ABHD6

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1epoxygenase P450 pathway (GO:0019373)5.28921763
2synaptic vesicle maturation (GO:0016188)4.07416294
3erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222)4.05267104
4L-phenylalanine catabolic process (GO:0006559)4.05267104
5presynaptic membrane assembly (GO:0097105)3.99725332
6neurotransmitter-gated ion channel clustering (GO:0072578)3.86536035
7sodium ion export (GO:0071436)3.85909792
8omega-hydroxylase P450 pathway (GO:0097267)3.83525930
9fat-soluble vitamin biosynthetic process (GO:0042362)3.75959432
10erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221)3.72707497
11L-phenylalanine metabolic process (GO:0006558)3.72707497
12drug metabolic process (GO:0017144)3.71473359
13neuron cell-cell adhesion (GO:0007158)3.71394388
14presynaptic membrane organization (GO:0097090)3.68380340
15negative regulation of synaptic transmission, GABAergic (GO:0032229)3.63345168
16regulation of triglyceride catabolic process (GO:0010896)3.62318302
17regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act3.61751308
18angiotensin maturation (GO:0002003)3.54900852
19gamma-aminobutyric acid signaling pathway (GO:0007214)3.37961043
20cellular ketone body metabolic process (GO:0046950)3.36812745
21fatty acid elongation (GO:0030497)3.35941510
22synaptic vesicle exocytosis (GO:0016079)3.34525531
23vocalization behavior (GO:0071625)3.33652954
24triglyceride-rich lipoprotein particle remodeling (GO:0034370)3.33244948
25neuronal action potential propagation (GO:0019227)3.31598794
26vitamin transmembrane transport (GO:0035461)3.30850551
27urea metabolic process (GO:0019627)3.29747070
28gamma-aminobutyric acid transport (GO:0015812)3.29301503
29aromatic amino acid family catabolic process (GO:0009074)3.29157585
30glutamate secretion (GO:0014047)3.26106430
31NADH metabolic process (GO:0006734)3.23329751
32nucleobase catabolic process (GO:0046113)3.22546028
33positive regulation of triglyceride lipase activity (GO:0061365)3.21485465
34positive regulation of lipoprotein lipase activity (GO:0051006)3.21485465
35pyrimidine nucleobase catabolic process (GO:0006208)3.17543556
36negative regulation of cholesterol transport (GO:0032375)3.16618605
37negative regulation of sterol transport (GO:0032372)3.16618605
38phospholipid efflux (GO:0033700)3.14626292
39proline transport (GO:0015824)3.13874686
40nitrogen cycle metabolic process (GO:0071941)3.11965919
41high-density lipoprotein particle remodeling (GO:0034375)3.11755356
42lipoprotein transport (GO:0042953)3.11427343
43positive regulation of excitatory postsynaptic membrane potential (GO:2000463)3.10382415
44heme transport (GO:0015886)3.10297579
45pyrimidine-containing compound transmembrane transport (GO:0072531)3.06711429
46regulation of short-term neuronal synaptic plasticity (GO:0048172)3.04295293
47regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)3.04211320
48cellular sodium ion homeostasis (GO:0006883)3.03490220
49regulation of glutamate receptor signaling pathway (GO:1900449)3.03424044
50iron coordination entity transport (GO:1901678)3.02393224
51cellular glucuronidation (GO:0052695)3.02326497
52glutamate receptor signaling pathway (GO:0007215)3.01563999
53protein localization to synapse (GO:0035418)3.00169019
54bile acid biosynthetic process (GO:0006699)2.99131552
55ethanol oxidation (GO:0006069)2.96562660
56urea cycle (GO:0000050)2.94444254
57ionotropic glutamate receptor signaling pathway (GO:0035235)2.93953304
58glyoxylate metabolic process (GO:0046487)2.93579578
59cerebellar granule cell differentiation (GO:0021707)2.93543693
60complement activation, alternative pathway (GO:0006957)2.93280433
61uronic acid metabolic process (GO:0006063)2.92985386
62glucuronate metabolic process (GO:0019585)2.92985386
63neuron-neuron synaptic transmission (GO:0007270)2.92294618
64postsynaptic membrane organization (GO:0001941)2.91875875
65serine family amino acid catabolic process (GO:0009071)2.91841038
66fatty acid beta-oxidation using acyl-CoA oxidase (GO:0033540)2.91624602
67regulation of systemic arterial blood pressure by renin-angiotensin (GO:0003081)2.91552142
68regulation of synaptic vesicle exocytosis (GO:2000300)2.89960971
69ketone body metabolic process (GO:1902224)2.89477451
70regulation of bile acid biosynthetic process (GO:0070857)2.88997680
71embryonic retina morphogenesis in camera-type eye (GO:0060059)2.87881859
72synaptic transmission, glutamatergic (GO:0035249)2.86339843
73regulation of protein activation cascade (GO:2000257)2.85114372
74reverse cholesterol transport (GO:0043691)2.84816961
75coenzyme catabolic process (GO:0009109)2.83695069
76response to histamine (GO:0034776)2.83117342
77glutamate metabolic process (GO:0006536)2.79443186
78very-low-density lipoprotein particle assembly (GO:0034379)2.79312548
79neurotransmitter secretion (GO:0007269)2.77289940
80behavioral response to cocaine (GO:0048148)2.75646274
81bile acid and bile salt transport (GO:0015721)2.74714652
82drug catabolic process (GO:0042737)2.74372593
83mitochondrial electron transport, NADH to ubiquinone (GO:0006120)2.72732485
84regulation of cholesterol esterification (GO:0010872)2.72529529
85sodium ion homeostasis (GO:0055078)2.71848811
86membrane depolarization during cardiac muscle cell action potential (GO:0086012)2.71679659
87glycosphingolipid catabolic process (GO:0046479)2.71585007
88dicarboxylic acid catabolic process (GO:0043649)2.70198485
89G-protein coupled glutamate receptor signaling pathway (GO:0007216)2.69787967
90long-term synaptic potentiation (GO:0060291)2.65435140
91bile acid metabolic process (GO:0008206)2.64982807
92indole-containing compound catabolic process (GO:0042436)2.64846178
93indolalkylamine catabolic process (GO:0046218)2.64846178
94tryptophan catabolic process (GO:0006569)2.64846178
95regulation of complement activation (GO:0030449)2.64557637
96fructose metabolic process (GO:0006000)2.64236901
97amino acid import (GO:0043090)2.63614012
98regulation of synaptic vesicle transport (GO:1902803)2.63391760
99neurotransmitter catabolic process (GO:0042135)2.61124777
100plasma lipoprotein particle remodeling (GO:0034369)2.61054118
101protein-lipid complex remodeling (GO:0034368)2.61054118
102macromolecular complex remodeling (GO:0034367)2.61054118
103acidic amino acid transport (GO:0015800)2.60179265
104cysteine metabolic process (GO:0006534)2.60004166
105peroxisome fission (GO:0016559)2.59932435
106very long-chain fatty acid metabolic process (GO:0000038)2.59623577
107C4-dicarboxylate transport (GO:0015740)2.59506194
108positive regulation of triglyceride metabolic process (GO:0090208)2.59494233
109energy coupled proton transmembrane transport, against electrochemical gradient (GO:0015988)2.59457171
110ATP hydrolysis coupled proton transport (GO:0015991)2.59457171
111regulation of guanylate cyclase activity (GO:0031282)2.59359499
112positive regulation of synapse maturation (GO:0090129)2.59138603
113S-adenosylmethionine metabolic process (GO:0046500)2.58628673
114sulfur amino acid catabolic process (GO:0000098)2.54445798
115startle response (GO:0001964)2.54085059
116potassium ion homeostasis (GO:0055075)2.53944310
117chaperone-mediated protein transport (GO:0072321)2.53181862
118aromatic amino acid family metabolic process (GO:0009072)2.52985308
119synaptic vesicle endocytosis (GO:0048488)2.52583620
120oxidative demethylation (GO:0070989)2.51950640
121alpha-amino acid catabolic process (GO:1901606)2.51813154
122synaptic vesicle docking involved in exocytosis (GO:0016081)2.51798235
123cerebellar Purkinje cell differentiation (GO:0021702)2.51349889
124glycosylceramide metabolic process (GO:0006677)2.50563250
125hormone catabolic process (GO:0042447)2.50504346
126neurotransmitter transport (GO:0006836)2.49740361
127regulation of glutamate secretion (GO:0014048)2.49140957
128neuronal ion channel clustering (GO:0045161)2.48926884
129glycolipid catabolic process (GO:0019377)2.48610884
130tryptophan metabolic process (GO:0006568)2.47944644
131phenylpropanoid metabolic process (GO:0009698)2.47635844
132protein carboxylation (GO:0018214)2.47333514
133peptidyl-glutamic acid carboxylation (GO:0017187)2.47333514
134short-chain fatty acid metabolic process (GO:0046459)2.47010587
135cell communication by electrical coupling involved in cardiac conduction (GO:0086064)2.46853566
136kynurenine metabolic process (GO:0070189)2.45477376
137exogenous drug catabolic process (GO:0042738)2.44906610
138regulation of synaptic transmission, glutamatergic (GO:0051966)2.44232321
139neurotransmitter uptake (GO:0001504)2.44221203
140regulation of neurotransmitter levels (GO:0001505)2.43235357
141acylglycerol homeostasis (GO:0055090)2.43149335
142triglyceride homeostasis (GO:0070328)2.43149335
143ethanol metabolic process (GO:0006067)2.41892089
144positive regulation of calcium ion-dependent exocytosis (GO:0045956)2.41369971
145L-glutamate transport (GO:0015813)2.41162107
146regulation of cholesterol metabolic process (GO:0090181)2.40730926
147regulation of neuronal synaptic plasticity (GO:0048168)2.40671553
148establishment of mitochondrion localization (GO:0051654)2.40538124
149flavonoid metabolic process (GO:0009812)2.40407018
150cellular amino acid catabolic process (GO:0009063)2.39342458
151female mating behavior (GO:0060180)2.38471168
152long-chain fatty acid biosynthetic process (GO:0042759)2.37916069
153cellular potassium ion homeostasis (GO:0030007)2.37716683
154L-amino acid import (GO:0043092)2.35809883
155regulation of excitatory postsynaptic membrane potential (GO:0060079)2.34405966
156biotin metabolic process (GO:0006768)2.32436208
157cholesterol efflux (GO:0033344)2.32032641
158axon ensheathment in central nervous system (GO:0032291)2.31590279
159central nervous system myelination (GO:0022010)2.31590279
160negative regulation of neurotransmitter transport (GO:0051589)2.31261833
161neuromuscular process controlling posture (GO:0050884)2.31181075

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1GBX2_23144817_ChIP-Seq_PC3_Human3.84301861
2EZH2_22144423_ChIP-Seq_EOC_Human3.31215059
3ESR1_17901129_ChIP-ChIP_LIVER_Mouse2.91862170
4TAF15_26573619_Chip-Seq_HEK293_Human2.72566754
5THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse2.58998796
6SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.48988252
7* SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.42076028
8E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.32552876
9MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human2.26268752
10PPARG_19300518_ChIP-PET_3T3-L1_Mouse2.24081122
11JARID2_20064375_ChIP-Seq_MESCs_Mouse2.23423269
12TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.22252396
13VDR_22108803_ChIP-Seq_LS180_Human2.17390266
14RXR_22158963_ChIP-Seq_LIVER_Mouse2.12827543
15ZFP57_27257070_Chip-Seq_ESCs_Mouse2.12388917
16REST_21632747_ChIP-Seq_MESCs_Mouse2.07453051
17* SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.03831389
18CTBP1_25329375_ChIP-Seq_LNCAP_Human2.03545528
19FOXO1_23066095_ChIP-Seq_LIVER_Mouse2.02769361
20CTBP2_25329375_ChIP-Seq_LNCAP_Human1.98820929
21* SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.97565284
22* SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.95549301
23RNF2_18974828_ChIP-Seq_MESCs_Mouse1.94999121
24EZH2_18974828_ChIP-Seq_MESCs_Mouse1.94999121
25MTF2_20144788_ChIP-Seq_MESCs_Mouse1.94263315
26JARID2_20075857_ChIP-Seq_MESCs_Mouse1.93001318
27NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.92446835
28EZH2_27304074_Chip-Seq_ESCs_Mouse1.91475941
29GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.90033909
30EED_16625203_ChIP-ChIP_MESCs_Mouse1.89028171
31SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.88505857
32GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.88061750
33EGR1_23403033_ChIP-Seq_LIVER_Mouse1.78007668
34REST_18959480_ChIP-ChIP_MESCs_Mouse1.71082230
35* LXR_22158963_ChIP-Seq_LIVER_Mouse1.67272543
36P300_19829295_ChIP-Seq_ESCs_Human1.64767968
37PIAS1_25552417_ChIP-Seq_VCAP_Human1.62826039
38DNAJC2_21179169_ChIP-ChIP_NT2_Human1.58843820
39SMAD4_21799915_ChIP-Seq_A2780_Human1.57309550
40* SUZ12_27294783_Chip-Seq_ESCs_Mouse1.55730367
41POU3F2_20337985_ChIP-ChIP_501MEL_Human1.53756248
42EZH2_27294783_Chip-Seq_ESCs_Mouse1.51539224
43HTT_18923047_ChIP-ChIP_STHdh_Human1.48416335
44EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.48256106
45* PPARA_22158963_ChIP-Seq_LIVER_Mouse1.47927088
46* RNF2_27304074_Chip-Seq_ESCs_Mouse1.41153048
47BMI1_23680149_ChIP-Seq_NPCS_Mouse1.40839689
48* SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.39032274
49SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.38335019
50* UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.36875587
51ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.36832077
52CBX2_27304074_Chip-Seq_ESCs_Mouse1.36123992
53FUS_26573619_Chip-Seq_HEK293_Human1.33546234
54AR_21572438_ChIP-Seq_LNCaP_Human1.32178769
55SRY_22984422_ChIP-ChIP_TESTIS_Rat1.31417997
56* RARB_27405468_Chip-Seq_BRAIN_Mouse1.31403307
57AR_25329375_ChIP-Seq_VCAP_Human1.30722183
58OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.28298926
59SMAD3_21741376_ChIP-Seq_EPCs_Human1.26932805
60PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.26592317
61TOP2B_26459242_ChIP-Seq_MCF-7_Human1.25647923
62ERG_21242973_ChIP-ChIP_JURKAT_Human1.24238051
63AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.21517688
64DROSHA_22980978_ChIP-Seq_HELA_Human1.20889882
65SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.20163568
66FOXA2_19822575_ChIP-Seq_HepG2_Human1.19507285
67NR3C1_23031785_ChIP-Seq_PC12_Mouse1.19439406
68CDX2_20551321_ChIP-Seq_CACO-2_Human1.19015510
69FLI1_27457419_Chip-Seq_LIVER_Mouse1.18687247
70NR1I2_20693526_ChIP-Seq_LIVER_Mouse1.17773767
71RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.17737038
72ZNF274_21170338_ChIP-Seq_K562_Hela1.17228522
73BCAT_22108803_ChIP-Seq_LS180_Human1.16612111
74IKZF1_21737484_ChIP-ChIP_HCT116_Human1.16510631
75TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.12973424
76STAT3_23295773_ChIP-Seq_U87_Human1.12871865
77NANOG_18555785_Chip-Seq_ESCs_Mouse1.09878362
78RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.08822365
79SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.05672513
80SOX2_21211035_ChIP-Seq_LN229_Gbm1.04820418
81ER_23166858_ChIP-Seq_MCF-7_Human1.03161711
82SMAD_19615063_ChIP-ChIP_OVARY_Human1.03155937
83* TET1_21490601_ChIP-Seq_MESCs_Mouse1.03086449
84* LXR_22292898_ChIP-Seq_THP-1_Human1.02687582
85PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse1.02594719
86TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.01069184
87RNF2_27304074_Chip-Seq_NSC_Mouse1.01006667
88CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.00994280
89CTCF_27219007_Chip-Seq_Bcells_Human1.00623873
90MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.00560201
91CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.00510751
92FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse1.00403479
93BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.99753799
94TCF7L2_21901280_ChIP-Seq_H4IIE_Rat0.99694637
95* ZFP322A_24550733_ChIP-Seq_MESCs_Mouse0.99024018
96MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.98616480
97* RUNX2_22187159_ChIP-Seq_PCA_Human0.98581079
98* PHC1_16625203_ChIP-ChIP_MESCs_Mouse0.98421769
99PRDM14_20953172_ChIP-Seq_ESCs_Human0.98404970
100EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse0.98283872
101WT1_25993318_ChIP-Seq_PODOCYTE_Human0.98077730
102PCGF2_27294783_Chip-Seq_ESCs_Mouse0.97881865
103NR3C1_21868756_ChIP-Seq_MCF10A_Human0.97342633
104TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human0.97251284
105CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons0.97166569
106CDX2_19796622_ChIP-Seq_MESCs_Mouse0.97165556
107* HNF4A_19822575_ChIP-Seq_HepG2_Human0.96820963
108TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse0.96493043
109ARNT_22903824_ChIP-Seq_MCF-7_Human0.95732608
110JUN_21703547_ChIP-Seq_K562_Human0.94606865
111TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.94004909
112CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.93492932
113SUZ12_27294783_Chip-Seq_NPCs_Mouse0.93344967
114* RNF2_16625203_ChIP-ChIP_MESCs_Mouse0.92982703
115* RING1B_27294783_Chip-Seq_ESCs_Mouse0.92745804
116KDM2B_26808549_Chip-Seq_REH_Human0.92593908
117* PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse0.91550889
118SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.91188955
119PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse0.90614008
120P53_22387025_ChIP-Seq_ESCs_Mouse0.90285819
121TRIM28_21343339_ChIP-Seq_HEK293_Human0.90232102
122TCF4_23295773_ChIP-Seq_U87_Human0.90174423
123KDM2B_26808549_Chip-Seq_K562_Human0.89396280
124P53_22127205_ChIP-Seq_FIBROBLAST_Human0.89210121
125AHR_22903824_ChIP-Seq_MCF-7_Human0.88324925
126CEBPB_23403033_ChIP-Seq_LIVER_Mouse0.87106917
127* EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human0.86994287
128ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse0.86259105
129KAP1_22055183_ChIP-Seq_ESCs_Mouse0.86151981
130E2F1_18555785_Chip-Seq_ESCs_Mouse0.85917470
131SMC4_20622854_ChIP-Seq_HELA_Human0.85853789
132RUNX1_27457419_Chip-Seq_LIVER_Mouse0.85562527
133SMAD3_22036565_ChIP-Seq_ESCs_Mouse0.85117815
134VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human0.84258947
135CBP_21632823_ChIP-Seq_H3396_Human0.83061766
136AR_19668381_ChIP-Seq_PC3_Human0.82048288
137TP53_18474530_ChIP-ChIP_U2OS_Human0.81935119
138OLIG2_26023283_ChIP-Seq_AINV15_Mouse0.81705278
139SMAD3_21741376_ChIP-Seq_ESCs_Human0.80136408
140RBPJ_22232070_ChIP-Seq_NCS_Mouse0.76615986
141OCT4_19829295_ChIP-Seq_ESCs_Human0.76152453
142LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.75996850
143CTCF_20526341_ChIP-Seq_ESCs_Human0.74913385
144* MYC_19915707_ChIP-ChIP_AK7_Human0.74802810
145SMAD4_21741376_ChIP-Seq_HESCs_Human0.74720753
146TAL1_26923725_Chip-Seq_HPCs_Mouse0.74319005

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003880_abnormal_central_pattern4.57108023
2MP0005360_urolithiasis3.83230396
3MP0002139_abnormal_hepatobiliary_system3.50671161
4MP0004859_abnormal_synaptic_plasticity3.24641099
5MP0008875_abnormal_xenobiotic_pharmacok3.23702796
6MP0005085_abnormal_gallbladder_physiolo3.11508768
7MP0005365_abnormal_bile_salt2.90838586
8MP0002822_catalepsy2.69541242
9MP0003635_abnormal_synaptic_transmissio2.67713199
10MP0009745_abnormal_behavioral_response2.49545750
11MP0004270_analgesia2.45314581
12MP0002064_seizures2.40817139
13MP0001968_abnormal_touch/_nociception2.25995650
14MP0002736_abnormal_nociception_after2.23094164
15MP0009046_muscle_twitch2.23043862
16MP0002063_abnormal_learning/memory/cond2.15544222
17MP0003329_amyloid_beta_deposits2.14868579
18MP0002272_abnormal_nervous_system2.12296642
19MP0001486_abnormal_startle_reflex2.05859752
20MP0002572_abnormal_emotion/affect_behav2.04873889
21MP0000920_abnormal_myelination2.01831032
22MP0002876_abnormal_thyroid_physiology2.01634317
23MP0001440_abnormal_grooming_behavior1.99780301
24MP0001501_abnormal_sleep_pattern1.93703764
25MP0009840_abnormal_foam_cell1.93075496
26MP0003183_abnormal_peptide_metabolism1.92330893
27MP0010329_abnormal_lipoprotein_level1.89260928
28MP0001529_abnormal_vocalization1.87540056
29MP0002734_abnormal_mechanical_nocicepti1.77455842
30MP0009780_abnormal_chondrocyte_physiolo1.76327395
31MP0003879_abnormal_hair_cell1.75245033
32MP0005646_abnormal_pituitary_gland1.74040280
33MP0001984_abnormal_olfaction1.68530693
34MP0005058_abnormal_lysosome_morphology1.65863213
35MP0005332_abnormal_amino_acid1.63155775
36MP0002837_dystrophic_cardiac_calcinosis1.63118427
37MP0002067_abnormal_sensory_capabilities1.57228082
38MP0003195_calcinosis1.56645346
39MP0004043_abnormal_pH_regulation1.54855262
40MP0005409_darkened_coat_color1.46643815
41MP0005451_abnormal_body_composition1.46300006
42MP0003634_abnormal_glial_cell1.44829686
43MP0001905_abnormal_dopamine_level1.42918086
44MP0002653_abnormal_ependyma_morphology1.39326857
45MP0006276_abnormal_autonomic_nervous1.36435883
46MP0002735_abnormal_chemical_nociception1.34311138
47MP0002138_abnormal_hepatobiliary_system1.33383609
48MP0002733_abnormal_thermal_nociception1.32811956
49MP0004142_abnormal_muscle_tone1.31517532
50MP0001666_abnormal_nutrient_absorption1.28176327
51MP0001970_abnormal_pain_threshold1.27645150
52MP0005551_abnormal_eye_electrophysiolog1.27191415
53MP0005670_abnormal_white_adipose1.26744776
54MP0003075_altered_response_to1.24735157
55MP0003172_abnormal_lysosome_physiology1.21938229
56MP0004885_abnormal_endolymph1.21451462
57MP0001502_abnormal_circadian_rhythm1.21224438
58MP0000604_amyloidosis1.20131314
59MP0003191_abnormal_cellular_cholesterol1.18945173
60MP0003718_maternal_effect1.18422930
61MP0003806_abnormal_nucleotide_metabolis1.17492347
62MP0002118_abnormal_lipid_homeostasis1.17114365
63MP0003632_abnormal_nervous_system1.16985232
64MP0004019_abnormal_vitamin_homeostasis1.15743814
65MP0002557_abnormal_social/conspecific_i1.15741964
66MP0001764_abnormal_homeostasis1.14602579
67MP0002971_abnormal_brown_adipose1.13664042
68MP0005386_behavior/neurological_phenoty1.12504134
69MP0004924_abnormal_behavior1.12504134
70MP0005423_abnormal_somatic_nervous1.11833134
71MP0008260_abnormal_autophagy1.10924406
72MP0004811_abnormal_neuron_physiology1.10278026
73MP0001661_extended_life_span1.08960537
74MP0000013_abnormal_adipose_tissue1.07734433
75MP0003690_abnormal_glial_cell1.05421325
76MP0003252_abnormal_bile_duct1.03124121
77MP0002066_abnormal_motor_capabilities/c1.01634782
78MP0005535_abnormal_body_temperature1.01532038
79MP0009697_abnormal_copulation1.01158432
80MP0002184_abnormal_innervation1.01155649
81MP0008872_abnormal_physiological_respon1.00563545
82MP0001188_hyperpigmentation1.00373985
83MP0002638_abnormal_pupillary_reflex0.99306478
84MP0003633_abnormal_nervous_system0.98824032
85MP0003787_abnormal_imprinting0.97204666
86MP0001963_abnormal_hearing_physiology0.96499737
87MP0003868_abnormal_feces_composition0.96481012
88MP0002229_neurodegeneration0.95756669
89MP0000778_abnormal_nervous_system0.91432320
90MP0004742_abnormal_vestibular_system0.90421582
91MP0003631_nervous_system_phenotype0.88176816
92MP0008569_lethality_at_weaning0.87271560
93MP0005645_abnormal_hypothalamus_physiol0.84595666
94MP0005171_absent_coat_pigmentation0.82212757
95MP0006035_abnormal_mitochondrial_morpho0.82146904
96MP0010386_abnormal_urinary_bladder0.81595798
97MP0002069_abnormal_eating/drinking_beha0.81290816
98MP0005584_abnormal_enzyme/coenzyme_acti0.81163638
99MP0002882_abnormal_neuron_morphology0.79218577
100MP0002254_reproductive_system_inflammat0.78775180
101MP0002909_abnormal_adrenal_gland0.78536984
102MP0001485_abnormal_pinna_reflex0.78138807
103MP0005377_hearing/vestibular/ear_phenot0.77916441
104MP0003878_abnormal_ear_physiology0.77916441
105MP0005084_abnormal_gallbladder_morpholo0.77660064
106MP0000609_abnormal_liver_physiology0.76718310
107MP0000230_abnormal_systemic_arterial0.75107933
108MP0003122_maternal_imprinting0.74742797
109MP0005636_abnormal_mineral_homeostasis0.74233064
110MP0004147_increased_porphyrin_level0.73878254
111MP0002090_abnormal_vision0.73746404
112MP0006036_abnormal_mitochondrial_physio0.72865536
113MP0000015_abnormal_ear_pigmentation0.72855841
114MP0000955_abnormal_spinal_cord0.71975562
115MP0005166_decreased_susceptibility_to0.71728251
116MP0001664_abnormal_digestion0.71202510
117MP0008874_decreased_physiological_sensi0.70590508
118MP0009643_abnormal_urine_homeostasis0.70506113
119MP0005257_abnormal_intraocular_pressure0.70332534
120MP0000026_abnormal_inner_ear0.69805264
121MP0005379_endocrine/exocrine_gland_phen0.69734346
122MP0004085_abnormal_heartbeat0.68065217
123MP0002152_abnormal_brain_morphology0.67183840
124MP0003011_delayed_dark_adaptation0.65592296
125MP0003123_paternal_imprinting0.65510008
126MP0000566_synostosis0.65311376

Predicted human phenotypes

RankGene SetZ-score
1Focal motor seizures (HP:0011153)6.15007424
2Hyperventilation (HP:0002883)4.33369662
3Abnormality of glutamine family amino acid metabolism (HP:0010902)4.33022641
4Complement deficiency (HP:0004431)4.11209749
5Atonic seizures (HP:0010819)3.97504219
6Action tremor (HP:0002345)3.94229721
7Supranuclear gaze palsy (HP:0000605)3.92694357
8Systemic lupus erythematosus (HP:0002725)3.78206807
9Hyperglycinemia (HP:0002154)3.69974231
10Abnormality of aromatic amino acid family metabolism (HP:0004338)3.68515385
11Epileptic encephalopathy (HP:0200134)3.65432562
12Prolonged partial thromboplastin time (HP:0003645)3.53806750
13Focal seizures (HP:0007359)3.32993139
14Hyperlipoproteinemia (HP:0010980)3.25498747
15Absence seizures (HP:0002121)3.15649910
16Myokymia (HP:0002411)3.15563353
17Hypobetalipoproteinemia (HP:0003563)3.15359015
18Dialeptic seizures (HP:0011146)3.14091773
19Ankle clonus (HP:0011448)3.12585775
20Abnormality of complement system (HP:0005339)3.09536685
21Intrahepatic cholestasis (HP:0001406)3.08315582
22Neurofibrillary tangles (HP:0002185)3.07204004
23Hydroxyprolinuria (HP:0003080)3.03272689
24Abnormality of proline metabolism (HP:0010907)3.03272689
25Hyperglycinuria (HP:0003108)3.01658523
26Abnormality of glycine metabolism (HP:0010895)2.99894493
27Abnormality of serine family amino acid metabolism (HP:0010894)2.99894493
28Febrile seizures (HP:0002373)2.96443520
29Xanthomatosis (HP:0000991)2.95828467
30Acute encephalopathy (HP:0006846)2.94522982
31Confusion (HP:0001289)2.92091319
32Abnormality of glycolysis (HP:0004366)2.91049385
33Increased serum pyruvate (HP:0003542)2.91049385
34Acute necrotizing encephalopathy (HP:0006965)2.91037669
35Abnormality of glycolipid metabolism (HP:0010969)2.90621347
36Abnormality of liposaccharide metabolism (HP:0010968)2.90621347
37Abnormality of glycosphingolipid metabolism (HP:0004343)2.90621347
38Gout (HP:0001997)2.90382425
39Mutism (HP:0002300)2.88831118
40Vacuolated lymphocytes (HP:0001922)2.88649188
41Cerebral inclusion bodies (HP:0100314)2.80588653
42Deep venous thrombosis (HP:0002625)2.73580496
43Retinal atrophy (HP:0001105)2.71917849
44Generalized tonic-clonic seizures (HP:0002069)2.69601357
45Abnormal mitochondria in muscle tissue (HP:0008316)2.68605889
46Visual hallucinations (HP:0002367)2.68102429
47Glomerulonephritis (HP:0000099)2.67253841
48Cerebral edema (HP:0002181)2.62201876
49Lethargy (HP:0001254)2.53874351
50Limb dystonia (HP:0002451)2.52780941
51Delusions (HP:0000746)2.52326209
52Status epilepticus (HP:0002133)2.50396792
53Intention tremor (HP:0002080)2.47790239
54Abnormality of the corticospinal tract (HP:0002492)2.46945564
55Progressive macrocephaly (HP:0004481)2.45432644
56Ketosis (HP:0001946)2.37598554
57Abnormality of serum amino acid levels (HP:0003112)2.35321755
58Neuronal loss in central nervous system (HP:0002529)2.34194496
59Polyphagia (HP:0002591)2.31732832
60Hyperammonemia (HP:0001987)2.31573549
61Spastic gait (HP:0002064)2.30415103
62Hypolipoproteinemia (HP:0010981)2.27318887
63Epileptiform EEG discharges (HP:0011182)2.25397543
64Conjugated hyperbilirubinemia (HP:0002908)2.25305165
65Mitochondrial inheritance (HP:0001427)2.25180559
66Degeneration of the lateral corticospinal tracts (HP:0002314)2.25143435
67Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)2.25143435
68Progressive cerebellar ataxia (HP:0002073)2.24778604
69Abnormality of monocarboxylic acid metabolism (HP:0010996)2.23865526
70Sensorimotor neuropathy (HP:0007141)2.22549694
71Absent speech (HP:0001344)2.19845703
72Abnormal gallbladder physiology (HP:0012438)2.17093274
73Cholecystitis (HP:0001082)2.17093274
74Oligodactyly (hands) (HP:0001180)2.14134563
75Malnutrition (HP:0004395)2.13914437
76Pheochromocytoma (HP:0002666)2.13070256
77Metabolic alkalosis (HP:0200114)2.12405243
78Amblyopia (HP:0000646)2.11717034
79Peripheral hypomyelination (HP:0007182)2.11273328
80Abnormality of aspartate family amino acid metabolism (HP:0010899)2.09061877
81Abnormality of methionine metabolism (HP:0010901)2.08435255
82Generalized myoclonic seizures (HP:0002123)2.08359100
83Dysdiadochokinesis (HP:0002075)2.08154180
84Spastic paraparesis (HP:0002313)2.07385316
85Abnormality of the lower motor neuron (HP:0002366)2.07011112
86Dysmetria (HP:0001310)2.06632803
87Hepatocellular necrosis (HP:0001404)2.05996708
88Apathy (HP:0000741)2.05842457
89Increased CSF lactate (HP:0002490)2.05264226
90Skin nodule (HP:0200036)2.05216423
91Abnormality of the level of lipoprotein cholesterol (HP:0010979)2.04070927
92EEG with generalized epileptiform discharges (HP:0011198)2.03669930
93Inability to walk (HP:0002540)2.01990479
94Methylmalonic aciduria (HP:0012120)2.01112110
95Fat malabsorption (HP:0002630)2.00477337
96Gait imbalance (HP:0002141)2.00419085
97Dementia (HP:0000726)2.00076083
98Ketoacidosis (HP:0001993)1.99694063
99Increased cerebral lipofuscin (HP:0011813)1.99668526
100Cerebral hemorrhage (HP:0001342)1.99441536
101Split foot (HP:0001839)1.99297603
102Truncal ataxia (HP:0002078)1.99278235
103Steatorrhea (HP:0002570)1.96826163
104Diminished motivation (HP:0000745)1.96791048
105Amyloidosis (HP:0011034)1.95952722
106Hepatic necrosis (HP:0002605)1.94757408
107Hand muscle atrophy (HP:0009130)1.93339229
108Alkalosis (HP:0001948)1.93135815
109Synostosis involving the elbow (HP:0003938)1.93107519
110Humeroradial synostosis (HP:0003041)1.93107519
111Excessive salivation (HP:0003781)1.92870493
112Drooling (HP:0002307)1.92870493
113Decreased circulating renin level (HP:0003351)1.92535664
114Torticollis (HP:0000473)1.92410749
115Irritability (HP:0000737)1.91938949
116Neuroendocrine neoplasm (HP:0100634)1.91605508
117Ulnar claw (HP:0001178)1.91504449
118Congenital primary aphakia (HP:0007707)1.91278531
119Clonus (HP:0002169)1.90400999
120CNS demyelination (HP:0007305)1.90225931
121Broad-based gait (HP:0002136)1.90070052
122Methylmalonic acidemia (HP:0002912)1.89636142
123Thickened helices (HP:0000391)1.89608696
124Brushfield spots (HP:0001088)1.89255999
125Abnormality of the periventricular white matter (HP:0002518)1.88762126
126Hemiparesis (HP:0001269)1.88290961
127Lactic acidosis (HP:0003128)1.87729850
128Tetraplegia (HP:0002445)1.87161421
129Hypsarrhythmia (HP:0002521)1.86920570
130Hypoalphalipoproteinemia (HP:0003233)1.86751033
131Metabolic acidosis (HP:0001942)1.85949447
132Abnormality of sulfur amino acid metabolism (HP:0004339)1.85688168
133Poor suck (HP:0002033)1.85250145
134Abnormal eating behavior (HP:0100738)1.85129901
135Medial flaring of the eyebrow (HP:0010747)1.85019715
136Global brain atrophy (HP:0002283)1.84407152
137Depression (HP:0000716)1.83380828
138Scanning speech (HP:0002168)1.82957338
139Paraparesis (HP:0002385)1.82946594
140Anxiety (HP:0000739)1.82339022
141Abnormality of the intrinsic pathway (HP:0010989)1.81106935
142Fair hair (HP:0002286)1.80336845
143Joint hemorrhage (HP:0005261)1.80195797
144Impaired vibration sensation in the lower limbs (HP:0002166)1.79406419
145Abnormality of binocular vision (HP:0011514)1.79137732
146Diplopia (HP:0000651)1.79137732
147Hypercholesterolemia (HP:0003124)1.78195646
148Loss of speech (HP:0002371)1.77946452
149Dicarboxylic aciduria (HP:0003215)1.77108682
150Abnormality of dicarboxylic acid metabolism (HP:0010995)1.77108682
151Focal dystonia (HP:0004373)1.76782994
152Epidermoid cyst (HP:0200040)1.74647124
153Postural instability (HP:0002172)1.72546040
154Hyperaldosteronism (HP:0000859)1.70814876
155Dysostosis multiplex (HP:0000943)1.69429949
156Increased circulating renin level (HP:0000848)1.69315718

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CASK5.18037360
2EPHA44.32175162
3NTRK33.60968533
4AKT32.82056860
5MAP3K42.62226563
6MAP2K72.56508445
7MAP3K122.33204411
8PRKD32.18463268
9OXSR12.12238134
10MAP3K92.09582423
11CAMKK22.08784157
12MAP2K42.04974784
13DAPK22.01922299
14RIPK41.72335262
15CAMKK11.69862062
16PLK21.69517727
17CDK191.65578513
18BMPR21.57265675
19UHMK11.56051310
20GRK51.54896934
21NME11.53607156
22TNIK1.53286057
23RIPK11.47999174
24ACVR1B1.46224491
25BCKDK1.43371548
26PRKCG1.39884716
27STK391.33939174
28MINK11.33007170
29PINK11.32534456
30PRPF4B1.29937974
31EPHB21.28973023
32INSRR1.28908051
33PDK31.28623445
34PDK41.28623445
35DAPK11.27602151
36MAP3K111.26981317
37CAMK2B1.26258699
38CAMK2A1.25471689
39ARAF1.21778034
40CCNB11.21222238
41PNCK1.19752730
42NTRK21.18506993
43SGK4941.17117074
44SGK2231.17117074
45MUSK1.16565577
46BRAF1.15895904
47SIK21.14745826
48ERN11.11378700
49CAMK1G1.10685699
50KSR21.10638615
51ERBB41.10211603
52NTRK11.08769471
53MST1R1.04973287
54PDK21.01192887
55CDK51.00191310
56TYRO30.98720269
57STK160.94459598
58PTK2B0.94276508
59MST40.94157313
60PAK60.92889486
61PRKCE0.92374689
62BCR0.91079780
63CAMK2G0.90184192
64TRIM280.89621541
65PRKG20.88666397
66TSSK60.87314438
67ICK0.85913368
68LIMK10.85212576
69PIM20.84371299
70FGR0.84086311
71ABL20.83545282
72CAMK2D0.83068106
73CDK80.82789400
74CDK11A0.81679250
75FER0.80743091
76MARK10.80373317
77LATS20.79882680
78CDK30.79838043
79SGK20.79525830
80WNK30.75891635
81DDR20.75601515
82DYRK1A0.75450427
83WNK40.75237863
84BMPR1B0.74767100
85LMTK20.74307549
86GRK10.73466764
87KSR10.72649228
88STK110.72039268
89GRK70.71864392
90CAMK10.70763620
91BUB10.70734893
92ROCK20.70495768
93CSNK1G20.69253691
94STK38L0.66944556
95TESK20.65763112
96PDPK10.65271148
97CAMK1D0.64846914
98TESK10.64819875
99PRKACG0.63877482
100MAPK120.62296246
101MAPK130.61505534
102PKN10.59544933
103MAP2K10.59265912
104MET0.57169381
105FRK0.56401985
106PAK30.56061308
107PRKCH0.55765199
108STK380.54388386
109CDK180.52519588
110PRKACA0.51007125
111CDK150.50305920
112SRC0.50273386
113CDK140.49315396
114CAMK40.49272277
115NEK60.49252213
116FYN0.49033392
117FGFR20.48683500
118RPS6KA30.47966175
119PHKG10.47781216
120PHKG20.47781216
121DYRK1B0.47696884
122DAPK30.47595616
123RPS6KA20.47356914
124SGK30.45363979
125FES0.45287237
126GRK60.44585030
127MAPK70.43991110
128MKNK20.43951362
129PRKCA0.43620421
130MAPK150.43462805
131MYLK0.42670434
132SGK10.42644172
133CSNK1G30.42580152
134PRKCZ0.41592536
135PDK10.41167950
136MAP3K20.41163032
137MAPKAPK50.40686638
138CSNK1A10.40349680

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050332.75608810
2Vitamin B6 metabolism_Homo sapiens_hsa007502.70584332
3Primary bile acid biosynthesis_Homo sapiens_hsa001202.41778619
4Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004002.32369884
5Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010402.07692037
6Butanoate metabolism_Homo sapiens_hsa006502.05715969
7Taurine and hypotaurine metabolism_Homo sapiens_hsa004302.05337612
8Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006302.05022562
9Sulfur metabolism_Homo sapiens_hsa009201.91040914
10Collecting duct acid secretion_Homo sapiens_hsa049661.87673877
11Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.86853717
12Oxidative phosphorylation_Homo sapiens_hsa001901.84312136
13Synaptic vesicle cycle_Homo sapiens_hsa047211.83623534
14Arginine biosynthesis_Homo sapiens_hsa002201.75345781
15Fatty acid elongation_Homo sapiens_hsa000621.73716805
16Nitrogen metabolism_Homo sapiens_hsa009101.70879302
17Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.67541537
18GABAergic synapse_Homo sapiens_hsa047271.64703759
19* Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.57872103
20Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.48073290
21Pyruvate metabolism_Homo sapiens_hsa006201.47140612
22Propanoate metabolism_Homo sapiens_hsa006401.46725156
23Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.44104601
24Histidine metabolism_Homo sapiens_hsa003401.43274589
25Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002501.39781113
26Vitamin digestion and absorption_Homo sapiens_hsa049771.37902468
27Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.36327495
28Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.35296956
29Glutamatergic synapse_Homo sapiens_hsa047241.32648035
30Carbohydrate digestion and absorption_Homo sapiens_hsa049731.31739019
31Fatty acid degradation_Homo sapiens_hsa000711.29408546
32Tryptophan metabolism_Homo sapiens_hsa003801.28999087
33Amphetamine addiction_Homo sapiens_hsa050311.27584187
34Morphine addiction_Homo sapiens_hsa050321.25334315
35Cysteine and methionine metabolism_Homo sapiens_hsa002701.23283537
36Fatty acid metabolism_Homo sapiens_hsa012121.23165431
37Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.22658405
38Bile secretion_Homo sapiens_hsa049761.22394410
39Starch and sucrose metabolism_Homo sapiens_hsa005001.21818993
40Steroid hormone biosynthesis_Homo sapiens_hsa001401.21816451
41Peroxisome_Homo sapiens_hsa041461.18098456
42Circadian entrainment_Homo sapiens_hsa047131.18008224
43Steroid biosynthesis_Homo sapiens_hsa001001.15992566
442-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.15557857
45Chemical carcinogenesis_Homo sapiens_hsa052041.14805416
46Taste transduction_Homo sapiens_hsa047421.14646628
47Salivary secretion_Homo sapiens_hsa049701.11577269
48Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.11035835
49Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.10123872
50Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.09813849
51Alzheimers disease_Homo sapiens_hsa050101.08690081
52Long-term potentiation_Homo sapiens_hsa047201.07823258
53Sphingolipid metabolism_Homo sapiens_hsa006001.06919829
54beta-Alanine metabolism_Homo sapiens_hsa004101.04806343
55Parkinsons disease_Homo sapiens_hsa050121.04335454
56Other glycan degradation_Homo sapiens_hsa005111.04208883
57PPAR signaling pathway_Homo sapiens_hsa033201.04138114
58Folate biosynthesis_Homo sapiens_hsa007901.02883471
59Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.02629520
60Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.02132940
61Glycerophospholipid metabolism_Homo sapiens_hsa005641.01915475
62Phenylalanine metabolism_Homo sapiens_hsa003601.01241906
63Complement and coagulation cascades_Homo sapiens_hsa046100.98357323
64Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.95200322
65Insulin secretion_Homo sapiens_hsa049110.94742400
66Renin-angiotensin system_Homo sapiens_hsa046140.94399490
67Retinol metabolism_Homo sapiens_hsa008300.93932773
68Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.92574466
69Prion diseases_Homo sapiens_hsa050200.92244746
70Olfactory transduction_Homo sapiens_hsa047400.91952035
71Tyrosine metabolism_Homo sapiens_hsa003500.89677282
72Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.89527351
73Serotonergic synapse_Homo sapiens_hsa047260.89051071
74Vibrio cholerae infection_Homo sapiens_hsa051100.88218996
75Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.86335748
76Dopaminergic synapse_Homo sapiens_hsa047280.83233814
77Arachidonic acid metabolism_Homo sapiens_hsa005900.81843763
78Biosynthesis of amino acids_Homo sapiens_hsa012300.81730734
79Glycerolipid metabolism_Homo sapiens_hsa005610.81254805
80Carbon metabolism_Homo sapiens_hsa012000.80925248
81Lysosome_Homo sapiens_hsa041420.79640413
82Pentose and glucuronate interconversions_Homo sapiens_hsa000400.77865506
83Fat digestion and absorption_Homo sapiens_hsa049750.77478883
84Long-term depression_Homo sapiens_hsa047300.76450280
85Maturity onset diabetes of the young_Homo sapiens_hsa049500.74939559
86Arginine and proline metabolism_Homo sapiens_hsa003300.74535082
87Renin secretion_Homo sapiens_hsa049240.74187158
88Calcium signaling pathway_Homo sapiens_hsa040200.70517762
89Linoleic acid metabolism_Homo sapiens_hsa005910.70089910
90Cardiac muscle contraction_Homo sapiens_hsa042600.69738807
91Huntingtons disease_Homo sapiens_hsa050160.68203851
92Drug metabolism - other enzymes_Homo sapiens_hsa009830.67858006
93Ether lipid metabolism_Homo sapiens_hsa005650.65544461
94Cocaine addiction_Homo sapiens_hsa050300.62365866
95alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.61598111
96Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.60877004
97Metabolic pathways_Homo sapiens_hsa011000.60441498
98Glycosaminoglycan degradation_Homo sapiens_hsa005310.60200667
99Aldosterone synthesis and secretion_Homo sapiens_hsa049250.60039163
100Mineral absorption_Homo sapiens_hsa049780.58861757
101Cyanoamino acid metabolism_Homo sapiens_hsa004600.58835144
102Gastric acid secretion_Homo sapiens_hsa049710.57854074
103Sulfur relay system_Homo sapiens_hsa041220.57827533
104Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.57798812
105Regulation of autophagy_Homo sapiens_hsa041400.56430679
106Protein digestion and absorption_Homo sapiens_hsa049740.55489177
107Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.54907385
108Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.54629639
109Phototransduction_Homo sapiens_hsa047440.53089242
110Staphylococcus aureus infection_Homo sapiens_hsa051500.52086107
111Galactose metabolism_Homo sapiens_hsa000520.51216559
112Circadian rhythm_Homo sapiens_hsa047100.48903291
113Fructose and mannose metabolism_Homo sapiens_hsa000510.48107567
114ABC transporters_Homo sapiens_hsa020100.47651076
115Fatty acid biosynthesis_Homo sapiens_hsa000610.47439830
116Caffeine metabolism_Homo sapiens_hsa002320.46799432
117Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.45085442
118Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.42526439
119Thyroid hormone synthesis_Homo sapiens_hsa049180.41148263
120Cholinergic synapse_Homo sapiens_hsa047250.40737419

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