

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 5.71787904 |
| 2 | DNA deamination (GO:0045006) | 5.42110118 |
| 3 | chaperone-mediated protein transport (GO:0072321) | 5.26805176 |
| 4 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 5.13416730 |
| 5 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 5.13416730 |
| 6 | proteasome assembly (GO:0043248) | 4.96241263 |
| 7 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 4.90539774 |
| 8 | ATP synthesis coupled proton transport (GO:0015986) | 4.90539774 |
| 9 | protein deneddylation (GO:0000338) | 4.84493556 |
| 10 | protein-cofactor linkage (GO:0018065) | 4.60530924 |
| 11 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 4.60415108 |
| 12 | cullin deneddylation (GO:0010388) | 4.56489908 |
| 13 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 4.36153502 |
| 14 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 4.36153502 |
| 15 | NADH dehydrogenase complex assembly (GO:0010257) | 4.36153502 |
| 16 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 4.12092621 |
| 17 | protein neddylation (GO:0045116) | 4.08411997 |
| 18 | intracellular protein transmembrane import (GO:0044743) | 4.04930600 |
| 19 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 4.03426613 |
| 20 | adenosine metabolic process (GO:0046085) | 3.91336152 |
| 21 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.85293603 |
| 22 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 3.76663024 |
| 23 | regulation of cellular amino acid metabolic process (GO:0006521) | 3.69686900 |
| 24 | maturation of 5.8S rRNA (GO:0000460) | 3.69446809 |
| 25 | negative regulation of thymocyte apoptotic process (GO:0070244) | 3.69171598 |
| 26 | respiratory electron transport chain (GO:0022904) | 3.68323634 |
| 27 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 3.66716943 |
| 28 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 3.66716943 |
| 29 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 3.63746790 |
| 30 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 3.63746790 |
| 31 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 3.63746790 |
| 32 | DNA damage response, detection of DNA damage (GO:0042769) | 3.62207290 |
| 33 | protein complex biogenesis (GO:0070271) | 3.61894987 |
| 34 | electron transport chain (GO:0022900) | 3.61284425 |
| 35 | water-soluble vitamin biosynthetic process (GO:0042364) | 3.58651269 |
| 36 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 3.58485615 |
| 37 | respiratory chain complex IV assembly (GO:0008535) | 3.54766604 |
| 38 | protein peptidyl-prolyl isomerization (GO:0000413) | 3.53243724 |
| 39 | chaperone mediated protein folding requiring cofactor (GO:0051085) | 3.52837575 |
| 40 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 3.47045648 |
| 41 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 3.47045648 |
| 42 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.41784131 |
| 43 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 3.41324327 |
| 44 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 3.37149510 |
| 45 | autophagic vacuole fusion (GO:0000046) | 3.36269892 |
| 46 | rRNA modification (GO:0000154) | 3.31773051 |
| 47 | DNA catabolic process, exonucleolytic (GO:0000738) | 3.30974794 |
| 48 | IMP biosynthetic process (GO:0006188) | 3.30847297 |
| 49 | pseudouridine synthesis (GO:0001522) | 3.28632727 |
| 50 | negative regulation of ligase activity (GO:0051352) | 3.26694847 |
| 51 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 3.26694847 |
| 52 | regulation of T-helper 1 cell differentiation (GO:0045625) | 3.25196626 |
| 53 | RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503) | 3.19971976 |
| 54 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO: | 3.18651682 |
| 55 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 3.06944174 |
| 56 | protein targeting to mitochondrion (GO:0006626) | 3.06138409 |
| 57 | cellular response to interferon-beta (GO:0035458) | 3.05054652 |
| 58 | protein localization to mitochondrion (GO:0070585) | 3.04147698 |
| 59 | intracellular protein transmembrane transport (GO:0065002) | 3.04098778 |
| 60 | positive regulation of antigen processing and presentation (GO:0002579) | 3.02495248 |
| 61 | antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590) | 3.00783248 |
| 62 | ATP biosynthetic process (GO:0006754) | 3.00547482 |
| 63 | purine nucleoside triphosphate biosynthetic process (GO:0009145) | 2.97556001 |
| 64 | tRNA processing (GO:0008033) | 2.96707145 |
| 65 | rRNA methylation (GO:0031167) | 2.93993593 |
| 66 | purine ribonucleoside triphosphate biosynthetic process (GO:0009206) | 2.93002341 |
| 67 | rRNA catabolic process (GO:0016075) | 2.91752625 |
| 68 | ubiquinone biosynthetic process (GO:0006744) | 2.89908936 |
| 69 | purine nucleobase biosynthetic process (GO:0009113) | 2.88326854 |
| 70 | establishment of protein localization to mitochondrion (GO:0072655) | 2.87925175 |
| 71 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 2.87442440 |
| 72 | organelle membrane fusion (GO:0090174) | 2.86692476 |
| 73 | protein localization to peroxisome (GO:0072662) | 2.86088653 |
| 74 | protein targeting to peroxisome (GO:0006625) | 2.86088653 |
| 75 | establishment of protein localization to peroxisome (GO:0072663) | 2.86088653 |
| 76 | positive regulation of mitochondrial fission (GO:0090141) | 2.85735401 |
| 77 | deoxyribonucleoside triphosphate metabolic process (GO:0009200) | 2.85180106 |
| 78 | positive regulation of ubiquitin-protein transferase activity (GO:0051443) | 2.81158371 |
| 79 | positive regulation of cell cycle arrest (GO:0071158) | 2.78423836 |
| 80 | peptidyl-proline modification (GO:0018208) | 2.76487740 |
| 81 | ubiquinone metabolic process (GO:0006743) | 2.75235081 |
| 82 | purine nucleotide salvage (GO:0032261) | 2.75101290 |
| 83 | positive thymic T cell selection (GO:0045059) | 2.74876237 |
| 84 | de novo protein folding (GO:0006458) | 2.73555955 |
| 85 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 2.73198827 |
| 86 | regulation of cellular amine metabolic process (GO:0033238) | 2.71725491 |
| 87 | purine deoxyribonucleoside triphosphate metabolic process (GO:0009215) | 2.71111995 |
| 88 | response to interferon-beta (GO:0035456) | 2.70413105 |
| 89 | positive regulation of ligase activity (GO:0051351) | 2.70122918 |
| 90 | purine ribonucleoside monophosphate biosynthetic process (GO:0009168) | 2.69402818 |
| 91 | purine nucleoside monophosphate biosynthetic process (GO:0009127) | 2.69402818 |
| 92 | GTP biosynthetic process (GO:0006183) | 2.69109395 |
| 93 | oxidative phosphorylation (GO:0006119) | 2.68368589 |
| 94 | protein transmembrane transport (GO:0071806) | 2.68292070 |
| 95 | ribonucleoprotein complex disassembly (GO:0032988) | 2.67154958 |
| 96 | DNA damage response, signal transduction by p53 class mediator (GO:0030330) | 2.66816508 |
| 97 | AMP metabolic process (GO:0046033) | 2.66675181 |
| 98 | regulation of thymocyte apoptotic process (GO:0070243) | 2.66117750 |
| 99 | de novo posttranslational protein folding (GO:0051084) | 2.65980954 |
| 100 | negative regulation of B cell apoptotic process (GO:0002903) | 2.65379531 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 4.36159335 |
| 2 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 4.36117434 |
| 3 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 4.05780829 |
| 4 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 3.87526517 |
| 5 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.83237271 |
| 6 | VDR_22108803_ChIP-Seq_LS180_Human | 3.43074040 |
| 7 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 3.30656774 |
| 8 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 3.22666658 |
| 9 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 3.12483033 |
| 10 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 3.12206170 |
| 11 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 3.12014755 |
| 12 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.94234698 |
| 13 | IGF1R_20145208_ChIP-Seq_DFB_Human | 2.91874635 |
| 14 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.90262025 |
| 15 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 2.45092074 |
| 16 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 2.38238446 |
| 17 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 2.26632318 |
| 18 | CIITA_25753668_ChIP-Seq_RAJI_Human | 2.24094988 |
| 19 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.11370511 |
| 20 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.10831307 |
| 21 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 2.06252869 |
| 22 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.06228086 |
| 23 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.96575051 |
| 24 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.93667350 |
| 25 | EWS_26573619_Chip-Seq_HEK293_Human | 1.86894702 |
| 26 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.78354801 |
| 27 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.75384117 |
| 28 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.74366497 |
| 29 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 1.73439170 |
| 30 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.72183949 |
| 31 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.70890041 |
| 32 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.63549037 |
| 33 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.61770903 |
| 34 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.59844699 |
| 35 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.57405724 |
| 36 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.55304002 |
| 37 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 1.53946243 |
| 38 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 1.51521247 |
| 39 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.46774111 |
| 40 | FUS_26573619_Chip-Seq_HEK293_Human | 1.44413921 |
| 41 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.43639519 |
| 42 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 1.42333494 |
| 43 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.41471915 |
| 44 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.39906708 |
| 45 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.37211731 |
| 46 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 1.34577986 |
| 47 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.33892165 |
| 48 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 1.31012125 |
| 49 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.30726730 |
| 50 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.27704567 |
| 51 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.26400975 |
| 52 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.24908550 |
| 53 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.19571909 |
| 54 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.17203824 |
| 55 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.17203824 |
| 56 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.17186065 |
| 57 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.15390201 |
| 58 | PPARD_23208498_ChIP-Seq_MDA-MB-231_Human | 1.15087018 |
| 59 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 1.15071578 |
| 60 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.13989257 |
| 61 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.12262499 |
| 62 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.11934973 |
| 63 | GATA3_26560356_Chip-Seq_TH2_Human | 1.11655354 |
| 64 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.10308267 |
| 65 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.10261955 |
| 66 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.09583385 |
| 67 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 1.09125386 |
| 68 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.08703407 |
| 69 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.08703407 |
| 70 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.08326374 |
| 71 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.08104332 |
| 72 | ERG_20517297_ChIP-Seq_VCAP_Human | 1.07574332 |
| 73 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 1.07469111 |
| 74 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.06879319 |
| 75 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.05673725 |
| 76 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.05236376 |
| 77 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.04499170 |
| 78 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.01956968 |
| 79 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 0.99498889 |
| 80 | NANOG_19829295_ChIP-Seq_ESCs_Human | 0.98591072 |
| 81 | SOX2_19829295_ChIP-Seq_ESCs_Human | 0.98591072 |
| 82 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 0.97219360 |
| 83 | FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.97102651 |
| 84 | NCOR_22424771_ChIP-Seq_293T_Human | 0.95552991 |
| 85 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 0.94248019 |
| 86 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 0.94024529 |
| 87 | AR_21572438_ChIP-Seq_LNCaP_Human | 0.93032413 |
| 88 | SPI1_23547873_ChIP-Seq_NB4_Human | 0.92343045 |
| 89 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 0.91980012 |
| 90 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 0.91898596 |
| 91 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 0.89814582 |
| 92 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 0.88781917 |
| 93 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 0.88392919 |
| 94 | BCL3_23251550_ChIP-Seq_MUSCLE_Mouse | 0.88164597 |
| 95 | CRX_20693478_ChIP-Seq_RETINA_Mouse | 0.86987120 |
| 96 | HOXB7_26014856_ChIP-Seq_BT474_Human | 0.84792119 |
| 97 | P300_19829295_ChIP-Seq_ESCs_Human | 0.83069534 |
| 98 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 0.82856898 |
| 99 | AR_20517297_ChIP-Seq_VCAP_Human | 0.82722442 |
| 100 | XRN2_22483619_ChIP-Seq_HELA_Human | 0.82317843 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0001835_abnormal_antigen_presentation | 3.37132473 |
| 2 | MP0005084_abnormal_gallbladder_morpholo | 3.22677707 |
| 3 | MP0001529_abnormal_vocalization | 3.15851958 |
| 4 | MP0002102_abnormal_ear_morphology | 2.87927914 |
| 5 | MP0002736_abnormal_nociception_after | 2.86741503 |
| 6 | MP0005645_abnormal_hypothalamus_physiol | 2.64334454 |
| 7 | MP0000569_abnormal_digit_pigmentation | 2.50758333 |
| 8 | MP0001905_abnormal_dopamine_level | 2.46750780 |
| 9 | MP0004145_abnormal_muscle_electrophysio | 2.37781541 |
| 10 | MP0001986_abnormal_taste_sensitivity | 2.36615996 |
| 11 | MP0003283_abnormal_digestive_organ | 2.31250620 |
| 12 | MP0002138_abnormal_hepatobiliary_system | 2.29218575 |
| 13 | MP0003806_abnormal_nucleotide_metabolis | 2.27829038 |
| 14 | MP0009785_altered_susceptibility_to | 2.18953484 |
| 15 | MP0006036_abnormal_mitochondrial_physio | 2.11600152 |
| 16 | MP0008875_abnormal_xenobiotic_pharmacok | 2.08423413 |
| 17 | MP0005083_abnormal_biliary_tract | 2.06617859 |
| 18 | MP0001968_abnormal_touch/_nociception | 2.02034158 |
| 19 | MP0000685_abnormal_immune_system | 1.93883202 |
| 20 | MP0002148_abnormal_hypersensitivity_rea | 1.93307456 |
| 21 | MP0002160_abnormal_reproductive_system | 1.91372492 |
| 22 | MP0002837_dystrophic_cardiac_calcinosis | 1.90545745 |
| 23 | MP0006035_abnormal_mitochondrial_morpho | 1.74642486 |
| 24 | MP0008872_abnormal_physiological_respon | 1.74235665 |
| 25 | MP0001800_abnormal_humoral_immune | 1.67312403 |
| 26 | MP0002822_catalepsy | 1.50356198 |
| 27 | MP0001188_hyperpigmentation | 1.46190083 |
| 28 | MP0005671_abnormal_response_to | 1.44635839 |
| 29 | MP0002735_abnormal_chemical_nociception | 1.44574912 |
| 30 | MP0003786_premature_aging | 1.43663126 |
| 31 | MP0005389_reproductive_system_phenotype | 1.41748144 |
| 32 | MP0004142_abnormal_muscle_tone | 1.38983730 |
| 33 | MP0002166_altered_tumor_susceptibility | 1.38600208 |
| 34 | MP0005000_abnormal_immune_tolerance | 1.32235639 |
| 35 | MP0008058_abnormal_DNA_repair | 1.31724655 |
| 36 | MP0006054_spinal_hemorrhage | 1.31084939 |
| 37 | MP0008789_abnormal_olfactory_epithelium | 1.30151840 |
| 38 | MP0005165_increased_susceptibility_to | 1.27808995 |
| 39 | MP0005360_urolithiasis | 1.27774082 |
| 40 | MP0003186_abnormal_redox_activity | 1.25016108 |
| 41 | MP0005551_abnormal_eye_electrophysiolog | 1.24919691 |
| 42 | MP0002723_abnormal_immune_serum | 1.21661723 |
| 43 | MP0002452_abnormal_antigen_presenting | 1.21585900 |
| 44 | MP0001542_abnormal_bone_strength | 1.20170100 |
| 45 | MP0002234_abnormal_pharynx_morphology | 1.17173149 |
| 46 | MP0001790_abnormal_immune_system | 1.16709268 |
| 47 | MP0005387_immune_system_phenotype | 1.16709268 |
| 48 | MP0001919_abnormal_reproductive_system | 1.15807693 |
| 49 | MP0004215_abnormal_myocardial_fiber | 1.13493959 |
| 50 | MP0002733_abnormal_thermal_nociception | 1.12068140 |
| 51 | MP0010094_abnormal_chromosome_stability | 1.08414030 |
| 52 | MP0002006_tumorigenesis | 1.06856170 |
| 53 | MP0001756_abnormal_urination | 1.05049779 |
| 54 | MP0009053_abnormal_anal_canal | 1.03239666 |
| 55 | MP0002420_abnormal_adaptive_immunity | 1.01811536 |
| 56 | MP0004084_abnormal_cardiac_muscle | 1.01610733 |
| 57 | MP0001819_abnormal_immune_cell | 1.00243817 |
| 58 | MP0009764_decreased_sensitivity_to | 0.99597060 |
| 59 | MP0009745_abnormal_behavioral_response | 0.98082046 |
| 60 | MP0000015_abnormal_ear_pigmentation | 0.95370591 |
| 61 | MP0001984_abnormal_olfaction | 0.94690775 |
| 62 | MP0003938_abnormal_ear_development | 0.92947516 |
| 63 | MP0010155_abnormal_intestine_physiology | 0.92837405 |
| 64 | MP0005025_abnormal_response_to | 0.92438083 |
| 65 | MP0002272_abnormal_nervous_system | 0.90823572 |
| 66 | MP0005410_abnormal_fertilization | 0.89437657 |
| 67 | MP0003763_abnormal_thymus_physiology | 0.88831805 |
| 68 | MP0000689_abnormal_spleen_morphology | 0.88071448 |
| 69 | MP0006292_abnormal_olfactory_placode | 0.87330805 |
| 70 | MP0005332_abnormal_amino_acid | 0.86923474 |
| 71 | MP0004147_increased_porphyrin_level | 0.85914032 |
| 72 | MP0005310_abnormal_salivary_gland | 0.84447832 |
| 73 | MP0003137_abnormal_impulse_conducting | 0.84253028 |
| 74 | MP0002734_abnormal_mechanical_nocicepti | 0.83576636 |
| 75 | MP0001970_abnormal_pain_threshold | 0.83544926 |
| 76 | MP0005464_abnormal_platelet_physiology | 0.82084175 |
| 77 | MP0002572_abnormal_emotion/affect_behav | 0.82039302 |
| 78 | MP0009333_abnormal_splenocyte_physiolog | 0.81608371 |
| 79 | MP0008932_abnormal_embryonic_tissue | 0.81142407 |
| 80 | MP0005174_abnormal_tail_pigmentation | 0.80797711 |
| 81 | MP0000358_abnormal_cell_content/ | 0.78342900 |
| 82 | MP0000716_abnormal_immune_system | 0.78005211 |
| 83 | MP0004957_abnormal_blastocyst_morpholog | 0.77864344 |
| 84 | MP0003866_abnormal_defecation | 0.74251879 |
| 85 | MP0002638_abnormal_pupillary_reflex | 0.73939122 |
| 86 | MP0005167_abnormal_blood-brain_barrier | 0.73663307 |
| 87 | MP0000613_abnormal_salivary_gland | 0.73273982 |
| 88 | MP0009046_muscle_twitch | 0.73014491 |
| 89 | MP0001764_abnormal_homeostasis | 0.72888155 |
| 90 | MP0008873_increased_physiological_sensi | 0.71905669 |
| 91 | MP0002398_abnormal_bone_marrow | 0.71782121 |
| 92 | MP0004742_abnormal_vestibular_system | 0.70489957 |
| 93 | MP0000516_abnormal_urinary_system | 0.70230708 |
| 94 | MP0005367_renal/urinary_system_phenotyp | 0.70230708 |
| 95 | MP0004885_abnormal_endolymph | 0.70104614 |
| 96 | MP0000749_muscle_degeneration | 0.68799008 |
| 97 | MP0004133_heterotaxia | 0.68745908 |
| 98 | MP0002419_abnormal_innate_immunity | 0.68672916 |
| 99 | MP0001243_abnormal_dermal_layer | 0.67918168 |
| 100 | MP0009643_abnormal_urine_homeostasis | 0.66066079 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Acute necrotizing encephalopathy (HP:0006965) | 5.51415829 |
| 2 | Abnormal mitochondria in muscle tissue (HP:0008316) | 4.82402243 |
| 3 | Mitochondrial inheritance (HP:0001427) | 4.80530728 |
| 4 | Progressive macrocephaly (HP:0004481) | 4.67051329 |
| 5 | Increased CSF lactate (HP:0002490) | 4.39683508 |
| 6 | Acute encephalopathy (HP:0006846) | 4.28751663 |
| 7 | Opisthotonus (HP:0002179) | 4.25989890 |
| 8 | Hepatocellular necrosis (HP:0001404) | 3.86612928 |
| 9 | Renal cortical cysts (HP:0000803) | 3.69564278 |
| 10 | Cerebral edema (HP:0002181) | 3.64904468 |
| 11 | 3-Methylglutaconic aciduria (HP:0003535) | 3.60362661 |
| 12 | Tubulointerstitial nephritis (HP:0001970) | 3.42171911 |
| 13 | Hepatic necrosis (HP:0002605) | 3.41999584 |
| 14 | Increased hepatocellular lipid droplets (HP:0006565) | 3.25191821 |
| 15 | Increased serum lactate (HP:0002151) | 3.02116797 |
| 16 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 3.01490693 |
| 17 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 3.01490693 |
| 18 | Lactic acidosis (HP:0003128) | 2.99881394 |
| 19 | Microvesicular hepatic steatosis (HP:0001414) | 2.99270967 |
| 20 | Elevated erythrocyte sedimentation rate (HP:0003565) | 2.99011864 |
| 21 | Respiratory failure (HP:0002878) | 2.98330926 |
| 22 | Mesangial abnormality (HP:0001966) | 2.93240668 |
| 23 | Lipid accumulation in hepatocytes (HP:0006561) | 2.93088630 |
| 24 | Renal Fanconi syndrome (HP:0001994) | 2.92784348 |
| 25 | Optic disc pallor (HP:0000543) | 2.63353439 |
| 26 | Increased serum pyruvate (HP:0003542) | 2.62093447 |
| 27 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 2.57699009 |
| 28 | Abnormality of alanine metabolism (HP:0010916) | 2.57699009 |
| 29 | Hyperalaninemia (HP:0003348) | 2.57699009 |
| 30 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 2.55569274 |
| 31 | Absent/shortened dynein arms (HP:0200106) | 2.55569274 |
| 32 | Exertional dyspnea (HP:0002875) | 2.49558988 |
| 33 | Progressive microcephaly (HP:0000253) | 2.48462229 |
| 34 | Exercise intolerance (HP:0003546) | 2.44832839 |
| 35 | Leukodystrophy (HP:0002415) | 2.42649524 |
| 36 | Abnormality of the renal cortex (HP:0011035) | 2.40757267 |
| 37 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.38623050 |
| 38 | Congenital stationary night blindness (HP:0007642) | 2.38122542 |
| 39 | Increased intramyocellular lipid droplets (HP:0012240) | 2.25831555 |
| 40 | Nausea (HP:0002018) | 2.24628227 |
| 41 | True hermaphroditism (HP:0010459) | 2.19967264 |
| 42 | Xerostomia (HP:0000217) | 2.19833427 |
| 43 | Entropion (HP:0000621) | 2.15425697 |
| 44 | Methylmalonic acidemia (HP:0002912) | 2.15092304 |
| 45 | Tubulointerstitial abnormality (HP:0001969) | 2.13890465 |
| 46 | Delayed CNS myelination (HP:0002188) | 2.12486908 |
| 47 | Methylmalonic aciduria (HP:0012120) | 2.12006988 |
| 48 | Hyperphosphaturia (HP:0003109) | 2.11662806 |
| 49 | Panhypogammaglobulinemia (HP:0003139) | 2.11038220 |
| 50 | Shoulder girdle muscle weakness (HP:0003547) | 2.11012354 |
| 51 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 2.10568987 |
| 52 | Pancreatic cysts (HP:0001737) | 2.09154611 |
| 53 | Abnormality of macular pigmentation (HP:0008002) | 2.08714122 |
| 54 | Pulmonary infiltrates (HP:0002113) | 2.08636089 |
| 55 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 2.08536702 |
| 56 | Tinnitus (HP:0000360) | 2.04782583 |
| 57 | Lethargy (HP:0001254) | 2.03555471 |
| 58 | Abnormality of long-chain fatty-acid metabolism (HP:0010964) | 2.03483427 |
| 59 | Brushfield spots (HP:0001088) | 2.02174878 |
| 60 | Gonadotropin excess (HP:0000837) | 2.01904415 |
| 61 | Poor suck (HP:0002033) | 2.00001448 |
| 62 | CNS demyelination (HP:0007305) | 1.98855705 |
| 63 | Redundant skin (HP:0001582) | 1.98499056 |
| 64 | Abnormality of glycolysis (HP:0004366) | 1.97562568 |
| 65 | Prominent metopic ridge (HP:0005487) | 1.94241547 |
| 66 | Hepatosplenomegaly (HP:0001433) | 1.94123003 |
| 67 | Abnormal protein N-linked glycosylation (HP:0012347) | 1.93286804 |
| 68 | Abnormal protein glycosylation (HP:0012346) | 1.93286804 |
| 69 | Abnormal glycosylation (HP:0012345) | 1.93286804 |
| 70 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 1.93286804 |
| 71 | X-linked dominant inheritance (HP:0001423) | 1.90574883 |
| 72 | Abnormality of lateral ventricle (HP:0030047) | 1.90300185 |
| 73 | Hypoproteinemia (HP:0003075) | 1.89247197 |
| 74 | Abnormality of dicarboxylic acid metabolism (HP:0010995) | 1.88127439 |
| 75 | Dicarboxylic aciduria (HP:0003215) | 1.88127439 |
| 76 | Congenital, generalized hypertrichosis (HP:0004540) | 1.86895230 |
| 77 | Poor head control (HP:0002421) | 1.86544180 |
| 78 | Volvulus (HP:0002580) | 1.85966323 |
| 79 | Rhabdomyolysis (HP:0003201) | 1.83905436 |
| 80 | Type I transferrin isoform profile (HP:0003642) | 1.83142197 |
| 81 | Stomatitis (HP:0010280) | 1.83004826 |
| 82 | Lissencephaly (HP:0001339) | 1.82505028 |
| 83 | Pancreatic fibrosis (HP:0100732) | 1.82093198 |
| 84 | Medial flaring of the eyebrow (HP:0010747) | 1.80463239 |
| 85 | Dyschromatopsia (HP:0007641) | 1.77850031 |
| 86 | Abnormality of purine metabolism (HP:0004352) | 1.77449302 |
| 87 | Congenital nonbullous ichthyosiform erythroderma (HP:0007479) | 1.77211699 |
| 88 | Abnormality of the metopic suture (HP:0005556) | 1.75105271 |
| 89 | Increased muscle lipid content (HP:0009058) | 1.73032926 |
| 90 | Abnormality of renal resorption (HP:0011038) | 1.72734672 |
| 91 | Abnormal respiratory motile cilium morphology (HP:0005938) | 1.71029653 |
| 92 | Abnormal respiratory epithelium morphology (HP:0012253) | 1.71029653 |
| 93 | Limb dystonia (HP:0002451) | 1.69899787 |
| 94 | Oral leukoplakia (HP:0002745) | 1.68509697 |
| 95 | Inability to walk (HP:0002540) | 1.67011170 |
| 96 | Pelvic girdle muscle weakness (HP:0003749) | 1.66851147 |
| 97 | Central scotoma (HP:0000603) | 1.66766615 |
| 98 | Primary adrenal insufficiency (HP:0008207) | 1.66582200 |
| 99 | Abolished electroretinogram (ERG) (HP:0000550) | 1.65510162 |
| 100 | Postaxial foot polydactyly (HP:0001830) | 1.65273207 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MAP4K2 | 5.67316036 |
| 2 | RIPK4 | 3.02763829 |
| 3 | TSSK6 | 3.00945641 |
| 4 | BCKDK | 2.72190662 |
| 5 | MST4 | 2.54502871 |
| 6 | NEK1 | 2.50753717 |
| 7 | EIF2AK3 | 2.44294722 |
| 8 | PIM2 | 2.37680306 |
| 9 | PHKG1 | 2.25382704 |
| 10 | PHKG2 | 2.25382704 |
| 11 | TLK1 | 2.23146271 |
| 12 | VRK2 | 2.18721905 |
| 13 | WNK3 | 1.91749807 |
| 14 | KIT | 1.87876253 |
| 15 | TEC | 1.85048384 |
| 16 | EIF2AK1 | 1.84382964 |
| 17 | NUAK1 | 1.70020804 |
| 18 | PDK2 | 1.58576565 |
| 19 | PBK | 1.57771663 |
| 20 | TAOK3 | 1.56413580 |
| 21 | PLK2 | 1.45989100 |
| 22 | PIK3CG | 1.41358683 |
| 23 | BCR | 1.34866625 |
| 24 | NME2 | 1.33834501 |
| 25 | MAP3K12 | 1.31560466 |
| 26 | ADRBK2 | 1.22987306 |
| 27 | ITK | 1.20920286 |
| 28 | SYK | 1.19380646 |
| 29 | MAPK13 | 1.18193027 |
| 30 | BUB1 | 1.16001464 |
| 31 | DYRK2 | 1.15569965 |
| 32 | TNIK | 1.15535548 |
| 33 | MARK1 | 1.13903825 |
| 34 | IKBKB | 1.13790079 |
| 35 | MKNK1 | 1.12830601 |
| 36 | NEK9 | 1.10815170 |
| 37 | EIF2AK2 | 1.10217943 |
| 38 | CSNK1G3 | 1.08244376 |
| 39 | VRK1 | 1.06042932 |
| 40 | OXSR1 | 1.06013593 |
| 41 | ALK | 1.04969889 |
| 42 | CSNK1A1L | 1.02437203 |
| 43 | BMPR1B | 1.00219195 |
| 44 | GRK6 | 0.99922196 |
| 45 | MAPKAPK5 | 0.98176254 |
| 46 | TXK | 0.98079858 |
| 47 | CCNB1 | 0.91147452 |
| 48 | INSRR | 0.91134173 |
| 49 | MAPKAPK3 | 0.89911908 |
| 50 | JAK3 | 0.85219219 |
| 51 | BMPR2 | 0.82578585 |
| 52 | GRK1 | 0.82455436 |
| 53 | ARAF | 0.81523545 |
| 54 | ZAK | 0.78925055 |
| 55 | DAPK1 | 0.74877916 |
| 56 | TAF1 | 0.72093275 |
| 57 | CSNK1G2 | 0.71966573 |
| 58 | PLK3 | 0.71369339 |
| 59 | PRKCI | 0.71242470 |
| 60 | TAOK2 | 0.68863501 |
| 61 | TIE1 | 0.68765507 |
| 62 | MAP2K6 | 0.68151269 |
| 63 | RPS6KA5 | 0.66648840 |
| 64 | IKBKE | 0.62609762 |
| 65 | MAP3K4 | 0.62241486 |
| 66 | TRIM28 | 0.62033451 |
| 67 | SCYL2 | 0.61588468 |
| 68 | KDR | 0.60523094 |
| 69 | ABL2 | 0.57028932 |
| 70 | BTK | 0.57010759 |
| 71 | CSNK1G1 | 0.52541741 |
| 72 | CDK19 | 0.52503438 |
| 73 | MAP2K7 | 0.51647147 |
| 74 | TBK1 | 0.51617994 |
| 75 | MYLK | 0.51325943 |
| 76 | AKT3 | 0.50672791 |
| 77 | PRKCE | 0.50101907 |
| 78 | MAP3K3 | 0.49914246 |
| 79 | TGFBR1 | 0.49712873 |
| 80 | PASK | 0.48544133 |
| 81 | TYK2 | 0.48542840 |
| 82 | MAP3K11 | 0.47848359 |
| 83 | OBSCN | 0.47685096 |
| 84 | PRKCQ | 0.46672871 |
| 85 | MAPK15 | 0.45999593 |
| 86 | MAP2K3 | 0.45993737 |
| 87 | PRKCG | 0.44002206 |
| 88 | STK16 | 0.43767897 |
| 89 | STK39 | 0.43521690 |
| 90 | GRK5 | 0.41380309 |
| 91 | CASK | 0.40597692 |
| 92 | LYN | 0.40439352 |
| 93 | MAPK4 | 0.39419833 |
| 94 | ABL1 | 0.38342401 |
| 95 | CAMK2A | 0.38204162 |
| 96 | IGF1R | 0.37914661 |
| 97 | PAK3 | 0.37782114 |
| 98 | FES | 0.34736254 |
| 99 | LCK | 0.33709481 |
| 100 | FRK | 0.30929182 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Proteasome_Homo sapiens_hsa03050 | 5.26215056 |
| 2 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 4.19218620 |
| 3 | Parkinsons disease_Homo sapiens_hsa05012 | 3.70938470 |
| 4 | Protein export_Homo sapiens_hsa03060 | 2.99317621 |
| 5 | Alzheimers disease_Homo sapiens_hsa05010 | 2.40166330 |
| 6 | Huntingtons disease_Homo sapiens_hsa05016 | 2.37883836 |
| 7 | Sulfur relay system_Homo sapiens_hsa04122 | 2.17915007 |
| 8 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.99090548 |
| 9 | Asthma_Homo sapiens_hsa05310 | 1.93778147 |
| 10 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.93611931 |
| 11 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.89693267 |
| 12 | RNA degradation_Homo sapiens_hsa03018 | 1.85680215 |
| 13 | Sulfur metabolism_Homo sapiens_hsa00920 | 1.85629991 |
| 14 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.76660223 |
| 15 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.76163231 |
| 16 | Ribosome_Homo sapiens_hsa03010 | 1.73889897 |
| 17 | RNA polymerase_Homo sapiens_hsa03020 | 1.67448294 |
| 18 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.63945796 |
| 19 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.60379431 |
| 20 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.52192878 |
| 21 | Allograft rejection_Homo sapiens_hsa05330 | 1.50667753 |
| 22 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.45076034 |
| 23 | DNA replication_Homo sapiens_hsa03030 | 1.42407009 |
| 24 | Fatty acid elongation_Homo sapiens_hsa00062 | 1.41982752 |
| 25 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.40913301 |
| 26 | Homologous recombination_Homo sapiens_hsa03440 | 1.40597327 |
| 27 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.40326412 |
| 28 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 1.38214424 |
| 29 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 1.37786230 |
| 30 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.36066268 |
| 31 | Purine metabolism_Homo sapiens_hsa00230 | 1.35817258 |
| 32 | Peroxisome_Homo sapiens_hsa04146 | 1.33128906 |
| 33 | Folate biosynthesis_Homo sapiens_hsa00790 | 1.32988229 |
| 34 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.31569160 |
| 35 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 1.29972665 |
| 36 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.23957689 |
| 37 | Mismatch repair_Homo sapiens_hsa03430 | 1.22625243 |
| 38 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.20667975 |
| 39 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.11402085 |
| 40 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 1.10040711 |
| 41 | Basal transcription factors_Homo sapiens_hsa03022 | 1.07507078 |
| 42 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.03333786 |
| 43 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.98755731 |
| 44 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.98435309 |
| 45 | Spliceosome_Homo sapiens_hsa03040 | 0.97547459 |
| 46 | Renin-angiotensin system_Homo sapiens_hsa04614 | 0.96994684 |
| 47 | Phototransduction_Homo sapiens_hsa04744 | 0.92613213 |
| 48 | Base excision repair_Homo sapiens_hsa03410 | 0.91296049 |
| 49 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.90829881 |
| 50 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.88901928 |
| 51 | Viral myocarditis_Homo sapiens_hsa05416 | 0.88500740 |
| 52 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.88205278 |
| 53 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 0.86689742 |
| 54 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.85624931 |
| 55 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.84940959 |
| 56 | RNA transport_Homo sapiens_hsa03013 | 0.83770794 |
| 57 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.78756248 |
| 58 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.76253091 |
| 59 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.73813215 |
| 60 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.72782671 |
| 61 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.70658319 |
| 62 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.70255676 |
| 63 | Metabolic pathways_Homo sapiens_hsa01100 | 0.69310097 |
| 64 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.68011237 |
| 65 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.67814492 |
| 66 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.66565313 |
| 67 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.65270620 |
| 68 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.64573361 |
| 69 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.61465417 |
| 70 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.58522270 |
| 71 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.56183445 |
| 72 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.55974707 |
| 73 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.55527957 |
| 74 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.54802776 |
| 75 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.54273606 |
| 76 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.51969597 |
| 77 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.50785983 |
| 78 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.48719573 |
| 79 | Shigellosis_Homo sapiens_hsa05131 | 0.45243502 |
| 80 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.43555064 |
| 81 | Nicotine addiction_Homo sapiens_hsa05033 | 0.43104396 |
| 82 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.41930513 |
| 83 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.41640743 |
| 84 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.40149946 |
| 85 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.39431131 |
| 86 | Phagosome_Homo sapiens_hsa04145 | 0.39187033 |
| 87 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.37789629 |
| 88 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.34203070 |
| 89 | Morphine addiction_Homo sapiens_hsa05032 | 0.32502551 |
| 90 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.31458943 |
| 91 | Retinol metabolism_Homo sapiens_hsa00830 | 0.31326953 |
| 92 | Legionellosis_Homo sapiens_hsa05134 | 0.31289523 |
| 93 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.30012785 |
| 94 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.29092944 |
| 95 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.28511621 |
| 96 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.27464976 |
| 97 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.27042443 |
| 98 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.25159511 |
| 99 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.24228918 |
| 100 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.23220188 |

