ABHD18

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1behavioral response to nicotine (GO:0035095)5.19888400
2regulation of glucokinase activity (GO:0033131)4.30843855
3regulation of hexokinase activity (GO:1903299)4.30843855
4L-fucose catabolic process (GO:0042355)4.18956377
5fucose catabolic process (GO:0019317)4.18956377
6L-fucose metabolic process (GO:0042354)4.18956377
7presynaptic membrane assembly (GO:0097105)4.08538407
8DNA deamination (GO:0045006)3.86683089
9presynaptic membrane organization (GO:0097090)3.69314919
10response to pheromone (GO:0019236)3.46351025
11neural tube formation (GO:0001841)3.33484099
12neuron cell-cell adhesion (GO:0007158)3.31402478
13cellular ketone body metabolic process (GO:0046950)3.18948467
14replication fork processing (GO:0031297)3.16599882
15protein complex biogenesis (GO:0070271)3.16399344
16negative regulation of telomere maintenance (GO:0032205)3.15977353
17platelet dense granule organization (GO:0060155)3.12902377
18axoneme assembly (GO:0035082)3.04501011
19tryptophan catabolic process (GO:0006569)3.00277252
20indole-containing compound catabolic process (GO:0042436)3.00277252
21indolalkylamine catabolic process (GO:0046218)3.00277252
22inositol phosphate catabolic process (GO:0071545)3.00137595
23piRNA metabolic process (GO:0034587)2.99916575
24response to stimulus involved in regulation of muscle adaptation (GO:0014874)2.99829197
25ubiquinone biosynthetic process (GO:0006744)2.98209723
26kidney morphogenesis (GO:0060993)2.97436220
27adaptation of signaling pathway (GO:0023058)2.96444300
28mitochondrial respiratory chain complex assembly (GO:0033108)2.93858580
29aromatic amino acid family catabolic process (GO:0009074)2.93222437
30mitochondrial respiratory chain complex I assembly (GO:0032981)2.92882085
31NADH dehydrogenase complex assembly (GO:0010257)2.92882085
32mitochondrial respiratory chain complex I biogenesis (GO:0097031)2.92882085
33detection of calcium ion (GO:0005513)2.92733605
34negative regulation of synaptic transmission, GABAergic (GO:0032229)2.92212330
35epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)2.89803709
36cytochrome complex assembly (GO:0017004)2.88467773
37protein K11-linked deubiquitination (GO:0035871)2.87746910
38nucleotide transmembrane transport (GO:1901679)2.87391062
39polyol catabolic process (GO:0046174)2.86378608
40ketone body metabolic process (GO:1902224)2.85603297
41tryptophan metabolic process (GO:0006568)2.85547163
42positive regulation of action potential (GO:0045760)2.85516356
43regulation of meiosis I (GO:0060631)2.84960508
44erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222)2.84628852
45L-phenylalanine catabolic process (GO:0006559)2.84628852
46respiratory chain complex IV assembly (GO:0008535)2.84298011
47magnesium ion transport (GO:0015693)2.84192714
48male meiosis I (GO:0007141)2.84056270
49axon ensheathment in central nervous system (GO:0032291)2.81636340
50central nervous system myelination (GO:0022010)2.81636340
51mitochondrial electron transport, NADH to ubiquinone (GO:0006120)2.80692831
52water-soluble vitamin biosynthetic process (GO:0042364)2.80649616
53postsynaptic membrane organization (GO:0001941)2.80259312
54S-adenosylmethionine metabolic process (GO:0046500)2.79455841
55protein localization to cilium (GO:0061512)2.78742736
56ubiquinone metabolic process (GO:0006743)2.78554493
57protein-cofactor linkage (GO:0018065)2.77993875
58sulfation (GO:0051923)2.77680640
59synapsis (GO:0007129)2.75838491
60polyketide metabolic process (GO:0030638)2.75487552
61doxorubicin metabolic process (GO:0044598)2.75487552
62daunorubicin metabolic process (GO:0044597)2.75487552
63recombinational repair (GO:0000725)2.74114358
64phosphorylated carbohydrate dephosphorylation (GO:0046838)2.73201919
65inositol phosphate dephosphorylation (GO:0046855)2.73201919
66double-strand break repair via homologous recombination (GO:0000724)2.71096895
67fatty acid elongation (GO:0030497)2.71091419
68amine catabolic process (GO:0009310)2.70822467
69cellular biogenic amine catabolic process (GO:0042402)2.70822467
70glycerophospholipid catabolic process (GO:0046475)2.70319898
71rRNA catabolic process (GO:0016075)2.68915046
72interkinetic nuclear migration (GO:0022027)2.68571676
73DNA double-strand break processing (GO:0000729)2.68333682
74protein K6-linked ubiquitination (GO:0085020)2.68124974
75G-protein coupled glutamate receptor signaling pathway (GO:0007216)2.66873026
76RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503)2.65546104
77membrane depolarization during cardiac muscle cell action potential (GO:0086012)2.65212229
78centriole replication (GO:0007099)2.63462989
79startle response (GO:0001964)2.60955536
80regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)2.60885311
81epithelial cilium movement (GO:0003351)2.60603376
82righting reflex (GO:0060013)2.59793867
83reciprocal DNA recombination (GO:0035825)2.57883897
84reciprocal meiotic recombination (GO:0007131)2.57883897
85regulation of memory T cell differentiation (GO:0043380)2.53988739
86oxidative demethylation (GO:0070989)2.53756715
87tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)2.53661148
88RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)2.53661148
89glutamate receptor signaling pathway (GO:0007215)2.53503219
90neurotransmitter-gated ion channel clustering (GO:0072578)2.51947698
91ionotropic glutamate receptor signaling pathway (GO:0035235)2.51689173
92indolalkylamine metabolic process (GO:0006586)2.51006980
93negative regulation of cytosolic calcium ion concentration (GO:0051481)2.50975192
94response to epinephrine (GO:0071871)2.50697979
95negative regulation of DNA-dependent DNA replication (GO:2000104)2.50073709
96negative regulation of transcription regulatory region DNA binding (GO:2000678)2.50070107
97male meiosis (GO:0007140)2.48925431
98DNA demethylation (GO:0080111)2.48429890
99NAD biosynthetic process (GO:0009435)2.47587457
100regulation of rhodopsin mediated signaling pathway (GO:0022400)2.47496353
101protein prenylation (GO:0018342)2.45577924
102prenylation (GO:0097354)2.45577924
103negative regulation of mast cell activation (GO:0033004)2.45577020
104DNA methylation involved in gamete generation (GO:0043046)2.45545615
105synaptic transmission, cholinergic (GO:0007271)2.45331021
106quinone biosynthetic process (GO:1901663)2.45328841
107long-chain fatty acid biosynthetic process (GO:0042759)2.45119452
108cerebral cortex radially oriented cell migration (GO:0021799)2.44762044
109adrenergic receptor signaling pathway (GO:0071875)2.43760759
110superoxide anion generation (GO:0042554)2.42823973
111reflex (GO:0060004)2.42519187
112regulation of telomere maintenance (GO:0032204)2.41891719
113establishment of protein localization to mitochondrial membrane (GO:0090151)2.41881951
114rhodopsin mediated signaling pathway (GO:0016056)2.41326637
115somatic diversification of immune receptors via somatic mutation (GO:0002566)2.40363412
116somatic hypermutation of immunoglobulin genes (GO:0016446)2.40363412
117polyol transport (GO:0015791)2.40286991
118regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion (GO2.39312860
119regulation of cell communication by electrical coupling (GO:0010649)2.38320434
120negative regulation of neurotransmitter transport (GO:0051589)2.37477371
121regulation of sarcomere organization (GO:0060297)2.37289861
122detection of light stimulus involved in sensory perception (GO:0050962)2.36957149
123detection of light stimulus involved in visual perception (GO:0050908)2.36957149
124membrane assembly (GO:0071709)2.36260058
125regulation of relaxation of muscle (GO:1901077)2.34958232
126cytidine deamination (GO:0009972)2.34489109
127cytidine metabolic process (GO:0046087)2.34489109
128cytidine catabolic process (GO:0006216)2.34489109
129regulation of timing of cell differentiation (GO:0048505)2.34385488
130protein polyglutamylation (GO:0018095)2.34373031
131coenzyme catabolic process (GO:0009109)2.34372619
132somite rostral/caudal axis specification (GO:0032525)2.33404318
133cyclic nucleotide catabolic process (GO:0009214)2.32789611
134mannosylation (GO:0097502)2.32763090
135establishment of protein localization to Golgi (GO:0072600)2.32528088
136indole-containing compound metabolic process (GO:0042430)2.31411378
137response to redox state (GO:0051775)2.31320147
138spinal cord motor neuron differentiation (GO:0021522)2.31212544
139regulation of translation, ncRNA-mediated (GO:0045974)2.31197672
140regulation of cardiac muscle contraction by calcium ion signaling (GO:0010882)2.30058275
141kynurenine metabolic process (GO:0070189)2.28116170
142erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221)2.27438260
143L-phenylalanine metabolic process (GO:0006558)2.27438260
144regulation of bile acid biosynthetic process (GO:0070857)2.27186164
145regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum (GO:0010880)2.27131427
146tyrosine metabolic process (GO:0006570)2.26729228
147developmental pigmentation (GO:0048066)2.26599112
148gamma-aminobutyric acid signaling pathway (GO:0007214)2.26575431
149vocalization behavior (GO:0071625)2.25834154
150regulation of pigment cell differentiation (GO:0050932)2.25237613
151calcium ion import (GO:0070509)2.25222796
152cellular response to epinephrine stimulus (GO:0071872)2.23630941
153retina layer formation (GO:0010842)2.22587769
154regulation of actin filament-based movement (GO:1903115)2.21799809
155behavioral response to cocaine (GO:0048148)2.21316323
156protein localization to synapse (GO:0035418)2.21046725
157cAMP catabolic process (GO:0006198)2.20631814
158nonmotile primary cilium assembly (GO:0035058)2.20431676
159regulation of cardiac muscle cell contraction (GO:0086004)2.20076998
160androgen biosynthetic process (GO:0006702)2.19984818
161opioid receptor signaling pathway (GO:0038003)2.19206137
162photoreceptor cell maintenance (GO:0045494)2.19138698
163GPI anchor metabolic process (GO:0006505)2.19119380
164detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)2.18140949
165regulation of inhibitory postsynaptic membrane potential (GO:0060080)2.17557179
166nucleotide transport (GO:0006862)2.16992940
167positive regulation of heart rate (GO:0010460)2.15819717
168adenosine metabolic process (GO:0046085)2.14930651
169dopamine transport (GO:0015872)2.14794789
170photoreceptor cell differentiation (GO:0046530)2.14780814
171eye photoreceptor cell differentiation (GO:0001754)2.14780814
172aromatic amino acid family metabolic process (GO:0009072)2.14607938
173regulation of action potential (GO:0098900)2.14592483
174negative regulation of protein localization to cell surface (GO:2000009)2.13494686
175bile acid biosynthetic process (GO:0006699)2.13008995
176neuron-neuron synaptic transmission (GO:0007270)2.11953464
177preassembly of GPI anchor in ER membrane (GO:0016254)2.11929175
178synaptic transmission, glutamatergic (GO:0035249)2.11304237
179regulation of cardiac muscle contraction (GO:0055117)2.11273819
180dentate gyrus development (GO:0021542)2.11044022
181negative regulation of nitric-oxide synthase activity (GO:0051001)2.10191522
182neuron remodeling (GO:0016322)2.09757136
183negative regulation of neurotransmitter secretion (GO:0046929)2.08170588
184positive regulation of synapse assembly (GO:0051965)2.07901244

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1GBX2_23144817_ChIP-Seq_PC3_Human4.04653590
2ZNF274_21170338_ChIP-Seq_K562_Hela3.56235506
3EZH2_22144423_ChIP-Seq_EOC_Human3.42225637
4ZFP57_27257070_Chip-Seq_ESCs_Mouse2.71595379
5GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.60717507
6TAF15_26573619_Chip-Seq_HEK293_Human2.51024543
7SALL1_21062744_ChIP-ChIP_HESCs_Human2.29276618
8EWS_26573619_Chip-Seq_HEK293_Human2.26405428
9POU3F2_20337985_ChIP-ChIP_501MEL_Human2.25365238
10TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.23627993
11PCGF2_27294783_Chip-Seq_ESCs_Mouse2.15645769
12GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.12907992
13FLI1_27457419_Chip-Seq_LIVER_Mouse2.04988652
14SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.98826433
15HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.98441259
16SUZ12_27294783_Chip-Seq_NPCs_Mouse1.93800546
17P300_19829295_ChIP-Seq_ESCs_Human1.91313709
18SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.89019962
19EED_16625203_ChIP-ChIP_MESCs_Mouse1.88643433
20BMI1_23680149_ChIP-Seq_NPCS_Mouse1.87062189
21JARID2_20064375_ChIP-Seq_MESCs_Mouse1.86841188
22PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.82661985
23FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.81900170
24MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.80857551
25SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.79360202
26CBX2_27304074_Chip-Seq_ESCs_Mouse1.79066924
27SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.77536665
28NFE2_27457419_Chip-Seq_LIVER_Mouse1.77322929
29VDR_22108803_ChIP-Seq_LS180_Human1.76441672
30EZH2_27304074_Chip-Seq_ESCs_Mouse1.76418570
31CTBP1_25329375_ChIP-Seq_LNCAP_Human1.75235669
32EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.73056545
33RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.72771821
34SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.72530400
35PCGF2_27294783_Chip-Seq_NPCs_Mouse1.72140258
36PIAS1_25552417_ChIP-Seq_VCAP_Human1.70604389
37CTBP2_25329375_ChIP-Seq_LNCAP_Human1.69499968
38SMAD4_21799915_ChIP-Seq_A2780_Human1.68976981
39EZH2_27294783_Chip-Seq_NPCs_Mouse1.66126605
40EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.65839056
41NANOG_18555785_Chip-Seq_ESCs_Mouse1.65008691
42TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.63214079
43E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.60072403
44SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.59383299
45HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.59328145
46E2F1_18555785_Chip-Seq_ESCs_Mouse1.58054259
47P53_22387025_ChIP-Seq_ESCs_Mouse1.56979869
48IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.56623904
49CBP_20019798_ChIP-Seq_JUKART_Human1.56623904
50EGR1_23403033_ChIP-Seq_LIVER_Mouse1.55388920
51TP53_22573176_ChIP-Seq_HFKS_Human1.55113579
52CDX2_19796622_ChIP-Seq_MESCs_Mouse1.54750392
53SUZ12_18555785_Chip-Seq_ESCs_Mouse1.54089949
54CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.53627055
55ER_23166858_ChIP-Seq_MCF-7_Human1.52664448
56EZH2_18974828_ChIP-Seq_MESCs_Mouse1.52404834
57RNF2_18974828_ChIP-Seq_MESCs_Mouse1.52404834
58GABP_17652178_ChIP-ChIP_JURKAT_Human1.52329078
59FUS_26573619_Chip-Seq_HEK293_Human1.51216517
60STAT3_18555785_Chip-Seq_ESCs_Mouse1.50426126
61BCAT_22108803_ChIP-Seq_LS180_Human1.49890339
62EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse1.49469790
63JARID2_20075857_ChIP-Seq_MESCs_Mouse1.48254031
64NOTCH1_21737748_ChIP-Seq_TLL_Human1.46599582
65IRF1_19129219_ChIP-ChIP_H3396_Human1.46537850
66IGF1R_20145208_ChIP-Seq_DFB_Human1.44739573
67CMYC_18555785_Chip-Seq_ESCs_Mouse1.44228916
68AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.43275084
69SMAD3_21741376_ChIP-Seq_EPCs_Human1.43050964
70RUNX1_27457419_Chip-Seq_LIVER_Mouse1.42843712
71EZH2_27294783_Chip-Seq_ESCs_Mouse1.42508119
72MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.42288717
73P300_18555785_Chip-Seq_ESCs_Mouse1.41550782
74MTF2_20144788_ChIP-Seq_MESCs_Mouse1.39110912
75UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.38699222
76EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.38246607
77TOP2B_26459242_ChIP-Seq_MCF-7_Human1.37988412
78NANOG_19829295_ChIP-Seq_ESCs_Human1.37854780
79SOX2_19829295_ChIP-Seq_ESCs_Human1.37854780
80NMYC_18555785_Chip-Seq_ESCs_Mouse1.37553149
81SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.37271308
82SOX2_18555785_Chip-Seq_ESCs_Mouse1.36934373
83KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.36838474
84SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.36664192
85AR_21572438_ChIP-Seq_LNCaP_Human1.36275592
86MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.33834191
87OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.32770663
88MYC_18940864_ChIP-ChIP_HL60_Human1.32292484
89STAT3_23295773_ChIP-Seq_U87_Human1.31380972
90RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.29955281
91OCT4_18555785_Chip-Seq_ESCs_Mouse1.29509568
92CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.29270953
93TAL1_26923725_Chip-Seq_HPCs_Mouse1.29250512
94EST1_17652178_ChIP-ChIP_JURKAT_Human1.29172042
95GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.28295770
96SUZ12_27294783_Chip-Seq_ESCs_Mouse1.28285272
97ELK1_19687146_ChIP-ChIP_HELA_Human1.28246765
98KLF5_20875108_ChIP-Seq_MESCs_Mouse1.27983133
99POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.27064993
100TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.27064993
101REST_21632747_ChIP-Seq_MESCs_Mouse1.26701426
102FOXA1_25329375_ChIP-Seq_VCAP_Human1.26423238
103FOXA1_27270436_Chip-Seq_PROSTATE_Human1.26423238
104PU1_27457419_Chip-Seq_LIVER_Mouse1.26267893
105CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.25906734
106PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.25807579
107ZFX_18555785_Chip-Seq_ESCs_Mouse1.25561000
108RNF2_27304074_Chip-Seq_NSC_Mouse1.25450048
109SMAD_19615063_ChIP-ChIP_OVARY_Human1.25372185
110TCF4_22108803_ChIP-Seq_LS180_Human1.24613746
111SMAD1_18555785_Chip-Seq_ESCs_Mouse1.23676182
112CRX_20693478_ChIP-Seq_RETINA_Mouse1.23567220
113AR_25329375_ChIP-Seq_VCAP_Human1.23498833
114RNF2_27304074_Chip-Seq_ESCs_Mouse1.23340311
115TCF4_23295773_ChIP-Seq_U87_Human1.22111225
116KLF4_18555785_Chip-Seq_ESCs_Mouse1.21948991
117FLI1_21867929_ChIP-Seq_TH2_Mouse1.21178948
118VDR_23849224_ChIP-Seq_CD4+_Human1.20965627
119FOXA1_21572438_ChIP-Seq_LNCaP_Human1.20274871
120SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.19948030
121KDM2B_26808549_Chip-Seq_REH_Human1.19942913
122AUTS2_25519132_ChIP-Seq_293T-REX_Human1.19609807
123ESRRB_18555785_Chip-Seq_ESCs_Mouse1.19550181
124DROSHA_22980978_ChIP-Seq_HELA_Human1.19431372
125RUNX2_22187159_ChIP-Seq_PCA_Human1.19290771
126NCOR_22424771_ChIP-Seq_293T_Human1.18287839
127OCT4_21477851_ChIP-Seq_ESCs_Mouse1.18042133
128HTT_18923047_ChIP-ChIP_STHdh_Human1.17181410
129CTCF_18555785_Chip-Seq_ESCs_Mouse1.16795376
130NR3C1_21868756_ChIP-Seq_MCF10A_Human1.16639230
131IRF8_22096565_ChIP-ChIP_GC-B_Human1.15427062
132BP1_19119308_ChIP-ChIP_Hs578T_Human1.14147429
133ETV2_25802403_ChIP-Seq_MESCs_Mouse1.14041084
134TP53_18474530_ChIP-ChIP_U2OS_Human1.13005731
135SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse1.12606871
136PRDM14_20953172_ChIP-Seq_ESCs_Human1.12219199
137BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.09215086
138TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.08762986
139GATA3_21878914_ChIP-Seq_MCF-7_Human1.07791482
140SMAD4_21741376_ChIP-Seq_EPCs_Human1.06515855
141AR_20517297_ChIP-Seq_VCAP_Human1.04770868
142CDX2_22108803_ChIP-Seq_LS180_Human1.04349576
143TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse0.99826037
144CEBPA_26348894_ChIP-Seq_LIVER_Mouse0.98759383

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0005360_urolithiasis3.30815042
2MP0008877_abnormal_DNA_methylation3.25676892
3MP0003880_abnormal_central_pattern3.13064457
4MP0003136_yellow_coat_color2.91173973
5MP0000569_abnormal_digit_pigmentation2.73513585
6MP0001188_hyperpigmentation2.73222390
7MP0006292_abnormal_olfactory_placode2.56057320
8MP0003787_abnormal_imprinting2.43438664
9MP0005085_abnormal_gallbladder_physiolo2.32926758
10MP0005171_absent_coat_pigmentation2.27402391
11MP0004381_abnormal_hair_follicle2.19389467
12MP0005646_abnormal_pituitary_gland2.17000295
13MP0002139_abnormal_hepatobiliary_system2.16527030
14MP0003950_abnormal_plasma_membrane2.15869844
15MP0002837_dystrophic_cardiac_calcinosis2.15355451
16MP0001986_abnormal_taste_sensitivity2.07181341
17MP0005551_abnormal_eye_electrophysiolog2.04813709
18MP0002876_abnormal_thyroid_physiology2.01968113
19MP0005409_darkened_coat_color2.01941258
20MP0005365_abnormal_bile_salt2.00525717
21MP0000566_synostosis1.96370613
22MP0008995_early_reproductive_senescence1.94123000
23MP0001486_abnormal_startle_reflex1.94115801
24MP0006276_abnormal_autonomic_nervous1.89554303
25MP0009745_abnormal_behavioral_response1.86933108
26MP0009046_muscle_twitch1.80264630
27MP0008875_abnormal_xenobiotic_pharmacok1.79543284
28MP0009697_abnormal_copulation1.75595729
29MP0005174_abnormal_tail_pigmentation1.73333950
30MP0008872_abnormal_physiological_respon1.72702053
31MP0002272_abnormal_nervous_system1.70873920
32MP0005423_abnormal_somatic_nervous1.67375056
33MP0001529_abnormal_vocalization1.67299599
34MP0005645_abnormal_hypothalamus_physiol1.65285095
35MP0002638_abnormal_pupillary_reflex1.64568147
36MP0002102_abnormal_ear_morphology1.62507436
37MP0005451_abnormal_body_composition1.58260061
38MP0002735_abnormal_chemical_nociception1.57577632
39MP0004885_abnormal_endolymph1.53747338
40MP0002572_abnormal_emotion/affect_behav1.51879987
41MP0004215_abnormal_myocardial_fiber1.51634607
42MP0004142_abnormal_muscle_tone1.51158034
43MP0002064_seizures1.50595804
44MP0000427_abnormal_hair_cycle1.47365999
45MP0001502_abnormal_circadian_rhythm1.46644373
46MP0001501_abnormal_sleep_pattern1.46137755
47MP0003195_calcinosis1.44932291
48MP0003635_abnormal_synaptic_transmissio1.43396679
49MP0009780_abnormal_chondrocyte_physiolo1.43066503
50MP0002067_abnormal_sensory_capabilities1.41331172
51MP0001485_abnormal_pinna_reflex1.40955521
52MP0002822_catalepsy1.40904214
53MP0001984_abnormal_olfaction1.39989933
54MP0001968_abnormal_touch/_nociception1.36758455
55MP0004742_abnormal_vestibular_system1.35744032
56MP0002163_abnormal_gland_morphology1.35696379
57MP0000015_abnormal_ear_pigmentation1.31461828
58MP0001905_abnormal_dopamine_level1.31137160
59MP0001440_abnormal_grooming_behavior1.29805802
60MP0002063_abnormal_learning/memory/cond1.26449559
61MP0005379_endocrine/exocrine_gland_phen1.25144732
62MP0002736_abnormal_nociception_after1.23892110
63MP0002160_abnormal_reproductive_system1.23693668
64MP0003121_genomic_imprinting1.23625229
65MP0008058_abnormal_DNA_repair1.21807946
66MP0008775_abnormal_heart_ventricle1.21745099
67MP0004130_abnormal_muscle_cell1.20724753
68MP0008260_abnormal_autophagy1.20148800
69MP0004133_heterotaxia1.20027353
70MP0003011_delayed_dark_adaptation1.18940238
71MP0003890_abnormal_embryonic-extraembry1.18647837
72MP0001764_abnormal_homeostasis1.17328548
73MP0005389_reproductive_system_phenotype1.16489907
74MP0003868_abnormal_feces_composition1.15897735
75MP0010386_abnormal_urinary_bladder1.15733627
76MP0005253_abnormal_eye_physiology1.14603055
77MP0006036_abnormal_mitochondrial_physio1.14056294
78MP0002557_abnormal_social/conspecific_i1.12588096
79MP0002734_abnormal_mechanical_nocicepti1.12103386
80MP0004924_abnormal_behavior1.11157562
81MP0005386_behavior/neurological_phenoty1.11157562
82MP0003252_abnormal_bile_duct1.10886898
83MP0004084_abnormal_cardiac_muscle1.09951479
84MP0003646_muscle_fatigue1.09445312
85MP0002095_abnormal_skin_pigmentation1.06947594
86MP0006072_abnormal_retinal_apoptosis1.05605643
87MP0003137_abnormal_impulse_conducting1.03909768
88MP0000372_irregular_coat_pigmentation1.03419426
89MP0004270_analgesia1.02868676
90MP0004085_abnormal_heartbeat1.02360732
91MP0003786_premature_aging1.01158980
92MP0004859_abnormal_synaptic_plasticity1.01018919
93MP0003283_abnormal_digestive_organ1.00890028
94MP0005535_abnormal_body_temperature1.00710605
95MP0000778_abnormal_nervous_system0.99716679
96MP0000026_abnormal_inner_ear0.99071689
97MP0002928_abnormal_bile_duct0.98923420
98MP0005670_abnormal_white_adipose0.98645454
99MP0002938_white_spotting0.98566540
100MP0001963_abnormal_hearing_physiology0.98295211
101MP0002693_abnormal_pancreas_physiology0.94649931
102MP0006035_abnormal_mitochondrial_morpho0.94065389
103MP0004019_abnormal_vitamin_homeostasis0.92362646
104MP0005647_abnormal_sex_gland0.91009764
105MP0003191_abnormal_cellular_cholesterol0.90638834
106MP0004484_altered_response_of0.90562918
107MP0004145_abnormal_muscle_electrophysio0.90160364
108MP0002277_abnormal_respiratory_mucosa0.89810690
109MP0002653_abnormal_ependyma_morphology0.89765407
110MP0005075_abnormal_melanosome_morpholog0.89363870
111MP0003724_increased_susceptibility_to0.87925437
112MP0002138_abnormal_hepatobiliary_system0.87472706
113MP0005671_abnormal_response_to0.85407551
114MP0001919_abnormal_reproductive_system0.85172818
115MP0002332_abnormal_exercise_endurance0.83676186
116MP0005410_abnormal_fertilization0.82580138
117MP0004147_increased_porphyrin_level0.82354623
118MP0005195_abnormal_posterior_eye0.81368385
119MP0000920_abnormal_myelination0.81295017
120MP0003878_abnormal_ear_physiology0.80811839
121MP0005377_hearing/vestibular/ear_phenot0.80811839
122MP0000631_abnormal_neuroendocrine_gland0.80343781
123MP0003567_abnormal_fetal_cardiomyocyte0.80252656
124MP0001929_abnormal_gametogenesis0.79505648
125MP0002229_neurodegeneration0.79448738
126MP0005266_abnormal_metabolism0.79193521
127MP0000383_abnormal_hair_follicle0.79148353
128MP0003698_abnormal_male_reproductive0.78906570
129MP0004510_myositis0.78540978
130MP0005220_abnormal_exocrine_pancreas0.77629499
131MP0002184_abnormal_innervation0.77532136
132MP0003718_maternal_effect0.77079411
133MP0004043_abnormal_pH_regulation0.76729011
134MP0003690_abnormal_glial_cell0.75793870
135MP0010329_abnormal_lipoprotein_level0.73744494
136MP0002210_abnormal_sex_determination0.73429428
137MP0002752_abnormal_somatic_nervous0.72952734
138MP0005620_abnormal_muscle_contractility0.72868563
139MP0001970_abnormal_pain_threshold0.72773782
140MP0005332_abnormal_amino_acid0.72576488
141MP0005084_abnormal_gallbladder_morpholo0.72500930
142MP0002972_abnormal_cardiac_muscle0.72352026
143MP0000230_abnormal_systemic_arterial0.72026040

Predicted human phenotypes

RankGene SetZ-score
1Pancreatic cysts (HP:0001737)3.93447071
2Hyperventilation (HP:0002883)3.77473737
3Febrile seizures (HP:0002373)3.63495000
4Abnormality of midbrain morphology (HP:0002418)3.48166701
5Molar tooth sign on MRI (HP:0002419)3.48166701
6Prolonged partial thromboplastin time (HP:0003645)3.41332512
7Focal motor seizures (HP:0011153)3.33735228
8Nephronophthisis (HP:0000090)3.32122916
9Conjugated hyperbilirubinemia (HP:0002908)3.26570366
10Renal cortical cysts (HP:0000803)3.25576387
11Absent/shortened dynein arms (HP:0200106)3.16255131
12Dynein arm defect of respiratory motile cilia (HP:0012255)3.16255131
13Abnormality of the renal medulla (HP:0100957)2.96971739
14Congenital stationary night blindness (HP:0007642)2.91090642
15Fair hair (HP:0002286)2.87207293
16Abnormal ciliary motility (HP:0012262)2.78118980
17Hypothermia (HP:0002045)2.72262318
18Abolished electroretinogram (ERG) (HP:0000550)2.68618911
19Type II lissencephaly (HP:0007260)2.67515900
20Joint hemorrhage (HP:0005261)2.60761290
21Decreased central vision (HP:0007663)2.58927541
22Blue irides (HP:0000635)2.58409256
23Calf muscle hypertrophy (HP:0008981)2.57407248
24Muscle hypertrophy of the lower extremities (HP:0008968)2.57036495
25Abnormal rod and cone electroretinograms (HP:0008323)2.56368781
26Intrahepatic cholestasis (HP:0001406)2.55931547
27Tubular atrophy (HP:0000092)2.50295745
28Abnormal drinking behavior (HP:0030082)2.46613734
29Polydipsia (HP:0001959)2.46613734
30White forelock (HP:0002211)2.45771068
31Respiratory insufficiency due to defective ciliary clearance (HP:0200073)2.43026762
32Acute necrotizing encephalopathy (HP:0006965)2.42942750
33Congenital sensorineural hearing impairment (HP:0008527)2.42587927
34Epileptic encephalopathy (HP:0200134)2.42225459
35Generalized hypopigmentation of hair (HP:0011358)2.40741225
36Colon cancer (HP:0003003)2.40005927
37Medial flaring of the eyebrow (HP:0010747)2.39300754
38Patchy hypopigmentation of hair (HP:0011365)2.38678276
39Chronic hepatic failure (HP:0100626)2.36220667
40Abnormal hair whorl (HP:0010721)2.35783944
41Pendular nystagmus (HP:0012043)2.35782283
42Osteomalacia (HP:0002749)2.34479322
43Hypoplasia of the fovea (HP:0007750)2.30762488
44Aplasia/Hypoplasia of the fovea (HP:0008060)2.30762488
45Genetic anticipation (HP:0003743)2.30120407
46Septo-optic dysplasia (HP:0100842)2.29474127
47Abnormality of the renal collecting system (HP:0004742)2.29446070
48Chromosomal breakage induced by crosslinking agents (HP:0003221)2.28585262
49Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.27025467
50Abnormality of alanine metabolism (HP:0010916)2.27025467
51Hyperalaninemia (HP:0003348)2.27025467
52Optic disc pallor (HP:0000543)2.26226537
53Atrial fibrillation (HP:0005110)2.25605098
54Large for gestational age (HP:0001520)2.25098868
55Abnormal respiratory motile cilium physiology (HP:0012261)2.24140560
56Thyroiditis (HP:0100646)2.21967867
573-Methylglutaconic aciduria (HP:0003535)2.20803967
58Cystic liver disease (HP:0006706)2.18772578
59Gait imbalance (HP:0002141)2.18006200
60Nephrogenic diabetes insipidus (HP:0009806)2.17741322
61Gaze-evoked nystagmus (HP:0000640)2.17454841
62Cerebral edema (HP:0002181)2.17248907
63Duplicated collecting system (HP:0000081)2.16843009
64Renal Fanconi syndrome (HP:0001994)2.16809080
65Acute encephalopathy (HP:0006846)2.16737319
66Thyroid-stimulating hormone excess (HP:0002925)2.15607873
67Abnormal respiratory epithelium morphology (HP:0012253)2.14667626
68Abnormal respiratory motile cilium morphology (HP:0005938)2.14667626
69Absent rod-and cone-mediated responses on ERG (HP:0007688)2.14367640
70Progressive inability to walk (HP:0002505)2.13437401
71Abnormal mitochondria in muscle tissue (HP:0008316)2.13408643
72Syncope (HP:0001279)2.12574503
73Increased CSF lactate (HP:0002490)2.11158135
74Ketoacidosis (HP:0001993)2.09895358
75Congenital primary aphakia (HP:0007707)2.09834346
76Methylmalonic acidemia (HP:0002912)2.09824143
77Abnormality of macular pigmentation (HP:0008002)2.08853444
78Stomach cancer (HP:0012126)2.08328629
79Hypophosphatemic rickets (HP:0004912)2.08236472
80Progressive macrocephaly (HP:0004481)2.07512443
81Abnormality of methionine metabolism (HP:0010901)2.07430308
82Polyuria (HP:0000103)2.07307546
83Decreased electroretinogram (ERG) amplitude (HP:0000654)2.05689678
84Ketosis (HP:0001946)2.04007064
85Progressive cerebellar ataxia (HP:0002073)2.03345151
86Primary atrial arrhythmia (HP:0001692)2.03138445
87Congenital hepatic fibrosis (HP:0002612)2.02373541
88Abnormality of the renal cortex (HP:0011035)2.01100252
89Aplasia/Hypoplasia of the uvula (HP:0010293)1.98758852
90Inability to walk (HP:0002540)1.97620841
91Abnormality of B cell number (HP:0010975)1.97557097
92Lissencephaly (HP:0001339)1.96968195
93Abnormality of the pons (HP:0007361)1.96676347
94Methylmalonic aciduria (HP:0012120)1.96520973
95Attenuation of retinal blood vessels (HP:0007843)1.95825183
96Optic nerve hypoplasia (HP:0000609)1.95705279
97Mitochondrial inheritance (HP:0001427)1.94824041
98Tubulointerstitial nephritis (HP:0001970)1.94327387
99Absent thumb (HP:0009777)1.92789897
100Abnormality of aromatic amino acid family metabolism (HP:0004338)1.92433540
101Sclerocornea (HP:0000647)1.92431853
102Prolonged QT interval (HP:0001657)1.91308421
103Atonic seizures (HP:0010819)1.91257508
104Broad-based gait (HP:0002136)1.91221237
105Supraventricular tachycardia (HP:0004755)1.89556590
106Abnormality of DNA repair (HP:0003254)1.86916228
107Increased hepatocellular lipid droplets (HP:0006565)1.86059936
108Severe combined immunodeficiency (HP:0004430)1.85458665
109Glycosuria (HP:0003076)1.84025070
110Abnormality of urine glucose concentration (HP:0011016)1.84025070
111Hyperlipoproteinemia (HP:0010980)1.83496852
112Protruding tongue (HP:0010808)1.83272030
113Parakeratosis (HP:0001036)1.82523744
114Congenital, generalized hypertrichosis (HP:0004540)1.82216867
115Anencephaly (HP:0002323)1.80893452
116Hypoplasia of the pons (HP:0012110)1.80880503
117Abnormality of the fovea (HP:0000493)1.80636390
118Stomatitis (HP:0010280)1.80467337
119Abnormality of the calf musculature (HP:0001430)1.80214721
120Confusion (HP:0001289)1.79822352
121Aplasia/Hypoplasia of the tongue (HP:0010295)1.79671643
122Postaxial foot polydactyly (HP:0001830)1.79192535
123Furrowed tongue (HP:0000221)1.78908008
124Enlarged kidneys (HP:0000105)1.78429049
125Abnormality of renal resorption (HP:0011038)1.78082250
126Symptomatic seizures (HP:0011145)1.78032647
127Male pseudohermaphroditism (HP:0000037)1.77570506
128Supraventricular arrhythmia (HP:0005115)1.76566228
129Genital tract atresia (HP:0001827)1.76445862
130Chromsome breakage (HP:0040012)1.75812545
131Microvesicular hepatic steatosis (HP:0001414)1.75794706
132Generalized tonic-clonic seizures (HP:0002069)1.75028977
133Cerebellar dysplasia (HP:0007033)1.74304784
134Hepatic necrosis (HP:0002605)1.74108877
135Absent speech (HP:0001344)1.73797628
136Abnormality of aspartate family amino acid metabolism (HP:0010899)1.73765610
137Vaginal atresia (HP:0000148)1.73647341
138Abnormal biliary tract physiology (HP:0012439)1.73387092
139Bile duct proliferation (HP:0001408)1.73387092
140Submucous cleft hard palate (HP:0000176)1.73137580
141Hypoproteinemia (HP:0003075)1.71607923
142Poor coordination (HP:0002370)1.71258465
143Abnormality of chromosome stability (HP:0003220)1.71232674
144Abnormality of the ileum (HP:0001549)1.71117192
145True hermaphroditism (HP:0010459)1.70098226
146Exercise-induced myalgia (HP:0003738)1.69609587
147Aplasia/Hypoplasia of the spleen (HP:0010451)1.69281190
148Abnormality of incisor morphology (HP:0011063)1.68241871
149Tachypnea (HP:0002789)1.66769190
150Left ventricular hypertrophy (HP:0001712)1.66633245
151Renal tubular dysfunction (HP:0000124)1.66471098
152Aplasia/Hypoplasia of the tibia (HP:0005772)1.66442112
153Abnormality of the axillary hair (HP:0100134)1.66072872
154Abnormality of secondary sexual hair (HP:0009888)1.66072872
155Hypoglycemic seizures (HP:0002173)1.64741241
156Anomalous pulmonary venous return (HP:0010772)1.64623706
157Lipid accumulation in hepatocytes (HP:0006561)1.64585828
158Pancreatic fibrosis (HP:0100732)1.63102176

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CASK4.25839793
2TNIK3.51676659
3INSRR3.38104390
4MAP4K22.84450142
5MAP2K72.67421765
6ACVR1B2.50081514
7AKT32.12260924
8PRPF4B2.07712962
9EPHA41.96731237
10GRK71.96156168
11OBSCN1.81200356
12MUSK1.78704076
13TLK11.78624258
14NTRK31.77200076
15BMPR1B1.77043732
16ZAK1.67491104
17ADRBK21.58413171
18MAP3K41.50614308
19MAPK131.50060685
20STK161.47865987
21BMPR21.47753842
22PKN11.46386727
23GRK11.46372395
24TXK1.43077334
25TIE11.41870865
26BCKDK1.40050249
27NEK61.38281154
28PIK3CA1.33126705
29YES11.32136169
30IRAK31.31785705
31STK391.31501389
32SGK21.30732711
33MKNK21.27275696
34SIK31.25220385
35OXSR11.22419901
36CDK31.21506025
37MAP3K141.21085708
38SGK4941.21068426
39SGK2231.21068426
40CAMKK21.15948941
41EIF2AK21.15543447
42IRAK21.09133371
43MAP2K41.08258262
44TRIM281.05110352
45IRAK11.04665585
46PRKCE1.04450265
47MAP3K121.00539175
48EPHA30.99994569
49CAMK2A0.96921149
50MYLK0.96676562
51MARK10.95728164
52EIF2AK30.95681964
53DAPK20.93479457
54ITK0.92191774
55IRAK40.89421885
56MAPK70.88258779
57NUAK10.88139071
58CAMK2D0.88067426
59BCR0.86718281
60TAOK20.85670123
61BRSK20.85449383
62MAP4K10.85286742
63DYRK20.84296338
64TNK20.83671741
65ERBB40.82985215
66WNK40.82541142
67PHKG10.82149024
68PHKG20.82149024
69MAP3K60.81875997
70SYK0.81731718
71PLK40.81219357
72MST40.80722772
73MAP3K130.79299807
74NTRK20.78906679
75VRK10.78160041
76FGFR20.77750417
77FES0.75298063
78NLK0.74999017
79WNK10.71546215
80IKBKB0.71212038
81TEC0.69529959
82NEK20.68311475
83GRK50.68249611
84MST1R0.68128817
85MAPK150.68008228
86PRKCQ0.67344735
87PRKAA20.67219135
88CAMK2B0.67153461
89TAOK30.67093257
90NME10.66956798
91PNCK0.66273329
92MAPKAPK30.66042586
93PTK2B0.64074022
94SGK10.63559474
95CAMK10.63514469
96PRKG10.61948780
97CSNK1G10.61739361
98MAPK120.61302898
99CSNK1G20.60446461
100PIK3CG0.60150234
101RPS6KA50.59901446
102ERBB30.59805281
103STK110.58053472
104PINK10.57055398
105MKNK10.56708929
106PASK0.56702863
107PRKACA0.56419805
108BLK0.55989195
109STK240.54122515
110PRKCG0.53637219
111STK30.53547551
112TGFBR10.53375115
113CAMK2G0.53188651
114SGK30.52644337
115KIT0.52361291
116CAMK1G0.51374051
117PBK0.50932840
118ADRBK10.49723288
119PLK20.49308851
120STK38L0.47960598
121MAP2K60.47766526
122BTK0.46743586
123CSNK1G30.45813940
124WNK30.45407445
125MAPKAPK50.45147443
126LYN0.44739353
127CCNB10.43571695
128CDC42BPA0.43356333
129CDK190.42918662
130ATR0.41925930
131VRK20.41280222
132PLK30.40239473
133CDK80.39988790
134FRK0.39773287
135LCK0.39624322
136BRD40.39409401
137MARK30.38427997
138CAMK1D0.37076093
139PRKAA10.36973958
140DYRK1A0.36965957
141ATM0.36201494
142CSNK1A10.35364078
143PAK30.33659079
144IKBKE0.33111275
145SRPK10.33086182
146CHUK0.32894663
147CSNK1A1L0.32361842
148TRPM70.31432961
149PRKCA0.31059086

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050332.79196424
2Fatty acid elongation_Homo sapiens_hsa000622.64786306
3Taurine and hypotaurine metabolism_Homo sapiens_hsa004302.50136927
4Primary bile acid biosynthesis_Homo sapiens_hsa001202.29444229
5Homologous recombination_Homo sapiens_hsa034402.10284136
6Oxidative phosphorylation_Homo sapiens_hsa001902.09121363
7Nitrogen metabolism_Homo sapiens_hsa009102.05713664
8Phototransduction_Homo sapiens_hsa047442.02824891
9Fanconi anemia pathway_Homo sapiens_hsa034601.99035233
10Steroid hormone biosynthesis_Homo sapiens_hsa001401.98485733
11Propanoate metabolism_Homo sapiens_hsa006401.95809088
12Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.94750314
13Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.90764174
14Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.86096503
15Caffeine metabolism_Homo sapiens_hsa002321.86056374
16Selenocompound metabolism_Homo sapiens_hsa004501.83228206
17Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.75428253
18Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.72373457
19Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.69772797
20Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.69705378
21Tryptophan metabolism_Homo sapiens_hsa003801.69453081
22Butanoate metabolism_Homo sapiens_hsa006501.68167751
23Taste transduction_Homo sapiens_hsa047421.64554654
24Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.63224312
25Histidine metabolism_Homo sapiens_hsa003401.58825498
26beta-Alanine metabolism_Homo sapiens_hsa004101.58619180
27Peroxisome_Homo sapiens_hsa041461.57202314
28Retinol metabolism_Homo sapiens_hsa008301.56689664
29Morphine addiction_Homo sapiens_hsa050321.52809887
30Tyrosine metabolism_Homo sapiens_hsa003501.43317040
31Intestinal immune network for IgA production_Homo sapiens_hsa046721.42826093
32Complement and coagulation cascades_Homo sapiens_hsa046101.40273030
33Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007601.39412779
34Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004001.38546510
35Steroid biosynthesis_Homo sapiens_hsa001001.38281962
36GABAergic synapse_Homo sapiens_hsa047271.37502751
37RNA polymerase_Homo sapiens_hsa030201.36859760
38ABC transporters_Homo sapiens_hsa020101.35959082
39Basal transcription factors_Homo sapiens_hsa030221.34125400
40Fatty acid degradation_Homo sapiens_hsa000711.33858592
41Phenylalanine metabolism_Homo sapiens_hsa003601.32975206
42RNA degradation_Homo sapiens_hsa030181.32945339
43Serotonergic synapse_Homo sapiens_hsa047261.32855328
44Glutamatergic synapse_Homo sapiens_hsa047241.31689531
45Asthma_Homo sapiens_hsa053101.31132090
46Primary immunodeficiency_Homo sapiens_hsa053401.30415036
47Collecting duct acid secretion_Homo sapiens_hsa049661.27955198
48Fatty acid metabolism_Homo sapiens_hsa012121.25733218
49Alzheimers disease_Homo sapiens_hsa050101.22990972
50Type I diabetes mellitus_Homo sapiens_hsa049401.22779021
51Parkinsons disease_Homo sapiens_hsa050121.20995269
52Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.18964169
53Cardiac muscle contraction_Homo sapiens_hsa042601.18696269
54Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.18198614
55One carbon pool by folate_Homo sapiens_hsa006701.17744774
56Arginine biosynthesis_Homo sapiens_hsa002201.17213928
57Chemical carcinogenesis_Homo sapiens_hsa052041.14945018
58Maturity onset diabetes of the young_Homo sapiens_hsa049501.14887062
59Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.06596927
60Circadian entrainment_Homo sapiens_hsa047131.03792305
61Ether lipid metabolism_Homo sapiens_hsa005651.01572666
62Vitamin digestion and absorption_Homo sapiens_hsa049771.01543036
63Calcium signaling pathway_Homo sapiens_hsa040201.00867264
64Pentose and glucuronate interconversions_Homo sapiens_hsa000401.00616323
65Sulfur metabolism_Homo sapiens_hsa009200.97997800
66Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.96820897
67Insulin secretion_Homo sapiens_hsa049110.92637863
68Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.90746559
69Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.88946772
70Starch and sucrose metabolism_Homo sapiens_hsa005000.88198483
71Autoimmune thyroid disease_Homo sapiens_hsa053200.86872800
72Arginine and proline metabolism_Homo sapiens_hsa003300.86115225
73PPAR signaling pathway_Homo sapiens_hsa033200.85399126
74Staphylococcus aureus infection_Homo sapiens_hsa051500.83443704
75Huntingtons disease_Homo sapiens_hsa050160.82491968
76Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.82310041
77Vitamin B6 metabolism_Homo sapiens_hsa007500.81663688
78Rheumatoid arthritis_Homo sapiens_hsa053230.80827191
79Glycerolipid metabolism_Homo sapiens_hsa005610.79737768
80Linoleic acid metabolism_Homo sapiens_hsa005910.78543101
81Sphingolipid metabolism_Homo sapiens_hsa006000.77197169
82Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.75747489
83Ovarian steroidogenesis_Homo sapiens_hsa049130.74784078
84Olfactory transduction_Homo sapiens_hsa047400.74641193
85Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.74382789
86Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.74123036
87Fat digestion and absorption_Homo sapiens_hsa049750.74069655
88Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.72783303
89Non-homologous end-joining_Homo sapiens_hsa034500.72738801
90Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.72379693
91Amphetamine addiction_Homo sapiens_hsa050310.71904202
92alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.66447089
93Dilated cardiomyopathy_Homo sapiens_hsa054140.66169580
94Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.66045788
95Metabolic pathways_Homo sapiens_hsa011000.64922016
96Synaptic vesicle cycle_Homo sapiens_hsa047210.64514660
97Circadian rhythm_Homo sapiens_hsa047100.63146742
98Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.63105588
99Salivary secretion_Homo sapiens_hsa049700.62906090
100Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.61077547
101SNARE interactions in vesicular transport_Homo sapiens_hsa041300.60129556
102Purine metabolism_Homo sapiens_hsa002300.59864471
103Arachidonic acid metabolism_Homo sapiens_hsa005900.59541752
104Protein export_Homo sapiens_hsa030600.59476226
105Regulation of autophagy_Homo sapiens_hsa041400.58428441
106Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.57069953
107Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.56847686
108Pyruvate metabolism_Homo sapiens_hsa006200.55161062
109Bile secretion_Homo sapiens_hsa049760.54676519
110Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.54426588
111cAMP signaling pathway_Homo sapiens_hsa040240.53652625
112Renin secretion_Homo sapiens_hsa049240.53367021
113Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.53261193
114Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.52527819
115Glycerophospholipid metabolism_Homo sapiens_hsa005640.51446118
116Long-term depression_Homo sapiens_hsa047300.50245553
117Cocaine addiction_Homo sapiens_hsa050300.48556360
118Cholinergic synapse_Homo sapiens_hsa047250.47467280
119Axon guidance_Homo sapiens_hsa043600.46832980
120Fatty acid biosynthesis_Homo sapiens_hsa000610.46435558
121Graft-versus-host disease_Homo sapiens_hsa053320.46158069
122Ribosome_Homo sapiens_hsa030100.44221311
123Allograft rejection_Homo sapiens_hsa053300.43733391
124Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.43229207
125Vascular smooth muscle contraction_Homo sapiens_hsa042700.42202893
126Dorso-ventral axis formation_Homo sapiens_hsa043200.40737503
127Nucleotide excision repair_Homo sapiens_hsa034200.37987618

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