Rank | Gene Set | Z-score |
---|---|---|
1 | axonemal dynein complex assembly (GO:0070286) | 7.87126783 |
2 | cilium movement (GO:0003341) | 6.64799713 |
3 | epithelial cilium movement (GO:0003351) | 6.26335978 |
4 | GTP biosynthetic process (GO:0006183) | 6.17565359 |
5 | cilium or flagellum-dependent cell motility (GO:0001539) | 6.00959079 |
6 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 5.74448108 |
7 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 5.43818623 |
8 | ATP synthesis coupled proton transport (GO:0015986) | 5.43818623 |
9 | axoneme assembly (GO:0035082) | 5.42431312 |
10 | epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287) | 5.40251067 |
11 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 5.36741831 |
12 | UTP biosynthetic process (GO:0006228) | 5.21158622 |
13 | motile cilium assembly (GO:0044458) | 5.14275774 |
14 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 4.88120372 |
15 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 4.88120372 |
16 | NADH dehydrogenase complex assembly (GO:0010257) | 4.88120372 |
17 | protein complex biogenesis (GO:0070271) | 4.76312013 |
18 | guanosine-containing compound biosynthetic process (GO:1901070) | 4.76082412 |
19 | respiratory electron transport chain (GO:0022904) | 4.68768539 |
20 | nucleoside diphosphate phosphorylation (GO:0006165) | 4.66167872 |
21 | UTP metabolic process (GO:0046051) | 4.64686911 |
22 | electron transport chain (GO:0022900) | 4.64577924 |
23 | CTP metabolic process (GO:0046036) | 4.63850604 |
24 | CTP biosynthetic process (GO:0006241) | 4.63850604 |
25 | axon ensheathment in central nervous system (GO:0032291) | 4.59978513 |
26 | central nervous system myelination (GO:0022010) | 4.59978513 |
27 | sequestering of actin monomers (GO:0042989) | 4.54333771 |
28 | mitochondrial respiratory chain complex assembly (GO:0033108) | 4.39635715 |
29 | regulation of cilium movement (GO:0003352) | 4.30056773 |
30 | intraciliary transport (GO:0042073) | 4.20618520 |
31 | ribosomal small subunit biogenesis (GO:0042274) | 4.15022627 |
32 | ribosomal small subunit assembly (GO:0000028) | 4.13173021 |
33 | purine ribonucleoside triphosphate biosynthetic process (GO:0009206) | 4.04183782 |
34 | pyrimidine ribonucleoside triphosphate biosynthetic process (GO:0009209) | 4.03399980 |
35 | fusion of sperm to egg plasma membrane (GO:0007342) | 4.01942996 |
36 | viral transcription (GO:0019083) | 3.98697861 |
37 | behavioral response to nicotine (GO:0035095) | 3.96883693 |
38 | purine nucleoside triphosphate biosynthetic process (GO:0009145) | 3.96655015 |
39 | protein neddylation (GO:0045116) | 3.89250733 |
40 | chaperone-mediated protein transport (GO:0072321) | 3.89040530 |
41 | cotranslational protein targeting to membrane (GO:0006613) | 3.86411905 |
42 | translational termination (GO:0006415) | 3.81628206 |
43 | protein localization to cilium (GO:0061512) | 3.79077787 |
44 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 3.77293158 |
45 | sperm motility (GO:0030317) | 3.76253252 |
46 | protein targeting to ER (GO:0045047) | 3.75521845 |
47 | mannosylation (GO:0097502) | 3.74085762 |
48 | pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148) | 3.71087804 |
49 | acrosome reaction (GO:0007340) | 3.70321633 |
50 | pyrimidine ribonucleoside triphosphate metabolic process (GO:0009208) | 3.68406112 |
51 | protein localization to endoplasmic reticulum (GO:0070972) | 3.67558769 |
52 | chromatin remodeling at centromere (GO:0031055) | 3.66926689 |
53 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 3.66418432 |
54 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 3.62907295 |
55 | respiratory chain complex IV assembly (GO:0008535) | 3.62508176 |
56 | ribonucleoside triphosphate biosynthetic process (GO:0009201) | 3.61272326 |
57 | pyrimidine nucleobase catabolic process (GO:0006208) | 3.53802399 |
58 | ventricular system development (GO:0021591) | 3.52783722 |
59 | CENP-A containing nucleosome assembly (GO:0034080) | 3.47287974 |
60 | ATP biosynthetic process (GO:0006754) | 3.43217617 |
61 | pyrimidine nucleoside triphosphate metabolic process (GO:0009147) | 3.38910186 |
62 | DNA deamination (GO:0045006) | 3.33978007 |
63 | organelle disassembly (GO:1903008) | 3.31118681 |
64 | translational elongation (GO:0006414) | 3.27044410 |
65 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 3.24917542 |
66 | termination of RNA polymerase III transcription (GO:0006386) | 3.24917542 |
67 | nonmotile primary cilium assembly (GO:0035058) | 3.22881139 |
68 | spermatid development (GO:0007286) | 3.22278662 |
69 | nucleoside triphosphate biosynthetic process (GO:0009142) | 3.21857940 |
70 | hydrogen ion transmembrane transport (GO:1902600) | 3.21447096 |
71 | cellular protein complex disassembly (GO:0043624) | 3.17798256 |
72 | protein-cofactor linkage (GO:0018065) | 3.17067142 |
73 | GPI anchor biosynthetic process (GO:0006506) | 3.16467896 |
74 | fatty acid elongation (GO:0030497) | 3.16028399 |
75 | presynaptic membrane organization (GO:0097090) | 3.15932001 |
76 | sperm-egg recognition (GO:0035036) | 3.13735469 |
77 | plasma membrane fusion (GO:0045026) | 3.12262263 |
78 | protein targeting to mitochondrion (GO:0006626) | 3.11732555 |
79 | cilium organization (GO:0044782) | 3.10183306 |
80 | establishment of integrated proviral latency (GO:0075713) | 3.08406346 |
81 | microtubule depolymerization (GO:0007019) | 3.08270997 |
82 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.07584882 |
83 | inner mitochondrial membrane organization (GO:0007007) | 3.05106513 |
84 | DNA double-strand break processing (GO:0000729) | 3.03711395 |
85 | protein K6-linked ubiquitination (GO:0085020) | 3.03101267 |
86 | resolution of meiotic recombination intermediates (GO:0000712) | 3.01998476 |
87 | deoxyribonucleoside diphosphate metabolic process (GO:0009186) | 3.01304615 |
88 | viral life cycle (GO:0019058) | 3.00674300 |
89 | DNA damage response, detection of DNA damage (GO:0042769) | 3.00412484 |
90 | cytochrome complex assembly (GO:0017004) | 2.99599671 |
91 | water-soluble vitamin biosynthetic process (GO:0042364) | 2.99267869 |
92 | binding of sperm to zona pellucida (GO:0007339) | 2.98664586 |
93 | establishment of protein localization to mitochondrion (GO:0072655) | 2.98420690 |
94 | dopamine transport (GO:0015872) | 2.97261080 |
95 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 2.96723463 |
96 | multicellular organism reproduction (GO:0032504) | 2.96223362 |
97 | cilium assembly (GO:0042384) | 2.95004516 |
98 | cullin deneddylation (GO:0010388) | 2.93521106 |
99 | male meiosis I (GO:0007141) | 2.93103761 |
100 | piRNA metabolic process (GO:0034587) | 2.92034097 |
101 | proton transport (GO:0015992) | 2.91542367 |
102 | cilium morphogenesis (GO:0060271) | 2.90817918 |
103 | ribonucleoprotein complex disassembly (GO:0032988) | 2.90555003 |
104 | presynaptic membrane assembly (GO:0097105) | 2.89110273 |
105 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 2.88783188 |
106 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 2.88783188 |
107 | proteasome assembly (GO:0043248) | 2.87419596 |
108 | positive regulation of mitochondrial fission (GO:0090141) | 2.86194237 |
109 | intracellular protein transmembrane import (GO:0044743) | 2.85375297 |
110 | translation (GO:0006412) | 2.84843673 |
111 | nucleoside diphosphate metabolic process (GO:0009132) | 2.84715394 |
112 | hydrogen transport (GO:0006818) | 2.82968434 |
113 | nucleotide phosphorylation (GO:0046939) | 2.82555420 |
114 | regulation of mitochondrial translation (GO:0070129) | 2.80741484 |
115 | platelet dense granule organization (GO:0060155) | 2.79733846 |
116 | histone exchange (GO:0043486) | 2.79214834 |
117 | nucleobase catabolic process (GO:0046113) | 2.78662718 |
118 | preassembly of GPI anchor in ER membrane (GO:0016254) | 2.78223588 |
119 | protein localization to mitochondrion (GO:0070585) | 2.77933827 |
120 | protein polyglutamylation (GO:0018095) | 2.76793956 |
121 | long-chain fatty acid biosynthetic process (GO:0042759) | 2.76553404 |
122 | neurofilament cytoskeleton organization (GO:0060052) | 2.76273572 |
123 | GPI anchor metabolic process (GO:0006505) | 2.74991100 |
124 | neuron fate determination (GO:0048664) | 2.69553166 |
125 | retinal ganglion cell axon guidance (GO:0031290) | 2.57839510 |
126 | anterograde axon cargo transport (GO:0008089) | 2.54891152 |
127 | negative regulation of synaptic transmission, glutamatergic (GO:0051967) | 2.52957215 |
128 | DNA replication-independent nucleosome organization (GO:0034724) | 2.50486975 |
129 | DNA replication-independent nucleosome assembly (GO:0006336) | 2.50486975 |
130 | kinetochore assembly (GO:0051382) | 2.49077854 |
131 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 2.48831141 |
132 | translational initiation (GO:0006413) | 2.48693943 |
133 | DNA ligation (GO:0006266) | 2.47492810 |
134 | pyrimidine deoxyribonucleotide catabolic process (GO:0009223) | 2.47420627 |
135 | ribosomal large subunit biogenesis (GO:0042273) | 2.45481785 |
136 | transmission of nerve impulse (GO:0019226) | 2.45386742 |
137 | anterograde synaptic vesicle transport (GO:0048490) | 2.44927983 |
138 | macromolecular complex disassembly (GO:0032984) | 2.43670007 |
139 | centriole replication (GO:0007099) | 2.43537117 |
140 | regulation of inhibitory postsynaptic membrane potential (GO:0060080) | 2.40953279 |
141 | microtubule polymerization or depolymerization (GO:0031109) | 2.40606286 |
142 | kinetochore organization (GO:0051383) | 2.40215128 |
143 | protein complex disassembly (GO:0043241) | 2.40090999 |
144 | mismatch repair (GO:0006298) | 2.39951639 |
Rank | Gene Set | Z-score |
---|---|---|
1 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 4.90137471 |
2 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 3.67195536 |
3 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 3.39995527 |
4 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 3.35605020 |
5 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 3.34463123 |
6 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 3.27358094 |
7 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.09099434 |
8 | EZH2_22144423_ChIP-Seq_EOC_Human | 2.91686541 |
9 | * HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.73496570 |
10 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.69595901 |
11 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 2.52477430 |
12 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 2.51550616 |
13 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.34165276 |
14 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.29502168 |
15 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 2.29218083 |
16 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.28518074 |
17 | * E2F4_17652178_ChIP-ChIP_JURKAT_Human | 2.21770015 |
18 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 2.18841421 |
19 | IGF1R_20145208_ChIP-Seq_DFB_Human | 2.18586424 |
20 | TAF15_26573619_Chip-Seq_HEK293_Human | 2.14906278 |
21 | FUS_26573619_Chip-Seq_HEK293_Human | 2.05031027 |
22 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 2.04960903 |
23 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.03757644 |
24 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 1.94867475 |
25 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.89251251 |
26 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.80295813 |
27 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.73095959 |
28 | GBX2_23144817_ChIP-Seq_PC3_Human | 1.70968743 |
29 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.70553098 |
30 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 1.68475197 |
31 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.66966168 |
32 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.66749055 |
33 | VDR_22108803_ChIP-Seq_LS180_Human | 1.65575011 |
34 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.59470068 |
35 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.57110281 |
36 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.55966469 |
37 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.51912077 |
38 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.50947768 |
39 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.50721281 |
40 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.50691629 |
41 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.46922815 |
42 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.46084221 |
43 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.40536619 |
44 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.39734829 |
45 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 1.35835141 |
46 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.33310408 |
47 | E2F7_22180533_ChIP-Seq_HELA_Human | 1.33160517 |
48 | SIN3B_21632747_ChIP-Seq_MESCs_Mouse | 1.33085831 |
49 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.32855562 |
50 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.32371562 |
51 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.31531790 |
52 | RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse | 1.31093439 |
53 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.29936431 |
54 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.29763195 |
55 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.29019486 |
56 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 1.28228895 |
57 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 1.27424888 |
58 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.26571440 |
59 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.25842467 |
60 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.25466156 |
61 | SOX2_16153702_ChIP-ChIP_HESCs_Human | 1.20841161 |
62 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.20763318 |
63 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.20691440 |
64 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.19312103 |
65 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 1.17962345 |
66 | TAL1_26923725_Chip-Seq_HPCs_Mouse | 1.17509392 |
67 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.16883996 |
68 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 1.16428575 |
69 | ERG_20887958_ChIP-Seq_HPC-7_Mouse | 1.16343250 |
70 | P300_19829295_ChIP-Seq_ESCs_Human | 1.15073370 |
71 | * GABP_19822575_ChIP-Seq_HepG2_Human | 1.12881999 |
72 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 1.12378779 |
73 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.11895801 |
74 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 1.11232793 |
75 | EWS_26573619_Chip-Seq_HEK293_Human | 1.11110376 |
76 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.10525127 |
77 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.10419039 |
78 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.09037121 |
79 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 1.08892380 |
80 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.05625676 |
81 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.04250870 |
82 | REST_18959480_ChIP-ChIP_MESCs_Mouse | 1.03611022 |
83 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.02988901 |
84 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.02700536 |
85 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.02636751 |
86 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.02636751 |
87 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.02398889 |
88 | AR_25329375_ChIP-Seq_VCAP_Human | 1.02196046 |
89 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 0.99015341 |
90 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 0.98923451 |
91 | DMRT1_21621532_ChIP-ChIP_FETAL_Ovary | 0.98886828 |
92 | * E2F1_18555785_ChIP-Seq_MESCs_Mouse | 0.97606466 |
93 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 0.97509209 |
94 | SMAD4_21799915_ChIP-Seq_A2780_Human | 0.94987728 |
95 | EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse | 0.94947648 |
96 | ERG_20517297_ChIP-Seq_VCAP_Human | 0.94652897 |
97 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 0.94633210 |
98 | SIN3A_21632747_ChIP-Seq_MESCs_Mouse | 0.94361796 |
99 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.94027290 |
100 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 0.94027290 |
101 | NANOG_18555785_Chip-Seq_ESCs_Mouse | 0.93730918 |
102 | HTT_18923047_ChIP-ChIP_STHdh_Human | 0.93664707 |
103 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 0.93339338 |
104 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 0.92814515 |
105 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 0.92814515 |
106 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 0.92552807 |
107 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 0.92384609 |
108 | P53_22387025_ChIP-Seq_ESCs_Mouse | 0.91949139 |
109 | SUZ12_18555785_Chip-Seq_ESCs_Mouse | 0.91741766 |
110 | STAT3_18555785_Chip-Seq_ESCs_Mouse | 0.91328549 |
111 | SOX2_19829295_ChIP-Seq_ESCs_Human | 0.91277542 |
112 | NANOG_19829295_ChIP-Seq_ESCs_Human | 0.91277542 |
113 | EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 0.91086783 |
114 | MYC_18940864_ChIP-ChIP_HL60_Human | 0.90659738 |
115 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 0.89985123 |
116 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 0.89284942 |
117 | SCL_19346495_ChIP-Seq_HPC-7_Human | 0.89020551 |
118 | * NCOR_22424771_ChIP-Seq_293T_Human | 0.89013583 |
119 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 0.88645046 |
120 | EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse | 0.88511466 |
121 | P300_18555785_Chip-Seq_ESCs_Mouse | 0.88353580 |
122 | SOX2_18555785_ChIP-Seq_MESCs_Mouse | 0.88335250 |
123 | SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 0.88127714 |
124 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 0.87630100 |
125 | CTCF_18555785_ChIP-Seq_MESCs_Mouse | 0.87170774 |
126 | ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 0.86355887 |
127 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 0.86310760 |
128 | * FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse | 0.86235452 |
129 | REST_21632747_ChIP-Seq_MESCs_Mouse | 0.85541826 |
130 | NANOG_20526341_ChIP-Seq_ESCs_Human | 0.85534965 |
131 | TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 0.84520079 |
132 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 0.82570725 |
133 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 0.81499859 |
134 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 0.80408844 |
135 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 0.79785264 |
136 | GATA1_26923725_Chip-Seq_HPCs_Mouse | 0.79648156 |
137 | RUNX1_27457419_Chip-Seq_LIVER_Mouse | 0.79364441 |
138 | CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse | 0.79085696 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0005410_abnormal_fertilization | 4.55847454 |
2 | MP0003136_yellow_coat_color | 4.44085371 |
3 | MP0009379_abnormal_foot_pigmentation | 3.72497897 |
4 | MP0003880_abnormal_central_pattern | 3.59354726 |
5 | MP0001529_abnormal_vocalization | 2.78675839 |
6 | MP0001905_abnormal_dopamine_level | 2.63761191 |
7 | MP0001188_hyperpigmentation | 2.47697881 |
8 | MP0001986_abnormal_taste_sensitivity | 2.31864404 |
9 | MP0002102_abnormal_ear_morphology | 2.26098381 |
10 | MP0005409_darkened_coat_color | 2.25503725 |
11 | MP0006292_abnormal_olfactory_placode | 2.21284337 |
12 | MP0005075_abnormal_melanosome_morpholog | 2.04655017 |
13 | MP0004147_increased_porphyrin_level | 2.03513895 |
14 | MP0003122_maternal_imprinting | 2.03348462 |
15 | MP0003698_abnormal_male_reproductive | 2.01654803 |
16 | MP0003121_genomic_imprinting | 1.98803552 |
17 | MP0001984_abnormal_olfaction | 1.97195117 |
18 | MP0004142_abnormal_muscle_tone | 1.90827209 |
19 | MP0002272_abnormal_nervous_system | 1.89976214 |
20 | MP0002736_abnormal_nociception_after | 1.87366727 |
21 | MP0001929_abnormal_gametogenesis | 1.87225639 |
22 | MP0009046_muscle_twitch | 1.86074070 |
23 | MP0005499_abnormal_olfactory_system | 1.85535590 |
24 | MP0005394_taste/olfaction_phenotype | 1.85535590 |
25 | MP0001968_abnormal_touch/_nociception | 1.83585535 |
26 | MP0003787_abnormal_imprinting | 1.80855597 |
27 | MP0005084_abnormal_gallbladder_morpholo | 1.80429813 |
28 | MP0006036_abnormal_mitochondrial_physio | 1.79690432 |
29 | MP0002638_abnormal_pupillary_reflex | 1.74990862 |
30 | MP0006276_abnormal_autonomic_nervous | 1.68805121 |
31 | MP0002938_white_spotting | 1.68416780 |
32 | MP0002234_abnormal_pharynx_morphology | 1.67589030 |
33 | MP0004270_analgesia | 1.66456139 |
34 | MP0000920_abnormal_myelination | 1.61060211 |
35 | MP0008877_abnormal_DNA_methylation | 1.57639657 |
36 | MP0009745_abnormal_behavioral_response | 1.57604827 |
37 | MP0008995_early_reproductive_senescence | 1.57321577 |
38 | MP0002837_dystrophic_cardiac_calcinosis | 1.53226547 |
39 | MP0002095_abnormal_skin_pigmentation | 1.52737314 |
40 | MP0002734_abnormal_mechanical_nocicepti | 1.50869822 |
41 | MP0002064_seizures | 1.50148657 |
42 | MP0004885_abnormal_endolymph | 1.49776796 |
43 | MP0000372_irregular_coat_pigmentation | 1.49543241 |
44 | MP0001293_anophthalmia | 1.49096883 |
45 | MP0004381_abnormal_hair_follicle | 1.48312173 |
46 | MP0001486_abnormal_startle_reflex | 1.44844062 |
47 | MP0005646_abnormal_pituitary_gland | 1.41011296 |
48 | MP0002160_abnormal_reproductive_system | 1.36191811 |
49 | MP0001440_abnormal_grooming_behavior | 1.35102392 |
50 | MP0002210_abnormal_sex_determination | 1.33657425 |
51 | MP0002572_abnormal_emotion/affect_behav | 1.32339021 |
52 | MP0003011_delayed_dark_adaptation | 1.31926885 |
53 | MP0003635_abnormal_synaptic_transmissio | 1.31913622 |
54 | MP0001485_abnormal_pinna_reflex | 1.28048527 |
55 | MP0003123_paternal_imprinting | 1.27876234 |
56 | MP0009697_abnormal_copulation | 1.27415923 |
57 | MP0003718_maternal_effect | 1.25256251 |
58 | MP0004742_abnormal_vestibular_system | 1.24576791 |
59 | MP0002735_abnormal_chemical_nociception | 1.22575118 |
60 | MP0005423_abnormal_somatic_nervous | 1.22026850 |
61 | MP0002067_abnormal_sensory_capabilities | 1.21478106 |
62 | MP0005645_abnormal_hypothalamus_physiol | 1.20429064 |
63 | MP0010094_abnormal_chromosome_stability | 1.19861735 |
64 | MP0006072_abnormal_retinal_apoptosis | 1.19722709 |
65 | MP0001970_abnormal_pain_threshold | 1.19198928 |
66 | MP0004145_abnormal_muscle_electrophysio | 1.19126445 |
67 | MP0005379_endocrine/exocrine_gland_phen | 1.18178393 |
68 | MP0006035_abnormal_mitochondrial_morpho | 1.18123636 |
69 | MP0002928_abnormal_bile_duct | 1.16458254 |
70 | MP0000749_muscle_degeneration | 1.16091553 |
71 | MP0005171_absent_coat_pigmentation | 1.14571647 |
72 | MP0010386_abnormal_urinary_bladder | 1.14495397 |
73 | MP0005551_abnormal_eye_electrophysiolog | 1.12704724 |
74 | MP0003656_abnormal_erythrocyte_physiolo | 1.09810275 |
75 | MP0002229_neurodegeneration | 1.09093128 |
76 | MP0005174_abnormal_tail_pigmentation | 1.07594585 |
77 | MP0000015_abnormal_ear_pigmentation | 1.06282832 |
78 | MP0001145_abnormal_male_reproductive | 1.03765557 |
79 | MP0008057_abnormal_DNA_replication | 1.02802666 |
80 | MP0002233_abnormal_nose_morphology | 1.02275902 |
81 | MP0008569_lethality_at_weaning | 1.01670859 |
82 | MP0003890_abnormal_embryonic-extraembry | 1.00917575 |
83 | MP0008875_abnormal_xenobiotic_pharmacok | 1.00609916 |
84 | MP0008058_abnormal_DNA_repair | 0.99616052 |
85 | MP0003693_abnormal_embryo_hatching | 0.97898265 |
86 | MP0000631_abnormal_neuroendocrine_gland | 0.97652576 |
87 | MP0003186_abnormal_redox_activity | 0.97039341 |
88 | MP0003950_abnormal_plasma_membrane | 0.97033573 |
89 | MP0002653_abnormal_ependyma_morphology | 0.96729991 |
90 | MP0000026_abnormal_inner_ear | 0.96067510 |
91 | MP0000566_synostosis | 0.96007993 |
92 | MP0003646_muscle_fatigue | 0.95852395 |
93 | MP0001664_abnormal_digestion | 0.95645141 |
94 | MP0001963_abnormal_hearing_physiology | 0.95146706 |
95 | MP0002161_abnormal_fertility/fecundity | 0.94901114 |
96 | MP0000653_abnormal_sex_gland | 0.94597504 |
97 | MP0005389_reproductive_system_phenotype | 0.94324795 |
98 | MP0002733_abnormal_thermal_nociception | 0.94114540 |
99 | MP0005195_abnormal_posterior_eye | 0.93863609 |
100 | MP0005187_abnormal_penis_morphology | 0.92850930 |
101 | MP0001764_abnormal_homeostasis | 0.91112251 |
102 | MP0000049_abnormal_middle_ear | 0.91111437 |
103 | MP0000569_abnormal_digit_pigmentation | 0.90900647 |
104 | MP0002063_abnormal_learning/memory/cond | 0.89487724 |
105 | MP0003937_abnormal_limbs/digits/tail_de | 0.88620583 |
106 | MP0004811_abnormal_neuron_physiology | 0.88591488 |
107 | MP0002557_abnormal_social/conspecific_i | 0.88520324 |
108 | MP0001286_abnormal_eye_development | 0.86601450 |
109 | MP0003119_abnormal_digestive_system | 0.85698858 |
110 | MP0008932_abnormal_embryonic_tissue | 0.85428813 |
111 | MP0002752_abnormal_somatic_nervous | 0.83465678 |
112 | MP0005386_behavior/neurological_phenoty | 0.83463306 |
113 | MP0004924_abnormal_behavior | 0.83463306 |
114 | MP0005253_abnormal_eye_physiology | 0.82811302 |
115 | MP0004859_abnormal_synaptic_plasticity | 0.81837344 |
116 | MP0002876_abnormal_thyroid_physiology | 0.80416485 |
117 | MP0004133_heterotaxia | 0.79582783 |
118 | MP0008872_abnormal_physiological_respon | 0.78820910 |
119 | MP0003879_abnormal_hair_cell | 0.77956593 |
120 | MP0002163_abnormal_gland_morphology | 0.77058594 |
121 | MP0001501_abnormal_sleep_pattern | 0.76166610 |
122 | MP0003786_premature_aging | 0.75511247 |
123 | MP0002882_abnormal_neuron_morphology | 0.75409189 |
124 | MP0002132_abnormal_respiratory_system | 0.75186505 |
125 | MP0002751_abnormal_autonomic_nervous | 0.74881064 |
126 | MP0000778_abnormal_nervous_system | 0.74808683 |
127 | MP0002066_abnormal_motor_capabilities/c | 0.71189182 |
128 | MP0002184_abnormal_innervation | 0.70449209 |
129 | MP0002822_catalepsy | 0.70291589 |
130 | MP0000955_abnormal_spinal_cord | 0.69490462 |
131 | MP0005636_abnormal_mineral_homeostasis | 0.69091784 |
132 | MP0003634_abnormal_glial_cell | 0.68988550 |
133 | MP0008004_abnormal_stomach_pH | 0.68974424 |
134 | MP0008789_abnormal_olfactory_epithelium | 0.67196347 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Respiratory insufficiency due to defective ciliary clearance (HP:0200073) | 7.97432839 |
2 | Abnormal respiratory motile cilium physiology (HP:0012261) | 7.13495090 |
3 | Abnormal ciliary motility (HP:0012262) | 6.74630016 |
4 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 6.18592655 |
5 | Absent/shortened dynein arms (HP:0200106) | 6.18592655 |
6 | Abnormal respiratory motile cilium morphology (HP:0005938) | 5.92511938 |
7 | Abnormal respiratory epithelium morphology (HP:0012253) | 5.92511938 |
8 | Rhinitis (HP:0012384) | 5.65195184 |
9 | Acute necrotizing encephalopathy (HP:0006965) | 4.82026878 |
10 | Abnormal mitochondria in muscle tissue (HP:0008316) | 4.35324029 |
11 | Mitochondrial inheritance (HP:0001427) | 4.24893308 |
12 | Chronic bronchitis (HP:0004469) | 4.22715692 |
13 | Progressive macrocephaly (HP:0004481) | 4.00577627 |
14 | Acute encephalopathy (HP:0006846) | 3.71626301 |
15 | Hepatocellular necrosis (HP:0001404) | 3.56998012 |
16 | Increased CSF lactate (HP:0002490) | 3.54816636 |
17 | Renal Fanconi syndrome (HP:0001994) | 3.48587419 |
18 | Increased hepatocellular lipid droplets (HP:0006565) | 3.47664739 |
19 | 3-Methylglutaconic aciduria (HP:0003535) | 3.42559002 |
20 | True hermaphroditism (HP:0010459) | 3.41340372 |
21 | Medial flaring of the eyebrow (HP:0010747) | 3.39504609 |
22 | Abnormality of cells of the erythroid lineage (HP:0012130) | 3.34204140 |
23 | Bronchiectasis (HP:0002110) | 3.33458665 |
24 | Pancreatic fibrosis (HP:0100732) | 3.28871085 |
25 | Abnormal number of erythroid precursors (HP:0012131) | 3.20012964 |
26 | Lipid accumulation in hepatocytes (HP:0006561) | 3.05567357 |
27 | Hepatic necrosis (HP:0002605) | 2.98493997 |
28 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 2.93058375 |
29 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 2.93058375 |
30 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.91472336 |
31 | Pancreatic cysts (HP:0001737) | 2.84304284 |
32 | Abnormality of the labia minora (HP:0012880) | 2.77225335 |
33 | Abnormality of midbrain morphology (HP:0002418) | 2.75087880 |
34 | Molar tooth sign on MRI (HP:0002419) | 2.75087880 |
35 | Congenital primary aphakia (HP:0007707) | 2.74893190 |
36 | Nasal polyposis (HP:0100582) | 2.73981583 |
37 | Optic disc pallor (HP:0000543) | 2.73808021 |
38 | Retinal dysplasia (HP:0007973) | 2.72933150 |
39 | Gait imbalance (HP:0002141) | 2.72729570 |
40 | Exercise intolerance (HP:0003546) | 2.72718770 |
41 | Infertility (HP:0000789) | 2.70763194 |
42 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 2.70043130 |
43 | Increased intramyocellular lipid droplets (HP:0012240) | 2.64606174 |
44 | Leukodystrophy (HP:0002415) | 2.61356722 |
45 | Abnormality of renal resorption (HP:0011038) | 2.60580988 |
46 | Nephrogenic diabetes insipidus (HP:0009806) | 2.59497055 |
47 | Nephronophthisis (HP:0000090) | 2.58695684 |
48 | Abnormality of the heme biosynthetic pathway (HP:0010472) | 2.48656898 |
49 | Lactic acidosis (HP:0003128) | 2.42818136 |
50 | Reticulocytopenia (HP:0001896) | 2.42309583 |
51 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 2.42009647 |
52 | Tubulointerstitial nephritis (HP:0001970) | 2.41991192 |
53 | Bronchitis (HP:0012387) | 2.36919776 |
54 | Abnormality of glycolysis (HP:0004366) | 2.35656510 |
55 | Increased serum pyruvate (HP:0003542) | 2.35656510 |
56 | Respiratory failure (HP:0002878) | 2.30304717 |
57 | Cerebral edema (HP:0002181) | 2.27980117 |
58 | Increased serum lactate (HP:0002151) | 2.27890412 |
59 | Myokymia (HP:0002411) | 2.27645549 |
60 | Exertional dyspnea (HP:0002875) | 2.27302398 |
61 | Hypothermia (HP:0002045) | 2.25147155 |
62 | Meckel diverticulum (HP:0002245) | 2.24875321 |
63 | Renal cortical cysts (HP:0000803) | 2.22800713 |
64 | Methylmalonic acidemia (HP:0002912) | 2.20385674 |
65 | Abnormality of the renal cortex (HP:0011035) | 2.20264625 |
66 | Congenital stationary night blindness (HP:0007642) | 2.19541021 |
67 | Genital tract atresia (HP:0001827) | 2.18610332 |
68 | Abnormality of the ileum (HP:0001549) | 2.18493471 |
69 | Increased muscle lipid content (HP:0009058) | 2.16942792 |
70 | Vaginal atresia (HP:0000148) | 2.16728864 |
71 | Recurrent sinusitis (HP:0011108) | 2.15946068 |
72 | Microvesicular hepatic steatosis (HP:0001414) | 2.13643407 |
73 | Occipital encephalocele (HP:0002085) | 2.12395399 |
74 | Respiratory difficulties (HP:0002880) | 2.08063094 |
75 | Abnormality of the nasal mucosa (HP:0000433) | 2.08035261 |
76 | Poor suck (HP:0002033) | 2.07091236 |
77 | Supernumerary spleens (HP:0009799) | 2.07005915 |
78 | Neuroendocrine neoplasm (HP:0100634) | 2.06237695 |
79 | Colon cancer (HP:0003003) | 2.04475031 |
80 | Sclerocornea (HP:0000647) | 2.02294865 |
81 | Aplastic anemia (HP:0001915) | 2.00826899 |
82 | Polyphagia (HP:0002591) | 1.98018255 |
83 | Type I transferrin isoform profile (HP:0003642) | 1.94299369 |
84 | Abnormality of urine glucose concentration (HP:0011016) | 1.93869744 |
85 | Glycosuria (HP:0003076) | 1.93869744 |
86 | Pendular nystagmus (HP:0012043) | 1.93739776 |
87 | Triphalangeal thumb (HP:0001199) | 1.92766665 |
88 | Chronic sinusitis (HP:0011109) | 1.92444421 |
89 | Parakeratosis (HP:0001036) | 1.91703249 |
90 | Postaxial foot polydactyly (HP:0001830) | 1.90994565 |
91 | Congenital, generalized hypertrichosis (HP:0004540) | 1.89515268 |
92 | 11 pairs of ribs (HP:0000878) | 1.89309305 |
93 | Lissencephaly (HP:0001339) | 1.87339612 |
94 | Congenital nonbullous ichthyosiform erythroderma (HP:0007479) | 1.87130299 |
95 | Anencephaly (HP:0002323) | 1.86866876 |
96 | Anophthalmia (HP:0000528) | 1.86801777 |
97 | Postaxial hand polydactyly (HP:0001162) | 1.85175892 |
98 | Degeneration of the lateral corticospinal tracts (HP:0002314) | 1.85099822 |
99 | Atrophy/Degeneration involving the corticospinal tracts (HP:0007372) | 1.85099822 |
100 | Absent thumb (HP:0009777) | 1.85061461 |
101 | Abnormality of the renal medulla (HP:0100957) | 1.84931573 |
102 | Aplasia/Hypoplasia of the lens (HP:0008063) | 1.84869210 |
103 | Cerebral hypomyelination (HP:0006808) | 1.84579263 |
104 | Poor coordination (HP:0002370) | 1.84441049 |
105 | Congenital hepatic fibrosis (HP:0002612) | 1.83755494 |
106 | Septo-optic dysplasia (HP:0100842) | 1.83655975 |
107 | Abnormality of the preputium (HP:0100587) | 1.82620258 |
108 | Preaxial hand polydactyly (HP:0001177) | 1.82589921 |
109 | Concave nail (HP:0001598) | 1.81966329 |
110 | Asplenia (HP:0001746) | 1.81942673 |
111 | Fibular hypoplasia (HP:0003038) | 1.81357775 |
112 | Pheochromocytoma (HP:0002666) | 1.79530602 |
113 | Hyperglycinemia (HP:0002154) | 1.77529715 |
114 | Recurrent otitis media (HP:0000403) | 1.76907781 |
115 | Macrocytic anemia (HP:0001972) | 1.76598809 |
116 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 1.75355609 |
117 | Abnormality of alanine metabolism (HP:0010916) | 1.75355609 |
118 | Hyperalaninemia (HP:0003348) | 1.75355609 |
119 | Chronic hepatic failure (HP:0100626) | 1.73871441 |
120 | Aganglionic megacolon (HP:0002251) | 1.72229098 |
121 | Limb dystonia (HP:0002451) | 1.70581349 |
122 | Small intestinal stenosis (HP:0012848) | 1.70548617 |
123 | Duodenal stenosis (HP:0100867) | 1.70548617 |
124 | Abnormality of chromosome stability (HP:0003220) | 1.70218174 |
125 | Type II lissencephaly (HP:0007260) | 1.69093231 |
126 | Male pseudohermaphroditism (HP:0000037) | 1.67094775 |
127 | Nonprogressive disorder (HP:0003680) | 1.65803585 |
128 | Aplasia/Hypoplasia of the tongue (HP:0010295) | 1.65628584 |
129 | Cystic liver disease (HP:0006706) | 1.64824610 |
130 | Focal motor seizures (HP:0011153) | 1.63222091 |
131 | Abnormal biliary tract physiology (HP:0012439) | 1.60691570 |
132 | Bile duct proliferation (HP:0001408) | 1.60691570 |
133 | Patchy hypopigmentation of hair (HP:0011365) | 1.56680099 |
134 | Epileptic encephalopathy (HP:0200134) | 1.56125266 |
135 | X-linked dominant inheritance (HP:0001423) | 1.56006835 |
Rank | Gene Set | Z-score |
---|---|---|
1 | PNCK | 3.75469213 |
2 | STK16 | 3.42358578 |
3 | CDK19 | 3.20763104 |
4 | VRK2 | 3.03502866 |
5 | STK39 | 2.72783827 |
6 | MAPK15 | 2.72326714 |
7 | MST4 | 2.61693032 |
8 | TNIK | 2.55154252 |
9 | CASK | 2.51693819 |
10 | MAP3K12 | 2.51493326 |
11 | MAP4K2 | 2.51038317 |
12 | PDK3 | 2.48821625 |
13 | PDK4 | 2.48821625 |
14 | MUSK | 2.39536153 |
15 | ARAF | 2.22403982 |
16 | VRK1 | 2.21814681 |
17 | NME1 | 2.18670919 |
18 | MARK1 | 2.16894994 |
19 | NUAK1 | 2.14614106 |
20 | OXSR1 | 2.09488396 |
21 | CDC7 | 2.09038180 |
22 | MAP2K7 | 1.98247227 |
23 | MAPKAPK5 | 1.88825382 |
24 | NME2 | 1.88423639 |
25 | PLK4 | 1.85825197 |
26 | INSRR | 1.81083726 |
27 | PIM2 | 1.67248885 |
28 | WEE1 | 1.62057251 |
29 | MYLK | 1.61376632 |
30 | FRK | 1.59906785 |
31 | BUB1 | 1.59776990 |
32 | TRIM28 | 1.38526178 |
33 | WNK4 | 1.37937284 |
34 | PLK3 | 1.34418124 |
35 | CSNK1G3 | 1.31264470 |
36 | BCKDK | 1.23982810 |
37 | MINK1 | 1.23336187 |
38 | CCNB1 | 1.21966768 |
39 | PDK2 | 1.19979470 |
40 | GRK5 | 1.13947031 |
41 | GRK7 | 1.13481190 |
42 | NEK1 | 1.12233326 |
43 | BRSK2 | 1.10162092 |
44 | ADRBK2 | 1.05980070 |
45 | SRPK1 | 1.04686390 |
46 | PLK1 | 1.03598603 |
47 | BMPR1B | 1.01675339 |
48 | DYRK3 | 1.00321011 |
49 | TAF1 | 0.97545329 |
50 | TESK1 | 0.96976560 |
51 | EPHA4 | 0.95724581 |
52 | PASK | 0.95290018 |
53 | PTK2B | 0.93222016 |
54 | BRAF | 0.92853786 |
55 | ERBB3 | 0.91880642 |
56 | MKNK2 | 0.87843187 |
57 | NTRK2 | 0.87608833 |
58 | MAPK13 | 0.87089652 |
59 | EIF2AK3 | 0.86065750 |
60 | CSNK1G1 | 0.85818845 |
61 | CDK8 | 0.85454540 |
62 | MKNK1 | 0.85187931 |
63 | BCR | 0.83395216 |
64 | CSNK1A1L | 0.81863063 |
65 | CAMK2B | 0.81616148 |
66 | CSNK1G2 | 0.80030628 |
67 | LIMK1 | 0.79771840 |
68 | RPS6KA5 | 0.78738763 |
69 | TEC | 0.77403043 |
70 | TTK | 0.74002141 |
71 | PAK3 | 0.73561467 |
72 | TXK | 0.73018412 |
73 | NEK6 | 0.71278977 |
74 | MAP3K4 | 0.70316914 |
75 | DYRK1A | 0.69891611 |
76 | EIF2AK1 | 0.69274573 |
77 | CDK3 | 0.68938721 |
78 | RPS6KA4 | 0.68865256 |
79 | NTRK3 | 0.68029633 |
80 | PLK2 | 0.67162629 |
81 | PINK1 | 0.65098703 |
82 | BMPR2 | 0.64586529 |
83 | CHEK2 | 0.63662418 |
84 | AURKB | 0.63425355 |
85 | DYRK2 | 0.62686046 |
86 | PRKCE | 0.62144664 |
87 | ATR | 0.61765479 |
88 | CAMK2A | 0.59073722 |
89 | CAMK1 | 0.58809086 |
90 | UHMK1 | 0.58615893 |
91 | EIF2AK2 | 0.57540173 |
92 | CAMK2G | 0.56566287 |
93 | OBSCN | 0.56493748 |
94 | PIK3CG | 0.56358011 |
95 | BRSK1 | 0.56035819 |
96 | MAP2K6 | 0.55801155 |
97 | TAOK3 | 0.55655926 |
98 | CAMKK2 | 0.54584829 |
99 | TLK1 | 0.53783709 |
100 | RIPK4 | 0.53606986 |
101 | CAMK2D | 0.52704952 |
102 | MAP2K4 | 0.52154814 |
103 | WNK1 | 0.51878911 |
104 | YES1 | 0.51446693 |
105 | GRK1 | 0.50756680 |
106 | PHKG2 | 0.50718652 |
107 | PHKG1 | 0.50718652 |
108 | TNK2 | 0.50136797 |
109 | AURKA | 0.49231693 |
110 | RAF1 | 0.49060133 |
111 | FES | 0.48565873 |
112 | ZAK | 0.48113464 |
113 | CLK1 | 0.47953752 |
114 | PRKCG | 0.47250160 |
115 | DAPK1 | 0.46581588 |
116 | CSNK1E | 0.46359044 |
117 | TESK2 | 0.45674417 |
118 | DAPK2 | 0.45416970 |
119 | NEK2 | 0.45375490 |
120 | IRAK1 | 0.43987269 |
121 | CSNK1A1 | 0.43556556 |
122 | MAPK4 | 0.43141569 |
123 | PKN1 | 0.42487848 |
124 | CSNK2A2 | 0.42407563 |
125 | PIK3CA | 0.41544286 |
126 | PRKACB | 0.40938738 |
127 | ADRBK1 | 0.40357005 |
128 | CSNK2A1 | 0.39955875 |
129 | ROCK2 | 0.39889184 |
130 | WNK3 | 0.39808928 |
131 | TSSK6 | 0.39157606 |
132 | CSNK1D | 0.39144228 |
133 | SYK | 0.37291125 |
134 | PRKACA | 0.37193683 |
135 | KIT | 0.36774598 |
136 | PBK | 0.36534196 |
137 | CDK11A | 0.36278071 |
138 | MAP3K6 | 0.35880693 |
139 | CDK14 | 0.34965432 |
140 | CDK18 | 0.34552513 |
141 | ACVR1B | 0.32020816 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 5.10190272 |
2 | Parkinsons disease_Homo sapiens_hsa05012 | 4.36686513 |
3 | Ribosome_Homo sapiens_hsa03010 | 4.32237495 |
4 | Protein export_Homo sapiens_hsa03060 | 3.66013123 |
5 | Huntingtons disease_Homo sapiens_hsa05016 | 3.56143991 |
6 | Alzheimers disease_Homo sapiens_hsa05010 | 3.33667282 |
7 | Proteasome_Homo sapiens_hsa03050 | 3.02894908 |
8 | RNA polymerase_Homo sapiens_hsa03020 | 2.66948099 |
9 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 2.49810975 |
10 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 2.20462464 |
11 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.95055298 |
12 | Fatty acid elongation_Homo sapiens_hsa00062 | 1.90176698 |
13 | Sulfur metabolism_Homo sapiens_hsa00920 | 1.81013387 |
14 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.78141455 |
15 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 1.77700711 |
16 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 1.66987482 |
17 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.62351633 |
18 | Basal transcription factors_Homo sapiens_hsa03022 | 1.61112863 |
19 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.59046310 |
20 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.56299500 |
21 | Purine metabolism_Homo sapiens_hsa00230 | 1.47910250 |
22 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.43133517 |
23 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.39240671 |
24 | Homologous recombination_Homo sapiens_hsa03440 | 1.38045235 |
25 | DNA replication_Homo sapiens_hsa03030 | 1.24818184 |
26 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 1.20082082 |
27 | Ether lipid metabolism_Homo sapiens_hsa00565 | 1.19548892 |
28 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 1.16253274 |
29 | Nicotine addiction_Homo sapiens_hsa05033 | 1.16177604 |
30 | Spliceosome_Homo sapiens_hsa03040 | 1.15612992 |
31 | Mismatch repair_Homo sapiens_hsa03430 | 1.12060569 |
32 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.11729216 |
33 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 1.09867374 |
34 | Phototransduction_Homo sapiens_hsa04744 | 1.07330861 |
35 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 1.04351848 |
36 | RNA degradation_Homo sapiens_hsa03018 | 1.03713130 |
37 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.99319356 |
38 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.97976313 |
39 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.95961512 |
40 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.94369036 |
41 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.94352200 |
42 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.91571112 |
43 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 0.88494761 |
44 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.87327326 |
45 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.87256522 |
46 | Amphetamine addiction_Homo sapiens_hsa05031 | 0.87161571 |
47 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 0.86990917 |
48 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.86895167 |
49 | * Pyruvate metabolism_Homo sapiens_hsa00620 | 0.85253579 |
50 | Metabolic pathways_Homo sapiens_hsa01100 | 0.85174363 |
51 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.84943961 |
52 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.82650396 |
53 | Taste transduction_Homo sapiens_hsa04742 | 0.80906237 |
54 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 0.80206666 |
55 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.76039583 |
56 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.73355670 |
57 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 0.72798200 |
58 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 0.71515823 |
59 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.68520920 |
60 | Morphine addiction_Homo sapiens_hsa05032 | 0.66686247 |
61 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.66088497 |
62 | Alcoholism_Homo sapiens_hsa05034 | 0.64555620 |
63 | Circadian entrainment_Homo sapiens_hsa04713 | 0.63252851 |
64 | Olfactory transduction_Homo sapiens_hsa04740 | 0.62627864 |
65 | Base excision repair_Homo sapiens_hsa03410 | 0.61727220 |
66 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.60008156 |
67 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.59238821 |
68 | GABAergic synapse_Homo sapiens_hsa04727 | 0.58165421 |
69 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.58135814 |
70 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.56911645 |
71 | Glutamatergic synapse_Homo sapiens_hsa04724 | 0.56845163 |
72 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.56832664 |
73 | Dopaminergic synapse_Homo sapiens_hsa04728 | 0.56569611 |
74 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.54537126 |
75 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.51335016 |
76 | Asthma_Homo sapiens_hsa05310 | 0.50859485 |
77 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.50242295 |
78 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.49929748 |
79 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.49846470 |
80 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.49767888 |
81 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.49560035 |
82 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.47981903 |
83 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.47566799 |
84 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.47210819 |
85 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.47046864 |
86 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.46871302 |
87 | Calcium signaling pathway_Homo sapiens_hsa04020 | 0.46662242 |
88 | Cocaine addiction_Homo sapiens_hsa05030 | 0.45759425 |
89 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.45030807 |
90 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.43425233 |
91 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.43145983 |
92 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.42421308 |
93 | Renin secretion_Homo sapiens_hsa04924 | 0.40454393 |
94 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.40371848 |
95 | RNA transport_Homo sapiens_hsa03013 | 0.37815151 |
96 | Long-term depression_Homo sapiens_hsa04730 | 0.37099796 |
97 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.37092319 |
98 | Sulfur relay system_Homo sapiens_hsa04122 | 0.36468145 |
99 | Long-term potentiation_Homo sapiens_hsa04720 | 0.36056889 |
100 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.35685734 |
101 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.35154129 |
102 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.34011496 |
103 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.33442848 |
104 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.31377477 |
105 | Salivary secretion_Homo sapiens_hsa04970 | 0.31084064 |
106 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.30238956 |
107 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.29668031 |
108 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.27723510 |
109 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.27239452 |
110 | Phagosome_Homo sapiens_hsa04145 | 0.26871699 |
111 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.26853700 |
112 | Retinol metabolism_Homo sapiens_hsa00830 | 0.24999905 |
113 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.24991733 |
114 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.24867003 |
115 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.24787114 |
116 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.21867550 |
117 | Histidine metabolism_Homo sapiens_hsa00340 | 0.21703998 |
118 | Axon guidance_Homo sapiens_hsa04360 | 0.21643753 |
119 | Cell cycle_Homo sapiens_hsa04110 | 0.21607681 |
120 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.20755917 |
121 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 0.20410722 |
122 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.19962279 |
123 | Peroxisome_Homo sapiens_hsa04146 | 0.19684002 |
124 | Gastric acid secretion_Homo sapiens_hsa04971 | 0.18875084 |
125 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 0.18742525 |
126 | Insulin secretion_Homo sapiens_hsa04911 | 0.18361280 |