ACSF2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222)7.05162357
2L-phenylalanine catabolic process (GO:0006559)7.05162357
3erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221)6.80225059
4L-phenylalanine metabolic process (GO:0006558)6.80225059
5aromatic amino acid family catabolic process (GO:0009074)6.41588086
6triglyceride-rich lipoprotein particle remodeling (GO:0034370)6.19037823
7kynurenine metabolic process (GO:0070189)5.89203801
8low-density lipoprotein particle clearance (GO:0034383)5.88131283
9tryptophan catabolic process (GO:0006569)5.87134989
10indole-containing compound catabolic process (GO:0042436)5.87134989
11indolalkylamine catabolic process (GO:0046218)5.87134989
12alpha-linolenic acid metabolic process (GO:0036109)5.84780817
13bile acid biosynthetic process (GO:0006699)5.74088044
14glyoxylate metabolic process (GO:0046487)5.52767076
15sulfur amino acid catabolic process (GO:0000098)5.52644619
16tryptophan metabolic process (GO:0006568)5.49181836
17urea cycle (GO:0000050)5.43708431
18urea metabolic process (GO:0019627)5.43708431
19high-density lipoprotein particle remodeling (GO:0034375)5.34490215
20negative regulation of fibrinolysis (GO:0051918)5.22660176
21cysteine metabolic process (GO:0006534)5.15597406
22complement activation, alternative pathway (GO:0006957)5.15510072
23regulation of protein activation cascade (GO:2000257)5.08486354
24peptidyl-glutamic acid carboxylation (GO:0017187)5.07121232
25protein carboxylation (GO:0018214)5.07121232
26fatty acid beta-oxidation using acyl-CoA oxidase (GO:0033540)5.01151011
27nitrogen cycle metabolic process (GO:0071941)4.98348837
28serine family amino acid catabolic process (GO:0009071)4.97738290
29regulation of fibrinolysis (GO:0051917)4.97355050
30regulation of triglyceride catabolic process (GO:0010896)4.94569824
31bile acid metabolic process (GO:0008206)4.92053730
32regulation of complement activation (GO:0030449)4.78853415
33lysine catabolic process (GO:0006554)4.77021047
34lysine metabolic process (GO:0006553)4.77021047
35homocysteine metabolic process (GO:0050667)4.73844360
36reverse cholesterol transport (GO:0043691)4.70817107
37diacylglycerol metabolic process (GO:0046339)4.70281175
38amino-acid betaine metabolic process (GO:0006577)4.67607308
39aromatic amino acid family metabolic process (GO:0009072)4.64166350
40negative regulation of sterol transport (GO:0032372)4.60087922
41negative regulation of cholesterol transport (GO:0032375)4.60087922
42regulation of cholesterol esterification (GO:0010872)4.59492145
43triglyceride homeostasis (GO:0070328)4.58373202
44acylglycerol homeostasis (GO:0055090)4.58373202
45vitamin transmembrane transport (GO:0035461)4.56455970
46macromolecular complex remodeling (GO:0034367)4.53358483
47plasma lipoprotein particle remodeling (GO:0034369)4.53358483
48protein-lipid complex remodeling (GO:0034368)4.53358483
49fatty acid homeostasis (GO:0055089)4.50489261
50alpha-amino acid catabolic process (GO:1901606)4.47575643
51phospholipid efflux (GO:0033700)4.43119514
52tyrosine metabolic process (GO:0006570)4.42049376
53NADH metabolic process (GO:0006734)4.32946089
54ethanol oxidation (GO:0006069)4.30544017
55glycine metabolic process (GO:0006544)4.28961869
56cellular ketone body metabolic process (GO:0046950)4.28445161
57plasma lipoprotein particle clearance (GO:0034381)4.26601623
58bile acid and bile salt transport (GO:0015721)4.25958086
59coenzyme catabolic process (GO:0009109)4.22286288
60cellular amino acid catabolic process (GO:0009063)4.17761534
61regulation of cholesterol homeostasis (GO:2000188)4.12426926
62cellular glucuronidation (GO:0052695)4.11588735
63benzene-containing compound metabolic process (GO:0042537)4.10480060
64cholesterol efflux (GO:0033344)4.09718918
65indolalkylamine metabolic process (GO:0006586)4.06766024
66glutamate metabolic process (GO:0006536)4.05757842
67ethanol metabolic process (GO:0006067)4.03981388
68serine family amino acid metabolic process (GO:0009069)4.03071581
69cellular modified amino acid catabolic process (GO:0042219)4.02847302
70imidazole-containing compound metabolic process (GO:0052803)3.99121520
71dicarboxylic acid biosynthetic process (GO:0043650)3.98177391
72plasma lipoprotein particle assembly (GO:0034377)3.96965682
73drug catabolic process (GO:0042737)3.96808638
74cellular biogenic amine catabolic process (GO:0042402)3.93833286
75amine catabolic process (GO:0009310)3.93833286
76positive regulation of lipid catabolic process (GO:0050996)3.87228195
77acetyl-CoA metabolic process (GO:0006084)3.86615701
78triglyceride catabolic process (GO:0019433)3.86235296
79regulation of cholesterol biosynthetic process (GO:0045540)3.81564582
80serine family amino acid biosynthetic process (GO:0009070)3.81067094
81regulation of bile acid biosynthetic process (GO:0070857)3.80135763
82cholesterol homeostasis (GO:0042632)3.79375715
83positive regulation of lipoprotein lipase activity (GO:0051006)3.79231615
84positive regulation of triglyceride lipase activity (GO:0061365)3.79231615
85phospholipid homeostasis (GO:0055091)3.77729669
86arginine metabolic process (GO:0006525)3.76218563
87neutral lipid catabolic process (GO:0046461)3.75754751
88acylglycerol catabolic process (GO:0046464)3.75754751
89short-chain fatty acid metabolic process (GO:0046459)3.75702920
90positive regulation of fatty acid beta-oxidation (GO:0032000)3.74974728
91epoxygenase P450 pathway (GO:0019373)3.73485578
92sterol homeostasis (GO:0055092)3.73286482
93complement activation, classical pathway (GO:0006958)3.72396831
94organic acid catabolic process (GO:0016054)3.71408527
95carboxylic acid catabolic process (GO:0046395)3.71408527
96very-low-density lipoprotein particle assembly (GO:0034379)3.70855647
97ketone body metabolic process (GO:1902224)3.70302123
98positive regulation of fatty acid biosynthetic process (GO:0045723)3.66968541
99cytolysis (GO:0019835)3.66527192
100fibrinolysis (GO:0042730)3.66430470
101complement activation (GO:0006956)3.65050037
102flavonoid metabolic process (GO:0009812)3.63765111
103fatty acid beta-oxidation (GO:0006635)3.63728641
1042-oxoglutarate metabolic process (GO:0006103)3.62904682
105intestinal cholesterol absorption (GO:0030299)3.62368854
106protein-lipid complex assembly (GO:0065005)3.60827224
107regulation of cholesterol storage (GO:0010885)3.59192517
108fatty acid oxidation (GO:0019395)3.58751727
109glucuronate metabolic process (GO:0019585)3.58525462
110uronic acid metabolic process (GO:0006063)3.58525462
111negative regulation of lipase activity (GO:0060192)3.57729629
112intestinal absorption (GO:0050892)3.54837744
113plasma lipoprotein particle organization (GO:0071827)3.53996909
114monocarboxylic acid catabolic process (GO:0072329)3.52796526
115regulation of cholesterol metabolic process (GO:0090181)3.52275050
116regulation of systemic arterial blood pressure by renin-angiotensin (GO:0003081)3.41148870
117protein-lipid complex subunit organization (GO:0071825)3.40248662
118low-density lipoprotein particle remodeling (GO:0034374)3.33177498
119oxaloacetate metabolic process (GO:0006107)3.33024926
120oligosaccharide catabolic process (GO:0009313)3.29965117
121triglyceride biosynthetic process (GO:0019432)3.29951410
122positive regulation of mitochondrial calcium ion concentration (GO:0051561)3.26054840
123acylglycerol biosynthetic process (GO:0046463)3.22383491
124neutral lipid biosynthetic process (GO:0046460)3.22383491
125proline metabolic process (GO:0006560)3.18208930
126lipoprotein metabolic process (GO:0042157)3.17830934
127regulation of apoptotic cell clearance (GO:2000425)3.17709534
128positive regulation of fatty acid metabolic process (GO:0045923)3.12919431
129triglyceride metabolic process (GO:0006641)3.12137275
130positive regulation of triglyceride metabolic process (GO:0090208)3.09342118
131desmosome organization (GO:0002934)3.07887839
132regulation of triglyceride metabolic process (GO:0090207)3.01988219
133regulation of fatty acid biosynthetic process (GO:0042304)3.01952686
134acylglycerol metabolic process (GO:0006639)2.99741734
135angiotensin maturation (GO:0002003)2.99490982
136neutral lipid metabolic process (GO:0006638)2.93945570
137regulation of sequestering of triglyceride (GO:0010889)2.93073061
138biotin metabolic process (GO:0006768)2.91456936
139tricarboxylic acid metabolic process (GO:0072350)2.90690614
140primary alcohol metabolic process (GO:0034308)2.84171477
141carnitine shuttle (GO:0006853)2.83227943
142fat-soluble vitamin biosynthetic process (GO:0042362)2.82531768
143acyl-CoA biosynthetic process (GO:0071616)2.79261959
144thioester biosynthetic process (GO:0035384)2.79261959
145drug metabolic process (GO:0017144)2.79082522
146fatty acid transmembrane transport (GO:1902001)2.79074760
147very long-chain fatty acid metabolic process (GO:0000038)2.79033947
148positive regulation of lipid storage (GO:0010884)2.74303836
149positive regulation of steroid metabolic process (GO:0045940)2.74300526
150positive regulation of cholesterol efflux (GO:0010875)2.72256386
151negative regulation of fatty acid transport (GO:2000192)2.71968396
152negative regulation of fatty acid biosynthetic process (GO:0045717)2.71546384

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1* RXR_22158963_ChIP-Seq_LIVER_Mouse7.97071071
2* PPARA_22158963_ChIP-Seq_LIVER_Mouse7.00649868
3LXR_22158963_ChIP-Seq_LIVER_Mouse6.22840811
4EGR1_23403033_ChIP-Seq_LIVER_Mouse6.11376304
5PPARG_19300518_ChIP-PET_3T3-L1_Mouse5.58995276
6FOXO1_23066095_ChIP-Seq_LIVER_Mouse4.97727880
7CEBPA_23403033_ChIP-Seq_LIVER_Mouse4.49535772
8NR1I2_20693526_ChIP-Seq_LIVER_Mouse3.98247196
9CEBPB_23403033_ChIP-Seq_LIVER_Mouse3.46097475
10TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse2.41242698
11TCF7L2_21901280_ChIP-Seq_H4IIE_Rat2.01905843
12ESR1_17901129_ChIP-ChIP_LIVER_Mouse11.2143968
13CLOCK_20551151_ChIP-Seq_293T_Human1.99155690
14HNF4A_19761587_ChIP-ChIP_CACO-2_Human1.96442122
15STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.75380759
16TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.64351029
17* FOXA2_19822575_ChIP-Seq_HepG2_Human1.59706512
18* P63_26484246_Chip-Seq_KERATINOCYTES_Human1.59191673
19TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.58770703
20TRIM28_21343339_ChIP-Seq_HEK293_Human1.52464072
21THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.47557319
22* HNF4A_19822575_ChIP-Seq_HepG2_Human1.39413147
23CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human1.38450755
24HIF1A_21447827_ChIP-Seq_MCF-7_Human1.34491772
25SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.31775048
26P68_20966046_ChIP-Seq_HELA_Human1.29281129
27SOX2_20726797_ChIP-Seq_SW620_Human1.26917149
28SOX2_27498859_Chip-Seq_STOMACH_Mouse1.26349171
29ZNF263_19887448_ChIP-Seq_K562_Human1.21190986
30* SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.20991920
31RARG_19884340_ChIP-ChIP_MEFs_Mouse1.20962526
32ESR1_15608294_ChIP-ChIP_MCF-7_Human1.20920032
33VDR_21846776_ChIP-Seq_THP-1_Human1.20512875
34GATA1_22025678_ChIP-Seq_K562_Human1.20247825
35SMC4_20622854_ChIP-Seq_HELA_Human1.19366691
36STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.18423508
37KDM2B_26808549_Chip-Seq_SUP-B15_Human1.18242383
38RXRA_24833708_ChIP-Seq_LIVER_Mouse1.17805768
39TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.16636679
40RUNX1_27514584_Chip-Seq_MCF-7_Human1.16452079
41RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.15601119
42MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.15009366
43UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.11133236
44DNAJC2_21179169_ChIP-ChIP_NT2_Human1.09390800
45NR0B1_18358816_ChIP-ChIP_MESCs_Mouse1.07167801
46CTCF_27219007_Chip-Seq_ERYTHROID_Human1.06813022
47ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.06739887
48IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.05979642
49ELF1_20517297_ChIP-Seq_JURKAT_Human1.05515201
50TP63_22573176_ChIP-Seq_HFKS_Human1.05478160
51SA1_27219007_Chip-Seq_ERYTHROID_Human1.04619910
52HTT_18923047_ChIP-ChIP_STHdh_Human1.04060132
53ESR2_21235772_ChIP-Seq_MCF-7_Human1.03567164
54KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.03241490
55CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.02067129
56LXR_22292898_ChIP-Seq_THP-1_Human1.02032211
57* TP53_22127205_ChIP-Seq_IMR90_Human1.01289601
58IRF8_22096565_ChIP-ChIP_GC-B_Human1.00655744
59KLF4_18358816_ChIP-ChIP_MESCs_Mouse0.99295569
60STAT3_1855785_ChIP-Seq_MESCs_Mouse0.96847991
61NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human0.96542779
62GATA4_25053715_ChIP-Seq_YYC3_Human0.96290883
63CDX2_20551321_ChIP-Seq_CACO-2_Human0.95546051
64SA1_27219007_Chip-Seq_Bcells_Human0.93478008
65TCF7_22412390_ChIP-Seq_EML_Mouse0.91750013
66* NFIB_24661679_ChIP-Seq_LUNG_Mouse0.91371947
67PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse0.91108373
68E2F1_20622854_ChIP-Seq_HELA_Human0.89966367
69CTCF_27219007_Chip-Seq_Bcells_Human0.88864551
70GATA2_20887958_ChIP-Seq_HPC-7_Mouse0.88616161
71ESRRB_18555785_ChIP-Seq_MESCs_Mouse0.88591469
72CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse0.87794965
73PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse0.86787142
74SREBP2_21459322_ChIP-Seq_LIVER_Mouse0.86325745
75NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse0.86269157
76RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human0.83037446
77ZNF652_21678463_ChIP-ChIP_ZR75-1_Human0.81616487
78PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse0.81491663
79RARA_24833708_ChIP-Seq_LIVER_Mouse0.80462420
80RACK7_27058665_Chip-Seq_MCF-7_Human0.78979682
81TP63_17297297_ChIP-ChIP_HaCaT_Human0.78295086
82SALL4_18804426_ChIP-ChIP_XEN_Mouse0.76703762
83FOXO3_23340844_ChIP-Seq_DLD1_Human0.74973232
84SREBP1_19666523_ChIP-Seq_LIVER_Mouse0.74651297
85ESR1_21235772_ChIP-Seq_MCF-7_Human0.73356550
86* GATA6_25053715_ChIP-Seq_YYC3_Human0.72107738
87RARB_24833708_ChIP-Seq_LIVER_Mouse0.71726231
88ESR1_20079471_ChIP-ChIP_T-47D_Human0.69190498
89TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse0.68627257
90POU5F1_18700969_ChIP-ChIP_MESCs_Mouse0.68236471
91AUTS2_25519132_ChIP-Seq_293T-REX_Human0.67908927
92AR_21915096_ChIP-Seq_LNCaP-1F5_Human0.67855736
93PPAR_26484153_Chip-Seq_NCI-H1993_Human0.65766946
94BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.64650576
95BMI1_19503595_ChIP-Seq_MEFsC_Mouse0.61648285
96Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse0.61535015
97KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human0.60496230
98PPARD_23208498_ChIP-Seq_MDA-MB-231_Human0.59176979
99FOXA1_26743006_Chip-Seq_LNCaP-abl_Human0.58340528
100RAD21_21589869_ChIP-Seq_MESCs_Mouse0.57711773
101GATA1_19941827_ChIP-Seq_MEL_Mouse0.57589859
102GATA1_19941826_ChIP-Seq_K562_Human0.56646363
103* TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.55537600
104* ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human0.55179640
105CEBPB_22108803_ChIP-Seq_LS180_Human0.54683933
106* FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human0.54578524
107ELK3_25401928_ChIP-Seq_HUVEC_Human0.54461747
108BRD4_27068464_Chip-Seq_AML-cells_Mouse0.53964873
109BCOR_27268052_Chip-Seq_Bcells_Human0.53823301
110GATA2_19941826_ChIP-Seq_K562_Human0.53334316
111FOXA1_25552417_ChIP-Seq_VCAP_Human0.52489803
112TBX20_22328084_ChIP-Seq_HEART_Mouse0.52275483
113TBX20_22080862_ChIP-Seq_HEART_Mouse0.52275483
114CREB1_26743006_Chip-Seq_LNCaP_Human0.51668753
115EGR1_19032775_ChIP-ChIP_M12_Human0.51038524
116E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human0.50944129
117SMAD2/3_21741376_ChIP-Seq_ESCs_Human0.49057593
118ATF3_27146783_Chip-Seq_COLON_Human0.49046677
119PPARG_20887899_ChIP-Seq_3T3-L1_Mouse0.47925000
120* KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human0.47912563
121FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human0.47170495
122PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse0.46711394
123BCL6_27268052_Chip-Seq_Bcells_Human0.45429784
124CREB1_26743006_Chip-Seq_LNCaP-abl_Human0.45028355
125GATA3_20176728_ChIP-ChIP_TSCs_Mouse0.44945085
126KAP1_22055183_ChIP-Seq_ESCs_Mouse0.44636748
127TCF3_18692474_ChIP-Seq_MEFs_Mouse0.44231817
128CEBPB_26923725_Chip-Seq_MACROPHAGESS_Mouse0.44047710
129KDM2B_26808549_Chip-Seq_HPB-ALL_Human0.43863439
130GATA3_24758297_ChIP-Seq_MCF-7_Human0.43563257
131MYC_27129775_Chip-Seq_CORNEA_Mouse0.43168790
132P300_27058665_Chip-Seq_ZR-75-30cells_Human0.43061519
133* TET1_21451524_ChIP-Seq_MESCs_Mouse0.42160681

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002139_abnormal_hepatobiliary_system7.95176145
2MP0005360_urolithiasis7.43879858
3MP0005085_abnormal_gallbladder_physiolo6.23208150
4MP0005365_abnormal_bile_salt6.01413626
5MP0008875_abnormal_xenobiotic_pharmacok4.98835068
6MP0003806_abnormal_nucleotide_metabolis3.99500526
7MP0003252_abnormal_bile_duct3.94299601
8MP0010329_abnormal_lipoprotein_level3.62575357
9MP0009840_abnormal_foam_cell3.37134304
10MP0005058_abnormal_lysosome_morphology3.03723944
11MP0001666_abnormal_nutrient_absorption2.73351217
12MP0005083_abnormal_biliary_tract2.72399972
13MP0005332_abnormal_amino_acid2.65664933
14MP0003191_abnormal_cellular_cholesterol2.38360106
15MP0003195_calcinosis2.27514702
16MP0000609_abnormal_liver_physiology2.24203129
17MP0002118_abnormal_lipid_homeostasis2.11547183
18MP0004019_abnormal_vitamin_homeostasis2.02809500
19MP0005319_abnormal_enzyme/_coenzyme1.90430984
20MP0003705_abnormal_hypodermis_morpholog1.84670959
21MP0003868_abnormal_feces_composition1.79774705
22MP0002138_abnormal_hepatobiliary_system1.76356272
23MP0005584_abnormal_enzyme/coenzyme_acti1.55610052
24MP0005409_darkened_coat_color1.39464407
25MP0001764_abnormal_homeostasis1.39025574
26MP0004782_abnormal_surfactant_physiolog1.36472132
27MP0000003_abnormal_adipose_tissue1.35731721
28MP0009643_abnormal_urine_homeostasis1.31449099
29MP0005451_abnormal_body_composition1.30730716
30MP0008438_abnormal_cutaneous_collagen1.26873081
31MP0000598_abnormal_liver_morphology1.23122115
32MP0000751_myopathy1.22915732
33MP0005670_abnormal_white_adipose1.22686523
34MP0003172_abnormal_lysosome_physiology1.22280878
35MP0009697_abnormal_copulation1.18504315
36MP0003186_abnormal_redox_activity1.15430883
37MP0004272_abnormal_basement_membrane1.12483482
38MP0005647_abnormal_sex_gland1.12282926
39MP0003011_delayed_dark_adaptation1.12218054
40MP0002254_reproductive_system_inflammat1.11338404
41MP0006138_congestive_heart_failure1.11086653
42MP0005330_cardiomyopathy1.10291863
43MP0010368_abnormal_lymphatic_system1.08268986
44MP0003656_abnormal_erythrocyte_physiolo1.07847503
45MP0000566_synostosis1.07085071
46MP0004043_abnormal_pH_regulation1.06119896
47MP0003183_abnormal_peptide_metabolism1.04267507
48MP0004130_abnormal_muscle_cell1.00476271
49MP0003959_abnormal_lean_body0.98264625
50MP0009763_increased_sensitivity_to0.94997028
51MP0000013_abnormal_adipose_tissue0.94105393
52MP0009764_decreased_sensitivity_to0.92938806
53MP0003950_abnormal_plasma_membrane0.87774633
54MP0000604_amyloidosis0.85944533
55MP0002971_abnormal_brown_adipose0.85898482
56MP0008469_abnormal_protein_level0.84707902
57MP0009642_abnormal_blood_homeostasis0.84638171
58MP0009053_abnormal_anal_canal0.81731215
59MP0005636_abnormal_mineral_homeostasis0.81711348
60MP0000858_altered_metastatic_potential0.81075905
61MP0002933_joint_inflammation0.80496293
62MP0010155_abnormal_intestine_physiology0.80349030
63MP0005666_abnormal_adipose_tissue0.79891674
64MP0006036_abnormal_mitochondrial_physio0.79741012
65MP0002098_abnormal_vibrissa_morphology0.76915380
66MP0002078_abnormal_glucose_homeostasis0.76626173
67MP0005334_abnormal_fat_pad0.75975597
68MP0005376_homeostasis/metabolism_phenot0.74228889
69MP0003566_abnormal_cell_adhesion0.73166293
70MP0001216_abnormal_epidermal_layer0.71518983
71MP0000639_abnormal_adrenal_gland0.70850555
72MP0003879_abnormal_hair_cell0.70351235
73MP0005165_increased_susceptibility_to0.69604859
74MP0005266_abnormal_metabolism0.69591734
75MP0002166_altered_tumor_susceptibility0.69224277
76MP0002089_abnormal_postnatal_growth/wei0.65716780
77MP0005164_abnormal_response_to0.65568997
78MP0009765_abnormal_xenobiotic_induced0.64714986
79MP0001661_extended_life_span0.64543603
80MP0001765_abnormal_ion_homeostasis0.64504772
81MP0005501_abnormal_skin_physiology0.64424351
82MP0001756_abnormal_urination0.64059820
83MP0005452_abnormal_adipose_tissue0.63413596
84MP0002132_abnormal_respiratory_system0.62879912
85MP0000747_muscle_weakness0.62717509
86MP0004264_abnormal_extraembryonic_tissu0.62015981
87MP0003279_aneurysm0.61174504
88MP0010234_abnormal_vibrissa_follicle0.61008652
89MP0005220_abnormal_exocrine_pancreas0.59857733
90MP0005448_abnormal_energy_balance0.59240403
91MP0009785_altered_susceptibility_to0.57986829
92MP0005535_abnormal_body_temperature0.57579787
93MP0000678_abnormal_parathyroid_gland0.57309462
94MP0005076_abnormal_cell_differentiation0.57177539
95MP0004087_abnormal_muscle_fiber0.56996720
96MP0005408_hypopigmentation0.55996317
97MP0002998_abnormal_bone_remodeling0.55467683
98MP0002796_impaired_skin_barrier0.55299398
99MP0005084_abnormal_gallbladder_morpholo0.55281581
100MP0002896_abnormal_bone_mineralization0.55272654
101MP0002136_abnormal_kidney_physiology0.55198941
102MP0009115_abnormal_fat_cell0.54996407
103MP0000343_altered_response_to0.54286606
104MP0001533_abnormal_skeleton_physiology0.53760118
105MP0002837_dystrophic_cardiac_calcinosis0.53669604
106MP0003690_abnormal_glial_cell0.53025765
107MP0003638_abnormal_response/metabolism_0.52465019
108MP0003300_gastrointestinal_ulcer0.52098677
109MP0005248_abnormal_Harderian_gland0.52023459
110MP0004185_abnormal_adipocyte_glucose0.50931039
111MP0005464_abnormal_platelet_physiology0.48523223
112MP0006035_abnormal_mitochondrial_morpho0.47336191
113MP0002970_abnormal_white_adipose0.46815692
114MP0002822_catalepsy0.46596732
115MP0003453_abnormal_keratinocyte_physiol0.45025560
116MP0008874_decreased_physiological_sensi0.44825796
117MP0002876_abnormal_thyroid_physiology0.44742117
118MP0002928_abnormal_bile_duct0.43254079
119MP0008873_increased_physiological_sensi0.43006033
120MP0005395_other_phenotype0.42056200
121MP0009384_cardiac_valve_regurgitation0.42023774
122MP0002060_abnormal_skin_morphology0.41502137
123MP0009672_abnormal_birth_weight0.41067555
124MP0003953_abnormal_hormone_level0.40236942
125MP0000249_abnormal_blood_vessel0.39606528
126MP0003329_amyloid_beta_deposits0.39109259
127MP0000579_abnormal_nail_morphology0.38528842
128MP0005023_abnormal_wound_healing0.38021372
129MP0005166_decreased_susceptibility_to0.37481193
130MP0003436_decreased_susceptibility_to0.36334487
131MP0002168_other_aberrant_phenotype0.35858200
132MP0001853_heart_inflammation0.35515814
133MP0005375_adipose_tissue_phenotype0.34716678
134MP0003724_increased_susceptibility_to0.33606492
135MP0005167_abnormal_blood-brain_barrier0.33328808
136MP0002269_muscular_atrophy0.33247933
137MP0001243_abnormal_dermal_layer0.33227390
138MP0004947_skin_inflammation0.32967368
139MP0003075_altered_response_to0.32025696
140MP0008872_abnormal_physiological_respon0.31441308
141MP0000230_abnormal_systemic_arterial0.31111713

Predicted human phenotypes

RankGene SetZ-score
1Deep venous thrombosis (HP:0002625)7.15131420
2Intrahepatic cholestasis (HP:0001406)7.05510989
3Abnormality of aromatic amino acid family metabolism (HP:0004338)6.89672611
4Abnormality of monocarboxylic acid metabolism (HP:0010996)6.53598770
5Hypobetalipoproteinemia (HP:0003563)6.20143804
6Xanthomatosis (HP:0000991)6.16698895
7Prolonged partial thromboplastin time (HP:0003645)5.91216381
8Hyperlipoproteinemia (HP:0010980)5.38461651
9Complement deficiency (HP:0004431)5.31947657
10Hyperammonemia (HP:0001987)4.79311104
11Hypolipoproteinemia (HP:0010981)4.74668104
12Hyperglycinemia (HP:0002154)4.42594565
13Epidermoid cyst (HP:0200040)4.42421264
14Hyperglycinuria (HP:0003108)4.35858039
15Abnormality of the level of lipoprotein cholesterol (HP:0010979)4.33144123
16Abnormality of glutamine family amino acid metabolism (HP:0010902)4.31783648
17Ketosis (HP:0001946)4.29620216
18Joint hemorrhage (HP:0005261)4.28398640
19Hypoalphalipoproteinemia (HP:0003233)4.22696898
20Abnormality of sulfur amino acid metabolism (HP:0004339)4.20706591
21Abnormality of serine family amino acid metabolism (HP:0010894)4.17826205
22Abnormality of glycine metabolism (HP:0010895)4.17826205
23Abnormality of the common coagulation pathway (HP:0010990)4.06649407
24Fat malabsorption (HP:0002630)3.98970515
25Hypoglycemic coma (HP:0001325)3.98252893
26Abnormality of aspartate family amino acid metabolism (HP:0010899)3.95506564
27Abnormality of methionine metabolism (HP:0010901)3.90585880
28Abnormality of complement system (HP:0005339)3.87976434
29Abnormality of pyrimidine metabolism (HP:0004353)3.61462997
30Hypercholesterolemia (HP:0003124)3.58261569
31Abnormality of fatty-acid metabolism (HP:0004359)3.57682271
32Abnormality of long-chain fatty-acid metabolism (HP:0010964)3.56808905
33Abnormality of the intrinsic pathway (HP:0010989)3.48855628
34Conjugated hyperbilirubinemia (HP:0002908)3.44477676
35Myocardial infarction (HP:0001658)3.19694321
36Ketoacidosis (HP:0001993)3.14355873
37Hyperbilirubinemia (HP:0002904)3.13098278
38Hypochromic microcytic anemia (HP:0004840)3.02476688
39Abnormality of nucleobase metabolism (HP:0010932)2.97259309
40Delayed CNS myelination (HP:0002188)2.95990739
41Steatorrhea (HP:0002570)2.94761767
42Vacuolated lymphocytes (HP:0001922)2.94703174
43Abnormality of serum amino acid levels (HP:0003112)2.90108989
44Dysostosis multiplex (HP:0000943)2.86776530
45Hepatocellular carcinoma (HP:0001402)2.84561585
46Skin nodule (HP:0200036)2.80985062
47Metabolic acidosis (HP:0001942)2.78828385
48Abnormality of dicarboxylic acid metabolism (HP:0010995)2.78231100
49Dicarboxylic aciduria (HP:0003215)2.78231100
50Exercise-induced myalgia (HP:0003738)2.71972446
51Spontaneous abortion (HP:0005268)2.65612635
52Abnormality of purine metabolism (HP:0004352)2.65157465
53Rhabdomyolysis (HP:0003201)2.64251560
54Vertebral compression fractures (HP:0002953)2.63661309
55Abnormality of mucopolysaccharide metabolism (HP:0011020)2.62244470
56Abnormality of polysaccharide metabolism (HP:0011012)2.62244470
57Abnormality of glycosaminoglycan metabolism (HP:0004371)2.62244470
58Mucopolysacchariduria (HP:0008155)2.61927621
59Urinary glycosaminoglycan excretion (HP:0003541)2.61927621
60Systemic lupus erythematosus (HP:0002725)2.61502999
61Abnormality of liposaccharide metabolism (HP:0010968)2.59759184
62Abnormality of glycosphingolipid metabolism (HP:0004343)2.59759184
63Abnormality of glycolipid metabolism (HP:0010969)2.59759184
64Spastic diplegia (HP:0001264)2.55362723
65Lethargy (HP:0001254)2.50823025
66Flat acetabular roof (HP:0003180)2.50584884
67Mitral stenosis (HP:0001718)2.47445516
68Neonatal onset (HP:0003623)2.47163533
69Myoglobinuria (HP:0002913)2.46179777
70Malnutrition (HP:0004395)2.42522936
71Acanthocytosis (HP:0001927)2.41748235
72Vascular calcification (HP:0004934)2.39245941
73Distal lower limb muscle weakness (HP:0009053)2.39177712
74Asymmetric septal hypertrophy (HP:0001670)2.38716188
75Esophageal varix (HP:0002040)2.38248467
76Gout (HP:0001997)2.37269574
77Abnormal gallbladder morphology (HP:0012437)2.32965166
78Cholelithiasis (HP:0001081)2.32345464
79Acanthosis nigricans (HP:0000956)2.31884526
80Abnormality of carpal bone ossification (HP:0006257)2.31662760
81Axonal loss (HP:0003447)2.30370245
82Hypoglycemic seizures (HP:0002173)2.28742754
83Right ventricular cardiomyopathy (HP:0011663)2.27296224
84Irritability (HP:0000737)2.25293132
85Abnormal gallbladder physiology (HP:0012438)2.21503521
86Cholecystitis (HP:0001082)2.21503521
87Hydroxyprolinuria (HP:0003080)2.20298398
88Abnormality of proline metabolism (HP:0010907)2.20298398
89Hemorrhage of the eye (HP:0011885)2.19685833
90Abnormal cartilage morphology (HP:0002763)2.18028055
91Glomerulonephritis (HP:0000099)2.17305864
92Sensorimotor neuropathy (HP:0007141)2.15290704
93Cardiovascular calcification (HP:0011915)2.15219501
94Late onset (HP:0003584)2.14417641
95Protrusio acetabuli (HP:0003179)2.13382406
96Pancreatitis (HP:0001733)2.09316919
97Gingival bleeding (HP:0000225)2.08675119
98Cerebral edema (HP:0002181)2.07832214
99Increased serum pyruvate (HP:0003542)2.07233167
100Recurrent gram-negative bacterial infections (HP:0005420)2.06854613
101Vomiting (HP:0002013)2.04628977
102Amyloidosis (HP:0011034)2.04142575
103Nausea (HP:0002018)2.02735766
104Cervical subluxation (HP:0003308)2.02509882
105Brushfield spots (HP:0001088)1.99045289
106Menorrhagia (HP:0000132)1.98004438
107Purpura (HP:0000979)1.97694613
108Abnormal tarsal ossification (HP:0008369)1.97672346
109Generalized aminoaciduria (HP:0002909)1.96762158
110Pigmentary retinal degeneration (HP:0001146)1.96567134
111Hyperinsulinemic hypoglycemia (HP:0000825)1.95320047
112Growth hormone excess (HP:0000845)1.94397971
113Thrombophlebitis (HP:0004418)1.93849994
114Abnormal ossification of hand bones (HP:0005921)1.93003027
115Abnormality of the gallbladder (HP:0005264)1.92837515
116Cerebral aneurysm (HP:0004944)1.91643228
117Muscle stiffness (HP:0003552)1.91109822
118Stridor (HP:0010307)1.90560762
119Abnormality of glycolysis (HP:0004366)1.90063728
120Ulnar deviation of the wrist (HP:0003049)1.89878801
121Widely patent fontanelles and sutures (HP:0004492)1.89484463
122Poikilocytosis (HP:0004447)1.88999175
123J-shaped sella turcica (HP:0002680)1.88015757
124Enlarged kidneys (HP:0000105)1.87899563
125Polycythemia (HP:0001901)1.87500233
126Neonatal death (HP:0003811)1.86432591
127Protuberant abdomen (HP:0001538)1.86317091
128Abdominal distention (HP:0003270)1.84669189
129Thin bony cortex (HP:0002753)1.83306438
130Rickets (HP:0002748)1.82871034
131Abnormality of iron homeostasis (HP:0011031)1.82388860
132Hyperglycemia (HP:0003074)1.82348798
133Abnormality of transition element cation homeostasis (HP:0011030)1.81646830
134Opisthotonus (HP:0002179)1.81148381
135Ovoid vertebral bodies (HP:0003300)1.80503713
136Abnormal enzyme/coenzyme activity (HP:0012379)1.80308600
137Increased cerebral lipofuscin (HP:0011813)1.79365633
138Abnormal hand bone ossification (HP:0010660)1.79201561
139Hypertriglyceridemia (HP:0002155)1.78633379
140Asymmetry of the thorax (HP:0001555)1.78456638
141Elevated hepatic transaminases (HP:0002910)1.77780345
142Nephritis (HP:0000123)1.76237602
143Facial shape deformation (HP:0011334)1.75201126
144Potter facies (HP:0002009)1.75201126
145Pathologic fracture (HP:0002756)1.74137490
146Abnormality of the periventricular white matter (HP:0002518)1.73868163
147Multiple lipomas (HP:0001012)1.73849058
148Abnormality of vitamin metabolism (HP:0100508)1.72398364
149Alkalosis (HP:0001948)1.71797167
150Renal cortical cysts (HP:0000803)1.71441149
151Pseudobulbar signs (HP:0002200)1.69552579
152Stroke (HP:0001297)1.69546027
153Cerebral palsy (HP:0100021)1.68827950
154Focal segmental glomerulosclerosis (HP:0000097)1.68803329
155Increased neuronal autofluorescent lipopigment (HP:0002074)1.68611524
156Wide cranial sutures (HP:0010537)1.68527229
157Paraparesis (HP:0002385)1.68011652
158Increased serum ferritin (HP:0003281)1.67738466

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BCKDK5.73598444
2ERN15.02264931
3SIK14.29754242
4FGFR43.95764342
5TRIB33.23552394
6PKN22.82326446
7TAOK32.24161932
8MAP3K102.19506807
9MAPKAPK32.09773563
10BLK1.98269370
11ERBB41.89191907
12LATS11.84541348
13MST1R1.81366154
14INSRR1.78080416
15PTK61.76088730
16MAPK111.73620408
17FLT31.72646628
18GRK61.70689408
19TESK11.49491417
20TYK21.47038216
21NME21.46898810
22RIPK11.42181020
23MAP2K41.37433296
24KDR1.36795461
25ICK1.35749308
26SMG11.35254310
27MAP3K71.29863232
28CAMK1D1.29199901
29FGFR21.20548986
30FRK1.19813328
31MAP4K11.16279728
32CDK61.12802431
33EPHB11.12591202
34PRKAA21.11665427
35NEK91.10133924
36JAK11.08809179
37CDC42BPA1.06863140
38JAK21.04852906
39TGFBR21.04468949
40MAP2K31.01832884
41OBSCN0.99403002
42WNK40.98210515
43CDK120.96978329
44PIM20.96294194
45CSK0.95125172
46TBK10.92600598
47PIK3CG0.89345319
48TESK20.88453657
49TIE10.87481895
50ZAP700.83322072
51MAP3K110.82739116
52ERBB20.82094301
53MAPK150.81605825
54CSF1R0.81502201
55FGFR30.80424077
56MTOR0.79937776
57PDGFRA0.79534741
58CDK40.79246808
59BMX0.79124455
60TYRO30.77348930
61MAPK40.77140536
62PINK10.76511396
63PRPF4B0.75981556
64DYRK1B0.75913733
65MET0.75443952
66ABL20.75344310
67EEF2K0.73409951
68MAP3K30.73108155
69MAP3K10.71781175
70PRKAA10.70722064
71CAMK1G0.70698816
72PAK40.70301552
73MAPK120.69289373
74PDK20.69184863
75EPHA30.68547920
76AKT30.67799203
77ACVR1B0.66001178
78GSK3A0.65678250
79TRPM70.65543518
80PHKG20.64946651
81PHKG10.64946651
82PTK20.64596232
83MYLK0.64113709
84SGK30.62483266
85PRKCZ0.62269194
86LRRK20.62208799
87PRKACG0.59260640
88PDGFRB0.58024097
89IRAK30.57919868
90PRKD20.57896262
91PDK30.56953227
92PDK40.56953227
93STK38L0.56845336
94DAPK20.56636574
95EPHA20.56511700
96MAP3K20.56326754
97RPS6KL10.55115398
98RPS6KC10.55115398
99STK30.54858246
100MAPK70.54469656
101ARAF0.53566882
102PDPK10.50109979
103RPS6KA20.48587795
104MAP2K20.48367557
105RPS6KA60.48298956
106STK100.46999405
107NEK10.45859335
108MAP2K10.45252546
109EPHB20.44123399
110DAPK30.43574490
111NME10.42364845
112STK380.42138711
113MAP3K130.41372787
114MATK0.40694676
115MAP2K60.40669549
116TTN0.39980136
117RET0.39538423
118LATS20.39401535
119MAP3K60.39181828
120MAP3K140.38638656
121LMTK20.37563522
122PRKD10.37301895
123PDK10.36559162
124KSR20.36460082
125ILK0.35814554
126MAP3K80.35053605
127PRKCI0.34778723
128CAMK40.34035236
129FGR0.33988570
130EGFR0.33914635
131JAK30.33853846
132PIK3CA0.32084049
133FGFR10.31711394
134IGF1R0.31114477
135DDR20.30295005
136CAMK2G0.30032346
137GRK10.29644083
138IKBKE0.29339883
139PRKG20.27574131

Predicted pathways (KEGG)

RankGene SetZ-score
1Primary bile acid biosynthesis_Homo sapiens_hsa001204.29917594
2Nitrogen metabolism_Homo sapiens_hsa009103.56569018
3Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004003.33970520
4Ascorbate and aldarate metabolism_Homo sapiens_hsa000533.30513289
5Arginine biosynthesis_Homo sapiens_hsa002202.99968241
6Tryptophan metabolism_Homo sapiens_hsa003802.72781794
7Fatty acid degradation_Homo sapiens_hsa000712.68808333
8Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006302.64669478
9Other glycan degradation_Homo sapiens_hsa005112.63071955
10Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010402.61301482
11Complement and coagulation cascades_Homo sapiens_hsa046102.55604147
12Valine, leucine and isoleucine degradation_Homo sapiens_hsa002802.51999886
13Glycine, serine and threonine metabolism_Homo sapiens_hsa002602.40187282
14Pentose and glucuronate interconversions_Homo sapiens_hsa000402.23964870
15Butanoate metabolism_Homo sapiens_hsa006502.09141703
16Propanoate metabolism_Homo sapiens_hsa006402.06387716
17PPAR signaling pathway_Homo sapiens_hsa033202.04872682
18Drug metabolism - cytochrome P450_Homo sapiens_hsa009822.02900894
19Fatty acid metabolism_Homo sapiens_hsa012122.01551936
20Peroxisome_Homo sapiens_hsa041461.98451915
21Caffeine metabolism_Homo sapiens_hsa002321.94091754
22Steroid hormone biosynthesis_Homo sapiens_hsa001401.90941303
23Chemical carcinogenesis_Homo sapiens_hsa052041.87066036
24Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.86486914
252-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.82695402
26Histidine metabolism_Homo sapiens_hsa003401.79926380
27beta-Alanine metabolism_Homo sapiens_hsa004101.70578815
28Drug metabolism - other enzymes_Homo sapiens_hsa009831.68444944
29Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.64454227
30Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002501.64372470
31Retinol metabolism_Homo sapiens_hsa008301.60174135
32Staphylococcus aureus infection_Homo sapiens_hsa051501.57536815
33Bile secretion_Homo sapiens_hsa049761.56639333
34Selenocompound metabolism_Homo sapiens_hsa004501.51642885
35Phenylalanine metabolism_Homo sapiens_hsa003601.46684315
36Pyruvate metabolism_Homo sapiens_hsa006201.43030438
37Fat digestion and absorption_Homo sapiens_hsa049751.39803452
38Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.39105524
39Sulfur metabolism_Homo sapiens_hsa009201.38601200
40Tyrosine metabolism_Homo sapiens_hsa003501.37590748
41Starch and sucrose metabolism_Homo sapiens_hsa005001.32881652
42Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.26863032
43Biosynthesis of amino acids_Homo sapiens_hsa012301.26682083
44Carbon metabolism_Homo sapiens_hsa012001.26410702
45Cysteine and methionine metabolism_Homo sapiens_hsa002701.24916799
46Fatty acid elongation_Homo sapiens_hsa000621.23458379
47Folate biosynthesis_Homo sapiens_hsa007901.20579478
48ABC transporters_Homo sapiens_hsa020101.16578571
49Lysine degradation_Homo sapiens_hsa003101.02539878
50Sulfur relay system_Homo sapiens_hsa041221.00253867
51Cyanoamino acid metabolism_Homo sapiens_hsa004600.98027035
52Steroid biosynthesis_Homo sapiens_hsa001000.97741633
53Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.93965463
54Arginine and proline metabolism_Homo sapiens_hsa003300.93212474
55Lysosome_Homo sapiens_hsa041420.90817746
56Vitamin digestion and absorption_Homo sapiens_hsa049770.90522774
57Maturity onset diabetes of the young_Homo sapiens_hsa049500.86933990
58Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.86918951
59Vitamin B6 metabolism_Homo sapiens_hsa007500.85764035
60Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.83243352
61Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.82743913
62Fatty acid biosynthesis_Homo sapiens_hsa000610.81124316
63Glycerolipid metabolism_Homo sapiens_hsa005610.80036422
64Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.78127804
65Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.75784437
66Sphingolipid metabolism_Homo sapiens_hsa006000.74456252
67Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.70441507
68One carbon pool by folate_Homo sapiens_hsa006700.67150005
69Glutathione metabolism_Homo sapiens_hsa004800.64761934
70Pentose phosphate pathway_Homo sapiens_hsa000300.60895427
71Pertussis_Homo sapiens_hsa051330.54391865
72Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.51099919
73Metabolic pathways_Homo sapiens_hsa011000.40128877
74Galactose metabolism_Homo sapiens_hsa000520.38583532
75Insulin resistance_Homo sapiens_hsa049310.37518734
76Fructose and mannose metabolism_Homo sapiens_hsa000510.37370464
77Adipocytokine signaling pathway_Homo sapiens_hsa049200.33700537
78Prion diseases_Homo sapiens_hsa050200.31868062
79Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.29440567
80alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.27486365
81Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.26209594
82N-Glycan biosynthesis_Homo sapiens_hsa005100.25180441
83ECM-receptor interaction_Homo sapiens_hsa045120.20197665
84Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.19528952
85Glycerophospholipid metabolism_Homo sapiens_hsa005640.19181439
86Linoleic acid metabolism_Homo sapiens_hsa005910.17597807
87AMPK signaling pathway_Homo sapiens_hsa041520.15351173
88Glucagon signaling pathway_Homo sapiens_hsa049220.15056935
89Insulin signaling pathway_Homo sapiens_hsa049100.00436223
90Arachidonic acid metabolism_Homo sapiens_hsa00590-0.2273802
91Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141-0.1983507
92African trypanosomiasis_Homo sapiens_hsa05143-0.1971479
93Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604-0.1926988
94Thyroid hormone synthesis_Homo sapiens_hsa04918-0.1672453
95Amoebiasis_Homo sapiens_hsa05146-0.1665912
96Longevity regulating pathway - multiple species_Homo sapiens_hsa04213-0.1635586
97Protein digestion and absorption_Homo sapiens_hsa04974-0.1607087
98Mineral absorption_Homo sapiens_hsa04978-0.1589968
99Hepatitis C_Homo sapiens_hsa05160-0.1374824
100Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534-0.1363740
101Glycosaminoglycan degradation_Homo sapiens_hsa00531-0.1314561
102Bladder cancer_Homo sapiens_hsa05219-0.1258298
103Carbohydrate digestion and absorption_Homo sapiens_hsa04973-0.1221773
104Longevity regulating pathway - mammal_Homo sapiens_hsa04211-0.1213832
105Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932-0.0996922
106Terpenoid backbone biosynthesis_Homo sapiens_hsa00900-0.0834523
107Central carbon metabolism in cancer_Homo sapiens_hsa05230-0.0424979
108Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520-0.0228832
109Ovarian steroidogenesis_Homo sapiens_hsa04913-0.0174001
110Renin-angiotensin system_Homo sapiens_hsa04614-0.0164906

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