

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | sleep (GO:0030431) | 8.14710289 |
| 2 | tolerance induction (GO:0002507) | 7.57113614 |
| 3 | cellular response to interleukin-15 (GO:0071350) | 6.84466870 |
| 4 | negative regulation of cell killing (GO:0031342) | 5.35024770 |
| 5 | negative regulation of leukocyte mediated cytotoxicity (GO:0001911) | 5.35024770 |
| 6 | response to interleukin-15 (GO:0070672) | 5.33842972 |
| 7 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 5.08836984 |
| 8 | regulation of T cell mediated cytotoxicity (GO:0001914) | 4.76524566 |
| 9 | RNA destabilization (GO:0050779) | 4.61909280 |
| 10 | negative regulation of lipopolysaccharide-mediated signaling pathway (GO:0031665) | 4.50959022 |
| 11 | positive regulation of T cell mediated cytotoxicity (GO:0001916) | 4.49916572 |
| 12 | positive regulation of defense response to virus by host (GO:0002230) | 4.48537770 |
| 13 | regulation of germinal center formation (GO:0002634) | 4.43901700 |
| 14 | DNA deamination (GO:0045006) | 4.40903283 |
| 15 | response to gravity (GO:0009629) | 4.40123611 |
| 16 | negative thymic T cell selection (GO:0045060) | 4.29758604 |
| 17 | regulation of memory T cell differentiation (GO:0043380) | 4.28531184 |
| 18 | mast cell activation (GO:0045576) | 4.27225570 |
| 19 | response to muramyl dipeptide (GO:0032495) | 4.26065337 |
| 20 | negative T cell selection (GO:0043383) | 4.25247776 |
| 21 | mast cell degranulation (GO:0043303) | 4.23111696 |
| 22 | mast cell activation involved in immune response (GO:0002279) | 4.23111696 |
| 23 | regulation of defense response to virus by host (GO:0050691) | 4.15592804 |
| 24 | T-helper cell differentiation (GO:0042093) | 3.81789412 |
| 25 | CD4-positive, alpha-beta T cell differentiation involved in immune response (GO:0002294) | 3.81789412 |
| 26 | regulation of leukocyte mediated cytotoxicity (GO:0001910) | 3.79424291 |
| 27 | negative regulation of interleukin-1 beta production (GO:0032691) | 3.79038878 |
| 28 | positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) | 3.69226031 |
| 29 | regulation of B cell receptor signaling pathway (GO:0050855) | 3.67753939 |
| 30 | adenosine metabolic process (GO:0046085) | 3.64850793 |
| 31 | positive regulation of T-helper 1 type immune response (GO:0002827) | 3.63943324 |
| 32 | Arp2/3 complex-mediated actin nucleation (GO:0034314) | 3.63404144 |
| 33 | regulation of gamma-delta T cell differentiation (GO:0045586) | 3.63363895 |
| 34 | negative regulation of transcription elongation from RNA polymerase II promoter (GO:0034244) | 3.58279685 |
| 35 | negative regulation of interleukin-1 production (GO:0032692) | 3.56927015 |
| 36 | tumor necrosis factor-mediated signaling pathway (GO:0033209) | 3.56318210 |
| 37 | regulation of chronic inflammatory response (GO:0002676) | 3.54160872 |
| 38 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 3.54142606 |
| 39 | alpha-beta T cell differentiation involved in immune response (GO:0002293) | 3.52050297 |
| 40 | alpha-beta T cell activation involved in immune response (GO:0002287) | 3.52050297 |
| 41 | T cell differentiation involved in immune response (GO:0002292) | 3.52050297 |
| 42 | positive regulation of T cell mediated immunity (GO:0002711) | 3.51678371 |
| 43 | regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay (GO:1900151) | 3.50872137 |
| 44 | positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay (GO | 3.50872137 |
| 45 | negative regulation of bone resorption (GO:0045779) | 3.50845317 |
| 46 | regulation of T cell receptor signaling pathway (GO:0050856) | 3.50177192 |
| 47 | positive regulation of osteoclast differentiation (GO:0045672) | 3.46563740 |
| 48 | positive regulation of leukocyte mediated cytotoxicity (GO:0001912) | 3.43747030 |
| 49 | actin nucleation (GO:0045010) | 3.42811274 |
| 50 | protein K11-linked deubiquitination (GO:0035871) | 3.41544227 |
| 51 | germ cell migration (GO:0008354) | 3.40826220 |
| 52 | negative regulation of antigen receptor-mediated signaling pathway (GO:0050858) | 3.40051052 |
| 53 | regulation of cell killing (GO:0031341) | 3.39981961 |
| 54 | positive regulation of alpha-beta T cell proliferation (GO:0046641) | 3.34011156 |
| 55 | regulation of antigen receptor-mediated signaling pathway (GO:0050854) | 3.29259944 |
| 56 | regulation of T cell mediated immunity (GO:0002709) | 3.24226923 |
| 57 | positive thymic T cell selection (GO:0045059) | 3.21529260 |
| 58 | negative regulation of T cell receptor signaling pathway (GO:0050860) | 3.20900165 |
| 59 | positive regulation of mRNA catabolic process (GO:0061014) | 3.19900351 |
| 60 | regulation of T-helper 1 type immune response (GO:0002825) | 3.19193522 |
| 61 | antigen processing and presentation of endogenous peptide antigen (GO:0002483) | 3.15228028 |
| 62 | cellular response to exogenous dsRNA (GO:0071360) | 3.14500845 |
| 63 | cytidine deamination (GO:0009972) | 3.12514830 |
| 64 | cytidine metabolic process (GO:0046087) | 3.12514830 |
| 65 | cytidine catabolic process (GO:0006216) | 3.12514830 |
| 66 | lymph node development (GO:0048535) | 3.11038002 |
| 67 | positive regulation of cell killing (GO:0031343) | 3.07163345 |
| 68 | negative regulation of T cell mediated immunity (GO:0002710) | 3.06272630 |
| 69 | negative regulation of bone remodeling (GO:0046851) | 3.05940975 |
| 70 | leukocyte degranulation (GO:0043299) | 3.05211481 |
| 71 | regulation of gamma-delta T cell activation (GO:0046643) | 3.04220568 |
| 72 | alpha-beta T cell differentiation (GO:0046632) | 3.03208955 |
| 73 | preassembly of GPI anchor in ER membrane (GO:0016254) | 3.01110826 |
| 74 | regulation of alpha-beta T cell proliferation (GO:0046640) | 3.00688811 |
| 75 | negative regulation of T cell apoptotic process (GO:0070233) | 3.00467094 |
| 76 | positive regulation of prostaglandin secretion (GO:0032308) | 2.99764136 |
| 77 | positive regulation of tyrosine phosphorylation of Stat5 protein (GO:0042523) | 2.98420723 |
| 78 | lysosome localization (GO:0032418) | 2.95679514 |
| 79 | mitotic cell cycle arrest (GO:0071850) | 2.95079056 |
| 80 | positive regulation of T cell differentiation in thymus (GO:0033089) | 2.94081749 |
| 81 | natural killer cell activation (GO:0030101) | 2.93906396 |
| 82 | negative regulation of toll-like receptor 4 signaling pathway (GO:0034144) | 2.93473859 |
| 83 | regulation of activation of Janus kinase activity (GO:0010533) | 2.91573130 |
| 84 | negative regulation of DNA-templated transcription, elongation (GO:0032785) | 2.90115827 |
| 85 | regulation of regulatory T cell differentiation (GO:0045589) | 2.88966436 |
| 86 | positive regulation of T cell cytokine production (GO:0002726) | 2.88261555 |
| 87 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 2.87715408 |
| 88 | regulation of antigen processing and presentation of peptide antigen (GO:0002583) | 2.87038004 |
| 89 | regulation of nuclear-transcribed mRNA poly(A) tail shortening (GO:0060211) | 2.87019377 |
| 90 | positive regulation of nuclear-transcribed mRNA poly(A) tail shortening (GO:0060213) | 2.87019377 |
| 91 | natural killer cell activation involved in immune response (GO:0002323) | 2.86404935 |
| 92 | regulation of interleukin-8 secretion (GO:2000482) | 2.85365561 |
| 93 | antigen processing and presentation via MHC class Ib (GO:0002475) | 2.84157407 |
| 94 | endoderm formation (GO:0001706) | 2.83701357 |
| 95 | positive regulation of gamma-delta T cell activation (GO:0046645) | 2.83306518 |
| 96 | T cell differentiation (GO:0030217) | 2.81755262 |
| 97 | negative regulation of innate immune response (GO:0045824) | 2.81647474 |
| 98 | regulation of fibroblast apoptotic process (GO:2000269) | 2.80160079 |
| 99 | regulation of mitotic spindle checkpoint (GO:1903504) | 2.78146686 |
| 100 | regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266) | 2.78146686 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 5.76551173 |
| 2 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 5.33454913 |
| 3 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 5.16760858 |
| 4 | RUNX_20019798_ChIP-Seq_JUKART_Human | 3.92565895 |
| 5 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 3.29385897 |
| 6 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 2.98845608 |
| 7 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 2.96814646 |
| 8 | MYB_26560356_Chip-Seq_TH2_Human | 2.95831619 |
| 9 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.70235734 |
| 10 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 2.69854464 |
| 11 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 2.69670582 |
| 12 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 2.58309296 |
| 13 | GATA3_26560356_Chip-Seq_TH2_Human | 2.54156924 |
| 14 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 2.53162240 |
| 15 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 2.50971265 |
| 16 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 2.35423660 |
| 17 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 2.28149320 |
| 18 | GATA3_27048872_Chip-Seq_THYMUS_Human | 2.08584289 |
| 19 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 2.06158732 |
| 20 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 2.03113443 |
| 21 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.97184702 |
| 22 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 1.85508776 |
| 23 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 1.83107032 |
| 24 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.75954284 |
| 25 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.74374157 |
| 26 | MYB_26560356_Chip-Seq_TH1_Human | 1.74336955 |
| 27 | GATA2_20887958_ChIP-Seq_HPC-7_Mouse | 1.69846337 |
| 28 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 1.69252728 |
| 29 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 1.67076346 |
| 30 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.64815128 |
| 31 | LMO2_20887958_ChIP-Seq_HPC-7_Mouse | 1.63085530 |
| 32 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 1.61813005 |
| 33 | MAF_26560356_Chip-Seq_TH1_Human | 1.51828954 |
| 34 | UTX_26944678_Chip-Seq_JUKART_Human | 1.49851053 |
| 35 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.42184901 |
| 36 | SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 1.38014432 |
| 37 | RUNX1_17652178_ChIP-ChIP_JURKAT_Human | 1.35858971 |
| 38 | SPI1_23547873_ChIP-Seq_NB4_Human | 1.35473704 |
| 39 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 1.33830827 |
| 40 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.33660805 |
| 41 | BCL6_27268052_Chip-Seq_Bcells_Human | 1.29771467 |
| 42 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 1.27590744 |
| 43 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 1.26739905 |
| 44 | TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.25455837 |
| 45 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.22427112 |
| 46 | GATA3_26560356_Chip-Seq_TH1_Human | 1.21945624 |
| 47 | MAF_26560356_Chip-Seq_TH2_Human | 1.21945490 |
| 48 | GATA2_21666600_ChIP-Seq_HMVEC_Human | 1.20900143 |
| 49 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 1.20639980 |
| 50 | RUNX1_22412390_ChIP-Seq_EML_Mouse | 1.20475187 |
| 51 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 1.20359449 |
| 52 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.20313738 |
| 53 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.19446397 |
| 54 | RUNX1_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.19128482 |
| 55 | AR_20517297_ChIP-Seq_VCAP_Human | 1.17346328 |
| 56 | STAT1_20625510_ChIP-Seq_HELA_Human | 1.17248727 |
| 57 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.16459700 |
| 58 | FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.15889223 |
| 59 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.15636535 |
| 60 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 1.14552653 |
| 61 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 1.13639669 |
| 62 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 1.13501890 |
| 63 | CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 1.10744068 |
| 64 | VDR_22108803_ChIP-Seq_LS180_Human | 1.10711120 |
| 65 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.08935870 |
| 66 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.08815650 |
| 67 | JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 1.07224116 |
| 68 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.06006665 |
| 69 | ESR1_21235772_ChIP-Seq_MCF-7_Human | 1.05978752 |
| 70 | SCL_19346495_ChIP-Seq_HPC-7_Human | 1.05139698 |
| 71 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.03959530 |
| 72 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.03522833 |
| 73 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 1.03053530 |
| 74 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.01901362 |
| 75 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 1.01596568 |
| 76 | JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 1.01443354 |
| 77 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 0.99555509 |
| 78 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 0.99555509 |
| 79 | P300_27268052_Chip-Seq_Bcells_Human | 0.97077998 |
| 80 | GATA2_22383799_ChIP-Seq_G1ME_Mouse | 0.96724494 |
| 81 | HOXB7_26014856_ChIP-Seq_BT474_Human | 0.95839742 |
| 82 | NANOG_20526341_ChIP-Seq_ESCs_Human | 0.95612651 |
| 83 | STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse | 0.95089343 |
| 84 | CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human | 0.94831378 |
| 85 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 0.93161964 |
| 86 | PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 0.92980361 |
| 87 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 0.92229208 |
| 88 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 0.91573877 |
| 89 | GATA1_22025678_ChIP-Seq_K562_Human | 0.91404522 |
| 90 | SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 0.87644525 |
| 91 | BCOR_27268052_Chip-Seq_Bcells_Human | 0.87009366 |
| 92 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 0.86997965 |
| 93 | MYC_18940864_ChIP-ChIP_HL60_Human | 0.85617558 |
| 94 | CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse | 0.85616725 |
| 95 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 0.84245568 |
| 96 | ELF1_20517297_ChIP-Seq_JURKAT_Human | 0.83966079 |
| 97 | ERA_21632823_ChIP-Seq_H3396_Human | 0.83798099 |
| 98 | NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 0.83634912 |
| 99 | PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse | 0.83462571 |
| 100 | MYC_19829295_ChIP-Seq_ESCs_Human | 0.80822815 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0005671_abnormal_response_to | 4.77659721 |
| 2 | MP0003724_increased_susceptibility_to | 4.48107322 |
| 3 | MP0003436_decreased_susceptibility_to | 4.03184063 |
| 4 | MP0002009_preneoplasia | 3.55540035 |
| 5 | MP0000465_gastrointestinal_hemorrhage | 3.23205491 |
| 6 | MP0002166_altered_tumor_susceptibility | 3.22821288 |
| 7 | MP0003763_abnormal_thymus_physiology | 3.13732605 |
| 8 | MP0005000_abnormal_immune_tolerance | 3.05499845 |
| 9 | MP0002933_joint_inflammation | 3.04610856 |
| 10 | MP0000685_abnormal_immune_system | 2.97762931 |
| 11 | MP0001835_abnormal_antigen_presentation | 2.96053880 |
| 12 | MP0006072_abnormal_retinal_apoptosis | 2.48091575 |
| 13 | MP0002006_tumorigenesis | 2.47908799 |
| 14 | MP0002723_abnormal_immune_serum | 2.44361700 |
| 15 | MP0009785_altered_susceptibility_to | 2.37730434 |
| 16 | MP0001533_abnormal_skeleton_physiology | 2.37213652 |
| 17 | MP0001800_abnormal_humoral_immune | 2.37007355 |
| 18 | MP0002148_abnormal_hypersensitivity_rea | 2.18184333 |
| 19 | MP0001819_abnormal_immune_cell | 2.17521649 |
| 20 | MP0002420_abnormal_adaptive_immunity | 2.12386574 |
| 21 | MP0002452_abnormal_antigen_presenting | 2.11593324 |
| 22 | MP0004947_skin_inflammation | 2.00111413 |
| 23 | MP0002419_abnormal_innate_immunity | 1.92434259 |
| 24 | MP0001853_heart_inflammation | 1.85690665 |
| 25 | MP0002405_respiratory_system_inflammati | 1.84211775 |
| 26 | MP0001790_abnormal_immune_system | 1.81797604 |
| 27 | MP0005387_immune_system_phenotype | 1.81797604 |
| 28 | MP0005025_abnormal_response_to | 1.79864778 |
| 29 | MP0001501_abnormal_sleep_pattern | 1.79813561 |
| 30 | MP0005075_abnormal_melanosome_morpholog | 1.61204559 |
| 31 | MP0002876_abnormal_thyroid_physiology | 1.59056558 |
| 32 | MP0000716_abnormal_immune_system | 1.57313974 |
| 33 | MP0005360_urolithiasis | 1.54952355 |
| 34 | MP0009764_decreased_sensitivity_to | 1.52867075 |
| 35 | MP0002398_abnormal_bone_marrow | 1.52403026 |
| 36 | MP0000689_abnormal_spleen_morphology | 1.49475189 |
| 37 | MP0001845_abnormal_inflammatory_respons | 1.46839688 |
| 38 | MP0010155_abnormal_intestine_physiology | 1.42613476 |
| 39 | MP0002722_abnormal_immune_system | 1.39817536 |
| 40 | MP0009333_abnormal_splenocyte_physiolog | 1.37250591 |
| 41 | MP0003866_abnormal_defecation | 1.35383011 |
| 42 | MP0005390_skeleton_phenotype | 1.35246510 |
| 43 | MP0000703_abnormal_thymus_morphology | 1.34450636 |
| 44 | MP0002102_abnormal_ear_morphology | 1.30221693 |
| 45 | MP0005365_abnormal_bile_salt | 1.26552752 |
| 46 | MP0002429_abnormal_blood_cell | 1.21103648 |
| 47 | MP0002254_reproductive_system_inflammat | 1.15774142 |
| 48 | MP0000858_altered_metastatic_potential | 1.14165609 |
| 49 | MP0003195_calcinosis | 1.14093900 |
| 50 | MP0002998_abnormal_bone_remodeling | 1.12075835 |
| 51 | MP0003828_pulmonary_edema | 1.11438969 |
| 52 | MP0008877_abnormal_DNA_methylation | 1.11339095 |
| 53 | MP0008875_abnormal_xenobiotic_pharmacok | 1.09777971 |
| 54 | MP0004147_increased_porphyrin_level | 1.09216003 |
| 55 | MP0010386_abnormal_urinary_bladder | 1.06632221 |
| 56 | MP0001919_abnormal_reproductive_system | 1.02894280 |
| 57 | MP0005253_abnormal_eye_physiology | 1.01258215 |
| 58 | MP0001542_abnormal_bone_strength | 1.01055857 |
| 59 | MP0003656_abnormal_erythrocyte_physiolo | 0.99686688 |
| 60 | MP0001879_abnormal_lymphatic_vessel | 0.96948947 |
| 61 | MP0001765_abnormal_ion_homeostasis | 0.96903367 |
| 62 | MP0001243_abnormal_dermal_layer | 0.95904474 |
| 63 | MP0001851_eye_inflammation | 0.95597320 |
| 64 | MP0002138_abnormal_hepatobiliary_system | 0.94766103 |
| 65 | MP0001986_abnormal_taste_sensitivity | 0.94188061 |
| 66 | MP0001873_stomach_inflammation | 0.93552064 |
| 67 | MP0003950_abnormal_plasma_membrane | 0.90393597 |
| 68 | MP0003011_delayed_dark_adaptation | 0.89658916 |
| 69 | MP0008872_abnormal_physiological_respon | 0.88645929 |
| 70 | MP0008469_abnormal_protein_level | 0.87858252 |
| 71 | MP0005464_abnormal_platelet_physiology | 0.87855275 |
| 72 | MP0003638_abnormal_response/metabolism_ | 0.87624598 |
| 73 | MP0003795_abnormal_bone_structure | 0.86867345 |
| 74 | MP0008961_abnormal_basal_metabolism | 0.86853774 |
| 75 | MP0008775_abnormal_heart_ventricle | 0.84886712 |
| 76 | MP0009763_increased_sensitivity_to | 0.84463798 |
| 77 | MP0003045_fibrosis | 0.83263447 |
| 78 | MP0006082_CNS_inflammation | 0.79875194 |
| 79 | MP0000372_irregular_coat_pigmentation | 0.79182128 |
| 80 | MP0003878_abnormal_ear_physiology | 0.79032624 |
| 81 | MP0005377_hearing/vestibular/ear_phenot | 0.79032624 |
| 82 | MP0005084_abnormal_gallbladder_morpholo | 0.78155396 |
| 83 | MP0004885_abnormal_endolymph | 0.76839533 |
| 84 | MP0005389_reproductive_system_phenotype | 0.76026316 |
| 85 | MP0005551_abnormal_eye_electrophysiolog | 0.73766508 |
| 86 | MP0010329_abnormal_lipoprotein_level | 0.73629414 |
| 87 | MP0000013_abnormal_adipose_tissue | 0.70144022 |
| 88 | MP0003191_abnormal_cellular_cholesterol | 0.66902287 |
| 89 | MP0003252_abnormal_bile_duct | 0.66725887 |
| 90 | MP0000249_abnormal_blood_vessel | 0.66686487 |
| 91 | MP0010368_abnormal_lymphatic_system | 0.66617308 |
| 92 | MP0001958_emphysema | 0.66122836 |
| 93 | MP0009840_abnormal_foam_cell | 0.65723633 |
| 94 | MP0003279_aneurysm | 0.65540626 |
| 95 | MP0002136_abnormal_kidney_physiology | 0.65106517 |
| 96 | MP0009780_abnormal_chondrocyte_physiolo | 0.64481562 |
| 97 | MP0006054_spinal_hemorrhage | 0.63232652 |
| 98 | MP0005165_increased_susceptibility_to | 0.62632901 |
| 99 | MP0003879_abnormal_hair_cell | 0.61881657 |
| 100 | MP0002736_abnormal_nociception_after | 0.61279665 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | IgG deficiency (HP:0004315) | 6.52725534 |
| 2 | Severe combined immunodeficiency (HP:0004430) | 5.85431164 |
| 3 | Elevated erythrocyte sedimentation rate (HP:0003565) | 4.80416910 |
| 4 | T lymphocytopenia (HP:0005403) | 4.69365075 |
| 5 | Combined immunodeficiency (HP:0005387) | 4.57886125 |
| 6 | Stomach cancer (HP:0012126) | 4.51591497 |
| 7 | Abnormality of eosinophils (HP:0001879) | 4.42371891 |
| 8 | Abnormality of T cell number (HP:0011839) | 4.40033198 |
| 9 | Stomatitis (HP:0010280) | 4.34314930 |
| 10 | Prostate neoplasm (HP:0100787) | 3.94262605 |
| 11 | Myositis (HP:0100614) | 3.88790668 |
| 12 | Conical tooth (HP:0000698) | 3.86109447 |
| 13 | Pustule (HP:0200039) | 3.77416159 |
| 14 | Thyroiditis (HP:0100646) | 3.66932833 |
| 15 | Abnormality of T cells (HP:0002843) | 3.62174172 |
| 16 | Anhidrosis (HP:0000970) | 3.47538020 |
| 17 | Renal cortical cysts (HP:0000803) | 3.38909374 |
| 18 | Abnormality of the prostate (HP:0008775) | 3.28303186 |
| 19 | Eosinophilia (HP:0001880) | 3.10662555 |
| 20 | Leukocytosis (HP:0001974) | 3.00001740 |
| 21 | Abnormality of T cell physiology (HP:0011840) | 2.94127452 |
| 22 | Abnormality of B cell number (HP:0010975) | 2.87833508 |
| 23 | Retrobulbar optic neuritis (HP:0100654) | 2.84569229 |
| 24 | Optic neuritis (HP:0100653) | 2.84569229 |
| 25 | Granulocytopenia (HP:0001913) | 2.83638433 |
| 26 | Panhypogammaglobulinemia (HP:0003139) | 2.71631136 |
| 27 | Brittle hair (HP:0002299) | 2.65855131 |
| 28 | Pulmonary infiltrates (HP:0002113) | 2.63320098 |
| 29 | B lymphocytopenia (HP:0010976) | 2.61745613 |
| 30 | Abnormality of the pons (HP:0007361) | 2.59818302 |
| 31 | Recurrent fungal infections (HP:0002841) | 2.58982137 |
| 32 | Recurrent bronchitis (HP:0002837) | 2.58718979 |
| 33 | Pulmonary fibrosis (HP:0002206) | 2.58212824 |
| 34 | Eczematoid dermatitis (HP:0000976) | 2.54470583 |
| 35 | Hypoplasia of the pons (HP:0012110) | 2.52455841 |
| 36 | Orchitis (HP:0100796) | 2.51391791 |
| 37 | Joint swelling (HP:0001386) | 2.49831902 |
| 38 | Type II lissencephaly (HP:0007260) | 2.47526558 |
| 39 | Congenital, generalized hypertrichosis (HP:0004540) | 2.44992602 |
| 40 | Congenital stationary night blindness (HP:0007642) | 2.44254582 |
| 41 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 2.38798797 |
| 42 | Abnormal protein N-linked glycosylation (HP:0012347) | 2.38798797 |
| 43 | Abnormal protein glycosylation (HP:0012346) | 2.38798797 |
| 44 | Abnormal glycosylation (HP:0012345) | 2.38798797 |
| 45 | Abnormality of the renal cortex (HP:0011035) | 2.35445447 |
| 46 | IgA deficiency (HP:0002720) | 2.28124212 |
| 47 | Facial diplegia (HP:0001349) | 2.26831804 |
| 48 | Pancreatitis (HP:0001733) | 2.24563463 |
| 49 | Hypoplasia of the uterus (HP:0000013) | 2.22889282 |
| 50 | Type I transferrin isoform profile (HP:0003642) | 2.21357870 |
| 51 | Alveolar cell carcinoma (HP:0006519) | 2.18390102 |
| 52 | Abolished electroretinogram (ERG) (HP:0000550) | 2.17675062 |
| 53 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 2.17532178 |
| 54 | Increased IgM level (HP:0003496) | 2.14250088 |
| 55 | IgM deficiency (HP:0002850) | 2.12211370 |
| 56 | Chronic diarrhea (HP:0002028) | 2.11412047 |
| 57 | Growth hormone excess (HP:0000845) | 2.08950037 |
| 58 | Vasculitis (HP:0002633) | 2.08272523 |
| 59 | Aplasia/hypoplasia of the uterus (HP:0008684) | 2.06636275 |
| 60 | Abnormality of male internal genitalia (HP:0000022) | 2.03298266 |
| 61 | Hypoproteinemia (HP:0003075) | 2.03290934 |
| 62 | Recurrent cutaneous fungal infections (HP:0011370) | 2.01188086 |
| 63 | Chronic mucocutaneous candidiasis (HP:0002728) | 2.01188086 |
| 64 | Neutropenia (HP:0001875) | 2.00492390 |
| 65 | Progressive microcephaly (HP:0000253) | 1.98493843 |
| 66 | Persistence of primary teeth (HP:0006335) | 1.98458547 |
| 67 | Keratoconjunctivitis (HP:0001096) | 1.98292253 |
| 68 | Hydroxyprolinuria (HP:0003080) | 1.98082440 |
| 69 | Abnormality of proline metabolism (HP:0010907) | 1.98082440 |
| 70 | Mediastinal lymphadenopathy (HP:0100721) | 1.95318421 |
| 71 | Gastrointestinal stroma tumor (HP:0100723) | 1.95070894 |
| 72 | Clumsiness (HP:0002312) | 1.94200090 |
| 73 | Dysostosis multiplex (HP:0000943) | 1.92061046 |
| 74 | Opisthotonus (HP:0002179) | 1.91178934 |
| 75 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 1.90136005 |
| 76 | Abnormality of dental color (HP:0011073) | 1.87564933 |
| 77 | Bronchitis (HP:0012387) | 1.85008019 |
| 78 | Hypergammaglobulinemia (HP:0010702) | 1.83204890 |
| 79 | Lymphopenia (HP:0001888) | 1.80313752 |
| 80 | Neoplasm of the tracheobronchial system (HP:0100552) | 1.79413746 |
| 81 | Neoplasm of head and neck (HP:0012288) | 1.79365120 |
| 82 | Esophageal neoplasm (HP:0100751) | 1.79365120 |
| 83 | Hypotrichosis (HP:0001006) | 1.79253150 |
| 84 | Glomerulopathy (HP:0100820) | 1.79084833 |
| 85 | Abnormality of glutamine family amino acid metabolism (HP:0010902) | 1.78699520 |
| 86 | Attenuation of retinal blood vessels (HP:0007843) | 1.78675822 |
| 87 | Progressive inability to walk (HP:0002505) | 1.74435777 |
| 88 | Recurrent sinusitis (HP:0011108) | 1.73675527 |
| 89 | Reduced antithrombin III activity (HP:0001976) | 1.73592353 |
| 90 | Hemoptysis (HP:0002105) | 1.73258431 |
| 91 | Gastrointestinal infarctions (HP:0005244) | 1.71871560 |
| 92 | Inability to walk (HP:0002540) | 1.71658130 |
| 93 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 1.71543438 |
| 94 | 3-Methylglutaconic aciduria (HP:0003535) | 1.70267107 |
| 95 | Keratitis (HP:0000491) | 1.69898356 |
| 96 | Abnormal rod and cone electroretinograms (HP:0008323) | 1.69718546 |
| 97 | Hyperglycinuria (HP:0003108) | 1.69518310 |
| 98 | Hematochezia (HP:0002573) | 1.68028591 |
| 99 | Thyroid-stimulating hormone excess (HP:0002925) | 1.66677987 |
| 100 | Abnormality of cells of the lymphoid lineage (HP:0012140) | 1.66351673 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | TAOK3 | 5.57816283 |
| 2 | TXK | 4.44186891 |
| 3 | GRK6 | 4.34318368 |
| 4 | MAP3K14 | 3.68968838 |
| 5 | MAP2K2 | 3.41437957 |
| 6 | TLK1 | 2.89189005 |
| 7 | TESK2 | 2.82751780 |
| 8 | JAK1 | 2.62013611 |
| 9 | TBK1 | 2.60023555 |
| 10 | ZAK | 2.57606120 |
| 11 | IKBKE | 2.42470964 |
| 12 | MAPKAPK3 | 2.40111110 |
| 13 | IKBKB | 2.31952521 |
| 14 | MAP4K1 | 2.17193646 |
| 15 | FES | 1.95422341 |
| 16 | ZAP70 | 1.81239025 |
| 17 | EPHA3 | 1.80912003 |
| 18 | MUSK | 1.75431144 |
| 19 | KIT | 1.72116802 |
| 20 | MATK | 1.57675465 |
| 21 | KDR | 1.50093707 |
| 22 | NUAK1 | 1.49936300 |
| 23 | BMPR2 | 1.46677920 |
| 24 | CAMKK2 | 1.46622614 |
| 25 | LIMK1 | 1.43406317 |
| 26 | MST4 | 1.37231637 |
| 27 | MYLK | 1.36574613 |
| 28 | ADRBK2 | 1.29760141 |
| 29 | MAP4K2 | 1.20599917 |
| 30 | SYK | 1.14636834 |
| 31 | GRK1 | 1.13744913 |
| 32 | EIF2AK2 | 1.07343377 |
| 33 | MAPK7 | 1.06683028 |
| 34 | LCK | 1.01418368 |
| 35 | CSF1R | 1.00968870 |
| 36 | TESK1 | 0.98400567 |
| 37 | PIM1 | 0.93978989 |
| 38 | VRK2 | 0.92973855 |
| 39 | WNK4 | 0.92005689 |
| 40 | ITK | 0.89980270 |
| 41 | BCKDK | 0.89457503 |
| 42 | JAK3 | 0.84591149 |
| 43 | PINK1 | 0.81962568 |
| 44 | BTK | 0.81547312 |
| 45 | TEC | 0.80138698 |
| 46 | LYN | 0.79724542 |
| 47 | DAPK1 | 0.75955557 |
| 48 | RPS6KA2 | 0.74135373 |
| 49 | CHUK | 0.72586965 |
| 50 | TRPM7 | 0.69380416 |
| 51 | SIK3 | 0.64307293 |
| 52 | PRKCQ | 0.64129506 |
| 53 | MAPKAPK2 | 0.62133390 |
| 54 | CDK4 | 0.60793357 |
| 55 | TYK2 | 0.60206586 |
| 56 | IGF1R | 0.60100311 |
| 57 | NTRK1 | 0.59669548 |
| 58 | PRKD2 | 0.59474963 |
| 59 | ERBB3 | 0.58800711 |
| 60 | PHKG2 | 0.58611884 |
| 61 | PHKG1 | 0.58611884 |
| 62 | MAPK4 | 0.56068893 |
| 63 | PIK3CG | 0.53164098 |
| 64 | HCK | 0.52594134 |
| 65 | MARK3 | 0.47893216 |
| 66 | CSK | 0.47125237 |
| 67 | VRK1 | 0.46868689 |
| 68 | OXSR1 | 0.46665835 |
| 69 | TRIM28 | 0.46625125 |
| 70 | PTK2B | 0.46254219 |
| 71 | STK39 | 0.46184232 |
| 72 | ABL1 | 0.46098881 |
| 73 | INSR | 0.45886166 |
| 74 | RPS6KA6 | 0.45799847 |
| 75 | MAPK11 | 0.44922964 |
| 76 | FLT3 | 0.43292313 |
| 77 | TIE1 | 0.39498078 |
| 78 | RPS6KC1 | 0.38427416 |
| 79 | RPS6KL1 | 0.38427416 |
| 80 | EPHB1 | 0.37979256 |
| 81 | CDK19 | 0.37424184 |
| 82 | MAP2K1 | 0.35441276 |
| 83 | MAP2K7 | 0.32961660 |
| 84 | MAPK3 | 0.31998735 |
| 85 | IRAK1 | 0.31736228 |
| 86 | NEK6 | 0.31684596 |
| 87 | PRKCD | 0.31658920 |
| 88 | FGFR4 | 0.29325471 |
| 89 | MAPK13 | 0.28490372 |
| 90 | MAP3K4 | 0.27438499 |
| 91 | GRK5 | 0.26824750 |
| 92 | MAP3K12 | 0.25306171 |
| 93 | RPS6KA1 | 0.22331807 |
| 94 | MAP2K6 | 0.21788923 |
| 95 | RPS6KA5 | 0.20341286 |
| 96 | FYN | 0.20240747 |
| 97 | BLK | 0.19394075 |
| 98 | FRK | 0.19002615 |
| 99 | SIK2 | 0.18841685 |
| 100 | CSNK1D | 0.18499817 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Primary immunodeficiency_Homo sapiens_hsa05340 | 4.55111034 |
| 2 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 3.47864816 |
| 3 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 3.06365338 |
| 4 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 2.97224739 |
| 5 | Graft-versus-host disease_Homo sapiens_hsa05332 | 2.93554081 |
| 6 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 2.82877995 |
| 7 | Allograft rejection_Homo sapiens_hsa05330 | 2.60642160 |
| 8 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 2.39321527 |
| 9 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 2.38338137 |
| 10 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 2.23570589 |
| 11 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 2.21718165 |
| 12 | Asthma_Homo sapiens_hsa05310 | 2.16370331 |
| 13 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 2.15478773 |
| 14 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 2.12794864 |
| 15 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 2.02636668 |
| 16 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 1.97475770 |
| 17 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.95625051 |
| 18 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 1.85206503 |
| 19 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 1.80755761 |
| 20 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.80034949 |
| 21 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.78868896 |
| 22 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.61558967 |
| 23 | TNF signaling pathway_Homo sapiens_hsa04668 | 1.60631059 |
| 24 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.37609398 |
| 25 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 1.37011809 |
| 26 | Proteasome_Homo sapiens_hsa03050 | 1.33199547 |
| 27 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 1.30739789 |
| 28 | Regulation of autophagy_Homo sapiens_hsa04140 | 1.28795259 |
| 29 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 1.27422678 |
| 30 | Sulfur metabolism_Homo sapiens_hsa00920 | 1.25379690 |
| 31 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.23503748 |
| 32 | Leishmaniasis_Homo sapiens_hsa05140 | 1.19642989 |
| 33 | Measles_Homo sapiens_hsa05162 | 1.18860148 |
| 34 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 1.16294308 |
| 35 | Herpes simplex infection_Homo sapiens_hsa05168 | 1.14445012 |
| 36 | Tryptophan metabolism_Homo sapiens_hsa00380 | 1.08407739 |
| 37 | Malaria_Homo sapiens_hsa05144 | 1.08394641 |
| 38 | Phototransduction_Homo sapiens_hsa04744 | 1.08269738 |
| 39 | Selenocompound metabolism_Homo sapiens_hsa00450 | 1.07021502 |
| 40 | Viral myocarditis_Homo sapiens_hsa05416 | 1.04214729 |
| 41 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.04203504 |
| 42 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.03826471 |
| 43 | Shigellosis_Homo sapiens_hsa05131 | 1.03359631 |
| 44 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.03007834 |
| 45 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 1.00691984 |
| 46 | Protein export_Homo sapiens_hsa03060 | 1.00239800 |
| 47 | Osteoclast differentiation_Homo sapiens_hsa04380 | 0.95161137 |
| 48 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.91354237 |
| 49 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.85831546 |
| 50 | Apoptosis_Homo sapiens_hsa04210 | 0.83331006 |
| 51 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.82622246 |
| 52 | RNA polymerase_Homo sapiens_hsa03020 | 0.80835429 |
| 53 | Pertussis_Homo sapiens_hsa05133 | 0.79382049 |
| 54 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.78050600 |
| 55 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.75971760 |
| 56 | Other glycan degradation_Homo sapiens_hsa00511 | 0.72165026 |
| 57 | Lysosome_Homo sapiens_hsa04142 | 0.71208262 |
| 58 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 0.68789080 |
| 59 | Legionellosis_Homo sapiens_hsa05134 | 0.68084286 |
| 60 | Toxoplasmosis_Homo sapiens_hsa05145 | 0.65467840 |
| 61 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.63231319 |
| 62 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.61510675 |
| 63 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.59704104 |
| 64 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.56424263 |
| 65 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 0.55339605 |
| 66 | Peroxisome_Homo sapiens_hsa04146 | 0.54870142 |
| 67 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 0.54030112 |
| 68 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.52933022 |
| 69 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.51560617 |
| 70 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.49077535 |
| 71 | RNA degradation_Homo sapiens_hsa03018 | 0.49006395 |
| 72 | Taste transduction_Homo sapiens_hsa04742 | 0.48767524 |
| 73 | Basal transcription factors_Homo sapiens_hsa03022 | 0.46543820 |
| 74 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.43565586 |
| 75 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.42627342 |
| 76 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.41861822 |
| 77 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.41755406 |
| 78 | Sulfur relay system_Homo sapiens_hsa04122 | 0.35805139 |
| 79 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.34736631 |
| 80 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.34698076 |
| 81 | Tuberculosis_Homo sapiens_hsa05152 | 0.34471341 |
| 82 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.30820680 |
| 83 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.30637674 |
| 84 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.30636202 |
| 85 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 0.30178519 |
| 86 | Salivary secretion_Homo sapiens_hsa04970 | 0.28935127 |
| 87 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.28860150 |
| 88 | Olfactory transduction_Homo sapiens_hsa04740 | 0.25787170 |
| 89 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.25315429 |
| 90 | Influenza A_Homo sapiens_hsa05164 | 0.24627838 |
| 91 | Base excision repair_Homo sapiens_hsa03410 | 0.24449415 |
| 92 | Circadian rhythm_Homo sapiens_hsa04710 | 0.24052702 |
| 93 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.22941736 |
| 94 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.22439044 |
| 95 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.22370634 |
| 96 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.22191579 |
| 97 | Morphine addiction_Homo sapiens_hsa05032 | 0.19769641 |
| 98 | HTLV-I infection_Homo sapiens_hsa05166 | 0.19757354 |
| 99 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.19543773 |
| 100 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.18621972 |

