

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | fat-soluble vitamin catabolic process (GO:0042363) | 9.95024635 |
| 2 | vitamin catabolic process (GO:0009111) | 9.95024635 |
| 3 | regulation of female receptivity (GO:0045924) | 9.41360104 |
| 4 | mature B cell differentiation involved in immune response (GO:0002313) | 8.92825568 |
| 5 | female mating behavior (GO:0060180) | 8.15807528 |
| 6 | negative regulation of hematopoietic progenitor cell differentiation (GO:1901533) | 7.07009418 |
| 7 | mature B cell differentiation (GO:0002335) | 6.82007760 |
| 8 | phospholipase C-activating dopamine receptor signaling pathway (GO:0060158) | 6.73451644 |
| 9 | positive regulation of inositol phosphate biosynthetic process (GO:0060732) | 6.17231948 |
| 10 | detection of light stimulus involved in visual perception (GO:0050908) | 5.75425164 |
| 11 | detection of light stimulus involved in sensory perception (GO:0050962) | 5.75425164 |
| 12 | synaptic transmission, dopaminergic (GO:0001963) | 5.63827008 |
| 13 | cellular glucuronidation (GO:0052695) | 5.40008530 |
| 14 | lipoxygenase pathway (GO:0019372) | 5.36990372 |
| 15 | protein targeting to vacuole (GO:0006623) | 5.30687259 |
| 16 | protein targeting to lysosome (GO:0006622) | 5.30687259 |
| 17 | establishment of protein localization to vacuole (GO:0072666) | 5.30687259 |
| 18 | adenylate cyclase-activating dopamine receptor signaling pathway (GO:0007191) | 5.23461127 |
| 19 | response to gravity (GO:0009629) | 5.20656575 |
| 20 | glucuronate metabolic process (GO:0019585) | 5.08437660 |
| 21 | uronic acid metabolic process (GO:0006063) | 5.08437660 |
| 22 | polarized epithelial cell differentiation (GO:0030859) | 5.03132860 |
| 23 | skeletal muscle adaptation (GO:0043501) | 4.91612030 |
| 24 | embryonic heart tube development (GO:0035050) | 4.88195830 |
| 25 | regulation of inositol phosphate biosynthetic process (GO:0010919) | 4.86495947 |
| 26 | morphogenesis of an endothelium (GO:0003159) | 4.84653001 |
| 27 | endothelial tube morphogenesis (GO:0061154) | 4.84653001 |
| 28 | negative regulation of oxidoreductase activity (GO:0051354) | 4.82972268 |
| 29 | striated muscle atrophy (GO:0014891) | 4.76768447 |
| 30 | positive regulation of cAMP-mediated signaling (GO:0043950) | 4.74841742 |
| 31 | muscle filament sliding (GO:0030049) | 4.61403009 |
| 32 | actin-myosin filament sliding (GO:0033275) | 4.61403009 |
| 33 | coenzyme catabolic process (GO:0009109) | 4.59892014 |
| 34 | lymphangiogenesis (GO:0001946) | 4.54860258 |
| 35 | regulation of antigen processing and presentation of peptide antigen (GO:0002583) | 4.52709760 |
| 36 | pantothenate metabolic process (GO:0015939) | 4.51924761 |
| 37 | long term synaptic depression (GO:0060292) | 4.31487086 |
| 38 | glycosphingolipid biosynthetic process (GO:0006688) | 4.30578546 |
| 39 | regulation of MHC class II biosynthetic process (GO:0045346) | 4.29978108 |
| 40 | GTP biosynthetic process (GO:0006183) | 4.22298658 |
| 41 | neuronal action potential (GO:0019228) | 4.20383624 |
| 42 | regulation of sensory perception of pain (GO:0051930) | 4.20030904 |
| 43 | regulation of sensory perception (GO:0051931) | 4.20030904 |
| 44 | ATP synthesis coupled proton transport (GO:0015986) | 4.19167672 |
| 45 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 4.19167672 |
| 46 | muscle atrophy (GO:0014889) | 4.10749040 |
| 47 | protein localization to vacuole (GO:0072665) | 4.07418642 |
| 48 | protein localization to lysosome (GO:0061462) | 4.07418642 |
| 49 | receptor guanylyl cyclase signaling pathway (GO:0007168) | 4.02128693 |
| 50 | tissue regeneration (GO:0042246) | 3.99292308 |
| 51 | regulation of germinal center formation (GO:0002634) | 3.87402479 |
| 52 | regulation of calcineurin-NFAT signaling cascade (GO:0070884) | 3.83525248 |
| 53 | DNA deamination (GO:0045006) | 3.69583375 |
| 54 | actin-mediated cell contraction (GO:0070252) | 3.65036385 |
| 55 | transmission of nerve impulse (GO:0019226) | 3.62294348 |
| 56 | positive regulation of calcium-mediated signaling (GO:0050850) | 3.61699687 |
| 57 | primary amino compound metabolic process (GO:1901160) | 3.59063325 |
| 58 | UTP biosynthetic process (GO:0006228) | 3.58016708 |
| 59 | collecting duct development (GO:0072044) | 3.57595287 |
| 60 | protein polyglutamylation (GO:0018095) | 3.54116832 |
| 61 | pericardium development (GO:0060039) | 3.50421956 |
| 62 | positive regulation of chemokine secretion (GO:0090197) | 3.47749225 |
| 63 | positive regulation of macrophage derived foam cell differentiation (GO:0010744) | 3.43671656 |
| 64 | venous blood vessel morphogenesis (GO:0048845) | 3.40577751 |
| 65 | positive regulation of phosphatase activity (GO:0010922) | 3.38140706 |
| 66 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 3.36217879 |
| 67 | positive regulation of macrophage differentiation (GO:0045651) | 3.34010918 |
| 68 | nonmotile primary cilium assembly (GO:0035058) | 3.27417355 |
| 69 | UTP metabolic process (GO:0046051) | 3.26063129 |
| 70 | regulation of macrophage chemotaxis (GO:0010758) | 3.20852031 |
| 71 | regulation of megakaryocyte differentiation (GO:0045652) | 3.18374386 |
| 72 | response to muscle activity (GO:0014850) | 3.18149260 |
| 73 | regulation of skeletal muscle contraction (GO:0014819) | 3.17596314 |
| 74 | B cell activation involved in immune response (GO:0002312) | 3.15484894 |
| 75 | membrane depolarization during action potential (GO:0086010) | 3.15472338 |
| 76 | positive regulation of interleukin-8 secretion (GO:2000484) | 3.12937457 |
| 77 | endothelial cell development (GO:0001885) | 3.12177156 |
| 78 | multicellular organismal reproductive behavior (GO:0033057) | 3.11123029 |
| 79 | regulation of mesoderm development (GO:2000380) | 3.03965016 |
| 80 | basic amino acid transport (GO:0015802) | 3.03221112 |
| 81 | indolalkylamine metabolic process (GO:0006586) | 2.99900187 |
| 82 | positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) | 2.97150644 |
| 83 | kynurenine metabolic process (GO:0070189) | 2.95737489 |
| 84 | leukocyte tethering or rolling (GO:0050901) | 2.94941543 |
| 85 | negative regulation of muscle hypertrophy (GO:0014741) | 2.93106185 |
| 86 | activation of adenylate cyclase activity (GO:0007190) | 2.92464967 |
| 87 | apical protein localization (GO:0045176) | 2.91867826 |
| 88 | negative regulation of monooxygenase activity (GO:0032769) | 2.91507517 |
| 89 | response to amphetamine (GO:0001975) | 2.90198779 |
| 90 | L-fucose metabolic process (GO:0042354) | 2.89982723 |
| 91 | L-fucose catabolic process (GO:0042355) | 2.89982723 |
| 92 | fucose catabolic process (GO:0019317) | 2.89982723 |
| 93 | regulation of chemokine secretion (GO:0090196) | 2.89910867 |
| 94 | serotonin metabolic process (GO:0042428) | 2.88134631 |
| 95 | cGMP biosynthetic process (GO:0006182) | 2.84534776 |
| 96 | regulation of calcium-mediated signaling (GO:0050848) | 2.82806707 |
| 97 | adenosine metabolic process (GO:0046085) | 2.82335934 |
| 98 | glycosylceramide metabolic process (GO:0006677) | 2.78285971 |
| 99 | sleep (GO:0030431) | 2.77626439 |
| 100 | skeletal muscle tissue regeneration (GO:0043403) | 11.1088254 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 3.68523626 |
| 2 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 3.24360882 |
| 3 | VDR_22108803_ChIP-Seq_LS180_Human | 3.16613296 |
| 4 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 2.98059209 |
| 5 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 2.97898256 |
| 6 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 2.92425297 |
| 7 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 2.91519807 |
| 8 | GBX2_23144817_ChIP-Seq_PC3_Human | 2.58692134 |
| 9 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 2.56534438 |
| 10 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 2.48974025 |
| 11 | EZH2_22144423_ChIP-Seq_EOC_Human | 2.44669794 |
| 12 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 2.36157958 |
| 13 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 2.17557977 |
| 14 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 2.17372936 |
| 15 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 2.17251352 |
| 16 | KLF2_18264089_ChIP-ChIP_MESCs_Mouse | 2.09137346 |
| 17 | KLF5_18264089_ChIP-ChIP_MESCs_Mouse | 2.09137346 |
| 18 | KLF4_18264089_ChIP-ChIP_MESCs_Mouse | 2.09137346 |
| 19 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 2.05776721 |
| 20 | EWS_26573619_Chip-Seq_HEK293_Human | 2.03981932 |
| 21 | FUS_26573619_Chip-Seq_HEK293_Human | 2.00619881 |
| 22 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 1.97183428 |
| 23 | ESR1_20079471_ChIP-ChIP_T-47D_Human | 1.96535550 |
| 24 | TDRD3_21172665_ChIP-Seq_MCF-7_Human | 1.96192491 |
| 25 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.95461422 |
| 26 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.94910129 |
| 27 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.94610488 |
| 28 | RNF2_16625203_ChIP-ChIP_MESCs_Mouse | 1.93568691 |
| 29 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.86965297 |
| 30 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.84285832 |
| 31 | NCOR_22424771_ChIP-Seq_293T_Human | 1.69432674 |
| 32 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 1.66394950 |
| 33 | ZNF652_21678463_ChIP-ChIP_ZR75-1_Human | 1.65392768 |
| 34 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.62623374 |
| 35 | CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human | 1.62043571 |
| 36 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 1.57483033 |
| 37 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 1.56761252 |
| 38 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 1.55239318 |
| 39 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.54007569 |
| 40 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 1.50671558 |
| 41 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.50634291 |
| 42 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.50242035 |
| 43 | LMO2_20887958_ChIP-Seq_HPC-7_Mouse | 1.49625754 |
| 44 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.47101224 |
| 45 | SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 1.46698954 |
| 46 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 1.45425045 |
| 47 | CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 1.44787742 |
| 48 | ARNT_22903824_ChIP-Seq_MCF-7_Human | 1.44490887 |
| 49 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.42432177 |
| 50 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 1.40732447 |
| 51 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 1.40248202 |
| 52 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 1.38949073 |
| 53 | DROSHA_22980978_ChIP-Seq_HELA_Human | 1.34479804 |
| 54 | FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 1.33840275 |
| 55 | STAT3_23295773_ChIP-Seq_U87_Human | 1.32837418 |
| 56 | SMAD4_21799915_ChIP-Seq_A2780_Human | 1.31668669 |
| 57 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 1.31238560 |
| 58 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 1.30174742 |
| 59 | FLI1_21867929_ChIP-Seq_TH2_Mouse | 1.29558298 |
| 60 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.27841387 |
| 61 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.26967855 |
| 62 | P53_21459846_ChIP-Seq_SAOS-2_Human | 1.26372660 |
| 63 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 1.24780782 |
| 64 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 1.21745221 |
| 65 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.20252906 |
| 66 | EZH2_18974828_ChIP-Seq_MESCs_Mouse | 1.19510072 |
| 67 | RNF2_18974828_ChIP-Seq_MESCs_Mouse | 1.19510072 |
| 68 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 1.19394133 |
| 69 | SOX2_21211035_ChIP-Seq_LN229_Human | 1.18921172 |
| 70 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.18708771 |
| 71 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.18708771 |
| 72 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.17773102 |
| 73 | GATA2_20887958_ChIP-Seq_HPC-7_Mouse | 1.16469315 |
| 74 | P300_19829295_ChIP-Seq_ESCs_Human | 1.16268464 |
| 75 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.15980071 |
| 76 | TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse | 1.15845710 |
| 77 | TCF4_23295773_ChIP-Seq_U87_Human | 1.15599043 |
| 78 | TP53_20018659_ChIP-ChIP_R1E_Mouse | 1.13559667 |
| 79 | EBNA1_20929547_Chip-Seq_RAJI-cells_Human | 1.10080016 |
| 80 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 1.08276597 |
| 81 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.08276597 |
| 82 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.08017660 |
| 83 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 1.07219471 |
| 84 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 1.04187046 |
| 85 | SMAD4_21741376_ChIP-Seq_EPCs_Human | 1.03792487 |
| 86 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.03552364 |
| 87 | RAC3_21632823_ChIP-Seq_H3396_Human | 1.02616283 |
| 88 | TAF2_19829295_ChIP-Seq_ESCs_Human | 1.02426371 |
| 89 | BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human | 1.01888968 |
| 90 | MYC_19829295_ChIP-Seq_ESCs_Human | 1.01130689 |
| 91 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 1.00773734 |
| 92 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 0.99450238 |
| 93 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 0.98929963 |
| 94 | PPARD_23208498_ChIP-Seq_MDA-MB-231_Human | 0.97833640 |
| 95 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 0.97324894 |
| 96 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 0.94929645 |
| 97 | REST_21632747_ChIP-Seq_MESCs_Mouse | 0.94692595 |
| 98 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 0.92925696 |
| 99 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 0.92099162 |
| 100 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 0.91150837 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0002653_abnormal_ependyma_morphology | 8.86181707 |
| 2 | MP0002736_abnormal_nociception_after | 6.58818370 |
| 3 | MP0001968_abnormal_touch/_nociception | 5.02549675 |
| 4 | MP0005360_urolithiasis | 4.47627515 |
| 5 | MP0005409_darkened_coat_color | 4.29949921 |
| 6 | MP0005083_abnormal_biliary_tract | 3.54235733 |
| 7 | MP0009697_abnormal_copulation | 3.23478266 |
| 8 | MP0003172_abnormal_lysosome_physiology | 3.19386835 |
| 9 | MP0009840_abnormal_foam_cell | 3.12079323 |
| 10 | MP0006276_abnormal_autonomic_nervous | 2.85605125 |
| 11 | MP0002909_abnormal_adrenal_gland | 2.80083915 |
| 12 | MP0000678_abnormal_parathyroid_gland | 2.74228882 |
| 13 | MP0004145_abnormal_muscle_electrophysio | 2.38942210 |
| 14 | MP0002734_abnormal_mechanical_nocicepti | 2.37813747 |
| 15 | MP0003646_muscle_fatigue | 2.33873155 |
| 16 | MP0002277_abnormal_respiratory_mucosa | 2.16309469 |
| 17 | MP0003724_increased_susceptibility_to | 1.75486043 |
| 18 | MP0001879_abnormal_lymphatic_vessel | 1.70246024 |
| 19 | MP0002928_abnormal_bile_duct | 1.58589925 |
| 20 | MP0005646_abnormal_pituitary_gland | 1.55261654 |
| 21 | MP0000747_muscle_weakness | 1.53983394 |
| 22 | MP0003950_abnormal_plasma_membrane | 1.53136831 |
| 23 | MP0001873_stomach_inflammation | 1.47739310 |
| 24 | MP0002148_abnormal_hypersensitivity_rea | 1.33898519 |
| 25 | MP0004036_abnormal_muscle_relaxation | 1.32076237 |
| 26 | MP0009053_abnormal_anal_canal | 1.28497637 |
| 27 | MP0005671_abnormal_response_to | 1.26362277 |
| 28 | MP0006072_abnormal_retinal_apoptosis | 1.22312127 |
| 29 | MP0002108_abnormal_muscle_morphology | 1.21650515 |
| 30 | MP0004742_abnormal_vestibular_system | 1.18841871 |
| 31 | MP0001984_abnormal_olfaction | 1.15730669 |
| 32 | MP0001970_abnormal_pain_threshold | 1.15352166 |
| 33 | MP0003136_yellow_coat_color | 1.10049400 |
| 34 | MP0002837_dystrophic_cardiac_calcinosis | 1.05162194 |
| 35 | MP0002933_joint_inflammation | 1.05078625 |
| 36 | MP0000049_abnormal_middle_ear | 1.04629529 |
| 37 | MP0003938_abnormal_ear_development | 1.04147432 |
| 38 | MP0004130_abnormal_muscle_cell | 1.02959813 |
| 39 | MP0000631_abnormal_neuroendocrine_gland | 0.98376400 |
| 40 | MP0009250_abnormal_appendicular_skeleto | 0.94915212 |
| 41 | MP0006292_abnormal_olfactory_placode | 0.94379225 |
| 42 | MP0002089_abnormal_postnatal_growth/wei | 0.93355629 |
| 43 | MP0002282_abnormal_trachea_morphology | 0.93090659 |
| 44 | MP0000537_abnormal_urethra_morphology | 0.93024309 |
| 45 | MP0008789_abnormal_olfactory_epithelium | 0.92927946 |
| 46 | MP0000467_abnormal_esophagus_morphology | 0.92569558 |
| 47 | MP0003119_abnormal_digestive_system | 0.92186817 |
| 48 | MP0000749_muscle_degeneration | 0.91504177 |
| 49 | MP0002098_abnormal_vibrissa_morphology | 0.86661730 |
| 50 | MP0002269_muscular_atrophy | 0.86091718 |
| 51 | MP0003718_maternal_effect | 0.83440937 |
| 52 | MP0002127_abnormal_cardiovascular_syste | 0.83319459 |
| 53 | MP0008872_abnormal_physiological_respon | 0.80439260 |
| 54 | MP0002735_abnormal_chemical_nociception | 0.79856287 |
| 55 | MP0000759_abnormal_skeletal_muscle | 0.79360969 |
| 56 | MP0002272_abnormal_nervous_system | 0.77767265 |
| 57 | MP0003195_calcinosis | 0.76302214 |
| 58 | MP0002896_abnormal_bone_mineralization | 0.75308057 |
| 59 | MP0000230_abnormal_systemic_arterial | 0.72035487 |
| 60 | MP0001502_abnormal_circadian_rhythm | 0.71289434 |
| 61 | MP0002102_abnormal_ear_morphology | 0.68057066 |
| 62 | MP0004085_abnormal_heartbeat | 0.67832688 |
| 63 | MP0000470_abnormal_stomach_morphology | 0.67119722 |
| 64 | MP0002138_abnormal_hepatobiliary_system | 0.65253118 |
| 65 | MP0005551_abnormal_eye_electrophysiolog | 0.64533672 |
| 66 | MP0005253_abnormal_eye_physiology | 0.63878587 |
| 67 | MP0003252_abnormal_bile_duct | 0.63576084 |
| 68 | MP0005084_abnormal_gallbladder_morpholo | 0.63375654 |
| 69 | MP0002106_abnormal_muscle_physiology | 0.63118403 |
| 70 | MP0001963_abnormal_hearing_physiology | 0.61766274 |
| 71 | MP0000372_irregular_coat_pigmentation | 0.61266330 |
| 72 | MP0000534_abnormal_ureter_morphology | 0.60968378 |
| 73 | MP0003959_abnormal_lean_body | 0.60810833 |
| 74 | MP0005369_muscle_phenotype | 0.60615786 |
| 75 | MP0010771_integument_phenotype | 0.57946351 |
| 76 | MP0004381_abnormal_hair_follicle | 0.57126238 |
| 77 | MP0000465_gastrointestinal_hemorrhage | 0.56025258 |
| 78 | MP0002249_abnormal_larynx_morphology | 0.55027473 |
| 79 | MP0004087_abnormal_muscle_fiber | 0.54765027 |
| 80 | MP0000613_abnormal_salivary_gland | 0.53477919 |
| 81 | MP0003937_abnormal_limbs/digits/tail_de | 0.52663522 |
| 82 | MP0002733_abnormal_thermal_nociception | 0.52559204 |
| 83 | MP0005620_abnormal_muscle_contractility | 0.51921776 |
| 84 | MP0000516_abnormal_urinary_system | 0.50534574 |
| 85 | MP0005367_renal/urinary_system_phenotyp | 0.50534574 |
| 86 | MP0001800_abnormal_humoral_immune | 0.49227555 |
| 87 | MP0001485_abnormal_pinna_reflex | 0.48583391 |
| 88 | MP0000026_abnormal_inner_ear | 0.48219713 |
| 89 | MP0000538_abnormal_urinary_bladder | 0.48177603 |
| 90 | MP0002572_abnormal_emotion/affect_behav | 0.46114991 |
| 91 | MP0005000_abnormal_immune_tolerance | 0.45876546 |
| 92 | MP0000249_abnormal_blood_vessel | 0.44673073 |
| 93 | MP0004885_abnormal_endolymph | 0.44573480 |
| 94 | MP0009745_abnormal_behavioral_response | 0.44332498 |
| 95 | MP0003879_abnormal_hair_cell | 0.42421350 |
| 96 | MP0002075_abnormal_coat/hair_pigmentati | 0.41625417 |
| 97 | MP0005394_taste/olfaction_phenotype | 0.41309012 |
| 98 | MP0005499_abnormal_olfactory_system | 0.41309012 |
| 99 | MP0004859_abnormal_synaptic_plasticity | 0.40427797 |
| 100 | MP0000377_abnormal_hair_follicle | 0.40368362 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 6.91975569 |
| 2 | Absent/shortened dynein arms (HP:0200106) | 6.91975569 |
| 3 | Absent phalangeal crease (HP:0006109) | 6.07135588 |
| 4 | Abnormality of cochlea (HP:0000375) | 5.67285406 |
| 5 | Distal arthrogryposis (HP:0005684) | 5.41941532 |
| 6 | Ulnar deviation of the wrist (HP:0003049) | 5.37896150 |
| 7 | Failure to thrive in infancy (HP:0001531) | 5.25030294 |
| 8 | Round ear (HP:0100830) | 5.23115257 |
| 9 | Abnormal finger flexion creases (HP:0006143) | 5.17125057 |
| 10 | Decreased central vision (HP:0007663) | 5.10125847 |
| 11 | Dysautonomia (HP:0002459) | 4.92619362 |
| 12 | Poor head control (HP:0002421) | 4.65608784 |
| 13 | Calcaneovalgus deformity (HP:0001848) | 4.54167111 |
| 14 | Morphological abnormality of the inner ear (HP:0011390) | 4.44127597 |
| 15 | Keratoconjunctivitis sicca (HP:0001097) | 4.41746824 |
| 16 | Abolished electroretinogram (ERG) (HP:0000550) | 4.41571167 |
| 17 | Deformed tarsal bones (HP:0008119) | 4.24498909 |
| 18 | Tinnitus (HP:0000360) | 4.24054923 |
| 19 | Constricted visual fields (HP:0001133) | 4.19324323 |
| 20 | Keratoconjunctivitis (HP:0001096) | 4.16816604 |
| 21 | Bony spicule pigmentary retinopathy (HP:0007737) | 4.04205824 |
| 22 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 3.93131412 |
| 23 | Follicular hyperkeratosis (HP:0007502) | 3.77938814 |
| 24 | Abnormal respiratory motile cilium morphology (HP:0005938) | 3.72756698 |
| 25 | Abnormal respiratory epithelium morphology (HP:0012253) | 3.72756698 |
| 26 | Attenuation of retinal blood vessels (HP:0007843) | 3.60554005 |
| 27 | Generalized aminoaciduria (HP:0002909) | 3.54026338 |
| 28 | Lymphangioma (HP:0100764) | 3.46072251 |
| 29 | Abnormal ciliary motility (HP:0012262) | 3.36153810 |
| 30 | Morphological abnormality of the middle ear (HP:0008609) | 3.27304936 |
| 31 | Palpebral edema (HP:0100540) | 3.22701345 |
| 32 | Nemaline bodies (HP:0003798) | 3.15470507 |
| 33 | Abnormality of the costochondral junction (HP:0000919) | 3.11989295 |
| 34 | Keratoconus (HP:0000563) | 3.10163058 |
| 35 | Increased corneal curvature (HP:0100692) | 3.10163058 |
| 36 | Abnormality of the proximal phalanges of the hand (HP:0009834) | 3.04936959 |
| 37 | Cone-rod dystrophy (HP:0000548) | 2.97706244 |
| 38 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 2.94744967 |
| 39 | Nonimmune hydrops fetalis (HP:0001790) | 2.92803767 |
| 40 | Abnormal autonomic nervous system physiology (HP:0012332) | 2.85337395 |
| 41 | Recurrent sinusitis (HP:0011108) | 2.80217224 |
| 42 | Impaired pain sensation (HP:0007328) | 2.67139109 |
| 43 | Abnormality of pain sensation (HP:0010832) | 2.67139109 |
| 44 | Absent eyebrow (HP:0002223) | 2.57592980 |
| 45 | Muscle fiber inclusion bodies (HP:0100299) | 2.51884277 |
| 46 | Muscle fiber cytoplasmatic inclusion bodies (HP:0100303) | 2.50842568 |
| 47 | Abnormal respiratory motile cilium physiology (HP:0012261) | 2.46083547 |
| 48 | Abnormality of the peritoneum (HP:0002585) | 2.43940850 |
| 49 | B lymphocytopenia (HP:0010976) | 2.40862065 |
| 50 | Stenosis of the external auditory canal (HP:0000402) | 2.38082952 |
| 51 | Chest pain (HP:0100749) | 2.32855343 |
| 52 | Abnormality of the renal collecting system (HP:0004742) | 2.30994256 |
| 53 | Periorbital edema (HP:0100539) | 2.30853924 |
| 54 | Congenital stationary night blindness (HP:0007642) | 2.28894306 |
| 55 | Absent eyelashes (HP:0000561) | 2.22101553 |
| 56 | Abnormality of the middle phalanges of the toes (HP:0010183) | 2.19529676 |
| 57 | Symphalangism affecting the phalanges of the hand (HP:0009773) | 2.19164922 |
| 58 | Facial edema (HP:0000282) | 2.18091633 |
| 59 | Mesangial abnormality (HP:0001966) | 2.17961930 |
| 60 | Mask-like facies (HP:0000298) | 2.17132277 |
| 61 | Abnormality of the calcaneus (HP:0008364) | 2.16316509 |
| 62 | Progressive microcephaly (HP:0000253) | 2.15787336 |
| 63 | Abnormality of the nasal septum (HP:0000419) | 2.15037718 |
| 64 | Long nose (HP:0003189) | 2.09547159 |
| 65 | Exercise-induced myalgia (HP:0003738) | 2.08543969 |
| 66 | Thyroiditis (HP:0100646) | 2.07332392 |
| 67 | Abnormality of B cell number (HP:0010975) | 2.03903904 |
| 68 | Abnormality of the middle phalanx of the 5th finger (HP:0004219) | 2.03834965 |
| 69 | Hypotrichosis (HP:0001006) | 2.00487437 |
| 70 | Elevated circulating parathyroid hormone (PTH) level (HP:0003165) | 1.99578260 |
| 71 | Enlarged epiphyses (HP:0010580) | 1.95703992 |
| 72 | Pustule (HP:0200039) | 1.95080555 |
| 73 | Mesomelia (HP:0003027) | 1.94177963 |
| 74 | Keratitis (HP:0000491) | 1.93726749 |
| 75 | Lip pit (HP:0100267) | 1.93347272 |
| 76 | Tarsal synostosis (HP:0008368) | 1.91222173 |
| 77 | Short 1st metacarpal (HP:0010034) | 1.87996521 |
| 78 | Aplasia/Hypoplasia of the 1st metacarpal (HP:0010026) | 1.87996521 |
| 79 | Synostosis involving the elbow (HP:0003938) | 1.87296125 |
| 80 | Humeroradial synostosis (HP:0003041) | 1.87296125 |
| 81 | Ulnar deviation of finger (HP:0009465) | 1.86574095 |
| 82 | Abnormality of the phalanges of the 5th finger (HP:0004213) | 1.86398483 |
| 83 | Abnormality of glutamine family amino acid metabolism (HP:0010902) | 1.85387336 |
| 84 | Delayed epiphyseal ossification (HP:0002663) | 1.84744755 |
| 85 | Amaurosis fugax (HP:0100576) | 1.80415041 |
| 86 | Severe combined immunodeficiency (HP:0004430) | 1.80384492 |
| 87 | Short hallux (HP:0010109) | 1.80323175 |
| 88 | Thin bony cortex (HP:0002753) | 1.76182365 |
| 89 | Neoplasm of the heart (HP:0100544) | 1.76128607 |
| 90 | Synostosis involving bones of the feet (HP:0009140) | 1.75364530 |
| 91 | Synostosis involving bones of the lower limbs (HP:0009138) | 1.75364530 |
| 92 | Down-sloping shoulders (HP:0200021) | 1.74874992 |
| 93 | Type 1 muscle fiber predominance (HP:0003803) | 1.73819032 |
| 94 | Short tibia (HP:0005736) | 1.73481670 |
| 95 | Aplasia/Hypoplasia of the phalanges of the toes (HP:0010173) | 1.73474975 |
| 96 | Photophobia (HP:0000613) | 1.72667446 |
| 97 | Arterial thrombosis (HP:0004420) | 1.72281785 |
| 98 | Vertigo (HP:0002321) | 1.70923951 |
| 99 | Congenital, generalized hypertrichosis (HP:0004540) | 1.69716001 |
| 100 | Autoimmune thrombocytopenia (HP:0001973) | 1.68381549 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MAP2K2 | 4.66178417 |
| 2 | NUAK1 | 3.85268327 |
| 3 | TAOK3 | 3.75894176 |
| 4 | ZAK | 3.59193638 |
| 5 | CDK4 | 3.10024069 |
| 6 | GRK1 | 2.98934603 |
| 7 | MAP4K2 | 2.72810320 |
| 8 | TIE1 | 2.63778335 |
| 9 | VRK2 | 2.58182239 |
| 10 | OBSCN | 2.52924593 |
| 11 | STK38 | 2.44981555 |
| 12 | TXK | 2.16541229 |
| 13 | FRK | 2.14734982 |
| 14 | CAMKK2 | 1.99517557 |
| 15 | CHEK2 | 1.92236831 |
| 16 | TAF1 | 1.91609575 |
| 17 | PHKG2 | 1.83321749 |
| 18 | PHKG1 | 1.83321749 |
| 19 | MAP2K1 | 1.79771167 |
| 20 | TLK1 | 1.79476145 |
| 21 | PIK3CA | 1.76974568 |
| 22 | BMPR1B | 1.76035099 |
| 23 | CSNK1G3 | 1.66879651 |
| 24 | CSNK1A1L | 1.54566821 |
| 25 | KDR | 1.50563100 |
| 26 | VRK1 | 1.42837825 |
| 27 | CSNK1G1 | 1.42722162 |
| 28 | ADRBK2 | 1.36780554 |
| 29 | CAMK1D | 1.34691946 |
| 30 | DAPK1 | 1.33097149 |
| 31 | WNK4 | 1.26872712 |
| 32 | CSNK1G2 | 1.21747522 |
| 33 | MYLK | 1.11889567 |
| 34 | CDK12 | 1.11806572 |
| 35 | JAK3 | 1.04246539 |
| 36 | MUSK | 1.01188426 |
| 37 | PIK3CG | 0.98534995 |
| 38 | GRK5 | 0.89046943 |
| 39 | INSRR | 0.88299993 |
| 40 | PINK1 | 0.83961027 |
| 41 | MAPK13 | 0.81126884 |
| 42 | PAK4 | 0.78887486 |
| 43 | TEC | 0.75823182 |
| 44 | AURKA | 0.75139320 |
| 45 | MAP4K1 | 0.74428372 |
| 46 | SYK | 0.72942029 |
| 47 | MAP3K12 | 0.72011353 |
| 48 | PLK2 | 0.71919980 |
| 49 | TESK2 | 0.69784423 |
| 50 | IKBKB | 0.67152108 |
| 51 | PTK2B | 0.66324429 |
| 52 | ZAP70 | 0.66305901 |
| 53 | CCNB1 | 0.65275472 |
| 54 | MAPK4 | 0.64716833 |
| 55 | MAPK15 | 0.63026781 |
| 56 | MAPKAPK5 | 0.62568030 |
| 57 | GRK6 | 0.62279002 |
| 58 | CAMK1 | 0.61994709 |
| 59 | CAMK2B | 0.59823142 |
| 60 | CAMK2G | 0.56550308 |
| 61 | CDK6 | 0.55896651 |
| 62 | RIPK4 | 0.54189752 |
| 63 | PRKCZ | 0.50038151 |
| 64 | OXSR1 | 0.48339055 |
| 65 | ERBB2 | 0.45972237 |
| 66 | WNK3 | 0.45911995 |
| 67 | CAMK1G | 0.45091304 |
| 68 | PRKCA | 0.43140610 |
| 69 | CSNK1A1 | 0.43012698 |
| 70 | PRKCQ | 0.41960430 |
| 71 | KIT | 0.41673564 |
| 72 | ITK | 0.41318939 |
| 73 | PIM1 | 0.40172167 |
| 74 | RPS6KA5 | 0.39974993 |
| 75 | PLK3 | 0.39356658 |
| 76 | PTK2 | 0.38984362 |
| 77 | ILK | 0.37928091 |
| 78 | MAP3K11 | 0.37691699 |
| 79 | STK39 | 0.37662672 |
| 80 | IRAK1 | 0.37567925 |
| 81 | PRKCE | 0.37198524 |
| 82 | LCK | 0.37077972 |
| 83 | BLK | 0.36202077 |
| 84 | MST4 | 0.36005693 |
| 85 | MAP2K6 | 0.35992258 |
| 86 | PRKACA | 0.35251774 |
| 87 | MAPKAPK3 | 0.34649115 |
| 88 | LYN | 0.32217267 |
| 89 | MAPKAPK2 | 0.31736707 |
| 90 | BCKDK | 0.30445030 |
| 91 | SMG1 | 0.30046910 |
| 92 | CAMKK1 | 0.29178086 |
| 93 | DAPK3 | 0.27298897 |
| 94 | PRKCB | 0.27167735 |
| 95 | IKBKE | 0.27132790 |
| 96 | CSNK2A1 | 0.27089063 |
| 97 | ABL2 | 0.26707945 |
| 98 | BTK | 0.26406338 |
| 99 | ADRBK1 | 0.25959297 |
| 100 | CAMK2A | 0.25572891 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 4.19479092 |
| 2 | Sulfur metabolism_Homo sapiens_hsa00920 | 3.48946067 |
| 3 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 3.31391022 |
| 4 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 3.05393387 |
| 5 | Olfactory transduction_Homo sapiens_hsa04740 | 3.02491025 |
| 6 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 2.93138066 |
| 7 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 2.63007250 |
| 8 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 2.61293615 |
| 9 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 2.54069431 |
| 10 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 2.51399772 |
| 11 | Phototransduction_Homo sapiens_hsa04744 | 2.48478505 |
| 12 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 2.42377671 |
| 13 | Retinol metabolism_Homo sapiens_hsa00830 | 2.37160663 |
| 14 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 2.35873915 |
| 15 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 2.30277773 |
| 16 | Asthma_Homo sapiens_hsa05310 | 2.08995072 |
| 17 | Histidine metabolism_Homo sapiens_hsa00340 | 1.90891040 |
| 18 | Sulfur relay system_Homo sapiens_hsa04122 | 1.85085313 |
| 19 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.72611277 |
| 20 | Homologous recombination_Homo sapiens_hsa03440 | 1.57408508 |
| 21 | Allograft rejection_Homo sapiens_hsa05330 | 1.57128333 |
| 22 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 1.51014121 |
| 23 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 1.50620800 |
| 24 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.50049053 |
| 25 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 1.49324988 |
| 26 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 1.43274522 |
| 27 | Ether lipid metabolism_Homo sapiens_hsa00565 | 1.39724449 |
| 28 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 1.36837538 |
| 29 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 1.29601256 |
| 30 | Renin secretion_Homo sapiens_hsa04924 | 1.25910050 |
| 31 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 1.22353266 |
| 32 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.19669333 |
| 33 | Parkinsons disease_Homo sapiens_hsa05012 | 1.19371405 |
| 34 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.15900405 |
| 35 | Calcium signaling pathway_Homo sapiens_hsa04020 | 1.15656539 |
| 36 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.15276770 |
| 37 | Alzheimers disease_Homo sapiens_hsa05010 | 1.14964365 |
| 38 | Circadian entrainment_Homo sapiens_hsa04713 | 1.03436310 |
| 39 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.01687654 |
| 40 | Taste transduction_Homo sapiens_hsa04742 | 0.99352119 |
| 41 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.97527005 |
| 42 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.91837483 |
| 43 | Protein digestion and absorption_Homo sapiens_hsa04974 | 0.91451554 |
| 44 | Gastric acid secretion_Homo sapiens_hsa04971 | 0.88501694 |
| 45 | Ribosome_Homo sapiens_hsa03010 | 0.85942624 |
| 46 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.85726513 |
| 47 | Nicotine addiction_Homo sapiens_hsa05033 | 0.85437750 |
| 48 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.83406414 |
| 49 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.81839799 |
| 50 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.81375034 |
| 51 | ABC transporters_Homo sapiens_hsa02010 | 0.78329387 |
| 52 | Tight junction_Homo sapiens_hsa04530 | 0.76470732 |
| 53 | Insulin secretion_Homo sapiens_hsa04911 | 0.76213289 |
| 54 | Legionellosis_Homo sapiens_hsa05134 | 0.74762508 |
| 55 | RNA polymerase_Homo sapiens_hsa03020 | 0.69432652 |
| 56 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.69429132 |
| 57 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.68703016 |
| 58 | RNA degradation_Homo sapiens_hsa03018 | 0.68648498 |
| 59 | Proteasome_Homo sapiens_hsa03050 | 0.61108424 |
| 60 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.59580928 |
| 61 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.59499307 |
| 62 | Viral myocarditis_Homo sapiens_hsa05416 | 0.56434695 |
| 63 | cAMP signaling pathway_Homo sapiens_hsa04024 | 0.53709667 |
| 64 | Dopaminergic synapse_Homo sapiens_hsa04728 | 0.52344895 |
| 65 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.51022028 |
| 66 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 0.50998914 |
| 67 | Mismatch repair_Homo sapiens_hsa03430 | 0.49941685 |
| 68 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.49089973 |
| 69 | Lysine degradation_Homo sapiens_hsa00310 | 0.47688798 |
| 70 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.47559240 |
| 71 | Protein export_Homo sapiens_hsa03060 | 0.46385608 |
| 72 | Huntingtons disease_Homo sapiens_hsa05016 | 0.44052472 |
| 73 | Purine metabolism_Homo sapiens_hsa00230 | 0.43429605 |
| 74 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 0.43365708 |
| 75 | Morphine addiction_Homo sapiens_hsa05032 | 0.41197361 |
| 76 | DNA replication_Homo sapiens_hsa03030 | 0.40222627 |
| 77 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 0.38582099 |
| 78 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.36996237 |
| 79 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.36870251 |
| 80 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.36278091 |
| 81 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.34107529 |
| 82 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.32647766 |
| 83 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.32617589 |
| 84 | Metabolic pathways_Homo sapiens_hsa01100 | 0.30204643 |
| 85 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.29991877 |
| 86 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.29862813 |
| 87 | Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410 | 0.29484154 |
| 88 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.29415805 |
| 89 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.29121124 |
| 90 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.28407956 |
| 91 | Salivary secretion_Homo sapiens_hsa04970 | 0.27588599 |
| 92 | Peroxisome_Homo sapiens_hsa04146 | 0.27257095 |
| 93 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.27020586 |
| 94 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.23875848 |
| 95 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.23795143 |
| 96 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 0.22699670 |
| 97 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.22524259 |
| 98 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.17374204 |
| 99 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 0.16535749 |
| 100 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 0.16382834 |

