens_hsa051640.12821924
146RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.12323384
147Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.11193726
148Acute myeloid leukemia_Homo sapiens_hsa052210.11019631
149Toxoplasmosis_Homo sapiens_hsa051450.09101845
150Linoleic acid metabolism_Homo sapiens_hsa005910.06314577
151AMPK signaling pathway_Homo sapiens_hsa041520.05625270
152Prolactin signaling pathway_Homo sapiens_hsa049170.05244211
153Graft-versus-host disease_Homo sapiens_hsa053320.03113322
154Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.01811158

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »