Rank | Gene Set | Z-score |
---|---|---|
1 | Golgi transport vesicle coating (GO:0048200) | 3.96148361 |
2 | COPI coating of Golgi vesicle (GO:0048205) | 3.96148361 |
3 | focal adhesion assembly (GO:0048041) | 3.58386775 |
4 | cell-substrate adherens junction assembly (GO:0007045) | 3.58386775 |
5 | bone trabecula formation (GO:0060346) | 3.48635194 |
6 | maintenance of protein localization in endoplasmic reticulum (GO:0035437) | 3.44187418 |
7 | protein retention in ER lumen (GO:0006621) | 3.43525857 |
8 | planar cell polarity pathway involved in neural tube closure (GO:0090179) | 3.30092291 |
9 | protein heterotrimerization (GO:0070208) | 3.29856335 |
10 | convergent extension (GO:0060026) | 3.28166697 |
11 | cortical actin cytoskeleton organization (GO:0030866) | 3.26621748 |
12 | regulation of establishment of planar polarity involved in neural tube closure (GO:0090178) | 3.19902701 |
13 | positive regulation of histone deacetylation (GO:0031065) | 3.15957275 |
14 | regulation of early endosome to late endosome transport (GO:2000641) | 3.14036738 |
15 | outer ear morphogenesis (GO:0042473) | 3.10538321 |
16 | hippo signaling (GO:0035329) | 3.10183088 |
17 | regulation of cellular response to vascular endothelial growth factor stimulus (GO:1902547) | 3.06138019 |
18 | mesenchymal to epithelial transition involved in metanephros morphogenesis (GO:0003337) | 3.05724604 |
19 | semaphorin-plexin signaling pathway (GO:0071526) | 3.04263829 |
20 | polarized epithelial cell differentiation (GO:0030859) | 3.02095777 |
21 | cytoskeletal anchoring at plasma membrane (GO:0007016) | 2.97897885 |
22 | insulin-like growth factor receptor signaling pathway (GO:0048009) | 2.96757901 |
23 | nuclear pore complex assembly (GO:0051292) | 2.96592761 |
24 | lateral sprouting from an epithelium (GO:0060601) | 2.95335143 |
25 | hemidesmosome assembly (GO:0031581) | 2.94132373 |
26 | cytoplasmic mRNA processing body assembly (GO:0033962) | 2.93636770 |
27 | vascular endothelial growth factor signaling pathway (GO:0038084) | 2.92254926 |
28 | glomerular filtration (GO:0003094) | 2.88997280 |
29 | barbed-end actin filament capping (GO:0051016) | 2.88475016 |
30 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 2.88134253 |
31 | cell migration involved in heart development (GO:0060973) | 2.87229960 |
32 | cell migration involved in sprouting angiogenesis (GO:0002042) | 2.86620135 |
33 | DNA unwinding involved in DNA replication (GO:0006268) | 2.84757775 |
34 | regulation of glucose import in response to insulin stimulus (GO:2001273) | 2.84031421 |
35 | cortical cytoskeleton organization (GO:0030865) | 2.82138129 |
36 | collagen metabolic process (GO:0032963) | 2.81593451 |
37 | positive regulation of SMAD protein import into nucleus (GO:0060391) | 2.81161396 |
38 | renal filtration (GO:0097205) | 2.81049270 |
39 | collagen fibril organization (GO:0030199) | 2.79240559 |
40 | mitotic chromosome condensation (GO:0007076) | 2.77281950 |
41 | retrograde vesicle-mediated transport, Golgi to ER (GO:0006890) | 2.77224432 |
42 | endothelial cell morphogenesis (GO:0001886) | 2.76758427 |
43 | central nervous system myelination (GO:0022010) | 2.76644109 |
44 | axon ensheathment in central nervous system (GO:0032291) | 2.76644109 |
45 | dichotomous subdivision of an epithelial terminal unit (GO:0060600) | 2.75605740 |
46 | heart morphogenesis (GO:0003007) | 2.72624673 |
47 | endocardial cushion development (GO:0003197) | 2.71176322 |
48 | regulation of NFAT protein import into nucleus (GO:0051532) | 2.70609045 |
49 | regulation of vascular endothelial growth factor signaling pathway (GO:1900746) | 2.70065561 |
50 | notochord development (GO:0030903) | 2.68747763 |
51 | axon ensheathment (GO:0008366) | 2.68700953 |
52 | ensheathment of neurons (GO:0007272) | 2.68700953 |
53 | multicellular organismal macromolecule metabolic process (GO:0044259) | 2.67857749 |
54 | regulation of nucleobase-containing compound transport (GO:0032239) | 2.67544852 |
55 | embryonic retina morphogenesis in camera-type eye (GO:0060059) | 2.66750774 |
56 | protein localization to endosome (GO:0036010) | 2.65479138 |
57 | regulation of SMAD protein import into nucleus (GO:0060390) | 2.65305187 |
58 | paraxial mesoderm development (GO:0048339) | 2.65221192 |
59 | adherens junction assembly (GO:0034333) | 2.64828877 |
60 | peptidyl-proline hydroxylation (GO:0019511) | 2.64365609 |
61 | cell adhesion mediated by integrin (GO:0033627) | 2.63868192 |
62 | collagen catabolic process (GO:0030574) | 2.63785773 |
63 | glucocorticoid receptor signaling pathway (GO:0042921) | 2.63527053 |
64 | endodermal cell differentiation (GO:0035987) | 2.62238468 |
65 | craniofacial suture morphogenesis (GO:0097094) | 2.62223545 |
66 | cellular protein complex localization (GO:0034629) | 2.60531392 |
67 | kidney mesenchyme development (GO:0072074) | 2.60186951 |
68 | response to laminar fluid shear stress (GO:0034616) | 2.59969368 |
69 | myelin maintenance (GO:0043217) | 2.59500826 |
70 | germ cell migration (GO:0008354) | 2.58813112 |
71 | myelination (GO:0042552) | 2.58467575 |
72 | vascular endothelial growth factor receptor signaling pathway (GO:0048010) | 2.58432098 |
73 | Wnt signaling pathway, planar cell polarity pathway (GO:0060071) | 2.57472980 |
74 | blood vessel endothelial cell migration (GO:0043534) | 2.56496690 |
75 | atrioventricular valve morphogenesis (GO:0003181) | 2.56153634 |
76 | negative regulation of cell size (GO:0045792) | 2.55024863 |
77 | cardiac myofibril assembly (GO:0055003) | 2.54487528 |
78 | regulation of establishment of planar polarity (GO:0090175) | 2.54427983 |
79 | response to fluid shear stress (GO:0034405) | 2.52964021 |
80 | basement membrane organization (GO:0071711) | 2.52873734 |
81 | endothelial cell chemotaxis (GO:0035767) | 2.51836696 |
82 | positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S tr | 2.51135726 |
83 | cellular response to vascular endothelial growth factor stimulus (GO:0035924) | 2.49993593 |
84 | multicellular organismal metabolic process (GO:0044236) | 2.49279871 |
85 | apoptotic process involved in morphogenesis (GO:0060561) | 2.48565687 |
86 | anatomical structure regression (GO:0060033) | 2.48499299 |
87 | retina vasculature morphogenesis in camera-type eye (GO:0061299) | 2.47732438 |
88 | gastrulation with mouth forming second (GO:0001702) | 2.47062338 |
89 | extracellular matrix disassembly (GO:0022617) | 2.46914133 |
90 | regulation of translational fidelity (GO:0006450) | 2.46425701 |
91 | negative regulation of catenin import into nucleus (GO:0035414) | 2.46317557 |
92 | lens fiber cell development (GO:0070307) | 2.46274335 |
93 | stress fiber assembly (GO:0043149) | 2.45962148 |
94 | peripheral nervous system axon ensheathment (GO:0032292) | 2.45777246 |
95 | myelination in peripheral nervous system (GO:0022011) | 2.45777246 |
96 | vesicle coating (GO:0006901) | 2.44634343 |
97 | axis elongation (GO:0003401) | 2.44584320 |
98 | cell-substrate junction assembly (GO:0007044) | 2.44192304 |
99 | chondrocyte proliferation (GO:0035988) | 2.43909879 |
100 | mesodermal cell differentiation (GO:0048333) | 2.43722614 |
101 | camera-type eye morphogenesis (GO:0048593) | 2.43343411 |
102 | regulation of mammary gland epithelial cell proliferation (GO:0033599) | 2.42738520 |
103 | multicellular organismal catabolic process (GO:0044243) | 2.40290258 |
104 | head development (GO:0060322) | 2.38874375 |
105 | protein complex localization (GO:0031503) | 2.38758399 |
106 | activation of signaling protein activity involved in unfolded protein response (GO:0006987) | 2.38676500 |
107 | establishment of epithelial cell polarity (GO:0090162) | 2.37711950 |
108 | negative regulation of chondrocyte differentiation (GO:0032331) | 2.37224292 |
109 | nuclear pore organization (GO:0006999) | 2.35407207 |
110 | face morphogenesis (GO:0060325) | 2.34566641 |
111 | positive regulation of blood vessel endothelial cell migration (GO:0043536) | 2.34458298 |
112 | eye morphogenesis (GO:0048592) | 2.34207019 |
113 | heterochromatin organization (GO:0070828) | 2.33976632 |
114 | positive regulation of epithelial to mesenchymal transition (GO:0010718) | 2.33937021 |
115 | cranial suture morphogenesis (GO:0060363) | 2.33646563 |
116 | regulation of RNA export from nucleus (GO:0046831) | 2.33627496 |
117 | RNA stabilization (GO:0043489) | 2.33534348 |
118 | mRNA stabilization (GO:0048255) | 2.33534348 |
119 | neuron projection extension involved in neuron projection guidance (GO:1902284) | 2.33408034 |
120 | axon extension involved in axon guidance (GO:0048846) | 2.33408034 |
121 | proline biosynthetic process (GO:0006561) | 2.32599437 |
122 | positive regulation of osteoblast proliferation (GO:0033690) | 2.32161595 |
123 | positive regulation of nuclease activity (GO:0032075) | 2.32136380 |
124 | establishment or maintenance of apical/basal cell polarity (GO:0035088) | 2.32109936 |
125 | establishment or maintenance of bipolar cell polarity (GO:0061245) | 2.32109936 |
126 | protein hydroxylation (GO:0018126) | 2.32057005 |
127 | pre-miRNA processing (GO:0031054) | 2.31851575 |
128 | positive regulation of gene expression, epigenetic (GO:0045815) | 2.31623436 |
129 | metanephric mesenchyme development (GO:0072075) | 2.31553451 |
130 | regulation of branching involved in prostate gland morphogenesis (GO:0060687) | 2.30106975 |
131 | maternal placenta development (GO:0001893) | 2.30026276 |
132 | establishment of mitotic spindle orientation (GO:0000132) | 2.29285770 |
133 | extracellular fibril organization (GO:0043206) | 2.28805432 |
134 | embryonic eye morphogenesis (GO:0048048) | 2.28782996 |
135 | pathway-restricted SMAD protein phosphorylation (GO:0060389) | 2.28153383 |
136 | nucleosome disassembly (GO:0006337) | 2.27902757 |
137 | protein-DNA complex disassembly (GO:0032986) | 2.27902757 |
138 | non-canonical Wnt signaling pathway (GO:0035567) | 2.27821683 |
139 | establishment of apical/basal cell polarity (GO:0035089) | 2.27817114 |
140 | cochlea morphogenesis (GO:0090103) | 2.27790425 |
141 | apoptotic cell clearance (GO:0043277) | 2.27372498 |
142 | somatic stem cell division (GO:0048103) | 2.26705492 |
143 | neural tube development (GO:0021915) | 2.26367559 |
144 | establishment of mitotic spindle localization (GO:0040001) | 2.25760070 |
145 | regulation of transcription from RNA polymerase II promoter in response to oxidative stress (GO:0043 | 2.25758682 |
146 | establishment or maintenance of epithelial cell apical/basal polarity (GO:0045197) | 2.25579819 |
147 | trabecula formation (GO:0060343) | 2.25182495 |
148 | skin morphogenesis (GO:0043589) | 2.24718392 |
149 | epithelial cell-cell adhesion (GO:0090136) | 2.24392244 |
150 | cell proliferation involved in metanephros development (GO:0072203) | 2.24035791 |
151 | branching involved in salivary gland morphogenesis (GO:0060445) | 2.22456562 |
152 | substrate adhesion-dependent cell spreading (GO:0034446) | 2.22142694 |
153 | extracellular matrix assembly (GO:0085029) | 2.21298955 |
154 | glomerular basement membrane development (GO:0032836) | 2.21247873 |
155 | renal system development (GO:0072001) | 2.21100119 |
156 | regulation of hippo signaling (GO:0035330) | 2.21054767 |
157 | dorsal/ventral axis specification (GO:0009950) | 2.20186317 |
158 | regulation of extracellular matrix disassembly (GO:0010715) | 2.20125835 |
159 | negative regulation of fatty acid transport (GO:2000192) | 2.19337944 |
160 | ruffle organization (GO:0031529) | 2.18877856 |
161 | hindlimb morphogenesis (GO:0035137) | 2.18610849 |
Rank | Gene Set | Z-score |
---|---|---|
1 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 3.69414404 |
2 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 3.56476472 |
3 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 3.36491826 |
4 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 3.06721381 |
5 | EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse | 3.02341581 |
6 | KDM2B_26808549_Chip-Seq_DND41_Human | 2.48335712 |
7 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 2.44895615 |
8 | MYC_22102868_ChIP-Seq_BL_Human | 2.40417469 |
9 | ELK3_25401928_ChIP-Seq_HUVEC_Human | 2.38555227 |
10 | WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse | 2.37827048 |
11 | E2F7_22180533_ChIP-Seq_HELA_Human | 2.35657139 |
12 | * EGR1_19374776_ChIP-ChIP_THP-1_Human | 2.32871705 |
13 | * VDR_21846776_ChIP-Seq_THP-1_Human | 2.29958033 |
14 | TCF7_22412390_ChIP-Seq_EML_Mouse | 2.24232164 |
15 | TRIM28_21343339_ChIP-Seq_HEK293_Human | 2.20784227 |
16 | KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 2.16965881 |
17 | RUNX2_24764292_ChIP-Seq_MC3T3_Mouse | 2.14475691 |
18 | ZNF263_19887448_ChIP-Seq_K562_Human | 2.09262223 |
19 | KDM2B_26808549_Chip-Seq_HPB-ALL_Human | 2.04130796 |
20 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 2.02925015 |
21 | ZFP281_27345836_Chip-Seq_ESCs_Mouse | 2.00672625 |
22 | NFIB_24661679_ChIP-Seq_LUNG_Mouse | 1.99819341 |
23 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 1.97826962 |
24 | DMRT1_23473982_ChIP-Seq_TESTES_Mouse | 1.92377286 |
25 | P300_27058665_Chip-Seq_ZR-75-30cells_Human | 1.91903816 |
26 | SMAD3_22036565_ChIP-Seq_ESCs_Mouse | 1.89520779 |
27 | KDM2B_26808549_Chip-Seq_JURKAT_Human | 1.86940903 |
28 | WT1_19549856_ChIP-ChIP_CCG9911_Human | 1.85501418 |
29 | ZFP281_18757296_ChIP-ChIP_E14_Mouse | 1.77899509 |
30 | * TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 1.76859173 |
31 | KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.76755011 |
32 | POU5F1_18700969_ChIP-ChIP_MESCs_Mouse | 1.75962502 |
33 | CLOCK_20551151_ChIP-Seq_293T_Human | 1.72414381 |
34 | EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.69563751 |
35 | ISL1_27105846_Chip-Seq_CPCs_Mouse | 1.69465106 |
36 | TCF3_18467660_ChIP-ChIP_MESCs_Mouse | 1.66391405 |
37 | * KDM2B_26808549_Chip-Seq_K562_Human | 1.64305132 |
38 | RARG_19884340_ChIP-ChIP_MEFs_Mouse | 1.62446015 |
39 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 1.56574182 |
40 | TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse | 1.54802728 |
41 | * ESR1_22446102_ChIP-Seq_UTERUS_Mouse | 1.54486603 |
42 | SOX9_24532713_ChIP-Seq_HFSC_Mouse | 1.54274813 |
43 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 1.54025527 |
44 | * VDR_24763502_ChIP-Seq_THP-1_Human | 1.52562009 |
45 | RACK7_27058665_Chip-Seq_MCF-7_Human | 1.51152970 |
46 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 1.47895077 |
47 | * TP53_22127205_ChIP-Seq_IMR90_Human | 1.47861932 |
48 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 1.47755688 |
49 | FOXO3_23340844_ChIP-Seq_DLD1_Human | 1.46782706 |
50 | CCND1_20090754_ChIP-ChIP_RETINA_Mouse | 1.44478096 |
51 | * TBX20_22080862_ChIP-Seq_HEART_Mouse | 1.44428790 |
52 | * TBX20_22328084_ChIP-Seq_HEART_Mouse | 1.44428790 |
53 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 1.43286456 |
54 | TFAP2C_20629094_ChIP-Seq_MCF-7_Human | 1.43208935 |
55 | KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.40748762 |
56 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 1.40026896 |
57 | KLF4_18358816_ChIP-ChIP_MESCs_Mouse | 1.38249968 |
58 | SCL_19346495_ChIP-Seq_HPC-7_Human | 1.38133646 |
59 | ZFP281_18358816_ChIP-ChIP_MESCs_Mouse | 1.37201625 |
60 | ERG_21242973_ChIP-ChIP_JURKAT_Human | 1.36952310 |
61 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 1.36544748 |
62 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.36073826 |
63 | FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human | 1.35858756 |
64 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 1.35055512 |
65 | HIF1A_21447827_ChIP-Seq_MCF-7_Human | 1.34104608 |
66 | EP300_21415370_ChIP-Seq_HL-1_Mouse | 1.33899902 |
67 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 1.33693719 |
68 | LXR_22292898_ChIP-Seq_THP-1_Human | 1.30946211 |
69 | CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat | 1.30145346 |
70 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 1.30014479 |
71 | SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse | 1.29477595 |
72 | DACH1_20351289_ChIP-Seq_MDA-MB-231_Human | 1.28580717 |
73 | * WT1_25993318_ChIP-Seq_PODOCYTE_Human | 1.28412142 |
74 | UTX_26944678_Chip-Seq_JUKART_Human | 1.27650582 |
75 | MAF_26560356_Chip-Seq_TH1_Human | 1.27647209 |
76 | HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse | 1.27498281 |
77 | UBF1/2_26484160_Chip-Seq_HMECs_Human | 1.26394863 |
78 | * ATF3_27146783_Chip-Seq_COLON_Human | 1.26097236 |
79 | FOXP2_23625967_ChIP-Seq_PFSK-1_AND_SK-N-MC_Human | 1.25907165 |
80 | SALL4_18804426_ChIP-ChIP_MESCs_Mouse | 1.24788159 |
81 | * KLF4_18555785_ChIP-Seq_MESCs_Mouse | 1.24369079 |
82 | ZNF652_21678463_ChIP-ChIP_ZR75-1_Human | 1.23100989 |
83 | ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.22683350 |
84 | * CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse | 1.22127715 |
85 | CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse | 1.21029523 |
86 | NKX2-5_21415370_ChIP-Seq_HL-1_Mouse | 1.20783697 |
87 | * NCOR1_26117541_ChIP-Seq_K562_Human | 1.20580681 |
88 | * RUNX1_27514584_Chip-Seq_MCF-7_Human | 1.20360078 |
89 | NANOG_18700969_ChIP-ChIP_MESCs_Mouse | 1.19949015 |
90 | CREB1_26743006_Chip-Seq_LNCaP-abl_Human | 1.18272556 |
91 | * BRD4_25478319_ChIP-Seq_HGPS_Human | 1.16859844 |
92 | KLF5_18264089_ChIP-ChIP_MESCs_Mouse | 1.16630788 |
93 | KLF4_18264089_ChIP-ChIP_MESCs_Mouse | 1.16630788 |
94 | KLF2_18264089_ChIP-ChIP_MESCs_Mouse | 1.16630788 |
95 | SPI1_23127762_ChIP-Seq_K562_Human | 1.15732730 |
96 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 1.14898485 |
97 | TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.14115019 |
98 | PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse | 1.11969806 |
99 | GATA1_19941826_ChIP-Seq_K562_Human | 1.11691158 |
100 | PPAR_26484153_Chip-Seq_NCI-H1993_Human | 1.11638798 |
101 | NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human | 1.10017545 |
102 | * ZFX_18555785_ChIP-Seq_MESCs_Mouse | 1.09268777 |
103 | ESR1_15608294_ChIP-ChIP_MCF-7_Human | 1.08783612 |
104 | UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human | 1.07392543 |
105 | TP53_16413492_ChIP-PET_HCT116_Human | 1.07223638 |
106 | NR0B1_18358816_ChIP-ChIP_MESCs_Mouse | 1.06188276 |
107 | * CREB1_26743006_Chip-Seq_LNCaP_Human | 1.05277251 |
108 | * TP53_23651856_ChIP-Seq_MEFs_Mouse | 1.04599617 |
109 | CTCF_27219007_Chip-Seq_ERYTHROID_Human | 1.04399820 |
110 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 1.03484765 |
111 | CTNNB1_20460455_ChIP-Seq_HCT116_Human | 1.01413949 |
112 | TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse | 1.01038357 |
113 | * TET1_21490601_ChIP-Seq_MESCs_Mouse | 0.97960357 |
114 | ZIC3_20872845_ChIP-ChIP_MESCs_Mouse | 0.97891358 |
115 | DROSHA_22980978_ChIP-Seq_HELA_Human | 0.97239893 |
116 | SMAD4_19686287_ChIP-ChIP_HaCaT_Human | 0.96774013 |
117 | ZNF217_24962896_ChIP-Seq_MCF-7_Human | 0.96760347 |
118 | TET1_21451524_ChIP-Seq_MESCs_Mouse | 0.96450363 |
119 | RING1B_27294783_Chip-Seq_NPCs_Mouse | 0.95729459 |
120 | HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse | 0.95455233 |
121 | NANOG_21062744_ChIP-ChIP_HESCs_Human | 0.95233730 |
122 | BRD4_27068464_Chip-Seq_AML-cells_Mouse | 0.95081043 |
123 | SA1_27219007_Chip-Seq_ERYTHROID_Human | 0.94782873 |
124 | * SMAD3_18955504_ChIP-ChIP_HaCaT_Human | 0.94090765 |
125 | * SMAD2_18955504_ChIP-ChIP_HaCaT_Human | 0.94090765 |
126 | * PRDM5_23873026_ChIP-Seq_MEFs_Mouse | 0.93728088 |
127 | CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 0.93351096 |
128 | SMC1_22415368_ChIP-Seq_MEFs_Mouse | 0.93348352 |
129 | KLF5_25053715_ChIP-Seq_YYC3_Human | 0.93329025 |
130 | AR_21909140_ChIP-Seq_LNCAP_Human | 0.93111965 |
131 | * EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human | 0.93106332 |
132 | SMAD1_18555785_ChIP-Seq_MESCs_Mouse | 0.92823513 |
133 | ESR1_20079471_ChIP-ChIP_T-47D_Human | 0.90127984 |
134 | * NANOG_18347094_ChIP-ChIP_MESCs_Mouse | 0.89754879 |
135 | * OLIG2_26023283_ChIP-Seq_AINV15_Mouse | 0.89699554 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0008438_abnormal_cutaneous_collagen | 4.49084466 |
2 | MP0003705_abnormal_hypodermis_morpholog | 3.11328147 |
3 | MP0005623_abnormal_meninges_morphology | 2.88312037 |
4 | MP0000733_abnormal_muscle_development | 2.42015971 |
5 | MP0010030_abnormal_orbit_morphology | 2.32041985 |
6 | MP0002877_abnormal_melanocyte_morpholog | 2.21030348 |
7 | MP0004272_abnormal_basement_membrane | 2.16379434 |
8 | MP0003279_aneurysm | 2.07967532 |
9 | MP0004858_abnormal_nervous_system | 2.07310921 |
10 | MP0005275_abnormal_skin_tensile | 2.02451744 |
11 | MP0005503_abnormal_tendon_morphology | 1.97231391 |
12 | MP0000537_abnormal_urethra_morphology | 1.95218242 |
13 | MP0005076_abnormal_cell_differentiation | 1.94970275 |
14 | * MP0003385_abnormal_body_wall | 1.93399306 |
15 | MP0003566_abnormal_cell_adhesion | 1.92651834 |
16 | MP0010352_gastrointestinal_tract_polyps | 1.91011848 |
17 | MP0006054_spinal_hemorrhage | 1.80116276 |
18 | MP0001958_emphysema | 1.71231664 |
19 | MP0000428_abnormal_craniofacial_morphol | 1.70642131 |
20 | MP0005409_darkened_coat_color | 1.69585998 |
21 | MP0003300_gastrointestinal_ulcer | 1.68307744 |
22 | MP0009053_abnormal_anal_canal | 1.64905709 |
23 | MP0003115_abnormal_respiratory_system | 1.61395558 |
24 | MP0003091_abnormal_cell_migration | 1.57836252 |
25 | MP0001849_ear_inflammation | 1.57384016 |
26 | MP0003937_abnormal_limbs/digits/tail_de | 1.54544600 |
27 | MP0000767_abnormal_smooth_muscle | 1.54153942 |
28 | MP0009250_abnormal_appendicular_skeleto | 1.54133241 |
29 | MP0003941_abnormal_skin_development | 1.47588560 |
30 | * MP0009278_abnormal_bone_marrow | 1.46157917 |
31 | MP0000383_abnormal_hair_follicle | 1.45399193 |
32 | MP0003935_abnormal_craniofacial_develop | 1.42971375 |
33 | MP0010678_abnormal_skin_adnexa | 1.42077548 |
34 | MP0009384_cardiac_valve_regurgitation | 1.40902815 |
35 | MP0000534_abnormal_ureter_morphology | 1.40404757 |
36 | MP0005508_abnormal_skeleton_morphology | 1.39832111 |
37 | MP0002932_abnormal_joint_morphology | 1.39786673 |
38 | MP0003950_abnormal_plasma_membrane | 1.37258461 |
39 | MP0002925_abnormal_cardiovascular_devel | 1.35962391 |
40 | MP0005023_abnormal_wound_healing | 1.35778448 |
41 | MP0004185_abnormal_adipocyte_glucose | 1.34946886 |
42 | MP0004197_abnormal_fetal_growth/weight/ | 1.34759914 |
43 | MP0005257_abnormal_intraocular_pressure | 1.34650156 |
44 | MP0004134_abnormal_chest_morphology | 1.33248736 |
45 | MP0002249_abnormal_larynx_morphology | 1.31114576 |
46 | MP0000678_abnormal_parathyroid_gland | 1.26095283 |
47 | MP0003942_abnormal_urinary_system | 1.23827594 |
48 | MP0000432_abnormal_head_morphology | 1.23544557 |
49 | MP0002697_abnormal_eye_size | 1.18892961 |
50 | * MP0010630_abnormal_cardiac_muscle | 1.17631756 |
51 | * MP0002092_abnormal_eye_morphology | 1.16129283 |
52 | MP0009672_abnormal_birth_weight | 1.15820726 |
53 | MP0004808_abnormal_hematopoietic_stem | 1.15810061 |
54 | MP0001915_intracranial_hemorrhage | 1.15513045 |
55 | * MP0002085_abnormal_embryonic_tissue | 1.15429034 |
56 | MP0010368_abnormal_lymphatic_system | 1.14642800 |
57 | MP0001348_abnormal_lacrimal_gland | 1.13705165 |
58 | MP0002084_abnormal_developmental_patter | 1.12952178 |
59 | MP0004233_abnormal_muscle_weight | 1.12688297 |
60 | MP0003755_abnormal_palate_morphology | 1.11897614 |
61 | MP0002060_abnormal_skin_morphology | 1.11170793 |
62 | MP0002108_abnormal_muscle_morphology | 1.10900408 |
63 | MP0000049_abnormal_middle_ear | 1.10483565 |
64 | MP0002396_abnormal_hematopoietic_system | 1.09485721 |
65 | MP0000569_abnormal_digit_pigmentation | 1.08442074 |
66 | MP0000003_abnormal_adipose_tissue | 1.08026139 |
67 | MP0000759_abnormal_skeletal_muscle | 1.06652010 |
68 | MP0001614_abnormal_blood_vessel | 1.06627775 |
69 | MP0005375_adipose_tissue_phenotype | 1.06288168 |
70 | MP0001299_abnormal_eye_distance/ | 1.06192756 |
71 | MP0006138_congestive_heart_failure | 1.06140259 |
72 | MP0003984_embryonic_growth_retardation | 1.04933696 |
73 | MP0002088_abnormal_embryonic_growth/wei | 1.04090152 |
74 | MP0002111_abnormal_tail_morphology | 1.03426782 |
75 | MP0002282_abnormal_trachea_morphology | 1.02605406 |
76 | * MP0002116_abnormal_craniofacial_bone | 1.02344287 |
77 | MP0003303_peritoneal_inflammation | 1.01811491 |
78 | MP0003122_maternal_imprinting | 1.01590475 |
79 | MP0000762_abnormal_tongue_morphology | 1.00919235 |
80 | MP0001293_anophthalmia | 1.00314428 |
81 | MP0003045_fibrosis | 1.00219648 |
82 | MP0000566_synostosis | 0.99832238 |
83 | MP0001672_abnormal_embryogenesis/_devel | 0.99628668 |
84 | MP0005380_embryogenesis_phenotype | 0.99628668 |
85 | MP0003121_genomic_imprinting | 0.97720854 |
86 | * MP0002128_abnormal_blood_circulation | 0.97568913 |
87 | MP0000013_abnormal_adipose_tissue | 0.97418541 |
88 | MP0000920_abnormal_myelination | 0.96750657 |
89 | MP0005666_abnormal_adipose_tissue | 0.96409813 |
90 | MP0008932_abnormal_embryonic_tissue | 0.94883771 |
91 | MP0001879_abnormal_lymphatic_vessel | 0.94869415 |
92 | MP0003111_abnormal_nucleus_morphology | 0.94024587 |
93 | * MP0004087_abnormal_muscle_fiber | 0.93926376 |
94 | MP0005451_abnormal_body_composition | 0.92904408 |
95 | MP0003453_abnormal_keratinocyte_physiol | 0.91951855 |
96 | * MP0000266_abnormal_heart_morphology | 0.91908254 |
97 | MP0002896_abnormal_bone_mineralization | 0.90514889 |
98 | MP0002086_abnormal_extraembryonic_tissu | 0.90362529 |
99 | MP0002938_white_spotting | 0.89985001 |
100 | MP0004084_abnormal_cardiac_muscle | 0.89868814 |
101 | MP0003283_abnormal_digestive_organ | 0.89826258 |
102 | MP0002089_abnormal_postnatal_growth/wei | 0.88913965 |
103 | MP0001243_abnormal_dermal_layer | 0.88289125 |
104 | MP0009703_decreased_birth_body | 0.88241386 |
105 | MP0003938_abnormal_ear_development | 0.88146119 |
106 | MP0002796_impaired_skin_barrier | 0.87578763 |
107 | MP0002109_abnormal_limb_morphology | 0.87293260 |
108 | MP0000751_myopathy | 0.86825303 |
109 | MP0002114_abnormal_axial_skeleton | 0.86790758 |
110 | MP0010234_abnormal_vibrissa_follicle | 0.86648655 |
111 | * MP0001784_abnormal_fluid_regulation | 0.85027030 |
112 | MP0002233_abnormal_nose_morphology | 0.84839321 |
113 | MP0000747_muscle_weakness | 0.84501596 |
114 | MP0001730_embryonic_growth_arrest | 0.84394518 |
115 | MP0009780_abnormal_chondrocyte_physiolo | 0.83650492 |
116 | MP0000579_abnormal_nail_morphology | 0.83605724 |
117 | * MP0002080_prenatal_lethality | 0.82713382 |
118 | MP0005621_abnormal_cell_physiology | 0.82682316 |
119 | MP0000350_abnormal_cell_proliferation | 0.82393210 |
120 | MP0002113_abnormal_skeleton_development | 0.80920507 |
121 | MP0000163_abnormal_cartilage_morphology | 0.80555530 |
122 | MP0001697_abnormal_embryo_size | 0.80494017 |
123 | MP0004957_abnormal_blastocyst_morpholog | 0.77999932 |
124 | MP0005501_abnormal_skin_physiology | 0.77781996 |
125 | MP0001542_abnormal_bone_strength | 0.77613409 |
126 | MP0005171_absent_coat_pigmentation | 0.76536639 |
127 | MP0005197_abnormal_uvea_morphology | 0.75347223 |
128 | MP0009840_abnormal_foam_cell | 0.75222585 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Premature rupture of membranes (HP:0001788) | 4.23760094 |
2 | Shallow orbits (HP:0000586) | 4.21133455 |
3 | Protrusio acetabuli (HP:0003179) | 4.07970234 |
4 | Cerebral aneurysm (HP:0004944) | 4.01223152 |
5 | Short 4th metacarpal (HP:0010044) | 3.62400228 |
6 | Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042) | 3.62400228 |
7 | Broad metatarsal (HP:0001783) | 3.46895866 |
8 | Aortic dissection (HP:0002647) | 3.28727785 |
9 | Ankle contracture (HP:0006466) | 3.17286215 |
10 | Bladder diverticulum (HP:0000015) | 3.12135629 |
11 | Abnormality of the 4th metacarpal (HP:0010012) | 2.98653214 |
12 | Aortic aneurysm (HP:0004942) | 2.93746358 |
13 | Hyperacusis (HP:0010780) | 2.83684493 |
14 | Ulnar bowing (HP:0003031) | 2.82386560 |
15 | Mitral valve prolapse (HP:0001634) | 2.79238378 |
16 | Atrophic scars (HP:0001075) | 2.76287895 |
17 | Cervical subluxation (HP:0003308) | 2.75771334 |
18 | Neonatal short-limb short stature (HP:0008921) | 2.72066671 |
19 | Renal duplication (HP:0000075) | 2.70609374 |
20 | Disproportionate tall stature (HP:0001519) | 2.60750395 |
21 | Biconcave vertebral bodies (HP:0004586) | 2.57075909 |
22 | Vertebral compression fractures (HP:0002953) | 2.51740043 |
23 | Overriding aorta (HP:0002623) | 2.48888917 |
24 | Increased variability in muscle fiber diameter (HP:0003557) | 2.47064889 |
25 | Deviation of the hallux (HP:0010051) | 2.43819799 |
26 | Soft skin (HP:0000977) | 2.43545570 |
27 | Scapular winging (HP:0003691) | 2.42085826 |
28 | Hallux valgus (HP:0001822) | 2.39023056 |
29 | Buphthalmos (HP:0000557) | 2.33609316 |
30 | Asymmetry of the thorax (HP:0001555) | 2.33088672 |
31 | Dilatation of the ascending aorta (HP:0005111) | 2.32514544 |
32 | Bowel diverticulosis (HP:0005222) | 2.32169592 |
33 | Mildly elevated creatine phosphokinase (HP:0008180) | 2.30704175 |
34 | Flat cornea (HP:0007720) | 2.26664697 |
35 | Obstructive sleep apnea (HP:0002870) | 2.26526608 |
36 | Coronal craniosynostosis (HP:0004440) | 2.21654214 |
37 | Arnold-Chiari malformation (HP:0002308) | 2.20512853 |
38 | Renovascular hypertension (HP:0100817) | 2.19715523 |
39 | Broad face (HP:0000283) | 2.18721958 |
40 | Blue sclerae (HP:0000592) | 2.18294170 |
41 | Fragile skin (HP:0001030) | 2.15975409 |
42 | Arterial tortuosity (HP:0005116) | 2.14862311 |
43 | Abnormality of skeletal muscle fiber size (HP:0012084) | 2.12288083 |
44 | Distal upper limb amyotrophy (HP:0007149) | 2.11245065 |
45 | Upper limb amyotrophy (HP:0009129) | 2.11245065 |
46 | Ankyloglossia (HP:0010296) | 2.10535786 |
47 | Supernumerary ribs (HP:0005815) | 2.10217008 |
48 | Genu recurvatum (HP:0002816) | 2.08232020 |
49 | Breech presentation (HP:0001623) | 2.06223917 |
50 | Vascular tortuosity (HP:0004948) | 2.05541880 |
51 | Increased connective tissue (HP:0009025) | 2.04749621 |
52 | Distal lower limb amyotrophy (HP:0008944) | 2.04627879 |
53 | Elfin facies (HP:0004428) | 2.03749163 |
54 | Overgrowth (HP:0001548) | 2.03410749 |
55 | Natal tooth (HP:0000695) | 2.03286767 |
56 | Type 1 muscle fiber predominance (HP:0003803) | 2.03122548 |
57 | Premature skin wrinkling (HP:0100678) | 2.01520747 |
58 | Abnormality of the acetabulum (HP:0003170) | 2.00428022 |
59 | Abnormality of the calcaneus (HP:0008364) | 1.98939271 |
60 | Thin ribs (HP:0000883) | 1.98778267 |
61 | Macroorchidism (HP:0000053) | 1.96270849 |
62 | Abnormality of the distal phalanx of the thumb (HP:0009617) | 1.96214605 |
63 | Elbow flexion contracture (HP:0002987) | 1.96196478 |
64 | Peritonitis (HP:0002586) | 1.95981984 |
65 | Syringomyelia (HP:0003396) | 1.95412465 |
66 | Spinal cord lesions (HP:0100561) | 1.95412465 |
67 | Mitral regurgitation (HP:0001653) | 1.95299872 |
68 | Broad thumb (HP:0011304) | 1.94747385 |
69 | Achilles tendon contracture (HP:0001771) | 1.94490877 |
70 | Trigonocephaly (HP:0000243) | 1.94077726 |
71 | Increased density of long bones (HP:0006392) | 1.91843630 |
72 | Abnormality of the parietal bone (HP:0002696) | 1.91685275 |
73 | Aneurysm (HP:0002617) | 1.91073401 |
74 | Vertebral arch anomaly (HP:0008438) | 1.90166542 |
75 | Abnormality of oral frenula (HP:0000190) | 1.90023479 |
76 | Long eyelashes (HP:0000527) | 1.88260891 |
77 | Abnormality of the fingertips (HP:0001211) | 1.88091475 |
78 | Bell-shaped thorax (HP:0001591) | 1.87784022 |
79 | Hypoplastic ischia (HP:0003175) | 1.85671678 |
80 | Advanced eruption of teeth (HP:0006288) | 1.85225905 |
81 | Abnormality of the peritoneum (HP:0002585) | 1.84534295 |
82 | Thin bony cortex (HP:0002753) | 1.84371819 |
83 | Patellar dislocation (HP:0002999) | 1.83729373 |
84 | Ectopia lentis (HP:0001083) | 1.83334594 |
85 | Abnormal delivery (HP:0001787) | 1.82228641 |
86 | Increased nuchal translucency (HP:0010880) | 1.81703682 |
87 | Wormian bones (HP:0002645) | 1.81152667 |
88 | Rectal prolapse (HP:0002035) | 1.80949344 |
89 | Flat acetabular roof (HP:0003180) | 1.79954837 |
90 | Supernumerary bones of the axial skeleton (HP:0009144) | 1.79781372 |
91 | Spinal rigidity (HP:0003306) | 1.78761829 |
92 | Bicuspid aortic valve (HP:0001647) | 1.78463857 |
93 | Turricephaly (HP:0000262) | 1.77847596 |
94 | Narrow palate (HP:0000189) | 1.76553600 |
95 | Lower limb amyotrophy (HP:0007210) | 1.76332708 |
96 | Chin dimple (HP:0010751) | 1.76178266 |
97 | Wrist flexion contracture (HP:0001239) | 1.75692817 |
98 | Camptodactyly of toe (HP:0001836) | 1.75577938 |
99 | Wide anterior fontanel (HP:0000260) | 1.75251691 |
100 | Long palpebral fissure (HP:0000637) | 1.74929909 |
101 | Short nail (HP:0001799) | 1.74900749 |
102 | Pseudobulbar signs (HP:0002200) | 1.74506024 |
103 | Hyporeflexia of lower limbs (HP:0002600) | 1.74172082 |
104 | Hypoventilation (HP:0002791) | 1.73368876 |
105 | Arachnodactyly (HP:0001166) | 1.72417230 |
106 | Venous abnormality (HP:0002624) | 1.72024431 |
107 | Joint laxity (HP:0001388) | 1.71647364 |
108 | Broad ribs (HP:0000885) | 1.71321802 |
109 | Nonimmune hydrops fetalis (HP:0001790) | 1.71109589 |
110 | Follicular hyperkeratosis (HP:0007502) | 1.70068574 |
111 | Esophageal atresia (HP:0002032) | 1.69923768 |
112 | Bowing of the arm (HP:0006488) | 1.69795507 |
113 | Bowed forearm bones (HP:0003956) | 1.69795507 |
114 | Osteolytic defects of the phalanges of the hand (HP:0009771) | 1.69728216 |
115 | Osteolytic defects of the hand bones (HP:0009699) | 1.69728216 |
116 | Selective tooth agenesis (HP:0001592) | 1.69629746 |
117 | Muscle fiber splitting (HP:0003555) | 1.68481599 |
118 | Insomnia (HP:0100785) | 1.68423004 |
119 | Lymphangioma (HP:0100764) | 1.68291780 |
120 | Broad toe (HP:0001837) | 1.68160718 |
121 | Abnormality of dentin (HP:0010299) | 1.67569513 |
122 | Broad long bones (HP:0005622) | 1.67187801 |
123 | Hypoplasia of the iris (HP:0007676) | 1.66621148 |
124 | Inguinal hernia (HP:0000023) | 1.66524308 |
125 | Round ear (HP:0100830) | 1.66382623 |
126 | Hand muscle atrophy (HP:0009130) | 1.66185205 |
127 | Aortic regurgitation (HP:0001659) | 1.65732476 |
128 | Midface retrusion (HP:0011800) | 1.65438607 |
129 | Abnormality of the Achilles tendon (HP:0005109) | 1.65205081 |
130 | Protruding ear (HP:0000411) | 1.64708522 |
131 | Slender build (HP:0001533) | 1.64629239 |
132 | Abnormality of the phalanges of the hallux (HP:0010057) | 1.64317832 |
133 | Spondylolisthesis (HP:0003302) | 1.64310032 |
134 | Hyperextensible skin (HP:0000974) | 1.63898184 |
135 | Persistence of primary teeth (HP:0006335) | 1.63500890 |
136 | Hematochezia (HP:0002573) | 1.63405614 |
137 | Urethral obstruction (HP:0000796) | 1.62052629 |
138 | Tibial bowing (HP:0002982) | 1.61944133 |
139 | Limited elbow extension (HP:0001377) | 1.61397378 |
140 | Broad phalanges of the hand (HP:0009768) | 1.60975521 |
141 | Partial duplication of the phalanx of hand (HP:0009999) | 1.59379948 |
142 | Broad hallux (HP:0010055) | 1.57888013 |
Rank | Gene Set | Z-score |
---|---|---|
1 | EEF2K | 3.58982267 |
2 | MAP3K10 | 3.45542667 |
3 | TRIB3 | 3.34381440 |
4 | PKN2 | 3.11166932 |
5 | ICK | 3.08166601 |
6 | SMG1 | 3.02820260 |
7 | TTN | 2.94601339 |
8 | CDK12 | 2.71858446 |
9 | EPHB1 | 2.51641573 |
10 | NTRK1 | 2.43252964 |
11 | LATS1 | 2.30253332 |
12 | PDGFRA | 2.25044257 |
13 | TGFBR2 | 2.13636188 |
14 | PTK6 | 2.13083012 |
15 | DDR2 | 2.12639043 |
16 | PRPF4B | 2.07874531 |
17 | SIK1 | 2.03576651 |
18 | CAMK1G | 1.98977643 |
19 | FGFR2 | 1.92955236 |
20 | FGFR4 | 1.92259034 |
21 | CAMK1D | 1.88735382 |
22 | DMPK | 1.68541950 |
23 | PAK4 | 1.64629326 |
24 | STK39 | 1.51656040 |
25 | RIPK1 | 1.49928220 |
26 | MTOR | 1.48998463 |
27 | STK10 | 1.41402665 |
28 | PDGFRB | 1.39259405 |
29 | BMX | 1.33281642 |
30 | MET | 1.29849707 |
31 | KSR2 | 1.28759676 |
32 | IRAK3 | 1.28720667 |
33 | BRD4 | 1.26088683 |
34 | CSF1R | 1.21566051 |
35 | * PAK2 | 1.19973365 |
36 | NEK2 | 1.19140487 |
37 | TYRO3 | 1.17237744 |
38 | EPHB2 | 1.12031206 |
39 | WNK1 | 1.09742336 |
40 | SIK2 | 1.06465875 |
41 | LRRK2 | 1.04197146 |
42 | PTK2 | 1.03391666 |
43 | CDK6 | 1.02122627 |
44 | MYLK | 1.01855289 |
45 | ERN1 | 0.98973722 |
46 | MST1R | 0.98373771 |
47 | RPS6KA2 | 0.97030325 |
48 | TRPM7 | 0.96995172 |
49 | RPS6KB2 | 0.95542066 |
50 | MARK2 | 0.95238861 |
51 | CSNK1A1L | 0.90542306 |
52 | FGFR1 | 0.88979793 |
53 | MOS | 0.88356616 |
54 | PRKD1 | 0.87868895 |
55 | MKNK1 | 0.86666090 |
56 | MAPK15 | 0.86501283 |
57 | MAP3K6 | 0.84142944 |
58 | ERBB4 | 0.83371360 |
59 | LMTK2 | 0.83078254 |
60 | PRKD2 | 0.81810663 |
61 | PKN1 | 0.80169895 |
62 | TESK1 | 0.78606027 |
63 | ROCK2 | 0.78147080 |
64 | CDK4 | 0.77365833 |
65 | ALK | 0.77104451 |
66 | DYRK1B | 0.75022700 |
67 | NEK9 | 0.71665259 |
68 | SCYL2 | 0.70927172 |
69 | MAP3K7 | 0.69331014 |
70 | MELK | 0.65156142 |
71 | CSK | 0.62622303 |
72 | STK38 | 0.62064191 |
73 | ARAF | 0.60974653 |
74 | KSR1 | 0.60626603 |
75 | PTK2B | 0.59412262 |
76 | RPS6KC1 | 0.58959456 |
77 | RPS6KL1 | 0.58959456 |
78 | UHMK1 | 0.58436963 |
79 | ERBB2 | 0.57739174 |
80 | PRKD3 | 0.56705781 |
81 | RET | 0.55986569 |
82 | BRAF | 0.55938993 |
83 | HIPK2 | 0.55705369 |
84 | FGR | 0.55335708 |
85 | PRKG2 | 0.55236996 |
86 | CDC42BPA | 0.54839610 |
87 | CDC7 | 0.54821043 |
88 | CDK9 | 0.54781342 |
89 | PASK | 0.54601632 |
90 | ROCK1 | 0.53730617 |
91 | ILK | 0.52075840 |
92 | CDK8 | 0.51212213 |
93 | LATS2 | 0.49937827 |
94 | CSNK1D | 0.49715232 |
95 | CSNK1G1 | 0.49690848 |
96 | TAOK2 | 0.49167964 |
97 | TIE1 | 0.49143053 |
98 | * STK3 | 0.48230199 |
99 | FLT3 | 0.47955167 |
100 | PRKCH | 0.46900533 |
101 | MAP4K1 | 0.46723399 |
102 | CDK7 | 0.45890168 |
103 | MAPK10 | 0.45255223 |
104 | MAPK1 | 0.45147088 |
105 | STK11 | 0.44882225 |
106 | MAPK11 | 0.44144253 |
107 | MAP2K3 | 0.43341634 |
108 | GSK3A | 0.42841554 |
109 | PAK3 | 0.40332687 |
110 | * INSR | 0.40133014 |
111 | MAPKAPK5 | 0.39761406 |
112 | CSNK1G3 | 0.39683942 |
113 | MAP3K13 | 0.39601975 |
114 | FGFR3 | 0.38743374 |
115 | AKT2 | 0.38686147 |
116 | WNK4 | 0.38102147 |
117 | CHEK1 | 0.37447786 |
118 | EPHA2 | 0.37445187 |
119 | PAK1 | 0.37376412 |
120 | * HCK | 0.37209936 |
121 | AKT3 | 0.37078293 |
122 | * SRC | 0.37047428 |
123 | CHEK2 | 0.36624105 |
124 | MAPKAPK2 | 0.36400488 |
125 | MAP3K2 | 0.35617660 |
126 | ITK | 0.34797827 |
127 | RAF1 | 0.34566042 |
128 | MAPK7 | 0.34488781 |
129 | CDK2 | 0.34093830 |
130 | PRKAA2 | 0.34061858 |
131 | MAP2K2 | 0.33852233 |
132 | * MAP3K8 | 0.33649711 |
133 | MKNK2 | 0.33071915 |
134 | AKT1 | 0.32472796 |
135 | RPS6KA6 | 0.32269210 |
136 | * CDK1 | 0.32172725 |
137 | MAP2K1 | 0.31359853 |
138 | PAK6 | 0.30702635 |
139 | PDPK1 | 0.30630778 |
Rank | Gene Set | Z-score |
---|---|---|
1 | ECM-receptor interaction_Homo sapiens_hsa04512 | 2.42465768 |
2 | Basal cell carcinoma_Homo sapiens_hsa05217 | 2.28185315 |
3 | Focal adhesion_Homo sapiens_hsa04510 | 2.16758738 |
4 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 2.12698161 |
5 | Notch signaling pathway_Homo sapiens_hsa04330 | 2.11291769 |
6 | * Chronic myeloid leukemia_Homo sapiens_hsa05220 | 1.95975268 |
7 | Small cell lung cancer_Homo sapiens_hsa05222 | 1.93194281 |
8 | Proteoglycans in cancer_Homo sapiens_hsa05205 | 1.92555049 |
9 | Adherens junction_Homo sapiens_hsa04520 | 1.84890434 |
10 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 1.80785475 |
11 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 1.79414269 |
12 | * MicroRNAs in cancer_Homo sapiens_hsa05206 | 1.79161636 |
13 | Hippo signaling pathway_Homo sapiens_hsa04390 | 1.76768574 |
14 | Thyroid cancer_Homo sapiens_hsa05216 | 1.70633477 |
15 | Lysine degradation_Homo sapiens_hsa00310 | 1.67218972 |
16 | Renal cell carcinoma_Homo sapiens_hsa05211 | 1.59713360 |
17 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 1.54995159 |
18 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 1.53347390 |
19 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 1.53066355 |
20 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 1.48699719 |
21 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 1.47068694 |
22 | Tight junction_Homo sapiens_hsa04530 | 1.43269366 |
23 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 1.41676598 |
24 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 1.40444442 |
25 | Prion diseases_Homo sapiens_hsa05020 | 1.39914716 |
26 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 1.37257687 |
27 | * Axon guidance_Homo sapiens_hsa04360 | 1.36810829 |
28 | Pancreatic cancer_Homo sapiens_hsa05212 | 1.36545609 |
29 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 1.35973192 |
30 | Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410 | 1.33881515 |
31 | Prostate cancer_Homo sapiens_hsa05215 | 1.33349049 |
32 | Colorectal cancer_Homo sapiens_hsa05210 | 1.32526823 |
33 | Amoebiasis_Homo sapiens_hsa05146 | 1.32525234 |
34 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 1.30718530 |
35 | Protein digestion and absorption_Homo sapiens_hsa04974 | 1.29065177 |
36 | * Pathways in cancer_Homo sapiens_hsa05200 | 1.25453470 |
37 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 1.23140165 |
38 | Platelet activation_Homo sapiens_hsa04611 | 1.22654774 |
39 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 1.20422148 |
40 | PI3K-Akt signaling pathway_Homo sapiens_hsa04151 | 1.19804304 |
41 | Wnt signaling pathway_Homo sapiens_hsa04310 | 1.17865386 |
42 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 1.16341833 |
43 | HTLV-I infection_Homo sapiens_hsa05166 | 1.15782935 |
44 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 1.15502329 |
45 | Other glycan degradation_Homo sapiens_hsa00511 | 1.13898051 |
46 | Insulin signaling pathway_Homo sapiens_hsa04910 | 1.12803536 |
47 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 1.12393878 |
48 | Glioma_Homo sapiens_hsa05214 | 1.08879951 |
49 | * Viral myocarditis_Homo sapiens_hsa05416 | 1.08212853 |
50 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 1.08182529 |
51 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 1.07504527 |
52 | Toxoplasmosis_Homo sapiens_hsa05145 | 1.07355066 |
53 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 1.06410404 |
54 | Bladder cancer_Homo sapiens_hsa05219 | 1.05887046 |
55 | Endometrial cancer_Homo sapiens_hsa05213 | 1.04709110 |
56 | mTOR signaling pathway_Homo sapiens_hsa04150 | 1.03973382 |
57 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 1.01718019 |
58 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 1.01137866 |
59 | Osteoclast differentiation_Homo sapiens_hsa04380 | 1.00145799 |
60 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.98772968 |
61 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.97313191 |
62 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.97162383 |
63 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.95063732 |
64 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.94439767 |
65 | Endocytosis_Homo sapiens_hsa04144 | 0.93746421 |
66 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 0.93388670 |
67 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.90125455 |
68 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 0.89986555 |
69 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.89723359 |
70 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 0.89067934 |
71 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 0.87420277 |
72 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 0.86217023 |
73 | Insulin resistance_Homo sapiens_hsa04931 | 0.83834036 |
74 | Melanoma_Homo sapiens_hsa05218 | 0.83662570 |
75 | Galactose metabolism_Homo sapiens_hsa00052 | 0.83234516 |
76 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.82448773 |
77 | AMPK signaling pathway_Homo sapiens_hsa04152 | 0.81360589 |
78 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 0.79445937 |
79 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.79434057 |
80 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.78523636 |
81 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 0.74885316 |
82 | Hepatitis B_Homo sapiens_hsa05161 | 0.74788370 |
83 | * Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.74753963 |
84 | Melanogenesis_Homo sapiens_hsa04916 | 0.73753142 |
85 | * Cell cycle_Homo sapiens_hsa04110 | 0.73431248 |
86 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.73258648 |
87 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 0.72423758 |
88 | Malaria_Homo sapiens_hsa05144 | 0.72330575 |
89 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.70354342 |
90 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.69930296 |
91 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 0.69355283 |
92 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.69334793 |
93 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.69065271 |
94 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.67999213 |
95 | Carbon metabolism_Homo sapiens_hsa01200 | 0.67353534 |
96 | * ErbB signaling pathway_Homo sapiens_hsa04012 | 0.67342622 |
97 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.67165092 |
98 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.66142600 |
99 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.65780952 |
100 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.64011560 |
101 | * Ras signaling pathway_Homo sapiens_hsa04014 | 0.62507416 |
102 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 0.60717842 |
103 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.60561813 |
104 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 0.60526687 |
105 | Apoptosis_Homo sapiens_hsa04210 | 0.60413088 |
106 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.59649479 |
107 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.59178430 |
108 | Salmonella infection_Homo sapiens_hsa05132 | 0.57516202 |
109 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 0.55450787 |
110 | * Shigellosis_Homo sapiens_hsa05131 | 0.55403948 |
111 | Long-term potentiation_Homo sapiens_hsa04720 | 0.55361304 |
112 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.52884785 |
113 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.52757882 |
114 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.52729535 |
115 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 0.51385523 |
116 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.51206704 |
117 | Spliceosome_Homo sapiens_hsa03040 | 0.49451731 |
118 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.49154997 |
119 | Gap junction_Homo sapiens_hsa04540 | 0.48121234 |
120 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.47980745 |
121 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.47368428 |
122 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.47289366 |
123 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.46455034 |
124 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.46334646 |
125 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 0.46138978 |
126 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.45351372 |
127 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.45273691 |
128 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 0.45117289 |
129 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.44840141 |