

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | preassembly of GPI anchor in ER membrane (GO:0016254) | 6.12601535 |
| 2 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 5.23859800 |
| 3 | ATP synthesis coupled proton transport (GO:0015986) | 5.23859800 |
| 4 | DNA deamination (GO:0045006) | 4.89044921 |
| 5 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 4.65741048 |
| 6 | mannosylation (GO:0097502) | 4.60725561 |
| 7 | GPI anchor metabolic process (GO:0006505) | 4.23679602 |
| 8 | C-terminal protein amino acid modification (GO:0018410) | 4.23289535 |
| 9 | GPI anchor biosynthetic process (GO:0006506) | 4.13818340 |
| 10 | C-terminal protein lipidation (GO:0006501) | 4.00761331 |
| 11 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 3.96334225 |
| 12 | xenobiotic catabolic process (GO:0042178) | 3.90982102 |
| 13 | water-soluble vitamin biosynthetic process (GO:0042364) | 3.89658511 |
| 14 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 3.85763505 |
| 15 | regulation of cellular amino acid metabolic process (GO:0006521) | 3.75570648 |
| 16 | cullin deneddylation (GO:0010388) | 3.71308205 |
| 17 | iron-sulfur cluster assembly (GO:0016226) | 3.70414018 |
| 18 | metallo-sulfur cluster assembly (GO:0031163) | 3.70414018 |
| 19 | positive regulation of prostaglandin secretion (GO:0032308) | 3.69590781 |
| 20 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 3.63491787 |
| 21 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 3.63491787 |
| 22 | meiotic chromosome segregation (GO:0045132) | 3.63344599 |
| 23 | detection of light stimulus involved in visual perception (GO:0050908) | 3.58203920 |
| 24 | detection of light stimulus involved in sensory perception (GO:0050962) | 3.58203920 |
| 25 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 3.56741420 |
| 26 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 3.56741420 |
| 27 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 3.56741420 |
| 28 | GTP biosynthetic process (GO:0006183) | 3.56622467 |
| 29 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 3.55574405 |
| 30 | negative regulation of hematopoietic progenitor cell differentiation (GO:1901533) | 3.48512961 |
| 31 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 3.45812554 |
| 32 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 3.45812554 |
| 33 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 3.41477394 |
| 34 | protein complex biogenesis (GO:0070271) | 3.40839522 |
| 35 | proteasome assembly (GO:0043248) | 3.38250014 |
| 36 | endothelial tube morphogenesis (GO:0061154) | 3.32858384 |
| 37 | morphogenesis of an endothelium (GO:0003159) | 3.32858384 |
| 38 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 3.27043626 |
| 39 | DNA replication-dependent nucleosome assembly (GO:0006335) | 3.26878379 |
| 40 | DNA replication-dependent nucleosome organization (GO:0034723) | 3.26878379 |
| 41 | glial cell proliferation (GO:0014009) | 3.26753032 |
| 42 | regulation of prostaglandin secretion (GO:0032306) | 3.24277117 |
| 43 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.18813871 |
| 44 | protein neddylation (GO:0045116) | 3.18151186 |
| 45 | NIK/NF-kappaB signaling (GO:0038061) | 3.14940746 |
| 46 | purine nucleoside triphosphate biosynthetic process (GO:0009145) | 3.12510701 |
| 47 | purine ribonucleoside triphosphate biosynthetic process (GO:0009206) | 3.11897449 |
| 48 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 3.06004751 |
| 49 | establishment of viral latency (GO:0019043) | 3.02425933 |
| 50 | UTP biosynthetic process (GO:0006228) | 3.01218035 |
| 51 | somite development (GO:0061053) | 3.00775133 |
| 52 | ATP biosynthetic process (GO:0006754) | 2.97773760 |
| 53 | behavioral response to ethanol (GO:0048149) | 2.97215480 |
| 54 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 2.96821276 |
| 55 | energy coupled proton transmembrane transport, against electrochemical gradient (GO:0015988) | 2.96775020 |
| 56 | ATP hydrolysis coupled proton transport (GO:0015991) | 2.96775020 |
| 57 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 2.94851138 |
| 58 | respiratory electron transport chain (GO:0022904) | 2.92663235 |
| 59 | regulation of transmission of nerve impulse (GO:0051969) | 2.92419945 |
| 60 | establishment of integrated proviral latency (GO:0075713) | 2.92404401 |
| 61 | electron transport chain (GO:0022900) | 2.90765730 |
| 62 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 2.90076655 |
| 63 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 2.90076655 |
| 64 | NADH dehydrogenase complex assembly (GO:0010257) | 2.90076655 |
| 65 | protein deneddylation (GO:0000338) | 2.89902944 |
| 66 | indolalkylamine metabolic process (GO:0006586) | 2.89152036 |
| 67 | pentose metabolic process (GO:0019321) | 2.88002332 |
| 68 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 2.87957063 |
| 69 | negative regulation of ligase activity (GO:0051352) | 2.87957063 |
| 70 | protein localization to cilium (GO:0061512) | 2.86267754 |
| 71 | regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway (GO:0039531) | 2.84080073 |
| 72 | regulation of RIG-I signaling pathway (GO:0039535) | 2.81565181 |
| 73 | mitotic cell cycle arrest (GO:0071850) | 2.81054406 |
| 74 | mismatch repair (GO:0006298) | 2.80075121 |
| 75 | retina homeostasis (GO:0001895) | 2.80016307 |
| 76 | guanosine-containing compound biosynthetic process (GO:1901070) | 2.78725061 |
| 77 | positive regulation of ligase activity (GO:0051351) | 2.77748372 |
| 78 | cornea development in camera-type eye (GO:0061303) | 2.77519285 |
| 79 | positive regulation of ubiquitin-protein transferase activity (GO:0051443) | 2.76151304 |
| 80 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 2.75490471 |
| 81 | termination of RNA polymerase III transcription (GO:0006386) | 2.75490471 |
| 82 | hydrogen ion transmembrane transport (GO:1902600) | 2.74839209 |
| 83 | UTP metabolic process (GO:0046051) | 2.74611949 |
| 84 | glycolipid biosynthetic process (GO:0009247) | 2.74554473 |
| 85 | DNA ligation (GO:0006266) | 2.73933878 |
| 86 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 2.71587756 |
| 87 | neuronal action potential (GO:0019228) | 2.71221851 |
| 88 | ribonucleoside triphosphate biosynthetic process (GO:0009201) | 2.68059036 |
| 89 | DNA damage response, signal transduction by p53 class mediator (GO:0030330) | 2.67816244 |
| 90 | respiratory chain complex IV assembly (GO:0008535) | 2.67762740 |
| 91 | regulation of cellular amine metabolic process (GO:0033238) | 2.63858000 |
| 92 | limb bud formation (GO:0060174) | 2.63852665 |
| 93 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO: | 2.62675584 |
| 94 | DNA catabolic process, exonucleolytic (GO:0000738) | 2.62146093 |
| 95 | hydrogen transport (GO:0006818) | 2.61655653 |
| 96 | proton transport (GO:0015992) | 2.61271784 |
| 97 | replicative senescence (GO:0090399) | 2.61117695 |
| 98 | vitamin biosynthetic process (GO:0009110) | 2.61013489 |
| 99 | sequestering of actin monomers (GO:0042989) | 2.60993028 |
| 100 | fat-soluble vitamin catabolic process (GO:0042363) | 2.59637493 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 9.12142274 |
| 2 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 4.04384545 |
| 3 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 3.97028127 |
| 4 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 3.48479443 |
| 5 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 3.10284047 |
| 6 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 2.97089170 |
| 7 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 2.96585347 |
| 8 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.78729857 |
| 9 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 2.71622308 |
| 10 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.64609228 |
| 11 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.58648286 |
| 12 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 2.54656492 |
| 13 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 2.54327399 |
| 14 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.47661822 |
| 15 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.37535245 |
| 16 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.36847696 |
| 17 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 2.32735230 |
| 18 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 2.29365814 |
| 19 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 2.04109508 |
| 20 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 2.02679365 |
| 21 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.89205704 |
| 22 | VDR_22108803_ChIP-Seq_LS180_Human | 1.86913704 |
| 23 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.82850767 |
| 24 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 1.77491163 |
| 25 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.74440009 |
| 26 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.72392682 |
| 27 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.70359333 |
| 28 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.60665260 |
| 29 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 1.60112940 |
| 30 | PPARD_23208498_ChIP-Seq_MDA-MB-231_Human | 1.54067982 |
| 31 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.50703358 |
| 32 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.50100587 |
| 33 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.50057996 |
| 34 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 1.49178242 |
| 35 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.46342562 |
| 36 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.42427073 |
| 37 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.38562058 |
| 38 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.37495182 |
| 39 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.36940473 |
| 40 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.33531530 |
| 41 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.32134005 |
| 42 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.28873208 |
| 43 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.28202063 |
| 44 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.25797104 |
| 45 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 1.25372489 |
| 46 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.24015865 |
| 47 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.22249496 |
| 48 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.19464743 |
| 49 | EWS_26573619_Chip-Seq_HEK293_Human | 1.17984115 |
| 50 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 1.17956115 |
| 51 | SOX2_16153702_ChIP-ChIP_HESCs_Human | 1.16427615 |
| 52 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.15679017 |
| 53 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.12808631 |
| 54 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 1.12486868 |
| 55 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.11727504 |
| 56 | GBX2_23144817_ChIP-Seq_PC3_Human | 1.09365391 |
| 57 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.08814470 |
| 58 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.07838592 |
| 59 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.07769270 |
| 60 | ESR1_15608294_ChIP-ChIP_MCF-7_Human | 1.07613147 |
| 61 | NCOR_22424771_ChIP-Seq_293T_Human | 1.06950058 |
| 62 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.05985814 |
| 63 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.04663300 |
| 64 | RNF2_16625203_ChIP-ChIP_MESCs_Mouse | 1.04089904 |
| 65 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.03855644 |
| 66 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 1.03688003 |
| 67 | SMAD1_18555785_ChIP-Seq_MESCs_Mouse | 1.03157085 |
| 68 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 0.99908885 |
| 69 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 0.99839887 |
| 70 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 0.98782967 |
| 71 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 0.97904667 |
| 72 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 0.97904667 |
| 73 | CBP_20019798_ChIP-Seq_JUKART_Human | 0.95556561 |
| 74 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 0.95556561 |
| 75 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 0.95357803 |
| 76 | EBNA1_20929547_Chip-Seq_RAJI-cells_Human | 0.94936657 |
| 77 | IGF1R_20145208_ChIP-Seq_DFB_Human | 0.93495487 |
| 78 | FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse | 0.93274376 |
| 79 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 0.92599363 |
| 80 | ELF1_20517297_ChIP-Seq_JURKAT_Human | 0.91600214 |
| 81 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 0.90789521 |
| 82 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 0.90035224 |
| 83 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 0.89870678 |
| 84 | CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human | 0.89377085 |
| 85 | ATF3_23680149_ChIP-Seq_GBM1-GSC_Human | 0.88353121 |
| 86 | TDRD3_21172665_ChIP-Seq_MCF-7_Human | 0.87582985 |
| 87 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 0.87190273 |
| 88 | GATA3_26560356_Chip-Seq_TH2_Human | 0.85524982 |
| 89 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 0.85258807 |
| 90 | OCT4_20526341_ChIP-Seq_ESCs_Human | 0.84950141 |
| 91 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 0.84581936 |
| 92 | AR_20517297_ChIP-Seq_VCAP_Human | 0.83750034 |
| 93 | NANOG_16153702_ChIP-ChIP_HESCs_Human | 0.83082809 |
| 94 | TAF2_19829295_ChIP-Seq_ESCs_Human | 0.81666310 |
| 95 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 0.81329005 |
| 96 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 0.81214014 |
| 97 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 0.80041005 |
| 98 | P300_19829295_ChIP-Seq_ESCs_Human | 0.80023290 |
| 99 | YY1_22570637_ChIP-Seq_MALME-3M_Human | 0.79839521 |
| 100 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 0.79495195 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0002736_abnormal_nociception_after | 3.40120552 |
| 2 | MP0001968_abnormal_touch/_nociception | 3.18731467 |
| 3 | MP0002102_abnormal_ear_morphology | 3.15635507 |
| 4 | MP0003195_calcinosis | 3.02370201 |
| 5 | MP0005084_abnormal_gallbladder_morpholo | 2.80142832 |
| 6 | MP0005360_urolithiasis | 2.65320053 |
| 7 | MP0008875_abnormal_xenobiotic_pharmacok | 2.61067287 |
| 8 | MP0003718_maternal_effect | 2.53517307 |
| 9 | MP0006276_abnormal_autonomic_nervous | 2.52924627 |
| 10 | MP0008872_abnormal_physiological_respon | 2.47719223 |
| 11 | MP0003646_muscle_fatigue | 2.33597578 |
| 12 | MP0001984_abnormal_olfaction | 2.33539621 |
| 13 | MP0008058_abnormal_DNA_repair | 2.24372606 |
| 14 | MP0010094_abnormal_chromosome_stability | 2.19939377 |
| 15 | MP0006072_abnormal_retinal_apoptosis | 2.08784987 |
| 16 | MP0002166_altered_tumor_susceptibility | 2.04704430 |
| 17 | MP0003786_premature_aging | 1.92789593 |
| 18 | MP0002006_tumorigenesis | 1.87041479 |
| 19 | MP0002653_abnormal_ependyma_morphology | 1.80295934 |
| 20 | MP0005671_abnormal_response_to | 1.78267927 |
| 21 | MP0003880_abnormal_central_pattern | 1.76319287 |
| 22 | MP0000372_irregular_coat_pigmentation | 1.75322815 |
| 23 | MP0005551_abnormal_eye_electrophysiolog | 1.68271819 |
| 24 | MP0003011_delayed_dark_adaptation | 1.67865322 |
| 25 | MP0008260_abnormal_autophagy | 1.62331639 |
| 26 | MP0005645_abnormal_hypothalamus_physiol | 1.58587873 |
| 27 | MP0001970_abnormal_pain_threshold | 1.56366120 |
| 28 | MP0005646_abnormal_pituitary_gland | 1.55430976 |
| 29 | MP0001919_abnormal_reproductive_system | 1.51889398 |
| 30 | MP0009764_decreased_sensitivity_to | 1.50802513 |
| 31 | MP0005083_abnormal_biliary_tract | 1.49074592 |
| 32 | MP0005085_abnormal_gallbladder_physiolo | 1.47163726 |
| 33 | MP0008877_abnormal_DNA_methylation | 1.45021842 |
| 34 | MP0002938_white_spotting | 1.41249628 |
| 35 | MP0005253_abnormal_eye_physiology | 1.41054654 |
| 36 | MP0003122_maternal_imprinting | 1.39662529 |
| 37 | MP0003724_increased_susceptibility_to | 1.39229468 |
| 38 | MP0002733_abnormal_thermal_nociception | 1.37924978 |
| 39 | MP0002909_abnormal_adrenal_gland | 1.37222664 |
| 40 | MP0005377_hearing/vestibular/ear_phenot | 1.36223658 |
| 41 | MP0003878_abnormal_ear_physiology | 1.36223658 |
| 42 | MP0000465_gastrointestinal_hemorrhage | 1.35343821 |
| 43 | MP0002822_catalepsy | 1.34887898 |
| 44 | MP0002734_abnormal_mechanical_nocicepti | 1.31831280 |
| 45 | MP0001501_abnormal_sleep_pattern | 1.29137142 |
| 46 | MP0003567_abnormal_fetal_cardiomyocyte | 1.28158975 |
| 47 | MP0005423_abnormal_somatic_nervous | 1.25973976 |
| 48 | MP0006054_spinal_hemorrhage | 1.23422277 |
| 49 | MP0003137_abnormal_impulse_conducting | 1.23096369 |
| 50 | MP0002272_abnormal_nervous_system | 1.23030104 |
| 51 | MP0002139_abnormal_hepatobiliary_system | 1.20540935 |
| 52 | MP0002009_preneoplasia | 1.14393757 |
| 53 | MP0006292_abnormal_olfactory_placode | 1.14305754 |
| 54 | MP0000647_abnormal_sebaceous_gland | 1.13766413 |
| 55 | MP0000631_abnormal_neuroendocrine_gland | 1.11809089 |
| 56 | MP0002064_seizures | 1.08885379 |
| 57 | MP0004145_abnormal_muscle_electrophysio | 1.07001826 |
| 58 | MP0001502_abnormal_circadian_rhythm | 1.05351371 |
| 59 | MP0010234_abnormal_vibrissa_follicle | 1.04160068 |
| 60 | MP0001905_abnormal_dopamine_level | 1.03642241 |
| 61 | MP0008995_early_reproductive_senescence | 1.02861012 |
| 62 | MP0001764_abnormal_homeostasis | 1.02858030 |
| 63 | MP0006036_abnormal_mitochondrial_physio | 1.00430107 |
| 64 | MP0002751_abnormal_autonomic_nervous | 1.00138898 |
| 65 | MP0006035_abnormal_mitochondrial_morpho | 0.99639430 |
| 66 | MP0009745_abnormal_behavioral_response | 0.98975111 |
| 67 | MP0005389_reproductive_system_phenotype | 0.98101014 |
| 68 | MP0004270_analgesia | 0.96074260 |
| 69 | MP0009046_muscle_twitch | 0.90329224 |
| 70 | MP0002572_abnormal_emotion/affect_behav | 0.82502160 |
| 71 | MP0005410_abnormal_fertilization | 0.81916746 |
| 72 | MP0003252_abnormal_bile_duct | 0.81342474 |
| 73 | MP0001529_abnormal_vocalization | 0.81138246 |
| 74 | MP0003191_abnormal_cellular_cholesterol | 0.81015251 |
| 75 | MP0004742_abnormal_vestibular_system | 0.80652774 |
| 76 | MP0001800_abnormal_humoral_immune | 0.80257542 |
| 77 | MP0001986_abnormal_taste_sensitivity | 0.79418506 |
| 78 | MP0004019_abnormal_vitamin_homeostasis | 0.79181551 |
| 79 | MP0001835_abnormal_antigen_presentation | 0.78799266 |
| 80 | MP0002876_abnormal_thyroid_physiology | 0.78513839 |
| 81 | MP0003121_genomic_imprinting | 0.77908635 |
| 82 | MP0001727_abnormal_embryo_implantation | 0.75521815 |
| 83 | MP0000685_abnormal_immune_system | 0.74694818 |
| 84 | MP0002735_abnormal_chemical_nociception | 0.74123920 |
| 85 | MP0002557_abnormal_social/conspecific_i | 0.73864418 |
| 86 | MP0002282_abnormal_trachea_morphology | 0.71283804 |
| 87 | MP0004147_increased_porphyrin_level | 0.70603514 |
| 88 | MP0001929_abnormal_gametogenesis | 0.69376970 |
| 89 | MP0008775_abnormal_heart_ventricle | 0.68600403 |
| 90 | MP0005365_abnormal_bile_salt | 0.68105852 |
| 91 | MP0003186_abnormal_redox_activity | 0.67899292 |
| 92 | MP0004215_abnormal_myocardial_fiber | 0.67462967 |
| 93 | MP0003111_abnormal_nucleus_morphology | 0.66580930 |
| 94 | MP0005332_abnormal_amino_acid | 0.64856058 |
| 95 | MP0003787_abnormal_imprinting | 0.64601669 |
| 96 | MP0004142_abnormal_muscle_tone | 0.64288041 |
| 97 | MP0002928_abnormal_bile_duct | 0.62506742 |
| 98 | MP0004924_abnormal_behavior | 0.62181490 |
| 99 | MP0005386_behavior/neurological_phenoty | 0.62181490 |
| 100 | MP0005195_abnormal_posterior_eye | 0.61317840 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Generalized aminoaciduria (HP:0002909) | 4.86450067 |
| 2 | Lipid accumulation in hepatocytes (HP:0006561) | 4.51288779 |
| 3 | Increased hepatocellular lipid droplets (HP:0006565) | 4.43838143 |
| 4 | Mitochondrial inheritance (HP:0001427) | 3.85092477 |
| 5 | Increased CSF lactate (HP:0002490) | 3.82729365 |
| 6 | Hepatic necrosis (HP:0002605) | 3.78818259 |
| 7 | Renal Fanconi syndrome (HP:0001994) | 3.72009288 |
| 8 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 3.62665244 |
| 9 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 3.62665244 |
| 10 | Hepatocellular necrosis (HP:0001404) | 3.40401604 |
| 11 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 3.38792094 |
| 12 | Increased intramyocellular lipid droplets (HP:0012240) | 3.38589322 |
| 13 | Acute necrotizing encephalopathy (HP:0006965) | 3.32755267 |
| 14 | Abnormal mitochondria in muscle tissue (HP:0008316) | 3.16085890 |
| 15 | Increased muscle lipid content (HP:0009058) | 3.07350064 |
| 16 | Abnormality of urine glucose concentration (HP:0011016) | 3.07139222 |
| 17 | Glycosuria (HP:0003076) | 3.07139222 |
| 18 | Increased serum lactate (HP:0002151) | 3.06028050 |
| 19 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 2.99947955 |
| 20 | Exertional dyspnea (HP:0002875) | 2.92211806 |
| 21 | Elevated erythrocyte sedimentation rate (HP:0003565) | 2.91858207 |
| 22 | Congenital stationary night blindness (HP:0007642) | 2.78348581 |
| 23 | Leukodystrophy (HP:0002415) | 2.76735896 |
| 24 | Abnormality of the anterior horn cell (HP:0006802) | 2.75527649 |
| 25 | Degeneration of anterior horn cells (HP:0002398) | 2.75527649 |
| 26 | Progressive microcephaly (HP:0000253) | 2.75083242 |
| 27 | Severe combined immunodeficiency (HP:0004430) | 2.72850535 |
| 28 | Dysautonomia (HP:0002459) | 2.72447784 |
| 29 | Acute encephalopathy (HP:0006846) | 2.69720927 |
| 30 | Renal cortical cysts (HP:0000803) | 2.69158254 |
| 31 | Progressive macrocephaly (HP:0004481) | 2.69145822 |
| 32 | Abnormality of macular pigmentation (HP:0008002) | 2.66142564 |
| 33 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 2.56568771 |
| 34 | Abolished electroretinogram (ERG) (HP:0000550) | 2.55495092 |
| 35 | Nausea (HP:0002018) | 2.50848098 |
| 36 | Poor head control (HP:0002421) | 2.50783672 |
| 37 | Lactic acidosis (HP:0003128) | 2.49805024 |
| 38 | Methylmalonic acidemia (HP:0002912) | 2.37655602 |
| 39 | Attenuation of retinal blood vessels (HP:0007843) | 2.36178478 |
| 40 | Increased serum pyruvate (HP:0003542) | 2.35298493 |
| 41 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 2.34251145 |
| 42 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 2.33376670 |
| 43 | Abnormality of alanine metabolism (HP:0010916) | 2.33376670 |
| 44 | Hyperalaninemia (HP:0003348) | 2.33376670 |
| 45 | Amniotic constriction ring (HP:0009775) | 2.30287356 |
| 46 | Abnormality of placental membranes (HP:0011409) | 2.30287356 |
| 47 | Abnormality of the renal cortex (HP:0011035) | 2.29202443 |
| 48 | Hypoplastic pelvis (HP:0008839) | 2.26469682 |
| 49 | IgG deficiency (HP:0004315) | 2.25632111 |
| 50 | Oral leukoplakia (HP:0002745) | 2.24493420 |
| 51 | Respiratory difficulties (HP:0002880) | 2.17051292 |
| 52 | Constricted visual fields (HP:0001133) | 2.13774940 |
| 53 | Hypoglycemic coma (HP:0001325) | 2.13188452 |
| 54 | Cerebral edema (HP:0002181) | 2.12720872 |
| 55 | Parakeratosis (HP:0001036) | 2.11652974 |
| 56 | Methylmalonic aciduria (HP:0012120) | 2.11244611 |
| 57 | Respiratory failure (HP:0002878) | 2.10128217 |
| 58 | Exercise intolerance (HP:0003546) | 2.08992135 |
| 59 | Decreased central vision (HP:0007663) | 2.07495567 |
| 60 | Inability to walk (HP:0002540) | 2.07381127 |
| 61 | Pancreatic cysts (HP:0001737) | 2.05358772 |
| 62 | Glucose intolerance (HP:0000833) | 2.04563749 |
| 63 | Abnormality of glycolysis (HP:0004366) | 2.02511264 |
| 64 | Combined immunodeficiency (HP:0005387) | 2.02335432 |
| 65 | Spastic paraparesis (HP:0002313) | 2.00811380 |
| 66 | Adrenal hypoplasia (HP:0000835) | 2.00462064 |
| 67 | Poor suck (HP:0002033) | 1.99349948 |
| 68 | Intellectual disability, profound (HP:0002187) | 1.99167686 |
| 69 | Optic disc pallor (HP:0000543) | 1.99064835 |
| 70 | Abnormality of renal resorption (HP:0011038) | 1.98685234 |
| 71 | Abnormality of cochlea (HP:0000375) | 1.97764179 |
| 72 | Thyroiditis (HP:0100646) | 1.95539765 |
| 73 | Abnormality of serum amino acid levels (HP:0003112) | 1.93092270 |
| 74 | Abnormality of long-chain fatty-acid metabolism (HP:0010964) | 1.86400206 |
| 75 | Atrophy/Degeneration involving motor neurons (HP:0007373) | 1.84690800 |
| 76 | Colon cancer (HP:0003003) | 1.84258547 |
| 77 | Abnormality of midbrain morphology (HP:0002418) | 1.83314634 |
| 78 | Molar tooth sign on MRI (HP:0002419) | 1.83314634 |
| 79 | Abnormality of fatty-acid metabolism (HP:0004359) | 1.81607857 |
| 80 | Erythroderma (HP:0001019) | 1.81445050 |
| 81 | Dicarboxylic aciduria (HP:0003215) | 1.80954912 |
| 82 | Abnormality of dicarboxylic acid metabolism (HP:0010995) | 1.80954912 |
| 83 | Hyperphosphaturia (HP:0003109) | 1.80391350 |
| 84 | Lethargy (HP:0001254) | 1.78818558 |
| 85 | Progressive inability to walk (HP:0002505) | 1.76103297 |
| 86 | True hermaphroditism (HP:0010459) | 1.75554656 |
| 87 | Failure to thrive in infancy (HP:0001531) | 1.75323948 |
| 88 | CNS demyelination (HP:0007305) | 1.74163565 |
| 89 | Pachygyria (HP:0001302) | 1.72203054 |
| 90 | Myositis (HP:0100614) | 1.71739221 |
| 91 | X-linked dominant inheritance (HP:0001423) | 1.70150503 |
| 92 | Facial diplegia (HP:0001349) | 1.69941105 |
| 93 | Epiphyseal stippling (HP:0010655) | 1.69290480 |
| 94 | Limb dystonia (HP:0002451) | 1.69177553 |
| 95 | Large eyes (HP:0001090) | 1.68848594 |
| 96 | Muscular hypotonia of the trunk (HP:0008936) | 1.68436467 |
| 97 | Tinnitus (HP:0000360) | 1.66065514 |
| 98 | Hypoproteinemia (HP:0003075) | 1.65714796 |
| 99 | Limb-girdle muscle atrophy (HP:0003797) | 1.65437193 |
| 100 | Bony spicule pigmentary retinopathy (HP:0007737) | 1.65065317 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | ZAK | 6.66356969 |
| 2 | TLK1 | 4.14323183 |
| 3 | VRK2 | 4.09312196 |
| 4 | VRK1 | 3.47424333 |
| 5 | MAP2K7 | 2.24734639 |
| 6 | WNK3 | 2.23952943 |
| 7 | NUAK1 | 2.14439305 |
| 8 | MAP3K4 | 2.11870803 |
| 9 | CCNB1 | 1.89511935 |
| 10 | TRIM28 | 1.80732840 |
| 11 | BUB1 | 1.80375048 |
| 12 | CSNK1G3 | 1.56118294 |
| 13 | TAF1 | 1.52121894 |
| 14 | TXK | 1.49709373 |
| 15 | ADRBK2 | 1.49700931 |
| 16 | TESK2 | 1.47643688 |
| 17 | PDK2 | 1.46366014 |
| 18 | SMG1 | 1.40097788 |
| 19 | MST4 | 1.39349761 |
| 20 | GRK1 | 1.39259504 |
| 21 | PLK2 | 1.36667717 |
| 22 | CSNK1A1L | 1.36527534 |
| 23 | KDR | 1.34344047 |
| 24 | TAOK3 | 1.31620379 |
| 25 | WNK4 | 1.25248499 |
| 26 | EIF2AK3 | 1.25161812 |
| 27 | MAPK13 | 1.24652387 |
| 28 | TSSK6 | 1.24436925 |
| 29 | DAPK3 | 1.22911205 |
| 30 | ERBB3 | 1.22469091 |
| 31 | MAP4K2 | 1.19663231 |
| 32 | RPS6KA5 | 1.17528508 |
| 33 | BLK | 1.16752258 |
| 34 | STK39 | 1.14012251 |
| 35 | CSNK1G2 | 1.13222790 |
| 36 | CSNK1G1 | 1.12932318 |
| 37 | BCR | 1.11709139 |
| 38 | DAPK1 | 1.11681382 |
| 39 | CASK | 1.08595146 |
| 40 | PBK | 1.08561749 |
| 41 | AURKA | 1.06486080 |
| 42 | PLK3 | 1.05970940 |
| 43 | DYRK2 | 1.01549632 |
| 44 | BCKDK | 0.96529351 |
| 45 | STK16 | 0.94193809 |
| 46 | LIMK1 | 0.93077128 |
| 47 | UHMK1 | 0.88688070 |
| 48 | NME1 | 0.83457544 |
| 49 | GRK6 | 0.80958688 |
| 50 | CDK9 | 0.80668849 |
| 51 | MAP2K2 | 0.77338670 |
| 52 | EPHA4 | 0.75409135 |
| 53 | NEK1 | 0.74829192 |
| 54 | CHEK2 | 0.74714446 |
| 55 | FRK | 0.69864782 |
| 56 | ATR | 0.69435071 |
| 57 | MAPKAPK5 | 0.65924066 |
| 58 | INSRR | 0.65789759 |
| 59 | PIK3CG | 0.65715528 |
| 60 | MAP2K6 | 0.64233659 |
| 61 | CDK6 | 0.64082765 |
| 62 | MYLK | 0.63873392 |
| 63 | AURKB | 0.62777615 |
| 64 | BMPR1B | 0.61003553 |
| 65 | OXSR1 | 0.59655569 |
| 66 | PLK4 | 0.59403455 |
| 67 | MARK1 | 0.58615205 |
| 68 | TESK1 | 0.57405850 |
| 69 | MAP3K12 | 0.57390373 |
| 70 | GRK5 | 0.56123257 |
| 71 | SYK | 0.55121253 |
| 72 | DAPK2 | 0.50400304 |
| 73 | PKN1 | 0.49413813 |
| 74 | ITK | 0.48800288 |
| 75 | MAPKAPK3 | 0.48733463 |
| 76 | PIM1 | 0.48633653 |
| 77 | PAK3 | 0.48300964 |
| 78 | PRKCQ | 0.48290836 |
| 79 | PRKCG | 0.47323089 |
| 80 | CDK4 | 0.44121321 |
| 81 | EIF2AK2 | 0.44059573 |
| 82 | PRKAA1 | 0.43228008 |
| 83 | LYN | 0.42145533 |
| 84 | OBSCN | 0.41475729 |
| 85 | IKBKB | 0.41242617 |
| 86 | MAP3K14 | 0.40657769 |
| 87 | PAK6 | 0.38297437 |
| 88 | CDK18 | 0.38232317 |
| 89 | CSNK2A1 | 0.37704639 |
| 90 | CAMK2A | 0.33838837 |
| 91 | MAP4K1 | 0.33597651 |
| 92 | DYRK1B | 0.33465566 |
| 93 | CDK14 | 0.33449634 |
| 94 | PINK1 | 0.31912364 |
| 95 | MAPK15 | 0.31860521 |
| 96 | DYRK3 | 0.31359377 |
| 97 | CDK15 | 0.31005451 |
| 98 | CSNK2A2 | 0.28226899 |
| 99 | PRKCE | 0.28133843 |
| 100 | PRKCA | 0.27916424 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 4.40735065 |
| 2 | Proteasome_Homo sapiens_hsa03050 | 4.10661384 |
| 3 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 3.84162976 |
| 4 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 3.11605280 |
| 5 | Alcoholism_Homo sapiens_hsa05034 | 2.88601641 |
| 6 | Steroid biosynthesis_Homo sapiens_hsa00100 | 2.73128403 |
| 7 | Parkinsons disease_Homo sapiens_hsa05012 | 2.53998230 |
| 8 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 2.21844888 |
| 9 | DNA replication_Homo sapiens_hsa03030 | 2.07109145 |
| 10 | Non-homologous end-joining_Homo sapiens_hsa03450 | 2.05677820 |
| 11 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 1.81443616 |
| 12 | RNA polymerase_Homo sapiens_hsa03020 | 1.79547855 |
| 13 | Protein export_Homo sapiens_hsa03060 | 1.75295559 |
| 14 | Basal transcription factors_Homo sapiens_hsa03022 | 1.67457263 |
| 15 | Sulfur metabolism_Homo sapiens_hsa00920 | 1.66273510 |
| 16 | Mismatch repair_Homo sapiens_hsa03430 | 1.66223192 |
| 17 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.63988431 |
| 18 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.62118000 |
| 19 | Huntingtons disease_Homo sapiens_hsa05016 | 1.58028072 |
| 20 | Alzheimers disease_Homo sapiens_hsa05010 | 1.51783141 |
| 21 | Homologous recombination_Homo sapiens_hsa03440 | 1.49549312 |
| 22 | Tryptophan metabolism_Homo sapiens_hsa00380 | 1.48876202 |
| 23 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.39657080 |
| 24 | Phototransduction_Homo sapiens_hsa04744 | 1.30698481 |
| 25 | Fatty acid elongation_Homo sapiens_hsa00062 | 1.30150645 |
| 26 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.28910804 |
| 27 | Sulfur relay system_Homo sapiens_hsa04122 | 1.16910040 |
| 28 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 1.15859674 |
| 29 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 1.14916168 |
| 30 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 1.11002049 |
| 31 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 1.08538225 |
| 32 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.05785302 |
| 33 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.03134259 |
| 34 | Asthma_Homo sapiens_hsa05310 | 1.03099159 |
| 35 | Glutathione metabolism_Homo sapiens_hsa00480 | 1.01583347 |
| 36 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.01511254 |
| 37 | Viral carcinogenesis_Homo sapiens_hsa05203 | 1.00270896 |
| 38 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.00023719 |
| 39 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.98126366 |
| 40 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.97629533 |
| 41 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.96110344 |
| 42 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.96021375 |
| 43 | Spliceosome_Homo sapiens_hsa03040 | 0.94737603 |
| 44 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.92629814 |
| 45 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 0.91776778 |
| 46 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.91600051 |
| 47 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.91320908 |
| 48 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.90605165 |
| 49 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.88867516 |
| 50 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.88700988 |
| 51 | RNA transport_Homo sapiens_hsa03013 | 0.88542346 |
| 52 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 0.86741564 |
| 53 | Base excision repair_Homo sapiens_hsa03410 | 0.84566634 |
| 54 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.82420248 |
| 55 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.82000493 |
| 56 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.79910617 |
| 57 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.79434423 |
| 58 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.78069285 |
| 59 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.76996102 |
| 60 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.76883126 |
| 61 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.75505678 |
| 62 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.74163926 |
| 63 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.73829355 |
| 64 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.70392597 |
| 65 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.69232292 |
| 66 | Purine metabolism_Homo sapiens_hsa00230 | 0.68134152 |
| 67 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.67478747 |
| 68 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.67329613 |
| 69 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.67274900 |
| 70 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 0.64597434 |
| 71 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.64242613 |
| 72 | Peroxisome_Homo sapiens_hsa04146 | 0.64194958 |
| 73 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.63926581 |
| 74 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.63426503 |
| 75 | Metabolic pathways_Homo sapiens_hsa01100 | 0.63318101 |
| 76 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.61038828 |
| 77 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.60750546 |
| 78 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.60578730 |
| 79 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.60454512 |
| 80 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.59602048 |
| 81 | Olfactory transduction_Homo sapiens_hsa04740 | 0.57752456 |
| 82 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.55123829 |
| 83 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.51851248 |
| 84 | RNA degradation_Homo sapiens_hsa03018 | 0.51704613 |
| 85 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.48771133 |
| 86 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.48256792 |
| 87 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.48118841 |
| 88 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.45474079 |
| 89 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.44521643 |
| 90 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 0.42295666 |
| 91 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.41532879 |
| 92 | Carbon metabolism_Homo sapiens_hsa01200 | 0.37892711 |
| 93 | Allograft rejection_Homo sapiens_hsa05330 | 0.36950373 |
| 94 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 0.36686997 |
| 95 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.33851941 |
| 96 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.33291137 |
| 97 | Taste transduction_Homo sapiens_hsa04742 | 0.30776110 |
| 98 | Ribosome_Homo sapiens_hsa03010 | 0.30763508 |
| 99 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.29253566 |
| 100 | Histidine metabolism_Homo sapiens_hsa00340 | 0.28482090 |

