

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 6.99667179 |
| 2 | DNA deamination (GO:0045006) | 6.20115339 |
| 3 | cytidine deamination (GO:0009972) | 6.11390553 |
| 4 | cytidine metabolic process (GO:0046087) | 6.11390553 |
| 5 | cytidine catabolic process (GO:0006216) | 6.11390553 |
| 6 | RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503) | 5.16882350 |
| 7 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 5.14703492 |
| 8 | positive regulation of isotype switching (GO:0045830) | 4.94655619 |
| 9 | positive regulation of natural killer cell differentiation (GO:0032825) | 4.75928828 |
| 10 | regulation of B cell receptor signaling pathway (GO:0050855) | 4.74794229 |
| 11 | pyrimidine deoxyribonucleotide catabolic process (GO:0009223) | 4.66449759 |
| 12 | positive regulation of DNA recombination (GO:0045911) | 4.49216614 |
| 13 | regulation of activation of Janus kinase activity (GO:0010533) | 4.25743870 |
| 14 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 4.21399382 |
| 15 | positive regulation of histone H3-K4 methylation (GO:0051571) | 4.20596399 |
| 16 | water-soluble vitamin biosynthetic process (GO:0042364) | 4.19086867 |
| 17 | Arp2/3 complex-mediated actin nucleation (GO:0034314) | 4.14481263 |
| 18 | protein complex biogenesis (GO:0070271) | 4.07190431 |
| 19 | actin nucleation (GO:0045010) | 3.99373203 |
| 20 | maturation of 5.8S rRNA (GO:0000460) | 3.91774489 |
| 21 | negative regulation of mast cell activation (GO:0033004) | 3.89210143 |
| 22 | positive regulation of immunoglobulin mediated immune response (GO:0002891) | 3.86306705 |
| 23 | positive regulation of B cell mediated immunity (GO:0002714) | 3.86306705 |
| 24 | iron-sulfur cluster assembly (GO:0016226) | 3.85346465 |
| 25 | metallo-sulfur cluster assembly (GO:0031163) | 3.85346465 |
| 26 | negative regulation of phagocytosis (GO:0050765) | 3.82638457 |
| 27 | positive T cell selection (GO:0043368) | 3.75932972 |
| 28 | positive regulation of phosphoprotein phosphatase activity (GO:0032516) | 3.75192186 |
| 29 | pyrimidine nucleotide catabolic process (GO:0006244) | 3.75124223 |
| 30 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.68385207 |
| 31 | replicative senescence (GO:0090399) | 3.67002031 |
| 32 | isoprenoid biosynthetic process (GO:0008299) | 3.65421036 |
| 33 | hepatocyte apoptotic process (GO:0097284) | 3.61991974 |
| 34 | ubiquinone biosynthetic process (GO:0006744) | 3.60076993 |
| 35 | proteasome assembly (GO:0043248) | 3.57198816 |
| 36 | ubiquinone metabolic process (GO:0006743) | 3.52828861 |
| 37 | quinone biosynthetic process (GO:1901663) | 3.50385545 |
| 38 | terpenoid biosynthetic process (GO:0016114) | 3.46716654 |
| 39 | positive regulation of natural killer cell mediated cytotoxicity (GO:0045954) | 3.43699360 |
| 40 | response to interferon-beta (GO:0035456) | 3.38378631 |
| 41 | regulation of natural killer cell differentiation (GO:0032823) | 3.35562909 |
| 42 | cellular response to zinc ion (GO:0071294) | 3.34878989 |
| 43 | platelet dense granule organization (GO:0060155) | 3.29631668 |
| 44 | regulation of mitochondrial translation (GO:0070129) | 3.27945549 |
| 45 | positive regulation of natural killer cell mediated immunity (GO:0002717) | 3.27556918 |
| 46 | positive regulation of immunoglobulin production (GO:0002639) | 3.27216030 |
| 47 | negative regulation of viral genome replication (GO:0045071) | 3.24470378 |
| 48 | antigen processing and presentation via MHC class Ib (GO:0002475) | 3.23061723 |
| 49 | pyrimidine nucleoside catabolic process (GO:0046135) | 3.18505999 |
| 50 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.11661842 |
| 51 | negative regulation of antigen receptor-mediated signaling pathway (GO:0050858) | 3.11397385 |
| 52 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.10987487 |
| 53 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.10987487 |
| 54 | mannosylation (GO:0097502) | 3.07855086 |
| 55 | protein heterotetramerization (GO:0051290) | 3.07670322 |
| 56 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 3.07328393 |
| 57 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.07265087 |
| 58 | DNA demethylation (GO:0080111) | 3.05942494 |
| 59 | regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis (GO:0003339 | 3.05567493 |
| 60 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 3.04030053 |
| 61 | NADH dehydrogenase complex assembly (GO:0010257) | 3.04030053 |
| 62 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 3.04030053 |
| 63 | cytochrome complex assembly (GO:0017004) | 3.03795659 |
| 64 | regulation of cellular amino acid metabolic process (GO:0006521) | 3.02430326 |
| 65 | pyrimidine deoxyribonucleotide metabolic process (GO:0009219) | 3.01549693 |
| 66 | regulation of T cell chemotaxis (GO:0010819) | 3.00551615 |
| 67 | positive regulation of T cell chemotaxis (GO:0010820) | 3.00551615 |
| 68 | positive regulation of leukocyte mediated cytotoxicity (GO:0001912) | 3.00508797 |
| 69 | cellular response to interleukin-15 (GO:0071350) | 3.00260225 |
| 70 | protein deneddylation (GO:0000338) | 2.90166444 |
| 71 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 2.88262072 |
| 72 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 2.87125158 |
| 73 | rRNA catabolic process (GO:0016075) | 2.84269076 |
| 74 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 2.83995792 |
| 75 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 2.83995792 |
| 76 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 2.83995792 |
| 77 | transcription elongation from RNA polymerase I promoter (GO:0006362) | 2.83040031 |
| 78 | regulation of T cell receptor signaling pathway (GO:0050856) | 2.81302460 |
| 79 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 2.78766531 |
| 80 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 2.78725108 |
| 81 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 2.78725108 |
| 82 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 2.78111098 |
| 83 | ATP synthesis coupled proton transport (GO:0015986) | 2.78111098 |
| 84 | negative regulation of macrophage derived foam cell differentiation (GO:0010745) | 2.76322677 |
| 85 | regulation of antigen receptor-mediated signaling pathway (GO:0050854) | 2.75055898 |
| 86 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 2.72709253 |
| 87 | negative regulation of ligase activity (GO:0051352) | 2.72709253 |
| 88 | positive regulation of transcription initiation from RNA polymerase II promoter (GO:0060261) | 2.72080594 |
| 89 | negative regulation of hematopoietic progenitor cell differentiation (GO:1901533) | 2.70960826 |
| 90 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 2.70915607 |
| 91 | respiratory electron transport chain (GO:0022904) | 2.70519797 |
| 92 | regulation of isotype switching (GO:0045191) | 2.70484755 |
| 93 | positive regulation of cell killing (GO:0031343) | 2.68018894 |
| 94 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO: | 2.67521491 |
| 95 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 2.66835344 |
| 96 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 2.66835344 |
| 97 | adenosine metabolic process (GO:0046085) | 2.66721513 |
| 98 | pseudouridine synthesis (GO:0001522) | 2.66527475 |
| 99 | T cell selection (GO:0045058) | 2.64174158 |
| 100 | electron transport chain (GO:0022900) | 2.63937371 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 4.19462372 |
| 2 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 4.03943949 |
| 3 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 3.85163614 |
| 4 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 3.77610229 |
| 5 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 3.55425861 |
| 6 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 3.44001235 |
| 7 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 3.39877692 |
| 8 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.11477030 |
| 9 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 3.10331834 |
| 10 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 3.07910185 |
| 11 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 3.03302032 |
| 12 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.51616493 |
| 13 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.48922876 |
| 14 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.44818847 |
| 15 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 2.34127525 |
| 16 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.12987202 |
| 17 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 2.10220764 |
| 18 | VDR_22108803_ChIP-Seq_LS180_Human | 2.06429255 |
| 19 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 2.04902620 |
| 20 | GATA3_26560356_Chip-Seq_TH2_Human | 2.02696288 |
| 21 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 2.00828004 |
| 22 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.00436409 |
| 23 | MYB_26560356_Chip-Seq_TH2_Human | 1.94136731 |
| 24 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 1.86619377 |
| 25 | GATA1_22025678_ChIP-Seq_K562_Human | 1.85744739 |
| 26 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 1.82303850 |
| 27 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.81925037 |
| 28 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.75494691 |
| 29 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.72384928 |
| 30 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 1.72356087 |
| 31 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 1.68087797 |
| 32 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.67503604 |
| 33 | RUNX_20019798_ChIP-Seq_JUKART_Human | 1.64239231 |
| 34 | PPARD_23208498_ChIP-Seq_MDA-MB-231_Human | 1.60645985 |
| 35 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.46753200 |
| 36 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.46355666 |
| 37 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 1.45129766 |
| 38 | AR_20517297_ChIP-Seq_VCAP_Human | 1.45033660 |
| 39 | GATA3_27048872_Chip-Seq_THYMUS_Human | 1.42344292 |
| 40 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.38159249 |
| 41 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 1.35830941 |
| 42 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.35418894 |
| 43 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.32874412 |
| 44 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 1.31316567 |
| 45 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.30806472 |
| 46 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.30806472 |
| 47 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.29693783 |
| 48 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.26757190 |
| 49 | NCOR_22424771_ChIP-Seq_293T_Human | 1.26123259 |
| 50 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.24304436 |
| 51 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.20941218 |
| 52 | MYB_26560356_Chip-Seq_TH1_Human | 1.20891809 |
| 53 | EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 1.16993530 |
| 54 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.16937568 |
| 55 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.15428007 |
| 56 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 1.14110531 |
| 57 | EWS_26573619_Chip-Seq_HEK293_Human | 1.13643082 |
| 58 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 1.13635939 |
| 59 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.13551874 |
| 60 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.11669721 |
| 61 | GATA1_26923725_Chip-Seq_HPCs_Mouse | 1.10508919 |
| 62 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 1.10231306 |
| 63 | STAT1_20625510_ChIP-Seq_HELA_Human | 1.08933846 |
| 64 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.08046726 |
| 65 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.08046726 |
| 66 | NANOG_20526341_ChIP-Seq_ESCs_Human | 1.04556333 |
| 67 | P63_20808887_ChIP-Seq_KERATINOCYTES_Human | 1.04476657 |
| 68 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.02754223 |
| 69 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 1.02364900 |
| 70 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 1.02049603 |
| 71 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.01709819 |
| 72 | HOXB7_26014856_ChIP-Seq_BT474_Human | 1.01218516 |
| 73 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 1.00528878 |
| 74 | BCAT_22108803_ChIP-Seq_LS180_Human | 0.99448276 |
| 75 | CTCF_20526341_ChIP-Seq_ESCs_Human | 0.99268160 |
| 76 | HTT_18923047_ChIP-ChIP_STHdh_Human | 0.98963476 |
| 77 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 0.97970472 |
| 78 | FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.97325628 |
| 79 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 0.96683365 |
| 80 | EBNA1_20929547_Chip-Seq_RAJI-cells_Human | 0.92970849 |
| 81 | SPI1_23547873_ChIP-Seq_NB4_Human | 0.91846260 |
| 82 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.91302201 |
| 83 | FUS_26573619_Chip-Seq_HEK293_Human | 0.90038206 |
| 84 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 0.89634590 |
| 85 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 0.89105079 |
| 86 | BCL6_27268052_Chip-Seq_Bcells_Human | 0.89086896 |
| 87 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 0.88795353 |
| 88 | TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.88272682 |
| 89 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 0.88042908 |
| 90 | ERA_21632823_ChIP-Seq_H3396_Human | 0.87951116 |
| 91 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 0.87388525 |
| 92 | CIITA_25753668_ChIP-Seq_RAJI_Human | 0.87353507 |
| 93 | RUNX1_17652178_ChIP-ChIP_JURKAT_Human | 0.86352739 |
| 94 | CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse | 0.86121343 |
| 95 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 0.85695024 |
| 96 | TP53_22573176_ChIP-Seq_HFKS_Human | 0.82640426 |
| 97 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 0.82301018 |
| 98 | MAF_26560356_Chip-Seq_TH2_Human | 0.81982066 |
| 99 | EZH2_22144423_ChIP-Seq_EOC_Human | 0.81863844 |
| 100 | RUNX1_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.81577162 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0002138_abnormal_hepatobiliary_system | 5.75707386 |
| 2 | MP0005671_abnormal_response_to | 5.03861502 |
| 3 | MP0008057_abnormal_DNA_replication | 4.54645975 |
| 4 | MP0000685_abnormal_immune_system | 3.54011919 |
| 5 | MP0002166_altered_tumor_susceptibility | 3.14115830 |
| 6 | MP0005387_immune_system_phenotype | 3.13493549 |
| 7 | MP0001790_abnormal_immune_system | 3.13493549 |
| 8 | MP0001835_abnormal_antigen_presentation | 3.05313859 |
| 9 | MP0009785_altered_susceptibility_to | 3.02364693 |
| 10 | MP0003646_muscle_fatigue | 2.57566091 |
| 11 | MP0003763_abnormal_thymus_physiology | 2.56174409 |
| 12 | MP0002006_tumorigenesis | 2.50700860 |
| 13 | MP0002653_abnormal_ependyma_morphology | 2.34414507 |
| 14 | MP0001800_abnormal_humoral_immune | 2.06264255 |
| 15 | MP0004147_increased_porphyrin_level | 1.95389980 |
| 16 | MP0002876_abnormal_thyroid_physiology | 1.87629124 |
| 17 | MP0003195_calcinosis | 1.81415991 |
| 18 | MP0005408_hypopigmentation | 1.81313072 |
| 19 | MP0003172_abnormal_lysosome_physiology | 1.77201333 |
| 20 | MP0002148_abnormal_hypersensitivity_rea | 1.76253726 |
| 21 | MP0003880_abnormal_central_pattern | 1.72692470 |
| 22 | MP0005025_abnormal_response_to | 1.68029188 |
| 23 | MP0005075_abnormal_melanosome_morpholog | 1.65048827 |
| 24 | MP0004145_abnormal_muscle_electrophysio | 1.62874157 |
| 25 | MP0001968_abnormal_touch/_nociception | 1.60984947 |
| 26 | MP0002723_abnormal_immune_serum | 1.57309623 |
| 27 | MP0003436_decreased_susceptibility_to | 1.56168461 |
| 28 | MP0000372_irregular_coat_pigmentation | 1.55348308 |
| 29 | MP0005377_hearing/vestibular/ear_phenot | 1.53896942 |
| 30 | MP0003878_abnormal_ear_physiology | 1.53896942 |
| 31 | MP0009840_abnormal_foam_cell | 1.52979672 |
| 32 | MP0005645_abnormal_hypothalamus_physiol | 1.50975022 |
| 33 | MP0001873_stomach_inflammation | 1.50537966 |
| 34 | MP0002277_abnormal_respiratory_mucosa | 1.45890896 |
| 35 | MP0009764_decreased_sensitivity_to | 1.43061018 |
| 36 | MP0005000_abnormal_immune_tolerance | 1.42497397 |
| 37 | MP0001533_abnormal_skeleton_physiology | 1.37964876 |
| 38 | MP0002420_abnormal_adaptive_immunity | 1.37017544 |
| 39 | MP0002452_abnormal_antigen_presenting | 1.35748786 |
| 40 | MP0001819_abnormal_immune_cell | 1.35711583 |
| 41 | MP0004885_abnormal_endolymph | 1.33203649 |
| 42 | MP0000569_abnormal_digit_pigmentation | 1.32035071 |
| 43 | MP0002837_dystrophic_cardiac_calcinosis | 1.31857117 |
| 44 | MP0002095_abnormal_skin_pigmentation | 1.31562739 |
| 45 | MP0001905_abnormal_dopamine_level | 1.28597803 |
| 46 | MP0003638_abnormal_response/metabolism_ | 1.28311463 |
| 47 | MP0001243_abnormal_dermal_layer | 1.17839408 |
| 48 | MP0001853_heart_inflammation | 1.13248732 |
| 49 | MP0008872_abnormal_physiological_respon | 1.13005803 |
| 50 | MP0005319_abnormal_enzyme/_coenzyme | 1.11693531 |
| 51 | MP0005503_abnormal_tendon_morphology | 1.09323710 |
| 52 | MP0005084_abnormal_gallbladder_morpholo | 1.08401549 |
| 53 | MP0010155_abnormal_intestine_physiology | 1.07405227 |
| 54 | MP0002102_abnormal_ear_morphology | 1.06947062 |
| 55 | MP0001845_abnormal_inflammatory_respons | 1.05913370 |
| 56 | MP0009278_abnormal_bone_marrow | 1.05450022 |
| 57 | MP0002933_joint_inflammation | 1.05241505 |
| 58 | MP0000716_abnormal_immune_system | 1.05219822 |
| 59 | MP0002735_abnormal_chemical_nociception | 1.02731143 |
| 60 | MP0002736_abnormal_nociception_after | 0.99745003 |
| 61 | MP0002398_abnormal_bone_marrow | 0.99039341 |
| 62 | MP0000490_abnormal_crypts_of | 0.95644344 |
| 63 | MP0000858_altered_metastatic_potential | 0.92601295 |
| 64 | MP0004381_abnormal_hair_follicle | 0.91285395 |
| 65 | MP0003866_abnormal_defecation | 0.88704160 |
| 66 | MP0009643_abnormal_urine_homeostasis | 0.87216401 |
| 67 | MP0003724_increased_susceptibility_to | 0.85156191 |
| 68 | MP0004019_abnormal_vitamin_homeostasis | 0.83619428 |
| 69 | MP0002419_abnormal_innate_immunity | 0.83375012 |
| 70 | MP0002405_respiratory_system_inflammati | 0.81392530 |
| 71 | MP0001485_abnormal_pinna_reflex | 0.81343563 |
| 72 | MP0008058_abnormal_DNA_repair | 0.81078003 |
| 73 | MP0000703_abnormal_thymus_morphology | 0.80835545 |
| 74 | MP0005464_abnormal_platelet_physiology | 0.79819119 |
| 75 | MP0002429_abnormal_blood_cell | 0.78094745 |
| 76 | MP0008469_abnormal_protein_level | 0.77727375 |
| 77 | MP0004947_skin_inflammation | 0.76829995 |
| 78 | MP0008775_abnormal_heart_ventricle | 0.76233115 |
| 79 | MP0000613_abnormal_salivary_gland | 0.75315962 |
| 80 | MP0008875_abnormal_xenobiotic_pharmacok | 0.74979307 |
| 81 | MP0004957_abnormal_blastocyst_morpholog | 0.74391787 |
| 82 | MP0001958_emphysema | 0.73645717 |
| 83 | MP0002722_abnormal_immune_system | 0.73420257 |
| 84 | MP0005390_skeleton_phenotype | 0.71129853 |
| 85 | MP0003448_altered_tumor_morphology | 0.70956500 |
| 86 | MP0002938_white_spotting | 0.68960722 |
| 87 | MP0003806_abnormal_nucleotide_metabolis | 0.68799636 |
| 88 | MP0006036_abnormal_mitochondrial_physio | 0.68259502 |
| 89 | MP0001663_abnormal_digestive_system | 0.67129888 |
| 90 | MP0001119_abnormal_female_reproductive | 0.66960508 |
| 91 | MP0000689_abnormal_spleen_morphology | 0.65579088 |
| 92 | MP0002693_abnormal_pancreas_physiology | 0.65180813 |
| 93 | MP0004215_abnormal_myocardial_fiber | 0.64562089 |
| 94 | MP0005584_abnormal_enzyme/coenzyme_acti | 0.63581515 |
| 95 | MP0000604_amyloidosis | 0.63251353 |
| 96 | MP0006035_abnormal_mitochondrial_morpho | 0.63210011 |
| 97 | MP0005266_abnormal_metabolism | 0.62674437 |
| 98 | MP0005410_abnormal_fertilization | 0.62487341 |
| 99 | MP0003137_abnormal_impulse_conducting | 0.61221916 |
| 100 | MP0002733_abnormal_thermal_nociception | 0.60748057 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Decreased circulating renin level (HP:0003351) | 4.33772763 |
| 2 | Stomatitis (HP:0010280) | 4.06454302 |
| 3 | Increased IgM level (HP:0003496) | 4.03727378 |
| 4 | Hypoproteinemia (HP:0003075) | 3.86270652 |
| 5 | IgG deficiency (HP:0004315) | 3.85636352 |
| 6 | Abnormality of aromatic amino acid family metabolism (HP:0004338) | 3.82620066 |
| 7 | Hepatocellular necrosis (HP:0001404) | 3.71734359 |
| 8 | Depressed nasal tip (HP:0000437) | 3.67512004 |
| 9 | Increased CSF lactate (HP:0002490) | 3.63534793 |
| 10 | Hepatic necrosis (HP:0002605) | 3.46056632 |
| 11 | Mitochondrial inheritance (HP:0001427) | 3.45344002 |
| 12 | Severe combined immunodeficiency (HP:0004430) | 3.42511722 |
| 13 | Aplastic anemia (HP:0001915) | 3.23420129 |
| 14 | Elevated erythrocyte sedimentation rate (HP:0003565) | 3.17316648 |
| 15 | Tongue fasciculations (HP:0001308) | 3.06551797 |
| 16 | Cutaneous melanoma (HP:0012056) | 3.05283516 |
| 17 | T lymphocytopenia (HP:0005403) | 3.04607295 |
| 18 | Prostate neoplasm (HP:0100787) | 2.98152312 |
| 19 | Increased hepatocellular lipid droplets (HP:0006565) | 2.97435372 |
| 20 | Acute necrotizing encephalopathy (HP:0006965) | 2.93993439 |
| 21 | Increased serum lactate (HP:0002151) | 2.92681807 |
| 22 | Abnormality of T cell number (HP:0011839) | 2.90743757 |
| 23 | Pustule (HP:0200039) | 2.89407832 |
| 24 | Aortic regurgitation (HP:0001659) | 2.87988723 |
| 25 | Renal Fanconi syndrome (HP:0001994) | 2.86501588 |
| 26 | Cellular immunodeficiency (HP:0005374) | 2.81007855 |
| 27 | Lipid accumulation in hepatocytes (HP:0006561) | 2.77196609 |
| 28 | Recurrent cutaneous fungal infections (HP:0011370) | 2.72491629 |
| 29 | Chronic mucocutaneous candidiasis (HP:0002728) | 2.72491629 |
| 30 | Abnormality of midbrain morphology (HP:0002418) | 2.72099509 |
| 31 | Molar tooth sign on MRI (HP:0002419) | 2.72099509 |
| 32 | Hyperactive renin-angiotensin system (HP:0000841) | 2.70993347 |
| 33 | Nephronophthisis (HP:0000090) | 2.63219533 |
| 34 | Muscle fibrillation (HP:0010546) | 2.60166788 |
| 35 | Combined immunodeficiency (HP:0005387) | 2.59998264 |
| 36 | Type II lissencephaly (HP:0007260) | 2.58273652 |
| 37 | Pancytopenia (HP:0001876) | 2.55811099 |
| 38 | Abnormality of renin-angiotensin system (HP:0000847) | 2.55728727 |
| 39 | Conical tooth (HP:0000698) | 2.50167035 |
| 40 | Thyroiditis (HP:0100646) | 2.50118454 |
| 41 | Constricted visual fields (HP:0001133) | 2.47049333 |
| 42 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 2.46580943 |
| 43 | Abnormality of alanine metabolism (HP:0010916) | 2.46580943 |
| 44 | Hyperalaninemia (HP:0003348) | 2.46580943 |
| 45 | Mesangial abnormality (HP:0001966) | 2.46568669 |
| 46 | Progressive macrocephaly (HP:0004481) | 2.45853036 |
| 47 | Abnormal mitochondria in muscle tissue (HP:0008316) | 2.45574113 |
| 48 | Abnormality of the prostate (HP:0008775) | 2.45327210 |
| 49 | Abolished electroretinogram (ERG) (HP:0000550) | 2.37119994 |
| 50 | Metaphyseal dysplasia (HP:0100255) | 2.33468988 |
| 51 | Amelogenesis imperfecta (HP:0000705) | 2.33395913 |
| 52 | Acute encephalopathy (HP:0006846) | 2.32282382 |
| 53 | Lip pit (HP:0100267) | 2.29021445 |
| 54 | Pancreatic cysts (HP:0001737) | 2.27635459 |
| 55 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 2.26199356 |
| 56 | Abnormal protein N-linked glycosylation (HP:0012347) | 2.26199356 |
| 57 | Abnormal protein glycosylation (HP:0012346) | 2.26199356 |
| 58 | Abnormal glycosylation (HP:0012345) | 2.26199356 |
| 59 | Abnormality of renal resorption (HP:0011038) | 2.23107717 |
| 60 | Abnormality of the vocal cords (HP:0008777) | 2.20954572 |
| 61 | Abnormality of T cells (HP:0002843) | 2.20084379 |
| 62 | Hypergammaglobulinemia (HP:0010702) | 2.20042673 |
| 63 | Abnormality of eosinophils (HP:0001879) | 2.19470597 |
| 64 | J-shaped sella turcica (HP:0002680) | 2.19046423 |
| 65 | Tubular atrophy (HP:0000092) | 2.18235615 |
| 66 | Methylmalonic aciduria (HP:0012120) | 2.17067563 |
| 67 | Exertional dyspnea (HP:0002875) | 2.13959103 |
| 68 | Hyperaldosteronism (HP:0000859) | 2.12983994 |
| 69 | Hypoalbuminemia (HP:0003073) | 2.12439142 |
| 70 | Abnormal albumin level (HP:0012116) | 2.12439142 |
| 71 | Nausea (HP:0002018) | 2.11724938 |
| 72 | Chronic diarrhea (HP:0002028) | 2.10882152 |
| 73 | Neonatal respiratory distress (HP:0002643) | 2.10596920 |
| 74 | Hypokalemic alkalosis (HP:0001949) | 2.05653696 |
| 75 | Diaphragmatic weakness (HP:0009113) | 2.00467305 |
| 76 | Ileus (HP:0002595) | 1.99922476 |
| 77 | Methylmalonic acidemia (HP:0002912) | 1.99301049 |
| 78 | Respiratory failure (HP:0002878) | 1.96923628 |
| 79 | Increased intramyocellular lipid droplets (HP:0012240) | 1.96092373 |
| 80 | Abnormality of the neuromuscular junction (HP:0003398) | 1.95926861 |
| 81 | Fatigable weakness (HP:0003473) | 1.95926861 |
| 82 | Recurrent fungal infections (HP:0002841) | 1.95715579 |
| 83 | Optic disc pallor (HP:0000543) | 1.93736703 |
| 84 | Parakeratosis (HP:0001036) | 1.93362731 |
| 85 | Eosinophilia (HP:0001880) | 1.93293371 |
| 86 | Chronic bronchitis (HP:0004469) | 1.92238942 |
| 87 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 1.90775730 |
| 88 | Aplasia/Hypoplasia of the fovea (HP:0008060) | 1.88093028 |
| 89 | Hypoplasia of the fovea (HP:0007750) | 1.88093028 |
| 90 | Retinal dysplasia (HP:0007973) | 1.86398465 |
| 91 | Paralysis (HP:0003470) | 1.85661546 |
| 92 | Bronchitis (HP:0012387) | 1.85390614 |
| 93 | Multiple enchondromatosis (HP:0005701) | 1.81193566 |
| 94 | Abnormality of dental color (HP:0011073) | 1.80863131 |
| 95 | Recurrent bronchitis (HP:0002837) | 1.80682389 |
| 96 | Aplasia/Hypoplasia involving the musculature (HP:0001460) | 1.80164720 |
| 97 | Abnormality of the renal medulla (HP:0100957) | 1.79758654 |
| 98 | 3-Methylglutaconic aciduria (HP:0003535) | 1.79181875 |
| 99 | Abnormality of dicarboxylic acid metabolism (HP:0010995) | 1.78340018 |
| 100 | Dicarboxylic aciduria (HP:0003215) | 1.78340018 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MUSK | 5.59508711 |
| 2 | VRK2 | 4.81633749 |
| 3 | CDK8 | 3.88758357 |
| 4 | BMPR1B | 3.76826022 |
| 5 | ZAK | 3.48238008 |
| 6 | TLK1 | 3.29291570 |
| 7 | TXK | 3.20825182 |
| 8 | TESK1 | 2.95298869 |
| 9 | KDR | 2.77355225 |
| 10 | MAP4K2 | 2.67310079 |
| 11 | VRK1 | 2.56146228 |
| 12 | TGFBR1 | 2.41730624 |
| 13 | TAF1 | 2.24449037 |
| 14 | TSSK6 | 2.20424013 |
| 15 | MST4 | 1.84881004 |
| 16 | NUAK1 | 1.66678679 |
| 17 | EIF2AK1 | 1.63573650 |
| 18 | ADRBK2 | 1.59349772 |
| 19 | FRK | 1.51550160 |
| 20 | GRK1 | 1.48431790 |
| 21 | STK38 | 1.40976955 |
| 22 | CDK9 | 1.31697689 |
| 23 | MAP3K14 | 1.24536242 |
| 24 | IKBKE | 1.21696315 |
| 25 | IKBKB | 1.18113565 |
| 26 | MKNK2 | 1.17838526 |
| 27 | EIF2AK2 | 1.17828697 |
| 28 | WNK4 | 1.16141099 |
| 29 | STK39 | 1.15666842 |
| 30 | BUB1 | 1.15223251 |
| 31 | RPS6KA4 | 1.11303618 |
| 32 | KIT | 1.10566726 |
| 33 | TESK2 | 1.10025220 |
| 34 | MAP3K12 | 1.03986484 |
| 35 | MYLK | 1.02769163 |
| 36 | PIK3CG | 1.01985684 |
| 37 | DAPK1 | 1.00550833 |
| 38 | BLK | 0.99931600 |
| 39 | AKT3 | 0.99690601 |
| 40 | TEC | 0.97731260 |
| 41 | PLK3 | 0.96497236 |
| 42 | SYK | 0.95063625 |
| 43 | SCYL2 | 0.92800244 |
| 44 | TAOK3 | 0.87513401 |
| 45 | ZAP70 | 0.84305892 |
| 46 | BTK | 0.82885086 |
| 47 | EIF2AK3 | 0.79259300 |
| 48 | TYK2 | 0.77565282 |
| 49 | MAPKAPK5 | 0.77162070 |
| 50 | TRIM28 | 0.74121170 |
| 51 | CSK | 0.73076597 |
| 52 | BMPR2 | 0.70993689 |
| 53 | OXSR1 | 0.70596253 |
| 54 | JAK3 | 0.69865352 |
| 55 | RPS6KA5 | 0.69103119 |
| 56 | PDK2 | 0.67826807 |
| 57 | LCK | 0.66446830 |
| 58 | DAPK3 | 0.62898603 |
| 59 | MAP4K1 | 0.60815501 |
| 60 | GRK5 | 0.57545520 |
| 61 | MAPKAPK3 | 0.57432173 |
| 62 | SMG1 | 0.56697217 |
| 63 | MAPKAPK2 | 0.53617198 |
| 64 | TGFBR2 | 0.52318065 |
| 65 | HCK | 0.49663494 |
| 66 | PRKD3 | 0.44078989 |
| 67 | ITK | 0.43884635 |
| 68 | LYN | 0.43380068 |
| 69 | PAK3 | 0.43058086 |
| 70 | CAMK2G | 0.41848458 |
| 71 | MKNK1 | 0.41802171 |
| 72 | CHUK | 0.38439551 |
| 73 | SIK3 | 0.38013725 |
| 74 | LIMK1 | 0.37161947 |
| 75 | TBK1 | 0.35803061 |
| 76 | JAK1 | 0.32775863 |
| 77 | WNK3 | 0.32020615 |
| 78 | STK38L | 0.31980057 |
| 79 | DYRK2 | 0.30679562 |
| 80 | ILK | 0.30625833 |
| 81 | PRKCQ | 0.30121806 |
| 82 | CAMK2D | 0.30023134 |
| 83 | INSRR | 0.29467138 |
| 84 | FGFR3 | 0.29441674 |
| 85 | PRKCE | 0.28846204 |
| 86 | TAOK2 | 0.27722415 |
| 87 | PRKCG | 0.27298442 |
| 88 | BCKDK | 0.26277229 |
| 89 | PKN1 | 0.25623678 |
| 90 | TIE1 | 0.24724056 |
| 91 | CSNK1A1 | 0.24479393 |
| 92 | IGF1R | 0.24412577 |
| 93 | PIM1 | 0.24273203 |
| 94 | SRPK1 | 0.24110057 |
| 95 | GRK7 | 0.23846751 |
| 96 | ADRBK1 | 0.21171486 |
| 97 | ROCK1 | 0.20635094 |
| 98 | CHEK2 | 0.20157157 |
| 99 | MAPK13 | 0.19760396 |
| 100 | CDK7 | 0.17258357 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Proteasome_Homo sapiens_hsa03050 | 5.13255176 |
| 2 | Sulfur metabolism_Homo sapiens_hsa00920 | 4.46635728 |
| 3 | Primary immunodeficiency_Homo sapiens_hsa05340 | 3.60937808 |
| 4 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 3.24446827 |
| 5 | Parkinsons disease_Homo sapiens_hsa05012 | 2.71106782 |
| 6 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 2.38139005 |
| 7 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 2.33695742 |
| 8 | Nitrogen metabolism_Homo sapiens_hsa00910 | 2.17708041 |
| 9 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 2.16270365 |
| 10 | Antigen processing and presentation_Homo sapiens_hsa04612 | 2.14061738 |
| 11 | RNA polymerase_Homo sapiens_hsa03020 | 1.92093985 |
| 12 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.90289789 |
| 13 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.85245232 |
| 14 | Huntingtons disease_Homo sapiens_hsa05016 | 1.84346349 |
| 15 | RNA degradation_Homo sapiens_hsa03018 | 1.82206824 |
| 16 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.79175241 |
| 17 | Basal transcription factors_Homo sapiens_hsa03022 | 1.72953055 |
| 18 | Protein export_Homo sapiens_hsa03060 | 1.72887895 |
| 19 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 1.67686918 |
| 20 | Allograft rejection_Homo sapiens_hsa05330 | 1.65535417 |
| 21 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.64266541 |
| 22 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 1.50541406 |
| 23 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 1.50038901 |
| 24 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.49505438 |
| 25 | Alzheimers disease_Homo sapiens_hsa05010 | 1.41509290 |
| 26 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 1.41096587 |
| 27 | Ribosome_Homo sapiens_hsa03010 | 1.40589804 |
| 28 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.37006861 |
| 29 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 1.34804223 |
| 30 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.32466649 |
| 31 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.31504106 |
| 32 | Tryptophan metabolism_Homo sapiens_hsa00380 | 1.28821283 |
| 33 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.19102027 |
| 34 | Shigellosis_Homo sapiens_hsa05131 | 1.15131796 |
| 35 | Malaria_Homo sapiens_hsa05144 | 1.14594190 |
| 36 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 1.13282849 |
| 37 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.08241816 |
| 38 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 1.08056356 |
| 39 | Regulation of autophagy_Homo sapiens_hsa04140 | 1.06881360 |
| 40 | Folate biosynthesis_Homo sapiens_hsa00790 | 1.04144051 |
| 41 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.03308354 |
| 42 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 1.02350285 |
| 43 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.99421384 |
| 44 | Asthma_Homo sapiens_hsa05310 | 0.97382932 |
| 45 | Homologous recombination_Homo sapiens_hsa03440 | 0.93942542 |
| 46 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.93871974 |
| 47 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.93208027 |
| 48 | Phototransduction_Homo sapiens_hsa04744 | 0.90823028 |
| 49 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.90443977 |
| 50 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.88130953 |
| 51 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.80324502 |
| 52 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.79456797 |
| 53 | Measles_Homo sapiens_hsa05162 | 0.79046615 |
| 54 | Purine metabolism_Homo sapiens_hsa00230 | 0.77548331 |
| 55 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.76366917 |
| 56 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.72179464 |
| 57 | Peroxisome_Homo sapiens_hsa04146 | 0.69206912 |
| 58 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.68881265 |
| 59 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 0.68873889 |
| 60 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.67813892 |
| 61 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.65628423 |
| 62 | Sulfur relay system_Homo sapiens_hsa04122 | 0.64244887 |
| 63 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.64035118 |
| 64 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.63814004 |
| 65 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.62794626 |
| 66 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.62775086 |
| 67 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.57102890 |
| 68 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.56179720 |
| 69 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.56132997 |
| 70 | RNA transport_Homo sapiens_hsa03013 | 0.55962436 |
| 71 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.55243582 |
| 72 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.53649785 |
| 73 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.52018802 |
| 74 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 0.50280900 |
| 75 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 0.50081921 |
| 76 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.49671771 |
| 77 | Metabolic pathways_Homo sapiens_hsa01100 | 0.49010648 |
| 78 | Retinol metabolism_Homo sapiens_hsa00830 | 0.45540699 |
| 79 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.44637543 |
| 80 | HTLV-I infection_Homo sapiens_hsa05166 | 0.44572386 |
| 81 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.43817253 |
| 82 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.43587946 |
| 83 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.43091988 |
| 84 | Spliceosome_Homo sapiens_hsa03040 | 0.39987050 |
| 85 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.39031266 |
| 86 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.37639645 |
| 87 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.34590351 |
| 88 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.34072694 |
| 89 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.33199931 |
| 90 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.32241397 |
| 91 | Olfactory transduction_Homo sapiens_hsa04740 | 0.30128468 |
| 92 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.30126680 |
| 93 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.26838547 |
| 94 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.26528296 |
| 95 | Legionellosis_Homo sapiens_hsa05134 | 0.25710804 |
| 96 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.23507498 |
| 97 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.23189157 |
| 98 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.23181318 |
| 99 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.22112997 |
| 100 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.21485093 |

