Rank | Gene Set | Z-score |
---|---|---|
1 | synaptic vesicle maturation (GO:0016188) | 5.95038544 |
2 | locomotory exploration behavior (GO:0035641) | 5.83577459 |
3 | regulation of short-term neuronal synaptic plasticity (GO:0048172) | 5.79273533 |
4 | positive regulation of calcium ion-dependent exocytosis (GO:0045956) | 5.28776773 |
5 | positive regulation of excitatory postsynaptic membrane potential (GO:2000463) | 5.18941325 |
6 | vocalization behavior (GO:0071625) | 5.11185385 |
7 | layer formation in cerebral cortex (GO:0021819) | 5.01119189 |
8 | regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act | 4.81367938 |
9 | synaptic vesicle docking involved in exocytosis (GO:0016081) | 4.78391879 |
10 | glutamate secretion (GO:0014047) | 4.78281463 |
11 | synaptic vesicle exocytosis (GO:0016079) | 4.69722556 |
12 | regulation of glutamate receptor signaling pathway (GO:1900449) | 4.56530869 |
13 | regulation of synaptic vesicle exocytosis (GO:2000300) | 4.48983498 |
14 | exploration behavior (GO:0035640) | 4.38115285 |
15 | sodium ion export (GO:0071436) | 4.24841253 |
16 | regulation of synapse structural plasticity (GO:0051823) | 4.23780812 |
17 | protein localization to synapse (GO:0035418) | 4.16063892 |
18 | dendritic spine morphogenesis (GO:0060997) | 4.11483343 |
19 | neurotransmitter secretion (GO:0007269) | 4.06559639 |
20 | cellular potassium ion homeostasis (GO:0030007) | 4.02579945 |
21 | regulation of long-term neuronal synaptic plasticity (GO:0048169) | 4.00820623 |
22 | regulation of neuronal synaptic plasticity (GO:0048168) | 3.98905675 |
23 | proline transport (GO:0015824) | 3.96736957 |
24 | regulation of synaptic vesicle transport (GO:1902803) | 3.96642764 |
25 | ionotropic glutamate receptor signaling pathway (GO:0035235) | 3.92503391 |
26 | regulation of NFAT protein import into nucleus (GO:0051532) | 3.78854074 |
27 | activation of protein kinase A activity (GO:0034199) | 3.75072956 |
28 | positive regulation of synapse maturation (GO:0090129) | 3.70204144 |
29 | cell communication by electrical coupling involved in cardiac conduction (GO:0086064) | 3.54754687 |
30 | neurotransmitter-gated ion channel clustering (GO:0072578) | 3.54361306 |
31 | cell-cell junction maintenance (GO:0045217) | 3.52846179 |
32 | regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310) | 3.49823503 |
33 | neuron cell-cell adhesion (GO:0007158) | 3.49191242 |
34 | neuromuscular process controlling balance (GO:0050885) | 3.47026378 |
35 | cell communication by electrical coupling (GO:0010644) | 3.43983932 |
36 | long-term memory (GO:0007616) | 3.43025946 |
37 | synaptic transmission, glutamatergic (GO:0035249) | 3.41796364 |
38 | regulation of dendritic spine morphogenesis (GO:0061001) | 3.40937815 |
39 | gamma-aminobutyric acid transport (GO:0015812) | 3.39085549 |
40 | dendrite morphogenesis (GO:0048813) | 3.35663875 |
41 | glutamate receptor signaling pathway (GO:0007215) | 3.35458945 |
42 | neuronal action potential propagation (GO:0019227) | 3.33529462 |
43 | regulation of ARF protein signal transduction (GO:0032012) | 3.31042625 |
44 | membrane depolarization during cardiac muscle cell action potential (GO:0086012) | 3.31001906 |
45 | positive regulation of membrane potential (GO:0045838) | 3.30631779 |
46 | regulation of excitatory postsynaptic membrane potential (GO:0060079) | 3.25427725 |
47 | cytoskeletal anchoring at plasma membrane (GO:0007016) | 3.24134922 |
48 | synaptic vesicle endocytosis (GO:0048488) | 3.22812204 |
49 | apical protein localization (GO:0045176) | 3.21407731 |
50 | positive regulation of synaptic transmission, dopaminergic (GO:0032226) | 3.21325126 |
51 | G-protein coupled acetylcholine receptor signaling pathway (GO:0007213) | 3.20666276 |
52 | cerebellar Purkinje cell differentiation (GO:0021702) | 3.18454563 |
53 | neuron-neuron synaptic transmission (GO:0007270) | 3.15885414 |
54 | regulation of synaptic plasticity (GO:0048167) | 3.15402503 |
55 | cell migration in hindbrain (GO:0021535) | 3.14699604 |
56 | neuron recognition (GO:0008038) | 3.13956821 |
57 | cerebellar granule cell differentiation (GO:0021707) | 3.13083742 |
58 | regulation of postsynaptic membrane potential (GO:0060078) | 3.11482047 |
59 | regulation of clathrin-mediated endocytosis (GO:2000369) | 3.10856305 |
60 | neurotransmitter transport (GO:0006836) | 3.10566876 |
61 | axonal fasciculation (GO:0007413) | 3.10099488 |
62 | L-amino acid import (GO:0043092) | 3.09793564 |
63 | vesicle transport along microtubule (GO:0047496) | 3.09597004 |
64 | regulation of inhibitory postsynaptic membrane potential (GO:0060080) | 3.05231111 |
65 | auditory behavior (GO:0031223) | 3.04907440 |
66 | positive regulation of synaptic transmission, glutamatergic (GO:0051968) | 3.02758489 |
67 | cell communication involved in cardiac conduction (GO:0086065) | 3.02677583 |
68 | prepulse inhibition (GO:0060134) | 3.01447277 |
69 | cell junction maintenance (GO:0034331) | 3.00207410 |
70 | response to pheromone (GO:0019236) | 2.97219501 |
71 | dendritic spine organization (GO:0097061) | 2.96500315 |
72 | planar cell polarity pathway involved in neural tube closure (GO:0090179) | 2.94679370 |
73 | response to auditory stimulus (GO:0010996) | 2.93844027 |
74 | establishment of nucleus localization (GO:0040023) | 2.93671064 |
75 | innervation (GO:0060384) | 2.90132436 |
76 | response to histamine (GO:0034776) | 2.89600555 |
77 | regulation of neurotransmitter levels (GO:0001505) | 2.89183459 |
78 | cerebellar Purkinje cell layer development (GO:0021680) | 2.86632425 |
79 | positive regulation of synaptic transmission, GABAergic (GO:0032230) | 2.86089585 |
80 | regulation of early endosome to late endosome transport (GO:2000641) | 2.82808651 |
81 | mating behavior (GO:0007617) | 2.82658403 |
82 | amino acid import (GO:0043090) | 2.82123570 |
83 | regulation of neurotransmitter secretion (GO:0046928) | 2.81783987 |
84 | regulation of dendritic spine development (GO:0060998) | 2.81139590 |
85 | cellular sodium ion homeostasis (GO:0006883) | 2.80989880 |
86 | glycine transport (GO:0015816) | 2.80960994 |
87 | membrane hyperpolarization (GO:0060081) | 2.80624691 |
88 | potassium ion import (GO:0010107) | 2.79028689 |
89 | clathrin coat assembly (GO:0048268) | 2.77345698 |
90 | regulation of establishment of planar polarity involved in neural tube closure (GO:0090178) | 2.76163696 |
91 | positive regulation of potassium ion transmembrane transporter activity (GO:1901018) | 2.75981572 |
92 | intraspecies interaction between organisms (GO:0051703) | 2.75504413 |
93 | social behavior (GO:0035176) | 2.75504413 |
94 | organelle transport along microtubule (GO:0072384) | 2.74431017 |
95 | positive regulation of neurotransmitter secretion (GO:0001956) | 2.74340982 |
96 | central nervous system projection neuron axonogenesis (GO:0021952) | 2.74334858 |
97 | regulation of synaptic transmission, glutamatergic (GO:0051966) | 2.74327701 |
98 | membrane depolarization during action potential (GO:0086010) | 2.74210025 |
99 | dopamine receptor signaling pathway (GO:0007212) | 2.74017449 |
100 | long-term synaptic potentiation (GO:0060291) | 2.73626390 |
101 | regulation of vesicle fusion (GO:0031338) | 2.72620413 |
102 | positive regulation of neurotransmitter transport (GO:0051590) | 2.70320863 |
103 | neuron remodeling (GO:0016322) | 2.69434137 |
104 | neuronal ion channel clustering (GO:0045161) | 2.68014623 |
105 | membrane depolarization (GO:0051899) | 2.67569042 |
106 | neuromuscular process (GO:0050905) | 2.66554067 |
107 | synapse organization (GO:0050808) | 2.66097806 |
108 | synapse assembly (GO:0007416) | 2.65578079 |
109 | negative regulation of toll-like receptor 4 signaling pathway (GO:0034144) | 2.65533066 |
110 | positive regulation of dendritic spine morphogenesis (GO:0061003) | 2.64084217 |
111 | postsynaptic membrane organization (GO:0001941) | 2.64071761 |
112 | epithelial cell differentiation involved in prostate gland development (GO:0060742) | 2.62907271 |
113 | neuromuscular process controlling posture (GO:0050884) | 2.62227287 |
114 | negative regulation of amyloid precursor protein catabolic process (GO:1902992) | 2.61534796 |
115 | histone H3-K9 demethylation (GO:0033169) | 2.58962801 |
116 | epithelial cell-cell adhesion (GO:0090136) | 2.58836127 |
117 | regulation of water loss via skin (GO:0033561) | 2.57862403 |
118 | paraxial mesoderm development (GO:0048339) | 2.51598875 |
119 | adenylate cyclase-activating dopamine receptor signaling pathway (GO:0007191) | 2.51321866 |
120 | regulation of cholesterol homeostasis (GO:2000188) | 2.48680458 |
121 | desmosome organization (GO:0002934) | 2.47651942 |
122 | asymmetric protein localization (GO:0008105) | 2.47385014 |
123 | camera-type eye morphogenesis (GO:0048593) | 2.38368283 |
124 | establishment of skin barrier (GO:0061436) | 2.37850437 |
125 | multicellular organismal water homeostasis (GO:0050891) | 2.37761714 |
126 | embryonic retina morphogenesis in camera-type eye (GO:0060059) | 2.33415082 |
127 | phospholipase C-activating dopamine receptor signaling pathway (GO:0060158) | 2.30767959 |
128 | semaphorin-plexin signaling pathway (GO:0071526) | 2.28392707 |
129 | developmental cell growth (GO:0048588) | 2.26206211 |
130 | peptidyl-tyrosine autophosphorylation (GO:0038083) | 2.23644411 |
131 | positive regulation of transcription from RNA polymerase II promoter in response to stress (GO:00360 | 2.23451035 |
132 | protein localization to endosome (GO:0036010) | 2.16600493 |
133 | neuron projection extension (GO:1990138) | 2.16255517 |
134 | positive regulation of membrane protein ectodomain proteolysis (GO:0051044) | 2.13563122 |
135 | negative regulation of dendrite morphogenesis (GO:0050774) | 2.12675169 |
136 | signal complex assembly (GO:0007172) | 2.12011139 |
137 | establishment or maintenance of apical/basal cell polarity (GO:0035088) | 2.11730265 |
138 | establishment or maintenance of bipolar cell polarity (GO:0061245) | 2.11730265 |
139 | protein retention in ER lumen (GO:0006621) | 2.09401356 |
140 | cellular component maintenance (GO:0043954) | 2.09355161 |
141 | negative regulation of erythrocyte differentiation (GO:0045647) | 2.08760891 |
142 | regulation of transcription from RNA polymerase II promoter in response to oxidative stress (GO:0043 | 2.07018897 |
143 | cellular response to catecholamine stimulus (GO:0071870) | 2.06951413 |
144 | cellular response to monoamine stimulus (GO:0071868) | 2.06951413 |
145 | cellular response to prostaglandin stimulus (GO:0071379) | 2.03302280 |
146 | axon extension (GO:0048675) | 2.02617950 |
147 | adherens junction assembly (GO:0034333) | 2.02323795 |
148 | negative regulation of fatty acid transport (GO:2000192) | 2.02099620 |
149 | respiratory system process (GO:0003016) | 2.01853574 |
150 | water homeostasis (GO:0030104) | 2.00766033 |
151 | activation of MAPKKK activity (GO:0000185) | 2.00607445 |
152 | response to mercury ion (GO:0046689) | 2.00288385 |
153 | receptor recycling (GO:0001881) | 1.99692661 |
154 | skeletal muscle organ development (GO:0060538) | 1.98812726 |
155 | vitamin transmembrane transport (GO:0035461) | 1.98566711 |
156 | response to laminar fluid shear stress (GO:0034616) | 1.98094742 |
157 | maintenance of protein localization in endoplasmic reticulum (GO:0035437) | 1.97935453 |
158 | sodium ion homeostasis (GO:0055078) | 1.97899866 |
Rank | Gene Set | Z-score |
---|---|---|
1 | EZH2_22144423_ChIP-Seq_EOC_Human | 4.76820743 |
2 | RARB_27405468_Chip-Seq_BRAIN_Mouse | 2.66024132 |
3 | DROSHA_22980978_ChIP-Seq_HELA_Human | 2.61130411 |
4 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 2.60941629 |
5 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 2.58778682 |
6 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 2.52052017 |
7 | * EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 2.51921196 |
8 | EZH2_18974828_ChIP-Seq_MESCs_Mouse | 2.43569868 |
9 | RNF2_18974828_ChIP-Seq_MESCs_Mouse | 2.43569868 |
10 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 2.42765206 |
11 | REST_21632747_ChIP-Seq_MESCs_Mouse | 2.31500364 |
12 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 2.29127281 |
13 | SUZ12_20075857_ChIP-Seq_MESCs_Mouse | 2.27124192 |
14 | MTF2_20144788_ChIP-Seq_MESCs_Mouse | 2.27040223 |
15 | MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human | 2.20254782 |
16 | SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 2.15701213 |
17 | GBX2_23144817_ChIP-Seq_PC3_Human | 2.11040556 |
18 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 2.09127326 |
19 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 2.06924211 |
20 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 2.05385247 |
21 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 2.05093104 |
22 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 2.03173117 |
23 | RNF2_27304074_Chip-Seq_ESCs_Mouse | 2.01827622 |
24 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 1.97717620 |
25 | * REST_18959480_ChIP-ChIP_MESCs_Mouse | 1.90787047 |
26 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 1.83474676 |
27 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 1.79055434 |
28 | AR_21572438_ChIP-Seq_LNCaP_Human | 1.77880506 |
29 | ZFP281_18757296_ChIP-ChIP_E14_Mouse | 1.77536376 |
30 | ERG_21242973_ChIP-ChIP_JURKAT_Human | 1.73141285 |
31 | ESR1_21235772_ChIP-Seq_MCF-7_Human | 1.72295791 |
32 | * KDM2B_26808549_Chip-Seq_K562_Human | 1.71848900 |
33 | TFAP2C_20629094_ChIP-Seq_MCF-7_Human | 1.69005104 |
34 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 1.68246478 |
35 | WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse | 1.60801072 |
36 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 1.59171871 |
37 | DNAJC2_21179169_ChIP-ChIP_NT2_Human | 1.58440218 |
38 | * RACK7_27058665_Chip-Seq_MCF-7_Human | 1.48362335 |
39 | TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse | 1.48155290 |
40 | * EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human | 1.47417005 |
41 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 1.45011730 |
42 | CLOCK_20551151_ChIP-Seq_293T_Human | 1.44892045 |
43 | TCF3_18467660_ChIP-ChIP_MESCs_Mouse | 1.44561503 |
44 | KLF2_18264089_ChIP-ChIP_MESCs_Mouse | 1.43669361 |
45 | KLF5_18264089_ChIP-ChIP_MESCs_Mouse | 1.43669361 |
46 | KLF4_18264089_ChIP-ChIP_MESCs_Mouse | 1.43669361 |
47 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.43327234 |
48 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 1.43314645 |
49 | * ZFP281_27345836_Chip-Seq_ESCs_Mouse | 1.40148989 |
50 | * WT1_25993318_ChIP-Seq_PODOCYTE_Human | 1.39836557 |
51 | RING1B_27294783_Chip-Seq_ESCs_Mouse | 1.37529241 |
52 | ZNF217_24962896_ChIP-Seq_MCF-7_Human | 1.33334700 |
53 | * SMAD3_22036565_ChIP-Seq_ESCs_Mouse | 1.33265714 |
54 | RCOR3_21632747_ChIP-Seq_MESCs_Mouse | 1.29789115 |
55 | TCF7_22412390_ChIP-Seq_EML_Mouse | 1.29553492 |
56 | FOXO1_23066095_ChIP-Seq_LIVER_Mouse | 1.27802423 |
57 | GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.27617636 |
58 | ESR1_17901129_ChIP-ChIP_LIVER_Mouse | 1.24468786 |
59 | TRIM28_21343339_ChIP-Seq_HEK293_Human | 1.24045043 |
60 | AR_19668381_ChIP-Seq_PC3_Human | 1.23277774 |
61 | RING1B_27294783_Chip-Seq_NPCs_Mouse | 1.22746738 |
62 | NFIB_24661679_ChIP-Seq_LUNG_Mouse | 1.21888642 |
63 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 1.21140003 |
64 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.21090460 |
65 | SOX2_21211035_ChIP-Seq_LN229_Gbm | 1.20055538 |
66 | * CDX2_20551321_ChIP-Seq_CACO-2_Human | 1.19736612 |
67 | AHR_22903824_ChIP-Seq_MCF-7_Human | 1.18589778 |
68 | KDM2B_26808549_Chip-Seq_DND41_Human | 1.17128065 |
69 | KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 1.16852178 |
70 | * SOX9_24532713_ChIP-Seq_HFSC_Mouse | 1.16607905 |
71 | * SOX2_27498859_Chip-Seq_STOMACH_Mouse | 1.16335540 |
72 | RUNX1_27514584_Chip-Seq_MCF-7_Human | 1.15295762 |
73 | DMRT1_23473982_ChIP-Seq_TESTES_Mouse | 1.14505099 |
74 | ARNT_22903824_ChIP-Seq_MCF-7_Human | 1.13335522 |
75 | LXR_22292898_ChIP-Seq_THP-1_Human | 1.13311761 |
76 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 1.12713841 |
77 | SMAD4_21799915_ChIP-Seq_A2780_Human | 1.11610918 |
78 | NR3C1_23031785_ChIP-Seq_PC12_Mouse | 1.11083179 |
79 | NR1I2_20693526_ChIP-Seq_LIVER_Mouse | 1.10963192 |
80 | KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.10633645 |
81 | * KDM2B_26808549_Chip-Seq_JURKAT_Human | 1.10402971 |
82 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 1.09862587 |
83 | * TP53_20018659_ChIP-ChIP_R1E_Mouse | 1.09363515 |
84 | CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 1.09092396 |
85 | RARG_19884340_ChIP-ChIP_MEFs_Mouse | 1.08805144 |
86 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.08282904 |
87 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 1.07813357 |
88 | * CREB1_26743006_Chip-Seq_LNCaP-abl_Human | 1.07491836 |
89 | UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human | 1.07323376 |
90 | ESR1_20079471_ChIP-ChIP_T-47D_Human | 1.06531554 |
91 | P300_27058665_Chip-Seq_ZR-75-30cells_Human | 1.05962478 |
92 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 1.05399597 |
93 | ZFP281_18358816_ChIP-ChIP_MESCs_Mouse | 1.05291839 |
94 | ZNF263_19887448_ChIP-Seq_K562_Human | 1.04184371 |
95 | * CTCF_27219007_Chip-Seq_Bcells_Human | 1.04066039 |
96 | GATA1_26923725_Chip-Seq_HPCs_Mouse | 1.03024485 |
97 | RCOR2_21632747_ChIP-Seq_MESCs_Mouse | 1.02454749 |
98 | ISL1_27105846_Chip-Seq_CPCs_Mouse | 1.01731629 |
99 | OLIG2_26023283_ChIP-Seq_AINV15_Mouse | 1.01237738 |
100 | ELK3_25401928_ChIP-Seq_HUVEC_Human | 1.01152487 |
101 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 1.00357233 |
102 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.00200550 |
103 | P53_22127205_ChIP-Seq_FIBROBLAST_Human | 1.00003706 |
104 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 0.99851679 |
105 | RXR_22108803_ChIP-Seq_LS180_Human | 0.99545283 |
106 | YAP1_20516196_ChIP-Seq_MESCs_Mouse | 0.99443526 |
107 | FOXA2_19822575_ChIP-Seq_HepG2_Human | 0.98924079 |
108 | FOXO3_23340844_ChIP-Seq_DLD1_Human | 0.98258435 |
109 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 0.98062748 |
110 | SMAD4_21741376_ChIP-Seq_HESCs_Human | 0.97869139 |
111 | TP53_16413492_ChIP-PET_HCT116_Human | 0.97729894 |
112 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 0.97370928 |
113 | SMAD3_21741376_ChIP-Seq_HESCs_Human | 0.96804085 |
114 | TET1_21490601_ChIP-Seq_MESCs_Mouse | 0.94224543 |
115 | KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human | 0.94089953 |
116 | ESRRB_18555785_ChIP-Seq_MESCs_Mouse | 0.93722162 |
117 | SALL4_18804426_ChIP-ChIP_MESCs_Mouse | 0.93112992 |
118 | ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 0.93058417 |
119 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 0.93010041 |
120 | AR_25329375_ChIP-Seq_VCAP_Human | 0.92989817 |
121 | SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse | 0.92753818 |
122 | LXR_22158963_ChIP-Seq_LIVER_Mouse | 0.92349896 |
123 | CREB1_26743006_Chip-Seq_LNCaP_Human | 0.92133965 |
124 | SMAD3_21741376_ChIP-Seq_ESCs_Human | 0.91783145 |
125 | KLF5_25053715_ChIP-Seq_YYC3_Human | 0.91255769 |
126 | BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human | 0.90977959 |
127 | RXR_22158963_ChIP-Seq_LIVER_Mouse | 0.90612934 |
128 | SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.90532066 |
129 | ESR1_22446102_ChIP-Seq_UTERUS_Mouse | 0.89902041 |
130 | EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse | 0.89023029 |
131 | STAT3_23295773_ChIP-Seq_U87_Human | 0.87832942 |
132 | TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.85910745 |
133 | SMC4_20622854_ChIP-Seq_HELA_Human | 0.85604643 |
134 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 0.84973508 |
135 | CTNNB1_20460455_ChIP-Seq_HCT116_Human | 0.84930361 |
136 | TFAP2A_17053090_ChIP-ChIP_MCF-7_Human | 0.84303524 |
137 | RNF2_16625203_ChIP-ChIP_MESCs_Mouse | 0.83878065 |
138 | PHC1_16625203_ChIP-ChIP_MESCs_Mouse | 0.81630574 |
139 | CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human | 0.80894858 |
140 | * VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 0.80595399 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0004859_abnormal_synaptic_plasticity | 7.15816210 |
2 | MP0003635_abnormal_synaptic_transmissio | 4.10360143 |
3 | MP0004270_analgesia | 3.77350225 |
4 | MP0003880_abnormal_central_pattern | 3.67972564 |
5 | MP0000566_synostosis | 3.45660641 |
6 | MP0005409_darkened_coat_color | 3.30731972 |
7 | MP0002063_abnormal_learning/memory/cond | 3.27183063 |
8 | MP0009745_abnormal_behavioral_response | 3.00222927 |
9 | MP0002822_catalepsy | 2.99036281 |
10 | MP0010234_abnormal_vibrissa_follicle | 2.88353283 |
11 | MP0002064_seizures | 2.76804256 |
12 | MP0009046_muscle_twitch | 2.66006641 |
13 | MP0004858_abnormal_nervous_system | 2.58773172 |
14 | MP0005423_abnormal_somatic_nervous | 2.58582026 |
15 | MP0002572_abnormal_emotion/affect_behav | 2.49710397 |
16 | MP0002139_abnormal_hepatobiliary_system | 2.30019322 |
17 | MP0002734_abnormal_mechanical_nocicepti | 2.26740048 |
18 | MP0009780_abnormal_chondrocyte_physiolo | 2.26135793 |
19 | MP0001968_abnormal_touch/_nociception | 2.24550786 |
20 | MP0001486_abnormal_startle_reflex | 2.18379247 |
21 | MP0001501_abnormal_sleep_pattern | 2.15526414 |
22 | MP0002909_abnormal_adrenal_gland | 2.08081637 |
23 | MP0008004_abnormal_stomach_pH | 2.00209251 |
24 | MP0003329_amyloid_beta_deposits | 1.99483698 |
25 | MP0003453_abnormal_keratinocyte_physiol | 1.99355851 |
26 | MP0002272_abnormal_nervous_system | 1.94247068 |
27 | MP0004811_abnormal_neuron_physiology | 1.92590052 |
28 | MP0003183_abnormal_peptide_metabolism | 1.91952446 |
29 | MP0001440_abnormal_grooming_behavior | 1.86860731 |
30 | MP0002249_abnormal_larynx_morphology | 1.86706205 |
31 | MP0000778_abnormal_nervous_system | 1.85662292 |
32 | MP0009379_abnormal_foot_pigmentation | 1.84906942 |
33 | MP0008569_lethality_at_weaning | 1.84273773 |
34 | MP0002733_abnormal_thermal_nociception | 1.82766699 |
35 | MP0004885_abnormal_endolymph | 1.76019991 |
36 | MP0009840_abnormal_foam_cell | 1.75468382 |
37 | MP0010352_gastrointestinal_tract_polyps | 1.74761266 |
38 | MP0008961_abnormal_basal_metabolism | 1.74119777 |
39 | MP0000569_abnormal_digit_pigmentation | 1.70145600 |
40 | MP0002184_abnormal_innervation | 1.64462148 |
41 | MP0000678_abnormal_parathyroid_gland | 1.63015177 |
42 | MP0001970_abnormal_pain_threshold | 1.61373741 |
43 | MP0002557_abnormal_social/conspecific_i | 1.61095830 |
44 | MP0005386_behavior/neurological_phenoty | 1.55314249 |
45 | MP0004924_abnormal_behavior | 1.55314249 |
46 | MP0003283_abnormal_digestive_organ | 1.54013212 |
47 | MP0000751_myopathy | 1.53259922 |
48 | MP0005666_abnormal_adipose_tissue | 1.52684476 |
49 | MP0000955_abnormal_spinal_cord | 1.52128973 |
50 | MP0005058_abnormal_lysosome_morphology | 1.51484597 |
51 | MP0002735_abnormal_chemical_nociception | 1.50315474 |
52 | MP0003890_abnormal_embryonic-extraembry | 1.48961163 |
53 | MP0002067_abnormal_sensory_capabilities | 1.48485167 |
54 | MP0002736_abnormal_nociception_after | 1.46276886 |
55 | MP0005451_abnormal_body_composition | 1.46131161 |
56 | * MP0005076_abnormal_cell_differentiation | 1.42499705 |
57 | MP0003879_abnormal_hair_cell | 1.41839326 |
58 | MP0003300_gastrointestinal_ulcer | 1.41518492 |
59 | MP0005365_abnormal_bile_salt | 1.39577216 |
60 | MP0002098_abnormal_vibrissa_morphology | 1.39043321 |
61 | MP0005167_abnormal_blood-brain_barrier | 1.37375653 |
62 | MP0004264_abnormal_extraembryonic_tissu | 1.36563472 |
63 | MP0003633_abnormal_nervous_system | 1.35062861 |
64 | MP0002882_abnormal_neuron_morphology | 1.32448538 |
65 | MP0010030_abnormal_orbit_morphology | 1.31170438 |
66 | MP0001188_hyperpigmentation | 1.30631682 |
67 | MP0002066_abnormal_motor_capabilities/c | 1.26369721 |
68 | MP0005248_abnormal_Harderian_gland | 1.25848887 |
69 | MP0003075_altered_response_to | 1.24806325 |
70 | MP0004130_abnormal_muscle_cell | 1.23326466 |
71 | MP0001666_abnormal_nutrient_absorption | 1.20239066 |
72 | MP0003787_abnormal_imprinting | 1.16807043 |
73 | MP0004233_abnormal_muscle_weight | 1.16646088 |
74 | MP0002896_abnormal_bone_mineralization | 1.15731692 |
75 | MP0003091_abnormal_cell_migration | 1.12914628 |
76 | MP0003868_abnormal_feces_composition | 1.12249173 |
77 | MP0004145_abnormal_muscle_electrophysio | 1.12004632 |
78 | MP0005501_abnormal_skin_physiology | 1.12000592 |
79 | MP0001346_abnormal_lacrimal_gland | 1.11467951 |
80 | MP0003123_paternal_imprinting | 1.10085406 |
81 | * MP0002152_abnormal_brain_morphology | 1.09423683 |
82 | MP0002653_abnormal_ependyma_morphology | 1.09410887 |
83 | MP0003122_maternal_imprinting | 1.09081111 |
84 | MP0001984_abnormal_olfaction | 1.08253018 |
85 | MP0001502_abnormal_circadian_rhythm | 1.07983421 |
86 | MP0003631_nervous_system_phenotype | 1.07036173 |
87 | MP0003705_abnormal_hypodermis_morpholog | 1.05850007 |
88 | MP0000462_abnormal_digestive_system | 1.04446523 |
89 | MP0005187_abnormal_penis_morphology | 1.03977424 |
90 | MP0000604_amyloidosis | 1.03614127 |
91 | MP0005360_urolithiasis | 1.03328521 |
92 | MP0003303_peritoneal_inflammation | 1.02082551 |
93 | MP0001177_atelectasis | 1.00488066 |
94 | MP0004043_abnormal_pH_regulation | 0.99071108 |
95 | MP0005085_abnormal_gallbladder_physiolo | 0.98869399 |
96 | MP0002069_abnormal_eating/drinking_beha | 0.93461750 |
97 | MP0004510_myositis | 0.92839028 |
98 | MP0008874_decreased_physiological_sensi | 0.92473269 |
99 | MP0005645_abnormal_hypothalamus_physiol | 0.90443581 |
100 | MP0006276_abnormal_autonomic_nervous | 0.88898791 |
101 | MP0003941_abnormal_skin_development | 0.88102512 |
102 | MP0005646_abnormal_pituitary_gland | 0.87421967 |
103 | MP0004019_abnormal_vitamin_homeostasis | 0.86227291 |
104 | MP0000920_abnormal_myelination | 0.85136799 |
105 | MP0005499_abnormal_olfactory_system | 0.82594187 |
106 | MP0005394_taste/olfaction_phenotype | 0.82594187 |
107 | MP0009672_abnormal_birth_weight | 0.81319022 |
108 | MP0008872_abnormal_physiological_respon | 0.80866905 |
109 | MP0003191_abnormal_cellular_cholesterol | 0.80302344 |
110 | MP0002796_impaired_skin_barrier | 0.79294915 |
111 | MP0005375_adipose_tissue_phenotype | 0.79084135 |
112 | MP0000537_abnormal_urethra_morphology | 0.78845977 |
113 | MP0004085_abnormal_heartbeat | 0.78524111 |
114 | MP0003566_abnormal_cell_adhesion | 0.78039460 |
115 | MP0004947_skin_inflammation | 0.77683167 |
116 | MP0002234_abnormal_pharynx_morphology | 0.77367131 |
117 | MP0003632_abnormal_nervous_system | 0.74973291 |
118 | MP0005257_abnormal_intraocular_pressure | 0.74836993 |
119 | MP0003634_abnormal_glial_cell | 0.74020289 |
120 | MP0003690_abnormal_glial_cell | 0.73568468 |
121 | MP0003938_abnormal_ear_development | 0.73254131 |
122 | MP0002229_neurodegeneration | 0.73131350 |
123 | MP0003172_abnormal_lysosome_physiology | 0.72708775 |
124 | MP0005535_abnormal_body_temperature | 0.71800823 |
125 | MP0003045_fibrosis | 0.71118951 |
126 | MP0002090_abnormal_vision | 0.70606164 |
127 | MP0004484_altered_response_of | 0.70456449 |
128 | MP0004782_abnormal_surfactant_physiolog | 0.69970952 |
129 | MP0009278_abnormal_bone_marrow | 0.68799311 |
130 | MP0000383_abnormal_hair_follicle | 0.68428866 |
131 | MP0001849_ear_inflammation | 0.68031490 |
132 | MP0000013_abnormal_adipose_tissue | 0.67577805 |
133 | MP0005623_abnormal_meninges_morphology | 0.65681577 |
134 | MP0000747_muscle_weakness | 0.64631393 |
135 | MP0002089_abnormal_postnatal_growth/wei | 0.64075393 |
136 | MP0005166_decreased_susceptibility_to | 0.63513180 |
137 | * MP0003861_abnormal_nervous_system | 0.63419428 |
138 | MP0001664_abnormal_digestion | 0.62887991 |
139 | MP0004215_abnormal_myocardial_fiber | 0.61612033 |
140 | MP0003646_muscle_fatigue | 0.61441657 |
141 | MP0000534_abnormal_ureter_morphology | 0.61334928 |
142 | MP0000579_abnormal_nail_morphology | 0.59725543 |
143 | MP0004185_abnormal_adipocyte_glucose | 0.58409592 |
144 | MP0005551_abnormal_eye_electrophysiolog | 0.57615207 |
145 | MP0001943_abnormal_respiration | 0.57270840 |
146 | MP0010769_abnormal_survival | 0.56504548 |
147 | MP0005620_abnormal_muscle_contractility | 0.55840464 |
148 | MP0010678_abnormal_skin_adnexa | 0.54999883 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Myokymia (HP:0002411) | 5.68245057 |
2 | Focal motor seizures (HP:0011153) | 5.36413346 |
3 | Visual hallucinations (HP:0002367) | 4.62679188 |
4 | Focal seizures (HP:0007359) | 4.59381153 |
5 | Supranuclear gaze palsy (HP:0000605) | 3.57279428 |
6 | Action tremor (HP:0002345) | 3.55476332 |
7 | Papilledema (HP:0001085) | 3.45140630 |
8 | Epileptic encephalopathy (HP:0200134) | 3.43746729 |
9 | Ankle clonus (HP:0011448) | 3.24807871 |
10 | Absence seizures (HP:0002121) | 3.18360668 |
11 | Poor eye contact (HP:0000817) | 3.10826287 |
12 | Abnormality of the lower motor neuron (HP:0002366) | 3.09621917 |
13 | Progressive cerebellar ataxia (HP:0002073) | 3.09602427 |
14 | Mutism (HP:0002300) | 3.06979783 |
15 | Impaired vibration sensation in the lower limbs (HP:0002166) | 3.06169452 |
16 | Impaired social interactions (HP:0000735) | 3.04726646 |
17 | Abnormal social behavior (HP:0012433) | 3.04726646 |
18 | Urinary bladder sphincter dysfunction (HP:0002839) | 3.02480670 |
19 | Generalized tonic-clonic seizures (HP:0002069) | 2.97801340 |
20 | Atonic seizures (HP:0010819) | 2.97190535 |
21 | Febrile seizures (HP:0002373) | 2.90908981 |
22 | Depression (HP:0000716) | 2.88000790 |
23 | Broad-based gait (HP:0002136) | 2.79586221 |
24 | Dysmetric saccades (HP:0000641) | 2.75921877 |
25 | Dialeptic seizures (HP:0011146) | 2.75457803 |
26 | Postural instability (HP:0002172) | 2.75127438 |
27 | Flat acetabular roof (HP:0003180) | 2.74245098 |
28 | Urinary urgency (HP:0000012) | 2.73677055 |
29 | Hyperparathyroidism (HP:0000843) | 2.73321086 |
30 | Ventricular fibrillation (HP:0001663) | 2.72584683 |
31 | Thin bony cortex (HP:0002753) | 2.70680487 |
32 | Genetic anticipation (HP:0003743) | 2.70522221 |
33 | Hyperactive renin-angiotensin system (HP:0000841) | 2.70129351 |
34 | Dysdiadochokinesis (HP:0002075) | 2.62638379 |
35 | Cerebral inclusion bodies (HP:0100314) | 2.60480935 |
36 | Abnormality of monocarboxylic acid metabolism (HP:0010996) | 2.54852550 |
37 | Pointed chin (HP:0000307) | 2.54816322 |
38 | Abnormal eating behavior (HP:0100738) | 2.53694091 |
39 | Ankyloglossia (HP:0010296) | 2.49718501 |
40 | Torticollis (HP:0000473) | 2.47419609 |
41 | Insomnia (HP:0100785) | 2.45896008 |
42 | Amblyopia (HP:0000646) | 2.45766513 |
43 | Excessive salivation (HP:0003781) | 2.44197861 |
44 | Drooling (HP:0002307) | 2.44197861 |
45 | Hemiplegia (HP:0002301) | 2.41242141 |
46 | Stereotypic behavior (HP:0000733) | 2.41137936 |
47 | Truncal ataxia (HP:0002078) | 2.38752978 |
48 | Malnutrition (HP:0004395) | 2.38385084 |
49 | Hypercortisolism (HP:0001578) | 2.38114342 |
50 | Megalencephaly (HP:0001355) | 2.37671842 |
51 | Intention tremor (HP:0002080) | 2.37300384 |
52 | Obstructive sleep apnea (HP:0002870) | 2.36317957 |
53 | Exercise-induced myalgia (HP:0003738) | 2.35279828 |
54 | Hyperacusis (HP:0010780) | 2.33544106 |
55 | Impaired smooth pursuit (HP:0007772) | 2.33412744 |
56 | Dysmetria (HP:0001310) | 2.32436926 |
57 | Gaze-evoked nystagmus (HP:0000640) | 2.31466293 |
58 | Neurofibrillary tangles (HP:0002185) | 2.29498065 |
59 | Right ventricular cardiomyopathy (HP:0011663) | 2.28646416 |
60 | Amyotrophic lateral sclerosis (HP:0007354) | 2.28629441 |
61 | Insidious onset (HP:0003587) | 2.27767427 |
62 | Termporal pattern (HP:0011008) | 2.27767427 |
63 | Bundle branch block (HP:0011710) | 2.26292803 |
64 | Anxiety (HP:0000739) | 2.25899747 |
65 | Annular pancreas (HP:0001734) | 2.25840827 |
66 | Osteomalacia (HP:0002749) | 2.25808075 |
67 | Apathy (HP:0000741) | 2.24827424 |
68 | Bronchomalacia (HP:0002780) | 2.23781000 |
69 | Inappropriate behavior (HP:0000719) | 2.23075250 |
70 | Focal dystonia (HP:0004373) | 2.18191856 |
71 | Abnormality of the distal phalanx of the thumb (HP:0009617) | 2.17532116 |
72 | Hemiparesis (HP:0001269) | 2.17297677 |
73 | Diplopia (HP:0000651) | 2.14232609 |
74 | Abnormality of binocular vision (HP:0011514) | 2.14232609 |
75 | Shallow orbits (HP:0000586) | 2.13380224 |
76 | Aplasia involving bones of the extremities (HP:0009825) | 2.10708044 |
77 | Aplasia involving bones of the upper limbs (HP:0009823) | 2.10708044 |
78 | Aplasia of the phalanges of the hand (HP:0009802) | 2.10708044 |
79 | Spastic gait (HP:0002064) | 2.10072598 |
80 | Abnormality of the corticospinal tract (HP:0002492) | 2.07960067 |
81 | Deep venous thrombosis (HP:0002625) | 2.05071761 |
82 | Lower limb amyotrophy (HP:0007210) | 2.04610921 |
83 | Rapidly progressive (HP:0003678) | 2.03444342 |
84 | Vertebral arch anomaly (HP:0008438) | 2.03437246 |
85 | Macroorchidism (HP:0000053) | 2.02751714 |
86 | Abnormality of ocular smooth pursuit (HP:0000617) | 2.02377605 |
87 | Abnormality of the salivary glands (HP:0010286) | 2.01446206 |
88 | Elfin facies (HP:0004428) | 2.01015595 |
89 | Bradykinesia (HP:0002067) | 2.00706772 |
90 | Lower limb muscle weakness (HP:0007340) | 1.99708802 |
91 | Adrenal overactivity (HP:0002717) | 1.99669236 |
92 | Diminished motivation (HP:0000745) | 1.98168518 |
93 | Turricephaly (HP:0000262) | 1.96236946 |
94 | Craniofacial dystonia (HP:0012179) | 1.95442144 |
95 | Status epilepticus (HP:0002133) | 1.94685110 |
96 | Neonatal short-limb short stature (HP:0008921) | 1.94107348 |
97 | Neuronal loss in central nervous system (HP:0002529) | 1.94043219 |
98 | Agitation (HP:0000713) | 1.93975778 |
99 | Intellectual disability, profound (HP:0002187) | 1.93681735 |
100 | Impaired vibratory sensation (HP:0002495) | 1.90985715 |
101 | Loss of speech (HP:0002371) | 1.89428615 |
102 | Neoplasm of the heart (HP:0100544) | 1.86992753 |
103 | Abnormality of oral frenula (HP:0000190) | 1.86212449 |
104 | Resting tremor (HP:0002322) | 1.86173521 |
105 | Difficulty running (HP:0009046) | 1.84986131 |
106 | Systemic lupus erythematosus (HP:0002725) | 1.84842604 |
107 | Polyphagia (HP:0002591) | 1.84433869 |
108 | Lower limb asymmetry (HP:0100559) | 1.83533448 |
109 | Partial duplication of thumb phalanx (HP:0009944) | 1.83435228 |
110 | Sudden death (HP:0001699) | 1.83375272 |
111 | Achilles tendon contracture (HP:0001771) | 1.82930223 |
112 | Epileptiform EEG discharges (HP:0011182) | 1.82688407 |
113 | Disinhibition (HP:0000734) | 1.82606727 |
114 | Scanning speech (HP:0002168) | 1.79312078 |
115 | EEG with generalized epileptiform discharges (HP:0011198) | 1.79225631 |
116 | Spinal cord compression (HP:0002176) | 1.79062864 |
117 | Hyperventilation (HP:0002883) | 1.78300673 |
118 | Arnold-Chiari malformation (HP:0002308) | 1.78116189 |
119 | Hammertoe (HP:0001765) | 1.76500224 |
120 | Broad metatarsal (HP:0001783) | 1.76160268 |
121 | Elevated circulating parathyroid hormone (PTH) level (HP:0003165) | 1.75439235 |
122 | Hypsarrhythmia (HP:0002521) | 1.74975674 |
123 | Upper limb amyotrophy (HP:0009129) | 1.72292758 |
124 | Distal upper limb amyotrophy (HP:0007149) | 1.72292758 |
125 | Abnormal EKG (HP:0003115) | 1.71597762 |
126 | Syncope (HP:0001279) | 1.71534662 |
127 | Thickened helices (HP:0000391) | 1.71154981 |
128 | Clonus (HP:0002169) | 1.70786946 |
129 | Complement deficiency (HP:0004431) | 1.70781872 |
130 | Abnormality of the astrocytes (HP:0100707) | 1.70715354 |
131 | Astrocytoma (HP:0009592) | 1.70715354 |
132 | Visceral angiomatosis (HP:0100761) | 1.70188464 |
133 | Increased circulating renin level (HP:0000848) | 1.68192287 |
134 | Bowel incontinence (HP:0002607) | 1.67748653 |
135 | Abnormality of calcium-phosphate metabolism (HP:0100530) | 1.67405201 |
136 | Germ cell neoplasia (HP:0100728) | 1.67217925 |
137 | Amyloidosis (HP:0011034) | 1.66869195 |
138 | Glomerulonephritis (HP:0000099) | 1.66762110 |
139 | Taurodontia (HP:0000679) | 1.65793717 |
140 | Abnormality of permanent molar morphology (HP:0011071) | 1.65793717 |
141 | Abnormality of the dental root (HP:0006486) | 1.65793717 |
142 | Hypercalciuria (HP:0002150) | 1.61955407 |
143 | Hypophosphatemia (HP:0002148) | 1.61447453 |
144 | Hyperaldosteronism (HP:0000859) | 1.61224130 |
145 | Abnormality of the aortic arch (HP:0012303) | 1.61004988 |
146 | Nuclear cataract (HP:0100018) | 1.60748051 |
147 | Axonal loss (HP:0003447) | 1.59596386 |
148 | Peripheral hypomyelination (HP:0007182) | 1.58447792 |
149 | Arterial tortuosity (HP:0005116) | 1.58004697 |
150 | Onion bulb formation (HP:0003383) | 1.57845129 |
151 | Segmental peripheral demyelination/remyelination (HP:0003481) | 1.55971674 |
152 | Bone pain (HP:0002653) | 1.54674038 |
153 | Abnormality of molar morphology (HP:0011070) | 1.54022575 |
154 | Abnormality of molar (HP:0011077) | 1.54022575 |
155 | Rickets (HP:0002748) | 1.53935007 |
156 | Abnormal large intestine physiology (HP:0012700) | 1.53423157 |
157 | Esophageal varix (HP:0002040) | 1.52422950 |
158 | Papillary thyroid carcinoma (HP:0002895) | 1.52338353 |
159 | Cerebral aneurysm (HP:0004944) | 1.52252128 |
160 | Sleep apnea (HP:0010535) | 1.52204897 |
161 | Vascular tortuosity (HP:0004948) | 1.52061566 |
162 | Hemorrhage of the eye (HP:0011885) | 1.52050238 |
163 | Neonatal death (HP:0003811) | 1.50863988 |
164 | Hemangiomatosis (HP:0007461) | 1.48976472 |
165 | Widely patent fontanelles and sutures (HP:0004492) | 1.48578096 |
166 | Dementia (HP:0000726) | 1.48492030 |
167 | Delayed epiphyseal ossification (HP:0002663) | 1.48309210 |
168 | Partial duplication of the phalanx of hand (HP:0009999) | 1.46633639 |
169 | Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204) | 1.46459853 |
170 | Renovascular hypertension (HP:0100817) | 1.45876218 |
171 | Abnormality of complement system (HP:0005339) | 1.45164679 |
172 | Abnormality of chloride homeostasis (HP:0011422) | 1.44325129 |
173 | Hypercalcemia (HP:0003072) | 1.43514002 |
174 | Broad face (HP:0000283) | 1.43397768 |
175 | Ulnar bowing (HP:0003031) | 1.43333381 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MAP3K9 | 4.48024882 |
2 | EPHA4 | 3.69095282 |
3 | MARK1 | 3.66044580 |
4 | NTRK3 | 3.45377211 |
5 | DAPK2 | 2.58087515 |
6 | KSR2 | 2.46543301 |
7 | MAP3K4 | 2.42246678 |
8 | MINK1 | 2.35567358 |
9 | CDK12 | 2.31448827 |
10 | PAK6 | 2.26249815 |
11 | PRKD3 | 2.23404018 |
12 | NTRK2 | 2.04427330 |
13 | CAMKK1 | 1.96789914 |
14 | TAOK1 | 1.79023704 |
15 | LATS1 | 1.74991846 |
16 | MAP2K4 | 1.69790829 |
17 | KSR1 | 1.66947139 |
18 | RIPK1 | 1.61100275 |
19 | MAP3K2 | 1.60864066 |
20 | SIK2 | 1.59890930 |
21 | TYRO3 | 1.59182623 |
22 | STK38 | 1.58293469 |
23 | NTRK1 | 1.56457932 |
24 | PHKG1 | 1.53270216 |
25 | PHKG2 | 1.53270216 |
26 | TRIB3 | 1.45591830 |
27 | DAPK1 | 1.42359059 |
28 | MAP2K7 | 1.41863070 |
29 | CDK5 | 1.41436968 |
30 | CASK | 1.41031941 |
31 | EPHA2 | 1.40436083 |
32 | LATS2 | 1.40199114 |
33 | IRAK3 | 1.40135175 |
34 | RIPK4 | 1.35355614 |
35 | SIK1 | 1.31835066 |
36 | ERN1 | 1.30365991 |
37 | ALK | 1.27037491 |
38 | LMTK2 | 1.25175443 |
39 | RET | 1.21302912 |
40 | NEK1 | 1.18466203 |
41 | NEK6 | 1.13209335 |
42 | FGFR4 | 1.12803505 |
43 | PKN2 | 1.08515096 |
44 | STK11 | 1.02645264 |
45 | PRKCH | 0.98072636 |
46 | EPHB1 | 0.96353659 |
47 | SMG1 | 0.93656104 |
48 | MAP3K13 | 0.92389598 |
49 | CAMK1G | 0.91726536 |
50 | MAP3K7 | 0.90569729 |
51 | MAP3K12 | 0.90240043 |
52 | WNK3 | 0.87431879 |
53 | MOS | 0.86719050 |
54 | STK24 | 0.86663285 |
55 | DYRK1B | 0.85861085 |
56 | MTOR | 0.85851684 |
57 | MAPK13 | 0.85459757 |
58 | ICK | 0.84561225 |
59 | MARK2 | 0.83491352 |
60 | MAPK15 | 0.83433679 |
61 | SGK3 | 0.82880354 |
62 | PTK2 | 0.82118902 |
63 | FES | 0.81867819 |
64 | UHMK1 | 0.80508391 |
65 | DMPK | 0.80460597 |
66 | PLK2 | 0.78002313 |
67 | TAOK2 | 0.77413290 |
68 | PRKCG | 0.76522450 |
69 | PDK1 | 0.75874137 |
70 | MET | 0.75572982 |
71 | FER | 0.75276799 |
72 | CAMK1 | 0.74241736 |
73 | MAP3K1 | 0.73908895 |
74 | GRK5 | 0.72761621 |
75 | IRAK2 | 0.71458703 |
76 | PDGFRA | 0.71455153 |
77 | PAK3 | 0.70880530 |
78 | BRAF | 0.70581257 |
79 | CAMKK2 | 0.70097257 |
80 | SGK1 | 0.70061438 |
81 | EEF2K | 0.69831354 |
82 | CDK15 | 0.69674319 |
83 | PDPK1 | 0.68485526 |
84 | EPHB2 | 0.68282227 |
85 | CDK18 | 0.68090022 |
86 | SCYL2 | 0.65980377 |
87 | CSNK1G2 | 0.65614136 |
88 | CDK14 | 0.63726762 |
89 | CAMK2A | 0.62485132 |
90 | PRPF4B | 0.61859549 |
91 | WNK1 | 0.61047906 |
92 | MAP3K6 | 0.60969985 |
93 | ACVR1B | 0.60897104 |
94 | CDK19 | 0.60766465 |
95 | PNCK | 0.59264633 |
96 | SGK494 | 0.57935085 |
97 | SGK223 | 0.57935085 |
98 | FGFR2 | 0.57316217 |
99 | RPS6KA2 | 0.56986577 |
100 | CDK11A | 0.56965628 |
101 | PRKCZ | 0.56566044 |
102 | RAF1 | 0.56406051 |
103 | STK38L | 0.55663300 |
104 | MST1R | 0.55637740 |
105 | FYN | 0.54424399 |
106 | MATK | 0.54255969 |
107 | SGK2 | 0.53713382 |
108 | MAP3K11 | 0.53703762 |
109 | EPHA3 | 0.53386709 |
110 | ERBB3 | 0.53000632 |
111 | FGFR3 | 0.52304758 |
112 | RPS6KA3 | 0.51961871 |
113 | MAP3K3 | 0.50684455 |
114 | DDR2 | 0.50376456 |
115 | FGR | 0.49421059 |
116 | CDC42BPA | 0.48034377 |
117 | ARAF | 0.47331797 |
118 | CAMK4 | 0.46433610 |
119 | PTK6 | 0.46401330 |
120 | BMX | 0.44488516 |
121 | DYRK1A | 0.44218792 |
122 | MELK | 0.43743778 |
123 | MAPK12 | 0.43320456 |
124 | MAP2K1 | 0.41971980 |
125 | MAP2K2 | 0.41950990 |
126 | PTK2B | 0.39900535 |
127 | MAPK10 | 0.38434662 |
128 | ERBB2 | 0.36709185 |
129 | CAMK1D | 0.34391193 |
130 | CAMK2B | 0.33666847 |
131 | FGFR1 | 0.33425388 |
132 | PDGFRB | 0.32820359 |
133 | MAP3K10 | 0.32656162 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 2.65645615 |
2 | Nicotine addiction_Homo sapiens_hsa05033 | 2.59389804 |
3 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 2.56350219 |
4 | Olfactory transduction_Homo sapiens_hsa04740 | 2.37798657 |
5 | Long-term potentiation_Homo sapiens_hsa04720 | 2.32436864 |
6 | Circadian entrainment_Homo sapiens_hsa04713 | 2.26534293 |
7 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 2.18472867 |
8 | GABAergic synapse_Homo sapiens_hsa04727 | 2.11122717 |
9 | Glutamatergic synapse_Homo sapiens_hsa04724 | 2.05204137 |
10 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 2.00714929 |
11 | Salivary secretion_Homo sapiens_hsa04970 | 1.93032636 |
12 | Amphetamine addiction_Homo sapiens_hsa05031 | 1.92467914 |
13 | Morphine addiction_Homo sapiens_hsa05032 | 1.91445302 |
14 | Gastric acid secretion_Homo sapiens_hsa04971 | 1.87724683 |
15 | Dopaminergic synapse_Homo sapiens_hsa04728 | 1.83389526 |
16 | Cholinergic synapse_Homo sapiens_hsa04725 | 1.74988232 |
17 | Insulin secretion_Homo sapiens_hsa04911 | 1.73998700 |
18 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 1.69180579 |
19 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 1.68015723 |
20 | Prion diseases_Homo sapiens_hsa05020 | 1.62931514 |
21 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 1.62092234 |
22 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 1.60968261 |
23 | Renin secretion_Homo sapiens_hsa04924 | 1.59455747 |
24 | GnRH signaling pathway_Homo sapiens_hsa04912 | 1.48722086 |
25 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.45370668 |
26 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 1.43603944 |
27 | Cocaine addiction_Homo sapiens_hsa05030 | 1.38365926 |
28 | Long-term depression_Homo sapiens_hsa04730 | 1.37615244 |
29 | Gap junction_Homo sapiens_hsa04540 | 1.33603519 |
30 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 1.33186943 |
31 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 1.32319610 |
32 | Glioma_Homo sapiens_hsa05214 | 1.31291220 |
33 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 1.30131254 |
34 | Calcium signaling pathway_Homo sapiens_hsa04020 | 1.29009976 |
35 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 1.28551660 |
36 | Notch signaling pathway_Homo sapiens_hsa04330 | 1.28332339 |
37 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 1.23087359 |
38 | Axon guidance_Homo sapiens_hsa04360 | 1.17556782 |
39 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 1.15883621 |
40 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 1.15500886 |
41 | Histidine metabolism_Homo sapiens_hsa00340 | 1.15106691 |
42 | Taste transduction_Homo sapiens_hsa04742 | 1.15004971 |
43 | cAMP signaling pathway_Homo sapiens_hsa04024 | 1.13479330 |
44 | Serotonergic synapse_Homo sapiens_hsa04726 | 1.13220095 |
45 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 1.11477859 |
46 | ErbB signaling pathway_Homo sapiens_hsa04012 | 1.11335516 |
47 | Amoebiasis_Homo sapiens_hsa05146 | 1.08363751 |
48 | Adherens junction_Homo sapiens_hsa04520 | 1.07464564 |
49 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 1.06972598 |
50 | Melanogenesis_Homo sapiens_hsa04916 | 1.05051452 |
51 | mTOR signaling pathway_Homo sapiens_hsa04150 | 1.05030964 |
52 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 1.04375000 |
53 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.98310322 |
54 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.97039778 |
55 | Endometrial cancer_Homo sapiens_hsa05213 | 0.95785473 |
56 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.95539155 |
57 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 0.91050337 |
58 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.89769613 |
59 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 0.89624361 |
60 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.88859546 |
61 | Pancreatic secretion_Homo sapiens_hsa04972 | 0.88485786 |
62 | Thyroid cancer_Homo sapiens_hsa05216 | 0.84036568 |
63 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.83812500 |
64 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.83770459 |
65 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.83290281 |
66 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.82558266 |
67 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.81133258 |
68 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 0.80746758 |
69 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 0.79987327 |
70 | PPAR signaling pathway_Homo sapiens_hsa03320 | 0.79186151 |
71 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.78905735 |
72 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.78429487 |
73 | Bile secretion_Homo sapiens_hsa04976 | 0.77919843 |
74 | Mineral absorption_Homo sapiens_hsa04978 | 0.77714568 |
75 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.77548628 |
76 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 0.77500948 |
77 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.77046904 |
78 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 0.76446622 |
79 | Bladder cancer_Homo sapiens_hsa05219 | 0.75665558 |
80 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.75330456 |
81 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 0.72866283 |
82 | Protein digestion and absorption_Homo sapiens_hsa04974 | 0.71904901 |
83 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.71852121 |
84 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 0.71576533 |
85 | Insulin signaling pathway_Homo sapiens_hsa04910 | 0.71430602 |
86 | Arginine biosynthesis_Homo sapiens_hsa00220 | 0.69901635 |
87 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.69506818 |
88 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.69328467 |
89 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.69234451 |
90 | Hepatitis C_Homo sapiens_hsa05160 | 0.67964588 |
91 | Other glycan degradation_Homo sapiens_hsa00511 | 0.67344919 |
92 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.66631076 |
93 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.66130857 |
94 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 0.65513863 |
95 | Complement and coagulation cascades_Homo sapiens_hsa04610 | 0.64919304 |
96 | Colorectal cancer_Homo sapiens_hsa05210 | 0.61430796 |
97 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.60145384 |
98 | Endocytosis_Homo sapiens_hsa04144 | 0.59914770 |
99 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 0.59092280 |
100 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.58928814 |
101 | Phototransduction_Homo sapiens_hsa04744 | 0.58490711 |
102 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 0.58019536 |
103 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 0.57996317 |
104 | TNF signaling pathway_Homo sapiens_hsa04668 | 0.56829984 |
105 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.56387958 |
106 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.54085732 |
107 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.53696960 |
108 | Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410 | 0.52194470 |
109 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.51719839 |
110 | Osteoclast differentiation_Homo sapiens_hsa04380 | 0.51463202 |
111 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.51154470 |
112 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.50351003 |
113 | Tight junction_Homo sapiens_hsa04530 | 0.49960415 |
114 | Platelet activation_Homo sapiens_hsa04611 | 0.48966498 |
115 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.48966225 |
116 | Insulin resistance_Homo sapiens_hsa04931 | 0.48647066 |
117 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.48100662 |
118 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.47109385 |
119 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.46245634 |
120 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 0.43571428 |
121 | AMPK signaling pathway_Homo sapiens_hsa04152 | 0.43402459 |
122 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 0.43211930 |
123 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 0.42705954 |
124 | Proteoglycans in cancer_Homo sapiens_hsa05205 | 0.42448634 |
125 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.41171105 |
126 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 0.40774160 |
127 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.40579615 |
128 | Circadian rhythm_Homo sapiens_hsa04710 | 0.40192591 |
129 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.40171424 |